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DETERMINATION OF METRONIDAZOLE MICROPARTICLE CONTENTS IN THE HEMISELLULOSE MATRIX OF CORN COB USING ULTRAVIOLET SPECTROPHOTOMETRY Dalimunthe, Gabena Indrayani; Rani, Zulmai; Rambe, Robiatun
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 9, No 2 (2024): September
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v9i2.2607

Abstract

Microparticles can be an accurate drug delivery agent, reducing drug concentration in the target and providing an effective delivery system for substances that are slightly soluble in water. Corn cobs contain the most hemicellulose, and this hemicellulose can be employed as a matrix to restrict medication release if administered orally. The purpose of this study is to use UV spectrophotometry to evaluate the concentration of metronidazole microparticles in the hemicellulose matrix of corn cobs. This research is divided into two stages: separating hemicellulose from corn cobs and characterization of hemicellulose, which includes visual organoleptics, taste, smell, and form. Solubility test in alkaline conditions (NaOH), followed by FTIR test using the KBr pellet method with typical peaks seen in the FTIR spectrum, SEM test to get structural morphology, and PSA test to determine particle size and distribution of representative samples. After the microparticles are formed, further characterization is carried out, including an organoleptic test, solubility test, PSA test, FTIR test, and SEM test. Next, the levels of metronidazole microparticles in the corncob hemicellulose matrix were determined using ultraviolet spectrophotometry by comparing metronidazole tablets on the market. The concentration of metronidazole microparticle sample in the corncob hemicellulose matrix was determined to be 80.12 0.5290%, and the concentration of metronidazole tablets on the market was 100.51 0.7576%, which meets the requirements for metronidazole tablet concentration, namely not less than 90.0% and not more than 110% of the amount stated on the label.
Sosialisasi DAGUSIBU (Dapatkan, Gunakan, Simpan, Buang) Obat Dengan Benar pada Masyarakan di Desa Pematang Cermai Humaira, Annisa; Maghfirah, Dini; Nisa, Uswatun; Rani, Zulmai; Intan Annisa Puteri, Cut
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2024): Edisi Januari 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v4i1.761

Abstract

Salah satu cara untuk meningkatkan kesehatan masyarakat adalah melalui kegiatan pelayanan kesehatan yang dilakukan oleh tenaga kefarmasian. adalah "Dagusibu", yakni "Dapatkan, Gunakan, Simpan, dan Buang". Tenaga kefarmasian dapat memberikan pelayanan kesehatan pada masyarakat dengan memberikan pemberitahuan tentang penggunaan dan penyimpanan obat-obatan dan alat medis. Kegiatan dilakukan melalui sosialisasi atau penyuluhan. Alat bantu, seperti leaflet atau brosur DAGUSIBU, digunakan untuk memberikan informasi kepada peserta sosialisasi. Peserta sosialisasi adalah ibu-ibu. PKK, kader posyandu, dan masyarakat. Materi yang dijelaskan dalam sosialisasi berupa teori umum DAGUSIBU diikuti dengan pemaparan tentang jenis sediaan obat dan cara penggunaannya, yang mencakup aspek 4T dan 1W: Obat harus diberikan dengan benar sesuai dengan indikasi, dosis yang tepat, kondisi pasien yang tepat, dan penggunaan yang tepat sambil memperhatikan efek sampingnya. Selain itu, dibahas tentang hal-hal yang harus diperhatikan saat menangani obat, seperti memeriksa tanggal kadaluarsa obat dan memastikan penggunaan obat dengan benar. Pemateri memberikan penjelasan dan praktik penggunaan obat dalam bentuk sediaan, seperti suppositoria, salep mata, obat tetes mata, semprot mulut, semprot hidung, dan tetes telinga. Pengabdian menunjukkan bahwa masyarakat mulai memahami cara mendapatkan, menggunakan, menyimpan, dan membuang obat dengan benar. Komunitas DAGUSIBU tentang penggunaan dan penanganan obat berjalan dengan baik. Saya berharap kegiatan ini akan membantu peserta menerapkan pengetahuan yang mereka peroleh di dalam keluarga dan masyarakat mereka.
Pembuatan Sediaan Roll On Penghilang Bau Badan Dari Kulit Jeruk Purut Di Kalangan Mahasiswa Universitas Harapan Medan Indrayani Dalimunthe, Gabena; Sartika Daulay, Anny; Rani, Zulmai; Rambe, Robiatun
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 4 No. 1 (2024): Edisi Januari 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v4i1.797

Abstract

Bau badan merupakan keluhan umum yang sering diungkapkan oleh masyarakat di daerah tropis, seperti Indonesia, dan seringkali menjadi gangguan dalam kehidupan sehari-hari. Orang dapat kehilangan kepercayaan diri jika mereka memiliki bau tubuh yang tidak sedap. Salah satu cara untuk mengatasi masalah ini adalah dengan menggunakan deodoran, tetapi deodoran biasanya mengandung bahan kimia yang dapat menyebabkan iritasi kulit. Untuk mengatasi masalah ini, kita bias membuat deodoran yang terbuat dari bahan-bahan alami. Sasaran kegiatan ini adalah mahasiswa dari Fakultas Bahasa dan Komunikasi di Universitas Harapan Medan. Kegiatan ini melibatkan pelatihan pembuatan deodoran menggunakan bahan alami, khususnya daun jeruk purut. Tujuan dari inisiatif ini adalah untuk mengoptimalkan pengelolaan sumber daya alam, mendorong mahasiswa untuk terlibat dalam wirausaha melalui pembuatan deodoran ala home industri. Selain itu, kegiatan ini bertujuan untuk mengajarkan cara membuat deodoran stik secara sederhana, terutama untuk mahasiswa jurusan bahasa dan komunikasi yang mungkin belum familiar dengan formulasi bahan alami. Penambahan komponen-komponen alami ini dapat meningkatkan efektivitas deodoran sambil meminimalkan risiko iritasi kulit. Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah untuk mendorong penggunaan sumber daya lokal dan mendukung praktik berkelanjutan dalam pengembangan produk perawatan pribadi.
Pemanfaatan Ekstrak Bahan Alam Pada Sabun Cuci Piring di Desa Sidomulyo Kecamatan Biru-Biru, Deli Serdang Yuniarti, Rafita; Sari Lubis, Minda; Munandar Nasution, Haris; Rani, Zulmai; Linda, Rosa; Adjelie, Tiara
Jukeshum: Jurnal Pengabdian Masyarakat Vol. 4 No. 2 (2024): Edisi Juli 2024
Publisher : Universitas Haji Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51771/jukeshum.v4i2.933

Abstract

Salah satu penyakit yang masih banyak terdapat di Masyarakat Indonesia adalah penyakit infeksi, yang dapat disebabkan oleh bakteri ataupun virus. Penyakit infeksi yang disebabkan oleh bakteri dapat diatasi dengan antibakteri, sedangkan infeksi yang disebabkan oleh virus dapat diatasi dengan menggunakan antivirus. Salah satu penyebab sering munculnya penyakit infeksi adalah karena hygiene dan sanitasi yang buruk. Penggunaan antibakteri dari bahan alam merupakan salah satu cara yang aman dalam mengatasi masalah tersebut. Tujuan: meningkatkan pengetahuan Masyarakat tentang bahan alam yang berkhasiat sebagai antibakteri dan pemanfaatan bahan alam dalam sediaan perbekalan Kesehatan rumah tangga (PKRT). Metode: penyuluhan tentang tumbuhan yang berkhasiat sebagai antibakteri dan pembuatan sabun cuci piring menggunakan ekstrak daun jeruk kuok (Citrus nobilis). Hasil: pada penyuluhan tentang tumbuhan yang digunakan sebagai antibakteri diperoleh Tingkat pengetahuan sebesar 61% dan setelah kegiatan diperoleh hasil Tingkat pengetahuan sebesar 82% sedangkan pada kegiatan pembuatan sabun cair dengan bahan alam sebagai antibakteri diperoleh hasil 58% dan setelah kegiatan sebesar 93%. Kesimpulan: Terjadi peningkatan pengetahuan tentang tumbuhan yang berkhasiat sebagai antibakteri sebesar 21% dan peningkatan pengetahuan tentang pembuatan sabun cuci piring dengan bahan alam sebesar 35%.
Uji Efektivitas Ekstrak Jamur Susu Harimau (Lignosus rhinocerus) Sebagai Antioksidan dengan Metode DPPH: Test of the Effectiveness of Tiger Milk Fungus (Lignosus rhinocerus) Extract as an Antioxidant by DPPH Method Rambe, Robiatun; Rani, Zulmai; Ginting, Ovalina Sylvia Br; Fauzi, Ziza Putri Aisyia
Jurnal Sains dan Kesehatan Vol. 6 No. 3 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i3.2117

Abstract

Chemicals including alkaloids, flavonoids, tannins, saponins, and steroids are present in tigers milk mushrooms (Lignosus rhinocerus). This work compares the IC50 value of tiger milk mushrooms and assesses the antioxidant activity of ethanol extract. This study employed maceration as the extraction technique, utilizing a 1:10 ratio of 96% ethanol solvent. The antioxidant activity was assessed using the DPPH free radical reduction technique. Based on antioxidant activity studies, the tiger milk mushroom ethanol extract's IC50 value was 149.26 ppm, while vitamin C's was 3,238 ppm. Antioxidant activity was detected in the ethanol extract of tiger milk mushrooms, with an IC50 value of 19,206 ppm and an IC50 value of 3,238 ppm, suggesting that the antioxidant activity was in the middle range. But compared to the ethanol extract of tiger milk mushrooms, the vitamin C IC50 value was greater. Keywords:          Lignosus rhinocerus, Antioxidant activity, DPPH method   Abstrak Jamur susu harimau (Lignosus rhinocerus) memiliki kandungan kimia seperti alkaloid, flavonid, tanin, saponin dan steroid. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ekstrak etanol serta perbandingan nilai IC50 dari jamur susu harimau. Metode Ekstraksi yang digunakan dalam penelitian ini adalah maserasi menggunakan pelarut etanol 96% dengan perbandingan 1:10. Pengujian aktivitas antioksidan menggunakan metode peredaman radikal bebas DPPH. Dari hasil pengukuran aktivitas antioksidan diperoleh nilai IC50 ekstrak etanol jamur susu harimau sebesar 149,26 ppm dan vitamin C sebesar 3,238 ppm. Aktivitas antioksidan dari ekstrak etanol jamur susu harimau diperoleh dengan nilai IC50 ekstrak etanol jamur susu harimau sebesar 19,206 ppm dan vitamin C sebesar 3,238 ppm dimana aktivitas antioksidan tergolong kategori sedang, tetapi nilai IC50 vitamin C lebih baik dibandingkan ekstrak etanol jamur susu harimau. Kata Kunci:         Lignosus rhinocerus, Aktivitas antioksidan, Metode DPPH
Antimicrobial Activity Test of Ethanol Extract of Senggani Leaves (Melastoma malabraticum L) Against Propionibacterium Acnes and Staphylococcus Epidermidis Nasution, Haris Munandar; Rani, Zulmai; Fauzi, Ziza Putri Aisyia; Ridho, Ahmad Rasyid
Jurnal Sains dan Kesehatan Vol. 6 No. 2 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i2.2208

Abstract

Senggani leaves are a plant that can be found in Indonesia, including hilly locations. The people of Marendal, Patumbak subdistrict, believe that senggani leaves may heal minor skin wounds. The goal of this study was to identify the class of secondary metabolite chemical compounds and their antibacterial efficacy against the microorganisms Propionibacterium acnes and Staphylococcus epidermidis at 5, 10, and 20% concentrations. The ethanol extract of senggani leaves contains secondary metabolite compounds with antibacterial activity. According to the antibacterial test results, a 20% ethanol extract of senggani leaves is effective against Propionibacterium with a diameter of 10.7 mm, a 10% in the medium category with a diameter of 9.27 mm, and a 5% in the medium category with a diameter of 8.8 mm. Meanwhile, the diameter of Staphylococcus epidermidis at a 20% was 8.77 mm in the medium category, 8.37 mm at 10%, and 8.6 mm at a 5% concentration.   Keywords:          Propionibacterium acnes, Senggani leaves, Staphylococcus epidermidis
Pengaruh gel ekstrak induk kunyit (Curcuma longa linn) terhadap penyembuhan luka sayat pada tikus putih jantan (Rattus norvegicus) Kaban, Vera Estefania; Nasri, Nasri; Rani, Zulmai; Suci, Nurul; Karo Sekali, Elva Swandi; Sagala, Hasel Untung Bersinar
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.590

Abstract

One plant that has been shown to aid wound healing is turmeric. Turmeric has been scientifically proven to have choleretic and anti-inflammatory properties. Turmeric contains curcumin, which has antibacterial and antioxidant qualities that can accelerate the migration and re-epithelialization of cells useful in wound healing, including myofibroblasts, fibroblasts, and macrophages. This study aimed to determine the effect of turmeric mother extract gel on wound healing in male white rats (Rattus norvegicus). This study was conducted using experimental tests. Turmeric extract was prepared using 96% ethanol solvent with a maceration process. A 2 cm long incision wound was made on the back of white rats. The test animals were then divided into five groups to receive different treatments. Groups 3, 4, and 5 received turmeric mother extract gel with concentrations of 1%, 5%, and 10%, while Group 1 was negative control and Group 2 was positive control. The results showed that the incision wounds in male white rats could heal faster - on average, about 7.10 days - when treated with 96% ethanol extract of turmeric mother with doses of 1%, 5%, and 10%. This study concludes that a 10% turmeric mother extract gel is the best method to accelerate wound healing.
Formulasi masker wajah serbuk nano teh celup bekas dan aktivitas antibakteri terhadap Propionibacterium acnes dan Staphylococcus epidermidis Matondang , Fikriyah Hafni; Lubis, Minda Sari; Yuniarti , Rafita; Rani, Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.685

Abstract

The increase in the cosmetic industry has caused a variety of facial mask products to circulate on the market, making it difficult for consumers to find one that suits their skin condition. Masks from well-known brands are easy to get, but some cause skin problems. Since ancient times, Indonesians have used plants as medicines and cosmetic ingredients for skin care. Tea can be processed into new active ingredients such as antioxidants, antibacterials, and anti-aging for cosmetics. Nanoparticle-based cosmetics are superior to micro-scale cosmetics. The objective of the research was to determine whether used tea bag powder meets the characteristic requirements as nanopowder, to determine whether used tea bag nanopowder in facial mask preparations meets the physical quality requirements, and to determine whether used tea bag nano powder facial mask preparations has antibacterial activity against Propionibacterium acnes and Staphylococcus epidermidis. This research method was true experimental with post test only control group design research design. The independent variables are tea bag powder and nanopowder and powder face mask formulation variations. The dependent variables are the characteristics of the simplicia, secondary metabolites, nanopowder characteristics, powder face mask formulation, and antibacterial activity test. The results showed that tea bag powder and nanopowder contained alkaloid, steroid, flavonoid, saponin, and tannin compounds. The inhibitory activity of the used tea bag nano powder mask on Propionibacterium acnes was 11.3 mm on Staphylococcus epidermidis, which was 11.2 mm. The tea bag powder used meets the characteristics of a nanopowder with a particle size of 684 nm. I used a tea bag nanopowder to prepare a face mask that meets the physical quality requirements.
Pembuatan nanoekstrak dari kulit buah jeruk kasturi (Citrus microcarpa) dan formulasinya sebagai pasta gigi Hasibuan , Fika Miah Sasmitha; Dalimunthe, Gabena Indrayani; Lubis , Minda Sari; Rani, Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.694

Abstract

Dental caries is a common oral health problem among the Indonesian population, and its primary cause is the bacterium Streptococcus mutans. The peel of the Kasturi orange (Citrus microcarpa) fruit has been known to contain antibacterial properties, which may help prevent the occurrence of dental caries. This study aims to evaluate the toothpaste formulation with the active ingredient of nano-extract from kasturi orange peel (Citrus microcarpa). The extract of Kasturi orange peel was obtained through a maceration method, followed by phytochemical screening that identified the presence of flavonoids, steroids, alkaloids, saponins, glycosides, and essential oils. The extract was then processed into a nano-extract, and its particle size was measured using a Particle Size Analyzer (PSA) with a dynamic light scattering technique. The nano-extract was formulated into toothpaste at concentrations of 7.5%, 10%, and 12.5%, and its antibacterial activity was tested. Physical evaluations showed that the toothpaste maintained its shape, color, odor, and taste during storage, was homogeneous, had a pH within the acceptable range (4.5–10.5), viscosity within the required range (20,000–50,000 cps), and passed organoleptic testing (color, aroma, taste, and texture) on respondents.
Formulation of nanocream whitening preparation from a combination of yam starch (Pachyrhizus erosus L.) and rice starch (Oryza sativa L.) Nur, Hijrotun; Dalimunthe, Gabena Indrayani; Rani, Zulmai; Yuniarti, Rafita
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.698

Abstract

Whitening cosmetics have become a popular choice in modern society, with the perception that beauty is associated with white skin. The high market demand is an opportunity for cosmetic business actors but it also increases the risk of illegal cosmetic production containing hazardous materials such as hydroquinone. One of the cosmetic ingredients that is often found in whitening creams containing hydroquinone, which is effective in removing dark spots, has the risk of serious side effects. Therefore, it is advisable to find a safe, natural alternative for long-term skin whitening. Jicama starch and rice water starch are natural choices for whitening cosmetics. Nanoparticle-based cosmetics are superior to micro-scale cosmetics. The objective of the research was to determine whether a combination of jicama starch and rice water starch whitening cream can meet the characteristic requirements of a nano cream, to determine all concentrations of jicama starch and rice water starch whitening nano cream that meet the physical quality requirements and to determine all concentrations of jicama starch and rice water starch whitening nano cream have different effectiveness. This research method was True Experimental with Post Test Only Control Group Design research design. The independent variables are variations in the concentration of yam starch and rice water starch. The dependent variables were sample characteristics, characteristics of the whitening nano cream formulation and nano cream effectiveness test. The results showed that yam starch and rice water starch had effectiveness as whitener with a concentration of f3 (5:5) water content of 55.67%, sebum of 16% and pigment of 15.67%. The whitening cream met the characteristics of a nano cream with particle sizes of f0: 134.04, f1: 1849.20, f2: 147.64 and f3: 188.14 nm. Yam starch and rice water starch in the preparation of the whitening nano cream meet the physical quality requirements.
Co-Authors A'dilah, Nur Abadi, Hafizhatul Adjelie, Tiara Adli Nuzula Rahmah Adyani Maulinda Afriati, Nelsi Afridah, Nurul Ilmi Ahmad Rasyid Ridho Alviana, Liya Amelia Kudadiri Andi Syahputra, Ricky Andjelie, Tiara Ani Sutiani Ani Sutiani Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Aprilia, Hijjatun Arifin, Khairil Fikri Arrosty, Muflizah Athaillah, Athaillah Audry Pratiwi Aulia Fitri Aulia Fitri, Aulia Auza , Maharani Azhar, Gustika Bambang Hermanto Bambang Hermanto Beby Noplya Wulandari BJ Sutrisna Chandra, Putra Dama Yanti, Fradilla Daulay, Anny S. Dea Anggreini Denny Satria Dewi, Sri Harti Dikki Miswanda Dinda Sari Utami Dwi Jati, Fatma Erma Susanti Evi Depiana Gultom Evi Depiana Gultom Fadhlah Al-Uyun Nasution Fahmi Fahmi Fajri, Fajrilda Aqilah Fauziah Erna Witular Panggabean Ferendina, Imelda Fithri Pulungan, Ainil Fitri, Nurul Fitri, Raissa Gabena Indrayani Dalimunthe Ginting, Grace Anastasia br Ginting, Ovalina Sylvia Br Ginting, Ovalina Sylvia Br. Gultom, Evi Depiana Hanafis Sastra Winata Harahap, Sumiyarni Haris Munandar Nasution Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hasibuan , Fika Miah Sasmitha Hasibuan , Nabila Hasim Hasibuan, Zulfiana Ramadhani Hindri Syahputri Humaira, Annisa Husna, Miftahul Hutagalung, Victor H Indrayani, Gabena Inna Myesha Julia Reveny Karo Sekali, Elva Swandi Kasta Gurning Khairunnisa , Ardina Khan, Sahrani Nazwa Kiki Rawitri Kiki Rawitri Lestari, Amanda Putri Lestari, Kurnia Dwi Lilik Septiana Lilik Septiana Linda, Rosa Lubis, Asira Lubis, Minda Sari lubis, muhammad fauzan Lubis, Nurazizah M. Alfaruqi Maghfirah, Dini Mainal Furqan Malahayati Malahayati Maryanti Yuza Matondang , Fikriyah Hafni Maulana Putri, Yasinta Mira Febrina, Mira Monica Suryani Moondra Zubir Muhammad Agus Muljanto Muhammad Amin Nasution Muhammad Fauzan Lubis Muhammad Yunus Muhammad Yunus Mukti, Ridho Munandar, Verissa Nadila Indra Sepvina Nasri Nasri Nasri Nasri Nasri Nasri, Nasri Nasution, Wardah Nazuhra, Oca Nia Novranda Pertiwi Nindya Indah Damayanti Ningtias, Anggita Ningtias, Anggitha Nomi Noviani Nur Ain Thomas Nur, Hijrotun Nurdalilah, Nurdalilah Nurhayati Nurhayati Nurmazela, Virda Nursyafira, Arini Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Paramitha, Ratih Parapat , Anjarlit Romiyuliana Br Pasar Maulim Silitonga Pertiwi, Rahma Pitaloka, Syifa Amilia Puspita, Dinda Dila Puteri, Cut Intan Annisa Putra, Andhika Dharma Putri Khairani Rahma Dona, Rahma Raissa Fitri Rambe, Robiatun Rawitri, Kiki Reza Irma Ricky Andi Syahputra Ridho, Ahmad Rasyid Ridwanto Ridwanto Ridwanto Rinda Sari, Syilvi Rinda Sari, Sylvi Ritonga , Nur Sakina Rizki, Dewi Rizki, Vitri Dea Robiatun Rambe Robiatun, Robiatun Rambe Ronapadua Musyirna Rahmah Nasution Sahara dan Emma Susanti Rukmana, Siti Sagala, Hasel Untung Bersinar Samran, Samran Sari Lubis, Winda Sari, Farida Sari, Syilvi Rinda Sari, Sylvi Rinda Sartika Daulay, Anny Savitri, Novia Herma Septiana, Lilik silalahi, zahra salsabila Sindi, Sindi Sipahutar, Rizki Anjani Siregar , Misbah Siti Anisa Siti Rahmah Siti Rahmi Ningrum Sony , Suyefri Sri Wahyuni Sri Wahyuni Suci, Nurul Sulwiyatul K Sani Supiyani, Supiyani SURBAKTI, CHRISTICA ILSANNA Syafa Nadira Ashiilah Syahputra, Ricky Andi Syarifah Nadia Syilfia Hasti Tania, Chyntia Glori Tarigan, Eni Surabini Trizaldi, Asep Urip Harahap Uswatun Nisa, Uswatun Vera Estefania Kaban Widya, Rizka Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Haryani Yuliatil Adawiyah Harahap Yuniarti , Rafita Yuniarti, Rafita Zahira Ahmad, Madani Ziza Putri Aisyia Fauzi Zulfikri Zulfikri Zulhij, Fizrya