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All Journal Majalah Kedokteran Bandung Medula Juke Indonesian Journal of Cancer Turbo : Jurnal Program Studi Teknik Mesin Jurnal Aplikasi Teknologi Pangan Jurnal Pengabdian Pada Masyarakat Jurnal Aplikasi Teknologi Pangan Jurnal Ilmu Kedokteran dan Kesehatan Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Kesehatan Ilmiah Indonesia / Indonesian Health Scientific Journal Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Jurnal Mandala Pengabdian Masyarakat Jurnal Kesehatan Tambusai MAHESA : Malahayati Health Student Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research International Journal of Health and Pharmaceutical (IJHP) JUSTICIA SAINS: Jurnal Ilmu Hukum Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) Sains Medisina Jurnal Riset Ilmu Kesehatan Umum dan Farmasi JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai BEGAWI: Jurnal Pengabdian Kepada Masyarakat Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Asep Sukohar
Department Of Pharmacology; Faculty Of Medicine; Universitas Lampung
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Medication Adherence and Glycemic Control among Patients With Type 2 Diabetes Enrolled in a Chronic Disease Management Program in Primary Care Settings Sukohar, Asep; Emily Rachman, Reimma; Abighail, Nistita; Eva Lusina, Septia; Akmal Ghani, Muhammad
International Journal of Health and Pharmaceutical (IJHP) Vol. 6 No. 1 (2026): February 2026
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v6i1.571

Abstract

Medication adherence plays a crucial role in achieving optimal glycemic control in patients with type 2 diabetes mellitus. However, poor glycemic control remains common despite the availability of antidiabetic therapy through the Chronic Disease Management Program (Prolanis), and evidence regarding this association among program participants is still limited. This study aimed to analyze the association between antidiabetic medication adherence and glycemic control based on HbA1c levels in patients with type 2 diabetes mellitus enrolled in Prolanis. An analytical observational study with a cross-sectional design was conducted among 118 Prolanis participants at primary health care facilities in Lampung Province, Indonesia, in 2025 using consecutive sampling. A total of 118 respondents were included in the final analysis, with a mean age of 54.09 ± 10.66 years. Medication adherence was assessed using the Morisky Medication Adherence Scale-8, while glycemic control was evaluated based on HbA1c categories. Data were analyzed using the Chi-square test with a significance level of p < 0.05. The results showed that most respondents had moderate medication adherence (38.1%) and poor glycemic control (50.8%). A significant association was found between medication adherence and glycemic control (p = 0.037; Cramér's V = 0.208), indicating a small-to-moderate effect size. These findings highlight the need to strengthen adherence-focused interventions, including patient education, routine monitoring, and continuous support, as part of Prolanis implementation to improve long-term glycemic outcomes in primary care settings.
Review Artikel: Rasionalitas Penggunaan Obat Antihipertensi Pada Pasien Geriatri di Pelayanan Kesehatan Primer Angelica Dwita Handayani; Rani Himayani; Muhammad Fitra Wardhana Sayoeti; Asep Sukohar
Sains Medisina Vol 4 No 4 (2026): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v4i4.1036

Abstract

Hipertensi merupakan penyakit kronis dengan prevalensi tinggi, terutama pada pasien geriatri, dan sering kali memerlukan terapi jangka panjang menggunakan obat antihipertensi. Penggunaan obat yang tidak rasional dapat menurunkan efektivitas terapi serta meningkatkan risiko efek samping. Oleh karena itu, evaluasi rasionalitas penggunaan obat antihipertensi menjadi penting, khususnya di pelayanan kesehatan primer. Penelitian ini bertujuan untuk mengkaji rasionalitas penggunaan obat antihipertensi pada pasien geriatri di pelayanan kesehatan primer. Metode yang digunakan adalah tinjauan naratif terhadap artikel ilmiah yang diperoleh dari PubMed, ScienceDirect, dan Google Scholar dengan rentang tahun 2015–2025. Artikel yang memenuhi kriteria inklusi dianalisis secara deskriptif. Hasil penelusuran menunjukkan bahwa penggunaan obat antihipertensi pada pasien geriatri umumnya telah memenuhi kriteria rasionalitas, terutama pada aspek tepat indikasi, tepat pasien, dan tepat dosis. Obat yang paling banyak digunakan adalah amlodipin dari golongan calcium channel blocker (CCB), baik sebagai terapi tunggal maupun kombinasi. Namun, masih ditemukan ketidaktepatan pada pemilihan obat dan regimen terapi pada beberapa kasus. Kesimpulannya, penggunaan obat antihipertensi pada pasien geriatri di pelayanan kesehatan primer secara umum sudah rasional, tetapi tetap diperlukan evaluasi berkelanjutan untuk meningkatkan efektivitas dan keamanan terapi.
Review Article: Pengaruh Durasi Maserasi terhadap Aktivitas Antibakteri Daun Kelor (Moringa oleifera) pada Escherichia coli Nisrina Zalfa Fatin; Tri Umiana Soleha; Shinta Nareswari; Asep Sukohar
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1746

Abstract

The increasing resistance of bacteria to antibiotics has encouraged the use of medicinal plants as a natural alternative antibacterial agent. Moringa leaves (Moringa oleifera) contain bioactive compounds, including flavonoids, tannins, saponins, alkaloids, and terpenoids, which are capable of inhibiting bacterial growth. This review article aims to examine the effect of maceration duration using 96% ethanol as a solvent on the antibacterial activity of Moringa oleifera leaf extracts against Escherichia coli. Literature searches were conducted through PubMed, Google Scholar, and Scopus, using a combination of keywords such as “Moringa oleifera,” “leaf extract,” “ethanol,” “maceration time,” and “antibacterial activity,” with a limitation to publications from the last ten years. Relevant articles were selected based on their focus on ethanol extraction of Moringa oleifera leaves and antibacterial testing against E. coli. Recent studies indicate that variations in maceration duration result in differences in inhibition zone diameters ranging from 9.83 to 27.7 mm. Short-term maceration of 24 hours can achieve high antibacterial activity, whereas longer maceration does not necessarily enhance effectiveness. These differences are influenced by extract concentration, bioactive compound stability, and bacterial testing conditions. These findings highlight that the antibacterial effectiveness of Moringa oleifera leaves depends on an optimal combination of maceration duration, extract concentration, and the stability of active compounds. Determining the appropriate maceration time is crucial for achieving maximum antibacterial activity. Furthermore, these results provide a basis for future research on the utilization of Moringa oleifera leaf extracts as a potential natural antibacterial agent.
Literature Review: Penggunaan Obat Off-label pada Pasien Pediatri Chintia Dwi Tanasa; Nurma Suri; Citra Yuliyanda Pardilawati; Asep Sukohar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.682

Abstract

 Off-label drug use is still widely found, especially among vulnerable patients. Pediatrics is one of the vulnerable patient groups who still often get off-label drug therapy. This study was conducted with the aim of looking at the description of the use of off-label drugs given to pediatric patients. This research is a type of research with the literature review method, with data obtained from several articles, the search for articles was carried out through the Google Scholar database. The results of this study from 10 articles used as research data, found the use of off-label drugs in pediatric patients with the most results in the off-label dosage category and followed by off-label dosage category, off-label age category, and off-label route of administration category, while the off-label contraindication category was not found. Based on the results obtained, it is concluded that the use of off-label drugs in pediatric patients is quite high, so it is necessary to monitor the use of off-label drugs to reduce the incidence of unwanted side effects  
Perbedaan Antara Tingkat Kepuasan Pasien Layanan Kefarmasian di Puskesmas Induk Natar dan Puskesmas Rajabasa Indah Lani Hartanti; Rasmi Zakiah Oktarlina; Zulpakor Oktoba; Asep Sukohar
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 3 No. 3 (2025): Juli : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v3i3.787

Abstract

Background: Pharmaceutical services at primary health centers (puskesmas) play a vital role in supporting the quality of primary healthcare services. However, patient satisfaction with these services varies, influenced by factors such as service quality and demographic characteristics of the patients. In Lampung Province, the Induk Natar and Rajabasa Indah primary health care centers have different regional characteristics, which may influence patients perceptions and satisfaction with pharmaceutical services. Methods: This study employed an analytical observational method with a cross-sectional design. Samples were selected using systematic accidental sampling, with 100 respondents from each primary health care centers. Quantitative data were collected using the Servqual questionnaire and patient sociodemographic characteristics. Data were analyzed using the Mann-Whitney test and the Chi-Square test. Result: The reliability dimension showed the highest satisfaction level in both Induk Natar primary health care centers (90.10%) and Rajabasa Indah primary health care centers (94.05%). Conversely, the tangible dimension had the lowest satisfaction levels, with 88.60% in Induk Natar primary health care centers and 92.08% in Rajabasa Indah primary health care centers. A significant difference in patient satisfaction levels was found between the two health centers. However, no significant correlation was found between patient characteristics (age, gender, education, and occupation) and satisfaction levels (p-value > 0.05). Conclusion: Rajabasa Indah primary health care centers demonstrated a higher level of patient satisfaction compared to Induk Natar primary health care centers. A significant difference in satisfaction levels between the two centers was confirmed by the Mann-Whitney test.
Co-Authors A.Yudi Eka Risano Abighail, Nistita Aditya Ramadhon Islami Sakaganta Afriyana, Regi Afriyani Afriyani Aghesna Rahmatika Kesuma Ahmad Fitri, Ahmad Akbar, Muhammad Zakky Putra Akmal Ghani, Muhammad Ali, Nur Fitriana Muhammad Alifah, Ghina Nur Ambarwati, Endah Aminuyati Andi Nafisah Andi Nafisah, Andi Angelica Dwita Handayani Anisa Nuraisa Jausal Anita Febrina, Anita Aqsha, Shabita Arianti, Tanti Arief B Witarto Ariyati, Retno Desy Arli Suryawinata Arli Suryawinata Arsyad Sobby Kesuma Aulia Ramdini, Dwi Aulian Mediansyah Baddarudin, Mohammad Bainah Sari Dewi Betta Kurniawan, Betta Chintia Dwi Tanasa Christine Wulandari Citra Yuliyanda Pardilawati Damayanti, Ervina Daulay, Suryani Agustina Dharmesti, Rizky Aleyda Dyah Indriana Kusumastuti Elisa, Syavira Emily Rachman, Reimma Endah Ambarwati Endah Setyaningrum, Endah Endro Prasetyo Wahono Eva Lusina, Septia Fala, Arzety Rifda Farhan Akbar, Muhamad Febriyanti, Triana Fibra Nurainy Fitria Saftarina Fredison, Fredison Gerliandi, Egi Oktarian Hanna Mutiara, Hanna Hardito, Joni Hatimi, Fahmi Ilham Hendra Tarigan Sibero HENING HERAWATTI, HENING Herri S. Sastramihardja Ida Nurhaida Ihsanti Dwi Rahayu Indri Windarti Intan Kusumaningtyas Irza Sukmana, Irza Jausal, Anisa Nuraisa Josi Jeremia Manurung Junando, Mirza Karima, Nisa Kaskoyo, Hari Kurniawaty, Evi Kylalona, Gracylia L.P, Eka Ananda Lani Hartanti LP, Eka Ananda Maherariyat, Maherariyat Mallarangeng, Andi Nafisah Tendri Adjeng Mediansyah, Aulian Morfi, Chicy Widya Muhammad Fitra Wardhana Sayoeti Muhammad Iqbal Muhammad Iqbal Ramadhan Muhartono Muhartono Muhartono Muhartono Muhartono Mukhlis Imanto Mutiara, Sephia Aruma Nisa, Sayyidatun Nisrina Zalfa Fatin Noverman Duadji Noviani, Erina Novita Carolia Novita Herdiana Novita Tresiana NUR AFRIYANI Oktafany, Oktafany Oktoba, Zulpakor Pardilawati, Citra Yuliyanda Permana, Km. Allan Wahyu Permana, M. Agung Yudistira Puteri, Vadiyani Fricillya Putri Idrus, Indrayati Putri, Asyifa Adinda Putri, Meilani Putri, Meilani Dwi Putri, Oka Mahila Gustia Ramadhan Triyandi Ramadhina, Farrasyifa Ramdini, Dwi Aulia Rani Himayani Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Ratna, Maya Ganda Rika Lisiswanti Rizqa Atina Safitri, Nara Said, Feriany Salam, Deby Mipa Samsu Udayana Nurdin Samsu Udayana Nurdin Samsul Bakri Samsul Rizal Santika, Mesi Sepriyadi Adhan S Setiawan, Gigih Shinta Mayasari Shinta Nareswari Siboro, Erwi Saulina Venezia Slamet Budi Yuwono Sofyan Musabiq Wijaya Sofyan Musyabiq Wijaya Subeki Sugiyanto - Suharmanto Suharyani Suharyani Suharyani Sumekar, Diyah Suri, Nurma Suryadi Islami Suryawinata, Arli Sutarto Sutarto Sutarto Sutarto Syazili Mustofa Thahir, Salsabila Anggraini Tri Umiana Soleha Trijayanthi, Winda Triyandi, Ramadhan Wahdah, Annisa Shohifatul Wardani, Farah Dwi Wardhana S, Muhammad Fitra Wardhana, M. Fitra Wijaya, Sofyan Wijaya, Sofyan Musabiq Winda Trijayanthi Utama, Winda Trijayanthi WS, Muhammad Fitra Yofita Sulfiana Sundari Zeta, Nathasya Karren