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All Journal Biospecies Jurnal Kedokteran Brawijaya JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) BERITA BIOLOGI The Indonesian Biomedical Journal Lantanida Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Kesehatan Komunitas Window of Health : Jurnal Kesehatan Indonesian Journal of Medicine Jambura Journal of Health Sciences and Research Journal Health & Science : Gorontalo Journal Health and Science Community Jurnal Kesehatan Poltekita : Jurnal Ilmu Kesehatan Jurnal Keperawatan Priority Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Prima Medika Sains An-Nadaa: Jurnal Kesehatan Masyarakat AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Jurnal Inovasi Pendidikan dan Sains Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K) Jurnal Ilmiah METADATA Eureka Herba Indonesia Jurnal Kesehatan Tambusai MAHESA : Malahayati Health Student Journal Journal of Multidisciplinary Applied Natural Science Interdisciplinary Social Studies Jurnal EduHealth Journal of Current Health Sciences International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Jurnal Locus Penelitian dan Pengabdian Jurnal Sains dan Teknologi Buletin Kedokteran dan Kesehatan Prima Pharmaceutical Sciences and Research (PSR) International Journal of Health and Pharmaceutical (IJHP) International Journal of Science and Environment Eduvest - Journal of Universal Studies Journal of Pharmaceutical and Sciences. Blantika : Multidisciplinary Journal Malahayati International Journal of Nursing and Health Science

Chiuman, Linda

Universitas Prima Indonesia

Author-ID : 1391724

Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Analyzing Ethanol’s Antioxidant Extract of Pandanus Leaves through DPPH Method Hardianti, Siti; Chiuman, Linda; Ginting, Chrismis Novalinda; Adrian, Adrian
Interdisciplinary Social Studies Vol. 1 No. 5 (2022): Special Issue
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/iss.v1i5.128

Background: Aging is a natural process and no one can avoid it. The aging process is also a physiological process that will occur in all living things. This process covers all organs of the body including the skin which is one of the body tissues that directly shows the occurrence of the aging process Aim: This research aims to analyze ethanol’s antioxidant extract of pandanus leaves through DPPH method. Method: This type of research is using experimental research designs to determine the antioxidant activity affected by time, and temperature with the DPPH method, a formulation of the effects of the ethanol extract of fragrant pandan leaves (Pandanus amaryllifous Roxb). Findings: It has active antioxidant activity and IC50 extract of fragrant pandan ethanol on the 5th day with a temperature of 50° C and on the 3rd day with a temperature of 35° C which is the best antioxidant activity.

- EFEKTIVITAS PRP TERHADAP PERUBAHAN PROFIL LIPID DARAH TIKUS PUTIH JANTAN (Rattus Norvegicus) DIABETES MELITUS YANG DI INDUKSI STREPTOZOTOCIN: EFEKTIVITAS PRP TERHADAP PERUBAHAN PROFIL LIPID DARAH TIKUS PUTIH JANTAN (Rattus Norvegicus) DIABETES MELITUS YANG DI INDUKSI STREPTOZOTOCIN Simarmata, Hans Pangestu; Saragih, Reyini Namora L.; Pasaribu, Jelita Pebriani; Sitorus, Josua Panangian; Chiuman, Linda; Janice, Janice
Biospecies Vol. 14 No. 1 (2021): Januari 2021
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/biospecies.v14i1.11252

Diabetes mellitus is a disease problem in Indonesia due to the inability of the pancreas to produce insulin so the body's metabolic processes are disrupted. Platelet Rich Plasma is widely known to be a treatment in various fields of medicine because it contains many growth factors (GFs) which are useful for triggering growth, tissue, and cell regeneration. This study was conducted to determine the effectiveness of PRP at doses of 0.5, 1.0, and 1.5 ml/kg BW for improving lipid profiles. This study used an experimental method where PRP was made twice centrifugation, then divided into each treatment, each group was given twice a week for three weeks. The Shapiro-Wilk test was used for normally distributed data followed by the Kruskal-Wallis test followed by the analysis Mann-Whitney with a significant value of P <0.05, that is, there was an effect of PRP administration on improving levels of lipid profiles. The PRP dose of 0.5 ml/kg BW gave the effect of increasing the lipid profile except for HDL levels and a higher PRP dose was required to significantly increase HDL levels compared to the control group.Â Â

Clinical Functional Profile of the Hands of Patients with Rheumatoid Arthritis at Royal Prima Hospital Medan Coray Carolyn Ruth Pardede, Eifel; Alexander, Rico; Chiuman, Linda
International Journal of Science and Environment (IJSE) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara in Colaboration with www.stie-sampit.ac.id

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijse.v5i4.284

Rheumatoid arthritis (RA) is a chronic autoimmune disease that frequently causes progressive joint damage, particularly in the hands, resulting in impaired functional ability in daily activities. This study aims to describe the hand function of patients with rheumatoid arthritis based on age, gender, and family history at Royal Prima Hospital Medan. This research employed a descriptive quantitative design with a cross-sectional approach involving 55 respondents who met the inclusion criteria. Data were collected using a structured hand function questionnaire assessing right hand, left-hand, and bilateral hand function across various activities. Data analysis was conducted using univariate and bivariate descriptive methods through cross tabulation. The results showed that hand function impairment was most prominent in patients aged >40 years, who predominantly fell into the “poor” function category. Female respondents demonstrated a higher level of functional limitation compared to males. Meanwhile, a family history of RAcontributed as a predisposing factor but did not directly correlate with the severity of functional impairment. Patients with a family history tended to fall within the “moderate” category, while more severe impairment was observed among those without a family history. Older age and female gender are major factors associated with reduced hand function in RA patients, whereas family history serves as a predisposition rather than a determinant of severity.

Effect of Garlic Extract on Cholesterol and Glucose in High-Fat Diet STZ Induced Rats Veronica, Veronica; Girsang, Ermi; Chiuman, Linda; Puspita, Sunny
Eduvest - Journal of Universal Studies Vol. 6 No. 1 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i1.52663

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by elevated blood glucose levels and is linked to an increased risk of hypercholesterolemia. Garlic (Allium sativum Linn), which contains bioactive compounds such as saponins and flavonoids, has potential for managing these conditions. This study aimed to evaluate the effects of garlic extract on two parameters: blood cholesterol levels in Wistar rats fed a high-fat diet and blood glucose levels in rats induced with streptozotocin (STZ). A laboratory experimental post-test-only control group design was used. For cholesterol assessment, hypercholesterolemic rats were treated with garlic extract at doses of 0.05, 0.10, or 0.20 g/head/day, alongside negative and positive control groups. For glucose assessment, STZ-induced diabetic rats received garlic extract at 100, 250, or 500 mg/kgBW/day, with corresponding control groups. Garlic extract significantly reduced mean cholesterol levels in a dose-dependent manner (130.60 mg/dL, 121.80 mg/dL, and 112.00 mg/dL for 0.05, 0.10, and 0.20 g/head/day, respectively). In contrast, mean blood glucose levels showed a marginal decrease with higher doses (282.80 mg/dL, 271.20 mg/dL, and 269.27 mg/dL for 100, 250, and 500 mg/kgBW/day), but no statistically significant differences were observed among groups (P = 0.706, one-way ANOVA). These findings suggest that garlic extract exhibits a significant cholesterol-lowering effect in hypercholesterolemic rats but does not markedly reduce blood glucose levels in STZ-induced diabetic rats at the tested dosages.

Analysis Of Differences in Stress Levels of Nurses Working in Isolation and Non-Isolation Wards for Covid-19 In General Hospital Royal Prima Medan Stefenie; Ermi Girsang; Linda Chiuman; Sri Wahyuni Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Along with the escalating number of confirmed cases of COVID-19, it becomes a big demand for medical staff, in particular nurses, as the frontline in caring COVID-19 patients, this makes nurses’ stress levels to build up. So, this research aims to describe the factors that affect stress levels experienced by nurses during the pandemic COVID-19. The purpose of this study is to analyze the differences in stress levels of nurses working in isolation and non isolation wards for COVID 19 in General Hospital Royal Prima Medan. Type of research used in this research is quantitative research by using Cross Sectional approach. The results obtained from this research is that the majority of nurses in non isolation ward have stress levels that are still within normal limits with good performance and moderate workload, and the majority of nurses in isolation ward have a high level of stress with poor performance and a heavy workload. Workload (OR =5.21 95%CI 2.47-10.95; p=0.015), Performance (OR =2.60 95%CI 1.38-4.91; p=0.002), and Work Unit (OR =5.33 95%CI 2.65-10.75; p=0.029) significantly affect the sress level of nurses working at General Hospital Royal Prima Medan.

Effectiveness Of Incision Wound Healing Of Pandanus Amaryllifolius Roxb In Wistar Rats Putri, Muna Soraya; Girsang, Ermi; Chiuman, Linda; Ginting, Chrismis Novalinda
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

The incision is a condition of tissue discontinuity that is commonly encountered with the risk of prolonged healing time, imperfect wound healing, infection, etc. Assessment of the wound healing activity of the incision is the purpose of this research, which includes an examination of wound contraction, the thickness of collagen fibers, and the number of new blood vessels formation. In total, 25 rats will be divided into 5 test groups, each consisting of 5 rats; the control group (cream base treated), standard group (Povidone Iodine), followed by the treated group with 10%, 20%, and 30% pandan leaf extract ointment. The preliminary screening of phytochemical analysisshowed the presence of alkaloids, saponins, flavonoids, tannins, triterpenoids, and steroids and glycosides, with the total content of phenols and flavonoids from the ethanolic extract of Pandan Wangi is 20.95 GAE mg/gram extract, and 23.57 TAE mg/gram extract. Wound contraction examination result showed a significant difference between the treatment groups on day 16 and a sign the pairs of groups after being given the ointment with each concentration (p <0.05), especially in the group with 30% fragrant leaves extract and the standard group. Examination of new blood vessels showed a significant difference (p <0.05), especially with 30% of the leaves extract ointment. There was also a significant difference in collagen density in the group given pandanus ethanol ointment, especially at the 30% pandanus extract content against the group that was only given the ointment base. This research strongly suggests that the fragrant pandan leaf extract ointment is effective in healing incisional wounds and promises the potential for further studies on the pharmacological aspects.

Testing Antioxidant And Antibacterial Activity Of Andaliman Fruit (Zanthoxylum Acanthopodium Dc.) Ethanol Extract With Abts Method (2,2'-Azino-Bis(3-Ethylbenz-Thiazoline-6-Sulfonic Acid) And Minimum Resistant Concentration Agung Adha Witasa Dewana; Tan Suyono; Linda Chiuman; Sahna Ferdinand Ginting
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Antioxidants are chemical compounds that can donate one or more electrons to free radicals, so that these free radicals can be quenched. There are two sources of antioxidants, namely natural and synthetic antioxidants. Andaliman (Zanthoxylum acanthopodium DC.) is one of the many spice plants found in Toba Samosir and North Tapanuli Regencies, North Sumatra. Andaliman plants grow at an altitude of 1,500 m above sea level. Apart from North Sumatra. This research using method experimental research when collecting and processing andaliman fruit, making simplicia, making ethanol extracts and examining antioxidant activity tests using the ABTS free radical scavenging method (2,2'-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid) and antibacterial activity. using the minimum inhibitory concentration method. Testing the antioxidant activity of the ethanol extract of andaliman fruit with the ABTS method using a UV-VIS spectrophotometer with a wavelength of 734 nm. the regression equation (y = 0.4619 + 20.226) obtained an IC50 value of 64.4598 mg/mL which can be classified as a strong antioxidant activity. The results of the antibacterial activity test of the ethanol extract of the andaliman fruit showed that the extract had antibacterial activity in the moderate category at a concentration of 300 mg/ml with an inhibition zone of 10.

Test of Antioxidant And Antibacterial Activity of Ethanol Extract of Andaliman Fruit (Zanthoxylum Acanthopodium Dc.) With Dpph (1.1-Diphenyl-2-Picrylhydrazil) Trapping Method And Minimum Inhibitory Concentration Ira Syaputri; Ermi Girsang; Linda Chiuman
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

Utilization of bioavailability according to World Health Organization (WHO) records is very large, it is estimated that almost 80% of mankind, especially in developing countries, still use plants as medicinal ingredients to maintain their health (Nugraheni, 2007). Andaliman (Zanthoxylum acanthopodium DC.) which belongs to the Rutaceae tribe which is one of the plants known to the Batak community, is classified as a wild plant and is a typical plant of Province North Sumatra. The method used in this research is experimental research. The research included collecting and processing andaliman fruit, making simplicia, making ethanol extracts, and examining antioxidant activity tests using the DPPH free radical scavenging method (1,1-diphenyl-2-picrylhydrazil) and antibacterial activity using the minimum inhibitory concentration method. The results of the antibacterial activity test of the ethanolic extract of andaliman fruit showed that the extract had antibacterial activity in the moderate category at a concentration of 300 mg/ml with an inhibition zone of 10.17 mm for Staphylococcus aureus bacteria and a moderate category for Staphylococcus epidermidis bacteria with an inhibition zone of 10.80 mm. The ethanol extract of andaliman fruit can inhibit Staphylococcus aureus and Staphylococcus epidermidis, effective at a concentration of 300 mg/ml with inhibitory diameters of 10.17 mm and 10.80 mm, respectively.

An Effect Virgin Coconut Oil Oral And Topical On Volume Decrease Of Foot Edema Of Male Wistar Flows Induced By –Caragenan Dzil Fikri; Ermi Girsang; Ali Napiah Nasution; Linda Chiuman
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Virgin Coconut Oil(VCO) is virgin coconut oil that is made enzymatically. The content of saturated fatty acids and flavonoid compounds in VCO can be used as an anti-inflammatory drug. This study aims to determine the activity of VCO as an anti-inflammatory. Anti-inflammatory activity was tested using the method of calculating the percentage of inflammation inhibition in white rat paws induced by intraplantar 1% carrageenan solution. The decrease in edema in the rat's feet was measured using a plethysmometer for 360 minutes. The results showed that VCO at a dose of 0.4 ml/200 g BW and 0.8 ml/200 g BW gave anti-inflammatory activity with the percentage of inflammation inhibition of 64.34 ± 9.90 and 52.66 ± 8, respectively. 94. The anti-inflammatory activity of VCO at a dose of 0.4 ml/ 200 g BW and a dose of 0.

Changes In Gait, Balance and Comfort That Is Felt in The Use of Shoes with Height-Elevating Insole with A Height Of 5, 7 and 9 Cm Lawrence, Christopher; Novalinda, Chrismis; Chiuman, Linda; Girsang, Ermi
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 1 (2022): February 2023
Publisher : CV. Inara

The Use of shoes with height-elevating insole lately has been rife in the community. Use sol high this can affect the function of static and dynamic body, where physical changes in the body. As a result, generate a posture which is not stable, not balanced, and less comfortable when used in daily activities. Have many kinds of shoes with high soles with distinctions high pedestal the soles of shoes that allow the existence of different effects for the body. Objective, Prove the change of gait, balance and comfort in use of the shoe with a height-elevating the insole at the height of 5, 7, 9 cm. Material and Methods, experimental Research with pre and post test design. Subjects are men aged 20-22 years with a Body Mass Index (BMI) normal. Thirty people who are willing to follow the study and meet the inclusion and exclusion criteria were divided randomly into 3 groups, group a 5 cm, 7 cm and 9 cm, which respectively amounted to 10 people. Each group performed a walk test to test gait, one leg stands and tandemstand to test the balance with the barefoot/barefoot, shoes with height- elevating the insole with the same high. Results, the Results of this study show a change in gait and balance that are significant between barefoot and wearing shoes high soles (p=0.005). But the difference between the shoes with the height-elevating insole with a height of 5, 7 and 9 cm is not significant on the parameters of gait (p=0.329) but there is a change of balance in between shoes high soles 5, 7, 9 cm on the parameters of the balance (p=0.000). Conclusion, there are differences in the balance and there was no difference in gait on the use of the shoe’s height-elevating insole different (5, 7, 9 cm).

Co-Authors Adrian Adrian Adrian Adrian Afina, Lubna Agung Adha Witasa Dewana Akalili, Cory Cintia Alexander Simanjuntak Alexander, Rico AMALIA, TIARA Amir, Widya Pasca Andika Zayani Tambunan Anditha, Arie Tika Anggraeni, Wenti Arif, Maria Nisaul Aulia, Rumi Azah, Yunita Wannur Bagas Dwi Sanjaya Bangun, Chrismas Gideon Bangun, Primta Binarwan Halim Br Ginting, Lois Eprillia Bukit, Christin Debora Chairun, Ryeo Ramadhan Chintya Darma, Gladys Chiuman, Veranyca Claudia Tanamal Colin, Vito Coray Carolyn Ruth Pardede, Eifel Datitha Alodia Br Kaban, Karina DEWI SARTIKA Dhillon, Neha Amar Dika Suranda Dwi Puspitasari Dzil Fikri Edy Fachrial Erika Erika Ermi Girsang Fahlevy, Ridho Fazwiansyah Darlin Muniro Febriani Simanjuntak, Lorena Felix, Jesslyn Fentia, Lia Ferdinand, Sahna Fiska Maya Wardhani gan, claris cyntha deninta Ginting, Chirmis Novalinda Ginting, Chrismis Novalina Ginting, Chrismis Novalinda Ginting, Sahna Ferdinand Girsang, Ermi Gozali, Juliana Grandis, Lexandria Gusbakti Gusbakti Rusip hafizha, Shalli Haicha Pritama, Irza Halim, Angel Jonathane Halim, Michael Handayani, Rr. Anisa Siwianti hardiansyah siregar Harmileni Hasya, Muhammad Nawal Hestina Hidayatti, Mustika Ibnu, Syahroni Iksen, Iksen Indriani, Vidya Intan Hasibuan, Febria Nurul Ira Syaputri Irwan Irwan irza Haicha Pratama Iskandar, Ari Rahman Janice Janice Kosasih, Michaela Kotsasi, Fransisca Krishna, Priyanka Kurniawan, Gracella Verren Lawrence, Christopher Leony, Catherine Levinna, Levinna Lie, Veronica Liena, Liena lister , Clarissa Lister, Gilbert Lumbantobing, Christina J. R. Esmaralda Lumbantobing, Christina J.R Esmaralda Lumbantobing, Christina J.R.E. Marfitania, Taranipa Maswarni Mawarni, Evi Michael Michael MICHELLE HENDRIANI DJUANG Miranda Winda Sari Sitorus Mukti, Ade Indra Nadapdap, Thomson Nasution, Ali Napiah Nasution, Atika Rimalda Nasution, Isna Gita Amalia Novalinda, Chrismis Nurlaela, Lia Olivia Laurent Ong, Gabriella Fransisca Ongko, Nicolas Xavier Pardianto, Gede Pasaribu, Jelita Pebriani Patriyuni, Tri Permata Khaira, Azzuhra Pinem, Sabriela Br Puspita, Sunny Putri, Muna Soraya Rajagukguk, Samuel Joshua Hamonangan Tua Rambe, Natasya Septiana Razoki, Razoki Rizki, Kartika Sari Sagala, Agasy Gideon Admiral Sahna Ferdinand Ginting Saragih, Chanli Saragih, Reyini Namora L. Sebayang, Dwi Putri Agita Sembiring, Mahral Effendi Sihombing, Bungaran Simarmata, Hans Pangestu Siti Hardianti, Siti Sitorus, Josua Panangian Soekardi, Adi Stanliko, Stanliko Stefenie Suandy, Suandy Suhartomi Sulistijanto, Eddy Suyono, Tan Syahputra, Hariyadi Dharmawan Sylvana, Dhini Tambunan, Ridhona Tan Suyono Tanamal, Claudia Tandiono, Michelle Tarigan, Elviyanti Tarigan, Setia Budi Tengku Rachmi Hidayani, Tengku Rachmi Tia Triyanti Tjendera, Mariaman Utami, Sherlinda Putri Utomo, Wilbert Waldo Varerina, Ria Br Perangin-angin Vera Estefania Kaban vera vera, vera VERONICA VERONICA Virgoh, Livia WAHYU WIDOWATI Wardhani, Fiska Maya Wijaya, Johanna Fransiska Wijaya, Linda Leonando Winda Sari Yosefa, Stephanie Renata Yuliansyah, Jeri Yulita, Emi Yusmaini, Yusmaini Zendrato, Ronauli Muliani

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