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Siti Rohani
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Journal : biomedical journal of indonesia

 1 
The Potential of Rosella (Hibiscus sabdariffa L.) for Diabetes Mellitus Model Rats: Histopathological Focus on Pancreatic Organ Putria, Sinta Julia Liona; Rohani, Siti; Suarni, Ertati; Astri, Yesi; Mundijo, Trisnawati
Biomedical Journal of Indonesia Vol. 11 No. 1 (2025): Vol 11, No 1, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v11i1.236

Abstract

Introduction. Ethanolic extract of rosella flowers (Hibiscus sabdariffa L.) contains secondary metabolite compounds: flavonoids, alkaloids, saponins, and tannins. This study aims to determine whether the ethanol extract of rosella flowers has the potential to regenerate pancreatic β cells in white rats (Rattus norvegicus) with alloxan-induced diabetes mellitus models.  Methods. The type of research used was an in vivo laboratory experimental study with a true experimental design. The experimental animals used as test objects in this study were male rats (Rattus norvegicus L.), weighing 100-110 grams. The test objects were 30 rats, divided into 6 groups randomly, each containing 5 rats, the groups consisted of K (N), K (-), K (+), P (1), P (2), and P (3). The level of histopathological damage to the pancreas was observed with HE staining at 400x magnification, using binocular light microscope type CX23 and BX51. Results. The study showed that the ethanol preparation of rosella flower extract at a dose of 1500 mg/kgBW and 3000 mg/kgBW BB was effective in regenerating pancreatic β cells with a damage value of 0 and at a dose of 750 mg/kgBW with a damage value of 2 did not provide a maximum regeneration effect on pancreatic β cells in male white rats induced by alloxan. Conclusion. The results of this research show that the ethanol extract of rosella flowers has an influence on the regeneration of pancreatic β cells so that it can be used for supportive treatment in the management of diabetes mellitus.
Shared Mattresses, Combs, and Residential Sanitation Associated with Pediculosis Capitis in Orphanages Istanta, Qoonitah Salsabiil Putri; Rohani, Siti; Anwar, Chairil
Biomedical Journal of Indonesia Vol. 12 No. 2 (2026): Vol 12, No 2, 2026, In Press
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v12i2.325

Abstract

Introduction. Head lice infestation (pediculosis capitis) continues to be a widespread health issue among children, especially in orphanages. Pediculosis capitis often occurs due to sharing personal items and poor residential sanitation conditions. Methods. This study applied an observational analytic design using a cross-sectional approach, conducted across nine orphanages in South Sumatra Province. Independent variables included sharing personal items and residential sanitation factors such as occupancy density, ventilation, lighting, temperature, and humidity, while the dependent variable was pediculosis capitis occurrence. Results. Pediculosis capitis prevalence reached 37.7%. Sharing mattresses (p = 0.038) and combs (p = 0.016) showed a significant association with pediculosis capitis, while sharing bed sheets, blankets, pillows, towels, headscarves, prayer garments, and caps was not significantly associated. In terms of residential sanitation, occupancy density (p = 0.002), ventilation (p < 0.001), and lighting (p < 0.001) were significantly related to the occurrence of pediculosis capitis. Meanwhile, temperature (p = 0.678) and humidity (p = 0.585) did not show a significant relationship. Conclusion. Pediculosis capitis occurrence is linked to sharing certain personal items and various residential sanitation factors.
Co-Authors A.A. Ketut Agung Cahyawan W A.P, Nabila Najwa Abas, Muh. Abdullah Abdullah Ade Suyani Agung Prasetyo NW Agustina, Hiqma Nur Ahmad Juanda Akmal Indra Al Farizi, Ahmad Bayu Alfiqri, M.pr Alhadiansyah Alifiyanti Muharramah Alkadrie, Zata Yumni Martha Amalia, Siska Amelia Putri, Ira Amiruddin Analisti, Dea Anggita, Anggita Anggraini, Wieke Anjar, Agus Any Setyaningsih Any Setyaningsih, Any Arif, M. Syaikul Armeli Zulfa, Mahda Asikin, Uti Astuti Astuti - AYU WULANDARI Bagus Pria Alwadipa Budi Utama, Budi Chairani, Liza Chairil Anwar Custer, Johny Deinsyah, Putri DESI KUMALA SARI Desi Kumalasari Dewani, Shakira Listi Putri Dewi, Anita Sartika Dhirah, Ulfa Husna Dikdik Mulyadi Dimas Wahyu Wibowo Disyon, Huta Driana Leniwati Dwi Maryanti Dwiryanti, Rizki Efriyanti, Liza Eka Tri Wulandari, Eka Tri Elisatris Gultom Enny Mulyatsih Erlisnawati Erlisnawati Evi Purwanti Evi Silvana Muchsinati Fadillah, Yudhi Fahmi Dwi Mawardi Faisal Ananda Farulyan, Neska Fatkhurrahman, Nandana Rizqi Andhika Fauzi Fauzi Fhatirisq, Incik Erick Fikron Nisa’, Zainab Firdaus Firdaus ghazali, Achmad Al Gunawan, Arief Hadi Pranoto Hak, Pendais Hamid Mukhlis Hellen Febriyanti Helmida, Santi Hermi Yanzi Hidayat, Nazwin Hidayati - Hisham, Muhammad Rivaldy Hopeman, Teofilus Ardian Humaidi, Irfan Ahmad I Wayan Gede Astawa Karang I Wayan Nurjaya Ida Ayu Putu Sri Widnyani Ika Avrilina Haryono Ika Yulia Sari Ilham Hudi Aim Abdulkarim Kokom Komalasari, Ilham Hudi Aim Abdulkarim Indah, Komalasari Indrianti, Titien Indriyani Indriyani Ipmawan Muhammad Iqbal Irawan Suntoro Istanta, Qoonitah Salsabiil Putri Istifaiyah, Alda Imroatul Jannah, Umi Nuril Patul Jonathan Jonathan Juli Yanti, Juli Julia, Sinta Junita Junita Juwita Desri Ayu Kalkhove, Bella Ariesta Karlina, Dina Kasman Kesuma, Putri Kesuma, Putri Zalika Laila Mardiah Khairia, Ira Khairuddin - Khairunisa, Siti Kharanza, Yoenua Khusuma Sapitri, Lina Kirana, Rika Dani Kurniawan, Hikmal Kurniawaty, Dewi Laila Rahmawati Laila, Henni Latipah Hanum Batubara Lestari, Vika Linda Puspita LINDA PUSPITASARI - A11111054, LINDA PUSPITASARI Lisman, Muhammad Listiana, Endang Lutfi, M.Haddad Lutfiah Hafidzah M. Hufron M. Yogi Riyantama Isjoni Mahmud Alpusari Malau, Lily Gabriel Mareza Yolanda Umar Marhini, La Ode Martha, Fadhil Rizki Marzuki Noor Maulidia, Shafira Zaky Maulidiyah, Fitrotul Melianti, Agnes Milla Marlina Assegaf Mimi Viviyana Mitayani Purwoko, Mitayani Moh. Anshori Aris Widya Mohammad Rizal Mon, Muhammad Donal Muhaimin Muhamad Aji Purwanto Muhammad Arif Batubara Muhammad Arman Muhammad Rusdi dan Afritha Amelia - Muhammad Umar Mukmilah Yuningsih, Lela Mundijo, Trisnawati Mutaqin, M. Hidayat Mutiara, Nabella Nabila, Amelia Nadia Hanayeen Nainggolan, Ferdinand Nasution, Saidah Tunnur Nelson, Alden Nila Karimah Nita Maya Valiantien Nopi Anggista Putri Novalia Widiya Ningrum Novebri Novebri Nufus, Wealthy Sakinati Nugerahaeni, Sucia Dwi Nugrahaningtyas Fatma Anyassari Nurazizah, Amalia Siti Nurhaliza, Nurhaliza Nurhaya, Nurhaya Nurleni, Nurleni Nurrosidha, Yossy Nursantri Yanti Nurul Fahmi Nurulatifah, Nurulatifah Oktariza, Rury Tiara Oktavianti, Rizky Patriani, Ira Paulus, Vitalius Prabowo, Muhammad Ilham Putro Prameswarie, Thia Primadevi, Inggit Psiari Kusuma Wardani Putra R, Rahmadsyah Putra, Edy Yulianto Putra, Herman Eka Putri Deinsyah Putri, Arsy Putria, Sinta Julia Liona Qhadafi, Muamar Rachmawati Rachmawati Rahma Yenni Rahmadani, Novi Rahmah, Yunita Raisha, Zafira Ananda Ramayanti, Indri Ramdhan Ratih Anggraini, Ratih Rayaramadhana, Suci Retnawati, Heni Rezky Pramana Putra Ridhayati Farid Rina Kartikasari, Rina Rindi Genesa Hatika Rini Wahyuni Rini Wahyuni Rio, Muhammad Ririn Setyowati Riska Safitri, Riska Riska Siregar Riski Khairani Rizki Yeni Wulandari Roshid, Mohammod Moninoor Saputra, Dika Saputra, M. Dimas Saputra, Rio Saraswati, Nia Ayu Sarera, Domitila Patrica Sari Wahyuni, Lily Sudhartio, Sari, Devina Puspita Sekarsari, Putri Seltina, Indah Septika Yani Veronica Setyawan, Agustinus Shea, Sun Yiek Silvia Rita, Silvia Siregar, Rumiah Siti Aisah Siti Komariah Siti Maesaroh Siti Rahmawati Siti Rohani.,SST.,Bdn.,M.Kes Sri Achadi Nugraheni Sri Haryanto Sri Rahayu, Mariya Suarni, Ertati Suasono, eddy Sucahyo Masan Al Wahid Suci Irawati Sugeng Hariyanto Susi Irianti Syahrilfuddin Syahrilfuddin, Syahrilfuddin Syarah, Swari Tan, Cellina Tan, Roby Taufik Taufik Tiza Yaniza Tri Inda Fadhila Rahma Trisnawati Trisnawati Umi Aisyiyah Usrah, Cut Rizka Al Vina Pramayastri Wahab, Fathurrahaman Wahiddin, Shafiyyah Widiyastuti, Sri Wisnu Yuwono Wuysang, Julia Magdalena Yaniza, Tiza Yanti Rosita Yeni Kurniawati Sumantri Yeni, Rahma Yesi Astri Yesi Astri Yogi Andhi Lestari Yona Desni Sagita Yona Desni Sagita, Yona Desni Yuli Naulita Yulianti, Katarina Yulinda Hervilia Yuni Sulistiawati Yunita Anggriani Zaidi Bin Othman Zakir, Supratman Zariul Antosa Zawawi, Azlyn Ahmad Zilda, Malika ZULFAH Zulfah Zulfah