E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri
Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran Universitas Indonesia/ Rumah Sakit Dr. Cipto Mangunkusumo

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Nilai Diagnostik Rerata Tekanan Darah Pre dan Post Hemodialisis pada Pasien yang Menjalani Hemodialisis Kronik Purba, Ferry Tigor P.; Siregar, Parlindungan; Nainggolan, Ginova; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 1, No. 2
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Pendahuluan. Penyebab utama morbiditas dan mortalitas pada pasien PGK (penyakit ginjal kronik) yang menjalani HD (hemodialisis) kronik adalah penyakit kardiovaskuler. Faktor utama penyebab kejadian kardiovaskuler pada pasien PGK yang menjalani HD adalah hipertensi. Diagnosis hipertensi pada pasien PGK yang menjalani HD tidaklah mudah. Hal ini dikarenakan adanya efek retensi cairan, office hypertension, dan proses ultrafiltrasi setelah HD. Baku emas diagnosis hipertensi pada pasien HD adalah pemeriksaan tekanan darah interdialitik dengan menggunakan alat ambulatory blood pressure monitoring (ABPM). Namun alat ini memiliki banyak kendala dalam pemeriksaannya. Studi sebelumnya yang meneliti tekanan darah pre dan post dialisis dibandingkan dengan tekanan darah ABPM memberikan hasil yang masih kontroversial. Penelitian ini bertujuan untuk mengetahui korelasi dan nilai diagnostik rerata tekanan darah pre dan post hemodialisis dengan baku emas tekanan darah interdialisis yang diukur dengan metode ABPM. Metode. Dilakukan studi diagnostik dan uji korelasi dengan desain penelitian potong lintang pada tiga puluh lima pasien dewasa dengan penyakit ginjal kronik yang menjalani hemodialisis kronik. Pasien yang memenuhi kriteria penelitian dilakukan pengukuran ABPM selama 24 jam dan tekanan darah saat pre dan post dialisis. Hasil. Uji korelasi Pearson menunjukkan korelasi rerata TD sistolik pre-post dialisis dan sistolik ABPM sebesar r = 0,669 dan p= 0,000 dengan AUC sebesar 84,4% (95% IK, 71,5% - 97,3%) dengan p = 0,001 serta nilai sensitivitas 82,14%, spesifisitas 71.43%, nilai duga positif 92%, dan nilai duga negatif 50%. Uji korelasi Pearson mendapatkan korelasi antara rerata TD diastolik prepost dialisis dan diastolik ABPM sebesar r = 0,359 dan p = 0,034 dengan AUC sebesar 67,6 % (95% IK, 49,3 % - 86,0%) dengan p= 0,075 serta nilai sensitivitas 82,14%, spesifisitas 85,71%, nilai duga positif 95,83%, dan nilai duga negatif 54,55%. Simpulan. Rerata tekanan darah sistolik pre-post hemodialisis dapat digunakan untuk diagnosis hipertensi pada pasien penyakit ginjal kronik yang menjalani hemodialisis kronik.
Perbedaan Serotonin Plasma dan Kortisol Saliva terhadap Gejala Depresi pada Pasien Pasca Sindrom Koroner Akut Firmansyah, Irman; Shatri, Hamzah; Putranto, Rudi; Ardani, Yanuar; Ginanjar, Eka; koesnoe, sukamto; Rizka, Aulia; Isbagio, Harry; Yunir, Em
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 3
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Introduction. Psychological disorders are closely associated with hormonal factors, including cortisol and serotonin. In patients with acute coronary syndrome (ACS), autonomic dysfunction and dysregulation of the hypothalamic-pituitaryadrenal (HPA) axis can occur, leading to an increase in cortisol levels that may worsen the prognosis of ACS patients. Therefore, it is important to understand the hormonal impact, namely cortisol and serotonin levels, on depressive symptoms, which will be examined in this study. Methods. This was a cross-sectional study to determine the impact of cortisol and serotonin in the incidence of depression in post-treatment ACS patients at the ICCU RSUPN dr. Cipto Mangunkusumo, Jakarta. Data collection from patients meeting the inclusion criteria was carried out 10-14 days post-treatment through interviews, HADS questionnaire completion, physical examinations, and laboratory tests. The Mann-Whitney test was used to examine the differences between serotonin and salivary cortisol levels in patients with and without depression. Results. Among the 73 ACS patients included in this study, the average age was 57.53 (9.97) years, with 68.5% was male. Posttreatment depression was observed in 15.1% of subjects. The median serotonin levels were lower in patients with depression [175 (147 – 227.64) ng/mL vs. 189.31 (152.87-235.44) ng/mL], while cortisol levels were higher in patients with depression [3.09 (1.46-6.26) ng/mL vs. 2.15 (0.92-3.91) ng/mL]. However, the statistical analysis showed no significant differences between plasma serotonin and depression (p=0.482) or saliva cortisol and depression (p=0.275). Conclusions. There were no significant differences in cortisol and serotonin levels concerning depressive symptoms among post-acute coronary syndrome patients. Nevertheless, this study holds clinical importance due to the observed lower plasma serotonin levels and higher saliva cortisol levels in ACS patients with depression.
Modifikasi Skor TIMI sebagai Model Prediksi Mortalitas 30 Hari Pasien STEMI Muda Mansur, M. Tasrif; Yamin, Muhammad; Rusdi, Lusiani; Abdullah, Murdani; Karim, Birry; Rumende, Cleopas Martin; Marbun, Maruhum Bonar H.; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 4
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Introduction. Cardiovascular disease is a leading cause of death worldwide. Three-quarters of these deaths occur in lowand middle-income countries among individuals in their productive years. ST-segment elevation myocardial infarction (STEMI) is a dangerous manifestation of coronary artery disease (CAD) and can lead to sudden death. Smoking and a family history of early CAD are major risk factors for STEMI cases. However, their role in any risk stratification system for patients has not been clearly established. The most widely used score in assessing the prognosis of STEMI patients is the TIMI score, but its accuracy in the young patient population is still unknown. The objectives of this study were to determine the proportion of mortality in young STEMI patients at RSCM, validate the TIMI score in young patients, and develop a risk stratification system for young STEMI patients. Methods. This research is a retrospective cohort study using medical record data from the Dr. Cipto Mangunkusumo National General Hospital (RSCM) on patients aged ≤50 years who were treated for ST-elevation myocardial infarction (STEMI) from 2018 to 2022. Univariate analysis was conducted to obtain subject characteristics and the 30-day mortality proportion of young STEMI patients. Bivariate Cox regression analysis was performed to examine the relationship between smoking and a family history of early coronary artery disease (CAD) with 30-day mortality. The TIMI score was validated in the study subjects of young patients. Multivariate analysis was conducted to obtain a new prediction model, and the model’s discriminatory performance was assessed using the area under the ROC curve (AUC), and model calibration was modified using the Hosmer-Lemeshow test. Results. A total of 164 study subjects were included. There were 107 patients (65.2%) with a smoking risk factor, while 39 patients (23.9%) had a family history of early CAD. The proportion of 30-day mortality among young patients was 7.9% (13 individuals). Statistical analysis showed that there was no correlation between 30-day mortality in young STEMI patients and a history of smoking (HR 0.0441 (95% CI 0.148-1.312)) or a family history of early CAD (HR 0.567 (95% CI 0.126- 2.559)). The TIMI score showed good predictive ability for 30-day mortality in young STEMI patients, with an AUC value of 0.836 (95% CI 0.717- 0.956). The combination of the TIMI score with the smoking history variable demonstrated good discriminatory performance in predicting 30-day mortality among young STEMI patients, with an AUC value of 0.875. However, when comparing the AUC values between the TIMI score and the TIMI score with the addition of the smoking history factor, no significant increase in accuracy was observed (p-value=0.215). Conclusions. The TIMI score demonstrates good discrimination and calibration in predicting 30-day mortality among young STEMI patients. The TIMI score, when combined with the smoking history factor, shows improved discriminatory performance and calibration in predicting 30-day mortality among young STEMI patients compared to the pure TIMI score but does not significantly enhance the accuracy.
Evaluasi Pengukuran Kekakuan Limpa dalam Memprediksi Perdarahan Varises Esofagus Berulang pada Pasien Sirosis Hati Tahir, Andi Cahaya; Kurniawan, Juferdy; Simadibrata, Marcellus; Rizka, Aulia; Shatri, Hamzah; Lesmana, Cosmas Rinaldi A.; Mulansari, Nadia Ayu
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 1
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Introduction. Esophageal variceal bleeding is one of the complications caused by an increase in pressure within the portal vein blood vessels. The gold standard examination for portal pressure is the hepatic venous pressure gradient (HVPG), but HVPG examination is invasive, involving transjugular catheterization of the hepatic vein. Currently, non-invasive methods for measuring portal hypertension are being developed to predict esophageal varices and esophageal variceal bleeding using spleen stiffness measurements. This study aimed to evaluate the accuracy of spleen stiffness measurement in predicting recurrent esophageal variceal bleeding in patients with liver cirrhosis. Methods. This study used a retrospective cohort design with secondary data sourced from medical records at Cipto Mangunkusumo Hospital. Spleen stiffness assessment was conducted using the vibration controlled transient elastography (VCTE) spleen-dedicated stiffness measurement (FibroScan®, Echosens, France) with a frequency of 100Hz. After six weeks post-first esophageal variceal bleeding in liver cirrhosis patients, an evaluation of recurrent esophageal variceal bleeding was performed. The collected data were analyzed using SPSS 26. The ability of spleen stiffness measurement to predict recurrent esophageal variceal bleeding was assessed by evaluating the AUROC (area under the curve of receiver operating characteristic) curve. Results. A total of 102 liver cirrhosis patients who experienced first-time esophageal variceal bleeding were included in the study. Recurrent esophageal variceal bleeding was found in 23/102 (22.5%) liver cirrhosis patients. There was a significant difference in spleen stiffness values between the two groups, with higher values in the group of patients with recurrent esophageal variceal bleeding (90.9 kPa (IQR: 86.5 – 96.2) vs. 59.3 kPa (IQR: 45.2 – 74.3), p < 0.001). The AUC value of spleen stiffness for predicting recurrent esophageal variceal bleeding provided good predictability, with an AUC value of 0.898 (95% CI 0.808 – 0.988), p < 0.001. The cut-off value of spleen stiffness at 70 kPa yielded a sensitivity of 87% and specificity of 65% in predicting recurrent esophageal variceal bleeding. Conclusion. Spleen stiffness measurement can be beneficial as an evaluation method to assess the likelihood of recurrent esophageal variceal bleeding in patients with liver cirrhosis at the 6th week after the first bleeding episode.
Faktor-faktor yang Berhubungan dengan Kualitas Tidur Pasien dengan Lupus Eritematosus Sistemik Andru, Gestana; Widhani, Alvina; Putranto, Rudi; Mansjoer, Arif; Shatri, Hamzah
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 2
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Introduction. Sleep disturbances are often found among Systemic Lupus Erythematosus (SLE) patients. Poor sleep may cause low quality of life. Study about sleep quality among SLE patients and related factors in Indonesia is scarce. This study aimed to know factors related to poor sleep quality among SLE patients. Methods. This cross-sectional study was conducted among SLE patients at Cipto Mangunkusumo Hospital Jakarta Indonesia. Sleep quality was assessed by Pittsburgh Sleep Quality Index (PSQI), with global PSQI score >5 indicates poor sleep quality. Factors evaluated were symptoms of depression and anxiety by Hospital Anxiety Depression Scale (HADS), pain by Visual Analogue Scale (VAS), Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K), autonomic dysfunction by Low Frequency/High Frequency (LF/HF) ratio from Heart Rate Variability (HRV), and high sensitivity C-Reactive Protein (hs-CRP) level. Bivariate analysis was done by Chi Square or Fisher’s test. Multivariate analysis was done by logistic regression, p value <0.05 was considered statistically significant. Results. Total of 166 SLE patients were included. Mean age was 32.7 years old with the majority in age group of 21-30 years old and female. Poor sleep quality in SLE patients was found in 82.5% of subjects. Symptoms of depression were significantly associated with poor sleep quality in SLE patients, especially sleep efficiency. Anxiety was associated with subjective month- and week-long sleep quality, sleep disturbances, and sleep medication usage. Musculoskeletal component of the SLEDAI-2K was associated with month- and week-long sleep quality, sleep latency, and daytime dysfunction. Hematologic involvement was associated with daytime dysfunction, whereas mucocutaneous involvement was associated with sleep disturbances. Conclusions. Symptoms of depression were significantly associated with poor sleep quality in SLE patients, especially sleep efficiency. Anxiety was associated with subjective month- and week-long sleep quality, sleep disturbances, and sleep medication usage.
Spleen and Liver Stiffness as Noninvasive Predictors of Varices in HBV Cirrhosis Siahaan, Billy Stinggo; Kurniawan, Juferdy; Simadibrata, Marcellus; Rizka, Aulia; Sanityoso, Andri; Rumende, Cleopas Martin; Rachman, Andhika; Shatri, Hamzah
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 2 (2023): VOLUME 24, NUMBER 2, August, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2422023137-142

Abstract

Background: Esophageal varices (EV) are the most frequent complication of portal hypertension in patients with liver cirrhosis. Due to many reasons, esophagogastroduodenoscopy remains impractical for routine surveillance in everyday practice. Hence, ongoing studies into reliable non-invasive test for predicting EV are still important.Methods: A total of 71 patients with liver cirrhosis due to hepatitis B who underwent endoscopy, spleen stiffness measurement (SSM), and liver stiffness measurement (LSM) between January and April 2023 were enrolled in this study. Diagnostic applicability was assessed using the area under the receiver-operator curve (AUC) to measure and compare the performance of each measurement and combination for predicting EV, as well as to obtain the corresponding optimal prediction value.Results: This study included 71 patients with liver cirrhosis. Among them, 74.6% (53 patients) were classified as Child-Pugh A, 22.5% (16 patients) as Child-Pugh B, and 2.8% (2 patients) as Child-Pugh C. The prevalence of esophageal varices (EV) within the cohort was 71.8%. This study showed that SSM with a cut-off of 38.8 kPa had AUC 0.867 (95% CI: 0.774–0.960) (sensitivity 78.4%, specificity 80%), and LSM with a cut-off of 10.55 kPa had AUC 0.822 (95% CI: 0.701–0.943) (sensitivity 88.2%, specificity 65%).Conclusion: Spleen and liver stiffness measurements demonstrate good performance in predicting EV in patients with liver cirrhosis caused by hepatitis B.
Selective Serotonin Reuptake Inhibitors and Risk of Gastrointesinal Bleeding In Dyspepsia: An Evidence-Based Case Report Shatri, Hamzah; Zulkifly, Steven; Putranto, Rudi; Makmun, Dadang; Fauzi, Achmad; Maulahela, Hasan; Faisal, Edward; Irvianita, Vinandia; Ardani, Yanuar
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 2 (2023): VOLUME 24, NUMBER 2, August, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2422023182-191

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Aim: This evidence-based case report aims to provide the latest evidence about the risk of gastrointesinal (GI) bleeding in selective serotonin reuptake inhibitor (SSRI) users with dyspepsia.Method: The literature search was conducted in four major electronic databases (PubMed, Cochrane, Scopus, ProQuest). The selected articles were sorted through screening abstract based on the inclusion and exclusion criteria. Critical appraisal was performed by using validated critical appraisal tool.Results: Of 247 records from extensive literature searching, three eligible studies (one randomized clinical trial and two cohort studies) were obtained to answer the clinical question. All studies showed SSRIs did not increase the risk of GI bleeding in patients with functional dyspepsia and peptic ulcer. However, the adverse event of SSRIs might be under-reported.Conclusion: According to the evidence, the risk of GI bleeding in SSRIs users with dyspepsia is still unclear. Larger size of sample of controlled trial study is recommended to be conducted to calculate the precise risk of GI bleeding in SSRI users with dyspepsia.
Sarkopenia sebagai Faktor Risiko Varises Esofagus Risiko Tinggi berdasarkan Stratifikasi Child-Pugh Pasien Sirosis Hati Sepmeitutu, Iwandheny; Kurniawan, Juferdy; Maulahela, Hasan; Rinaldi, Ikhwan; Shatri, Hamzah; Pramana, Triyanta Yuli; Makmun, Dadang; Lesmana, Cosmas Rinaldi A; Hidayat, Rudy; Laksmi, Purwita Wijaya; Sunardi, Diana
Jurnal Penyakit Dalam Indonesia
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Background The high prevalence of sarcopenia in chronic liver disease negatively impacts the quality of life and increases the risk of various complications of cirrhosis, one of which is the development of esophageal varices. The aim of this study was to determine the prevalence of sarcopenia in cirrhosis patients based on the severity of liver cirrhosis and to explore the association of sarcopenia with high-risk esophageal varices stratified by Child-Pugh. Methods This observational cross-sectional study involved patients with liver cirrhosis at Cipto Mangunkusumo Hospital between January and September 2023. Sarcopenia was defined as a reduction in muscle mass accompanied by decreased grip strength or walking speed, according to the AWGS 2019 criteria (Asian Working Group for Sarcopenia). Multivariate logistic regression analysis was conducted to evaluate the association between sarcopenia and high-risk esophageal varices. Results A total of 155 patients with liver cirrhosis were included in this study. The majority of liver cirrhosis patients were males, with hepatitis B being the most commonly found etiology. The prevalence of sarcopenia was found in 40.0% of Child-Pugh A patients, 53.8% of Child-Pugh B patients, and 50.0% of Child-Pugh C patients with a p-value of 0.411. The high-risk of esophageal varices was found more frequently in Child-Pugh B (53.8%) and Child-Pugh C (50.0%) compared to Child-Pugh A (25.6%) with a p-value of 0.013. Bivariate analysis showed that the presence of sarcopenia in liver cirrhosis patients has a statistically significant association with an increased risk of high-risk esophageal varices, especially in the Child-Pugh B and C subgroups of liver cirrhosis patients (OR = 7.50 (95% CI: 1.48 – 37.91, p<0.030)). However, no association was found between sarcopenia and high-risk esophageal varices in the Child-Pugh A subgroup (OR = 1.46 (95% CI: 0.65 – 3.29, p<0.477)). Conclusion Sarcopenia significantly increases the risk of high-risk esophageal varices in liver cirrhosis, especially in those with Child-Pugh B and C classification.
Psycho-Neuro-Autonomic Aspect of Burnout Syndrome: A Literature Review Oliviera, Ivona; Ardani, Yanuar; Shatri, Hamzah
International Journal of Cell and Biomedical Science Vol 2 No 6 (2023)
Publisher : Stem Cell and Cancer Research (SCCR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59278/cbs.v2i6.40

Abstract

Background: Burnout syndrome are symptoms resulting from stress due to burden and stressors of high workload, as seen in health workers. Burnout syndrome can trigger psychological and physiological disorders, mainly related to the autonomic nervous system and the Hypothalamus-Hypophysis Axis pathway. Psychological disorders could be assessed using Maslach Burnout Inventory (MBI), while physiological disorders of the neuro-autonomic imbalance could be assessed using Heart Rate Variability (HRV). Aim: To study about the psycho-neurological aspect of burnout syndrome. Methods: A systematic literature review using the PRISMA method, through four stages, namely identification, screening, feasibility, and accepted results. Results: Literature search was performed using PubMed and Google Scholar databases. Seven articles fulfilled the inclusion criteria. Five out of seven articles showed association between HRV and burnout score, while two articles showed no association between HRV and burnout score. Discussion: In the presence of stress, the autonomic nervous system activates the amygdala and hypothalamus, which subsequently triggers response from the adrenal gland to produce noradrenaline, which in turn affects the autonomic nervous system. A low HRV signifies inflexibility of the sympathetic and parasympathetic nervous system. Contradicting results may be caused by difference in sample and HRV confounding factors such as difference of physical activity, exercise, underlying disease, medication. Conclusion: There is an association between burnout score and HRV, which implies the presence of neuro-autonomic dysfunction in burnout patients. Further research is needed to rule out confounding factors.
Efektivitas Vaksin COVID-19 mRNA Booster Kedua pada Tenaga Kesehatan di Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo dan Faktor yang Memengaruhinya Lubis, Siti Taqwa Fitria; Koesnoe, Sukamto; Yunihastuti, Evy; Shatri, Hamzah; Karjadi, Teguh Harjono; Harimurti, Kuntjoro; Pitoyo, Ceva Wicaksono; Yunir, Em
Jurnal Penyakit Dalam Indonesia
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Introduction. The emergence of the Omicron variant during the pandemic had an impact on the effectiveness of the COVID-19 vaccine. The spread of Omicron increased rapidly even in populations that had been vaccinated with booster doses, causing a high incidence of infection. This study aimed to determine the effectiveness and factors related to the effectiveness of the second mRNA booster vaccine as well as antibody levels after the second mRNA booster vaccine in healthcare workers at Cipto Mangunkusumo National General Hospital. Methods. This study used a cohort design. Total sampling of 271 healthcare workers were obtained from previous research and continued with consecutive sampling. Selected subjects were interviewed, and blood samples were taken to measure IgG sRBD antibody levels. The effectiveness of the vaccine was calculated, and bivariate and multivariate analysis was carried out to assess the factors that influenced the effectiveness of the second mRNA booster vaccine. Results. A total of 9 subjects (5.6%) were infected with COVID-19 in the second booster vaccine group and 11 subjects (9.7%) in the first vaccine group. The effectiveness of the vaccine against COVID-19 infection was 42% (CI 95% -37 – 75%), p = 0,215. Age, gender, hypertension, type 2 DM, obesity, smoking, and COVID-19 infection before booster have no relationship to the effectiveness of the second booster mRNA vaccine. In 48 subjects who had their antibody levels checked during the first and second boosters, there was an increase from 4,743 AU/ml (IQR 6,053.3) to 8,532 AU/ml (IQR 8,040.3). Conclusions. The effectiveness of the second mRNA booster vaccine against COVID-19 infection in healthcare workers was 42%. There were no factors related to the effectiveness of the second mRNA booster vaccine. The sRBD antibody levels after the second booster vaccine were higher than the first booster vaccine.
Co-Authors -, Arles - -, Darmadi Achmad Fauzi Adhiatma, Kresna Aditama, Humala Prika Aditya Wardhana Adityo Susilo, Adityo Adli, Mizanul Agung, Ratih Arianita Agus Siswanto Agus Sudiro Waspodo Agustinus, Taolin Ahadini, Putri Aliya Aida Lydia Alexander, Reinaldo Ali Sakti Ali Sakti, Ali Alvina Widhani, Alvina Andhika Rachman Andri Sanityoso Andru, Gestana Anggono, Rendi F. Angraeni, Sri Anwar, Bariani Ardani, Yanuar Ari Fahrial Syam Arif Mansjoer Arif Sejati Aryadi Kurniawan Aryadi Kurniawan Asir, Taufik Rizkian Atmakusumah, Tubagus Djumhana Aulia Rizka, Aulia Azri Nurizal, Azri Azzaki Abubakar Azzaki Abubakar, Azzaki Bernard Agus Sakti Dhaki Bernard Agus Sakti Dhaki, Bernard Agus Sakti Birry Karim Bonar, Maruhum Bonar H Browijoyo, Isa A. Budi Sampurna Budi Sampurna C Rinaldi A Lesmana C. Martin Rumende, C. Martin Ceva W. Pitoyo Chairani, Aisha Putri Charlex, Harold Jefferson Matthew Cleopas Martin Rumende Cleopas Martin Rumende Cleopas Martin Rumende Cophiadi Irawan Cosphiadi Irawan Dadang Makmun Damayanti Sekarsari Dedi Wihanda, Dedi Dewi Gathmyr Diah Martina, Diah Dian R. Sawitri, Dian R. Diana Sunardi Dono Antono Dyah Purnamasari Dyah Purnamasari E Mudjaddid E Mudjaddid, E E. Mudjaddid E. Mudjaddid, E. Mudjaddid Eddy Mart Salim Eddy Mart Salim, Eddy Mart Edi Mulyana, Edi Edward Faisal Edward Faisal Edward Faisal Edy Rizal Wahyudi Eka Ginanjar Elizabeth Yasmine Elizabeth Yasmine, Elizabeth Em Yunir Em Yunir Em Yunir, Em Endang Susalit Endy Novianto Endy Novianto, Endy Erlita, Diana Erni Juwita Nelwan, Erni Juwita Esa, Dekta Filantropi Evy Yunihastuti Fahmi Razi Darkuthni Faisal, Edward Felicia Kurniawan, Felicia Ferliani Ferliani Ferliani Ferliani, Ferliani Ferry Tigor P Purba Ferry Tigor P Purba, Ferry Tigor P Fiastuti Witjaksono Findy Prasetyawati Findy Prasetyawati, Findy Firsyada, Fajar Fita Fitrianti Fitrianti, Fita Funay, Prijander L B Ginova Nainggolan Ginova Nainggolan Grecia Rachmaningrum Gurmeet Singh Habibah Hanum Nasution Habibah Hanum Nasution, Habibah Hanum Harahap, Agnes S. Harry Isbagio Harry Isbagio Harry Yusuf Hasan Maulahela Hatma, Ratna Djuwita Hendra Koncoro Henry Ratno Diono Silalahi Henry Ratno Diono Silalahi, Henry Ratno Diono Heri Wibowo Heru Sundaru Heru Sundaru Ibrahim, Febiansyah Idrus Alwi Idrus Alwi Idrus Alwi Ika P Wijaya, Ika P Ika Prasetya Wijaya Ikhwan Rinaldi Ilyas, Mohammad Imam Subekti Imelda Maria Loho, Imelda Maria Indra, Suwito Irawan, Cophiadi Iris Rengganis Irman Firmansyah Irsan Hasan Irvianita, Vinandia Ivona Oliviera, Ivona Jeger, Dian P. Juferdy Kurniawan Kaka Renaldi Katarina, Matilda Kemal Fariz Kalista, Kemal Fariz Ken Ayu Mastini Ken Ayu Mastini, Ken Ayu Kosasih, Kartika Anastasia Kumalawati, July Kuntjoro Harimurti Kurniawidjaja, Meily Kusumaningrum, Profitasari Laurentius Aswin Pramono Leonard Nainggolan Lianda Siregar Linda Armelia Lindrawati Tjuatja Lugyanti Sukrisman Luhuna, Muslimah Lusiani Lusiani Lusiani Rusdi, Lusiani Lutfiah, Evah M Bonar Marbun Mansur, M. Tasrif Marbun, M Bonar Marbun, Maruhum Bonar Hasiholan Marcellus Simadibrata Marcellus Simadibrata K Margaluta, Ariansah Marthino Robinson Marthino Robinson Martin, Cleopas Maruhum B.H. Marbun Maruhum Bonar HM, Maruhum Bonar Masyur, Muhtaruddin Megantara, Marcelino A. Melinda Harini Melinda Harini Mizanul Adli Muhadi Muhadi Muhadi Muhadi Muhadi Muhadi, Muhadi Muhammad Ali Apriansyah Muhammad Ali Apriansyah, Muhammad Ali Muhammad Yamin Muhammad Yamin Murdani Abdullah Murdani Abdullah Murdani Abdullah Murdani Abdullah Nadia Ayu Mulansari, Nadia Ayu Nanda N. Muhammad Nanda N. Muhammad, Nanda N. Nasrun, Martina W. Nikko Darnindro Noorwati Sutandyo Noorwati Sutandyo Noorwati Sutandyo Nunuk Mardiana, Nunuk Nurfitria, Nandika Oryza Gryagus Prabu Parhusip, Santi Sumihar Rumondang Parlindungan Siregar Parlindungan Siregar Petrin Redayani Lukman S Poespitasari, Vinandya Irvianita Pratiwi, Amalia Nur Prihartono, Nurhayati Adnan Prijander Lombardia Funay Pringgodigdo Nugroho, Pringgodigdo Puranto, Rudi Purba, Ferry Tigor P. Purwita Wijaya Laksmi Puspadina, Shafira Putranto, Rud Rachmaningrum, Grecia Raniah, Nida Rasco Sandy Sihombing Rasco Sandy Sihombing, Rasco Sandy Ratih Arianita Agung Reinaldo Alexander Ricardo, William Rino Alvani Gani Rino Alvani Gani Rooshoeroe, A. G. Rudi Putranto Rudi Putranto Rudi Putranto Rudi Putranto Rudy Hidayat Rumagesan, Djahalia Rustam, Musfardi S.Pd. M Kes I Ketut Sudiana . Sabarinah Prasetyo Sally Aman Nasution Salman Paris Harahap Salman Paris Harahap, Salman Paris Sarwono, Sugeng J. Saskia Aziza Nursyirwan, Saskia Aziza Sepmeitutu, Iwandheny Siahaan, Billy Stinggo Sihwastuti, Sihwastuti Simanjuntak, Tiroy Sari Bumi Sinulingga, Dika Sinulingga, Dika I. Siti Setiati Siti Taqwa Fitria Lubis, Siti Taqwa Fitria Soejono, C. H. Suhendro Suwarto Suhendro Suwarto, Suhendro Sukamto Koesnoe Sukamto Koesnoe Sumariyono Sumariyono Suzanna Immanuel Tagor, Alvin Tahir, Andi Cahaya Tanadi, Caroline Tandan, Manu Taufik Rizkian Asir Tedjasukmana, Deddy Teguh Harjono Karjadi, Teguh Harjono Teng, Wei THARIQAH SALAMAH, THARIQAH Tjhin Wiguna Tresia Fransiska U Tambunan Tri Juli Edi Tarigan Triyanta Yuli Pramana Tubagus Djumhana Atmakusumah Valy Wulani, Valy Veronica, Raja Merlinda Victor, Hildebrand Hanoch Virnanda Amu, Ivan Wardoyo, Elizabeth Y Wika Hanida Wika Hanida, Wika Wulyo Rajabto Wuryantoro Wuryantoro, Wuryantoro Yustar Mulyadi Yusuf, Harry Zubairi Djoerban Zubairi Djoerban Zubairi Djoerban Zulkifli Amin Zulkifly, Steven