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All Journal Jurnal Sain Veteriner Jurnal Veteriner Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter Jurnal Bioleuser Jurnal Ilmiah Mahasiswa Veteriner Jurnal Kedokteran Hewan The International Journal of Tropical Veterinary and Biomedical Research Jurnal Medika Veterinaria Jurnal Agripet

Nuzul Asmilia

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Author-ID : 2761650

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Engineering Immunology & microbiology Medicine & Pharmacology Public Health Veterinary Other

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PROFIL DARAH TIKUS PUTIH (Rattus norvegicus) YANG DIINFEKSIKAN Trypanosoma evansi DAN DIBERIKAN EKSTRAK KULIT BATANG JALOH (Salix tetrasperma Roxb) Yudha Fahrimal; Eliawardani E; Afira Rafina; Al Azhar; Nuzul Asmilia
Jurnal Kedokteran Hewan Vol 8, No 2 (2014): September
Publisher : Universitas Syiah Kuala

Penelitian ini bertujuan mengetahui gambaran darah (hematokrit, eritrosit, leukosit, dan diferensial leukosit) tikus yang diinfeksi Trypanosoma evansi (T. evansi) dan diberi ekstrak kulit batang jaloh (Salix tetrasperma Roxb). Duapuluh lima ekor tikus jantan dibagi secara acak ke dalam 5 kelompok perlakuan yang masing-masing terdiri atas 5 ekor tikus. Kelompok 0 (K0) tanpa perlakuan, kelompok I (K1) hanya diinfeksikan dengan 103 T. evansi, kelompok II (K2) diinfeksikan dengan 103T. evansi dan diberikan ekstrak kulit batang jaloh 30 mg/kg bobot badan, kelompok III (K3) diinfeksikan 103 T. evansi dan diberikan ekstrak kulit batang jaloh 45 mg/kg bobot badan, dan kelompok IV (K4) diinfeksi dengan 103 T. evansi dan diberikan ekstrak kulit batang jaloh 60 mg/kg bobot badan. Infeksi T. evansi dilakukan secara intraperitoneal sedangkan ekstrak diberikan secara oral selama 3 hari berturut-turut. Hasil penelitian menunjukkan bahwa rata-rata ± SD nilai hematokrit dan eritrosit tikus dari K1, K2, K3 dan K4 lebih rendah dari K0. Sebaliknya, rata-rata ± SD jumlah leukosit (103/µl) lebih tinggi dari K0. Diferensial leukosit menunjukkan jumlah masing-masing sel leukosit semua tikus dalam kelompok perlakuan meningkat setelah pemberian ekstrak kulit batang jaloh kecuali eosinofil dan limfosit yang justru menurun. Dari penelitian dapat disimpulkan bahwa Infeksi T. evansi menurunkan kadar hematokrit dan eritrosit namun meningkatkan kadar leukosit tikus dan pemberian ekstrak kulit batang jaloh dosis rendah dalam waktu yang singkat mampu mengembalikan profil darah tikus mendekati nilai normal.

PEMBERIAN EKSTRAK EPIDIDIMIS BERPOTENSI MENINGKATKAN KUALITAS SPERMATOZOA KAMBING JANTAN LOKAL Muslim Akmal; Tongku Nizwan Siregar; Sri Wahyuni; Muhammad Hambal; Sugito S; Amiruddin A; Syafruddin S; Roslizawaty R; Zainuddin Z; Mulyadi Adam; Gholib G; Cut Dahlia Iskandar; Rinidar R; Nuzul Asmilia; Hamny H; Joharsyah J; Suriadi S
Jurnal Kedokteran Hewan Vol 9, No 2 (2015): September
Publisher : Universitas Syiah Kuala

Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak epididimis (EE) terhadap peningkatan kualitas spermatozoa kambing jantan lokal. Dalam penelitian ini digunakan 12 ekor kambing jantan lokal, berumur 1,5 tahun dengan bobot badan 10-15 kg dan dibagi atas empat kelompok (K0, KP1, KP2, dan KP3). Kelompok K0, hanya diinjeksi dengan NaCl fisiologis sedangkan kelompok KP1, KP2, dan KP3 diinjeksi EE masing-masing 1, 2, dan 3 ml/ekor selama 13 hari berturut-turut. Pada hari ke-14, dilakukan pengambilan semen kambing dengan elektroejakulator dan selanjutnya dilakukan pemeriksaan kualitas spermatozoa. Hasil penelitian menunjukkan bahwa pemberian EE dengan dosis 1 dan 3 ml/ekor EE selama 13 hari berturut-turut menyebabkan peningkatan kualitas spermatozoa dibanding kelompok kontrol. Berdasarkan hal tersebut dapat disimpulkan bahwa EE berpotensi meningkatkan kualitas spermatozoa pada kambing jantan lokal.

THE EFFECT OF MALACCA LEAVES (Phyllantus emblica) ETHANOLIC EXTRACT ON Plasmodium falciparum GROWTH IN VITRO Nuzul Asmilia; T Armansyah TR; Dwinna Aliza; Juli Melia; Erdiansyah Rahmi; Lingga Surya Maret Daulay
Jurnal Kedokteran Hewan Vol 12, No 4 (2018): December
Publisher : Universitas Syiah Kuala

The aim of this research was to find out in vitro antiplasmodium activity of Malacca leaves (Phyllantus emblica) ethanolic extract against Plasmodium falciparum growth. In this study, Plasmodium culture contained 5% parasitemia in ring stage was cultured using candle jar method and antiplasmodial activity test was carried out using microculture. The treatments were divided into 7 groups with four repetitions. K1 as negative control group was given Roswell Park Memorial Institute (RPMI), while K2 as positive control group was given artesdiaquine. Groups K3, K4, K5, K6, and K7 group was added with 100 µg/mL, 75 µg/mL, 50 µg/mL, 25 µg/mL, and 5 µg/mL of Malacca leaves ethanolic extract, respectively. Antiplasmodial activity was determined by inhibition concentration of 50% parasite growth (IC50). The data were analyzed using ANOVA and followed by Duncan test. The average of parasitemia level in group K1, K2, K3, K4, K5, K6, and K7 were 55.25±15.62, 8.50±2.52, 8.50±3.00, 9.25±0.95, 9.00±2.70, 9.79±2.06, and 10.75±2.22, respectively. The average of inhibition percentage in group K1, K2; K3; K4; K5; K6; and K7 were 0.00±0.00%, 84.62±4.55%; 84.62±5.43%; 83.26±1.73%; 83.71±4,90%; 82.35±3,73%; and 80.54±6.83%, respectively (P0.01). The results showed that the administration of malacca leaves ethanolic extract significantly affect (P0.01) the inhibition of Plasmodium growth as compared to group K1 (negative control). Probit analysis reveals the IC50 value was 3.889 µg/mL. In conclusion, all doses of malacca leaves ethanolic extract used in this study was able to inhibit Plasmodium falciparum growth with IC50 value was 3.889 µg/mL.

UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN MALAKA (Phyllantus emblica) TERHADAP MENCIT (Mus musculus). (Acute Toxicity Test of Ethanolic Extract of Malaka (Phyllantus emblica) Leaves on Mice (Mus musculus)) T. Armansyah TR; Sudi Indriany; Amalia Sutriana; Rosmaidar Rosmaidar; Nuzul Asmilia; Budianto Panjaitan; Dwinna Aliza; Hamdan Hamdan
Jurnal Kedokteran Hewan Vol 10, No 2 (2016): September
Publisher : Universitas Syiah Kuala

ABSTRACT The aim of this research was to asses the acute toxicity of ethanolic extract of malaka leaves using lethal dose 50 (LD50) on mice (Mus musculus). Twenty male mice weighing between 20-30 g were randomly divided into 4 groups (group K1-K4) of 5 mice each. All mice in group K1, K2, K3, and K4 were administered ethanolic extract of malaka leaves with the dose of 2, 4, 8, and 16 g/kg bw, respectively. Single dose of ethanolic extract of malaka leaves were given by oral gavage prior to clinical observation . The observation period was 14 days post administration, for sign of toxicity symptom, weight loss, and mortality. The result showed that no mortality was observed in the experimental animals during this study. Slight reduction of body weight was observed in group K2, K3, and K4, and no toxicity sign was found during fourteen days of observation. The LD50 of ethanolic extract of malaka leaves was higher than 16 g/kg body weight, thus, the substance was practically non toxic substance.

The Effect of Ethanol Extract of Malacca Leaves (Phyllanthus emblica) on The Number of Fibroblast Cells in White Rats (Rattus norvegicus) Burns Wound Ajirni Ajirni; Nuzul Asmilia; Nazaruddin Nazaruddin; Amalia Sutriana; Dian Masyitha; Muhammad Isa
The International Journal of Tropical Veterinary and Biomedical Research Vol 5, No 2 (2020): Vol. 5 (2) November 2020
Publisher : The Faculty of Veterinary Medicine of Syiah Kuala University

Burns are caused by heat exposure, such as fire, radiation, electricity or chemicals that can damage the skin and affect the body's systems. The aim of this study was to find out the effect of the ethanol extract of Malacca leaves (Phyllanthus emblica) on the number of fibroblast cells in white rats (Rattus norvegicus) that have burned. This study used 24 white rats (Rattus norvegicus) were divided into 4 groups that smeared with aquadest as a negative control (P1), 5% ethanol extract gel of Malacca leaves (P2), 10% ethanol extract gel of Malacca leaves (P3), and positive control applied with bioplasenton® gel (P4). The IIA degree burn were created by placing a 2x2 cm hot iron plate on the back of the rat for 5 seconds. The euthanasia performed to all animal and the skin samples were collected after 15 days of treatment. Then histopathological preparations were made using HE staining. The number of fibroblast cells were analyzed by ANOVA test. The average number of white rats (Rattus norvegicus) fibroblast cells that suffered burns P1 (negative control) had a number of 7 ± 1.4 cells/visual. Whereas th e P2 group had a number of 4.2 ± 1.58 cells/visual. This value has a significant difference with the negative control. But the P2 and P3 values (3 ± 1.51 cells/visual) there is no significant different with the P4 value (positive control) with an average number of P4 fibroblast cells were 2 ± 0.4 cells/visual. The results of this study concluded that the ethanol extract of malacca leaves 5% and 10% had an effect againts accelerating burns healing in white rats ( Rattus norvegicus).

KADAR HEMOGLOBIN SELAMA INDUKSI ANESTESI PER INHALASI DAN ANESTESI PER INJEKSI PADA ANJING LOKAL (Canis lupus familiaris) Erwin -; Nuzul Asmilia; Zuraida -; Ela Sesdapepi Hadi
Jurnal Medika Veterinaria Vol 7, No 2 (2013): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v7i2.2942

Penelitian ini bertujuan mengetahui pengaruh anestesi per inhalasi dan anestesi per injeksi terhadap kadar hemoglobin anjing lokal. Hewan coba yang digunakan adalah 6 ekor anjing jantan lokal dengan umur 4-5 bulan dengan berat badan 5-6 kg. Anjing dibagi menjadi 2 kelompok, masing-masing kelompok terdiri atas 3 ekor anjing. Kelompok 1 (K1) diinduksi dengan halotan 3%, setelah teranestesi diturunkan menjadi 1% untuk maintenance sedangkan kelompok 2 (K2) diinjeksi dengan ketamin 10 mg/kg bobot badan dan xylazin 1 mg/kg bobot badan. Pengambilan darah dilakukan pada menit ke-0, 10, 20, 30, 40, dan 50 melalui vena cephalica dan dilakukan pemeriksaan kadar hemoglobin dengan metode Sahli. Data yang diperoleh dianalisis menggunakan analisis varian pola split plot. Hasil penelitian menunjukkan bahwa terjadi perbedaan yang sangat nyata (P0,01) terhadap kadar hemoglobin (g/dl) antara anestesi per inhalasi (14,28+1,71) dengan anestesi per injeksi (12,66+0,37), namun tidak terjadi perbedaan yang nyata (P0,05) pada masing-masing periode pengamatan. Dari hasil tersebut dapat disimpulkan bahwa pemakaian anestesi per inhalasi lebih aman dibandingkan anestesi per injeksi berdasarkan kadar hemoglobin.

12. Lipid profile in the Blood of the Sumatran Elephant (Elephas maximus sumatranus) in Elephant Conservation Center (ECC) Saree, Aceh Besar mahmudi kamaruddin; Al Azhar; Arman Sayuti; Zuhrawati Zuhrawati; Nuzul Asmilia; Sri Wahyuni
Jurnal Medika Veterinaria Vol 11, No 1 (2017): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v11i1.4341

This study was done to investigate lipid profile in the blood of Sumatran elephants at the ECC of Saree. In this stud blood samples were drawn from the auricular vein of 8 sumatran elephants at the ECC. Reasurement of total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), and triglicerida (TG) was carried spectrophotometrically by the commercial service of research laboratory in Banda Aceh. The results showed that the average concentrations of total cholesterol, LDL, HDL, and TG in the blood of Sumatran elephants were 155,86±54,39 mg/dL, 40,13±3,40 mg/dL, 101,13±46,16 mg/dL, dan 84,89±32,86 mg/dL. It can be concluded that the average concentrations of the lipid profile in the blood of the sumatran elephants at the ECC in Aceh were higher than that of reported in other subspecies of Asian elephant

PENGARUH PENINGKATAN SUHU TERHADAP JUMLAH ERITROSIT IKAN NILA (Oreochromis niloticus) Puja Cikal Bangsa; Sugito -; Zuhrawati -; Razali Daud; Nuzul Asmilia; Azhar -
Jurnal Medika Veterinaria Vol 9, No 1 (2015): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v9i1.2985

Penelitian ini bertujuan mengetahui pengaruh peningkatan suhu terhadap jumlah eritrosit ikan nila. Sampel yang digunakan adalah darah ikan nila yang berasal dari 18 ekor ikan nila dengan bobot badan berkisar 40-50 g. Rancangan penelitian yang digunakan adalah rancangan acaklengkap (RAL) pola searah dengan tiga perlakuan dan enam kali ulangan. Perlakuan P1 sebagai kontrol merupakan perlakuan dengan suhu akuarium 29±1°C, P2 merupakan perlakuan dengan suhu akuarium 32±1°C, dan P3 merupakan perlakuan dengan suhu akuarium 35±1°C. Ukuran akuarium pada masing-masing kelompok perlakuan adalah 80 x 60 x 40 cm dengan ketinggian air 30 cm. Perlakuan dilakukan selama 15hari dan pada hari ke-16 dilakukan pengambilan sampel darah. Darah diambil melalui vena caudalis. Data dianalisis dengan analisis varian(ANAVA) dan dilanjutkan dengan uji Duncan. Rata-rata (±SD) jumlah eritrosit ikan nila (106/mm3) pada P1, P2, dan P3 masing-masing adalah 3,01x106/mm3; 2,63x106/mm3; dan 2,08x106/mm3. Hasil penelitian menunjukkan bahwa peningkatan suhu berpengaruh (P0,05) terhadap jumlaheritrosit ikan nila. Dapat disimpulkan bahwa peningkatan suhu air 32±1°C dan 35±1°C dalam akuarium dapat menurunkan jumlah eritrosit ikan nila.

PENGARUH PEMBERIAN KACANG PANJANG (Vigna unguiculata) TERHADAP KADAR GLUKOSA DARAH MENCIT (Mus musculus) YANG DIINDUKSI ALOKSAN (Effect of Long Bean (Vigna unguiculata) on Blood Glucose Level of Mice (Mus musculus) Induced by Alloxan) Intan Fitri Aprila; M. Nur Salim; Razali Daud; T. Armansyah; Nuzul Asmilia; Faisal Jamin
Jurnal Medika Veterinaria Vol 9, No 2 (2015): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v9i2.3983

The aim of this research was to find out the effect of long bean (Vigna unguiculata) on level of blood glucose on mice (Mus musculus) induced by alloxan. Twelve mice with the weigh of 25-40 grams and clinically healthy were used in this research. All mice were randomly divided into 4 treatment groups, 3 mice each. K0 was negative control group, only given aquadest. K1, K2, and K3 groups were induced by alloxan 0.5 ml. K1 group was positive control. K2 group was fed with 100 grams long bean mixed with 50 ml distilled water. K3 group was fed with 100 grams long bean mixed with 100 ml distilled water. Long bean was fed orally 0.5 ml every morning and evening for 7 consecutive days. On day eight the examination of blood glucose level was performed. The average level of blood glucose were K0 (142.00±23.39), K1 (167.00±10.54), K2 (122.67±12.50), dan K3 (154.67±16.26) mg/dL. In conclusion, the administration of long bean for seven consecutive days does not decrease blood glucose level on mice induced by alloxan.Key words: blood glucose, alloxan, long bean

20. The Isolation of Salmonella sp. on quail eggs (cortunxi-cortunix japonica) that failed to hatch in Garot, Darul Imarah Subdistrric, Aceh Besar Latifa Suryandari; Erina Erina; Darniati Darniati; Safika Safika; Nuzul Asmilia; M. Nur Salim
Jurnal Medika Veterinaria Vol 12, No 2 (2018): J. Med. Vet.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.med.vet..v12i2.4118

The study aimed to isolate the Salmonella sp on quail eggs that failed to hatch in Garot village, Darul Imarah Subdistrict, Aceh Besar. A total of thirty quail eggs that failed to hatch were examined in microbiology laboratory of Veterinary Medicine Faculty, Syiah Kuala University. Modification of Carter method was used in this study to isolated samples. The eggs were opened for taking the embryo and then it was swabbed with sterile swabs. The swab was put into Selenite Cystine Broth (SCB) and incubated at 37o C for 24 hours. The breed was then transferred onto Salmonella Shigella Agar (SSA). The growing Bacteria were observed for their morphology and Gram staining to make sure the bacteria belonged to the negative Gram. The result showed that 10 of the 30 of quail eggs that failed to hatch were positively infected with Salmonella sp. Based on this study, it can be concluded that the salmonella sp.can be isolated from quail eggs which were not hatched in the farm of Garot, Darul Imarah Subdistrict, Aceh Besar

Co-Authors . Darniati Abd. Rasyid Syamsuri Abdul Harris Abdullah Hamzah Afira Rafina Agung Prayogi Ajirni Ajirni Al Azhar Al Azhar Al Azhar Amalia Sutriana Amiruddin . Amiruddin A Amiruddin Amiruddin Amiruddin Amiruddin Angga Putra Adinata arif gumilar Arman Sayuti Arman Sayuti Arman Sayuti Asri Rizky Asri Rizky Awaluddin Awaluddin Ayu Andella Agustina AZHAR - Baradillah Abdyad Budi Panjaitan Budianto Panjaitan Budianto Panjaitan Connie Asty Pakpahan Cut Dahlia Iskandar Cut Nila Thasmi Cut Nurlaila Sari Dasrul Dasrul Dasrul Dasrul Delvy Yuana Mustika Dian Masyitha Dina Maulidya Siregar Doly Ihsan Siregar Dwina Aliza Dwinna Aliza Ela Sesdapepi Hadi Eliawardani Eliawardani Emilaza Pratama Erdiansyah Rahmi Erdiansyah Rahmi Erdiansyah Rahmi Erina Erina Erina Erina Erina Erina Erina Erina Erwin - Erwin Erwin Erwin Erwin Etriwati E Fadli Saputra Faisal Jamin Fakhrurrazi Fakhrurrazi Fakhrurrazi Fakhrurrazi Farida Athaillah Fauzan Fajri Fitriani Fitriani Florentina Magdalena Girsang Gholib Gholib Ginta Riady Ginta Riady Hamdan Hamdan Hamdan Hamdan Hamdani Budiman Hamny Sofyan HEFRI YUNALDI Hennivanda Hennivanda Herdina Mayuri Herrialfian Herrialfian Intan Firdaus Intan Fitri Aprila Ismail Ismail Ismail Ismail Jauhari Jauhari Joharsyah J Juli Melia Latifa Suryandari Lingga Surya Maret Daulay M Isa M Jalaluddin M. Hanafiah M. Hasan M. Hasan M. Hasan M. Isa M. Isa M. Isa M. Nur Salim Mahdi Abrar mahmudi kamaruddin Maryulia Dewi Mentari Azhari L Muhammad Hambal Muhammad Hambal Muhammad Hanafiah Muhammad Hasan Muhammad Isa Muhammad Jalaluddin Mulyadi Adam Mulyadi Adam Muslim Akmal Muslim Akmal Mustafa Sabri Muttaqien Bakri Muttaqien Muttaqien Nada Sarah Syahputri Nadia Hanifah Nauval Gibran Lubis Nazaruddin N Nazaruddin Nazaruddin Nellita Meutia Niko Febrianto Novi Masitah Novredha Rahmadita Priyo Sambodo Puja Cikal Bangsa Putri Dewi Razali Daud Razali Daud Rinidar R Rinidar Rinidar Rinidar Rinidar Rinidar Rinidar Rizki Ading Anugrah Robbi Ghani Roslizawaty - Roslizawaty R Roslizawaty Roslizawaty Roslizawaty Roslizawaty Roslizawaty Roslizawaty Roslizawaty Roslizawaty Rosmaidar Rosmaidar Rosmaidar Rosmaidar Rusli Rusli Rusli Rusli Safika S, Safika Siti Aisyah Siti Maghfirah Sri Wahyuni Sudi Indriany Sugito - Sugito Sugito Suriadi S Syafruddin S Syafruddin Syafruddin Syafruddin Syafruddin Syinta Ramadhani t fadrial karmil T. Armansyah T. Armansyah T. Armansyah T. Armanyah TR T. Fadrial Karmil T. Reza Ferasyi Tazul Arifin Tongku Nizwan Siregar Tongku Nizwan Siregar Triva Murtina Lubis Triva Murtina Lubis Ummu Balqis Yola Heryanita Yola Kartika Yolanda Sari Yopi Mardian Yudha Fahrimal Yudha Fahrimal Yusmadi Yusmadi Zainuddin Z Zainuddin Zainuddin Zea Ochtavia Zuhrawati - Zuhrawati NA Zuhrawati NA Zuhrawati Zuhrawati Zuhrawati Zuhrawati Zuhrawaty NA Zuhrawaty Zuhrawaty Zuraida - Zuraidawati Zuraidawati Zuraidawati Zuraidawati

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