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All Journal Jurnal Ilmu Pertanian Indonesia Cannarium (Jurnal Ilmu-ilmu Pertanian) Jurnal Riset Kimia Jurnal Manajemen Dan Kewirausahaan Konversi Jurnal Bioedukasi Jurnal Penelitian Pendidikan IPA (JPPIPA) JPM (Jurnal Pemberdayaan Masyarakat) Jurnal Gizi dan Pangan Soedirman (JGPS) JURNAL PengaMAS Inovator : Jurnal Manajemen International Journal of Supply Chain Management Seminar Nasional Lahan Suboptimal EDUKATIF : JURNAL ILMU PENDIDIKAN FIRM: Journal of Management Studies PREPOTIF : Jurnal Kesehatan Masyarakat Al-Kharaj: Jurnal Ekonomi, Keuangan & Bisnis Syariah Science Midwifery Jurnal Darma Agung GANDRUNG: Jurnal Pengabdian Kepada Masyarakat Siyasatuna Jurnal Ilmiyah Mahasiswa Siyasah Syariyyah NUCLEUS: Jurnal Sains dan Teknologi Jurnal Pengembangan Masyarakat Lokal Al-Ulum: Jurnal Pendidikan Islam JOURNAL LA MEDIHEALTICO International Journal of Educational Review, Law And Social Sciences (IJERLAS) JCDD Jurnal Pendidikan dan Profesi Keguruan Jurnal Manajemen dan Profesional Journal of Indonesian Management Window of Nursing Journal Al-Ulum: Jurnal Pendidikan Islam Journal Of Human And Education (JAHE) Agrikan: Jurnal Agribisnis Perikanan Edu Research : Jurnal Penelitian Pendidikan YASIN: Jurnal Pendidikan dan Sosial Budaya SAINTI: Majalah Ilmiah Teknologi Industri Saksama: Jurnal Sastra JAMAS: Jurnal Abdi Masyarakat Journal of Management Accounting, Tax and Production Jurnal Pengabdian Khairun Student Research Journal SCLS Jurnal Pertanian Khairun (JPK) GEMBIRA (Pengabdian Kepada Masyarakat) Jurnal Pengembangan Masyarakat Lokal Pengertian: Jurnal Pendidikan Indonesia (PJPI) Pajak dan Manajemen Keuangan Journal of Multidimensional Management Pinisi: Physics Journal
Rima Melati
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Determination of Apoptosis Level of Hela Cells Treated with Disobinol Compound from Chisocheton Macrophyllus Plant Hafiz, Ersanda; Albayyinah, Dyandra Hera; Melati, Rima; Herlina, Tati; Permadi, Nandang; Amalia, Riezki; Nurlelasari, Nurlelasari; Gaffar, Shabarni
Jurnal Riset Kimia Vol. 16 No. 1 (2025): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v16i1.772

Abstract

Disobinol is a limonoid compound from the seeds of the Chisocheton macrophyllus plant that has been reported to have anticancer activity against cervical cancer cell lines. Cervical cancer is a type of cancer caused by infection with Human papillomavirus (HPV) types 16 and 18, leading to the transformation of normal cervical epithelial cells into cancerous cells. Previous studies show that Disobinol has a cytotoxic effect on HeLa cells with the IC50 value 52,92 μg/mL (24 hours’ incubation). This study aims to determine the level of apoptosis in HeLa cells treated with Disobinol and observe the DNA fragmentation in HeLa cells undergoing apoptosis. The HeLa cells were treated with Disobinol at concentrations of 26,5 μg/mL (1/2 IC50), 52,3 μg/mL (IC50), and 104,6 μg/mL (2x IC50) and incubated for 24 hours. The level of apoptosis was analyzed by using flow cytometry, and the DNA fragmentation pattern was analyzed by agarose gel electrophoresis. The results showed that Disobinol induces early apoptosis in HeLa cells, although the difference in the percentage of cell death is not very significant, which were 37.05%, 37.7%, and 41.60%, respectively. The DNA fragmentation pattern in HeLa cells treated with various concentrations of Disobinol was also observed on agarose gel. Therefore, Disobinol has the potential to be used as a chemotherapeutic drug or as a lead compound for the treatment of cervical cancer.
Innovative Training on HOTS Learning and Digital-Based Literacy and Numeracy Question Development Tiok Wijanarko; Fitria, Yanti; Ladiva, Hasmai Bungsu; Rifa’i, Muhammad; Melati, Rima; Adrimal, Adrimal; Zuryanty, Zuryanty; Susanto, Nugroho
GANDRUNG: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 1 (2025): GANDRUNG: Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Olahraga dan Kesehatan, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/gandrung.v6i1.4421

Abstract

Understanding Higher Order Thinking Skills (HOTS) is crucial for elementary school teachers to develop students' critical, creative, and analytical thinking abilities. However, many teachers still face challenges in designing HOTS-based learning and developing science literacy and numeracy questions that are relevant to real-world contexts. This study aimed to provide training for teachers in V Koto Kampung Dalam District, Pariaman, in designing HOTS-based learning and digital-based science literacy and numeracy assessments. The method included pre-test, material presentation, post-test, and guided assignments. The results showed a significant improvement in teachers' understanding and skills, with the average pre-test score for HOTS-based learning increasing from 60.43 to 80, and the average score for developing science literacy and numeracy questions rising from 70 to 90 after the training. These findings highlight the importance of continuous training to enhance teachers' competencies in preparing students to face the challenges of the 21st century
Pemanfaatan Lahan Pekarangan dalam Upaya Membudidayakan Tanaman Hortikultura dengan Teknik Vertikulture di Desa Faudu Kecamatan Pulau Hiri Arifin, Tuti Handayani; Darmawan, M.; Melati, Rima; Andi Mahmud, Shubzan
Jurnal Pengabdian Khairun Vol 2, No 2 (2023)
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/jepk.v2i2.7372

Abstract

Lokasi padat penduduk membuat Desa Faudu kekurangan lahan untuk dapat digunakan sebagai lahan budidaya tanaman sehingga pemanfaatan lahan pekarangan dengan teknik vertikulture adalah salah satu cara yang dapat diterapkan oleh masyarakat.  Vertikulture merupakan Teknik budidaya tanaman secara vertikal, dimana penanamannya dilakukan secara bertingkat sehingga memungkinkan untuk berkebun dengan memanfaatkan tempat secara efisien. Kegiatan ini dilaksanakan di Desa Faudu Kecamatan Pulau Hiri dengan menggunakan metode sosialisasi dan pelatihan yang dihadiri oleh masyarakat umumnya ibu-ibu rumah tangga dengan tujuan dapat menjadi solusi dalam penyediaan bahan pangan bagi keluarga. Capaian dari kegiatan ini adalah masyarakat sangat tertarik untuk memulai budidaya tanaman dengan memanfaatkan pekarangan mereka dengan harapan dapat menikmati hasil budidaya tanaman bersama keluarga.
Memasyarakatkan Bunga Telang Sebagai Pewarna Alami Pembuatan Makanan Dan Minuman Di Desa Yamli Kec. Gane Barat Selatan Halmahera Selatan Arifin, Tuti Handayani; Suwarno, Kuwad; Soenarsih DAS, Sri; Haryanto, Sugeng; Syafi, Sartika; Melati, Rima; Mandea, Abd. Rahmat; ., Suleyman; Darmawan, M.
Jurnal Pengabdian Khairun Vol 3, No 2 (2024)
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/jepk.v3i2.9073

Abstract

Bertujuan untuk memasyarakatkan bunga telang (Clitoria ternatea) sebagai pewarna alami dalam pembuatan makanan dan minuman di Desa Yamli, Kecamatan Gane Barat Selatan, Kabupaten Halmahera Selatan Program Studi Agroteknologi Fakultas Pertanian Universitas Khairun melalui pendekatan partisipatif, kegiatan ini melibatkan masyarakat lokal untuk memahami manfaat dan teknik pengolahan bunga telang sebagai pewarna. Capaian dari kegiatan ini menunjukkan bahwa bunga telang dapat diterima sebagai bahan pewarna alami yang menarik dan sehat, serta memiliki prospek untuk dikembangkan dalam produk makanan dan minuman lokal. Diharapkan bahwa pengenalan bunga telang sebagai pewarna alami ini tidak hanya meningkatkan nilai ekonomi masyarakat setempat, tetapi juga mengurangi ketergantungan pada pewarna sintetis yang berpotensi berbahaya bagi kesehatan.
Stress Drought and Mycorrhizal Dose on the Growth Characteristics of Boci Sawala Pandanga Morotai Local Peanuts Habeahan, Kisey Bina; Samad, Sofyan; Melati, Rima
Jurnal Penelitian Pendidikan IPA Vol 9 No 6 (2023): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i6.3634

Abstract

Mycorrhizal can provide plant resistance when drought came. Thus, this study aims to examine the effect of stress drought and mycorrhizal dose on the growth of Boci Sawala Pandanga Morotai local peanuts. The study was conducted at the BPTP screen house North Maluku in Kusu Village, Tidore Kepulauan City, North Maluku Province from March to June 2022 with the elevation of 50m above sea level. It utilized a factorial design with 2 factors. The first factor is the drought (K) 2 levels (K0 = optimal and K1 = stress), and the second factor is mycorrhizal (M) 4 levels (M0 = 0 g/polybag, M1 = 20 g/polybag, M2 = 25 g/polybag, M3 = 30 g/polybag) with 3 replications. The parameters observed consisted of relative growth rate, flowering age, and number of gynophores. The fingerprint results showed that the Boci Swala Pandanga Morotai local peanuts cultivar is tolerant to drought conditions which can be seen from the relative growth rate, number of ginophores, and the fastest flower. With drought stress conditions by giving mycorrhiza 30 g/polybag of peanuts land, it still grew and worked.
Co-Authors ., Soepeno ., Suleyman Abdul Rahmat Mandea Abdullatif, Zauzah Abrar, Ligadhea Adi, Ricky Fernando Adistia, Erika Adrimal, Adrimal Afrinaldi Afrinaldi Aida, Yuni Aini, Yusrida Albayyinah, Dyandra Hera Alfaqih, Muhammad Subhan Amalia, Riezki Amstrong, Valentinus Andi Mahmud, Shubzan Andi Nurhasanah Anto Satriyo Nugroho, Anto Satriyo Antoni Antoni Anugrah, Andreas Surya Ardi Basri Ardi Basri Ardini Saptaningsih Raksanagara, Ardini Saptaningsih Arifin, Tuti Handayani Arifmiboy, Arifmiboy Arlianti, Pamela Intan Aryanti, Evy Aryanti Asiah Salatalohy Asmail, Asmail Awasinombu, Aidin Hudani Budi Hartono buhari umasugi Darmawan, M Darnis, Afrianto Darul Ilmi Dewi Rahma Fitri Dilfa Rabul Dwirati, Laras Evy Aryanti Fajar, Rahmat Febrianti Nyong Ferianasari, Ineke Winda Ferianasari, Inneke Winda Firdaus, M. Azis Fitria, Yanti Gabriella Tantular, Gabriella Gustin Padwa Sari, Gustin Padwa Habeahan, Kisey Bina Hafiz, Ersanda Halen Dwistia Hayun Abdullah Helda Sabban Hendarmin, R.M. Rum Hi Rauf, Siti Nuraini Humairoh Humairoh Ida Ayu Putu Sri Widnyani Istikhara Istikhara Jamilah, Yeni Johan Lucas Away Khaerul Anwar Khakim , Luqmanul Kinanti Wijaya, Kinanti Kiptiyah, Lutfi Maryatul Kurnia Illahi Manvi Ladewi, Yuhanis Ladiva, Hasmai Bungsu Lia Agustina Damanik Lukman, Mardiana Madi, Riski Amalia Mahyuddin, Meriwati Mandea, Abd. Rahmat Mardiana Lukman Marlen, Liany Mendoza, Muhammad Dominique Misruni, Fitri Mizan, Mizan Montolalu, Ivan Adrian Muh Iqbal Muhammad Bahrul Ulum Muhammad Ridwan Muliadi, Jemie Munir , Nur Wahyuni Mursalin . Mustain Zamhari Nasrullah Armi Nasution, Alliriansyah Nasution, Liantha Adam Nasution, Mawaddah Nasution, MHD. Sangkot Pangidoan Natalia, Desti Fitriani Niamah, Ila Yusrin Nugroho Susanto Nur Ilah Padhila Nur Syafira Rahmadani Nurhasanah, Nurhasanah Nurhasmi Nurlelasari Nurlelasari Nurul Husna Nusasenjaya, Radite Oktaviana, Milenia T. Pamungkas, Lukas Sangka Parulian Siregar Patwayati Patwayati Permadi, Nandang Pradikto, Sugeng Prakoso, Firza Agung Prapdopo Pratama, Ganiviantara Pulungan, Abraham Ismail Purwoko, Reza Yuridian Putra, Edon Sholeh Putra, M. Ridho Amirsyah Putra, Raka Tri Oktaf Rabul, Dilfa Rahayaan, Manuela Rahmah Ningsih, Rahmah Rahmat Hidayat Rahwana , Kusuma Agdhi Ramli Hadun Ridwansyah Ridwansyah Rifa’i, Muhammad Rizki Fadhillah Lubis Robert Junaidi Ruhdiat, Rudi Rusdianto Roestam Sahroh Saputra, Silvan Sarnia, Sarnia Shabarni Gaffar -, Shabarni Gaffar Shinta, Ike Sinarwaty Sunarjo Siti Afifah Sofyan Samad, Sofyan Soleha, Siti Maratus Solita Sri Idaiani Sri Soenarsih DAS Subhan Baswan Sudarmi Sudarmi Sudjud, Suratman Sugeng Haryanto Suharni, Ida Suleyman, Suleyman Sulistia, Alda Wenda Sumengen Sumengen Supriyadi, Muhamad Rodhi Suranta, Eddy Suratman Sudjud Suryani, Bella Suryati Tjokrodiningrat Suwarno, Kuad Suwarno, Kuwad Suyanto Suyanto Syafi, Sartika Syafira, Eka Suci Tanjung, Riska Pratama Tati Herlina Terzaghi, Muhammad Titan Theresia Santi, Theresia Tiok Wijanarko Veronica, Meilin Wahyu Pratama Wan Sen, Tjong Wan Sen Widad A, Rafa Wijaya , Deden Sukma Yulia Nor Frasisska Yunita, Jasrida Yunus Syafie Yusnita , Rita Tri Zakirah, Fadilah Nur Zasti Indrianty Joisangadji Zasty Indriani Zauzah Abdullatif Zulkarnain Zulkarnain Zuryanty, Zuryanty