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All Journal Natural Science: Journal of Science and Technology Al-'Adalah Biocelebes JURNAL PHARMASCIENCE JURNAL PENGABDIAN KEPADA MASYARAKAT PENA SAINS Pharmascience Daya Saing : Jurnal Ilmu Manajemen Jurnal Farmasi Sains dan Komunitas Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Al-Albab Jurnal Pengabdian Pada Masyarakat Al-Hayat: Journal of Islamic Education GHIDZA: Jurnal Gizi dan Kesehatan Pharmacology and Clinical Pharmacy Research JSFK (Jurnal Sains Farmasi & Klinis) AL-TANZIM : JURNAL MANAJEMEN PENDIDIKAN ISLAM Journal of Islamic Law Jurnal Ilmiah Medicamento ADDIN Ulumuna Jurnal Locus Penelitian dan Pengabdian Jurnal Economica: Media Komunikasi ISEI Riau Journal of Health, Education, Economics, Science, and Technology (J-HEST) Jurnal Bisnis Kompetitif Tahqiqa: Jurnal Pemikiran Hukum Islam Jurnal Pendidikan, Kebudayaan dan Keislaman Molekul: Jurnal Ilmiah Kimia JIPI (Jurnal IPA dan Pembelajaran IPA) Journal of Public Health and Pharmacy Jurnal Pengabdian Kompetitif Journal Of Chemical Process Engineering Jurnal Pengabdian Farmasi dan Sains Integrated and Sustainable Agriculture Journal of Tropical Pharmacy and Chemistry Jurnal Sains dan Kesehatan Journal of Muhammadiyah’s Application Technology Journal Social Civilecial
Yusriadi Yusriadi
Universitas Tadulako
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Journal : Natural Science: Journal of Science and Technology

 1 
UJI EFEK ANTIPIRETIK KOMBINASI EKSTRAK ETANOL HERBA SAMBILOTO (ANDROGRAPHIS PANICULATA BURM.F. NEES.) DAN EKSTRAK ETANOL DAUN BELIMBING WULUH (AVERRHOA BILIMBI L.) PADA TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) Ibrahim, Nurhalifah; Yusriadi, Yusriadi; Ihwan, Ihwan
Natural Science: Journal of Science and Technology Vol 3, No 3 (2014): Volume 3 Number 3 (December 2014)
Publisher : Univ. Tadulako

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Abstract

This research is about antipyretic effect of combination ethanol extract of sambiloto (Andrographis paniculata Burm.f. Nees.) herbsand ethanol extract of  belimbing wuluh (Averrhoa bilimbi L.) leaves in white male rats (Rattus norvegicus)which induced by 5 % pepton, in order to know the effect of combination and to determine the most effective dose as an antipyretic. Extract was prepared by maceration method using 70% ethanol. White rats were grouped into 7 difference treatment. Each rat was induced by using 5% peptone in dose of 250 mg/200 g Body Wight (BW). The first group was given Na CMC as a negative control. The second group was given paracetamol as a positive control. Groups of 3rd, 4th, 5th, 6th and 7th were given a combination of ethanol extract sambiloto (A. paniculata Burm.f. Nees.) herbs and ethanol extract belimbing wuluh (A. bilimbi L.) leaves in doses of (200 + 0) mg/200 g BW,  (150 + 50) mg/200 g BW, (100 + 100) mg/200 g BW, (50 + 150) mg/200 g BW, and  (0 + 200) mg/200 g BW, respectively. Temperature measurements of antipyretic were done for 3 hours in 30 minutes interval. Temperature data were statistically analysed using ANOVA (Analisys Of Variance) one way Anova method. The result of research was showed that combinationextract could reduce thefever. The most effective combination as an antipyretic was ethanol extract of sambiloto (A. paniculata Burm.f. Nees.) Herbs 150 mg and ethanol extract of belimbing wuluh (A. bilimbi L.) leaves 50 mg (150 + 50) mg/200 g BW. The dose has antipyretic effects that was not significant different to the positive control group(paracetamol treatment).
FORMULASI GEL EKSTRAK ETANOL DAUN KELOR (MORINGA OLEIFERA LAM) SEBAGAI ANTIOKSIDAN Hasanah, Uswatun; Yusriadi, Yusriadi; Khumaidi, Akhmad
Natural Science: Journal of Science and Technology Vol 6, No 1 (2017): Volume 6 Number 1 (March 2017)
Publisher : Univ. Tadulako

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Abstract

Senyawa antioksidan dapat mengurangi efek buruk radikal bebas terhadap kulit. Daun kelor (Moringa oleifera Lam) mengandung senyawa antioksidan dengan potensi aktivitas yang kuat. Penelitian ini bertujuan untuk membuat sediaan gel antioksidan dengan menggunakan karbomer sebagai basis gel dan ekstrak etanol daun kelor dengan konsentrasi untuk F0, F1, F2 dan F3 adalah 0%, 1%, 2% dan 3%, yang kemudian dievaluasi dan diuji aktivitas antioksidannya. Pengujian aktivitas antioksidan dilakukan dengan metode penentuan IC50 menggunakan reaksi DPPH (Difenil-2-pikrilhidrazil). Hasil uji aktivitas antioksidan ekstrak etanol daun kelor adalah 89,305 ppm dan vitamin C sebagai senyawa pembanding adalah 8,374 ppm. Evaluasi sediaan gel meliputi pengamatan homogenitas, organoleptis (warna, aroma dan konsistensi), viskositas dan pH selama 28 hari. Aktivitas antioksidan ekstrak etanol daun kelor dalam sediaan gel dihari pertama adalah 129,245 ppm (F1), 116,875 ppm (F2) dan 97,484 ppm (F3), sedangkan dihari ke-28 adalah 178,236 ppm (F1), 148,589 ppm (F2) dan 143,333 ppm (F3). Hasil uji sifat fisik sediaan gel menunjukkan bahwa semua sediaan gel homogen dan tidak mengalami perubahan warna dan aroma, sedangkan konsistensi dari hasil uji viskositas mengalami perubahan signifikan setelah 28 hari dan hasil uji pH semua sediaan selain F3 juga mengalami perubahan signifikan setelah 28 hari. Berdasarkan hasil penelitian ini, disimpulkan bahwa ekstrak etanol daun kelor dapat diformulasi dalam sedian gel antioksidan dengan konsentrasi terbaik adalah 3%
Co-Authors A. Khairinisa, Miski A.A. Ketut Agung Cahyawan W Adam, Aisyah Azhar Ade Fazliana Mantika Agus Syahrani Agustinus Widodo Akhmad Khumaidi Alowisya Futwembun Alwiyah Mukaddas Alwiyah Mukaddas Amal, Citra Amalia amelia rumi, amelia Amri, Faizal Anak Agung Istri Sri Wiadnyani Anderbeck, Karl Andi Alfianto Andi Mustika Andi Nuddin Andi Ratihsekarningrum Siradje Apriyana Soputra Aqdar Fitrah, Muhammad Ardiansah, Ardiansah Ari Prabowo Arminas, Arminas Armini Syamsidi Asfar, Dedy Ari Asriana Sultan Asty Ivon Samaliwu Azzahra, Najwa Salsabilla Birdayanthi, Birdayanthi Cristadeolia Oktaviani Cristadeolia Oktaviani, Cristadeolia David Pakaya Desa, Susilo Sudarman Deviana, Alda Didi Darmadi, Didi Dilla Aldilla Dinda Rahmiyati Dwi Lestari Handayani Dytha Okvhyanitha Evi Sulastri Febry Astuti Abu Fia Lestari, Mega Fina Ulviani Finta Amalinda Friskilla Friskilla Gugun Gunawan Hasniar Hasniar Hasriyanti, Nunik Heni Pujiastuti Hidayat, Novit Idrus, Irnawaty Ika Olivia Borman Ikmal, Ikmal Imron Muttaqin, Imron Ince Agus Nurcholis Ingrid Faustine Ismail, Nur Afia Jamaluddin Jamaluddin Jamaluddin Jamaluddin Janes Krisly Jessica Jessica Joko Tri Haryanto Joni Tandi, Joni Juniawati Khaerunnisa, Munira Khildah Khaerati Klerensia Defneir Titing Lestari*, Mega Fia Lestari, Mega Fia lubis, kartika sari M Sulaiman Zubair M Yusuf Miftahul Jannah Moh. Rifki Muhamad Rinaldhi Tandah Muhammad Faisal Muhammad Rinaldhi Tandah Muhammad Sulaiman Zubair Munawar Munawar Muthi’ah H Z Mutiani, Santi Nandiska Maladjili Natasya, Putri Nela Sharon Norawati, Suarni Nordin, Zaimuariffudin Shukri Novianti Batti Novita Christiana Ponganan Nur Amri, Azhari Nur Fuady, Muhammad Ikram Nur Hamzah Nurhalifah Ibrahim Nurlaila Ramadhani Nuur Aanisah Paddiyatu, Nurhikmah Padhlun A Jerni Papriani, Nada Pertiwi Pebrianti Pebrianti Pohan, Yuli Arnida Pramita Putri Pramita Putri Purwanti, Rani Ramadhani, Nurlaila Ririen Hardani Ritha Pratiwi Rochaeti , Nur Ruslan, Ismail Sahabuddin Latif, Sahabuddin Saipul Maulana Seprililianti Seprililianti Serli, Serli Shin, Chong Shukri bin Nordin, Zaimuarifuddin Siti Nurhafsah Sri Sulistiana Suhaeni Zainuddin Suherman, Suherman Syahsudarmi, Siti Syarifuddin, Nuryani Syariful Anam Tamba, Nesli Towolioe, Sherly Tri Novrianti Djanggola Tricia Andini Tuah, Dilah Tuah, Dilah bin Utami, Hermin Hardyanti Wardatul Nurjannah Yantama, Akmal Andri Yonelian Yuyun Yuliet Yuliet Yusri, Andi Zainuddin, Suhaeni