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Apendisitis Akut pada Pasien Usia Lanjut: Laporan Kasus Noval Ramadirta; Winda Trijayanthi Utama
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1890

Abstract

Acute appendicitis is one of the most common surgical abdominal emergencies and may lead to severe complications such as perforation if not promptly and appropriately managed, particularly in elderly patients who often present with atypical clinical features. This case report aims to describe the diagnostic approach and management of acute appendicitis in an elderly patient using a comprehensive clinical, laboratory, and imaging-based evaluation. A 64-year-old male presented with right lower quadrant abdominal pain preceded by periumbilical pain, accompanied by nausea and vomiting. Physical examination revealed right lower quadrant tenderness with a positive McBurney sign without generalized peritoneal irritation. Laboratory findings showed leukocytosis with neutrophil predominance, while abdominal ultrasonography suggested acute appendicitis with suspected periappendiceal abscess. Based on the Alvarado and RIPASA scores, the patient was classified as high probability for acute appendicitis and underwent appendectomy. Intraoperative findings revealed non-perforated acute appendicitis without abscess formation, establishing the definitive diagnosis of uncomplicated acute appendicitis. The patient received empirical antibiotic therapy, analgesics, and definitive surgical management with favorable postoperative outcomes without complications. This case highlights that the integration of history taking, physical examination, laboratory tests, imaging, and clinical scoring systems is essential for accurate diagnosis of acute appendicitis, especially in elderly patients with variable clinical presentations, and emphasizes the importance of early surgical intervention to prevent disease progression and complications.
Cataracts in Elderly Patients with Grade 1 Hypertension: Case Reports Elizabeth Mega Sinaga; Winda Trijayanthi Utama
Medula Vol 17 No 1 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v17i1.1955

Abstract

Cataract is one of the leading causes of blindness worldwide, including in Indonesia, particularly among the elderly population. Uncontrolled hypertension is believed to accelerate the development of cataract through mechanisms involving oxidative stress and microvascular dysfunction. This case is reported due to the frequent coexistence of hypertension and cataract in older adults; however, the relationship between systemic risk factor control and visual function preservation is often underemphasized. The aim of this report is to describe the clinical manifestations, risk factors, diagnostic approach, and management of a patient with hypertension and senile cataract. This case report is based on primary data obtained from medical history taking, physical examination, blood pressure measurement, and ophthalmological assessment. A 63-year-old male patient, Mr. H, was diagnosed with grade 1 hypertension and senile cataract, presenting with progressive right eye visual deterioration accompanied by a sensation of haze and glare. Clinical evaluation revealed a blood pressure of 145/93 mmHg, reduced visual acuity, lens opacity, and a positive shadow test, supporting the diagnosis. Management included administration of amlodipine 5 mg, lifestyle modification education such as a low-salt diet, increased physical activity, smoking cessation, and improved medication adherence. The patient was also referred to an ophthalmologist for further evaluation and consideration of phacoemulsification as definitive therapy. This case highlights that early recognition, blood pressure control, and appropriate management play an important role in slowing disease progression and preserving visual function.
Laporan Kasus : Perempuan 61 tahun dengan Katarak Senilis Imatur Okuli Dekstra et Sinistra Faradhila Azqiah Cahyani; Winda Trijayanthi Utama
Medula Vol 17 No 1 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v17i1.1961

Abstract

The eye is one of the sensory organs that functions as the organ of vision. Various ocular disorders can cause visual impairment, one of which is cataract. Cataract is a condition characterized by opacification of the lens, which can lead to impaired visual function. Cataracts can be classified into several types, one of which is senile cataract. Senile cataract is a type of cataract associated with the aging process. It can cause visual disturbances that significantly affect the quality of life of affected individuals. We report the case of a 61-year-old woman who presented to the Ophthalmology Clinic of Dr. A. Dadi Tjokrodipo Hospital with complaints of blurred vision for one year prior to admission, which had progressively worsened over the past month. The patient also complained of cloudy vision, glare, and a foreign body sensation in the eye. Ophthalmological examination revealed visual acuity of 1/60 in both the right and left eyes, with a positive shadow test on physical examination. Based on the clinical findings, the patient was diagnosed with senile cataract. Accurate diagnosis through thorough history taking and comprehensive ophthalmological examination is essential to determine disease severity and appropriate therapeutic management. Adequate treatment can improve visual function, enhance quality of life, and significantly influence the patient's prognosis. This case report aims to discuss the clinical presentation, diagnostic approach, and management of senile cataract in an elderly patient.
Penatalaksanaan Diabetes Mellitus Tipe 2 dengan Komplikasi Selulitis pada Perempuan Usia 50 Tahun: Laporan Kasus Sheilla Amelia Vandela; Winda Trijayanthi Utama
Medula Vol 17 No 1 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v17i1.2005

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder that may lead to various complications, including cellulitis. This case report aimed to implement evidence-based medicine care through a patient-centered and family-oriented approach in a patient with type 2 diabetes mellitus complicated by cellulitis. Data were collected through history taking, physical examination, supporting investigations, and home visits to comprehensively assess the patient's risk factors and overall condition. Interventions included health education, dietary modification, promotion of physical activity, and family involvement in patient care. The results demonstrated improved knowledge among the patient and family members, better adherence to recommended dietary practices, and increased regular physical activity. The family medicine approach was shown to support more comprehensive diabetes management and contribute to complication prevention and improvement of the patient's quality of life.
Perbandingan Absolute Lymphocyte Count (ALC) Antara Pasien Terkonfirmasi Dengan Probable Covid 19 Di RSUD Pesawaran Denny Andika Kurniawan; Winda Trijayanthi Utama
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1763

Abstract

Coronavirus Disease 2019 (COVID-19) is a broad group of viruses known to cause diseases with a diverse clinical spectrum, ranging from mild symptoms to severe disorders in humans. These viruses are zoonotic, meaning they can be transmitted from animals to humans, posing a major challenge in infection control efforts. In addition, variations in immune responses in each individual cause the clinical picture of Covid-19 to vary greatly, including changes in laboratory parameters such as absolute lymphocyte count (ALC). This study was conducted to analyze the differences in ALC values in patients with a confirmed diagnosis of Covid-19 compared to patients categorized as probable Covid-19 at the Pesawaran Regional General Hospital. The study design used an observational analytical method with a cross-sectional approach. Data processing and analysis were performed using an independent t-test to assess the difference in means between the two groups. The total sample consisted of 45 patients, namely 20 patients with confirmed Covid-19 and 25 patients with probable Covid-19. The results showed that the mean ALC value in the confirmed group was 1,241.5/µL, while in the probable group it reached 1,812.59/µL. These findings indicate a statistically significant difference between the mean ALC of the two groups, with a p-value of 0.0001. This difference also supports the findings of previous studies that lymphopenia is more commonly found in patients with verified Covid-19 infection. Thus, this study confirms that Covid-19 confirmation status is associated with changes in ALC, which can be a supporting clinical parameter in the evaluation and monitoring of patient conditions.
Perbedaan Tingkat Pengetahuan Tentang Diabetes Melitus Dengan Kadar Gula Darah Sewaktu Pasien DM Tipe 2 Samintola Dolok Saribu; Winda Trijayanthi Utama
Medula Vol 16 No 3 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i3.1806

Abstract

Diabetes mellitus (DM) is a degenerative disease characterized by elevated blood sugar levels or hyperglycemia. The incidence of DM continues to increase every year, influenced by various factors such as suboptimal recovery, the need for continuous consumption of antidiabetic drugs, uncontrolled blood sugar levels, and low patient knowledge about the disease. This condition can worsen complications and reduce the quality of life of patients. This study was conducted to determine the difference in the level of knowledge about diabetes mellitus with blood sugar levels in type 2 diabetes mellitus patients at Dr. H. Abdul Moeloek Regional General Hospital in Lampung Province. This study used a descriptive method with a cross-sectional study design. Sampling was conducted using non-probability sampling, specifically consecutive sampling, with instruments in the form of questionnaires to measure knowledge levels and random blood sugar level tests. Data were analyzed using the chi-square test to see the relationship between variables. A total of 35 respondents participated in this study, with 11.4% in the good knowledge category, 14.3% in the adequate category, and 74.3% in the poor category. The average blood sugar level of the respondents was 285 mg/dL. The statistical test results showed a p-value of 0.003, indicating a significant difference between the level of knowledge about diabetes mellitus and fasting blood sugar levels. Thus, this study concluded that the level of patient knowledge has a significant relationship with fasting blood sugar levels in type 2 DM patients.
Masa Kerja sebagai Faktor Risiko Gangguan Fungsi Paru pada Pekerja yang Terpapar PM10: Tinjauan Literatur Fitri Maharani; Winda Trijayanthi Utama; M. Yogie Fadli; Sutarto Sutarto
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 6 No. 1 (2026): Maret : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v6i1.9539

Abstract

Occupational exposure to particulate matter (PM₁₀) represents a significant health risk. Although the association between PM₁₀ exposure levels and impaired lung function has been well demonstrated in numerous studies, epidemiological literature shows highly contradictory findings regarding the relationship between exposure duration, commonly measured as “Length of Service” and lung function. To explore the sources of this inconsistency, this review examined literature published between 2020 and 2025 using a narrative synthesis approach. The analysis revealed that the divergent findings are not driven by biological factors, but rather by systematic methodological limitations. Non-significant results in several studies can be attributed to three major weaknesses: (1) Length of Service is a weak proxy variable that fails to capture the crucial intensity (dose) of exposure; (2) substantial statistical multicollinearity between Length of Service and Age, which distorts the estimated associations; and (3) the Healthy Worker Effect (HWE), a selection bias that is almost inevitable in occupational epidemiology studies especially those using cross-sectional designs, which systematically attenuates true associations. Therefore, non-significant findings related to Length of Service should not be interpreted as evidence of the absence of harm from chronic exposure. The relationship likely exists but is “masked” by design biases and the limitations of a weak proxy. Future research should avoid relying on Length of Service as a sole exposure indicator and instead adopt cumulative exposure metrics that are more representative.
Co-Authors Aditia, Arianda Alghani, Sulthan Rafi Amanah, Nur Suci Amelia, Maya Rizky Amir, Anzela Ananda, Amallia Andari, Michelle Safna Andini Pramesti Ningrum Andriani, Silvia Anggraini, Dian Isti Anisa Adelia Anisa Nuraisa Jausal Annisa Auliya Dien Safitrie Arifah Putri Desenia Asep Sukohar Asyifa, Takhfa Nur Azelia Nusadewiarti Azhar, Hafidz Sirojudhin Azmi, Aulia Salma Azzahra, Herina Balqis, Gasela Zalianti Bawono, Aloysius Krishartadi Damar Bayu Anggileo Pramesona Daulay, Suryani Agustina Denny Andika Kurniawan Desta Bulan Cahyarani Dharmesti, Rizky Aleyda Dian Pratiwi Dian Puspita Larasati Dita Ayu Permata Dewi Dwita Oktaria Dyah Wulan Sumekar Rengganis Wardani Elizabeth Mega Sinaga Eniwati Eniwati Evi Kurniawaty Fadhilah, Retno Suci Fadhillah, Paisal Faradhila Azqiah Cahyani Fatharanni, Mentari Olivia Fathia, Nauriel Ferdian, Ruben Fitri Maharani Fitria Saftarina Hafizh, Ahmad Fauzan Haq, Rais Amaral Heironimus Billy Febriyan Helmi Ismunandar Indika Poloriani Tunang Indriyani, Reni Intan Kusumaningtyas Intanri Kurniati Intanri Kurniati Iqbal Lambara Putra Istiqomah, Dinni Jovita, Hasna Laili Khairun Nisa Kurniawaty, Evi Kusuma, Febriyani Dyah Lariza Serafina Tobroni M. Yogie Fadli Maharani, Ardila Putri Maharani, Calista Putri Maharani, Raihan Syifa Maharani, Shella Marcellia, Selvi Maya Ganda Ratna Mersiana, Putri Febi Muhammad Aditya, Muhammad Muhammad Maulana Muhammad Nadhif Rafii Muhartono Muhartono Naisya Midary Mutia Pratiwi Nasser, Ghalib Abdul Ni Putu Swastini Noval Ramadirta Novita Carolia Novita Carolia Nurhardita, Fika Nuriah Nuriah Nurladira, Salsanisa Tisno Nurliwayka Qodri, Amari Oktadoni Saputra Oktafany, Oktafany Pamarta, Rachel Dwyana Poppy Monika Sari Prayogi, Norbertus Marcell Puspitasari, Ratna Dewi Putra, Ruchpy Cahya Putri Puspa Devi Putri, Asyifa Dinda Raehana, Nabila Salwa Raharjo, Shafana Azzahra Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi PS Ratna Dewi Puspita Sari Ratu Nirmala Wahyunindita Rekha Nova Iyos Reni Indriyani Reni Indriyani Reni Indriyani Reynhard Theodorus Xaverius Saragih Riandini, Sabrina Risti Graharti Rizal Effendi, R E Sahputra, Rahmat Tridhandy Salma Alya Ihsan Salsabila Alifiyah Setiawan Salsabila Dzakiyyah Zahra Salsabila Nurislami Samintola Dolok Saribu Sany Setiawan Satria Adi Nugraha Septia Eva Lusina Septiani, Linda Setiorini, Anggi Sheilla Amelia Vandela Shinta Nareswari, Shinta Silvia Andriani Sirait, Naomi Elfriede Situmorang, Cindy Miranda Sofyan Musabiq Wijaya Sofyan Musyabiq Wijaya Stevani Febeline Steven, Nixon Suarto, Sutarto Suharmanto Suharyani Suharyani Suryawinata, Arli Sutarto Sutarto Sutarto Sutarto Sutarto Sutyarso Sutyarso Syazili Mustofa Syifa Rahmi Fadhila TA Larasati Tasya Nadia Putri Tri Umiana Soleha Tyaradhia Ranita Eltidar Utomo, Muhammad Aditya W, Sofyan Musyabiq Waluyo Rudiyanto Wardani, Nanda Fitri Widjaja, Jovan Zahra, Tsurayya Fathma