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Pengobatan penyakit tumor mammae melalaui operasi (matektomi dan ovariohisterektomi) dan kombinasinya (tanaman herbal) pada hewan Gunanati Soedjono; Bambang Pontjo Priosoeryanto; Ietje Wientarsih; Ros Sumarny
Jurnal Ilmu Pertanian Indonesia Vol. 14 No. 1 (2009): Jurnal Ilmu Pertanian Indonesia
Publisher : Institut Pertanian Bogor

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Abstract

Tumor or neuplasm can be meant as a abnormal and uncontrol growth of the transformation tissue or the change of one or main location of the body. This degenerative desease is one of the deseases in the animal pet especially dog and cat. Generaly this tumor deseases can be used with therapy using surgery and usually will relapse after six months. from our previous research had succeded to examp by using activity in vitro antiproliverati from extract plant (nusa indah, blustru and temu putih) combined with recombinanct interferon dog ( rCaiFN). The above phenomenon indicate a new hope to make a therapy for tumor desease, especially for dog and cat and may be in the future can be used for human. In this research we used 21 female rabbits and divided into 7 treatment groups, consisted of 3 rabits ie : group A. negative control; B. surgery, preventive and curative curcumine; C. positive control; D. positive control and surgery; E. surgery and preventive zedoaria capsul; F. surgery , preventive and curative zedoaria capsule and G. surgery and curative zedoaria capsule . Induction with carcinogen (MNU) treated every weeks during 3 weeks. Surgery is executed in the 5 weeks and giving capsule zedoaria is executed every day for 4 weeks (preventive or curative) and 8 weeks (preventive andcurative). Result of the research indicated that mammae tumor has been made successfully by MNU (n-metil-nnitrosuria) induction to rabit and capsule zedoaria and it has been treated by doing surgery therapy (mastectomy and ovariohisterectomy). Also decombination of zedoaria capsule. The result of the research indicated lindrance of tumorgenesis to the group which is given by zedoaria capsule. from the clinical picture shows that zedoaria capsule does not give negative effect to clinical picture (temperature, respiratory frequency and heart rate)/ still normal to all the groups. Tumor induction with (MNO) at mammary gland will occur allegic reaction inflammatory which is the beginning of tumor mechanism which is marked by total leucosit, neutrofil, eosinofil, and basofil increase. Tumor therapy with surgery (masektomi and ovariohisterektomi) and the combination with rimpang Temu Putih capsule can decrease the number of leucosit, neutrofil and limfosit but only a little affectmonosit number, although statistically it does not show real difference.
EFEK KONSUMSI MINUMAN BUBUK KAKAO (Theobroma cacao L.) BEBAS LEMAK TERHADAP SIFAT ANTIOKSIDATIF LIMFOSIT SUBYEK PEREMPUAN [The Effect of Fat Free Cocoa (Theobroma Cacao L.) Powder Drinks Consumption on Antioxidative Activity of Lymphocyte of Women Subjec . Erniati; Fransiska R. Zakaria; Bambang Pontjo Priosoeryanto
Jurnal Teknologi dan Industri Pangan Vol. 23 No. 1 (2012): Jurnal Teknologi dan Industri Pangan
Publisher : Departemen Ilmu dan Teknologi Pangan, IPB Indonesia bekerjasama dengan PATPI

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Abstract

The health benefits of cocoa both in vivo and in vitro have been reported in many studies. Cocoa is a rich source of flavonoids known to have antioxidant activity, such as catechin, epicatechin and procyanidin. The aim of this research was to evaluate the effect of fat free cocoa powder drink consumption on antioxidative properties and proliferation activities of woman lymphocyte. Healthy woman subjects were divided into cocoa group (n = 9) and control group (n = 9). Cocoa powder drink containing skim milk and sugar was given to the cocoa groups every morning for 25 days. The control group received only water containing skim milk and sugar. Both cocoa and control group received physical medical checkup at the beginning and at the end of the intervention. Their peripheral blood was taken for lymphocyte antioxidant analysis. The measured antioxidant properties consisted of antiradical activity by DPPH method, malonaldehyde (MDA) and glutathione levels. The data of cocoa group showed that there was a significant increase (p ≤ 0.05) in antiradical level from 31+11.2 to 40.19+7.42% and glutathione from 48.2±10.5 to 66.7±15.9 μmol/land a decrease in MDA level in the lymphocyte (p < 0.05) from 2.98±2.21 to 1.29±0.33 μmol/las compared to the control group (from 25.77±6.9 to 26.79±6.12%; 34.7±20.7 to 37.8±19.2 μmol/land 3.01±1.53 to 2.069±0.707 μmol/l respectively) after consumption of the cocoa powder drink. The results of this research revealed that fat free cocoa powder has a strong antioxidant activity which was manifested up to the blood cells.
Penurunan Logam Berat dan Pigmen pada Pengolahan Geluring Rumput Laut Gelidium Sp. dan Ulva Lactuca Erniati Erniati; Fransiska Rungkat Zakaria; Endang Prangdimurti; Dede Robiatul Adawiyah; Bambang Pontjo Priosoeryanto
Jurnal Pengolahan Hasil Perikanan Indonesia Vol 21 No 2 (2018): Jurnal Pengolahan Hasil Perikanan Indonesia 21(2)
Publisher : Department of Aquatic Product Technology IPB University in collaboration with Masyarakat Pengolahan Hasil Perikanan Indonesia (MPHPI)

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Abstract

Rumput laut merupakan komoditi penting sebagai bahan pangan sehat. Geluring adalah produk pangan berbentuk lembaran kering, tipis dan berwarna hijau kecoklatan, dibuat dari campuran rumput laut Gelidium sp. dan Ulva lactuca. Tujuan penelitian ini adalah menentukan pengaruh proses pengolahan geluring terhadap kadar klorofil, karotenoid dan logam berat. Tahapan proses pengolahan geluring terdiri dari perendaman rumput laut kering, pengecilan ukuran, penghalusan, pembuatan bubur, penambahan bumbu, pencetakan dan pemanggangan. Pembutaan produk geluring terdiri dari P1: geluring tanpa bumbu, P2: geluring berbumbu dan P3: geluring berbumbu dan dipanggang, analisis bahan baku juga dilakukan pada rumput laut Gelidium sp. segar (GS) dan kering (GK), Ulva lactuca segar (US) dan kering (UK). Analisis terdiri dari analisis kadar klorofil, karotenoid dan residu logam berat pada produk geluring. Hasil penelitian menunjukkan bahwa pengolahan geluring berpengaruh nyata (P<0,05) terhadap penurunan jumlah klorofil a, klorofil b, klrorofil total, karotenoid dan pengurangan residu logam berat. Kadar klorofila, klorofil total dan karotenoid tertinggi terdapat pada geluring P1 dengan nilai 0,60 mg/g, 1,06 mg/g dan 0,23 mg/g, sedangkan kadar klorofil b geluring P1 dan P2 mempunyai nilai yang sama (0,46 mg/g). Residulogam berat Pb dan Cd geluring P1, P2 dan P3 yaitu Pb<0,001 mg/kg dan Cd<0,02 mg/kg. Nilai ini jauh lebih rendah dibandingkan residu Pb dan Cd pada bahan baku Ulva lactuca kering dan Gelidium sp. kering yaitu pada kisaran 1,18-5,71 mg/kg. Proses pengolahan geluring mengurangi kadar klorofil dan karotenoid, akan tetapi bermanfaat untuk menurunkan residu logam berat pada produk olahan rumput laut.
PAT-3 In Vitro Growth Inhibition Activities of Natural (nCaIFN) and Recombinant (rCaIFN) Canine Interferons on Three Different Tumor-Derived Cell Lines Bambang Pontjo Priosoeryanto; Rizki Rostantinata; Eva Harlina; Lina Noviyanti
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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Recently, from many kinds of diseases one could be counted is a tumor disease. Tumor is a degenerative disease that involved many biological pathways within the host. A tumor or neoplasm can be defined as a disturbance of growth characterized by excessive, abnormal and uncontrolled proliferation of transformed or altered cell(s) at  one or more primary points within the host, and frequently at  one or more metastatic sites (Priosoeryanto, 1994).The treatment of tumor is mostly by medical surgery which usually combined with chemotherapeutic agent(s), unfortunately the using of chemotherapeutic agent can develop a seriously side effect to the treated-patients. Biological substances like interferon (IFN) known as anti-virus agent is also one of promising candidate for treating or preventing of tumor disorders.Feline and canine squamous cell carcinoma is one of tumor type that often found in cat and dog, and mostly develop to a very aggressive disorder. The using of in vitro cell culture is a way to avoid the use of live animals on the study of tumors especially the study of antitumor agent due to can mimic the in vivo condition.  The aim of the present study is to examine the growth inhibition activity of natural and recombinant canine interferon in order to find the suitable biological substances for combating tumor disorder especially in the field of veterinary medicine and also as an information for the development of tumor treatment in the human medical side.
PCS-5 Nitric Oxide Induced Basal Cell Hyperplasia and Lamina Propria Elongation in Rat Gastroesophageal Junction Tena Djuartina; Bambang Pontjo Priosoeryanto; Ari Fahrial Syam; Ahmad Aulia; Tri Isyani Tungga Dewi
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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NO (Nitric Oxide) is an inorganic compound composed of nitrogen and oxygen, NO is also produced in various places on various types of mammalian cells. NO as a radical compound is important in mediating physiological and pathological events in mammals including humans [1].GEJ (gastroesophageal junction) is a transition zone between the surface of esophagus which is covered by stratified squamous epithelium to the gastric mucosa which consists of simple columnar epithelium (z-line), where circular muscle of esophagus fuse with oblique muscle and lipid layer of the gaster. At the lower part of GEJ, there is the lower esophageal sphincter (LES) that not only allow food to move into stomach and works as an exit passage of the gas, but also inhibit reflux of any substances that potentially can cause harm to the esophagus [2].Petersson et al, found that chronic exposure to cytotoxic levels of NO can cause inflammation, intestinal metaplasia and neoplasia. Although it is known that gastric acid, pepsin and bile acids can cause adenocarcinoma of distal esophagus and GEJ, NO exposure and nitrosative stress role in this phenomenon is yet to be fully understood and further study is needed [3].The purpose of this was to identify and compare the histopathological changes occurring in GEJ in relation to administration of physiological concentration of nitrate dissolved in HCl and ascorbic acid. As such, the animal model used in this study can be used to study and represent the changes microscopically, because obtaining a full thickness biopsy from a human subject can be difficult to perform.
JSPS-9 Microbiologial Quality of Chicken Carcasses in Bogor Indonesia Based on Campylobater sp. and Salmonella sp. Counts Herwin Pisestyani; Elisabet Tangkonda; Maya Shofa; Surachmi Setyaninigsih; Denny Widaya Lukman; Bambang Pontjo Priosoeryanto; Naoaki Misawa
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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Abstract

Unhygienic handling chicken carcasses during slaughtering until selling to costumers can lead to contamination by pathogenic bacteria such as Campylobacter sp., and Salmonella sp. entering human’s body can cause foodborne diseaseThe aims of this study were to detect contamination and enumuration of Campylobacter sp, and Salmonella sp. in chicken carcasses from poultry slauhterhouses and markets in Bogor Indonesia.
PAT-8 Antiproliferation Activity of Keladi Tikus (Typhonium flagelliforme) Leaves Ethanol Extract on MCA- B1 and MCM-B2 Tumor – Derived Cell Lines In Vitro Riski Rostantinata; Bambang Pontjo Priosoeryanto; Eva Harlina; Waras Nurcholis; Lina Noviyanti; Rachmi Ridho
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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Abstract

INTRODUCTIONTumor  is  a  degenerative disease  as  the second agent cause of death in human. This disease is caused by disturbances of cell’s growth that show alteration and uncontrolled of cells proliferation. The uncontrolled of cells proliferation is also accompanied by penetration of that cells into others tissue and develop on it. Removed of tumor is usually done by operation or chemotherapy. Alternative treatment that can be used is herbal treatment. Typhonium flagelliforme known as “Keladi Tikus” in Indonesia; is known has a chemopreventive effect (2). Other researchers also show flavonoid glucoside of T. flagelliforme (1) can induce the activity of apoptosis in colon cancer cells (5). The aim of this study is to examine the in vitro anti-proliferation activity of Typhonium flagelliforme leaves ethanol extract on MCA- B1and MCM-B2 cell line.
Message from Orginizing Committee Bambang Pontjo Priosoeryanto
Hemera Zoa Proceedings of the 20th FAVA & the 15th KIVNAS PDHI 2018
Publisher : Hemera Zoa

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Dear Colleagues,     It gives us immense pleasure to inform you that Indonesian Veterinary Medical Association (IVMA) is organizing the 20th Federation of Asian Veterinary Associations Congress (FAVA Congress) & the 18th Indonesian Veterinary Medical Association Congress (IVMA Congress) an International Congress, Seminar and Workshop. The event will be held in the Nusa Dua, Bali, the very famous paradise island and international tourist destination from October 30th to November 3rd, 2018.     The current congress will be enriched and compose of several satellite meeting of international and national veterinary organizations such as The 40th FAVA Council Meeting, 15th IVMA International Veterinary Scientific Conference and Animal Health Expo, The 2nd JSPS Core-to-Core Program Tripartite Meeting, The 1st FAVA-AVA Joint Meeting, ASEAN Veterinary Statutory Body Network (AVSBN) Meeting, Meeting of IVMA's Organizations of Veterinary Specialty and Scientific Interest Groups, Indonesian Animal Hospital Association (ARSHI) Meeting and the 16th PIDHI Meeting. It is expected to be a big event in veterinary field in 2018 with expected more than 1,000 participants coming around the country as well as foreign participants from Asian countries and other continents.     In this opportunity, a very basic Veterinary Role as an important profession was chosen as the theme of the present event “To Serve Mankind through Animal Kingdom”. The Organizing Committee cordially invites all the Veterinarian, Veterinary and Biomedical Scientists, Animal Husbandry practitioners, Human Medical, Academicians, Scholars and other related professions in Asia and other continents to take part in this event.     The Congress and Scientific seminar will focus on the improvement of the role of veterinary professions in Asian countries as well as recent developments, trends and technologies available for disease prevention, diagnosis, treatments as well as productivity and quality of animals and animal products. The main objective of this event is to bridging government-academicians–business sector and public participation to achieve the goal for better serve and better quality of life. Thank you.Sincerely, Bambang Pontjo Priosoeryanto, Chairman of the Organizing Committee
AH-35 Potence for Osteogenesis of (Cissus quadrangularis Salisb) Ekstract in Ovariectomized Rats Mustafa Sabri; Nurhidayat Nurhidayat; Wasmen Manalu; Bambang Pontjo Priosoeryanto; Hamny Hamny; Sri Wahyuni
Media Veteriner Proceedings of The 5th Congress of Asian Association of Veterinary Anatomists (Asian AVA) 2015
Publisher : Media Veteriner

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Abstract

Potence for Osteogenesis of (Cissus quadrangularis Salisb) Ekstract in Ovariectomized Rats
PENGARUH STEROL LEMBAGA GANDUM (Triticum sp.) TERHADAP PROFIL LIPIDA DARAH TIKUS Sri Anna Marliyati; Hidayat Syarief; Deddy Muchtadi; Latifah Darusman; Rimbawan Rimbawan; Bambang Pontjo Priosoerjanto
Media Gizi dan Keluarga Vol. 28 No. 2 (2004): Media Gizi dan Keluarga
Publisher : Media Gizi dan Keluarga

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Abstract

ABSTRACT. The role of fitosterol in preventing cholesterol absorption and reducing atherosclerosis risk has been reported. This research was conducted to evaluate the effect of wheat germ sterol on the concentration of total cholesterol, LDL, HDL, triglycerides, and lesion formation in mice. In this research work. Sprague Dawley mice at the age of 2 months  (productive age) were used A random block design was employed with the following treatment on each experimental unit: Po (basal diet, negative contra/), PI (basal diet with cholesterol added, positive control), P2 (basal diet with cholesterol and ground wheat germ added), P3 (basal diet with cholesterol and wheat germ oil added). P4 (basal diet with cholesterol and wheat germ sterol added). 'and P5 (basal diet with cholesterol and wheat germ sterol supplemented margarine). Each mouse was d.esigned to intake 0.0343 g ofsterol daily, except those of negative control (Po) and positive control (PI). In order to increase cholesterol concentration in blood serum ofmice, 20 mglkg-body weight per day ofpropyltiourasil (PTU) was added into each diet. A set oftests was carried out to observe the concentrations of total cholesterol. LDL, HDL, and tryglycerides in blood serum of test animals, and mouse aorta micrographs. Results showed that wheat germ sterol could prevent the increase ofcholesterol in the blood ofmice. Feeding with sterol (P4) or sterol-supplemented margarine (P5) prevented the increase of total cholesterol after I month of experimentation, however, only P4 sustained the same condition after 2 months ofexperimentation. Feeding with wheat germ sterol (P4) was also the only treatment that prevented the increase of LDL cholesterol after 2 month of experimentation, and it was not different significantly with negative control (Po). Results of experimentation also showed that the concentration of HDL in serum blood of mice was not affected by wheat germ sterol. Unsurprisingly, there was no lesion ofatherosclerosis observed in all treatments used in this research. This result confirmed that mouse is resistant to atherosclerosis. Keywords: wheat germ sterol, mouse, total cholesterol, LDL, HDL, triglycerides. atherosclerotic lesions
Co-Authors . CHURIYAH . Darmawi Adhi Rahmat Hariyadi Aditya Primawidyawan Agus Susanto Ahmad Aulia Ahmad Aulia Andra Hendriarto Andri Hardianto Andri Lubis Andri Prasetiyo Anggraeny Putri Sekar Palupi Anggraini, Lutvi Anissa Canintika Anita Esfandiari Annisa Fitriyana Ardi Sandriya Ari Fahrial Syam Ari Fahrial Syam Aria Kekalih Asri, Lia Amelia Tresna Wulan Aulia Andi Mustika Azhari Azhari Bambang Sunendar Purwasasmita, Bambang Sunendar Bayu Febram Bayu Febram Bayu Febram Prasetyo Benny Syariefsjah Latief Bethy Suryawathy Hernowo Betty S.L. J Betty Sri Laksmi Jenie Budi Arifin Chudahman Manan Chudahman Manan Dahlia Sutanto Daldiyono Daldiyono Daldiyono Daldiyono Dara Juliana Deddy Muchtadi Dede Robiatul Adawiyah Deni Noviana Denny Widaya Lukman Dewi Fatma Suniarti Dewi Ratih Agungpriyono Djarot Sasongko Hami Seno Dwi Kesuma Sari Dyah Sulistyani Rahayu Edy Djauhari Purwakusumah Eka Nurul Qomaliyah Endang Prangdimurt Endang Prangdimurti Endang Sjamsudin Erniati, Erniati Esti Mumpuni Eva Harlina Evy Damayanthi Fachriyan Hasymi Pasaribu Fachrul Razi Fadila Raisyadikara Farra Sasmita Franky Oscar Franky Oscar, Franky Fransiska R. Zakaria Fransiska Rungkat Zakaria Fransiska Rungkat Zakaria Gatot T. Mulyadi Gatot Trimulyadi Rekso Gunanati Soedjono Gunanti Gunanti . GUSTAF ADOLF WATTIMENA Hamny Sofyan Hartanti Hartanti Hartanti Hartanti, Hartanti Hasim Hasim Hatibie, Mendy Juniaty Hatta, Isnur Herwin Pisestyani Hidayat Syarief Husnawati, . I Made Kardena I Nyoman Suarsana I Nyoman Suartha I Wayan Gorda I wayan Teguh Wibawan IETJE WIENTARSIH Irmanida Batubara Iwan Harjono Utama Jimmy Pangihutan Juliana, Dara Kazuyuki Uchida Koeswinarning Sigit Komariah Komariah Kreshanti, Prasetyanugraheni Kuroki, Yutaka KUSMARDI KUSMARDI Lanniari, Nafrina Latifah Darusman Lilis Nuraida Lina Noviyanti Sutardi Lisni Noraida Lucky Riawan Lusi Epsilawati Madyastuti, Rini Mahdi Abrar Makmuri Yusuf Makmuri Yusuf MARIA BINTANG Maya Shofa Mieke Hemiawati Satari Mieke Hemiawati Satari Mieke Hermiawati Satari Miksusanti Miksusanti Mirnawati Soedarwanto Mirnawati Soedarwanto Monica Septiani Muharty, Annisya Najmah Najmah Nancy Dewi Yuliana Naoaki Misawa NASRIANTI SYAM, NASRIANTI Nina Kusumawati Nur Fathonah Sadek Nurhidayat - Nurhidayat, Nurhidayat Okabayashi, Tamaki Prangdimurt, Endang Priskila Priskila Putu Angga Wiradana Putu Eka Sudaryatma Rachmi Ridho Rahayu WoroWiranti Rahmadansah Rahmadansah Rahminiwati, Min Rahyussalim Ratna Puspita Rayendra, Raendi Retno Wulansari Rifki Septawendar Riki Siswandi Rimbawan , Rini, Dian Cipta Ripta Mustafa Nugraha Risa Tiuria Riski Rostantinata Riski Rostantinata Rizal Syarief Rizal Syarief Rizki Fitria Rizki Rostantinata Ros Sumarny Rostantinata, Riski Ryoji Yamaguchi Sabri Mustafa Sadek, Nur Fathonah Safrida Safrida Sajida Sajida Samuel Leonardo Silitonga SANTOSO CORNAIN Sarifah, Norlaila Sebayang, Shalina Septina Sabilla Lubis Shafiyyah Az Zahra SILMI MARIYA Slamet Budijanto Sri Anna Marliyati Sri Estuningsih Sri Kayati Widyastuti Subangkit, Mawar Sugeng Supriadi, Sugeng Sukasah, Chaula Luthfia Sunardhi Mangundjaja Sunardhi Mangundjaja, Sunardhi Surachmi Setiyaningsih Surachmi Setyaninigsih Surya Pangidoan Nasution Suryani Suryani Suryani Suryani Susi Susanah Susumu Tateyama Syamsudin Abdillah Takeshi Katayama Tangkonda, Elisabet Tena Djuartina, Tena Toshisada Suzuki Tri Isyana Tungga Dewi Tri Isyani Tungga Dewi Tungga Dewi, Tri Isyani Tutik Wresdiyati Ummu Balqis Vetnizah Juniantito Wahyuni, Sri Waras Nurcholis Wasmen Manalu Wati, Vivi Septya Weko Adhiarto Weko Adhiarto, Weko Yonathan Arderian Mantik Ziad Alaztha