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Suryani Suryani
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Journal : Medula

 1 
PREPARASI FENILBUTAZON DALAM PEMBAWA VESIKULAR ETOSOM DENGAN BERBAGAI VARIASI KONSENTRASI FOSFATIDILKOLIN DAN ETANOL Nur Illiyyin Akib; Suryani Suryani; Halimahtussaddiyah R Halimahtussaddiyah R; Niken Prawesti
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (392.986 KB) | DOI: 10.46496/medula.v2i1.243

Abstract

Phenylbutazone is non steroidal anti-inflammatory drug (NSAID) used  in treatment of joint inflammation such  as  rheumathoid  arthritis.  In  order  to  minimize  irritation  effect  on  gastrointestinal  tract,  the  dose  of phenylbutazone is reduced or administered through transdermal pathways. Flux penetration of drugs across the membrane  can  be  improved  by  using  vesicular  type  of  delivery  system  such  as  ethosome.  This  study  aim  to prepare  phenylbutazone in  ethosome  vesicular  system.  Ethosome vesicular  systems  were prepared  with  various concentrations  of  phosphatidylcholine  (2%  and  3%)  and  ethanol  (30%,  35%,  and  40%).  Vesicles  that  are formed  further  characterized  by  shape,  size  and  entrapment  efficiency.  The  shaped  of  ethosome  produced  is large  unilamellar vesicle.  The size of vesicle  varies  between  0.57 to 0.81  µm  with  the smallest size  on Formula C.  The  highest  entrapment  efficiencies  was  also  on  the  Formula  C  by  59.88%  with  2%  concentration  of phosphatidylcholine and 40% of ethanol. Keywords: phenylbutazone, vesicle, ethosomes.
UJI AKTIVITAS TABIR SURYA FORMULA SEDIAAN LOSIO EKSTRAK METANOL DAUN MANGKOKAN (Nothophanax scutellarium Merr.) Suryani Suryani; Rini Hamsidi; Nurlena Ikawati; Ahmad Zaeni; Hasnawati Hasnawati
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 2, No 1 (2014)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (277.548 KB) | DOI: 10.46496/medula.v2i1.245

Abstract

Leaves of mangkokan  (Nothophanax scutellarium Merr.) contain a potent antioxidant and sunscreen compounds. This plant potential to be developed into cosmetic products. One of cosmetic product that can be developed  using  natural  product  is  lotion.  This  research  aims  to  formulate  lotion  from  methanol  extracts  of leaves  mangkokan  and  determining  the  sunscreen  activity  of  lotion  with  various  concentration  of  the  extract 1%; 2.5%; 5%; 7.5%; and 10% using laboratory experimental design.  Preparation of mangkokan leaf extracts using methanol solvent by maceration method. Further tests conducted to determine the activity of sunscreen. Methanol extract of the leaves mangkokan then formulated to be lotion. Sunscreen activity of lotion was tested by  determaining  SPF  values.  Lotion  methanol  extract  of  leaves  mangkokan  resulting  the  highest  SPF  value contained in the methanol extract of the leaves mangkokan concentration of 10%. Keywords: mangkokan leaves, lotion, extract, lotion, sunscreen
Co-Authors Aat Sriati Abdul Hafid Ade Messy Indriani Afif D. Alba Afifah Nazla Sevina Afrinaldi Afrinaldi Agung Pramunarti Agus Sukirno Ahmad Zaeni Aida Safitri Aira Annastasya Alesia Lorenzza Sinaga Almasdi Syahza Andri Nugraha Anna Choirunnisa, Anna Anzora Anzora Aras Mulyadi Ari Handriatni Ary Prasetyawati Aryantiningsih, Dwi Sapta Asep Furqonuddin Asnel, Roza Aulia Dini Ayuningtias Ayu Juniarti BASUKI ARIANTO Bayu Azhar Cholida Azzahro Debi Rianti Dedi Afandi Dedy Mardiyansyah Derry Trisna Wahyuni S Desy Mariani Dewi Aya Sofia Dewi Novianti Dewi, Heni Aguspita Efri Widianti Elsa Fadilah Ema Dauyah Erina Erina Erina Septianti Etika Emaliyawati Fahrurazi Fahrurazi Fahrurrozi Fahrurrozi Fandi Rahman Feri Candra Fitri Raya Fitria Fitria Habsyah Saparidah Agustina Hafsah Nirwana Halimahtussaddiyah R Halimahtussaddiyah R hasanah hasanah Hasnawati Hasnawati Hawwa Nasywa Aqillah Hidayani Syam Imas Rafiyah Imelda Imelda Indarmien Netty Ariasih Indira Nahdaffa Rahma Iqbal Iqbal Iqfariana Iqfariana Irma Aryani Jely Isnaini Juanna Soehardy Julia Veronika Larasati Junaidi Abdillah Khairani Khairani Lia Anggresani Lia Novianty Lisa Ulandari Mahdi Abrar Mahdi Abrar Marufah Marufah Marwah Puspitasari Mas’ad Mas’ad Maulida Maulida Maulida Maulida Melan Susanty Meta Mahendradatta Mia Audina Musyadad Mohamad Syahroni Mohammad Kanzunnudin Muh. Fitrah Muhammad Asfar Muhammad Rifqi Muhammad Saleh Muhammad Sendi Muhammad Sukri Zaenal Muhammad Yassir Muhiddinur Kamal Mulyadi Mulyadi Musa Budiarta Gunawan Mustaqimah Nanik Wahyuni ‎ Nelli Roza Neni Heryani Niken Prawesti Ningsih, Kursiah Warti Nita Fitria Novira Kusrini Nugroho Nugroho Nur Fitriyana Nur Illiyyin Akib Nur Salsa Bella Nurilliyyin Akib Nurin Rochayati Nurlena Ikawati Nurmaela Mela Nurmaela Oswati Hasanah Pargito Pargito parlin, winda Pujiati Pujiati Purnama Ramadani Silalahi Purnama Ramadhani Silalahi Putri Ariani Rahmad Safitri Rahmi Pramulia FS Rastina Rastina Ratu Humaemah Restu Prihandini Widiar Ria Febrina Riadi Armas Rifa Nada Alfiyyah Rifah Arum Rina Rina Rini Hamsidi Rini Susiani Rinjani, Santi Rinny Meidiyustiani Riswita Syamsuri Rita Friyani Rizky Yulion Rugaya H. Serosero Rurry Septiani Saifuddin Saifuddin Salma Ummul Khair Sandra Aulia Mardikasari Santi Perawati, Sapria Ningsih Shafira Indriani Sharfinna Hafizah Shinta Dewi Sintaini Fi Sholiha Siti Rokhimah Siwi Nugraheni sofia afritasari SRI RAHAYU Sugiarti Sugiarti Suharti Suharti Supriadi Supriadi Supyan Supyan Suradi Suradi Syarifah Farissi Hamama Syarifah Farissi Hamama Tachta Khalil Tambunan, Khairina Taty Hernawaty Teuku Rihayat Titik Maryati vicky arfeni warongan Victor Palapessy W.TEDJA BHIRAWA Wanti Dewayani Wasiul Muarif Winaruddin Winaruddin Wirmie Eka Putra Wiwik Tiswiyanti Yani AF Bastian Yesita Ragil Yoga Saputra Yuli Suryanti Yulia Irvani Dewi Yulia Sukmiyanti Yulidar Yulidar Yusrizal Akmal Yusrizal Yusrizal Zainal Zainal Zihan Rahminabillah