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All Journal MEDIA KONSERVASI Biospecies Jurnal Pendidikan Biologi Undiksha Jurnal Natur Indonesia Biogenesis: Jurnal Ilmiah Biologi ZOO INDONESIA Jurnal Penelitian Pertanian Terapan Jurnal Belantara Jurnal Biologi Tropis Buletin Anatomi dan Fisiologi (Bulletin of Anatomy and Physiology) Gorontalo Journal of Forestry Research Jurnal Medika Malahayati Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Journal of Tropical Marine Science Jurnal Ilmiah Kesehatan Zoo Indonesia Buguh: Jurnal Pengabdian Kepada Masyarakat Jurnal Inovasi Pembangunan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Kesehatan Kusuma Husada Jurnal Sylva Lestari Jurnal Pengabdian Masyarakat Tapis Berseri The International Journal of Tropical Veterinary and Biomedical Research Journal of Pharmaceutical and Sciences. AMMA : Jurnal Pengabdian Masyarakat Scientica: Jurnal Ilmiah Sains dan Teknologi JUKEJ: Jurnal Kesehatan Jompa Joong-Ki Jurnal Perikanan Jurnal Riset Multidisiplin Edukasi Joong-Ki Jurnal Natur Indonesia IJIS Edu : Indonesian Journal of Integrated Science Education Forest and Nature JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Berita Biologi Analit: Analytical And Environmental Chemistry
Nuning Nurcahyani
Jurusan Biologi, Fakultas MIPA, Universitas Lampung
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POTENSI PRODUK ALAMI LAUT DARI EKSTRAK ETANOL Sargassum duplicatum DAN Padina australis SECARA SITOTOKSIK TERHADAP SEL HeLa Saputra, Yosi Dwi; Widiastuti, Endang Linirin; Berliana, Melisa Intan; Nurcahyani, Nuning
Berita Biologi Vol 23 No 1 (2024): Berita Biologi
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/beritabiologi.2024.661

Abstract

Salah satu penyebab utama kematian wanita Indonesia adalah kanker serviks. Pertumbuhan sel jaringan tubuh yang tidak terkendali yang berubah menjadi tumor adalah akar penyebab penyakit ini. Banyak peneliti sedang menyelidiki beragam bahan kimia alami dari habitat laut sebagai pilihan pengobatan antikanker karena pengobatan kanker serviks memiliki efek samping yang besar dan durasi pengobatan yang panjang. Makroalga merupakan salah satu organisme laut yang dapat berpotensi sebagai sumber obat alami untuk terapi kanker. Bahan aktif seperti flavonoid, alkaloid, saponin dan steroid berpotensi sebagai agen anti kanker yang diduga dapat mempengaruhi siklus sel dalam pertumbuhan kanker melalui mekanisme apoptosis. Penelitian ini bertujuan untuk menganalisis pengaruh senyawa bioaktif yang terkandung didalam ekstrak Sargassum duplicatum dan Padina australis terhadap sitotoksisitas sel kanker serviks, HeLa. Aktivitas sitotoksik terhadap sel HeLa dievaluasi dengan menggunakan metode WST-8 dengan variasi kosentrasi ekstrak etanol 62,5; 125; 250; 500; 1.000; dan 2.000 ppm. Hasil uji sitotoksik memperlihatkan bahwa ekstrak S. duplicatum dan P. australis memiliki aktivitas sitotoksik terhadap sel HeLa. Nilai IC50 Sargassum duplicatum dan Padina australis terhadap sel HeLa masing-masing sebesar 1.108,7 dan 681,1 μg/ml. Hasil penelitian mengindikasikan bahwa S. duplicatum dan P. australis mempunyai aktivitas sitotoksik melawan sel HeLa, sehingga dapat dijadikan sumber obat antikanker serviks.
Effect of Juice Berry Fruit (Antidesma bunius (L.) Spreng.) on Total Cholesterol Levels in Mice (Mus musculus Linnaeus, 1758) with Hypercholesterolemia: Pemberian Jus Buah Buni (Antidesma bunius (L.) Spreng) terhadap Kadar Kolesterol Total pada Mencit Jantan (Mus musculus Linnaeus, 1758) Hiperkolesterolemia Isnaini, Nurul; Nurcahyani, Nuning; Fithria Mumtazah, Dzul; Sutyarso
Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH) Vol. 12 No. 2 (2025)
Publisher : Department of Biology Faculty of Mathematics and Natural Sciences Universitas Lampung in collaboration with The Indonesian Association of Biology (PBI) Lampung Branch.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/j-bekh.v12i2.427

Abstract

Hypercholesterolemia is influenced by excessive fat consumption. To lower blood cholesterol levels, both drug and non-drug therapy can be carried out. One plant that has the potential to lower cholesterol levels is the buni plant (Antidesma bunius (L.) Spreng.). This study aims to determine the effect of buni fruit juice and the most effective juice concentration in lowering total cholesterol levels in hypercholesterolemic male mice. This study used a completely randomized design consisting of 5 groups, each repeated 5 times. The experimental animals were given a High Fat Diet (MDTL) containing propylthiouracil (PTU) at a dose of 1.8 mg/200g BW suspended in 2% Pure Grain Alcohol (PGA) and 10 mL/KgBW of quail egg yolk. The treatments consisted of a negative control (standard feed); a positive control (MDTL and 0.52 mg simvastatin); P1 (MDTL and 1 ml of 20% buni fruit juice); P2 (MDTL and 1 ml of 25% berry juice); and P3 (MDTL and 1 ml of 30% berry juice). Treatments P1, P2, and P3 were administered MDTL for 14 days, followed by berry juice for another 14 days. The results were total blood cholesterol levels. Data were analyzed using a one-way ANOVA followed by Duncan's test at a confidence level of α = 5%. The results showed that administration of 30% berry juice reduced total cholesterol levels in male mice with hypercholesterolemia.
Integrating Agroforestry and Aquaculture: Effects of Moringa oleifera Leaf Extract on Growth Performance of White Snapper (Lates calcarifer) Mefida, Lidya Ika; Nurcahyani, Nuning; Azizah, Enur; Sutyarso
Forest and Nature Vol. 2 No. 2 (2026): April
Publisher : Green Insight Solutions

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63357/fornature.v2i2.37

Abstract

The integration of agroforestry and aquaculture systems has been increasingly explored to improve resource utilization and support sustainable food production. This study evaluates the potential of moringa (Moringa oleifera), a multifunctional agroforestry species, as a feed supplement for white snapper (Lates calcarifer). An experimental study was conducted using a completely randomized design with four dietary treatments: 0% (control), 2.5%, 5%, and 7.5% moringa leaf extract supplementation, each with three replicates, over a 28-day rearing period. Growth performance, including absolute length and weight gain, specific growth rate (SGR), survival rate (SR), and feed conversion ratio (FCR), was measured. The results showed that fish receiving moringa-supplemented feed generally exhibited higher growth values compared to the control. The highest average weight gain was observed in the 5% treatment (9.28 g), while the highest SGR was recorded in the 2.5% treatment (4.79% day⁻¹). Survival rates in all supplemented treatments reached 100%, compared to 90% in the control group, indicating favorable culture conditions and no adverse effects of supplementation. FCR values across treatments remained above 2, suggesting relatively low feed utilization efficiency. This may be related to the carnivorous feeding characteristics of white snapper, which can limit the effective use of plant-based feed components. Water quality parameters, including temperature, pH, and dissolved oxygen, remained within acceptable ranges throughout the study. This study provides empirical evidence supporting the integration of agroforestry biomass into aquaculture feed systems. The use of moringa as a locally available, renewable resource contributes to circular nutrient flows, reduces reliance on imported feed ingredients, and promotes environmentally sustainable aquaculture practices. These findings advance the development of integrated agroforestry–aquaculture systems as resilient and eco-efficient production models in tropical regions.
PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT POTENTIAL OF EXTRACTS ETHANOL MACROALGAE Padina australis FROM TEGAL MAS ISLAND LAMPUNG Fatimah Alhafizoh; Endang Linirin Widiastuti; Nuning Nurcahyani; Ni Luh Gede Ratna Juliasih; Endah Setyaningrum
Analit : Analytical and Environmental Chemistry Vol. 9, No. 01 April (2024) Analit : Analytical and Environmental Chemistry
Publisher : Jurusan Kimia FMIPA Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/analit.v9i01.178

Abstract

In the seas of Lampung, a kind of brown macroalgae known as Padina australis is commonly seen.. Padina australis is widely used in the food industry as a gelling agent, emulsifier, thickener, stabilizer and also in the medical industry. The content of phytochemical compounds that can be developed as phytopharmaceutical agents is one of them as antioxidants. The aim of this study was to analyze the phytochemical content and potential antioxidant activity of the macroalgae Padina australis. The method used was extraction by maceration in 70% ethanol as a solvent. The phytochemical test was performed qualitatively by a color reagent test. The FTIR test was performed to analyze the functional groups of the active ingredients, while the antioxidant test used the DPPH (1,1-diphenyl-2-picrylhydrazil) method. The results obtained show that the ethanol extract of Padina australis contains chemical compounds such as saponins, steroids, tannins, alkaloids, and flavonoids. Padina australis extract shows its potential as an alternative source of natural antioxidant compounds because it is able to reduce free radicals with an IC50 value of 407.96 ppm, which is classified as very weak antioxidant activity. Further research needs to be done to obtain other concentration doses so as to get the best antioxidant activity results that can be developed clinically for health products.    
Pengenalan Sumber Daya Alam Dengan Kandungan Antioksidan Tinggi Dalam Rangka “Pencegahan Penyakit Degenaratif” Nuning Nurcahyani; Endah Setyaningrum; Endang L Widiastuti; Indriyani
AMMA : Jurnal Pengabdian Masyarakat Vol. 3 No. 11 : Desember (2024): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

This activity was carried out in Banjar Agung Udik Village, Tanggamus, Lampung. This activity aims to provide knowledge about the benefits of antioxidants from surrounding natural resources in order to increase awareness of the importance of health among the community to prevent degenerative diseases. Banjar Agung Udik village is an area rich in natural resources. Most of the people are vegetable and fruit farmers, gardeners, and raise fish in ponds to meet their daily needs. One of the weakness of the local community is that they still have limited knowledge about the importance of natural resources that are rich in antioxidants and are beneficial for health, namely as preventing degenerative diseases. Therefore, training on the benefits of antioxidants from surrounding natural resources is very necessary to increase awareness of the importance of health through preventing degenerative disease among the people of Banjar Agung Udik. With the addition of this training, the knowledge and insight of the Banjar Agung Udik village community regarding the introduction of natural resources with high oxidant content as a means of preventing degenerative disease has increased. Apart from that, people are able to explain the benefits of natural resources with high antioxidant content for preventing degenerative disease.
Pelatihan Pemanfaatan Tanaman Obat Untuk Peningkatan SDM Di Desa Banjar Agung Udik, Tanggamus, Lampung Nida Lidya Susanti; Endah Setyaningrum; Nuning Nurcahyani; Endang Linirin Widiastuti
AMMA : Jurnal Pengabdian Masyarakat Vol. 3 No. 11 : Desember (2024): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Community Service Program aims to provide training on using technology-based medicinal plants to improve human resources and the health of the Banjar Agung Udik village community, Tanggamus, Lampung. This activity will ultimately provide insight, knowledge, abilities, and skills to Banjar Agung Udik village residents in utilizing natural materials in the surrounding environment as health drinks. This work was conducted on Tuesday, August 6, 2024 at 08.00-12.00 WIB with targeted audience are teenagers, PKK members and men in Banjar Agung Udik village. In addition, village officials also attended this activity. The training activity began with preparing plan and dividing the tasks of the service team, preparing the tools and materials needed during the training, and determining the training schedule. The activity ended with socialization and direction on making healthy drinks based on local natural resources. The results of this activity showed that the community was enthusiastic and actively involved in participating in the health drink-making training. With ongoing training, participants are expected to have the knowledge and skills that can be used to improve the quality of health, and even support community economic needs.
Pengenalan Penyakit Leptospirosis Pada Ibu-Ibu Majelis Taklim Miftahul Jannah Kelurahan Labuhan Ratu Kecamatan Labuhan Ratu Bandar Lampung Endang Linirin Widiastuti; Yulianty; Nuning Nurcahyani; Sri Wahyuningsih
AMMA : Jurnal Pengabdian Masyarakat Vol. 4 No. 3 : April (2025): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Leptospirosis is a disease caused by the bacterium Leptoslira. Banteri that can be transmitted from animals to humans. The spread can be through the urine of infected animals Leptospirosis disease increases during floods. Labuhan Ratu urban village in Bandar Lampung is one of the urban villages affected by flooding during high rainfall. An understanding of this disease is needed by the community, especially members of Majelis Taklim Miftahul Jannah in Labuhan Ratu Village. This is to be more vigilant in dealing with floods. The pre-test results of the Community Service Participants were 63.37. The post-test results showed an increase with a score of 90. These results prove an increase in understanding of Community Service participants by 26.33 points. The existence of this service is expected that members of Majelis Taklim Miftahul Jannah, Labuhan Ratu Village can understand the knowledge about leptorspirosis disease and the information obtained can be disseminated to the community in Labuhan Ratu.  Translated with DeepL.com (free version)
Pembinaan Kreativitas Dan Potensi Seni Masyarakat Desa BanjarAgung Udik Melalui Teknik Ecoprint Nuning Nurcahyani; Primasari Pertiwi; Kusuma Handayani; Gina Dania Pratami
AMMA : Jurnal Pengabdian Masyarakat Vol. 4 No. 5 : Juni (2025): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

This activity was carried out in Banjar Agung Udik Village, Pugung District, Tanggamus Regency. The diversity of flora in Banjar Agung Udik Village creates great potential for the development of nature-based art and creativity. The use of natural materials for art and creativity will not only produce unique and aesthetic works of art, but also have high economic potential. One method that can be used is the ecoprint technique, so a deep understanding of the ecoprint technique, research on appropriate natural materials, and training for the local community are needed. The PKM activity was carried out in 2 stages, the first stage was the delivery of material through lectures and discussions, the second stage was a demonstration/practice of making patterned cloth with the ecoprint technique. The evaluation results showed an increase in the pre-test and post- test scores of 2.75 or 13.75%. The conclusion of this activity is that the knowledge, insight, and skills of the community in Banjar Agung Udik Village have increased, especially regarding the use of the ecoprint technique in making patterned cloth.
Peningkatan Kesadaran Masyarakat Pesisir Desa Hanura Terhadap Risiko Penyakit Malaria Melalui Pendekatan Partisipatif Endah Setyaningrum; Nuning Nurcahyani; M. Kanedi; Salman Farisi; Jeany Audina Suryaningkunti; Lisa Vegita; Febrian Cahyadi; Ainun Rizqi Indriani
AMMA : Jurnal Pengabdian Masyarakat Vol. 5 No. 4 : Mei (2026): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

The population of Indonesia is around 32%  still lives in districts/cities at risk of contracting malaria. In addition, there are 154 districts/cities that fall into the low endemic area strata, 31 moderate endemic areas and 23 highly endemic areas. Hanura Village, Pesawaran Regency is one of the villages in Lampung Province that is still classified as a malaria endemic area. Hanura Village is one of the coastal areas in Lampung Province that has a high potential for the spread of malaria. Humid environmental conditions, the presence of standing water, and lack of public awareness regarding prevention efforts make this area vulnerable to an increase in malaria cases. This community service aims to increase the understanding and awareness of the Hanura Village community about the risks of malaria and its prevention measures through a participatory approach that actively involves the community. Based on these problems, it is necessary to increase awareness of the coastal community in Hanura Village about the risks of malaria through a participatory approach. The activity is carried out in several stages, namely identifying problems with the community, socialization and discussions regarding malaria and its causative vectors, education on malaria control, the use of mosquito repellent plants, and healthy and clean living behaviors. Through participatory methods, the community becomes the main actor in designing and implementing solutions relevant to their local conditions. This activity was attended by 20 villagers consisting of hamlet heads, integrated health post (Posyandu) cadres, PKK cadres, and village staff. Based on the evaluation results of the written test at the beginning of the activity (pre-test) and the written test at the end of the activity (post-test) of this training, showed an increase in knowledge of 37.8%. This activity was deemed successful because it was able to increase the understanding and awareness of the coastal community regarding the risk of malaria. The participants who attended were very enthusiastic about participating in the series of trainings and provided positive responses that are expected to support efforts to reduce malaria cases in Hanura Village.
Co-Authors ., Priyambodo Abdullah Aman Damai Adelina, Maya Afrisa Herni Putri Agis Agita Agus Irawan Agus Irawan Agus Setiawan Agus Setiawan Agus Setyawan Ainun Rizqi Indriani Alhafizoh, Fatimah Alqoriani A, Ostarica Anak Agung Istri Sri Wiadnyani Andrian Dwi Atmanto Andrian Dwi Atmanto Andriani, Silvia Andriyani, Agista Antika Febiola Utami Apriliasari, Messy Ardiansyah, Budi Khoiri Ari Winata Findua Arief Darmawan Arofah, Nur Lailatul Asmiati Asmiati Asmiati Asmiati Ayu Ayssca Besty Prastiwy Ayu Ayssca Besty Prastiwy, Ayu Ayssca Ayu Meilani Ayu Nirarai Putri Azizah, Enur Azzuhdy, Afifah Nissa Badia Roy Ricardo Nababan Badia Roy Ricardo Nababan Bagus Susilo Putra Bainah Sari Dewi Bainah Sari Dewi Bainah Sari Dewi Bambang Hermanto Berliana, Melisa Intan Betta Kurniawan, Betta Bona Quinda Budi Santoso Christine Wulandari Dania Pratami, Gina Dasuki, Diva Rosa Nirwana DEDI CANDRA Dewi Ira Rahmawati Dewi Selvia Dharmawati, Verli Diah E. Anggraini Dzul Fithria Mumtazah Eko Agus Srihanto Elisa N. Fitriana Elizabeth D. Krismuniarti Elly L. Rustiati Elly Lestari Rustiati Emantis Rosa Emantis Rosa Emantis Rosa Endah Setyaningrum Endah Setyaningrum Endah Setyaningrum Endah Setyaningrum, Endah Endang L Widiastuti Endang L Widiastuti Endang L. Widiastuti Endang Linirin Widiastuti Endang Nurcahyani Enny Saswiyanti Ernawiati, Eti Etika Julitasari Evi Kurniawaty Faizatin Nadya Roza Fardhira, Zikra Fatimah Alhafizoh Favirusen Rosyking Lumbanraja Febrian Cahyadi Feni Ismiyati Fithria Mumtazah, Dzul Fredy Rahman Dani G. Nugroho Susanto Ganda Wisnu Putra Ganda Wisnu Putra Gina Dania Pratami Gina Dania Pratami Gina Dania Pratami, Gina Dania Gunardi Djoko Winarno Halimi, Sofwan Harianto, Sugeng Prayitno Hendri Busman Hendri Busman Hendri Busman Hendri Busman Hendri Busman Hendri Busman Hendri Busman Henny Indah Pertiwi Hidayat Hidayat Iffa Afiqa Khairani Indah Fitri Sari Indriyani Indriyani Indriyani Indriyani Irawan, Dimaz Jani Master jani master Jani Master, Jani Jeany Audina Suryaningkunti Jhons Fatriyadi Suwandi Juliasih, Ni Luh Gede Ratna Julyanto . Junaidi Junaidi Junaidi Junaidi Kanedi, M Kanedi, M. Khairunnisa, Indah Khasana, Devi Ardiyati Khatarina Septi Amelia Putri Khoirunisa Kurniawaty, Evi Kusuma Handayani Leni, Yusyam Linda Oktaviani Lisa Vegita Liza Angeliya Lumbanraja, Favirusen Rosyking Lumbanraja, Favorisen R M Kanedi M. Kanedi M. Kanedi M. Kanedi M. Kanedi Mardinata, Roly Mefida, Lidya Ika Mohammad Kanedi Muhammad Pazry Muhammad Rizqi Mukhtadin muhammad sarpin pratama Mumtazah, Dzul Fithria Mustofa Usman Ni Luh Gede Ratna Juliasih Nida Lidya Susanti Nismah Nukmal Nur Anita Suciyati Nur Lailatul Arofah Nurhasanah Nurhasanah Nurhasanah Nurhasanah Nurul Apriani Adinda Nurul Isnaini Oktariana, Putri Ostarica Alqoriani A. Pertiwi, Widya Ratna Primasari Pertiwi Priyambodo Priyambodo Priyambodo Priyambodo Puspa, Egita Windrianatama Puspita, Wana Putra, Bagus Susilo Puty Orlando Arismedi Qotrunnada Salsabila Rahmat Hidayat Riris Roiska Risdiyansyah . Risdiyansyah Risdiyansyah Rizki Agung Santosa Rochmah Agustrina Rohmawati Bareta, Ainun Roly Mardinata Ronald H. P. Panjaitan Rosa, Emantis RR. Ella Evrita Hestiandari Safitri, Dewi Restika Ayu Sahroni, Mizan Salman Farisi Samsul Bakri Saputra, Yosi Dwi Sarasati, Filia Septiadi, Luhur Septiani, Linda Septiya Reni Sibarani , Marsya Christyanti Silvia Andriani Siti Asiyah Sitopu, Romekardo Sri Wahyuningsih Sri Wahyuningsih Suci Natalia Sugeng P Harianto Sugeng P Harianto1 Sugeng P. Harianto Sugeng Prayitno Harianto Sumayyah Annida Susanto, G. Nugroho Susanto, Gregorius Nugroho Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Tugiyono Tugiyono Tugiyono Tugiyono Tunggul Van Roy Utoyo , Laji Utoyo, Laji Wamiliana WAWAN ABDULLAH SETIAWAN, WAWAN ABDULLAH Wida Witriani Widianningrum, Wahyu Widiarti Widiastuti, Endang Linirin Winarno, Gunardi Djoko Wulandari, Kartika Dwi Yosi Dwi Saputra Yulianty Yulianty Soeradji Yulianty Yulianty Yulianty Yulianty Yuyun Solihat Zen, Tresa Variyani