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All Journal Jurnal Akuakultur Indonesia ACTA VETERINARIA INDONESIANA Jurnal Primatologi Indonesia Jurnal Sain Veteriner Proceedings of Annual International Conference Syiah Kuala University - Life Sciences & Engineering Chapter Jurnal Ilmiah Mahasiswa Veteriner Jurnal Medik Veteriner Asian Journal of Agriculture Ovozoa: Journal of Animal Reproduction Narra J Jurnal Ilmiah Ilmu-Ilmu Peternakan Jurnal Kedokteran Hewan The International Journal of Tropical Veterinary and Biomedical Research Buletin Pengabdian Depik Jurnal Ilmu-Ilmu Perairan, Pesisir, dan Perikanan Jurnal Medika Veterinaria Jurnal Agripet Peternakan Abdi Masyarakat (PETAMAS)
Amalia Sutriana
Laboratorium Farmakologi Fakultas Kedokteran Hewan Universitas Syiah Kuala
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Earth & Planetary Sciences Education Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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Determination of estrus in Aceh cows based on the van Eerdenburg method Qathrinnada Ramadhana; Ginta Riady; Hafizuddin Hafizuddin; Cut Nila Thasmi; Erdiansyah Rahmi; Amalia Sutriana
Ovozoa: Journal of Animal Reproduction Vol. 11 No. 3 (2022): Ovozoa: Journal of Animal Reproduction
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ovz.v11i3.2022.103-108

Abstract

Accurate determination of estrus status in an animal based on an appropriate estrus detection method can guarantee the cows' pregnancy after mating. This study aims to determine the estrus status of Aceh cows using the van Eerdenburg estrus behavior scoring method. This study was conducted from 22 January to 12 February 2021, at the Technical Implementation Unit for Animals of the Faculty of Veterinary Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia. The sample used was eleven Aceh cows aged 4-6 years old. Parameters observed were the number of cows exhibiting signs of estrus using the estrus behavior scoring method. The accuracy of estrus detection was confirmed by palpation per rectum to detect the presence of uterine tone. By observing signs of estrus using the method studied, 90.9% (10/11) of the cows were determined to be in estrus. Confirmation by the presence of uterine tone showed a 100% accuracy rate. The most effective sign of estrus was the passivity of the cow when being ridden by another cow or bull. This study concluded that estrus status in local cows could be determined using the estrus behavior scoring of the van Eerdenburg method.
THE EFFECT OF WHOLE SEED (Barringtonia racemosa) WATER EXTRACT ON ERYTHROCYTE, HEMOGLOBIN AND HEMATOCRITE COUNT OF WHITE RAT (Rattus norvegicus) EXPOSED TO CIGARETTE SMOKE Dasrul, D; Aliya, Yayang Nuri Al; Sutriana, Amalia; Asmilia, Nuzul; Daud, Razali
Jurnal Kedokteran Hewan Vol 17, No 2 (2023): June
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v17i2.25424

Abstract

This study aims to determine the effect of Barringtonia racemosa seed extract on the number of erythrocytes, hemoglobin levels, and the percentage of hematocrit in white rats (Rattus norvegicus) exposed to cigarette smoke. A total of 25 white rats Wistar strain, aged 3-4 months, male, weighing 180-200 g, were randomly divided into 5 treatment groups, each group consisting of 5 rats. Positive control group (KP) without exposure to cigarette smoke and without administration of Barringtonia racemosa seed extract, negative control group (KN) exposed to cigarette smoke without administration of Barringtonia racemosa seed extract. Treatment groups P1, P2, P3 were exposed to cigarette smoke and given Barringtonia racemosa seeds with doses of 50, 100, and 150 mg/kg BW/day, respectively. The extract was administered orally for 30 days. Blood collection in all groups was carried out via the orbital vein using a hematocrit pipette after the rats had been sedated with 0.2 mL of ketamine. Erythrocyte, hemoglobin, and hematocrit values were calculated using a hematology analyzer. Data were analyzed using one-way pattern analysis of variance (ANOVA). The results showed that giving Barringtonia racemosa seeds at doses of 50, 100 and 150 mg/kg/day had a significant effect (P0.05) in increasing the values of erythrocytes, hemoglobin, and hematocrit of white rats exposed to cigarette smoke compared to the control group which was not given the extract. In conclusion, the administration of Barringtonia racemosa seed extract can increase the number of erythrocytes, hemoglobin levels, and the percentage of hematocrit exposed to cigarette smoke.
EFFECT OF SALINITY CHANGES ON METHIONINE CONTENT IN TIGER GROUPER JUVENILE (Epinephelus fuscoguttatus) Abbas, Muhammadar Abdullah; Abidin, Muchlisin Zainal; Putra, Dedi Fazriansyah; Firdus, Firdus; Batubara, Agung Setia; Sail, Asmawati Muhammad; Syafruddin, Syafruddin; Roslizawaty, Roslizawaty; Sutriana, Amalia; Aliza, Dwinna
Jurnal Kedokteran Hewan Vol 12, No 4 (2018): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v12i4.12363

Abstract

This study was conducted to determine the effect of water salinity changes on methionine content in tiger grouper juvenile (Epinephelus fuscoguttatus). A total of 2,560 tiger grouper juveniles were used and divided into five groups consist of 1 control group (without exposed to salinity changes) and 4 treatment groups. The salinity was changed every 2, 3, 4, and 6 hours in treatment A, B, C, and D, respectively. Salinity levels were changed during 24 hours by lowering salinity level from 32 psu to 22 psu. Twenty five of fish were collected from each treatment for methionine content analysis. Data were analysed using one way analysis of variance (ANOVA). The results showed that there was a decrease in methionine content in all treatments. A significant decrease (P0.05) of methionine content in treatment A, B, and C were observed after 20 hours (1.15%), 18 hours (1.27%), and 16 hours (1.24%), respectively. While at 0 hours (control), the methionine content was 2.02%. Methionine level in treatment D was not significantly different (P0.05) compared to control group. As conclusion, rearing the tiger grouper juvenile with salinity fluctuations every 6 hours did not lead to methionine deficiency.
EFFECTIVENESS OF THE FERMENTATIVE EXTRACT OF Lactobacillus acidophilus AS ANTIMICROBIALS AGAINST Aeromonas hydrophila Akter, Mst Nahid; Hashim, Roshada; Sutriana, Amalia; Mohd Nor, Siti Azizah
Jurnal Kedokteran Hewan Vol 12, No 4 (2018): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v12i4.11920

Abstract

The purpose of this study was to evaluate the in vitro and in vivo antimicrobial activity of the commercial Lactobacillus acidophilus (L. acidophilus) cells and cell free extract against Aeromonas hydrophila (A. hydrophila). The in vitro method was carried out using well diffusion method. For in vivo evaluation, the effect of L. acidophilus on the survival rate of Pangasianodon hypophthalmus (P. hypophthalmus) infected with A. hydrophila was evaluated. The well diffusion method showed a significant inhibition ability of L. acidophilus cells against A. hydrophila compared to the cell free extract. The inhibition diameters obtained with cells and cell free extract were 17.23 mm and 15.17 mm, respectively. P. hypophthalmus injected with L. acidophilus cells and cell free extract following challenged with A. hydrophila cells showed survival rate of 70% and 60% respectively, at 2-week post challenged. The gas chromatography-mass spectrophotometry (GC-MS) result revealed that a diverse of compounds was detected in both the L. acidophilus cells and cell free extract, among them the most abundant component was pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl), which showed a promising anticancerous activity and might be played a significant role in the recovery of the infectious P. hypophthalmus. The current study revealed that both cells and cell free extract of L. acidophilus have antimicrobial activity against A. hydrophila.
Effect of Storage Time of Epididymis at 5 oC on Spermatozoa Quality of Aceh Local Goat Hamdan, Hamdan; Panjaitan, Budianto; Sutriana, Amalia; Aliza, Dwinna; Rahmi, Erdiansyah
Jurnal Kedokteran Hewan Vol 4, No 2 (2010): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v4i2.9811

Abstract

The objective of this study was to evaluate the effect of storage time of epididymis at 5 oC on spermatozoa quality of Aceh local goat. This research was conducted at Reproduction Laboratory, FKH Unsyiah from May to June 2009. Nine epididymis from local goat at the age of 1.5-2.0 years were used in this study. The epididymis were collected from abattoir in Banda Aceh. The experimental design used in this study was completely randomized design with 3 treatments and 3 replications. Spermatozoa quality which consist of sperm concentration, motility, amount of life sperm, and sperm abnormality were examined after the collection of epididymis on day 0 (H-0), day 1 (H-1), and day 3 (H-3) post storage at 5 oC. Data were analyzed using one-way analyses of variance (ANOVA). The result showed that no significant difference (P0.05) seen in the spermatozoa quality after different storage time. The average of spermatozoa concentration on H-0, H-1, and H-3 were 318x107/ml, 282x107/ml, and 241x107/ml respectively. On the average, the percentage of spermatozoa motility on H-0, H-1, and H-3 were 82,272,75; 80,252,83; and 78,070,92%, respectively. Life spermatozoa observed on H-0, H-1, and H-3 were 82,292,71; 80,631,87; and 80,093,31%, respectively. Observation on spermatozoa abnormality showed that the average of spermatozoa abnormality on H-0, H-1, and H-3 were 7,230,27; 8,210,55; and 10,753,14%, respectively. It could be concluded that the spermatozoa quality were not affected by the storage time at temperature of 5 oC.
Characterization of Inhibin from Culture and Non Culture of Granulose Cells for Monoclonal Antibody of Inhibin Production Amiruddin, Amiruddin; Nizwan Siregar, Tongku; Sutriana, Amalia; Aliza, Dwinna; Armansyah, T.
Jurnal Kedokteran Hewan Vol 4, No 1 (2010): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v4i1.9789

Abstract

This study has long-term objectives to obtain immunogenic prototype that can be used to induce multiple ovulation in goats. Working steps of this study were begun with the collection of ovarium from goats, collection of granulose cells, culture of granulose and characterization of molecular weight and isoelectric point (pI) of inhibin protein of granulose cells obtained from culture and non-culture of granulose cells, and followed by preparation of monoclonal antibody toward inhibin. The results showed that inhibin isolated either from culture or non-culture of granulose cells produced a 32 kDa band. Molecular weight of inhibin was measured by Western Blot. The 32 kDa band of SDS PAGE product appeared on Western Blot result was inhibin molecules produced by granulose cells collected fom culture and non-culture of granulose cells that can be identified by Mab-inhibin. Product of IEF gel electrophoresis suggested that inhibin molecule collected from culture of granulose cells has no charge at isoelectric points ranging from 5-6, depends on its total amino acid composition.
UJI TOKSISITAS AKUT EKSTRAK ETANOL DAUN MALAKA (Phyllantus emblica) TERHADAP MENCIT (Mus musculus). (Acute Toxicity Test of Ethanolic Extract of Malaka (Phyllantus emblica) Leaves on Mice (Mus musculus)) TR, T. Armansyah; Indriany, Sudi; Sutriana, Amalia; Rosmaidar, Rosmaidar; Asmilia, Nuzul; Panjaitan, Budianto; Aliza, Dwinna; Hamdan, Hamdan
Jurnal Kedokteran Hewan Vol 10, No 2 (2016): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v10i2.5137

Abstract

ABSTRACT The aim of this research was to asses the acute toxicity of ethanolic extract of malaka leaves using lethal dose 50 (LD50) on mice (Mus musculus). Twenty male mice weighing between 20-30 g were randomly divided into 4 groups (group K1-K4) of 5 mice each. All mice in group K1, K2, K3, and K4 were administered ethanolic extract of malaka leaves with the dose of 2, 4, 8, and 16 g/kg bw, respectively. Single dose of ethanolic extract of malaka leaves were given by oral gavage prior to clinical observation . The observation period was 14 days post administration, for sign of toxicity symptom, weight loss, and mortality. The result showed that no mortality was observed in the experimental animals during this study. Slight reduction of body weight was observed in group K2, K3, and K4, and no toxicity sign was found during fourteen days of observation. The LD50 of ethanolic extract of malaka leaves was higher than 16 g/kg body weight, thus, the substance was practically non toxic substance.
THE USE OF CASSAVA LEAVES AS A DIETARY COMPONENT FOR AFRICAN CATFISH FRY Sutriana, Amalia
Jurnal Kedokteran Hewan Vol 1, No 2 (2007): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v1i2.3128

Abstract

An experiment was carried out to evaluate the effect of graded levels of cassava leaf meal (CLM) with varying cyanide content on growth performance of African catfish (Clariasgariepinus) fry. There were four groups of fish, each comprising 12 fish per group. One groupwas fed on a control diet (0 mg HCN/kg diet) with fish meal (FM) and soybean meal (SBM) asprotein source (30% CP). Groups two, three and four were fed graded levels of CLM to replace10, 20, and 30% of the total diet at the expense of SBM which contains 4.19, 7.47 and 11.96 mgHCN/ kg diet respectively. After 12 weeks, fish fed with increasing level of CLM showed asignificant growth depression and poor feed utilization compared to those fed the control diet.Apparent dry matter digestibility (ADMD) and apparent protein digestibility (APD) were alsosignificantly (P0.05) affected by cassava leaf meal inclusion, with the best values were found infish fed the control diet (52.26+0.24% and 83.11+1.17% for ADMD and APD respectively). Bodycomposition of fish fed higher CLM tended to have less protein and fat but more ash. The poormethionine availability as a result of low protein digestibility and the presence cyanide contentlimits the use of CLM in African catfish fry diet.Keywords: African catfish, cassava, growth, cyanide
Perbedaan Viskositas Mucous Serviks dan Tipologi Ferning pada Sapi Aceh Repeat Breeding dan Fertil Thasmi, Cut Nila; Herrialfian, Herrialfian; Husnurrizal, Husnurrizal; Hafizuddin, Hafizuddin; Sutriana, Amalia; Dasrul, Dasrul; Titit, Marcelus Ferdinandez; Reza, Muhammad
Jurnal Agripet Vol 24, No 1 (2024): Volume 24, No. 1, April 2024
Publisher : Faculty of Agriculture

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17969/agripet.v24i1.34687

Abstract

ABSTRAK. Efisiensi reproduksi ternak sangat ditentukan berdasarkan deteksi estrus. Terdapat beberapa indikator estrus yang dapat dijadikan patokan deteksi estrus diantaranya keluarnya mucous serviks. Mucous serviks akan diamati sifat fisiknya diantaranya warna, (tampilan), konsistensi (viskositas), elastisitas, tipologi ferning dan pH. Pengamatan terhadap nilai viskositas dan tipologi ferning mucous serviks dibagi menjadi dua faktor utama dalam penelitian ini. Penelitian ini bertujuan untuk mengetahui perbedaan viskositas mucous serviks dan tipologi ferning pada sapi Aceh repeat breeding dan sapi Aceh fertil. Dalam penelitian ini digunakan 10 ekor sapi Aceh, terdiri dari 6 ekor sapi fertil dan 4 ekor sapi repeat breeding berumur 3-5 tahun yang telah disinkronisasi dengan prostaglandin F2 alpha (PGF2) sebanyak 5 mL secara intra muskulus dengan pola penyuntikan tunggal. Penentuan viskositas mucous serviks diukur berdasarkan nilai spinnbarkeit yang dideteksi pada saat puncak estrus. Untuk menentukan tipology ferning, mucous serviks dioleskan di atas objek glass, lalu dikeringkan selanjutnya diamati di bawah mikroskop. Tipologi ferning diklasifikasikan berdasarkan kriteria tipikal, atipikal, dan nihil. Data yang diperoleh dianalisis secara deskriptif dan uji T. Hasil penelitian menunjukkan terdapat tidak ada perbedaan viskositas mucous serviks, namun terlihat adanya perbedaan tipology ferning antara sapi Aceh repeat breeding dan fertil.(Differences in cervical mucous viscosity and ferning typology in repeat breeding and fertile Aceh cows)ABSTRACT. Reproductive efficiency of livestock is determined based on estrus detection. There are several indicators of estrus that can be used as a benchmark for estrous detection, including cervical mucous discharge. Cervical mucus will be observed for its physical properties including color, (appearance), consistency (viscosity), elasticity, ferning and pH. Observation of the viscosity value and typology of cervical ferning mucous was divided into two main factors in this study. The purpose of the study was to identify the variations in mucous cervical ferning between fertile Aceh cattle and repeat breeding. In this study, 10 Aceh cattle were used, consisting of 6 fertile cattle and 4 repeat breeding aged 3-5 years which had been synchronized with 5 mL of prostaglandin F2 alpha (PGF2) intramuscularly with a single injection pattern. The determination of cervical mucous viscosity is measured based on the spinnbarkeit value detected at the peak of estrus. To determine the ferning typology, cervical mucous was applied to the glass object, allowed to dry, and then examined under a microscope. Ferning typology was classified based on the criteria of typical, atypical, and nil. The data obtained were analyzed descriptively and T-test. The results showed that there was no difference in cervical mucous viscosity, but there was a difference in ferning typology between repeat breeding and fertile Aceh cows.
Klinik Hewan Keliling Rumah Sakit Hewan Pendidikan Prof. Noerjanto Universitas Syiah Kuala [Mobile Veterinary Clinic of Prof. Noerjanto Hospital Teaching Veterinary Hospital of Universitas Syiah Kuala] Sayuti, Arman; Panjaitan, Budianto; Syafruddin, Syafruddin; Adam, Mulyadi; Thasmi, Cut Nila; Roslizawaty, Roslizawaty; Rosmaidar, Rosmaidar; Siregar, Tongku Nizwan; Armansyah, Teuku; Sutriana, Amalia; Aliza, Dwinna
Buletin Pengabdian Vol 4, No 2 (2024): Bull. Community. Serv.
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/bulpengmas.v4i2.37290

Abstract

The long-term purpose of this community service is to support the autonomy of the university through independent income generation and to encourage the development of a culture of utilizing university research results for the community through the mobile veterinary clinic business carried out by Prof. Noerjanto Teaching Veterinary Hospital. To achieve above objectives, it was necessary to modify the existing clinic vehicle to include an operating room, mini-laboratory and pharmacy. The implementation of activities was carried out for five working days a week, by actively visiting smallholder livestock centers per village per day in the Aceh Besar areas. Services provided included livestock health consultation, treatment, vaccination (an effective measure as a form of protection for animals, synchronization of heat and artificial insemination, and assistance during birth. The diagnosis methods utilize the latest techniques, namely diagnosis and therapy techniques used in the field of veterinary medicine, which were the results of previous research. Mobile Clinic of Prof. Noerjanto's Teaching Veterinary Hospital had been modified by providing an operating table, mini laboratory, pharmacy, and repainting the car, thus increased the attractiveness of the community during the activities were carried out. Mass treatment of livestock in Aceh Besar district had reached the target which services covered five sub-districts. In conclusion, the mobile veterinary clinic in 2017 has successfully modified the clinic car and provided health services in 5 sub-districts in Aceh Besar District.
Co-Authors Abbas, Muhammadar Abdullah ABDELBAGI, MOHAMMED AHMED ELSHAREF Abdul Harris Abdullah A. Muhammadar Abidin, Muchlisin Zainal Aftari, Nailul Ahmad Baihaqi Ahsan, Muhammad Maulana Aini, Hanipah Aisyah Fadillah Tunnisa Ajirni Ajirni Akter, Mst Nahid Aliya, Yayang Nuri Al Amiruddin Amiruddin Amiruddin Amiruddin Annisa Anwar Sitorus Anwar Anwar Arman Sayuti Arman Sayuti Arman Sayuti Arman Sayuti Asmawati Asmawati Azzahra, Putri Batubara, Agung Setia budianto panjaitan Budianto Panjaitan Budianto Panjaitan Budianto Panjaitan Budianto Panjaitan Budianto Panjaitan Cut Nila Thasmi Cut Nila Thasmi, Cut Nila D Dasrul Darmawi Darmawi Dasrul Dasrul Dasrul, D Dedi Fazriansyah Putra Dian Masyitha Dwina Aliza Dwinna Aliza Dwinna Aliza Dwinna Aliza Elza Savitri Erdiansyah Rahmi Erdiansyah Rahmi Erdiansyah Rahmi Erina Erina Erina Erina Fakhrurrazi Fakhrurrazi Fakhrurrazi Fakhrurrazi Farid Wajidi Farida Farida Feby Fema Amzani Nasution Firdus Firdus Firdus Firdus Fuza Khoiriah Gani, Azhari Gholib Gholib, Gholib Ginta Riady Ginta Riady Hafizuddin Hafizuddin Hafizuddin Hafizuddin HAFIZUDDIN, UMAR PUTEH Hamdan Hamdan Hamdan Hamdan HANUM, FARAH FARIDA Hasan, Denny I. Henni Vanda HENNIVANDA HENNIVANDA Herrialfian . Herrialfian, Herrialfian Husnurrizal . Husnurrizal, Husnurrizal Indriany, Sudi Ismail Ismail Iwan Hasri Juli Melia Juli Melia KARTINI ERIANI Karunita Dewi Khairan Khairan Mada Admi Mahdi Abrar Masda Admi Mentari Azhari L Mira Ayu Lestari Hasibuan Mohd Nor, Siti Azizah Mst Nahid Akter Muchlisin Zainal Abidin Mudatsir Mudatsir Muhammad Ammar Muhammad Hambal Muhammad Hambal Muhammad Hanafiah Muhammad Hanif Muhammad Isa Muhammad Reza Mulyadi Adam Mulyadi Adam, Mulyadi Nada Sarah Syahputri Nazaruddin Nazaruddin Nazaruddin Nazaruddin Novianti, Arindita Niatazya Nurhazimah Nurhazimah Nurliana NURLIANA NURLIANA Nuzul Asmilia Nuzul Asmilia Nuzul Asmilia Putra, Dedi Fazriansyah Qathrinnada Ramadhana R Roslizawaty R Roslizawaty, R Rahmad Rahmad Rasmaidar . Raysa Syarifah Razali Daud Razali Daud rina aulia barus Rinidar Rinidar Roshada Hashim Roshada Hashim Roslizawaty Roslizawaty Roslizawaty Roslizawaty Roslizawaty Roslizawaty, Roslizawaty Rosmaidar Rosmaidar Rosmaidar Rosmaidar, Rosmaidar Rossy Septia Putri S Syafruddin Sail, Asmawati Muhammad Sari, Wahyu Eka Sembiring, Rinawati Siddik, Tasya Luthfiah Siregar, Tongku N. Siti Aisyah Siti Azizah Mohd Nor Sri Wahyuni Sri Wahyuni Sriyanti, Cut Sudi Indriany Sugito Sugito Syafruddin Syafruddin Syafruddin Syafruddin Syafruddin Syafruddin Syafruddin, S T Armansyah TR T. Armansyah T. Armansyah T. Armansyah Teuku Armansyah Teuku Armansyah Titit, Marcelus Ferdinandez Tongku N. Siregar Tongku Nizwan Siregar Tongku Nizwan Siregar Tongku Nizwan Siregar Tongku Nizwan Siregar, MP Triva Murtina Lubis Winaruddin Winaruddin Yayang Nuri Al Aliya Yusmadi Yusmadi Zakwan, Muhammad