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All Journal HAYATI Journal of Biosciences Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Jurnal Gizi dan Pangan Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan ACTA VETERINARIA INDONESIANA Jurnal Pengolahan Hasil Perikanan Indonesia Hemera Zoa Media Veteriner Media Gizi dan Keluarga Jurnal Sain Veteriner VALENSI Jurnal Veteriner JURNAL KIMIA SAINS DAN APLIKASI Microbiology Indonesia Dentika Dental Journal Pharmaciana: Jurnal Kefarmasian Jurnal Kesehatan Masyarakat Medical Journal of Indonesia Current Biochemistry Majalah Obat Tradisional Padjadjaran Journal of Dentistry Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Justek : Jurnal Sains Dan Teknologi AGROSAINSTEK: Jurnal Ilmu dan Teknologi Pertanian ARSHI Veterinary Letters Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan JURNAL PANGAN Jurnal Ilmu Kefarmasian Indonesia Jurnal Jamu Indonesia Jurnal Pembelajaran dan Biologi Nukleus Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI) The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Kedokteran Hewan Molekul: Jurnal Ilmiah Kimia Jurnal Veteriner dan Biomedis Borneo Journal of Pharmacy Journal of Natural Product for Degenerative Diseases Indonesian Journal of Jamu Jurnal of Syiah Kuala Dentistry Society
Bambang Pontjo Priosoeryanto
Divisi Patologi, Sekolah Kedokteran Hewan Dan Biomedis, IPB University, Bogor, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Veterinary Other

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PERANAN HEMAGLUTININ Staphylococcus aureus DALAM PROSES ADHESI PADA SEL EPITEL AMBING SAPI PERAH Abrar, Mahdi; Wibawan, I Wayan Teguh; Priosoeryanto, Bambang Pontjo; Soedarwanto, Mirnawati; Pasaribu, Fachriyan Hasymi
Jurnal Kedokteran Hewan Vol 7, No 1 (2013): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v7i1.564

Abstract

Tujuan penelitian ini adalah mengetahui kemampuan hemaglutinin pada Staphylococcus aureus (S. aureus) dalam proses adhesi. Uji adhesi pada sel epitel ambing dilakukan dengan menggunakan metode Velentine-Weiggand. Hasil penelitian ini menunjukkan bahwa S. aureus yang memiliki hemaglutinin menunjukkan kemampuan adhesi yang jauh lebih baik (380 bakteri/20 sel) dibandingkan dengan yang tidak memiliki hemaglutinin (56 bakteri/20 sel).
ISOLASI DAN KARAKTERISASI HEMAGLUTININ Staphylococcus aureus PENYEBAB MASTITIS SUBKLINIS PADA SAPI PERAH Abrar, Mahdi; Wibawan, I Wayan Teguh; Priosoeryanto, Bambang Pontjo; Soedarwanto, Mirnawati; Pasaribu, Fachriyan Hasymi
Jurnal Kedokteran Hewan Vol 6, No 1 (2012): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v6i1.347

Abstract

Dalam penelitian ini isolasi dan karakterisasi hemaglutinin Staphylococcus aureus dilakukan dengan teknik afinitas kromatografKarakterisasi hemaglutinin yang dihasilkan dilajutkan dengan teknik elektroforesis menggunakan metode sodium dodecyl sulphate gelelectrophoresis (SDS-PAGE) dan dilanjutkan untuk melihat pengaruh suhu dan enzim terhadap aktivitas hemaglutinin. Hasil penelitiamenunjukkan bahwa komponen hemaglutinin Staphylococcus aureus yang telah diisolasi memiliki berat molekul 46 kDa. AktivitStaphylococcus aureus dalam meghemaglutinasi hilang pada pemanasan 60 C dan pengaruh enzim proteolitik. Hasil ini mengindikasikabahwa hemaglutinin Staphylococcus aureus adalah protein.
Optimization of Cardamom Fruit (Amomum compactum) Extraction Focused on Total Terpenoid Extraction and Cytotoxic Activity Using Response Surface Methodology Juliana, Dara; Priosoeryanto, Bambang Pontjo; Nurcholis, Waras
Jurnal Jamu Indonesia Vol. 8 No. 2 (2023): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v8i2.328

Abstract

Cardamom is one of the medicinal plants called perennial herbs from the Zingiberaceae family. Cardamom, with the scientific name Amomum compactum, contains various phytochemical compounds such as terpenoids, flavonoids, phenolics, tannins, sterols, and proteins that are pharmacologically useful as an anticancer, antioxidant, and have cytotoxic activity. Testing the total content of terpenoid compounds that affect the cytotoxic activity of A. compactum fruit using Box-Behnken Design with three independent variables (solvent ratio, ethanol concentration, and extraction time) has never been studied before. Thus, this study aimed to obtain the extraction optimization conditions on the total terpenoid content and cytotoxic activity using Artemia salina Leach larvae with the response surface method, namely Box-Behnken Design with Design Expert 13.0 application. Determination of the total terpenoid content of the A. compactum fruit extract was carried out based on the standard ursalic acid, and the cytotoxic activity was carried out using the Brine Shrimp Lethality Test (BSLT) method. The maximum total terpenoid obtained was 4.8970 mg UAE/g DW, and the minimum IC50 value was 38.8813 ppm. Optimal conditions for the extraction of A. compactum fruit obtained a combination of 1:8 mL/g solvent ratio, 50% ethanol concentration, and extraction time of 1 day with a desirability value of 0.772. Furthermore, the optimal extraction solution results from the Box-Behnken Design were verified and analyzed using a One-Sample T-Test. Using the Box-Behnken Design extraction optimization method, the content of terpenoid bioactive compounds with cytotoxic activity from A. compactum fruit can be optimally obtained.
The Number of Alveolar Bone Cells Exposed to Zoledronate in the Post-Tooth Extraction Socket Lubis, Septina Sabilla; Palupi, Anggraeny Putri Sekar; Komariah, Komariah; Latief, Benny Syariefsjah; Priosoeryanto, Bambang Pontjo; Suniarti, Dewi Fatma
Journal of Syiah Kuala Dentistry Society Vol 9, No 2 (2024): December 2024
Publisher : Dentistry Faculty

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/jds.v9i2.41502

Abstract

Background: Zoledronate is an intravenous bisphosphonate that effectively treats osteoporosis by inhibiting osteoclast resorption, thereby reducing the risk of fractures. However, its use in post-extraction patients may increase the risk of bisphosphonate-related osteonecrosis of the jaws (BRONJ). Objective: This study aims to analyze the effects of zoledronate on alveolar bone structure in Sprague Dawley rats, focusing on changes in osteoblast, osteocyte, and osteoclast counts. Methods: This cross-sectional study employed an observational analytical approach. Samples were categorized based on zoledronate exposure. Osteoblast, osteocyte, and osteoclast counts were measured using ImageJ software at 40x magnification. Data were analyzed using SPSS, with one-way ANOVA employed for statistical analysis. Normality and homogeneity tests were conducted to ensure data validity. Results: Zoledronate exposure resulted in a decrease in osteoblast and osteoclast counts, while osteocyte counts increased. Statistical analysis showed no significant differences between the zoledronate-exposed group and the control group. Conclusion: Zoledronate reduces osteoclasts and increases osteocytes, potentially leading to cellular apoptosis in osteoporosis patients. The risk of BRONJ can be minimized by administering zoledronate at appropriate doses and maintaining optimal oral hygiene to prevent bacterial activity.
Toxicity and Antioxidant Activities of Indonesian Rambutan (Nephelium lappaceum L.) Peel Extracts: A Comparative Analysis Across Varieties Based on Phytochemical Content Failasufa, Adzkia; Batubara, Irmanida; Priosoeryanto, Bambang Pontjo; Ilmiawati, Auliya
Jurnal Kimia Sains dan Aplikasi Vol 28, No 8 (2025): Volume 28 Issue 8 Year 2025
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.28.8.416-425

Abstract

Indonesia has long been known as a tropical country rich in various local cultivars of rambutan (Nephelium lappaceum L.), including Aceh Lebak (AL), Aceh Pelat (AP), Binjai (B), Gula Batu (GB), and Sikoneng (SK). Due to their phenolic and flavonoid compound, rambutan peel extracts have been reported to exhibit antioxidant and antiproliferative properties. Variation among cultivars suggests potential differences in bioactive compound content and biological activity. The objective of this study was to evaluate the antioxidant and toxicity profiles of five rambutan peel varieties and their correlation with total phenolic compound (TPC) and total flavonoid content (TFC). The antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, and phenolic and flavonoid contents were measured by colorimetric assays. Toxicity was assessed using the Brine Shrimp Lethality Test (BSLT). Bioautography analysis using TLC-DPPH was conducted to identify antioxidant-active compounds. In this study, all rambutan peel extracts indicated the presence of flavonoids, phenolics, saponins, steroids, alkaloids, and triterpenoids. The highest extract yield was observed in Sikoneng, also with the highest TPC and TFC values. The Binjai variety exhibited strong antioxidant activity (IC50 = 4.73 ± 0.19 mg/L) and three active antioxidant spots; however, it also exhibited toxicity (LC50 = 136.27 ± 6.58 mg/L). The correlation between total phenolic or flavonoid content and the observed biological activity was not statistically significant, indicating that additional metabolites or synergistic interactions may also contribute. These findings underscore the significant impact of biodiversity on differences in compound levels and potential biological activities among rambutan peel varieties.
Co-Authors . CHURIYAH . Darmawi Adhi Rahmat Hariyadi Aditya Primawidyawan Agus Susanto Ahmad Aulia Ahmad Aulia Andra Hendriarto Andri Hardianto Andri Lubis Andri Prasetiyo Anggraeny Putri Sekar Palupi Anggraini, Lutvi Anissa Canintika Anita Esfandiari Annisa Fitriyana Ardi Sandriya Ari Fahrial Syam Ari Fahrial Syam Aria Kekalih Asri, Lia Amelia Tresna Wulan Aulia Andi Mustika Auliya Ilmiawati Az Zahra, Shafiyyah Azhari Azhari Bambang Sunendar Purwasasmita, Bambang Sunendar Bayu Febram Bayu Febram Bayu Febram Prasetyo Bethy Suryawathy Hernowo Betty S.L. J Betty Sri Laksmi Jenie Budi Arifin Chudahman Manan Chudahman Manan Dahlia Sutanto Daldiyono Daldiyono Daldiyono Daldiyono Darmawi D Deddy Muchtadi Dede Robiatul Adawiyah Deni Noviana Denny Widaya Lukman Dewi Fatma Suniarti Dewi Ratih Agungpriyono Djarot Sasongko Hami Seno Dwi Kesuma Sari Dyah Sulistyani Rahayu Edy Djauhari Purwakusumah Eka Nurul Qomaliyah Elisabet Tangkonda Endang Prangdimurt Endang Prangdimurti Endang Sjamsudin Erniati, Erniati Esti Mumpuni Eva Harlina Evy Damayanthi Fachriyan Hasymi Pasaribu Fachriyan Hasymi Pasaribu Fachrul Razi Fadila Raisyadikara Failasufa, Adzkia Farra Sasmita Franky Oscar, Franky Fransiska R. Zakaria Fransiska Rungkat Zakaria Fransiska Rungkat Zakaria Gatot T. Mulyadi Gatot Trimulyadi Rekso Gunanati Soedjono Gunanti Gunanti . GUSTAF ADOLF WATTIMENA Hamny Sofyan Hartanti Hartanti Hartanti Hartanti, Hartanti Hasim Hasim Hatibie, Mendy Juniaty Hatta, Isnur Herwin Pisestyani Hidayat Syarief Husnawati, . I Made Kardena I Nyoman Suarsana I Nyoman Suartha I Wayan Gorda I wayan Teguh Wibawan IETJE WIENTARSIH Irmanida Batubara Iwan Harjono Utama Jimmy Pangihutan Juliana, Dara Kazuyuki Uchida Koeswinarning Sigit Komariah Komariah Kreshanti, Prasetyanugraheni Kuroki, Yutaka KUSMARDI KUSMARDI Kusumawati, Nina Tri Lanniari, Nafrina Latief, Benny Syariefsjah Latifah Darusman Lilis Nuraida Lina Noviyanti Sutardi Lisni Noraida Lubis, Septina Sabilla Lucky Riawan Lusi Epsilawati Madyastuti, Rini Mahdi Abrar Makmuri Yusuf MARIA BINTANG Maya Shofa Mieke Hemiawati Satari Mieke Hemiawati Satari Mieke Hermiawati Satari Miksusanti Miksusanti Mirnawati Soedarwanto Mirnawati Soedarwanto Mirnawati Soedarwanto Monica Septiani Muharty, Annisya Najmah Najmah Nancy Dewi Yuliana Naoaki Misawa NASRIANTI SYAM, NASRIANTI Nina Kusumawati Nur Fathonah Sadek Nurhidayat - Nurhidayat, Nurhidayat Okabayashi, Tamaki Prangdimurt, Endang Priskila Priskila Putu Angga Wiradana Putu Eka Sudaryatma Rachmi Ridho Rahmadansah Rahmadansah Rahminiwati, Min Rahyussalim Ratna Puspita Rayendra, Raendi Retno Wulansari Rifki Septawendar Riki Siswandi Rimbawan , Rini, Dian Cipta Ripta Mustafa Nugraha Risa Tiuria Riski Rostantinata Riski Rostantinata Rizal Syarief Rizal Syarief Rizki Fitria Rizki Rostantinata Ros Sumarny Rostantinata, Riski Ryoji Yamaguchi Sabri Mustafa Sadek, Nur Fathonah Safrida Safrida Sajida Sajida Samuel Leonardo Silitonga SANTOSO CORNAIN Sarifah, Norlaila Sebayang, Shalina SILMI MARIYA Slamet Budijanto Sri Anna Marliyati Sri Estuningsih Sri Kayati Widyastuti Subangkit, Mawar Sugeng Supriadi, Sugeng Sukasah, Chaula Luthfia Sunardhi Mangundjaja, Sunardhi Surachmi Setiyaningsih Surachmi Setyaninigsih Surya Pangidoan Nasution Suryani Suryani Suryani Suryani Susi Susanah Susumu Tateyama Syamsudin Abdillah Takeshi Katayama Tena Djuartina, Tena Toshisada Suzuki Tri Isyana Tungga Dewi Tri Isyani Tungga Dewi Tungga Dewi, Tri Isyani Tutik Wresdiyati Ummu Balqis Vetnizah Juniantito Wahyuni, Sri Waras Nurcholis Wasmen Manalu Wati, Vivi Septya Weko Adhiarto, Weko Wiranti, Rahayu Woro Yonathan Arderian Mantik Ziad Alaztha