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All Journal Biospecies Quagga Jurnal Bioterdidik: Wahana Ekspresi Ilmiah Bioedukasi: Jurnal Pendidikan Biologi Jurnal Biologi Universitas Andalas JINOP (Jurnal Inovasi Pembelajaran) JPS Unimus Jurnal Inovasi Pendidikan IPA Jurnal Florea Edufisika: Jurnal Pendidikan Fisika Edu Sains: Jurnal Pendidikan Sains dan Matematika Jurnal Pendidikan Biologi Padjadjaran Journal of Dentistry Unnes Science Education Journal Jurnal Pendidikan Biologi Didaktis: Jurnal Pendidikan dan Ilmu Pengetahuan Jurnal Penelitian Pendidikan IPA (JPPIPA) INKUIRI : Jurnal Pendidikan IPA BIOEDUKASI Biosfer: Jurnal Pendidikan Biologi BIOEDUSCIENCE Jurnal SOLMA Jurnal Biologi Tropis Pendas : Jurnah Ilmiah Pendidikan Dasar Diklabio: Jurnal Pendidikan dan Pembelajaran Biologi Justek : Jurnal Sains Dan Teknologi Bio Educatio : The Journal of Science and Biology Education Perspektif Ilmu Pendidikan Jurnal Cendekia : Jurnal Pendidikan Matematika Bio-Lectura Jurnal Ilmu Pendidikan (JIP) STKIP Kusuma Negara JPBIO (Jurnal Pendidikan Biologi) Bioedusiana: Jurnal Pendidikan Biologi EDUKATIF : JURNAL ILMU PENDIDIKAN Murobbi: Jurnal Ilmu Pendidikan Jurnal Pembelajaran Biologi : Kajian Biologi dan Pembelajarannya JURNAL BIOEDUCATION Atrium Pendidikan Biologi JURNAL PENDIDIKAN MIPA Biopendix: Jurnal Biologi, Pendidikan dan Terapan Jurnal Pembelajaran dan Biologi Nukleus Dedikasi: Jurnal Pengabdian Masyarakat Bio-Inoved : Jurnal Biologi-Inovasi Pendidikan Jurnal ABDINUS : Jurnal Pengabdian Nusantara UTAMAX : Journal of Ultimate Research and Trends in Education BioEksakta : Jurnal Ilmiah Biologi Unsoed Indigenous Biologi Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) Bioscientist : Jurnal Ilmiah Biologi Integrated Science Education Journal JIPB (Jurnal Inovasi Pembelajaran Biologi) Jurnal Jendela Pendidikan Journal of English Language and Education SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Bioed : Jurnal Pendidikan Biologi FORTE JOURNAL Journal of Community Engagement Research for Sustainability Indonesian Journal Of Educational Research and Review Edumatica: Jurnal Pendidikan Matematika Jurnal Ilmiah Ilmu Terapan Universitas Jambi MIMBAR INTEGRITAS Jurnal Nusantara Mengabdi Enrichment: Journal of Multidisciplinary Research and Development Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Jurnal Pengabdian Masyarakat Pinang Masak Journal of Law, Education and Business Gudang Jurnal Multidisiplin Ilmu Jurnal Esabi (Jurnal Edukasi dan Sains Biologi) Bhinneka: Jurnal Bintang Pendidikan dan Bahasa Journal Innovation In Education Symbiotic: Journal of Biological Education and Science JUPEMA Jurnal Intelek Dan Cendikiawan Nusantara BIOGENIC: Jurnal Ilmiah Biologi Jurnal Intelek Insan Cendikia Biodik: Jurnal Ilmiah Pendidikan Biologi Polygon: Jurnal Ilmu Komputer dan Ilmu Pengetahuan Alam International Journal of Computer Technology and Science Jurnal Pendidikan Progresif Asian Journal of Science Education Educational Leadership and Management Journal Jurnal Cakrawala Pendidikan dan Biologi (jucapenbi) Jurnal Ilmiah Pendidikan Citra Bakti
Jodion Siburian
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Mouse Models in Sarcopenia Research: A Literature Review Putri Julia; Nani Asyahri; Fitriya Setiani; Lili Sardona; Jodion Siburian; Afreni Hamidah; Desfaur Natalia
Jurnal Biologi Tropis Vol. 26 No. 3 (2026): Juli - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i3.12446

Abstract

Sarcopenia is defined as the progressive decline in skeletal muscle mass, strength, and function associated with the aging process. This literature review aims to analyze various mouse models used in sarcopenia research, with a primary focus on the C57BL/6 strain. A narrative literature review was conducted systematically by searching the Scopus and Google Scholar databases using the keywords “sarcopenia”, “mouse model”, “muscle atrophy”, and “C57BL/6”. A total of 12 relevant articles published between 2020 and 2024 were selected based on the inclusion criteria.The analysis results showed that muscle mass decline in mice generally begins progressively at the age of 18–24 months and becomes more significant at 23-32 months, with male mice being more susceptible than females. Natural aging, dexamethasone induction, and immobilization models were the most frequently used, consistently demonstrating type II fiber atrophy, mitochondrial dysfunction, increased ROS, and suppression of the mTORC1 pathway. Therapeutic candidates such as Delta-Like 1 Homolog (DLK1) and Ulmus macrocarpa extract showed promising effects in reducing muscle atrophy. Although mouse models provide valuable insights into the mechanisms of sarcopenia, biomechanical differences and sex-specific responses between mice and humans must be considered to enhance the translational value of the research. This review is expected to serve as a reference for researchers in selecting the appropriate mouse model for sarcopenia studies.
Eksplorasi Model Genics Terhadap Metakognitif dan Kompetensi Komunikasi Interpersonal Murid pada Pembelajaran Biologi: Studi Mixed Methods Embedded Design Renisa Abdullah; Jodion Siburian; Raissa Mataniari
Journal of Law, Education and Business Vol. 4 No. 2 (2026): Oktober 2026
Publisher : CV. Rayyan Dwi Bharata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57235/jleb.v4i2.8878

Abstract

Penelitian ini bertujuan menganalisis pengaruh model pembelajaran GENICS dibandingkan Problem Based Learning (PBL) terhadap metakognitif dan kompetensi komunikasi interpersonal murid, serta mendeskripsikan perilaku dan faktor-faktor yang memengaruhi kedua kemampuan tersebut. Penelitian menggunakan desain Mixed Methods Embedded Design dengan pendekatan kuasi eksperimen sebagai metode utama dan studi kasus sebagai metode pendukung. Data kuantitatif dianalisis menggunakan uji ANCOVA dan MANCOVA, sedangkan data kualitatif hasil observasi dianalisis menggunakan NVivo 15. Hasil penelitian menunjukkan bahwa model GENICS tidak berpengaruh signifikan terhadap metakognitif maupun kompetensi komunikasi interpersonal dibandingkan PBL. Namun, hasil observasi menunjukkan bahwa kedua model sama-sama memfasilitasi berkembangnya metakognitif dan kompetensi komunikasi interpersonal melalui aktivitas diskusi, kerja sama, presentasi, dan refleksi. Perkembangan kedua kemampuan tersebut dipengaruhi oleh faktor pendukung, seperti sintaks pembelajaran dan diskusi kelompok, serta faktor penghambat berupa keterbatasan waktu, partisipasi murid yang belum merata, ketidakhadiran murid, dan kondisi pembelajaran. Dengan demikian, model GENICS berpotensi menjadi alternatif pembelajaran untuk mendukung pengembangan metakognitif dan kompetensi komunikasi interpersonal murid.
PENERAPAN MODEL DISCOVERY LEARNING TERHADAP KEMAMPUAN BERPIKIR KRITIS SISWA DALAM PEMBELAJARAN BIOLOGI: LITERATURE REVIEW Ganda Doloksaribu, David; Ariza, Cynthia; Putri; Lestari, Farina; Siburian, Jodion; Sadikin, Ali; Mardiyanti, Lely
Pendas : Jurnal Ilmiah Pendidikan Dasar Vol. 11 No. 02 (2026): Volume 11 No. 2, Juni 2026 Release
Publisher : Program Studi Pendidikan Guru Sekolah Dasar FKIP Universitas Pasundan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23969/jp.v11i02.53441

Abstract

This study aims to analyze the effect of the Discovery Learning model on students’ critical thinking skills through a literature review method. The study was conducted by collecting and analyzing 20 scientific articles related to the implementation of Discovery Learning in various levels of education, including elementary school, junior high school, senior high school, and higher education. The data sources were obtained from national journals, proceedings, and scientific articles indexed through Google Scholar and several educational journal databases. The stages of the study included identifying research topics, searching relevant articles, selecting articles based on suitability, analyzing research findings, and drawing conclusions from the reviewed literature. The results of the review indicate that the Discovery Learning model has a positive and significant effect on improving students’ critical thinking skills. This learning model encourages students to actively participate in discovering concepts, analyzing problems, and solving problems independently. In addition, Discovery Learning also improves learning motivation, learning outcomes, student activity, and conceptual understanding. The use of supporting learning media such as multimedia, interactive CDs, smart stickers, and digital platforms also increases the effectiveness of Discovery Learning implementation. Therefore, the Discovery Learning model can be used as an alternative learning model to support the development of 21st century skills, especially critical thinking skills.
Co-Authors Abda Abda Ade Octavia Adhel Shalsabila Adinda Mutiara Ulfa Adinda Mutiara Ulfa Adriani Adriani Afreni Hamidah Agus Subagyo Agus Subagyo Agustina, Nurria Ahmad Sazali Ailsa Nadia Outhariy Aini Habi Ruhmi Ali Sadikin Ali Sadikin Alia Petra Siboro Aloysius Duran Corebima Amanda Riskina Ramadhani Amelia, Dwi Anggun Br Sihotang Anisa, Fitria Annisa Rahma Dieni Chaniago Aprizal Lukman Aprizal Lukman Aprizal Lukman Ardila, Ayudita Ariza, Cynthia Arni Ramadhani Asni Johari Aswinda Aswinda Atmanda, Aulia Ayu Febriasari Ayu Mutoharoh Ayudita Ardila Bambang Hariyadi Bambang Hariyadi Bayu Rosadi Bestia Dewi Br Munthe, Winda Br. Purba, Desi Ariani Putri Budiarti, Retni S Bunga Deli Anjani Cahaya Indah Cahaya indah Cahayu, Sri Anika Cantika Rusmaleni Cinta Serlina Damris Muhammad Dara Mutiara Aswan Dawam Suprayogi Defina, Azzira Welmi Desfaur Natalia Desfaur Natalia Desi Ariani Putri Br Purba Desi Ariani Putri Br. Purba Desy Komala Sari Dhea Febria Dian Arisandy Dian Arisandy Eka Putra Sembiring Dian Arisandy Eka Putra Sembiring Dian Paramita Dias Larasati DINI MAIDIKA Dwi Lestari Aryani Dwi Noerjoedianto Dwi Suryahartati Eka Putri Sembiring Eko Prasetyo Elka Indra Wati Elsa Rima Prahesti Elvarian Elvarian Enjelina Sinaga Erawati Sonia Eri Mangaranap Ervan Johan Wicaksana Ester Br Aritonang Ester Herwina Br Kaban Eva Khairani Astri Evid Arfan Evita Anggereini Evita Anggereini Evita ANGGREINI Febilia Asdenafika Febriasari, Ayu Fitra Wahyuni Fitri Astriawati Fitri, Islakahul Destia Fitriya Setiani Fitriya Shalehati Fulsiana Yustia Ganda Doloksaribu, David Gultom, Renny Bunga Evelyna Guspianto Guspianto Gusti Ayu Muthia Gusti Ayu Muthia Gusti Ayu Muthia Hakim, M. Arif Rahman Harlis Harlis Haryadi Haryadi Hendra Dhermawan Sitanggang Ibrohim Ihsan, Mahya Iklimalia, Iklimalia Ilham Falani Ilhami, Mohammad Ine Tentia Irawan, Nevilia Pramesti Iswara, Bintang Dwi Jastiana, Diel Aknova Jefri Marzal Jehlie Alaisa Marasigan Contreras Jeklin Hutagaol Jeri Marlina Julian Pratama Junia, Resy Juriah Juriah Kharisma Dwi Khorneliana Koiriah, Miftahul Lestari, Farina Lili Sardona Lubis, Suriati M Rusdi M Rusdi M. Erick Sanjaya M. Farhan Aditiya M. Ridwan Maheni Maheni Mardiyanti , Lely MARIA BINTANG Marina Girsang Masitah Masitah Mataniari, Raissa Mayang Dela Kesumah Meilin Meilin Meilin, Meilin Meitafia, Elda Meitafia Melly Dwi Febriani Mia Susandira Miftahul Koiriah Muda, Mhd. Abror Muzakkir Muhammad Akhir Muhammad Haris Effendi Hasibuan Muhammad Rusdi Muhammad Rusdi Muhammad Yusuf Muhammad Yusuf Mulya, Yonata Wira Murni Sapta Sari Mursalin Mursalin Mursyd, Danial Musli musli Mutmaenah, Shucy Nabila Alifa Pramani Nadia Amanda Putri Nailla Ramadani Nani Asyahri Nasha Febiola Nasution, Helmi Suryani Nasution, Purnama Nasywa Qurrota Aini Natalia D.M. Silitonga Natalia DM Silitonga Natalia Sitohang Natasya Maharani Naveny, Latifa Nayla Nabilla Nevilia Pramesti Irawan Niken Alya Salsabila Niwanda Azela Putri Nizlel Huda Novia Anggraini Nur Izzatil Arasyi Tyas Nurbudi Nur Rohman Nurdin, Fatonah Nurul Oktaviani Oktafiami, Azzahra Oktavia, Sri Wina Oktaviani, Nurul Pinta Murni Prahesti, Elsa Rima Putri Putri Julia Putri, Febriyanti Qurrota’Aini, Nasywa Raissa Mataniari Ramadhani, Arni Ratu Sampurna Ratu Rd. Halim Renisa Abdullah Renny Listiawaty Richa Amalia Ridoi Warneck Siburian Rika Lutfiana Sari Rini Rahma Dina Rini, Willia Novita Eka Rizki Ibnu Rahmad Robin Pratama Rosa Gustiara Rosita Rosita Rts Mustika Rimba Rustina, Desi Rz, Rusnelly Isrika S.F. Hayati Salsabila, Niken Alya Salsabila, Syifa Salyabila Zahrani Sanjaya, M. Erick Saparuddin Saparuddin Saparuddin Saparuddin Saparudin Saparudin Sari, Cindi Rilyan SAUDAGAR, FERDIAZ Selia Aina Septia Yuliadip Shalehati, Fitriya Simamora, Lidia Contesa Simamora, Lika Nurmala Sari Sintia Suci Sri Anika Cahayu Sri Purwaningsih Sri Rahayu Sri Susilawati Sulton Nawawi Suryaningrum Suryaningrum Sutrisno Syaiful . Syaiful Syaiful Tasya Rahmawati Tasya Sianturi Tazzania, Rivanna Tia Wulandari Titik, Titik Tohiri, Dhiya Millatika Ummi Kalsum Upik Yelianti Utomo, Pradita Eko Prasetyo Vinalia Amanda Wicjaksono, Dealvi Winda Dwi Kartika, Winda Dwi Wiwit, Wiwit Mustika Wulan Rahmadaniati Yafitriani Loi Yusuf, Ashif Irvan Zahra, Mahar Hazzillia Az