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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. E-Jurnal Medika Udayana Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Biology, Medicine, & Natural Product Chemistry Jurnal Kedokteran MNJ (Malang Neurology Journal) Jurnal Biologi Tropis Indonesian Journal of Cardiology Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Medika Malahayati Majalah Kedokteran Neurosains Jurnal Gema Ngabdi Medika Kartika : Jurnal Kedokteran dan Kesehatan Jurnal Pengabdian Masyarakat Sains Indonesia (Indonesian Journal Of Science Community Services) Jurnal Abdi Insani Sasambo Journal of Pharmacy Cermin Dunia Kedokteran JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Acta Neurologica Indonesia Lombok Medical Journal Jurnal Kesehatan Masyarakat Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Herpan Syafii Harahap
Departemen Neurologi, Fakultas Kedokteran Universitas Mataram
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Diagnosis dan Tatalaksana Guillain Barré Syndrome Grandis Cristagalli; Harahap, Herpan Syafii; Safat Wahyudi; Aulia Dwi Hendriani; Izza Mufida; Muhammad Sutan Maulana; Rike Delya Rizqina
Lombok Medical Journal Vol. 3 No. 1 (2024): Lombok Medical Journal Volume 3 Nomor 1
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i1.2886

Abstract

Guillain-Barré Syndrome or GBS is one of the emergency conditions of neurology. Currently, its incidence is relatively low and rare, with a rate of 0.81 to 1.89 of 100,000 people in a year. Guillain-Barré Syndrome or GBS, also known as acute inflammatory demyelinating polyradiculoneuropathy, is a collection of clinical symptoms caused by an acute inflammatory process that attacks the nervous system. The dominant pathogen that causes Guillain-Barré Syndrome (GBS) is Campylobacter jejuni (C. jejuni). Infection with the pathogen Campylobacter jejuni can trigger an immune and humoral autoimmune response that results in nerve dysfunction and the emergence of GBS symptoms. The clinical course of GBS can be divided into several phases, including the progressive phase, plateau phase, and recovery phase. In cases of GBS, it is possible that these factors are involved in the onset of the disease. Some risk factors associated with GBS include viral infections such as Zika virus, influenza virus, and measles-rubella virus. The diagnosis of GBS includes the main symptoms, additional symptoms, cerebrospinal fluid examination, electrophysiological tests, and the exclusion of other diagnoses. The main symptoms include progressive weakness in the extremities accompanied by or without ataxia and areflexia or hyporeflexia in the tendons. The management that can be done includes supportive therapy through the respiratory system. Another treatment option is immunotherapy, with the goal of accelerating disease recovery and reducing the severity of GBS through the immune system.
Article Review Potensi Senyawa Ginkgolide dan Bilobalide dalam Ekstrak Daun Ginkgo Biloba sebagai Terapi Penyakit Parkinson Karima, Khaula; Gina Syafinatunnajah; Haditya Novan Kasprata; Irsyadina Hasana Bharata; Jihan Alifa Rahma; Herpan Syafii Harahap
Lombok Medical Journal Vol. 2 No. 3 (2023): Lombok Medical Journal Volume 2 Nomor 3
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v2i2.3172

Abstract

Parkinson's disease is a neurological disorder that can be a major source of disability throughout the world. Changes in conditions in the body, such as α-Syn mutations can increase the risk of developing Parkinson's disease. α-Syn mutations will cause the loss of large and selective dopaminergic neurons in the substantia nigra pars compacta (SNpc) thereby triggering the early symptoms of Parkinson's disease. The high risk of side effects in the use of modern pharmacological therapy, indicates that a new breakthrough in the form of herbal-based ethnomedicine therapy for patients with Parkinson's disease is urgently needed. Ginkgo leaf, from the Ginkgo biloba plant, has long been known as a popular herbal supplement in Europe, Asia and America. The content of active compounds in ginkgo leaves was found to have the potential to provide therapeutic effects in patients with Parkinson's disease. This article will discuss the potency, mechanism of action, extraction process, and comparison of the potency of the two compounds with previous therapies. The development of the potential of ginkgo leaves is expected to reduce the increasing number of cases and provide a better quality of life in patients with Parkinson's disease.
Peningkatan Kecerdasan Memori Spasial pada Anak Melalui Permainan Tradisional Engklek Praditna, Ardi; Chivan Agustinus Siregar; Nafisya Ayu Evana; Herpan Syafii Harahap
Lombok Medical Journal Vol. 3 No. 2 (2024): Lombok Medical Journal Volume 3 Nomor 2
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Spatial intelligence, especially in a visual context, is the ability to construct, design, or arrange the structure of an object in space that includes various directions and positions. Spatial intelligence, especially spatial memory, develops throughout childhood along with the functional maturation of specific areas in the cerebral white matter tracts. Based on this, efforts to improve spatial intelligence are important to do in childhood, one of which is through the traditional game engklek. Children's spatial memory intelligence increases through the process of playing engklek. The engklek game can train the use of spatial memory through movement within spatial boundaries and cognitive mapping of the brain which represents images of the environment and objects in space. The method used in this literature review is by searching and reviewing various literature sourced from online databases such as PubMed as well, Google Scholar, and textbook.
Keamanan Kontrasepsi Hormonal sebagai Faktor Risiko Meningioma Briliansy, Briliansy; Harahap, Herpan Syafii
Lombok Medical Journal Vol. 3 No. 1 (2024): Lombok Medical Journal Volume 3 Nomor 1
Publisher : Faculty of Medicine, Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/lmj.v3i1.3661

Abstract

Meningioma, yang timbul dari meningen, merupakan tumor otak primer yang paling umum terjadi pada orang dewasa. Meskipun sebagian besar bersifat sporadis, faktor genetik, termasuk mutasi pada gen berkontribusi terhadap perkembangannya. Tinjauan ini mengeksplorasi interaksi yang kompleks antara pengaruh genetik dan lingkungan terhadap patogenesis meningioma, menekankan perlunya penilaian risiko dan konseling genetik. Selain itu, tinjauan ini juga menggali potensi hubungan antara penggunaan kontrasepsi hormonal, khususnya estrogen dan progestin, dengan risiko meningioma. Studi epidemiologi memberikan temuan yang beragam, dengan beberapa di antaranya menunjukkan peningkatan risiko yang tidak terlalu besar, terutama di antara pengguna jangka panjang. Adanya reseptor hormon pada meningioma menggarisbawahi pengaruh hormon terhadap pertumbuhan tumor. Namun, bukti-bukti yang ada belum meyakinkan, sehingga memerlukan interpretasi yang hati-hati dan menyoroti pentingnya penelitian lebih lanjut untuk memperjelas hubungan ini. Berdasarkan bukti-bukti yang ada, makalah ini merekomendasikan penilaian individual terhadap risiko dan manfaat penggunaan kontrasepsi hormonal, terutama bagi perempuan dengan riwayat meningioma atau faktor risiko lainnya. Penelitian yang sedang berlangsung sangat penting untuk pengambilan keputusan yang tepat dalam kesehatan reproduksi.
UPAYA INTERVENSI FISIK MELALUI SOSIALISASI SENAM OTAK (BRAIN GYM) SEBAGAI UPAYA MENGHAMBAT PROGRESIFITAS DAN MENURUNKAN ANGKA KEJADIAN DEMENSIA Rivarti, Arina Windri; Saputri, Legis Ocktaviana; Harahap, Herpan Syafii; Nurhidayati, Nurhidayati; Suryani, Dini; Stephen, Mishael Enoch; Prawiro, Aurellia Wongso; Wulandari, Inayah; muttaqin, Syihabul; Ristia, Ovia Intan; Azizaturrahmah, Gina Aulia; Balqis, Ananda amirah
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1724

Abstract

The high incidence of dementia not only poses health problems but also leads to significant social impacts and economic losses. While no potential therapy has been found to cure this disease, early diagnosis and prevention are important alternatives to prevent dementia. Brain gym is one of the physical activities known to enhance and maintain cognitive function. Various studies on brain gym have shown positive effects on the cognitive function of the elderly. This activity aims to provide socialization of Brain Gym to the community in Maringkik Island and is expected to have an impact on reducing the progression of cognitive impairment and dementia. This community service activity is divided into three stages, consisting of health education, health and cognitive function assessment, and socialization of brain gym movements to the community. This activity was enthusiastically attended by 50 participants from late adulthood to elderly. The activity went well until the end. Health education regarding brain gym techniques and benefits successfully introduced 9 types of brain gym movements and their benefits, which were well received and understood by the community. After the education session, the community successfully performed the brain gym movements introduced by the service team together. The socialization of brain gym to the community in Maringkik was carried out well with high enthusiasm from the community.
UPAYA MENURUNKAN PREVALENSI DEMENSIA MEALUI EDUKASI KESEHATAN TERKAIT FAKTOR RESIKO DEMENSIA DAN DETEKSI DINI GANGGUAN KOGNITIF PADA POPULASI LANSIA DI MASYARAKAT PESISIR LOMBOK Saputri, Legis Ocktaviana; Rivarti, Arina Windri; Harahap, Herpan Syafii; Nurhidayati, Nurhidayati; Suryani, Dini; Stephen, Mishael Enoch; Prawiro, Aurellia Wongso; Wulandari, Inayah; muttaqin, Syihabul; Ristia, Ovia Intan; Azizaturrahmah, Gina Aulia; Balqis, Ananda Amirah
Jurnal Abdi Insani Vol 11 No 3 (2024): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v11i3.1743

Abstract

Dementia is a progressive disease that affects memory and other cognitive functions. Coastal communities have a higher incidence of certain diseases compared to other areas. Degenerative diseases such as coronary heart disease, stroke, hypertension, diabetes mellitus, and dementia have an incidence rate of two to eight percent higher in coastal areas. This community engagement aims to provide health education related to the signs and symptoms as well as prevention efforts for degenerative diseases and cognitive function disorders. Health screenings are also conducted in an effort to detect cases of degenerative diseases and cognitive function disorders early. The community service activities are carried out in three coastal areas of Lombok Island. Participants enthusiastically attend health education and health screening. The results of cognitive function disorder screening show that 50.7% of the 225 participants experience cognitive function disorders. The community service activities are conducted according to plan.
The Mechanisms of Instrumental Music Playing in Preserving Cognitive Function in Adulthood Almuthiiah, Khadijah; Bayanaka, Aldhiya Azmy; Dewi, Artu Alycia Laksmi; Andiyani, Dinda Zahra Putri; Alkautsar, Mohammad Saddam; Harahap, Herpan Syafii; Briliansy, Briliansy
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.10833

Abstract

Adulthood is divided into three stages: young adulthood, middle adulthood, and older adulthood. Middle adulthood (40-65 years) is the phase where the balance between growth and neurocognitive development begins. In this phase, prevention of cognitive decline is necessary by strengthening cognitive reserves through brain stimulation through musical activities. This study used a literature review method. In this article, we conducted a search using electronic databases such as PubMed, Google Scholar, ScienceDirect, ResearchGate, and the National Institute of Health (NIH). The review found that playing music can increase dopamine in the reward system and inhibit the hypothalamic-pituitary-adrenal (HPA) axis, which can improve motivation, attention, memory, and learning processes, thus strengthening cognitive function. Findings from Balinese gamelan and flute players indicate increased alpha and beta brainwave activity, which stimulate executive function, memory, and motivation. Therefore, playing traditional Indonesian music has the potential to improve cognitive abilities as a form of prevention of neurodegenerative disorders in adulthood. It was recommended that playing music in middle adulthood will improve cognitive function by playing traditional music.
Co-Authors Abdurrachim Abdurrachim Achmad Mujahidin Irham Adre Mayza Afif, Zamroni Aisya Nur Abida Aisya Yafis Iqlima Alkautsar, Mohammad Saddam Almuthiiah, Khadijah Amalia, Emmy Amalia, Emmy - Amaliya, Annisa Risqi Amanda Halimi Amin, Hasan Anak Agung Ayu Niti Wedayani Andhera, Athalita Andi Alfian Zainuddin Andi Alfian Zainuddin Andi Kurnia Bintang, Andi Kurnia andi, Silmi chairan Andina Nabilah Mario Andiyani, Dinda Zahra Putri Anggoro, Joko Annafi, Muhammad Ibnu Anthony, Lalu Muhammad Anugrah, M. Fardi Ardiana Ekawanti Ario Danianto Asriningrum Asriningrum Asriningrum, Asriningrum Aulia Dwi Hendriani Ayu Susilawati, Ayu Azizaturrahmah, Gina Aulia Azmy Mujahid, Sabila Izzatina Badrul Munir Baiq Dewi Sartika Baiq Hilya Kholida Baiq Hilya Kholida Baiq Kania Kartika Yaksa Balqis, Ananda Amirah Bayanaka, Aldhiya Azmy Belynda Rahmalia Sanceska Wahyudi Briliansy Briliansy Briliansy, Briliansy Cahyadi, Anabel Cahyadi, Anabel Catarina Budyono, Catarina Catur Ari Setianto, Catur Ari Chivan Agustinus Siregar Christabella Natalia Wijaya Claudya, Astrid Danesh Hadyljinan Utomo Dara Asyfiya Iyoega Darmaningrat, Cokorda Istri Agung Asvini Deasy Irawati Decky Aditya Zulkarnaen Devi Chandra Kirana Dewi Suryani Dewi, Artu Alycia Laksmi Diayanti Tenti Lestari Didit Yudhanto Dimas Zul Fariqhan Dini Suryani, Dini Dion Setiawan Dwi Atri, Ausi Mutiara Eko Arisetijono Emmy Amalia Enny Ratna Indriyani Evelin, Shierly Kencana Eviana Norahmawati Fachry Prasetyo Hutomo Faizah, Lillah Fatarosdiana Fatarosdiana Fatarosdiana, Fatarosdiana Fitriantoro, Santo Gea, Endah Irnanda Ulfa ghalvan sahidu Gina Syafinatunnajah Gina Zahro Ambarah Grandis Cristagalli Habib, Phillip Haditya Novan Kasprata Hamsu Kadriyan Haq, Abiyyu Didar Hasina, Raisya Hendra Susana Putra Hendra Susana Putra Hifdzil Hilam, Muhammad I Dewa Bagus Ketut Widya Pramana I Gede Yasa Asmara I Gusti Ayu Trisna Aryani I Made Brama Atmaja Ilsa Hunaifi Ilsa Hunaifi Ilsa Hunaifi, Ilsa Indah Retnowati Indah Retnowati Indah Retnowati Indah Sapta Wardani Indradayana, Yanna Indrayana, Yanna Indrayana, Yanna Indrayana, Yanna Indrayana, Yanna Indriyana, Yanna Irsyadina Hasana Bharata Ismaya, Ferium Trah Ismiana, Baiq Holisatul Iyoega, Dara Asyfiya Izza Mufida Jacob, Lusye Diana Jihan Alifa Rahma Joko Anggoro Jumraini Tammasse Kasprata, Haditya Novan Khaula Karima Laksmana, Ngakan Putu Proudy Landapa, Raditya Rachman Lasmi, Anjely Doni Lestari, Diayanti Tenti Lestari, Rizka Vidya Linggabudi, I Gusti Bagus Widiamtara Loeki Enggar Fitri Luh Made Ita Purwani Maharani, Amelia Wahyu Maharani, Nyoman Ayu Anindya Mahardika, Fransisca Ika Maida sania salsabila Maliga, Helnida Anggun Mega Adwiatin Miraditi, Ni Komang Mochammad Dalhar Muhammad Akbar Muhammad Akbar Muhammad Azrul Uzmi Muhammad Ghalvan Sahidu Muhammad Ghalvan Sahidu Muhammad Sutan Maulana Muhammad Zaariq Prasetyo Mukhlisatunnafsi, Latifah Muliyana, Hifdzil Haq Munirah, Ira Muttaqin, Syihabul Nafisya Ayu Evana Neila Raisa Ni Nyoman Ayu Susilawati Ni Nyoman Ayu, Susilawati Ni Wayan Sekar Ratih Nikmahtustsani, Mulika Ade Fitria Novita, Adela Novrita Padauleng Nur Syamsu, M.Diaz Nurarafah Andika Putri Nurfadia, Muhammad Fabian Nurhayati, Putri Nurhayati, Rohmatul Hajiriah Nurhayati, Rohmatul Hajiriah Nurhidayati Nurhidayati Nurhidayati Nurhidayati Nurhidayati Nurhidayati Ocktaviana Saputri, Legis Padauleng, Novrita Padauleng, Novrita Padauleng, Novrita Paniatul Hiwala Pintaningrum, Yusra Praditna, Ardi Prafica, Adisti Prasetya, Rangga Cahya Pratiwi, Baiq Bunga Citra Prawiro, Aurellia Wongso Pujiarohman Pujiarohman Pujiarohman, Pujiarohman Putra, Hendra Susana Putri Nurhayati Putri, Setyawati Asih Putri, Siti Noururrifqiyati Juna Qisthinadia Hazhiyah Setiadi Rahma, Jaini Raisa, Neila Rifky Maulana Ackbar Rike Delya Rizqina Rina Lestari Rina Lestari Ristia, Ovia Intan Rivarti, Arina Windri Rizki, Mohammad Rizki, Mohammad Rohadi Muhammad Rosyidi Rosmalasari Rosmalasari Rusdi, Yudika Ilhami Safat Wahyudi Safat Wahyudi Safat Wahyudi Sahidu, Muhammad Ghalvan Sahly, Aliza Raudatin Sari, Putu Suwita Satriawan, Wira Semadi, I Kadek Setiadi, Qisthinadia Hazhiyah Setiadi, Qisthinadia Hazhiyah Setyawati Asih Putri Shafa C, Cloresta Silmina Alifiya Sri Budhi Rianawati Sri Budhi Rianawati, Sri Budhi Sri Susilawatin Stephanie Elizabeth Gunawan Stephanie Elizabeth Gunawan Stephanie Elizabeth Gunawan Stephen, Mishael Enoch Sulistyaningrum, Dwi Suryantarini, Ni Wayan Puspa Wijaya Susilawati, N Nyoman Ayu Susilawati, Ni Nyoman Ayu Syifa, R.R Ditya Mutiara Tammasse , Jumraini Tammasse, Jumraini Tinny Endang Endang H Ulfa Gea, Indah Ernanda Vinni Dianggita Wa Ode Nur Intan Octina Wahyudi, Safat Wardi, Baiq Prita Riantiani Wedayani, AA Ayu Niti Wiracakra, I Gusti Lanang Krisna Wulandari, Inayah Yanna Indrayana Yusra Pintaningrum Zamroni Afif Zubaidi, Fitriannisa Faradina