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Analisis Interaksi Obat pada Pasien Gagal Ginjal Kronis yang Menjalani Hemodialisis di RSUD Dr. Pirngadi Kota Medan Situmorang, Lusi Grasia; Rawitri, Kiki; Dalimunthe, Gabena Indrayani; Nasution, Haris Munandar
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 2 No. 1 (2024): Bulan Juli 2024 Faskes : Jurnal Farmasi, Kesehatan, dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v2i1.3172

Abstract

Latar Belakang: Gagal ginjal kronis menjadi salah satu penyebab kematian di dunia dalam berbagai kelompok umur. Kompleksitas pengobatan dengan dengan penyakit gagal ginjal kronis dapat meningkatkan kejadian Drug Related Problems (DRPs). DRPs merupakan suatu kejadian yang berkaitan dengan terapi obat secara aktul atau potensial yang berdampak pada hasil kesehatan seseorang. Tujuan: Penelitian ini bertujuan untuk mengetahui kejadian Drug Related Problems (DRPs) kategori interaksi obat pada pasien gagal ginjal kronis yang menjalani hemodialisis di RSUD Dr. Pirngadi Kota Medan. Metode: Penelitian ini merupakan penelitian observasional dengan desain cross sectional, populasi pada penelitian adalah pasien gagal ginjal kronis yang menjalani hemodialisis, teknik pengambilan sampel menggunakan teknik simple random sampling. Pengambilan data secara retrospektif dan analisis data menggunakan program SPSS. Hasil: Hasil penelitian menunjukkan terdapat kejadian DRPs kategori terjadi interaksi obat 25 pasien (34,7%) dan tidak terjadi interaksi obat 47 pasien (65,3%). Interaksi obat yang terjadi dengan tingkat keparahan sebanyak 52 kasus, keparahan mayor 4 kasus (7,68%), tingkat keparahan moderat 46 kasus (88,50%) dan tingkat keparahan minor sebanyak 2 kasus (3,84%). Kesimpulan: Berdasarkan hasil penelitian disimpulkan bahwa terdapat kejadian DRPs kategori interaksi obat sebanyak 34,7% pada pasien gagal ginjal kronis yang menjalani hemodialisis di RSUD Dr. Pirngadi Kota Medan.
Characterization and Phytochemical Screening of Rambai Leaf Extract (Baccaurea motleyana Mull.Arg) from Peureulak, Aceh. M. Alfaruqi; Rani, Zulmai; Indrayani, Gabena; Nasution, Haris Munandar
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 3 No. 01 (2025): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v3i01.91

Abstract

The rambai plant (Baccaurea motleyana Mull.Arg) contains flavonoid compounds scattered in various parts of the plant such as roots, stems, bark, twigs, leaves, fruit, flowers and seeds. Rambai leaves have various properties that have been empirically proven to cure various diseases, including wound medicine, smallpox medicine, and flu powder. The aim of this research is to find out whether rambai leaf extract contains phytochemicals and to determine the characteristics of rambai leaf extract. Phytochemical screening of rambai leaf extract (Baccaurea motleyana Mull.Arg), including examination of flavonoids, tannins, saponins, steroids/triterpenoids, alkaloids and glycosides. Phytochemical screening was carried out on simplicia powder and simplicia extract and characterization of simplicia was carried out. Testing the water content of rambai leaves was 8%, the water soluble essence content was 33.22%, the ethanol soluble essence content was 13.163% and the total ash content was 5.1% and the acid insoluble ash content was 0.3%. Rambai leaf extract positively contains alkaloids, flavonoids, saponins, tannins, steroids/triterpenoids, and glycosides.
Formulasi,dan Karakteristik Mutu Fisik serta Evaluasi Nilai Sun Protection Factor Sabun Transparan Ekstrak Daun Sirih Merah Yuniarti, Rafita; Nasution, Haris Munandar; Dachban, Syarifa Mayly B.; Putri, Nadya Iwani; Luthfianida, Arifna; Wahdaniati , Tri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.705

Abstract

The sun emits ultraviolet radiation and can produce free radicals. If these free radicals continue to come into contact with the skin excessively, they can damage cells and eventually cause cancer. Sun Protection Factor (SPF) is a substance that protects the skin from ultraviolet rays. The capacity of a product to shield the skin is indicated by its SPF rating. Soap is a type of formulation that individuals frequently utilize. Red betel leaf extract can protect the skin from the harmful effects of free radicals and is expected to increase the soap's ability to protect the skin from exposure to sunlight and maintain skin health. The methods include making transparent soap, testing physical quality, and determining the sun protection coefficient at various red betel leaf ethanol extract concentrations. The result is a transparent black-green soap with a pH of 9, a foam height of 57-65 mm, and a water content of <15%. At a concentration of ethanol extract of 0%, the SPF value is 3, and the SPF values are 7.5 (10%), 12.28 (30 and 50%), 18.2 (70%), and 25 (90%). From this information, it can be inferred that clear soap created with red betel leaf extract possesses excellent physical attributes and effectively protects against sun exposure.
Perbedaan Media Fermentasi Terhadap Produksi Protein Sel Tunggal (PST) Menggunakan Kultur Saccharomyces cerevisiae Rahayu, Yayuk Putri; Nasution , Haris Munandar; Prasetyo , Healthy Aldriany
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.846

Abstract

Utilization of pineapple peel waste and tofu liquid waste can reduce environmental impacts and is an alternative fermentation medium containing cheap and easily obtained carbohydrate sources and has the potential for the growth of Saccharomyces cerevisiae. Single Cell Protein (SCP) is a protein derived from microbes such as yeast. The purpose of this study was to determine the differences between pineapple peel waste and tofu liquid waste with the addition of different nutrients to SCP production using S. cervisiae. The research method was experimental. The independent variables were fermentation medium MK1 (pineapple peel waste; KH2PO4; sugar); MK2 (pineapple peel waste; KH2PO4; (NH4)2SO4; sugar), MT1 (tofu liquid waste; KH2PO4; sugar); and MT2 (tofu liquid waste; KH2PO4; (NH4)2SO4; sugar). The fermentation period was 0, 2, 4, and 6 days. The dependent variables were protein content, cell dry weight, glucose content, pH and temperature. The results of the SCP production research obtained the highest percentage increase in protein content in MT2 media (tofu liquid waste; KH2PO4; (NH4)2SO4; sugar) was 33.33% (day-2, increase in dry cell weight 84.90%), followed by MK2 media (pineapple peel waste; KH2PO4; (NH4)2SO4; sugar) was 13.15% (day-4, increase in dry cell weight 2.77%). The conclusion is that from both pineapple peel waste and tofu liquid waste substrates, the best PST production was obtained with the highest protein content in MT2 (tofu liquid waste media with the addition of KH2PO4; (NH4)2SO4; and sugar).
Formulasi dan Evaluasi Sediaan Permen Marshmalow Sari Buah Anggur Merah (Vitis vinifera L.) Nuratika, Eli; Dalimunthe , Gabena Indrayani; Lubis , Minda Sari; Yuniarti, Rafita
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.860

Abstract

Candy serves as a high-calorie source often consumed during activities such as working, exercising, and studying. Typically, the most common candies available in the market are soft candies with a chewy texture. When made with real fruit juice, these candies can provide additional nutrients, minerals, and vitamins to the body. This study aimed to formulate marshmallow candy using red grape juice (Vitis vinifera L.) as the main ingredient, with variations of sucrose and honey, to create a product with appealing taste, texture, and nutritional value suitable for both children and adults. The study also evaluated the physical quality of the formulated marshmallow candy. Methods: This experimental research utilized the open pan method to produce marshmallow candy. The evaluation included organoleptic tests (shape, color, aroma, taste, texture), pH testing, weight uniformity analysis, moisture content measurement, ash content determination, and hedonic testing involving 15-21 panelists. Results: All formulations (F1, F2, F3) met physicochemical quality standards, with a pH of 5, moisture content of 6.5-8.1%, ash content of 1.3-1.8%, and weight variation coefficients of 2.55-2.73%. Based on hedonic testing, formulation F2 (5 g sucrose + 44 g honey) was the most preferred, receiving the highest scores for taste, shape, and texture. Conclusion: Red grape juice was successfully formulated into marshmallow candy that meets standard physicochemical quality requirements. The combination of sucrose and honey significantly influenced product characteristics, with F2 being the optimal formulation based on consumer preference. This study contributes to the development of functional food products using natural, nutrient-rich ingredients.
Pengaruh Metode Ekstraksi Daun Jarak Cina (Jatropha multifida L.) Secara Maserasi dan Microwave-Assisted Extraction (MAE) Terhadap Aktivitas Antijamur Pada Candida albicans Aryunda, Divia; Nasution, Muhammad Amin; Nasution, Haris Munandar; Pulungan , Ainil Fithri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.868

Abstract

Introduction: Indonesia possesses high biodiversity, including the Jatropha multifida L. plant, which contains secondary metabolites with potential antimicrobial properties. Traditionally, the leaves of Jatropha multifida have been used as herbal medicine, particularly for inhibiting the growth of microorganisms. Objective: This study aims to determine the total flavonoid content in the ethanol extract of Jatropha multifida leaves and to compare the effectiveness of two extraction methods, maceration and Microwave-Assisted Extraction (MAE), in inhibiting the growth of Candida albicans. Methods: The research stages included the characterization of the powdered simplicia, extraction of Jatropha multifida leaves using 96% ethanol by maceration and MAE methods, and phytochemical screening. The total flavonoid content was determined using UV-Vis spectrophotometry at a wavelength of 431 nm. Antifungal activity against Candida albicans was tested for each extract at specific concentrations. Results: The ethanol extract obtained through maceration showed a total flavonoid content of 34.7089 ± 0.1206 mg QE/g, while the MAE method yielded 32.1923 ± 0.1113 mg QE/g. The highest antifungal activity was observed in the MAE extract at a 75% concentration, producing an inhibition zone of 24.7 mm. The maceration extract at the same concentration produced an inhibition zone of 23.7 mm. As a positive control, 2% ketoconazole resulted in an inhibition zone of 31.4 mm. Conclusion: Although the maceration method produced a higher total flavonoid content, the extract obtained through the MAE method demonstrated more potent antifungal activity against Candida albicans at the same concentration.
Formulasi dan Uji Aktivitas Antibakteri Sediaan Sabun Cair Ekstrak Etanol Daun Kopi Arabika (Coffea arabica L.) Terhadap Bakteri Staphylococcus aureus Amaliana, Amaliana; Nasution, Haris Munandar; Lubis, Minda Sari; Rahayu, Yayuk Putri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.872

Abstract

Coffee leaves (Coffea arabica L.) are a part of the coffee plant that is not widely used. Coffee leaves contain flavonoids, alkaloids, saponins, caffeine and polyphenols. Coffee leaves are a natural ingredient that has antibacterial and antioxidant activity, so they need to be used. develop it into pharmaceutical preparations to increase ease of use, one of which is liquid soap preparations The aim of this research was to determine the secondary metabolite content of simplicia powder and ethanol extract of coffee leaves, formulate ethanol extract of coffee leaves into liquid soap, determine the physical quality of the preparation and test the activity against Staphylococcus aureus bacteria. The method used in this research is to make a liquid soap formulation from Arabica coffee leaves and test its effectiveness as an antibacterial against Staphylococcus aureus bacteria. This research was carried out experimentally with the independent variable being the concentration of Arabica coffee leaf ethanol extract: F1 contains 2.5 grams of active substance, F2 contains 5.0 grams of active substance, F3 contains 7.5 grams of active substance, dependent variable: leaf simplicia phytochemical screening test Arabica coffee, antibacterial activity test against Staphylococcus aureus bacteria. Quality of liquid soap preparations from ethanol extract of Arabica coffee leaves using stability tests (pH of the preparation, homogeneity, viscosity and height of foam) and antibacterial tests using the agar diffusion method (well method). The research results show that simplicia powder and ethanol extract of coffee leaves contain alkaloid, flavonoid, tannin and saponin chemical compounds. The organoleptic test results of liquid soap have a distinctive smell, a combination of coffee and rose leaves, are blackish brown in color, and are in the form of a thick liquid. The stability test results of all formulas are stable. The pH test ranges from 9.05 to 9.43. Test foam height 35- 40 mm. The viscosity test results ranged from 735.0-894.8 cpoise, antibacterial activity had an k- (Blanko) concentration inhibition zone of  13,6 mm FI concentration liquid soap obtained a result of 15.7 mm, FII concentration liquid soap obtained a result of 18.4 mm, FIII concentration liquid soap obtained a result of 18.75 mm compared to the control positive obtained a result of 18.8 mm.
Konsentrasi Hambat Minimum dan Konsentrasi Bunuh Minimum Ekstrak dan Nanopartikel Ekstrak Etanol Daun Kubis (Brassica oleracea L.) Terhadap Malassezia furfur Rafika, Intan Maya; Rahayu , Yayuk Putri; Nasution , Haris Munandar; Miswanda, Dikki
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.874

Abstract

Background: Dandruff is a condition characterized by excessive shedding of dead skin cells on the scalp, often accompanied by itching and inflammation. The causes of dandruff can be related to excessive secretion of sweat glands or the presence of microorganisms on the scalp that produce specific metabolites that trigger dandruff formation. The organism believed to be the leading cause of dandruff is Malassezia furfur. Treatment for dandruff can be done through various methods, one of which is using natural extracts, such as ethanol cabbage extract, known for its antifungal properties. In this study, the ethanol cabbage extract will be synthesized into nanoparticle form to enhance its effectiveness. Objective: The objective of this study is to create nanoparticles from ethanol cabbage extract and to compare the antifungal activity of the cabbage extract and the nanoparticle extract of cabbage against Malassezia furfur, focusing on the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC). Method: This study was conducted experimentally, and two variables were tested. The independent variables included the concentration of cabbage extract (6.25%, 12.5%, 25%, and 50%) and nanoparticle cabbage extract (0.625%, 1.25%, 2.5%, and 5%). The dependent variables were the antifungal activity measured by MIC and MFC tests against Malassezia furfur. Nanoparticles were synthesized using the top-down method with high-speed homogenization (HSH) technique. The particle size characterization was performed using a Particle Size Analyzer (PSA). Results: Particle size characterization showed that the particle size of cabbage extract was 2203.45 nm, while the nanoparticle size after synthesis was 408.33 nm. Based on the MIC and MFC tests, it was found that the nanoparticle ethanol cabbage extract at a concentration of 1.25% was more effective than the ethanol cabbage extract at 12.5%. Additionally, the MFC value of the nanoparticle ethanol cabbage extract at a concentration of 5% was more effective than that of the ethanol cabbage extract at 50%. Both preparations demonstrated good sensitivity against Malassezia furfur. Conclusion: Nanoparticle ethanol cabbage extract showed better antifungal activity than the ethanol cabbage extract at higher concentrations. These results indicate that using nanoparticles can reduce the required dosage to achieve optimal effectiveness, thus improving the efficiency of the drug in dandruff treatment.
Konsentrasi Hambat Minimum dan Konsentrasi Bunuh Minimum Ekstrak Dan Nanopartikel Ekstrak Daun Pometia pinnata Terhadap Staphyloccocus aureus dan Escherichia coli Sony , Suyefri; Rahayu, Yayuk Putri; Nasution , Haris Munandar; Rani, Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.885

Abstract

Background: Infectious diseases caused by bacteria such as Escherichia coli and Staphylococcus aureus have become a global health issue. Matoa leaves (Pometia pinnata) are known to contain antibacterial compounds that hold potential as alternative treatments. Objective: This study aimed to produce nanoparticles from the ethanol extract of matoa leaves and compare the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values of both the extract and its nanoparticles against Escherichia coli and Staphylococcus aureus. Methods: This experimental research used different concentrations of matoa leaf ethanol extract (6.25%, 12.5%, 25%, 50%) and nanoparticle extract (0.625%, 1.25%, 2.5%, 5%). Nanoparticle characterization was performed using a Particle Size Analyzer (PSA). Results: The nanoparticle characterization showed a size of 528.95 nm. The MIC value of the matoa leaf extract against Escherichia coli and Staphylococcus aureus was 12.5%, while for the nanoparticles, it was 1.25%. The MBC value of the matoa leaf extract was 50%, and for the nanoparticles, it was 5%. The highest antibacterial activity of the ethanol extract was 18.3 mm and 18.4 mm, while for the nanoparticles, it was 18.5 mm and 19.0 mm. Conclusion: The nanoparticle extract of matoa leaves was more effective in inhibiting and killing bacteria compared to the regular extract, with a lower dose (1:10), showing its potential as an efficient antibacterial alternative.
Formulasi, Evaluasi dan Penentuan Nilai SPF Serta Uji Kelembaban Perona Pipi Stik Ekstrak Etanol Bawang Dayak (Eleutherine bulbosa (Mill.) Urb Hutagalung , Septi Ratna Cempaka; Yuniarti , Rafita; Dalimunthe , Gabena Indrayani; Lubis , Minda Sari
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.886

Abstract

Background: Blush is traditionally used to add color to cheeks, but UV exposure poses significant skin damage risks. Dayak onion (Eleutherine palmifolia), containing anthocyanins as natural pigments and photoprotective compounds, shows potential as a multifunctional blush ingredient. Objectives: The aim of this study is to determine whether Bawang Dayak can be formulated as a natural colorant for blushers, whether Bawang Dayak extract possesses sun protection properties, and whether the ethanol extract of Bawang Dayak blusher has sun protection and skin moisturizing abilities. Methods: An experimental study employing quantitative and qualitative approaches was conducted. The research stages included material characterization, phytochemical screening, SPF testing of extract and formulations, physical quality evaluation (homogeneity, stability, adhesiveness), and in vivo skin hydration testing. Ethanolic Dayak onion extract samples were prepared at varying concentrations (100-1000 ppm). Results: The ethanolic extract was successfully formulated into stick blush meeting standard physical quality criteria. The extract demonstrated ultra SPF ratings (1000 ppm: SPF 32; 700 ppm: SPF 25; 500 ppm: SPF 21) to minimal protection (100 ppm: SPF 4). The 1000 ppm blush formulation showed ultra SPF 29, while the 700 ppm formula (F2) exhibited the highest skin moisturizing capacity. Conclusion: Dayak onion shows promise as both a natural colorant and active sunscreen agent in blush formulations. The developed product meets physical quality standards while offering dual functionality as a color cosmetic with UV protection.
Co-Authors Adelia Ramadani Adjelie, Tiara Adyani Maulinda Ahmad Rasyid Ridho Alaina, Nadila Alfi Wahyudi Nasution Amaliana, Amaliana Ananda , Nadia Andjelie, Tiara Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Apmarja, Sarah Utami Aris Munandar Aryunda, Divia Asep Trizaldi Asmarani, Asmarani Aulia Fitri, Aulia Aulia Sari Auza , Maharani Ayu , Tri Indah Pagar Azhar, Gustika Barutu, Liza Anisa Shevia Basaniah Basaniah BJ Sutrisna Cici Andriani Cindy Priscilia Cindy Widya Rosa Br Simarmata Cut Dian Mala Luthfia Cut Erika Maulydya D Elysa Putri Mambang D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang Daeng Elysa Putri Mambang Daulay , Anny Sartika Delvi Amira Hutagaol Dikki Miswanda Dina Agustia Parlin Dina Suciati Saragih Dinda Sari Utami Dini Rahmadani Ellyza, Chella Emmy Wiriandini Ercha Minanda Farida Yani Fathur Rahman Fatimah, Cut Fatma Dwi Jati fatur Rahman, fatur Febiyani, Rica Fithri Pulungan, Ainil Fitri Mulyani, Fitri Fitri, Nurul Fitri, Raissa Friyani, Lilah Gabena Indrayani Dalimunthe Gultom, Syarifah Elena Hafizha, Putri Hasanah, Qori Hasibuan , Nabila Hasim Hasibuan, Supia Indah Hastri Kholifah Hutagalung , Septi Ratna Cempaka Hutagalung, Riris Br Hutagaol, Delvi Amira Huzeila Nisa Siregar Ihsan Fadhilah Ika Yeni Siahaan Ilmi Widya Sari Imelda Natasia Br S Meliala Indah Nasution Indah Triutami Harahap Indrayani, Gabena Junia Fitri Hayani Khofifah , Nur Kiki Rawitri Krisna Juniharta Napitupulu Leni Safriani Lestari, Sri Indah Linda, Rosa Lubis, Minda Sari Lubis, Nadya Frestika Luthfianida, Arifna M Pandapotan Nasution M Pandapotan Nasution M Pandapotan Nasution M. Alfaruqi M. Pandapotan Nasution M. Pandapotan Nasution M. Pandapotan Nasution M. Pandapotan Nasution Mambang , D.Elysa Putri Mambang, D. Elsya Putri Mambang, Elysa Putri Maya Syafira Meutia, Cut Miftahul Jannah Minda Sar Lubis Mohd. Bilal Muhammad Amin Nasution Muhammad Amin Nasution Muhammad Ari Mukhtizar Muhammad Hizbullah Muhammad Pandapotan Nasution Muhammad Wahyu Ikhsan Muhammad Wahyu Ikhsan Munaziatul Jannah Munthe, Herlina Nasution , Muhammad Amin Nasution, Kartika Zsaskia Nasution, M. Pandapotan Nasution, Nur Sahadah Natasya, Siti Adinda Nazirah, Nazirah Nazuhra, Oca Nelsa Fahira Ningtias, Anggitha Niswa, Khairun Nofa Lismandaria Novika Utami Nur Hanifah Nuraida Nuraida Nuratika, Eli Nurliansyah, Nurliansyah Nurul Hasanah Ovalina Sylvia Br. Ginting Pertiwi, Rahma Prasetyo , Healthy Aldriany Purba , Intan Sabila Putri Puteri, Cut Intan Annisa Putri , Adilla Putri Intan Sari Putri Khairani Putri Mambang, D. Elysa Putri Rahayu, Yayuk Putri, Nadya Iwani Rafika, Intan Maya Rafita Yuniari Rafita Yuniart Rafita Yuniarti Rafliza , Rista Rahayu , Yayuk Putri Rahmadani , Adevika Rapita Yuniarti Rati , Yuliandini Rati Satri Situmorang Rawitri, Kiki Ridho, Ahmad Rasyid Ridwanto Ridwanto Ridwanto Ridwanto Ridwanto Rina Azhari Ritonga , Septi Ani Riza Syafira RR. Ella Evrita Hestiandari Rukmana, Siti Sabila , Anisa Safira , Liyuza Safitri , Nurhaliza sahrianti, Hikmah Sari, Syilvi Rinda Sarmadansyah Sarmadansyah Sartika Daulay, Anny Sasnita, Merida Selfia Lestary Sepriani, Ananda Sinaga, Novita Yulianti Siregar , Anisah Siti Aisyah Jamil Situmorang, Lusi Grasia Situmorang, Rati Satri Sony , Suyefri Sri Harti Sri Natalia Saragih Sri Ria Ranti Sri Wahyuni Sri Wahyuni Sri Wahyuni Sulwiyatul K Sani Supiyani, Supiyani Syafira, Nona Syalsabila Putri Syara, Nurdiani Syarifah Elena Gultom Tawir Rina Rezeki Tri Damaiyanti Ummi Khairani Rambe Wahdaniati , Tri Widya Sari Widya Sari Widya, Rizka Yanti, Rahma Yayuk Putri Rahayu Yayuk Putri Rahayu Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Apriani Br.Lubis Yuniarti , Rafita Yuniarti, Rafita Zannah , Muhamad Zikra Maqfirah Ziza Putri Aisyia Fauzi Zulmai Rani