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All Journal HAYATI Journal of Biosciences Jurnal Ilmu Pertanian Indonesia Jurnal Teknologi Dan Industri Pangan Vegetalika VALENSI Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences JURNAL KIMIA SAINS DAN APLIKASI AL KAUNIYAH Buletin Penelitian Tanaman Rempah dan Obat Biotropika Jurnal Aplikasi Bisnis dan Manajemen (JABM) E-Journal Jurnal Sumberdaya Hayati Majalah Obat Tradisional BERITA BIOLOGI JURNAL HAMA DAN PENYAKIT TUMBUHAN TROPIKA Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi) INDONESIAN JOURNAL OF ESSENTIAL OIL Al-Kimia Acta Pharmaciae Indonesia : Acta Pharm Indo Jurnal Aplikasi Teknologi Pangan Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology Indonesian Journal of Chemistry Majalah Ilmiah Biologi BIOSFERA: A Scientific Journal Biosaintifika: Journal of Biology & Biology Education Jurnal Teknik Pertanian Lampung (Journal of Agricultural Engineering) Jurnal Aplikasi Teknologi Pangan Journal of Tropical Crop Science Acta Biochimica Indonesiana Seminar Nasional Lahan Suboptimal Molekul: Jurnal Ilmiah Kimia Jurnal Ilmu dan Teknologi Kayu Tropis Jurnal Ilmu Kefarmasian Indonesia Jurnal Jamu Indonesia JURNAL MEDIA KESEHATAN Kumawula: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Electrical Engineering and Computer Science Buletin Penelitian Tanaman Rempah dan Obat Sains dan Matematika Wood Research Journal : Journal of Indonesian Wood Research Society Wood Research Journal : Journal of Indonesian Wood Research Society Andalasian International Journal of Agricultural and Natural Sciences Proceeding of Mulawarman Pharmaceuticals Conferences Indonesian Journal of Chemical Studies (Indones. J. Chem. Stud.) Jurnal Sylva Lestari Indonesian Journal of Cancer Makara Journal of Science Jurnal Kedokteran Hewan Depik Jurnal Ilmu-Ilmu Perairan, Pesisir dan Perikanan Molekul: Jurnal Ilmiah Kimia Jurnal Tumbuhan Obat Indonesia Policy Brief Pertanian, Kelautan, dan Biosains Tropika Depik Jurnal Ilmu-Ilmu Perairan, Pesisir, dan Perikanan Indonesian Journal of Forestry Research Indonesian Journal of Jamu
Irmanida Batubara
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, IPB University, IPB Dramaga Campus, Bogor 16680, Indonesia. Tropical Biopharmaca Research Center, IPB University, Bogor 16128, Indonesia
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Journal : Al-Kimia

 1 
Gum Benzoin (Styrax benzoin) as Antibacterial against Staphylococcus aureus Asih Gayatri; Eti Rohaeti; Irmanida Batubara
Al-Kimia Vol 7 No 2 (2019): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (474.648 KB) | DOI: 10.24252/al-kimia.v7i2.10581

Abstract

Gum benzoin (Styrax benzoin) is one of nontimber forest product classified into the resin group. The aim of the study was to determine the component from gum benzoin as an antibacterial against Staphylococcus aureus. Indonesian gum benzoin was obtained from North Sumatra and has antibacterial activity against S. aureus with the MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentrationo) values of its ethyl acetic extract of 1.00 mg/mL and 2.00 mg/mL, respectively. Thin layer chromatography (TLC) was used in purification of ethyl acetate extract of the gum benzoin. The active component was detected by TLC contact bioautography. The bands with Rf of 0.21, 0.77, and 0.87 had growth inhibition activity to the S. aureus. The active antibacterial band with Rf of 0.21 was isolated and it could be an alkaloid component.
Perubahan Pola Kromatografi Lapis Tipis Ekstrak Daun dan Batang Teh (Camellia sinensis (L.) Kuntze) yang Menjadi Inang bagi 3 Benalu Berbeda Irmanida Batubara; Lydia Octifani; Jarwadi Budi Hernowo
Al-Kimia Vol 8 No 2 (2020): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v8i2.14764

Abstract

Plants produce primary and secondary metabolite compounds depending on their growth conditions. The tea plant (Camellia sinensis (L.) Kuntze that hosts Loranthus produces different metabolites compared to those not hosting. This study aims to determine the change in the thin layer chromatography pattern (TLC) of leaf and stem tea extract that is the host 3 types of Loranthus tea namely Loranthus atropurpureus, Loranthus cochinchinensis, and Loranthus pentandrus. Leaf and stem tea extracts that host 3 types of Loranthus were separated using TLC with stationary phase of silica gel 60 F254 and the mobile phase of DCM: MeOH: n-hex (48:1:1). Separation results was detected using UV lamps 254 and 366 nm. The changes of the band's area of each extract were determined using software ImageJ. The results showed a change in TLC patterns. The declining band's area was found in bands detected at 366 nm for the host's stem and tea leaves. The increasing band's areawere found on bands detected at 254 nm especially on tea leaves that host. In conclusion, the change in TLC pattern can be used to determine the compounds that change due to tea plants to host and can be alternative utilization.
Minyak Atsiri Kulit Jeruk Sebagai Bahan Obat Hirup Infeksi Saluran Pernapasan Akut (Ispa): Seleksi dan Organoleptik Prototipe Produknya Nisa Lelita Fadilah; Mella Monica; Ria Heni Sigiro; Irmanida Batubara
Al-Kimia Vol 9 No 2 (2021): DESEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v9i2.23686

Abstract

Acute Respiratory Infection (ARI) is an acute inflammation of the upper or lower respiratory tract caused by bacterial, viral, fungal and other parasitic infections. Lemon peels have been reported to contain beneficial compounds such as phenolic compounds and flavonoids. Flavonoids have been reported to have antioxidant, antibacterial, antiviral, anti-inflammatory, anti-allergic and anticancer activities. The review was conducted to select the orange peel from the best type of orange that can be used as an inhaler for people with ARI. National and international journals were selected based on the keywords citrus peel, antibacterial and antiviral. The chemical components reported in the essential oils of various citrus peels were determined and correlated with their related activity as antibacterial and antiviral. This systematic review shows that compounds that have the potential as antimicrobial, antibacterial and antiviral are flavonoids and limonina, these compounds are widely contained in the essential oil of lemon peel. The conclusion of the review shows that lemon peel essential oil has the potential as a raw material for anti-ARI drugs.
Formulation and Characterization of Sungkai Leaf Extract Nanoemulsion Dista, Rama; Larasati, Cindy; Ayuningsih, Sylvia; Anggraeni, Nurah; Batubara, Irmanida
Al-Kimia Vol 10 No 2 (2022): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i2.33482

Abstract

Sungkai (Peronema canescens Jack) leaves are empirically used for various treatments, and their efficacy can be enhanced using nanoparticle technology, especially nanoemulsions. The purpose was to find the best nanoemulsion formula (NES) containing sungkai leaf extract (EDS). Sungkai leaves were extracted with 70% ethanol, and the compounds were determined by liquid chromatography-mass spectrometry. NES was formed by mixing EDS (260, 400, and 530 mg), VCO, tween80, PEG400, soy lecithin, sodium alginate, and deionized water. The NES formed were characterized by particle size, polydispersity index (PDI), zeta potential, pH, viscosity, percent transmittance, and physical stability test. The results showed that EDS contains at least seven compounds, with eupatilin as a dominant compound. The characterization results obtained NES with a particle size range of 270–520 nm with a PDI value of 0.413–0.608. NES was categorized as stable with a zeta potential value of -45.9 to -48.7 mV and no phase separation based on the centrifugation test. NES has a viscosity of about 1.90–2.03 cP, pH 7, and a percent transmittance of 93–98%. The best formula is the formula with EDS F1 (260 mg). Thus, NES has the potential for the development of multiple treatment targets.
Active Compounds in Broadleaf Mahogany (Swietenia macrophylla) Seeds as Antiaging Agent Based on Molecular Docking Study Batubara, Irmanida; Aulia Putri, Faradina; Tohir, Dudi; Fira Asoka, Shadila
Al-Kimia Vol 11 No 1 (2023): JUNE
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v11i1.37700

Abstract

The appearance of brown spots and wrinkles can be a sign of aging which can increase the risk of cancer. Compounds in broadleaf mahogany seeds (Swietenia macrophylla) contains many compounds and is known to have anticancer activity. The purpose of this study was to determine the compounds in the seeds of these plants have the potential to antiaging by analyzing their molecular docking interaction on the MMP-1 enzyme (matrix metalloproteinase), NEP (neprilysin), PPO3 (polyphenol oxidase), and as a support for the search for anticancer compounds. Two compounds that have the potential as strong inhibitors towards MMP-1 and PPO3 enzymes, namely β-cytostenone and 3β-hydroxystigmast-5-en-7-on which is a steroid group, as well as germacrena A and germacrena D which are terpenoids. Only compound 3β-hydroxystigmast-5-en-7-on which has the potential as a strong inhibitor of the NEP enzyme. All compounds have the potential to be strong inhibitors according to the Lipinski rule. Only compounds which binds to the PPO3 enzyme which has better activity than natural ligand based on ΔG and Binding Site Similarity (BSS) values.
Co-Authors . TRIVADILA Ade Heri Mulyati, Ade Heri Adi Santoso Adi Santoso Afriyanti , Ani Agung Prasetyo Agustin Sri Mulyatni Ahmad Izuddin Aini Fazriani Ainun Nasution Akhirudin Maddu Ali Mahmoud Muddathir Ali Mahmoud Muddathir Alifian Ariansyah Alzamori, Winda Amalia Prihaningsih Ananda, Fira Angga Crystal Loasana Yami Anggraeni, Nurah Anissa Permatasari Anisya Elsa Shafira Anne Carolina Annisa Permata Sari Anthony Nyangson Steven Apriza Yuswan Ariansyah, Alifian Arif Rakhman Hakim Arif Rakhman Hakim Arifin, Poppy F. Arinana Arinana Arista, Galih Saputra Arnold Patogi Siahaan Arnold Patogi Siahaan Asih Gayatri Asoka, Shadila Fira Asti Yosela Oktaviana Audah, Kholis Abdurachim Aulia Putri, Faradina Auliya Ilmiawati Ayu Rahmania Lestari Ayuningsih, Sylvia Azis, Sandra Badrunanto, Badrunanto Baiq Ayu Aprilia Mustariani Bambang Pontjo Priosoeryanto Batubara, Razethy Behling, Hermann Budi Arifin Budiarti, Eka Budiarti, Eka Cahya Septyanti Cahya, Hanifah Dwi Catharina Lopolisa Cece Sumantri Cecep Kusmana Christy Efiyanti Cindy Larasati, Cindy Cinta Badia Br Ginting, Rohani Dadang Muhammad Hasyim Daniel Happy Putra Dea Nurafifah Dea Nurafifah Decsa Medika Hertanto Dedi Fardiaz Devi Aristyanti Dewi, Trisni Dhieka Avrilia Lantana Diah Pamungkas Dikhi Firmansyah Dilaika Septorini Dina Ragillia Sari Diposani, Diva Putri Dista, Rama Djoko Santoso Djoko Santoso Dodi Nandika Dona Octavia Dudi Tohir Dwi Retnowati Dyah Iswantini DYAH PERWITASARI -FARAJALLAH Edi Mirmanto Egra, Saat Eka Budiarti Eka Budiarti Eka Winarni Sapitri Elza Wijaya Endang Kintamani Endang Prangdimurti Endar Marraskuranto Eni Sumarni Eni Sumarni Enny Rimita Sembiring Epi Taufik Erma Suryanti Erna Subroto Erniati Erniati Erniati Eti Rohaeti Eti Rohaeti Evi Kurniawaty Evie Nihayah Evul Winoto Evul Winoto Failasufa, Adzkia Faiza, Lucky Lia Farhana Halimah Rusyda Fazriani, Aini Febriani, Elsa Fendy Fikry Awaluddin Fikry Awaluddin Fikry Awaludin Fiqa Annisa Rakhmatika Fira Asoka, Shadila Folkes Laumal Folkes Laumal Fransiska Devy Junardy Gunawan, Fransisca Gustini Syahbirin Handika Dwi Prasetyo Herry Suhardiyanto Hunaefi, Dase Husnawati, . I Nyoman Pugeg Aryantha Imelda Imelda Indah D. Dewijanti Indrawan, Dikky Indri Yati Intan Noviarni Irene, Angelina Irma Herawati Suparto Irma Hermawati Suparto Irma Isnafia Arief Irma Suparto Izuddin, Ahmad Izza Firdausi Hadiyanto Jahnk, Svea Lina JARWADI BUDI HERNOWO Julkipli Julkipli Julkipli Julkipli, Julkipli Junardy, Fransiska Devy Khalida Shabiba Nursyamsi Kholis Abdurachim Audah Kholis Abdurachim Audah Kilala Tilaar Kosei Yamauchi Kurniawaty, Evi Kuroki, Yutaka Latifah Darusman Latifah K Darusman Latifah K Darusman Latifah K Darusman Latifah K Darusman latifah K Darusman Latifah Kosim Darusman LATIFAH KOSIM DARUSMAN Latifah Kosim Darusman Latifah Kosim Darusman LATIFAH KOSIM DARUSMAN Lela Mukmilah Yuningsih Leti Sundawati Lina Karlinasari Lucia Dhiantika Witasari Lucia Dhiantika Witasari, Lucia Dhiantika Lucky Lia Faiza Luky Adrianto Lutfia Mutmainnah Luthfiana, Widya Lydia Octifani M. Rafi Maily Mustofa Mardho Tillah Mardho Tillah Mardho Tillah, Mardho Martini Ndamunamu Mashuri Waite Mashuri Waite Maulana, Faizal Mawasti, Titi Mella Monica Mohamad Gazali Mohamad Rafi Mohamad Solahudin Morina Adfa Muddathir, Ali Mahmoud Muhamad Nursid Muhammad Ana Syabana Muhammad Asril Muhammad Eka Prastya Muhammad Eka Prastya Muhammad Eka Prastya Muhammad Farid Muhammad Farid Muhammad Nursid Muhammad Nursid Mujahidah, Ummahatul Mulya Sari Mulyatni, Agustin Sri Munawaroh, Fauziyatul Mustofa, Maily Mutia Ramadani Nadia Prilliane Putri Nadiah, Nur Syafiqah Nadila Fany Ashafani Nampiah Sukarno Nancy Dewi Yuliana Nevianti Zamany Neviaty P Zamani NEVIATY PUTRI ZAMANI Nina Ratna Djuita Ning Ima Arie Wardayanie, Ning Ima Arie Ninuk Purnaningsih Nisa Lelita Fadilah Nisa, Ulfiatun Novita Ariani NUNIK SRI ARIYANTI Nur Syafiqah Nadiah Mohammad Rafi Nurheni Wijayanto Nurlela Nurlela Nursyamsi, Khalida Shabiba Nuzulia, Nur A Pamungkas, Diah Pamungkas, Diah Daru PAMUNGKAS, DIAH DARU Poppy F. Arifin Prayogo, Yanico Hadi Priyadi, Yogo Suro Purwantiningsih Sugita Putri Utami, Putri Putri, Nadia Prilliane Rachmayanti, Yanti Rahadyanoto Trimulia Rahmi Nur Wahidah Rahmi Utami Rahminiwati, Min Rakhmat, Asep Rakhmatika, Fiqa Annisa Raphael Aswin Susilowidodo Ratte, Marina Razethy Batubara Refilda Refilda Rerenstradika Tizar Terryana Reza Ro'isatul Umma Ria Heni Sigiro Riana, Elisa Nurma Rika Indri Astuti RIKA RAFFIUDIN Rikno Harmoko Rita Kartika Sari Rohani Cinta Badia Ginting Rohayati Suprihatini ROHAYATI SUPRIHATINI Romi Irka Putra Rosalina Wisastra Rosalina, Dian S.Pd. M Kes I Ketut Sudiana . Saat Egra Saat Egra Saat Egra SAEPUDIN RAHMATULLAH Saifanah Setiawan, Nabilah Salina Febriany Sandra Arifin Aziz Sari, Dina Ragillia Sari, Yessie W Sastia Prama Putri Sayusti, Tiara Setyanto Tri Wahyudi Shadila Fira Asoka Shadila Fira Asoka Shafira Ananda Djakaria Shafira, Anisya Elsa Siahaan, Arnold Patogi Sihegiko Kanaya Silmi Mariya SILMI MARIYA Sintho Wahyuning Ardie Siswoyo Siswoyo SITI SA’DIAH Sitompul, Rahmadi Slamet Widodo Slamet Widodo Soekisman Tjitrosoedirdjo Sri Listiyowati Sri Nurdiati Sri Purwanti Sri Purwanti Sri Purwanti Sri Sugiarti Sri Wahyuni Sri Wilarso Budi Steven, Anthony Nyangson Stevia Septiani Subroto, Erna SUHARINI, YUSTINA SRI Suharti, Sri SUMINAR S. ACHMADI SUMINAR SETIATI ACHMADI Suparto, Irma Suparto, Irma Supriyanto Supriyanto Supriyanto Susilowidodo, Raphael Aswin Takemori, Hiroshi Tamsin, Aqlia Hanna Nurfatiha Taopik Ridwan Taopik Ridwan Taopik Ridwan Tatang Tiryana Taufik Ridwan Taufik Ridwan, Taufik Tilaar, Kilala Tintin Sarianti Titi Mawasti Tjandrawati Mozef Tohir, Dudi Tohru Mitsunaga Tohru Mitsunaga Tohru Mitsunaga Tohru Mitsunaga Trisni Untari Dewi Tunnisa , Fitra Ummi Zahra, Ummi Upik Kesumawati Hadi Uswatun Hasanah Utami Dyah Syafitri Utut Widyastuti Valentina Sokoastri Valentina Sokoastri Veby Tri Yani Veby Tri Yani Vera Permatasari Wahyuni, *Wulan Tri Wahyuni, Wulan T Waras Nurcholis Wasrin Syafii Wati, Vivi Septya Wijaya, Elza Winanda, Witri WINDRA PRIAWANDIPUTRA, WINDRA Wisastra, Rosalina Wisnu Ananta Kusuma Witri Winanda Wulan Tri Wahyuni Yamauchi, Kosei Yana Rubiyana Yana Rubiyana, Yana Yanico Hadi Prayogo Yanti Rachmayanti Yefrida Yefrida Yessie Widya Sari Yogo Suro Priyadi Yudiwanti Yudiwanti Wahyu E. Kusumo Yuliana Galih Dyan Anggraheni YULIN LESTARI Yuni Kartika Yuni Kartika, Yuni Yusuf Ryadi Yuyun Nisaul Khairillah Zaenal Abidin Zamany, Nevianti Za’aziza Ridha Julia Zuraida Hanum Zuraida Hanum Zuraida Hanum