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Indra Saputra
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Journal : Paediatrica Indonesiana

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Validation of PELOD-2 score as a predictor of life-threatening organ dysfunction in pediatric sepsis Yuyun Romaria Simanjuntak; Indra Saputra; Silvia Triratna; Achirul Bakri; Yulia Iriani
Paediatrica Indonesiana Vol 60 No 5 (2020): September 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi60.5.2020.227-32

Abstract

Background The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined sepsis as life-threatening organ dysfunction due to immune dysregulation against infection. It recommends the Sequential (sepsis-related) Organ Failure Assessment (SOFA) score to evaluate life-threatening organ dysfunction. But the SOFA tool has not been adjusted for pediatric patients. The Indonesian Pediatrics Society (IPS) uses the same sepsis definition and recommends using the PELOD-2 score as an indicator of life-threatening organ dysfunction in children. Objective To evaluate the validity of the PELOD-2 score for predicting life-threatening organ dysfunction in pediatric sepsis. Methods A prospective cohort study was conducted in children with sepsis who were admitted to the PICU. Subjects were taken consecutively with inclusion criteria of 1 month-18 years of age, with organ dysfunction, having two or more symptoms of systemic inflammatory response syndrome (SIRS), and suspected or proven infection. PELOD-2 score, with and without lactate result, of each subject were plotted to receiver operating characteristic (ROC) curve, then we determined the most optimal cut off point to predict the life-threathneing organ dysfunction in pediatric sepsis based on the sensitivity and specificity of each score. Results Sixty-six patients were analyzed, with 40 males and 26 females aged 2 to 183 months (median 11 months). Twenty patients died while in the PICU. A PELOD-2 score (with lactate) cut-off ≥ 7 was determined by ROC curve, with sensitivity of 80% and specificity of 78%. The area under the curve (AUC) of PELOD-2 score (with lactate) was 84.8% (95%CI 74.7 to 95.9%). A PELOD-2 score (without lactate) ≥ 7 was the most optimum cut off based on its Youden index, it haD 70% of sensitivity and 80% of specificity. Conclusion PELOD-2 score ≥ 7 , with or without lactate component is the optimal cut-off for predicting life-threatening organ dysfunction in pediatric sepsis.
Medical and non-medical factors associated with stunting in infants and toddlers aged 3-59 months in Palembang Elsi, Yuanita Rimadini; Fauzi, Moretta Damayanti; Anzar, Julius; Indra, Raden Muhammad; Yosy, Deny Salverra; Saputra, Indra; Ramadanti, Afifa
Paediatrica Indonesiana Vol. 65 No. 1 (2025): January 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.1.2025.16-24

Abstract

Background Although the prevalence of stunting in South Sumatera is estimated to be relatively high, there have been few studies to date on stunting and the factors associated with it in the region. Objective To determine the proportion of stunting in infants and toddlers aged 3-59 months at Mohammad Hoesin General Hospital (RSMH), Palembang, South Sumatera, and to identify medical and non-medical factors associated with stunting in these children. Methods A cross-sectional study was conducted at RSMH from April to September 2023. Stunting was defined according to the WHO standard and combined with a growth pattern that reflects chronic malnutrition. We recorded the proportion of stunting as well as data on several potential medical and non-medical risk factors of stunting. Results A total of 183 subjects met the inclusion criteria. The overall proportion of stunting was 65/183 (35.5%). The proportion of stunting was higher in boys (39.6%) and in children <2 years of age (38.2%). Medical risk factors significantly associated with stunting were infectious disease [OR 4.13 (95%CI 1.91 to 8.94); P=0.001] and chronic disease [OR 3.02 (95%CI 1.56 to 5.85); P=0.001]. The only non-medical factor significantly associated with stunting was low paternal education level [OR 2.45 (95%CI 1.17 to 5.15); P=0.016]. Conclusion During the study period, over a third of pediatric patients at RSMH experienced stunting. Infectious disease, chronic disease, and low paternal education level were significant risk factors that contributed to the occurrence of stunting.
Co-Authors A. Gofar Sastrodiningrat Achirul Bakri Adam Rasyid Sidiqi Adinda Zahra Afiffah Afifa Ramadanti Agustina, Ruslinda Ahmad sulthon Nasyir Aidil Alfin Akbar Septiawan Akmal, Yuliandri Alfin, Aidil Ali, Rahman Anak Agung Istri Sri Wiadnyani Andani, Mega Andiko, Yandri Andini Angga Rizki Prawira Anggraini , Nadia Angin, Beatrice Perangin Aniati, Ira Annisah Zaeri Anugerah Wijayaputra Japar Apriani Apriani Apriza Apriza, Apriza Ardi, Frans Guntara Arie Rahman, Muhammad Arief Kurniawan Ariyani, FharaDita Ayda Murni Azzahra Sairi, Fathya Azzahra, Ghiatsya Bawiling, Hendry Bonyah, Ebenezer Choironi, Merry Dalimunthe, Dermina Damajanti, Heny Danny, Ramanda Daulay, Irmasani David Immanuel Dealank, Reynant Phaza Deny Salverra Yosy, Deny Salverra Desi Isnaini Dewi Murni Dewi Safitri Dewi, Siska Miga Efrianova, Vivi Eli Febriani Elsi, Yuanita Rimadini Elviza Yeni Putri Erina Mateluni Etty Murwaningsari Fauzi, Moretta Damayanti Febri Silvia Fitri Nur Ashari Ghozali, Ahmad Gunawan Tabrani Guzeynova, Monica Zabrina Hakim, Lukmanul Hanifah Hanifah Hariko, Rezki Hasibuan, Nurhayya Putri Haskas, Yasir Hastuty, Milda Hayatunnufus Hayatunnufus Hendra Hendra Hidayah, Zhiratul Hidayanti, Eka Nur Hidayat, Nabila Aurelia Hikmayanti, Hikmayanti Hurriyatus Sa'adiyah Hutasuhut, Nurul Inayah Ika Puspitasari Indra, Raden Muhammad Indra, Yetti Afrida Ishak Ishak Juanda Nawawi, Juanda Julius Anzar, Julius Karmila Sari khairani, afdila Kurniawan Kurniawan Kusumastuti, Dyah Kusumastuti, Dyah Laila Putri, Tiara Lasmi, Nadia Leon, Farah Margaretha Lestari, Ayu Eka Lestari, Henny Setyo Lutfiah Azzahrah Nur maidi, asdita Mardi Yati Marina Angraini, Lilis Masrianti Fadillah Mega Andani Mega Andini Melda Mahniza Meywanthi, Nindha Iqlima Muhammad Nadif Muhammad Ridha Muhammad Yusuf Salam Mukhbita, Alya Mulyani, Lili Mulyani, Susi Dwi Murdani, Riski Murni Astuti Mutiara , Rizky Indah Nadia Nurani Isfarin Najla Salsabilla Zelyantie Nara Pranata Deviona Nasir, Alfian Natania, Mega Lefina Netrawati, Netrawati Ningsih , Siska kartika Ningsih, Siska Kartika Nur Hidayah, Selvia Nurhaswinda Nurwijayanti Oktarina, Rahmi Opi Teci Darisma Putri, Opi Teci Pakpahan, Tauhid Pania Putri, Riska Perangin Angin*, Frederick Nicholas Piki, Piki Puji Hujria Suci Purwanto Putri Adona Putri Hana Pebriana Putri, Fidella Eriza Putri, Mutia Raden Mohamad Herdian Bhakti Rafael Aginta S. Brahmana Rahmadini Fitri Rahmatul Laili Rahmatullah Rahmatullah Rahmiati Rahmiati Rahmiati Ramadhan SY, Taufik Ranny Mukerdi Rara Gustiana rauzati, nursandrina Rensa Rensa Riezkiana, Frieshella Ananda Rifanda, Firara Rifka Haida Rahma Riska Pania Putri Ritonga, Fashya Syahrani Rokhim, Minatur Rosalina, Linda Rosalinda, Linda Sa'adiyah, Hurriyatus Saemona, Indra Safira, Nazwa Safitri, Juleha Salman Alfarisi Sapitri, Roni Sari, Resti Elma Sari, Syakira Kurnia Sartika, Ayu Sayuti, Muhammad Sazabilla, Mutiara Tasya Sa’adiyah, Hurriyatus Sekar Mayangsari Septiawan, Akbar Silvia Triratna Silvia, Febri Siti Hajar Thaitami Siti Mariyam Siti Mulyani Siti Nurhayati Sitompul, Tresia Agustina Soraya, Rolin Sri Ratna S SRI WAHYU UTAMI sriwahyuni Sriwahyuni Stevano, Nandito Stevi Andreanus Suari, Oppie Dini Sugeng Rianto Sumarno Susanti Yusman, Ana Suwarno Suwarno Suzy Indharty SY, Taufik Ramadhan Syahputra, Muhammad Vischal Taqwa, Mutiara Tengku Abdani Murazanty Tessa Aida Trisna Triswandari, Retno Vanessa Surya Veny, Veny Vici Syahril Khairani Vitri Tundjungsari Wanti, Hilda Widodo, Deny Edy Wika Tri Lestari Yanita, Merita Yansyah, Dedi Yeni Elviza Febrianti Yeni Karneli Yetti Afrida Indra Yolanda Yolanda, Yolanda Yulia Iriani Yunita, Siti Marini YUPELMI, MIMI Yusri, Dairina Yuyun Romaria Simanjuntak Zadrian Ardi Zahiyah, Adibah Bahirah Zahra, Naila Az Zahrah, Azizah Zida Naela Salsabilla