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Dampak Gizi pada Perkembangan Kognitif Anak: Kajian Literatur dan Temuan Baru Afni, Fauza; Setianti, Yanti; Novilla, Arina; Hudzaifah, Hindun Mila; Rita, Rauza Sukma
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 3 No. 2 (2022)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

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Abstract

Perkembangan kognitif anak-anak adalah aspek penting dalam tahap pertumbuhan mereka, yang dapat dipengaruhi oleh berbagai faktor termasuk gizi. Artikel ini bertujuan untuk menyelidiki dampak gizi pada perkembangan kognitif anak-anak melalui tinjauan literatur yang mendalam dan penyajian temuan baru. Kami melakukan pencarian literatur yang cermat untuk mengidentifikasi penelitian-penelitian terbaru yang berkaitan dengan hubungan antara gizi dan perkembangan kognitif anak-anak. Dalam artikel ini, kami merangkum hasil penelitian yang mendukung hubungan positif antara asupan gizi yang baik dan perkembangan kognitif yang optimal pada anak-anak. Kami juga menyajikan temuan baru yang menggarisbawahi pentingnya nutrisi yang tepat dalam tahap-tahap kritis perkembangan kognitif. Kami menyoroti peran nutrisi kunci, seperti asam lemak omega-3, vitamin dan mineral tertentu, dalam perkembangan kognitif anak-anak. Selain itu, kami membahas implikasi kebijakan dan praktik gizi yang dapat membantu meningkatkan perkembangan kognitif anak-anak. Penelitian ini memberikan wawasan yang berharga bagi orangtua, pendidik, dan profesional kesehatan dalam memahami pentingnya nutrisi dalam mendukung perkembangan kognitif anak-anak. Temuan baru dalam penelitian ini dapat menjadi landasan bagi peningkatan program-program gizi dan intervensi yang bertujuan untuk memaksimalkan potensi kognitif anak-anak.
Pengembangan Terapi Imunologi Personalisasi dalam Pengobatan Kanker: Tantangan dan Prospek Al Farisy, Alexandria Firdaus; Fadli, Fadli; Sihite, Perdana Liansyah; Ginting, Kevin Hizkya; Rita, Rauza Sukma
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 3 No. 2 (2022)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

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Abstract

Pengembangan terapi imunologi personalisasi telah menjadi fokus utama dalam penelitian pengobatan kanker karena potensinya dalam meningkatkan respons tubuh terhadap sel kanker. Artikel ini membahas tantangan dan prospek dalam pengembangan terapi imunologi personalisasi untuk mengatasi kerumitan heterogenitas kanker. Terapi imunologi personalisasi melibatkan pendekatan yang dirancang khusus untuk merangsang sistem kekebalan pasien agar mengenali dan melawan sel kanker secara spesifik. Salah satu tantangan utama dalam pengembangan terapi ini adalah keragaman mutasi genetik dan ekspresi antigen pada setiap tumor kanker. Penelitian genomik dan pemetaan antigen spesifik tumor menjadi langkah kunci untuk merancang terapi yang sesuai dengan karakteristik unik setiap pasien. Selain itu, resistensi terapi dan potensi efek samping memerlukan pemahaman mendalam terhadap interaksi kompleks antara sel kanker dan sistem kekebalan. Meskipun tantangan tersebut, terdapat prospek yang menjanjikan. Kemajuan dalam teknologi sekuensing genom, pemodelan bioinformatika, dan pemahaman lebih lanjut terhadap mekanisme regulasi sistem kekebalan telah memberikan dasar bagi pengembangan terapi imunologi personalisasi. Terapi ini memungkinkan pemberian pengobatan yang lebih efektif dan minim efek samping karena disesuaikan dengan profil genetik dan antigen spesifik pasien. Dalam konteks ini, artikel ini juga membahas sejumlah strategi pengembangan terkini, seperti penggunaan vaksin terapeutik dan terapi sel T berbasis CAR (Chimeric Antigen Receptor), yang memberikan harapan baru dalam meningkatkan respons imun terhadap kanker. Dengan memahami tantangan dan prospek tersebut, artikel ini memberikan wawasan mendalam terkait pengembangan terapi imunologi personalisasi sebagai pendekatan yang menjanjikan dalam mengatasi kompleksitas pengobatan kanker.
Perineal Massage on the Prevention of Perineal Lacerations Among Maternity Mothers : A Literature Review Utami, Riezka Putri; Yulizawati; Hardisman; Firdawati; Rita, Rauza Sukma; Lisa, Ulfa Farrah; Iffah, Uliy
Women, Midwives and Midwifery Vol. 4 No. 2 (2024): Women, Midwives and Midwifery journal
Publisher : Asosiasi Pendidikan Kebidanan Indonesia (AIPKIND)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36749/wmm.4.2.43-55.2024

Abstract

Background: Childbirth is a physiological process, which is ended by removal of the fetus, placenta, and membrane from the uterus in full-term pregnancy without action and complications. During the childbirth there are complications that can cause death, one of which is the case of perineal lacerations. Perineal massage is an action that can be done to prevent the occurrence of perineal lacerations in maternity mothers.   Purpose: This study aims to determine perineal massage on the prevention of perineal lacerations in maternity mothers. Methods: This research method was a literature review study. Journal searches were carried out by applying online database such as Sciencedirect, PubMed, Scopus, Google Scholar, Semantic Scholar, and Portal Garuda. Articles were selected based on inclusion and exclusion criteria. Results: The analysis was carried out on 18 research articles. It was found that perieneal massage can cause vasodilation of blood vessels so that blood flow to the perineum increases so that the perineal area becomes more elastic. The application of perineal massage is able and effective in preventing and reducing the incidence of perineal lacerations in maternity mothers. Conclusion: The influence of perineal massage is useful in the prevention of perineal lacerations in maternity mothers.
Narative Review The Effect of Endorphin Massage and Counter Pressure During Labor On Endorphin Hormone Release Rizal, Wadratul Jannah; Yulizawati, Yulizawati; Hardisman, Hardisman; Firdawati, Firdawati; Rita, Rauza Sukma
Women, Midwives and Midwifery Vol. 4 No. 2 (2024): Women, Midwives and Midwifery journal
Publisher : Asosiasi Pendidikan Kebidanan Indonesia (AIPKIND)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36749/wmm.4.2.56-72.2024

Abstract

Background: Labor pain is a subjective experience associated with uterine contractions, stretching of the cervix, and descent of the fetal head. According to the World Health Organization (WHO), every year, 210 million pregnancies occur in the world, and 20 million women experience pain due to childbirth. Of the 2700 mothers giving birth, 30% experienced severe pain, 20% of labor was accompanied by very severe pain, and 15% experienced mild pain. Non-pharmacological therapy continues to be developed in the world of obstetrics, which aims to provide comfort during the birthing process. Endorphin massage and counter pressure are non-pharmacological therapies that can stimulate the release of endorphins and reduce pain and anxiety during childbirth. Objective: This study aims to determine the effect of endorphin massage and counter pressure during labor on the release of endorphin hormones and their benefits. Methods: This research method was a literature review study. Journal searches were carried out by applying online databases such as PubMed, Garuda Portal, ScienceDirect, and Google Scholar. Articles were selected based on inclusion and exclusion criteria. Results: The analysis was carried out on 32 research articles. It was found that endorphin massage and counter pressure are non-pharmacological techniques to overcome and reduce labor pain and anxiety through the help of endorphin hormones which are useful for a smooth delivery process. Conclusion: The influence of endorphin massage and counter pressure during labor on the release of endorphin hormones, which are useful for reducing labor pain, reducing anxiety, increasing comfort, and speeding up the labor process.
Factors Associated with The Incidence of Chronic Energy Deficiency (CED) n Third Trimester Pregnant Women In The Working Area of The Lubuk Begalung Health Center, Padang City Agustianov, Indah; Lestari, Yuniar; Lisa, Ulfa Farrah; Rita, Rauza Sukma; Hudzaifah, Hindun Mila
Women, Midwives and Midwifery Vol. 4 No. 3 (2024): Women, Midwives and Midwifery journal
Publisher : Asosiasi Pendidikan Kebidanan Indonesia (AIPKIND)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36749/wmm.4.3.93-106.2024

Abstract

Background: The World Health Organization (WHO) reports a global prevalence of Chronic Energy Deficiency (CED) in pregnancy ranging from 35-75%. In Padang City’s Lubuk Begalung Region, the 2022 health profile indicated a 12.9% incidence of CED among 1,268 pregnant women. Several factors influence CED incidence, including age, economic status, education, pregnancy spacing, parity, employment, and antenatal care (ANC) visits. Purpose: To identify factors associated with CED among third-trimester pregnant women in the Lubuk Begalung Health Center Working Area. Methods: This cross-sectional analytical study involved 57 respondents selected through simple random sampling. Inclusion criteria were third-trimester pregnant women aged 24-40 weeks who could communicate effectively, excluding those who could not be contacted after three attempts. Data collection involved interviews using a structured questionnaire, and analyses were performed using chi-square and logistic regression with a 95% confidence interval. Results: CED was observed in 21 respondents (36.8%). Key factors included age <20 or >35 years (59.3%), low economic status (55.0%), low education level (53.8%), unemployment (51.5%), and ?3 ANC visits (56.5%). Age was the dominant factor (p = 0.005, b = 6.623). Conclusion: Age, education, occupation, and ANC visits were significantly associated with CED, while economic status, pregnancy spacing, and parity were not. Future studies should explore additional factors influencing CED.
Pengaruh Pemberian Mesenchymal Stem Cell Wharton's Jelly Terhadap Aktivitas Enzim Katalase pada Tikus Wistar Model Hiperglikemia Ramadhani, Dhea Amaliya; Endrinaldi; Putri, Biomechy Oktomalio; Rita, Rauza Sukma; Mahata, Liganda Endo; Dian Pertiwi
Majalah Kedokteran Andalas Vol. 48 No. 2 (2025): MKA April 2025
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v48.i2.p117-124.2025

Abstract

Objective: To determine the effect of Wharton's Jelly (MSC-WJ) mesenchymal stem cells on the activity of the catalase enzyme in hyperglycemic Wistar rats. Methods: This study used 21 male Wistar rats aged 2-3 months with a body weight of 200-300 grams according to the inclusion and exclusion criteria. Mice were divided into 3 groups: negative control (K-), positive control (K+), and treatment (P). Group K- was only given food and drink without being given treatment. The K+ group was injected intraperitoneally with alloxan at a dose of 100 mg/kg BW so that the rats became hyperglycemic. Group P was given an alloxan injection and left for a week, then given MSC-WJ 3x106 cells through the tail vein and left for four weeks. After four weeks, all groups had their blood taken to examine the catalase enzyme. Result: Mean of catalase activity enzyme in the K-, K+, and P groups were 4.22 ± 0.27 units/mg, 2.39 ± 0.19 units/mg, and 3.93 ± 0.45 units /mg, respectively. Conclusion: This shows that the administration of mesenchymal stem cells Wharton's Jelly (MSC-WJ) has an effect on increasing the serum catalase enzyme activity of Wistar rats with hyperglycemia models.
EFFECT OF BABY MASSAGE AND KANGAROO MOTHER CARE TO WEIGHT GAIN ON LOW BIRTH WEIGHT (LBW) Arief, Windhy Lathifah; Rita, Rauza Sukma; Oktova, Rafika
Indonesian Journal of Health Science Vol 8 No 2 (2024): September
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/ijhs.v8i2.6813

Abstract

Babies with low birth weight (LBW) require more complex treatments. Baby massage and kangaroo method treatment are additional treatments that can be given so that babies experience weight gain. Weight gain is an indicator of growth in babies with LBW. This study aims to determine the effect of infant massage and kangaroo methods on weight gain in LBW babies. Method: Narrative literature review through databases: ScienceDirect, PubMed and Google Scholar using inclusion and exclusion criteria. Results: 20 journals were obtained for analysis. Baby massage carried out by parents for 7 days (3 times a day, for 15 minutes) affected weight gain in low birth weight babies with an average weight gain of 15 grams/day. The kangaroo method, for a minimum of 4-6 hours and carried out directly by the baby's mother, had a more significant effect on weight gain in low birth weight babies with an increase of 6 grams/day. Infant massage interventions and kangaroo methods also had a better effect on weight gain in babies with low birth weight with an average weight gain of 11-23 gr/day. This study concludes that infant massage and kangaroo methods affect weight gain in babies born with LBW.
PEMANFAATAN APLIKASI CANVA DALAM PENYUSUNAN MEDIA PEMBELAJARAN BERBASIS TEKNOLOGI Rahmawati, Lailia; Suharni, Suharni; Ambulani, Nur; Febrian, Wenny Desty; Widyatiningtyas, Reviandari; Rita, Rauza Sukma
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 1 (2024): Volume 5 No 1 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i1.24151

Abstract

Pengabdian masyarakat ini bertujuan untuk meningkatkan keterampilan desain grafis para pendidik melalui pemanfaatan aplikasi Canva dalam penyusunan media pembelajaran berbasis teknologi. Kegiatan dilaksanakan pada 14 Desember 2023 melalui platform Zoom, melibatkan 32 peserta dari berbagai latar belakang pendidikan. Metode kegiatan mencakup persiapan, presentasi teori, demonstrasi praktis, serta sesi praktik bersama. Hasilnya mencakup peningkatan keterampilan desain grafis, pemahaman konsep desain visual, dan kemampuan peserta dalam menciptakan media pembelajaran yang berkualitas. Kegiatan ini juga membentuk jaringan dan komunitas antar peserta.
Pengaruh Pemberian Kukis Kombinasi Tepung Ikan Tongkol (Euthynnus affinis) dan Tepung Bayam (Amaranthus tricolor) Dengan Penambahan Probiotik Dadih Terhadap Kadar Feritin Serum Pada Tikus Wistar Anemia Azahra, Azizah Firda; Lipoeto, Nur Indrawaty; Rofinda, Zelly Dia; Rita, Rauza Sukma; Desmawati, Desmawati; Yulia, Dwi; Fasrini, Ulya Uti
SENTRI: Jurnal Riset Ilmiah Vol. 4 No. 11 (2025): SENTRI : Jurnal Riset Ilmiah, November 2025
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/sentri.v4i11.4950

Abstract

Anemia is a global health problem characterized by low hemoglobin and ferritin levels due to iron deficiency, which affects growth, cognition, and disease risk, particularly in children and women of reproductive age. Local food–based nutritional interventions such as skipjack tuna (heme iron), spinach (non-heme iron), and dadih (probiotics) have the potential to provide synergistic effects in improving iron status. This study aimed to determine the effect of cookies made from a combination of skipjack tuna flour and spinach with the addition of dadih probiotics on serum ferritin levels, as well as the effectiveness of Sodium Nitrite (NaNO₂) in decreasing ferritin and hemoglobin levels as indicators of anemia. The study used a Post-Test Only Control Group design with 36 female Wistar rats induced with anemia using NaNO₂ at a dose of 25 mg/200 g BW for 18 days, then divided into six treatment groups for 28 days. Ferritin levels were measured using the ELISA method. The results showed that administering cookies made from the combination of skipjack tuna flour and spinach with dadih probiotics significantly increased ferritin levels (P=0.000) compared to the control and single-ingredient groups. NaNO₂ was proven effective as an anemia-inducing agent. This combined cookie formulation has the potential to improve serum ferritin levels.
DAMPAK GIZI PADA PERKEMBANGAN KOGNITIF ANAK: KAJIAN LITERATUR DAN TEMUAN BARU Afni, Fauza; Zulfan Zulfikar; Nur Rohmah; Muhammad Toat; Rauza Sukma Rita
Jurnal Cahaya Mandalika ISSN 2721-4796 (online) Vol. 6 No. 3 (2025)
Publisher : Institut Penelitian Dan Pengambangan Mandalika Indonesia (IP2MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/jcm.v6i3.4561

Abstract

Children's cognitive development is an important aspect in their growth stage, which can be influenced by a variety of factors including nutrition. This article aims to investigate the impact of nutrition on children's cognitive development through an in-depth literature review and presentation of new findings. We conducted a careful literature search to identify the latest studies relating to the relationship between nutrition and children's cognitive development. In this article, we summarize the results of studies that support a positive relationship between good nutritional intake and optimal cognitive development in children. We also present new findings that underscore the importance of proper nutrition in critical stages of cognitive development. We highlight the role of key nutrients, such as omega-3 fatty acids, certain vitamins and minerals, in children's cognitive development. In addition, we discuss the implications of nutrition policies and practices that can help improve children's cognitive development. This research provides valuable insights for parents, educators, and health professionals in understanding the importance of nutrition in supporting children's cognitive development. The new findings in this study could lay the foundation for improved nutrition programs and interventions aimed at maximizing children’s cognitive potential
Co-Authors Abdiana Abdiana, Abdiana Adilla Oktariza Zarwin Afi Putra Perdana Nurullah Afni, Fauza Afriani, Nita Agustianov, Indah Ahmad Muhtar Al Farisy, Alexandria Firdaus Alhamda, Nadhiyatul Almurdi Almurdi Ambulani, Nur Amel Yanis Amizuar, Yulia Fauziah Amriza, Muhammad Zidan Annisa Annisa Annisa, Nadia Rizki Ansori, Fachrurrazi Al Apriyanto, Mulono Ari Setiawan Ari Susanti Arif Sabta Aji Ariyani, Farida Arum Putri Rahayu Asih Dewi Setyawati Aswiyanti Asri Aswiyanti Asri Azahra, Azizah Firda Azmi, Yudia Azrimaidaliza Azriz, Helena Bobby Indra Utama Budi Witjaksana Cesar, Afifah Raudhati Delmi Sulastri Desmawati Desmawati Desmawati Desmawati Dessy Arisanti Dessy Arisanti Dessy Arisanty Desy Arisanti Desy Arisanti Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Didi Sudrajat Dwi Novrianda Eliza Anas Elly Usman Elmatris Sy Endrinaldi Endrinaldi Endrinaldi Erda Mutiara Halida Eryati Darwin Eti Yerizel Fadli Fadli Faishal Arif Kurniawan Fajri, Rahmi Eka Farida Ariyani Fathiyyatul Khaira Fathiyyatul Khaira, Fathiyyatul Febby Arrahmi Febrian, Wenny Desty Firdawati Firdawati Firdawati Firdawati, Firdawati Fitrayeni Fitrayeni Fitrayeni Fitria, Henni Ginting, Kevin Hizkya Hanum, Fathiya Juwita Hardisman Hasmiwati Hayyumahdania Reswan Helti Lestari Sitinjak Hervina Winerti Hindun Mila Hudzaifah Hirowati Ali Husna Yetti Husnil Kadri Ibrahim, Raihan Syah Iffah, Uliy Ilmiawati Ilmiawati, Ilmiawati Irya, Nada Amelinda Isnindiah Koerniati Jamil, Mohd. Julizar Julizar Julizar Nazar Karmia, Hudila Rifa Kurniawan, Faishal Arif Laila laila Laras Surakusuma Lathifah Arief, Lathifah M Ikhsan Mahata, Liganda Endo Maiyani Lestari Mas'ud Muhammadiah Masrul Maulana, Rafi Mellina Rahmi Miftah Irrahmah Miftah Irramah Miranie Safaringga Mohamad Reza Mohamad Reza Muflihah Isnawati Muhammad Abi Ghoffari Siregar Muhammad Toat Muhammad Zidan Amriza Nada Amelinda Irya Nidya Ikha Putri Nisriinaa Yurensi Novilla, Arina Nur Indrawaty Lipoeto Nur Rohmah Nursal Asbiran Nurullah, Afi Putra Perdana Nuzulia Irawati Pitra, Dian Ayu Hamama Putra Santoso Putri, Biomechy Oktomalio Rafika Oktova Rahayu, Yanti Rahmaddiansyah, Refa Rahmadini Aulia Rahmatini . Rahmawati, Lailia Rahmi, Wahida Ramadhani, Dhea Amaliya Refa Rahmaddiansyah Refa Rahmaddiansyah Refa Rahmaddiansyah Resy Nirawati Reviandari Widyatiningtyas, Reviandari Rika Susanti Rima Semiarty Rina Gustia Ririn Marta Sari Rizal, Wadratul Jannah Rizaldi, Fajri Rusti, Sukarsi Santika, Annisa Yulia Serudji, Joserizal Shoulhuna, Ziadati Sihite, Perdana Liansyah Sisca Dwi Yarni Sri Mulyanti Sri Suparni Suharni Suharni Sukarsi Rusti Sulthani, Muhammad Zhorif Tofrizal Ulfa Farrah Lisa, Ulfa Farrah Ulya Uti Fasrini Utami, Riezka Putri Wahida Rahmi Wahida Rahmi Yanti Setianti Yulia, Dwi Yuliarni Syafrita Yulizawati Yulizawati, Yulizawati Yuniar Lestari Yurensi, Nisriinaa Yusrawati Yusrawati Yustini Alioes Zelly Dia Rofinda Zulfan Zulfikar Zulham Zulham Zurrahmi Wirda