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All Journal Jurnal Gizi dan Pangan Jurnal Gizi Medula Global Medical and Health Communication Jurnal Media Gizi Indonesia (MGI) Jurnal Riset Gizi GIZI INDONESIA AcTion: Aceh Nutrition Journal Argipa (Arsip gizi dan Pangan) JMM (Jurnal Masyarakat Mandiri) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Window of Health : Jurnal Kesehatan Amerta Nutrition QARDHUL HASAN: MEDIA PENGABDIAN KEPADA MASYARAKAT Jurnal Kesehatan Indonesia JURNAL MEDIA KESEHATAN Jurnal Gizi Prima Poltekita : Jurnal Ilmu Kesehatan J-Kesmas: Jurnal Kesehatan Masyarakat (Indonesian Journal of Public Health) Science Midwifery JK Unila (Jurnal Kedokteran Universitas Lampung) Journal SAGO Gizi dan Kesehatan Jurnal Kesehatan Tambusai Journal of Language and Health Jurnal Ilmiah Kesehatan (JIKA) Journal Of Applied Food And Nutrition Jurnal Kesehatan komunitas Indonesia Jurnal Pangan Kesehatan dan Gizi (JAKAGI) Mestaka: Jurnal Pengabdian Kepada Masyarakat Jurnal Keperawatan Profesional (KEPO) Media Pendidikan Gizi dan Kuliner Media Ilmiah Kesehatan Indonesia Jurnal Riset Gizi Jurnal Riset Gizi Journal of Dietetics Science JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Yunianto, Andi Eka
Universitas Lampung
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Journal : Medula

 1 
PENGARUH PEMBERIAN EKSTRAK LADA HITAM (Piper nigrum L) TERHADAP LIBIDO (PERILAKU SEKSUAL) MODEL TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) DIABETES MELITUS Isvari, Gusti Ayu Made Prathita; Hadibrata, Exsa; Yunianto, Andi Eka; Susianti
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1284

Abstract

Abstract Diabetes Mellitus causes complications in the form of sexual libido dysfunction. Some of the treatment for libido dysfunction was aphrodisiac (piperin) which consist in black pepper. This study aimed to determine the effect of black pepper (piper nigrum l) extract on male white rat (Rattus norvegicus) libido (sexual behavior) with diabetes mellitus. The study was an experimental laboratory with a post-test only control group design using 30 samples of male white rats (Rattus norvegicus) which divided into 5 groups. Each divided into, control group 1 (K1) consist of normal rats; control group 2 (K2), diabetic rats induced by alloxan 150 mg/kg; treatment group 1 (P1), diabetic rats induced by alloxan 150 mg/kg and given black pepper extract 122.5 mg/kg; treatment group 2 (P2), diabetic rats induced by alloxan 150 mg/kg and given black pepper extract 245 mg/kg; treatment group 3 (P3), diabetic rats induced by alloxan 150mg/kg and given sildenafil 1mg/kg. Libido’s measurement was done by observing intromission latency in second, mount latency in second, mount frequency by its quantity. Kruskal-Wallis test was used to analyzed introducing  latency, whereas mounting latency and mounting frequency was analyzed with One Way ANOVA.  The results showed that introducing latency of group P1 and P2 significantly different compared to group K2 (p=0,003, p=0,003), Mounting latency of group P1 significantly different compared to group K2 (p=0,000) and mounting frequency of group P1 and P2 significantly different compared to group K2 (p=0,000,p=0,006). Black pepper extract enhances male white rat (Rattus norvegicus) libido with diabetes mellitus.
Pendekatan Diagnostik Berbasis Manifestasi, Pemeriksaan Klinis dan Tatalaksana Pada Tuberkulosis Paru Juliana, Risna; Soleha, Tri Umiana; Yunianto, Andi Eka; Ismunandar, Helmi Ismunandar
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1347

Abstract

TB is a disease caused by MTB bacteria where this bacteria is able to attack the lung organs or extrapulmonary organs. The etiology of TB is caused through spit or phlegm from patients whose phlegm contains MTB bacteria. MTB bacteria have a rod shape and are acid-resistant, so they are known as acid-resistant bacteria (AFB). These bacteria do not have spores, so they will easily die if exposed to sunlight. However, this type of bacteria will be difficult to dye because it is acid-resistant, so a special staining method is needed, namely Ziehl Neelsen  staining. When a person coughs, water splashes will spread into the air and will then be inhaled by a healthy person, so the bacteria will enter the lungs and carry out the infection process. Usually, TB disease attacks at a productive age because at that age many people interact socially, making it easier for infectious infections to occur. . In general, the main symptoms are coughing up phlegm, which in some cases can mix with blood, chest pain, and shortness of breath . Confirmation of TB diagnosis can be done by conducting an anamnesis, physical examination, and supporting examination. TB treatment takes 6-12 months for patients who do not experience drug resistance. TB treatment consists of two stages, namely the initial stage and the advanced stage. The initial stage will last for two months, with the type of drug given is a combination of 2 HRZEs (Isoniazid, Rifampicin, Pirazinamid, and Etambutol). The advanced stage of treatment lasted for 4 months, with the drug given in the form of a combination of 4HR (isoniazid and rifampicin).
Krisis Hiperglikemik: Diabetic Ketoacidosis (DKA) dan Hyperglycemic Hyperosmolar State (HHS) Wibowo, Muhammad Rafi; Rudiyanto, Waluyo; Yunianto, Andi Eka; Soleha, Tri Umiana
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1435

Abstract

Hyperglycemic crisis is an acute metabolic complication of diabetes mellitus that can be life threatening if not treated appropriately. This research aims to examine in more depth the hyperglycemia crisis. This research is a literature study using relevant literature such as articles and journals from various national and international databases such as Google Scholar, NCBI, and PubMed. Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar State (HHS) are serious and emergency forms of hyperglycemic crisis. DKA is often found in people with type 1 diabetes due to severe insulin deficiency, which is characterized by the triad of hyperglycemia, acidosis, and ketosis. In contrast, HHS occurs more frequently in type 2 diabetes, with features of hyperglycemia, hyperosmolarity, and dehydration, but without significant ketosis and acidosis. Both of these conditions have a high risk of death if left untreated, with the death rate for DKA around <1% and HHS around 15%. The goal of treatment for both is to improve circulation and tissue perfusion, correct hyperglycemia, ketogenesis, and electrolyte imbalances, and identify precipitating factors. Treatment begins with correcting dehydration and electrolyte imbalances through rehydration with crystalloid fluids, as well as treating hyperglycemia by administering insulin boluses or infusions. Prevention of DKA and HHS is to ensure that patients do not stop insulin or oral hyperglycemic drugs, monitor blood sugar levels regularly and immediately seek professional medical help if something undesirable happens.
Merokok dan Vaping Sebagai Faktor Resiko Terjadinya Gangguan pada Hati Mubarak, Raka Anzil; Windarti, Indri; Yunianto, Andi Eka
Medula Vol 14 No 11 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i11.1463

Abstract

Conventional cigarettes and e-cigarettes (vaping) has a significant impact to health issues worldwide. There are more than 1.1 billion active smokers in the world and 8 million people die each year due to tobacco consumption. E-cigarette use is also increasing. The liver is responsible for metabolism and detoxification, so it is highly vulnerable to the toxic effects of chemical compounds from conventional cigarettes and e-cigarettes. This article is a literature study using secondary data from articles in national and international journals sourced from Google Scholar, NCBI, and PubMed. The purpose of this article is to review the relation between smoking, vaping, and the risk of liver disease, with a focus on the components of cigarettes and the mechanisms of liver damage. There are 4000 chemicals contained in cigarettes, including nicotine which are addictives and stimulants. The effects of smoking on the liver are caused by toxic, immunologic, and oncogenic mechanisms. The use of e-cigarettes or vaping is gaining popularity as a safe alternative to conventional cigarettes. However, each e-liquid solution can contain up to 60 chemicals that are harmful to the body. The effects of e-cigarettes on the liver are explained by complex mechanisms such as oxidative stress, inflammation, mitochondrial dysfunction and impaired lipid metabolism in the liver. Smoking affects the progression of liver diseases such as Hepatitis, Non Alcoholic Fatty Liver Diseases (NAFLD), Primary Billier Cholangitis (PBC), and Hepatocellular carcinoma (HCC). Vaping has an association with the incidence of NAFLD and HCC, but there is not yet strong enough evidence to associate it with the progression of Hepatitis and PBC.
Co-Authors Ahmad Faridi Ai Mahmudatusa’adah Aisyah, Iseu Siti Akbarini, Oon Fatonah Alam, Rafi Gustra Andy Muharry Ardhian, David Arfah Husna Arie Nugroho, Arie Arza, Putri Aulia Asep Rusyana Asep Suryana Abdurrahmat Astri, Desi Astriani, Aveny Septi Asyifa, Mega Atri Sri Ulandari Aviaty Dwina Aulia Ayu Lestari AYU LESTARI Betaditya, Dika Budi Setiawan Bustami Bustami Chandradewi, AASP. Daulay, Suryani A. Daulay, Suryani Agustina Dea Silvani Dian Isti Angraini DIan Siti Fatimah Diya Salsabila Dominikus Raditya Atmaka Dyah Raysa Laksitoresmi Eka Putri Rahmadhani Eliana Eliana Eliza - Sutarman Eliza Eliza Eliza Eliza Ellis Endang Nikmawati Elya, Elya Emy Yuliantini Emy Yuniantini Endang Sri Wahyuni Erna Susilowati Ernawaty, Tutik Fadly, Dzul Fajar Ningsih, Windi Indah Faridi, Ahmad Faridi, Ahmad Fertiasari, Rini Firdaus, Purna Hadibrata, Exsa Happy, Terza A Happy, Terza Aflika Hardiansyah, Angga Hasmar Fajrina Herdiansyah, Dadang Ike Anggraeni Ikeu Tanziha Ima Karimah Ima Saphira Indri Windarti Indriyani, Reni Irma Nuraeni Iseu Siti Aisyah Ismunandar, Helmi Ismunandar Isvari, Gusti Ayu Made Prathita Juliana, Risna Junita, Dini Kamsiah Kamsiah Kosnayani, Ai Sri Krisnasary, Arie Kristiandi, Kiki Larasati, Ratri M. Lasmono, Krisna Nurdin Lesi Oktiwanti Listyawardhani, Yana Lupiana, Mindo Lusina, Septia Eva M. Ridho Ulya Made Darawati Martianto, Djarat Masriani . Meiyanti Meiyanti, Meiyanti Miratul Haya miratul haya Miratul Haya Miratul Haya, Miratul Mubarak, Raka Anzil Muhammad Eka Asri Rizal Mulyani, Roza Muttalib, Yuges Saputri Nadia Chalida Nur Neni Neni Neni, Neni Ningsih, Windi Indah Fajar Noorlatifah Noorlatifah Nur, Zuhra Tun Nurlaili Nurlaili Nurtandhee, Mutiara Pardilawati, Citra Yuliyanda Pasambuna, Muksin Patrichia, Yolanda Pratiwi, Amali Rica Puji Laksmini Puspitasari, Ikha Deviyanthi Putri, Zakiah Meyra Rahmadi, Antun Ramadhana Komala Rauf Tamim Reni Zuraida Rian Diana Riduan, Alya Izzaty Rimbawan , Romdhona, Nur Rosyanne Kushargina Rosyanne Kushargina Roza Mulyani Rudiyanto, Waluyo Sanya Anda Lusiana Sari Khairinisa sherly sherly sherly sherly Siti Ratna Ningsih Sitti Syakira Sofyan Musyabiq Wijaya Soraya Rahmanisa Sri Anna Marliyati Sudarmi Sudarmi Suharmanto Sumarman Sumarman Sumarman Sumarman Suryana Suryana Suryana Suryana Suryana Suryana Susianti Sutrio Sutrio Sutrio Sutrio Sutrio Sutrio Taufiq Firdaus Al-Ghifari Atmadja Tetty Herta Doloksaribu tri antini Tri Antini, Tri Tri Umiana Soleha Ulinnuha, Najwa Usdeka Muliani Usdeka Muliani Utama, Lalu Juntra Vira Paujiah Nuriyah Walliyana Kusumaningati Wardani, Yusrima Syamsina Wibowo, Muhammad Rafi Widya Ayu Kurnia Putri Windi Indah Fajar Ningsih Wiwi Febriani Yana Listyawardhani Yana, Risda Yuges Saputri Muttalib Yulia Fitri Yuningrum, Hesti Zahra Tazkianisa Hadi Zuhra Tun Nur