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All Journal Jurnal Agronomi Indonesia (Indonesian Journal of Agronomy) Litera Jurnal Penelitian dan Pengembangan Pendidikan Indonesian Language Education and Literature Jurnal Penelitian Pendidikan IPA (JPPIPA) Pendas : Jurnah Ilmiah Pendidikan Dasar IRJE (Indonesian Research Journal in Education) Wahana : Tridarma Perguruan Tinggi Jurnal Pelita PAUD JUTEKS Jurnal Ilmiah Pendidikan dan Pembelajaran Jurnal Ilmu Hukum The Juris Jurnal Penelitian SELL (Scope of English Language Teaching, Linguistics, and Literature) Journal JuTEkS (Jurnal Teknik Elektro dan Sains) Edukasi Lingua Sastra Jurnal Teknologi Pendidikan : Jurnal Penelitian dan Pengembangan Pembelajaran Mosharafa: Jurnal Pendidikan Matematika Jurnal Farmasi Journal for Lesson and Learning Studies Britain International for Linguistics, Arts and Education Journal (BIoLAE Journal) Basic and Applied Nursing Research Journal Seminar Nasional Hasil Riset dan Pengabdian (SNHRP) Jurnal Pajak Vokasi (JUPASI) Abiwara : Jurnal Vokasi Administrasi Bisnis Formosa Journal of Multidisciplinary Research (FJMR) Buletin Kedokteran dan Kesehatan Prima SIENNA Terob : Jurnal Pengkajian dan Penciptaan Seni Duta Pharma Journal Jurnal Sejarah Islam Al-Irsyad Journal of Mathematics Education Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara JURNAL KESEHATAN YAMASI MAKASSAR Jurnal Smart Paud Ininnawa: Jurnal Pengabdian Masyarakat Southeast Asia Journal of Graduate of Islamic Business and Economics JEBD Jevief : Jurnal Vokasi Jurnal Kajian Islam dan Sosial Keagamaan Jurnal Pengabdian Masyarakat dan Riset Pendidikan Philosophiamundi : Journal of Global Humanistic Studies El-Mal: Jurnal Kajian Ekonomi & Bisnis Islam Jurnal Pengembangan Potensi Laboratorium Journal of Social Science Datuk Sulaiman Law Review (DaLRev) Jurnal Inovasi Pendidikan dan Pengajaran Journal of Ekonomics, Finance, and Management Studies JIKTIF Jurnal Riset Keperawatan dan Kesehatan Jurnal Pelita PAUD PAUDIA: JURNAL PENELITIAN DALAM BIDANG PENDIDIKAN ANAK USIA DINI Bionature Solidarity : Journal of Education, Social dan Culture Jurnal Teknik Sipil dan Perencanaan UPEJ : Unnes Physics Education Journal JHE (Journal of Health Education) Jurnal Pendidikan dan Sosial Humaniora Gayatri : Jurnal Pengabdian Seni dan Budaya
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Journal : Jurnal Farmasi

Optimasi Kapsul Bawang Putih (Allium sativum Linn) sebagai Terapi Alternatif Pengobatan TBC Yety Lindawati, Novena; Hartono
Jurnal Farmasi (Journal of Pharmacy) Vol. 2 No. 1 (2013): Jurnal Farmasi (Journal of Pharmacy), October 2013
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Garlic (Allium Sativum Linn) proven inhibiting the Mycobacterium tuberculosis propagation. Alisin compound which implied in garlic (Allium Sativum Linn) functioning as wide spectrum antimikroba capable to pursue Tuberkulosis cause by bacterium. Garlic Capsule (Allium Sativum Linn) have to fulfill conditions as according to Decree Of The Minister For Public Health of Republic Indonesia No: 661/MENKES/SK/VII/1994 about traditional medicines. The results shows that garlic extract with 240 µg/ml medium (equivalent by 600 mg garlic extract per capsule) has better potency in pursuing growth of Mycobacterium tuberculosis (taken a from pure breeding colony from patient sputum culture which suffering Tuberkulosis BTA type + 2, positive culture 9, resisten to rifampisin) compared to 320 and 400 µg / ml media.Dry extract of garlic (Allium Sativum Linn) fulfilling conditions upon which fill traditional drug capsule, for example total plate number 1.5 (qualifying at the most 10); mould and khamir number 6x102 (qualifying at the most 104); negative result of patogen bacteries such as coliform bacteries, Eschericia Coli, Salmonella Sp, and Staphylococcus aureus; negatife result of of aflatoxin (qualify at the most 30 bpj); total water content equal to 1 - 2 % (qualifying at the most 10 %). Dry garlic extract (Allium Sativum Linn) capsule fulfilling conditions of pharmaceutical form of traditional capsule result disintegration time less than 13 minute (qualify at the most 15 minute) and fulfill uniformity of weight which qualify for the traditional capsule
Potensi Anti Hiperkolesterolemia Ekstrak Tumbuhan Sarang Semut (Myrmecodia Pendans Merr. & Perry) Hartono; Setiawan, Iwan; Saktiningsih, Hari
Jurnal Farmasi (Journal of Pharmacy) Vol. 3 No. 1 (2014): Jurnal Farmasi (Journal of Pharmacy), October 2014
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Hiperkolesterolemia adalah salah satu gangguan kadar lemak dalam darah (dislipidemia) yang mana kadar kolesterol dalam darah lebih dari 240 mg/dl. Hiperkolesterolemia merupakan salah satu faktor risiko penyebab terjadinya penyakit jantung koroner yang merupakan penyebab utama dan pertama dari seluruh kematian. Kandungan flavonoid Tumbuhan Sarang Semut (Myrmecodia pendens Merr. & Perry) memiliki potensi sebagai obat antihiperkolesterolemia, karena dapat menurunkan kolesterol total, Low Density Lipoprotein (LDL), dan dapat mencegah oksidasi LDL. Tujuan penelitian ini mempelajari potensi ekstrak tumbuhan sarang semut dalam menurunkan kadar kolesterol dan kadar Low Density Lipoprotein (LDL), serta kadar trigliserida serta peningkatan kadar HDL. Penelitian dilakukan dengan rancangan penelitian Pre and Post Randomized Controlled Group Design menggunakan binatang coba tikus putih (Rattus norvegicus) jantan, strain Wistar, dengan kriteria inklusi yaitu sehat dan mempunyai aktivitas normal, berumur kira-kira 12 -16 minggu dengan berat badan ± 200 gram sebagai objek penelitian. Penelitian dilakukan dengan 6 kelompok tikus yaitu kelompok normal, kontrol negatif, kontrol positif dan 3 perlakukan dengan mempergunakan pemberian ekstrak sarang semut dengan dosis 400 mg/KgBB, 600 mg/KbBB dan 800 mg/KgBB. Analisa data kadar kolesterol total, trigliserid, HDL dan Low Density Lipoprotein (LDL) menggunakan one way ANOVA α=0,05 dengan uji lanjutan uji Tukey. Hasil penelitian menunjukkan bahwa secara kualitatif ekstrak tumbuhan sarang semut positif menunjukkan adanya senyawa flavonoid. Ekstrak tumbuhan sarang semut memiliki potensi sebagai antihiperkolesterolemia untuk menurunkan kadar kolesterol total dan menaikkan kadar kolesterol HDL secara bermakna pada dosis 800 mg/KgBB. Uji one way ANOVA, ekstrak tumbuhan sarng semut memiliki probabilitas 0,004 lebih kecil daripada 0,05. Uji t test menunjukkan bahwa probabilitas 0,0046 < 0,025. Ekstrak tumbuhan sarang semut juga dapat menurunkan kadar trigliserid dan kolesterol LDL pada hewan uji namun tidak berbeda bermakna. Kesimpulan dari penelitian ini adalah ekstrak tumbuhan sarang semut memiliki potensi sebagai obat antihiperkolesterolemia menurunkan kadar kolesterol total dan meningkatkan kadar kolesterol HDL.
Formulasi dan Evaluasi Tablet Floating furosemida Gastroretentif Menggunakan Kitosan Dari Cangkang Keong Mas (Pomacea canaliculata) Setiawan, Iwan; Hartono
Jurnal Farmasi (Journal of Pharmacy) Vol. 4 No. 1 (2015): Jurnal Farmasi (Journal of Pharmacy), October 2015
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Chitosan is kind of a natural polymer which is a product of deacetylation of chitin which can be obtained from the shells of golden snails (Pomacea canaliculata). Gastroretentive drug delivery systems can help improve the bioavailability, can maintain contact time of the drug longer with the gastrointestinal mucosa cause bioavailability of the drug will be higher, the efficacy of therapy, reducing the time interval of drug administration, reduce therapeutic doses and will ultimately improve patient compliance. The objective of the present study was to develop and evaluate gastroretentive floating tablet of furosemida using chitosan of shell golden snails. Chitosan which is isolated from the shells of snails formulated as polymer concentration variation in the formula of making floating tablets furosemide. The results showed shells of snails obtained from chitosan yield of 10.8%. Furosemide tablets containing chitosan polymers produce good powder and meets the requirements include the flow time, angle of repose and compressibility index, uniformity of weight, hardness, friability and disintegration time. The Formulation F3 containing (Furosemide with the highest concentration of chitosan) was found to the best. The test results mainly floating tablet hardness and Buoyancy / floating test showed significantly different results with furosemide tablets containing no polymer chitosan. This suggests that the natural polymer chitosan derived from the shells of golden snails are potentially as the building blocks of making tablets with gastroretentive drug delivery systems.
Tingkat Kepatuhan Penggunaan Ramuan Jamu Saintifik Hiperglikemia pada Pasien Diabetes Melitus di Rumah Riset Jamu Hortus Medicus B2P2TOOT Tawangmangu Hartono; Ary Kusumastuti, Livia
Jurnal Farmasi (Journal of Pharmacy) Vol. 8 No. 1 (2019): Jurnal Farmasi (Journal of Pharmacy), October 2019
Publisher : Jurnal Farmasi (Journal of Pharmacy)

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Abstract

Diabetes mellitus is a degenerative disease caused by chronic metabolic disorders characterized by high blood sugar. The levels compliance with treatment therapy can improve the success of therapy. This research purpose to determine the level of patient compliance level of use of scientific herbal medicine hyperglycemia in diabetes mellitus in Hortus Medicus Herbal Medicine Research House B2P2TOOT Tawangmangu. This research is a descriptive research, using data collection namely purposive sampling. The instruments used for compliance testing using MMAS-8 questionnaire. Data studied inclued age, gender, type of medicine, education, occupation, duration of suffering, and level of patient compliance as well as factors related to compliance. Results research on 96 respondents showed that including the category levels of patient adherence to the use of scientific herbal medicine hyperglycemia was high 48%, moderate adherence rate of 43% and low adherence level of 9%. Based on the results of the study it can be concluded that compliance level of use of scientific herbal medicine hyperglycemia in diabetes mellitus in Hortus Medicus Herbal Medicine Research House B2P2TOOT Tawangmangu classified as high category 48%.
KAJIAN ETNOFARMASI PENGGUNAAN TUMBUHAN OBAT SEBAGAI ALTERNATIF PENGOBATAN DIARE OLEH MASYARAKAT SUKU OSING DUSUN KRAJAN Septa, Amira; Hartono; Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 1 (2023): Jurnal Farmasi (Journal of Pharmacy), April 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/rn63em44

Abstract

Diarrhea is a disease that is still a health problem worldwide, including Indonesia. Diarrhea is included in the top 10 diseases that still occur frequently and is ranked 5th in the Osing Tribe. The Osing tribe community treats diarrhea by utilizing plants as medicinal plants that are used from generation to generation. This study was conducted to determine the use of ethnopharmaceuticals in the Osing tribe as a preliminary study for the development of traditional medicine by the Osing tribe as a standardized herbal medicine or phytopharmaca. This research is a descriptive study using qualitative methods with snowball sampling techniques through open- ended interviews with filling out informant information sheets and involving 22 community informants from the Osing tribe, Krajan Hamlet, Kemiren, Glagah, Banyuwangi, East Java. The results of ethnopharmaceutical research in the Osing tribe showed that there were 8 types of plants used for the treatment of diarrhea. Analysis using ICF (Informant Consensus Factor) with a result of 0.6 means that the plant is trusted and used as a hereditary treatment of diarrhea treatment. In the PPV (Plant Part Value) value analysis, which is to calculate the part of the plant used, the results obtained were 50% of the leaves, 23% of the fruit, 27% of the rhizome. Fidelity Level (FL) to determine the type of plant that is most often used in treating diarrhea with the highest result of 100% from among others Guava (Psidium guajava L.) and Cassava (Manihot esculenta).
EVALUASI PENYIMPANAN OBAT DI APOTEK INDRA SUKOHARJO Dwi H, Aminah; Hartono
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 2 (2023): Jurnal Farmasi (Journal of Pharmacy), October 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/rk5yvz94

Abstract

Regulation of the Minister of Health of the Republic of Indonesia No. 73 of 2016 concerning Pharmacy Pharmaceutical Service Standards states that pharmacies are a means of pharmaceutical services where pharmaceutical practices are carried out by Pharmacists. Pharmaceutical service standards that aim to improve the quality of pharmaceutical services, security, storage and distribution or distribution of drugs, services on prescriptions or not with prescriptions, drug information services, guarantee legal certainty for pharmaceutical personnel, and protect patients and the public from irrational use of drugs in the context of patient safety. Good drug storage will ensure the quality of drug preparations, avoid irresponsible use of drugs, maintain the availability and service of pharmaceuticals and facilitate the search and supervision. Evaluation of good drug storage should be carried out by all pharmaceutical services including pharmacies. This study aims to evaluate drug storage in Indra pharmacies based on the physical condition of drug storage shelves and warehouses, how to store drugs, record stock cards, and safeguard drug quality. This research is a type of observational research by observing objects and the results are presented descriptively, and data collection is carried out by documentation and interviews at the Pharmacist in Charge of Apotek Indra Sukoharjo. The results of the evaluation of drug storage at Indra Sukoharjo Pharmacy as many as 77.8% have met the standards in accordance with the Regulation of the Minister of Health Number 73 of 2016 concerning Pharmaceutical Service Standards in Pharmacies. The results of the evaluation of the condition of the rooms and facilities in the drug storage warehouse of Apotek Indra Sukoharjo based on the Technical Guidelines for Good Drug Distribution Methods set by the Food and Drug Control Agency in 2020 were 54.2% who had met the standards and 45.8% had not met the standards.
Hubungan Antara Tingkat Pengetahuan dengan Tingkat Kepatuhan Penggunaan Obat Antihipertensi di Instalasi Rawat Jalan RS UNS: Jurnal Farmasi (Journal of Pharmacy), October 2025 Ekawati, Oktavia; Hartono; Dian Anggraini, Truly
Jurnal Farmasi (Journal of Pharmacy) Vol. 14 No. 2 (2025): Jurnal Farmasi (Journal of Pharmacy), October 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/m9kx3655

Abstract

Hypertension is still the largest disease in Central Java Province in the first quarter of 2023 at 63%. Various efforts to reduce mortality and morbidity due to hypertension have been carried out on a massive scale. The success of treating hypertension is influenced by a number of factors. An example of factors that have an impact is the patient's level of knowledge and understanding of hypertension and patient compliance in undergoing treatment. Knowledge and understanding are very necessary for patients to understand what to do and avoid so that treatment is successful. Compliance with hypertension treatment is important to monitor blood pressure and avoid complications. The research was conducted with the aim of determining the relationship between the level of knowledge and compliance with the use of antihypertensive drugs at UNS Sukoharjo Hospital. The study carried out was a cross-sectional type of research using a questionnaire. Compliance was measured using ARMS (Adherence to Refills and Medication Scale). The sampling technique used is purposive sampling which has inclusion provisions: patients who seek treatment in January-March 2024, undergo routine examinations. The number of samples that met the inclusion and exclusion requirements was 178 patients. Data analysis carried out the Spearman rank correlation test. The study findings show that patients who have a poor level of knowledge about hypertension and its treatment are 4.5%, a sufficient level of understanding is 28.1% and a good level of understanding is 67.4%. The level of patient compliance in using antihypertensive drugs in the low category was 62.4% and in the high category was 37.6%. The results of the Spearman rank correlation test obtained a p value of 0.000 (<0.05) which has a correlation value of 0.262. This indicates that there is a relationship with weak correlation strength on the level of knowledge and compliance in using antihypertensive drugs in the outpatient installation of UNS Sukoharjo Hospital.
Co-Authors A. Harijono A.Irma Suryani A.Muflihunna Abdillah Arif Nasution Achmad Fahruddin Adiningsih, Retnowati Ahmad Nur Akhmad Ravi Eka Baharsyah Al-Amin, Yusuf Amalia, Lidya Andi Rahmat Saleh Anisa Antika, Dewi Hajar Windi Anwar Efendi Aprilia, Rida Ari Kusmiatun Ariyanto Nugroho arsana, i wayan Ary Kusumastuti, Livia Azhari, Mohammad Chusnul Belinda Dewi Regina Brotosejati, Widodo Burhan Nurgiyantoro Chitra Sintarani Danang Prasetyo, Danang Danu Rusmawati, Retno Darlis Darlis, Darlis Darmaningrum , Chicilia Puspita Darmilus DENI SETIAWAN Dewi Ratnaningsih Dewi, Dina Omayani Dhina Cahya Rohim Dhita Nur Fitriana Dian Anggraini, Truly Diana Diana Anggraini Kusumawati Dwi Budiyanto Dwi Fitriyani, Dwi Dwi H, Aminah Dwi Oktaviana Dwihandoko, Toto Heru Dyah Ayu Anggraini Ekawati, Oktavia Eko Raharjo Else Liliani Elwita Nafa Fitria Emaus Zulkarnain, Albert Erwis Evi Kurniasari Evi Marpiah Fadhilah, Ayu Faisal Fajar Farida Nursyahidah Fathur Rokhman Fathur Rokhman Finawati, Ari Fitriana, Lala Budi Fitriani Fitriani, Devi Asfira Fransiskus Chrystiano Totty Satria Nugraha Ginting, Gita Br Gusti Ayu Made Puspawati Hala, Yusmina Hamka L. Handayani, Ita Kris Hardiyani, Ita Kris Harnanto Hartati Haryanto, Wawan Hasyimy, Muhammad Afaf Hendrik Feniber HEVY DWI PRATIWI Hilda Karim Hugo Prasetyo Winotoatmojo I Ketut Lanus Indraswari Islamiyah, Ummi Habibatul Iwan Setiawan Juhan Syah, Fahmi Junaedy Khaeriyah, Denti Zaedatul Komang David Darmawan, David Kristina, Marilin Kumagaya, Yohannnes P Kushariyadi Lobertus Sivi Made Susilawati Maharani, Okvi Malarsih Mega Arisia Dewi Moesyarofah Mohammad Muslimin Mohammad Muslimin Mudhar, Mudhar Muhamad Risal Tawil Muhammad Dzaki Jhon Ramadhan Muhammad Firdaus Muhammad Iqbal Ripo Putra Mukhtar Munisa, A. Munisa Muwakhidah, Muwakhidah Nandang Lukmanul Basar Naomi Diah Budi Setyaningrum, Naomi Diah Budi Nersiwad Ningtias, Akgis Cahya Ninik Rahayu Nugrahanny, Ageng Nuniek Yuniarti Ningsih Renggaala Nur Alamsyah, Nur Nurkolis Nurkolis Oslan Jumadi Pane, Putri Yunita Pramudya, Rorry Pratama, Kharisma Pujiharta Purwaka Hari Prihanto Rafli Maulana Heryadi Rahmat, Laodemuh Ratnasari, Fifin Dewi Renika Hasibuan Rina Nurjanah Riyanti Robby Hidajat Rusdianto Rusmawati, Retno Danu Sabjan Badio Saktiningsih, Hari Sandie Santari, Putri Tria Santy Deasy Siregar Saragih, Meysi Dea Vinata R. Sari, Dina Lita Sari, Rinda Septa, Amira Setiawan, M. Budhi Simangungsong, Pahala Maringan Jubel Siswanto, Chika Putri Siti Muawanah Robial Siti Munfiatik Sitorus, Angel Juliana Peace Sitti Saenab Sonianto Sonianto Sri Mulyani Sri Sumarni Sri Wahyuni Sri Wulandari St. Fatma Hiola Subawi, Handoko Sucipto Hadi Purnomo Suharto Linuwih Sukarman, Lufi Afita Kardina Sukismanto, Sukismanto Sukniasih Sumardiyono Suprianus Pian T.A Surahman Nur Surbakti, Yemima Valentin Br Suroso Suroso Syarifuddin Syarifuddin Tedy Setiadi Tri Rejeki Andayani Tri Wahyuningtyas, Tri Ulfa Jamilatul Farida Utin Desy Susiaty Vera Selviana Adoe Victor Yudistira Antoro Wagiran Wagiran Wapuah Widyawati, Yekti Wulan Citra Sari Yadi Ardiawan Yanti Yesdia Talakua Yety Lindawati, Novena Yuli Utanto Yuliasnita Verlandes Yuliawati, Ernita Yusuf Yenni Zulkifli