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Yunianto, Andi Eka
Universitas Lampung
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Journal : Journal of Dietetics Science

 1 
Hubungan Kadar Asam Urat dengan Kadar Kolesterol HDL pada Peserta Prolanis di Puskesmas Kedaton Bandar Lampung Eka Yunianto, Andi; Sutrio
Journal of Dietetics Science Vol. 1 No. 2 (2025): Journal of Dietetics Science
Publisher : Nutrition Department, Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jds.v1i2.5367

Abstract

ABSTRACT Uric acid and High-Density Lipoprotein (HDL) are important biomarkers associated with the risk of metabolic and cardiovascular diseases. Hyperuricemia is known to increase the risk of hypertension, metabolic syndrome, and heart disease, while low HDL levels contribute to atherosclerosis. However, the relationship between uric acid and HDL levels is still not entirely consistent in various studies. This study aims to analyze the relationship between uric acid and HDL levels in Prolanis patients at the Kedaton Community Health Center, Bandar Lampung. The study used a cross-sectional design involving 42 respondents aged 42–76 years. Data were collected through venous blood examination of 8 ml. HDL levels were measured using the Chod-Pap method, while uric acid levels were measured using the Uricase method. Data analysis used the Pearson test with a significance level of p <0.05. Based on the average HDL level of respondents was 49.79 ± 7.67 mg/dl, while uric acid levels were 7.17 ± 8.13 mg/dl. Correlation analysis showed a significant positive relationship between uric acid levels and HDL (r=0.339; p=0.028). There was a positive relationship between uric acid levels and HDL, indicating that uric acid, at certain levels, may act as an antioxidant that supports lipid metabolism. However, high uric acid levels remain a risk factor for metabolic disease. Further research with larger samples is needed to confirm these findings. ABSTRAK Asam urat dan High-Density Lipoprotein (HDL) merupakan biomarker penting yang berhubungan dengan risiko penyakit metabolik dan kardiovaskular. hiperurisemia diketahui meningkatkan risiko hipertensi, sindrom metabolik, dan penyakit jantung, sementara kadar hdl rendah berkontribusi pada aterosklerosis. namun, hubungan antara kadar asam urat dan HDL masih belum sepenuhnya konsisten dalam berbagai studi. Penelitian ini bertujuan untuk menganalisis hubungan antara kadar asam urat dan kadar HDL pada pasien prolanis di puskesmas kedaton, bandar lampung. Penelitian menggunakan desain potong lintang dengan melibatkan 42 responden berusia 42–76 tahun. data dikumpulkan melalui pemeriksaan darah vena sebanyak 8 ml. kadar hdl diukur dengan metode chod-pap, sedangkan kadar asam urat dengan metode uricase. analisis data menggunakan uji pearson dengan tingkat signifikansi p<0,05. Berdasarkan rata-rata kadar HDL responden adalah 49,79 ± 7,67 mg/dl, sedangkan kadar asam urat 7,17 ± 8,13 mg/dl. analisis korelasi menunjukkan adanya hubungan positif signifikan antara kadar asam urat dan hdl (r=0,339; p=0,028). Terdapat hubungan positif antara kadar asam urat dan HDL, yang mengindikasikan bahwa asam urat pada kadar tertentu mungkin berperan sebagai antioksidan yang mendukung metabolisme lipid. namun, kadar asam urat yang tinggi tetap berisiko terhadap penyakit metabolik. penelitian lanjutan dengan sampel lebih besar diperlukan untuk mengonfirmasi temuan ini.
Co-Authors Ahmad Faridi Ai Mahmudatusa’adah Aisyah, Iseu Siti Akbarini, Oon Fatonah Andy Muharry Angga Hardiansyah Ardhian, David Arfah Husna Arie Nugroho, Arie Arza, Putri Aulia Asep Rusyana Asep Suryana Abdurrahmat Astri, Desi Astriani, Aveny Septi Asyifa, Mega Atri Sri Ulandari Aviaty Dwina Aulia Ayu Lestari AYU LESTARI Betaditya, Dika Budi Setiawan Bustami Bustami Chandradewi, AASP. Daulay, Suryani A. Daulay, Suryani Agustina Dea Silvani Dian Isti Angraini DIan Siti Fatimah Diya Salsabila Dominikus Raditya Atmaka Dyah Raysa Laksitoresmi Eka Putri Rahmadhani Eliana Eliana Eliza - Sutarman Eliza Eliza Eliza Eliza Ellis Endang Nikmawati Elya, Elya Emy Yuliantini Emy Yuniantini Endang Sri Wahyuni Erna Susilowati Fadly, Dzul Fajar Ningsih, Windi Indah Faridi, Ahmad Faridi, Ahmad Fertiasari, Rini Firdaus, Purna Hadibrata, Exsa Happy, Terza A Happy, Terza Aflika Hasmar Fajrina Herdiansyah, Dadang Ike Anggraeni Ikeu Tanziha Ima Karimah Ima Saphira Indri Windarti Indriyani, Reni Irma Nuraeni Iseu Siti Aisyah Ismunandar, Helmi Ismunandar Isvari, Gusti Ayu Made Prathita Juliana, Risna Junita, Dini Kamsiah Kamsiah Kosnayani, Ai Sri Krisnasary, Arie Kristiandi, Kiki Larasati, Ratri M. Lasmono, Krisna Nurdin Lesi Oktiwanti Listyawardhani, Yana Lupiana, Mindo Lusina, Septia Eva Made Darawati Martianto, Djarat Masriani . Miratul Haya Miratul Haya miratul haya Miratul Haya, Miratul Mubarak, Raka Anzil Muhammad Eka Asri Rizal Mulyani, Roza Muttalib, Yuges Saputri Nadia Chalida Nur Neni Neni Neni, Neni Ningsih, Windi Indah Fajar Noorlatifah Noorlatifah Nur, Zuhra Tun Nurtandhee, Mutiara Pasambuna, Muksin Patrichia, Yolanda Pratiwi, Amali Rica Puji Laksmini Puspitasari, Ikha Deviyanthi Rafi Gustra Alam Rahmadi, Antun Ramadhana Komala Rauf Tamim Reni Zuraida Rian Diana Riduan, Alya Izzaty Rimbawan , Romdhona, Nur Rosyanne Kushargina Rosyanne Kushargina Roza Mulyani Rudiyanto, Waluyo Sanya Anda Lusiana Sari Khairinisa sherly sherly sherly sherly Siti Ratna Ningsih Sitti Syakira Sofyan Musyabiq Wijaya Soraya Rahmanisa Sri Anna Marliyati Sudarmi Sudarmi Suharmanto Sumarman Sumarman Sumarman Sumarman Suryana Suryana Suryana Suryana Suryana Suryana Susianti Sutrio Sutrio Sutrio Sutrio Sutrio Sutrio Taufiq Firdaus Al-Ghifari Atmadja Tetty Herta Doloksaribu tri antini Tri Antini, Tri Tri Umiana Soleha Ulinnuha, Najwa Ulya, M. Ridho Usdeka Muliani Usdeka Muliani Utama, Lalu Juntra Vira Paujiah Nuriyah Walliyana Kusumaningati Wardani, Yusrima Syamsina Wibowo, Muhammad Rafi Widya Ayu Kurnia Putri Windi Indah Fajar Ningsih Wiwi Febriani Yana Listyawardhani Yuges Saputri Muttalib Yulia Fitri Yuningrum, Hesti Zahra Tazkianisa Hadi Zuhra Tun Nur