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All Journal Media Kedokteran Hewan Jurnal Ternak Tropika Biomedical Journal of Indonesia Jurnal Medik Veteriner ARSHI Veterinary Letters Journal of Applied Veterinary Science and Technology Bioscientist : Jurnal Ilmiah Biologi Jurnal Kedokteran Hewan Borneo Journal of Pharmacy Journal of Agro Complex Development Society
Khairullah, Aswin Rafif
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Immunology & microbiology Medicine & Pharmacology Social Sciences Veterinary

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A Comparative Study Between E-Cigarette Vapor and Cigarette Smoke Exposure on the Lungs of Mice (Mus musculus) Putri, Mirtanti Kiswandi; Hestianah, Eka Pramyrtha; Kuncorojakti, Suryo; Widiyatno, Thomas Valentinus; Sukmanadi, Mohammad; Santoso, Kuncoro Puguh; Plumeriastuti, Hani; Hidayatik, Nanik; Khairullah, Aswin Rafif
Journal of Applied Veterinary Science And Technology Vol. 6 No. 2 (2025): October 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/javest.V6.I2.2025.102-108

Abstract

Background: Cigarettes are tobacco products processed with or without additives and are known to contain addictive substances that pose serious health risks to individuals and the public. Inhaled cigarette smoke directly stimulates the activation of macrophage cells in the respiratory tract. Among the affected cells, type II alveolar cells which produce pulmonary surfactant to reduce alveolar surface tension are particularly vulnerable to smoke-induced damage. Purpose:  This study aimed to compare the effects of conventional cigarette smoke and e-cigarette vapor exposure on the number of alveolar macrophages and type II alveolar cells in male mice (Mus musculus). Method: A total of 28 male mice were randomly divided into seven groups. The control group (C) was exposed to ambient air only. Groups A1, A2, and A3 were exposed to 1, 2, and 3 conventional cigarettes per day, respectively, while groups B1, B2, and B3 were exposed to 0.7 mL, 1.3 mL, and 2 mL of e-liquid vapor per day, respectively. All exposures were conducted for 36 consecutive days. Results: A significant difference (p<0.05) was observed in the number of alveolar macrophages among groups C, A1, A2 , A3 , B2 , and B3 , whereas no significant difference was found between A1 and B1. The number of type II alveolar cells significantly differed (p < 0.05) across all groups: C, A1, A2, A3, B1, B2, and B3. Conclusion: Both conventional cigarette smoke and e-cigarette vapor increase alveolar macrophage counts and reduce type II alveolar cell numbers compared to controls. Although both exposures pose health risks, e-cigarette vapor appears to cause milder pulmonary effects than conventional cigarette smoke.
Kualitas Susu Sapi Segar di Peternakan Sapi Perah Kota Batu Dameanti, Fidi Nur Aini; Amri, Indah Amalia; Kurniawati, Siti; Adrenalin, Sruti Listra; Erlinda, Tira; Masardhi, Bagus Aji; Dion, Nadia Ananda Prasetia; Nirmalasari, Na Young; Izofani, Safira; Yanestria, Sheila Marty; Khairullah, Aswin Rafif
TERNAK TROPIKA Journal of Tropical Animal Production Vol. 26 No. 2 (2025): TERNAK TROPIKA Journal of Tropical Animal Production
Publisher : Jurusan Produksi Ternak, Fakultas Peternakan, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtapro.2025.026.02.3

Abstract

Peningkatan permintaan susu nasional setiap tahunnya menunjukkan konsumsi susu nasional meningkat sehingga diperlukan upaya dalam peningkatan produksi susu melalui peningkatan kesehatan sapi perah yang dapat meningkatkan kualitas maupun kuantitas susu. Faktor genetik, kesehatan, lingkungan, dan manajemen pakan perlu diperhatikan dalam pemeliharaan sapi perah. Penelitian dilakukan dengan 58 sampel susu dari peternak di Kota Batu dengan tujuan melakukan evaluasi kualitas susu sapi di Kota Batu. Analisis kualitas susu dilakukan menggunakan lactoscan untuk menilai kadar lemak, bahan kering tanpa lemak, berat jenis, laktosa, mineral, protein, penambahan air, suhu, dan titik beku pada susu. Hasil analisis data dilakukan secara deskriptif. Hasil uji pada lacoscan terdapat 75,86% tidak sesuai SNI 3141: 2011 pada parameter density, 77,58% pada freeze point, 43,10% pada protein, 41,37% pada temperature, 27,58% pada add water, 15,51% pada lemak, 13,79% pada lactose, dan 3,44% pada solid non fat. Berdasarkan hasil uji perlu dilakukan evaluasi dalam manajemen pemeliharaan ternak.
Detection of the iroN gene in strains of avian pathogenic Escherichia coli in ducks at the Surabaya live market Kendek, Irfan Alias; Effendi, Mustofa Helmi; Wibisono, Freshinta Jellia; Putri, Mariana Febrilianti Resilinda; Abidin, Zainul; Naseh, Naseh; Rehman, Saifur; Khairullah, Aswin Rafif; Yanestria, Sheila Marty; Pratama, Bima Putra; Kurniasih, Dea Anita Ariani; Ahmad, Riza Zainuddin; Tang, John Yew Huat; Kurniawan, Muhammad ‘Ahdi; Dameanti, Fidi Nur Aini Eka Puji
Jurnal Medik Veteriner Vol. 9 No. 1 (2026): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol9.iss1.2026.242-258

Abstract

Escherichia coli normally inhabits the intestinal tract of poultry as a commensal organism; however, specific strains such as avian pathogenic E. coli (APEC) may become opportunistic pathogens responsible for colibacillosis in birds. The inappropriate use of antibiotics can increase antimicrobial resistance, which may impact public health. This study aimed to detect the presence of the iroN virulence gene specifically in multidrug-resistant (MDR) E. coli isolates associated with APEC obtained from duck cloacal swabs collected at live markets in Surabaya. This study was designed as a descriptive cross-sectional survey, and the results are presented as prevalence proportions without inferential or correlation statistical testing, as iroN detection was performed exclusively on MDR isolates. Samples were collected from five live markets in Surabaya and cultured on MacConkey agar (MCA). E. coli was identified morphologically through Gram staining and biochemically using Triple Sugar Iron Agar (TSIA), Sulfide Indole Motility (SIM), Simmons Citrate Agar (SCA), indole, and methyl red–Voges–Proskauer (MR–VP) tests. Antimicrobial susceptibility testing was performed on all confirmed E. coli isolates (n = 120), and PCR analysis of the iroN gene was subsequently conducted only on MDR isolates (n = 14). The identification rate of E. coli in this study was 83.3% (120/144). Resistance to erythromycin was 81.7% (98/120), which likely reflects the intrinsic resistance of Gram-negative bacteria to macrolides rather than acquired antimicrobial resistance. This was followed by resistance to gentamicin at 19.2% (23/120), ciprofloxacin at 14.2% (17/120), aztreonam at 3.3% (4/120), and chloramphenicol at 2.5% (3/120). The prevalence of multidrug resistance (MDR) was 11.6% (14/120). Among these MDR isolates, 42.8% (6/14) were positive for the iroN virulence gene. No statistical association between MDR status and iroN carriage was assessed because non-MDR isolates were not screened for iroN. These findings provide baseline descriptive data on MDR and iroN-positive E. coli in traditional markets in Surabaya based on a limited panel of representative antimicrobial classes, without inferring specific resistance mechanisms such as extended-spectrum β-lactamase (ESBL) production.
Co-Authors . Kholik Abuzahra, Mutasem Adi Sofyan Ansori, Muhammad Adrenalin, Sruti Listra Afnani, Daniah Ashri Agung Prasetyo Aini, Nur Sofiatul Akintunde, Adeyinka Oye Aksono HP., Eduardus Bimo Al arif, Mohammad Anam Al Baariq, Hisyam Nabil Najmuddin Ali Agus Amri, Indah Amalia Amrullah, Muhammad Fajar Ardhanella, Sellianova Aryaloka, Suhita Ayuti, Siti Rani Azis, Nurul Magfirah Bezhinar, Tatyana Brahmantya, Chandra Burkov, Pavel Chandramohan, Koshini Chusniati, Sri Dameanti, Fidi Nur Aini Eka Puji Derkho, Marina Dion, Nadia Ananda Prasetia Eka Pramyrtha Hestianah, Eka Pramyrtha Endang Suprihati Erlinda, Tira Erma Safitri Erna Yuniati Fadlilah, Shinta Levea Ni'matul Fauzia, Kartika Afrida Fauziah, Ima Fedik Abdul Rantam Fitrine Ekawasti, Fitrine Gudz, Petr Guselsa, Fricelia Aura Hani Plumeriastuti Harijani, Nenny Hasib, Abdullah Herdiansyah, Mochammad Aqilah Herry Agoes Hermadi Hery Purnobasuki Hidanah, Sri Hidayatik, Nanik I wayan Teguh Wibawan Ikhsan, Dilla Amalia Bilqis Ilmi, Laily 'Ulya Nurul IMAM MUSTOFA Ira Sari Yudaniayanti Izofani, Safira Kadek Rachmawati Karina, Soca Karjono Karmanis Kendek, Irfan Alias Khairunnisa, Rahma Kharisma, Viol Dhea Kinasih, Kurnia Nisa Kuncorojakti, Suryo Kurniasih, Dea Anita Ariani Kurniawan, Muhammad 'Ahdi Kurniawan, Muhammad ‘Ahdi Kurniawan, Shendy Canadya Kusala, Muhammad Khaliim Jati Kusnoto Kusnoto, Kusnoto Kusumawati, Evyana Diah Lucia Tri Suwanti, Lucia Tri Ma'ruf, Anwar Maksimiuk, Nikolai Masardhi, Bagus Aji Mirni Lamid Moses, Ikechukwu Benjamin Mufasirin Munawir Sazali Murtadlo, Ahmad Affan Ali Mustika, Yolla Rona Mustofa Helmi Effendi Naseh, Naseh Nayan, Nazri Nirmalasari, Na Young Nur Rusdiana Nurliyani Nurliyani Pamungkas, Fajrin Yudha Panggabean, Rosenna Tiara Pasang, Gabriel Sampe Poedji Hastutiek Pratama, Bima Putra Puarada, Alif Rahman Rohim Purba, Hastuti Handayani S. Putra, Oktavian Arya Putri, Mariana Febrilianti Resilinda Putri, Mirtanti Kiswandi Putri, Natalie Lovena Pramono Raharjo, Dadik Rahmahani, Jola Rahmawati, Septyana Eka Raissa, Ricadonna Ramadhan, Nuzula Rijal Nur Ramandinianto, Sancaka Chasyer Ratna Damayanti Rebezov, Maksim Rehman, Saifur Rimayanti Rimayanti Rimayanti Riska Riska Riwu, Katty Hendriana Priscilia Riza Zainuddin Ahmad Rochmah Kurnijasanti Rollando, Rollando Rosyada, Zulfi Nur Amrina Sabdoningrum, Emy Koestanti Safika S, Safika Santoso, Kuncoro Puguh Sapta Andaruisworo Sari, Aulia Puspita Setiawan Koesdarto Sheila Marty Yanestria Siti Kurniawati Sri Mulyati Sri Suryatmiati Prihandani Suherni Susilowati Sukmanadi, Mohammad Supriyadi Supriyadi Susan Maphilindawati Noor Suwarno Suwarno Suzanita Utama Tang, John Yew Huat Tanjungsari, Ardina Teguh Hari Sucipto, Teguh Hari Tika Hafzara Siregar Tita Damayanti Lestari Tyasningsih, Wiwiek Ulhaq, Oktania Dhiya Wahyuningtias , Dita Sheila Putri Wardhani, Bantari Wisynu Kusuma Warsito, Sunaryo Hadi Wibisono, Freshinta Jellia Wibowo, Syahputra Widiyatno, Thomas Valentinus Widya Paramita Lokapirnasari Widyananda, Muhammad Hermawan Yulianna Puspitasari Yunus, Muchammad Zainul Abidin