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All Journal Jurnal Gizi dan Pangan Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Ilmu Lingkungan Jurnal Natur Indonesia Jurnal Kedokteran Brawijaya Jurnal Ilmu Perairan (Aquatic Science) Medical Journal of Indonesia Jurnal Bioterdidik: Wahana Ekspresi Ilmiah Jurnal Pembangunan dan Alam Lestari Indonesian Journal of Human Nutrition Jurnal Sains dan Teknologi Farmasi Majalah Kedokteran Gigi Indonesia Jurnal Media Gizi Indonesia (MGI) The Indonesian Biomedical Journal Padjadjaran Journal of Dentistry Majalah Kesehatan FKUB AL-MAIYYAH AcTion: Aceh Nutrition Journal Jurnal Budaya Nusantara Journal of Epidemiology and Public Health Journal of Health Policy and Management Martabe : Jurnal Pengabdian Kepada Masyarakat Amerta Nutrition Unnes Journal of Public Health Jurnal Farmasi Higea Jurnal Desain CERIA (Cerdas Energik Responsif Inovatif Adaptif) Jurnal Ilmu Kesehatan Jurnal Kefarmasian AKFARINDO Ilomata International Journal of Management El Banar: Jurnal Pendidikan dan Pengajaran Jurnal Aisyah : Jurnal Ilmu Kesehatan Reswara: Jurnal Pengabdian Kepada Masyarakat Al-MAIYYAH : Media Transformasi Gender dalam Paradigma Sosial Keagamaan SENADA : Semangat Nasional Dalam MengabdI Jurnal Farmasi dan Sains Indonesia (JFSI) Narra J Pengmasku Caring : Jurnal Pengabdian Masyarakat Jurnal PADAMU NEGERI (Pengabdian pada Masyarakat Bidang Eksakta) Smart Society: Community Service and Empowerment Journal Jurnal Pendidikan Dasar Cipta Mitra Teras: Jurnal Terapan Pengabdian Masyarakat Magenta Journal of Community Empowerment Malacca Pharmaceutics Darma Cendekia Bencoolen Journal of Pharmacy Kreativasi: Journal of Community Empowerment Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Abdimas Kesehatan Jurnal Abdimas Bencoolen Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Dian Handayani
Department Of Nutrition, Faculty Of Medicine, Universitas Brawijaya, Jl. Veteran, Malang 65145
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Journal : Amerta Nutrition

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Pemberian Serbuk Daun Kelor (Moringa oleifera) terhadap Perbaikan Profil Lipid dan Ketebalan Aorta pada Tikus Model Prediabetes Mellitus: Pemberian Serbuk Daun Kelor terhadap Perbaikan Profil Lipid dan Ketebalan Aorta pada Tikus Model Prediabetes Melitus Ariestiningsih, Ayuningtyas Dian; Cempaka, Anggun Rindang; Kusumastuty, Inggita; Cahyaningrum, Aladhiana; Setiawati, Sindi; Arintya, Diandra; Azmi, Ulul; Salwa, Putri; Malahayati, Huzaifah; Wibowo, Rizka Azhari; Handayani, Dian
Amerta Nutrition Vol. 8 No. 2 (2024): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v8i2.2024.278-289

Abstract

Background: Consumption of beverages and processed foods with high fructose content has increased recently. This condition increases the risk of metabolic syndrome, which include insulin resistance, impaired lipid profile, and elevated blood pressure. Moringa leaves (Moringa Oleifera), with their bioactive compounds that function as antioxidants, are known to improve fat metabolism and blood glucose. Objectives: The purpose of this study is to analyze the effect of Moringa Oleifera leaf powder and quercetin in controlling metabolic syndrome conditions by improving lipid profiles and aortic thickness in prediabetes mellitus (pre DM). Methods: This experimental research used a post-test-only control group design approach. A total of 35 male Wistar rats were divided into 5 groups such as group K0 (standard feed), E1 (66% fructose probe for 16 weeks), E2 (66% fructose probe for 12 weeks), E3 (66% fructose probe + quercetin 50 mg/kgBW), and E4 (66% fructose probe + Moringa leaf powder 500 mg/kgBW). The examination method for lipid profiles involved serum extraction and enzymatic tests, weighing for white fat tissue mass, while the aorta was examined using a light microscope and histological image analysis. Data analysis used the One-Way ANOVA test. Results: This research showed there are no difference in triglycerides, Low-Density Lipoprotein (LDL) cholesterol, and white adipose tissue significantly between the treatment groups. Level of High-Density Lipoprotein (HDL) cholesterol, total cholesterol, and aortic thickness between the treatment groups are significant differences, with the best results sequentially in groups E2, E1, and K0. Conclusions: The administration of Moringa leaf powder for 4 weeks showed improvements in lipid profiles and aortic thickness in prediabetes mellitus conditions.
Konsumsi Diet Tinggi Lemak Tinggi Fruktosa dalam Jangka Panjang Menurunkan Sensitivitas Insulin dan Merusak Pulau Langerhans pada Tikus Sprague Dawley: Long-Term Consumption of High-Fat-High-Fructose Diet Decreased Insulin Sensitivity and Damaged the Islets of Langerhans on Sprague Dawley Rats Kurniawati, Adelya Desi; Kuswandari, Luh Shanti; Hidayanti, Alfiani; Kusumastuty, Inggita; Sulistyowati, Etik; Handayani, Dian
Amerta Nutrition Vol. 9 No. 3 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i3.2025.469-478

Abstract

Background: Obesity is linked to the rising incidence of type 2 diabetes, with excessive dietary fat intake being one of the primary causes. The development of fat animal models has been discovered to be a standard experimental strategy based on replicating human behaviour in food consumption. Objectives: This study aims to investigate how long-term consumption of a high-fat, high-fructose (HFHF) diet affects the indicators of diabetes mellitus in Sprague Dawley (SD) rats, such as insulin sensitivity, by measuring the HOMA-IR, counting beta cells, and analyzing the histology of the pancreas. Methods: This experiment was conducted with 36 male SD rats in normal and HFHF groups. The normal groups had a modified AIN-93 M, while the HFHF group received a high-fat diet with 30% fructose-based water. Feed and beverage intakes were monitored every 24 hours to calculate daily caloric consumption (energy intake) for 17 weeks. Results: The results demonstrated a significant difference between the normal and HFHF groups in the HOMA-IR levels (insulin sensitivity) and number of pancreatic beta cells (p-value<0.05). This implied that following 17 weeks of HFHF intake, the HOMA-IR level of insulin sensitivity was reduced. However, the islet of Langerhans in pancreatic histopathology seemed damaged in the HFHF rats, as evidenced by the changes in their shape and lower beta cell number. Conclusions: Consuming the HFHF diet over an extended period increased glucose level, decreased insulin sensitivity, and damaged pancreatic histopathology.
Hubungan Antara Indeks Massa Tubuh dan Persen Lemak Tubuh dengan Kebiasaan Makan pada Mahasiswa di Malang: Relationship between Body Mass Index, Body Fat Percentage, and Eating Habits among University Students in Malang Kusumastuty, Inggita; Maulia, Putri Hersya; Dewi, Diva Regita; Oktania, Rizkyah; Nugroho, Fajar Ari; Handayani, Dian
Amerta Nutrition Vol. 9 No. 3 (2025): AMERTA NUTRITION (Bilingual Edition)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i3.2025.419-429

Abstract

Background: In 2023, obesity prevalence in Indonesia was reported at 15.7% in men and 31.2% in women. Eating out has become increasingly common among university students in major cities like Malang due to busy schedules, easy access to food accessibility, and lifestyle changes. Objectives: This study aims to examine the relationship between Body Mass Index (BMI), body fat percentage, and eating habits among university students. Methods: This cross-sectional observational study was conducted at Universitas Brawijaya, Malang, involving 385 respondents. The measured variables included BMI, body fat percentage, and eating habits. Eating habits were assessed using a questionnaire covering five indicators: Takeaway food consumption, eating at home, dining at restaurants, consuming supermarket food, and consuming traditional market snacks. Data were analyzed using the Chi-square test and Logistic Regression. Results: Most respondents were female, lived in dormitories or rented housing, and had a family income below five million rupiahs per month. Among the five eating habit indicators, only restaurant dining showed a significant correlation with BMI and body fat percentage (p-value<0.05), while takeaway food consumption, eating at home, consuming supermarket food, and consuming traditional market snacks were not significantly related (p-value>0.05). Conclusions: Eating habits, in general, showed no significant relationship with BMI and body fat percentage, except for restaurant dining, which was significantly correlated with increased body fat percentage.
Co-Authors . Yanwirasti Abellia, Gaby Achmad Rudijanto Adelya Desi Kurniawati Afra, Wafiqah Akmal Djamaan Al-Rasyid, Harun Alawiya Simanullang, Khairatul Amalialjinan, Nadia Amanda, Savira Intan Amri Bakhtiar Andina Devi Arvita Anggun Faradhita Anggun Rindang Cempaka Anggun, Faradita Anindyanti, Risma Debby Anis Mahmudah, Anis Aniza, Mifta Violina Apriani, Yosi Arintya, Diandra Arizta Primadiyanti Armetristi, Fannisa Arwin Surbakti Asdim Aulani’ Am Ayuningtyas Dian Ariestiningsih Bagus Sumargo, Bagus Bambang Prijadi Bhisma Murti Cahyaningrum, Aladhiana Calista, Rizky Ayu Diella Catur Saptaning Wilujeng Cempak, Anggun Rindang Cynthia Herdiana Safitri Dachriyanus Damaiyana, Tahnia Damayanti Damayanti Debie Rizqoh Delia Komala Sari, Delia Komala Dewi Santosaningsih Dewi, Diva Regita Dhony, Ervia Fahma Dianika, Bani Dienillah, Syifa Sarah Djamaludin, Heder Djoko W. Soeadmadji Djoko Wahono Dominica, Dwi Dwi, Dominica Eddiwan Kamaruddin Edo Galasro Limbong Ekawati, Laily Elena, Felicitas Ellen Ernesta B. Sappu Ellyza Nasrul Endang S. Rahayu Eni Kurniati, Eni Eni Widiyati Ernawati Eti Poncorini Pamungkasari Etik Sulistyowati Evelyne Riandini Fadriyanti, Okmes Fajar Ari Nugroho Fathiyyah Afifah Fajarriani FC Ndaru Ranuhandoko Fenti Mariska Yohana Fernando Fernando, Fernando Fifiet Dwi Tresna Santana, Fifiet Dwi Tresna Firmasyah, Irman Fitria Iswari Fitria Rahmi Frinny Sembiring Galuh, Glaveria Gatya, Mifta Hafidzah, Kurnia Hanifa Setiyawan, Hanifa Harianti Putri, Yona Hayati, Risda Hidayanti, Alfiani Hidayat Sujuti Holipah Holipah Idroes, Ghifari Maulana Iis Purnengsih Inggita Kusumastuty Iva Tsalissavrina Jihan, Salsabila Jonny K. Fajar Kameela, Ishmah Azzah Kamil, Adine Ihsan Kamilla Putri, Dwi Kanthi Permaningtyas Tritisari, Kanthi Permaningtyas Khodijah, Petri Siti Komala Sari, Delia Krisnawati, Hesthi Krisyanella Krisyanella Kumala, Wulan Okta Kuncoro, Safiratuz Zahra ‘Aisy Kurnia, Hafidzah Kurniawati, Noval Kuswandari, Luh Shanti Ladayya, Faroh Leny Budhi Harti Lestari, Dian Fita Lestari, Feny Lubis, Alvi Pauziah M Asmadi M. Aris Widodo Madani, Zikri Muhammad Mahyudin Mahyudin Malahayati, Huzaifah Mariyatun Mariyatun, Mariyatun Martha Sririta Martha Tisna Ginanjar Putri Maulia, Putri Hersya Meganingtyas, Devi Eka Wardani Meki Pranata Mery Sukmiwati Mieke Hemiawati Satari Muh Ade Artasasta Muhammad Iqbal, Roihans Mukhtar, M. Husni Munawaroh, Siti Mar'atul Muniro, Lailatul Nadia Nadia Nasution, Ismet Danial Nia Rochmawati Nindy Sabrina Notriawan, Doni Novilla Anindya Permata Novita Wijayanti Noviyandi Sayuti Nur Azkiyah, Wulan Sari Nur Surachman, Eko Nurfadilah , Sidqia Nurhablisyah Nurhayati, Happy Nurmalita, Shafira Nurrika Azizah, Nurrika Oktania, Rizkyah Oktoviani, Oktoviani Olga Callista, Olga Pradina Purwati Pramesi, Putrika C. Pratiwi, Reza Prianto, Fajar Puspa, Diah Puspita, Wita Hana Putri Nurlita, Septia Putri, Denaranny Gita Putri, Dianita Setya Pradita Putri, Fildzah Karunia Putri, Yona Harianti Rachmawati, Indah Dwi Rahmawati, Reza Reza Pertiwi Reza, Rahmawati Rina Wahyu Winarni Rinaldi Idroes Rini Mustikasari Kurnia Pratama Rini Rita T Marpaung Rizki Saga Putra Rob W.M van Soest Rokhmah, Farida Dwi Romdani, Ayu Nadiyah Permatasari Rosidah Inayati Ruliana Ruliana, Ruliana Rustini Rustini Rustini Rustini S Siswanto Sakti Prabowo, Sakti Salsabila, Adinda Okta Salsabila, Fazira Salsabila, Frisya Nutia Salsabila, Jihan Salwa, Putri Samichah Samichah Sanusi Ibrahim Satya, Lega Sembiring, Frinny SEPTI WULANDARI Setiawati, Sindi Shinta Anggraini, Shinta Siti Salmah Siti Setiati Soemarno Soemarno Sri Andarini Suaida, Desi Holifatus Sudarmono, Andang Suhendra, Maman Sumarah, Kristuti Catur Sumariyono Supratiwi, Ratih Indah Surachman, Eko Nur Suryanto Suryanto Syafruddin Ilyas Syifa Mustika Taher, Muhammad Tanadi, Caroline Teuku Rizky Noviandy Tomi Sukarno Tri Dewanti Widyaningsih TRINA EKAWATI TALLEI Ulul Azmi unance, Lendra Y Usman, Wilda Fhitriany Utmi Arma, Utmi Veibiani, Nindita Arum Versita, Riana Videlia, Videlia Wibowo, Rizka Azhari Widowati Siswomihardjo Widya Rahmawati Wijayanti, Indah Oktari Windarti Windarti Wulansari, Ika Yuni Yanwirasti Yanwirasti Yohanes Kristianto Yona Harianti Putri Yosfi Rahmi Yudha, Sal Prima Yudha S Yufri Aldi Zahra, Felicia Andi