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All Journal IAES International Journal of Artificial Intelligence (IJ-AI) International Journal of Public Health Science (IJPHS) Jurnal Ilmiah Farmasi Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Farmasi Klinik Indonesia Indonesian Journal of Biotechnology Global Medical and Health Communication Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Mutiara Medika: Jurnal Kedokteran dan Kesehatan Pharmacon INDONESIAN JOURNAL OF PHARMACY Pharmascience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Public Health of Indonesia Jurnal Farmasi Sains dan Komunitas THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST Jurnal Surya Medika Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Farmaseutik JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JFIOnline Jurnal Ilmu Kefarmasian Indonesia JCPS (Journal of Current Pharmaceutical Sciences) Medica Hospitalia Jurnal Farmagazine Jurnal Health Sains Journal of Holistics and Health Sciences (JHHS) Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Jurnal Farmasi Klinik dan Sains Borobudur Pharmacy Review Jurnal Permata Indonesia Sciences of Pharmacy Journal of Global Pharma Technology Borneo Journal of Pharmacy Kartika : Jurnal Ilmiah Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian Pharmacon: Jurnal Farmasi Indonesia Jurnal Sains dan Kesehatan Jurnal Farmasi Galenika Indonesian Journal of Pharmacology and Therapy
Dyah Aryani Perwitasari
Fakultas Farmasi, Universitas Ahmad Dahlan
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Common Sense-Self Regulatory Model pada Pasien Diabetes Mellitus Tipe 2 di RSUD Abdul Azis Singkawang, RS Dok II Jayapura dan RSUD Meranti: Common Sense-Self Regulatory Model in Type 2 Diabetes Mellitus Patients at Abdul Azis Singkawang Hospital, Jayapura Doc II Hospital and Meranti Hospital Bambang Purwoko; Dyah Aryani Perwitasari; Imaniar Noor Faridah; Woro Supadmi; Ajeng Diantini
Journal of Holistics and Health Sciences (JHHS) Vol. 5 No. 1 (2023): Journal of Holistics and Health Sciences (JHHS), Maret
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/jhhs.v5i1.260

Abstract

T2DM sufferers during treatment will face stressors that will affect the outcome of therapy and psychological factors. The purpose of this study was to determine the relationship between perception and distress of T2DM patients on adherence, the relationship between adherence to therapy outcomes and quality of life. This study used an observational method with a cross-sectional approach, data was collected prospectively in T2DM patients in Abdul Azis Singkawang Hospital, Dok II Jayapura Hospital and Meranti Hospital. The questionnaires used in this research were the Diabetes Distress Scale (DDS) questionnaire, the Brief Perception Questionaire (B-IPQ), the Morisky Medication Adherence Scale (MMAS-4), and the European Quality of Life-5 Dimensions (EQ-5D). Data analysis using variance based SEM (Structural Equation Modeling), Partial Least Square (PLS) 3.0. The results of the study were 217 DMT2 patients who fulfilled the inclusion criteria dominated by female patients (59%) while men (41%). The index value of quality of life was 0.78±0.26 and visual analog scale was 71.46±14.45. The highest mean perception value was the treatment control domain (8.11±1.89). The mean value of compliance was 2.27±1.36. The results showed that perceptions and stress levels did not have a significant effect on adherence (p>0.05). Compliance did not have a significant effect on therapeutic outcome and quality of life (p>0.05). Stress levels and perceptions did not correlate with outcomes of therapy through adherence (p>0.05) and with quality of life through adherence (p>0.05). The highest mean score on DDS-17 is the therapeutic management domain (2.55±1.08). CSSRM concept conclusion in this study was that adherence did not have a significant effect on outcomes of therapy and quality of life. Perceptions and stress levels did not have a significant effect on compliance. ABSTRAK Penderita DMT2 selama dalam pengobatan akan menghadapi stressor yang akan berpengaruh terhadap luaran terapi dan faktor psikologis. Tujuan penelitian ini untuk mengetahui hubungan antara persepsi dan distress pasien DMT2 terhadap kepatuhan, hubungan kepatuhan terhadap luaran terapi dan kualitas hidup. Penelitian ini menggunakan metode observasional dengan pendekatan cross-sectional, pengambilan data dilakukan secara prospektif pada pasien DMT2 di RSUD Abdul Azis Singkawang, RS Dok II Jayapura dan RSUD Meranti. Kuesioner yang digunakan adalah Diabetes Distress Scale (DDS), Brief-Illnes Perception Questionaire (B-IPQ), Morisky Medication Adherence Scale (MMAS-4), dan European Quality of Life-5 Dimensions (EQ-5D). Analisis data menggunakan SEM (Structural Equation Modeling) yang berbasis varians yaitu Partial Least Square (PLS) 3.0. Hasil penelitian terdapat 217 pasien DMT2 yang memenuhi kriteria inklusi didominasi oleh pasien perempuan (59%) sedangkan laki-laki (41%). Nilai indek kualitas hidup adalah 0,78±0,26 dan visual analog scale 71,46±14,45. Rerata nilai tertinggi persepsi adalah domain kontrol pengobatan (8,11±1,89). Nilai rerata kepatuhan yaitu 2,27±1,36. Hasil penelitian menunjukan bahwa persepsi dan tingkat stress tidak terbukti berpengaruh signifikan terhadap kepatuhan (p>0,05). Kepatuhan tidak berpengaruh signifikan terhadap luaran terapi dan kualitas hidup (p> 0,05). Tingkat stress dan persepsi tidak berkorelasi dengan  luaran terapi melalui kepatuhan (p>0,05) dan dengan kualitas hidup melalui kepatuhan (p>0,05). Nilai rerata tertinggi pada DDS-17 adalah domain manajemen terapi (2,55±1,08). Kesimpulan konsep CSSRM pada penelitian ini adalah kepatuhan tidak terbukti berpengaruh signifikan pada luaran terapi dan kualitas hidup, persepsi dan tingkat stress tidak terbukti berpengaruh signifikan terhadap kepatuhan.
LUARAN TERAPI DAN KUALITAS HIDUP PASIEN DMT2 YANG MENGGUNAKAN INSULIN DI APOTEK X KOTA YOGYAKARTA: THERAPEUTIC OUTCOMES AND QUALITY OF LIFE OF T2DM PATIENTS USING INSULIN AT PHARMACY X YOGYAKARTA CITY Wahyu Rahmatulloh; Menit Ardhiani; Imaniar Noor Faridah; Haafizah Dania; Lalu Muhammad Irham; Dyah Aryani Perwitasari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.742

Abstract

Diabetes Mellitus (DM) merupakan suatu krisis global terutama pada fase urbanisasi yang cepat, perubahan gaya hidup, dan pola makan yang tidak sehat. Prevalensi Diabetes Mellitus Type 2 (DMT2) di Indonesia pada tahun 2018 sebanyak 8.5% yang artinya sebanyak 20.4 juta masyarakat Indonesia menderita DMT2. Berbagai pengobatan yang efektif telah sering didapatkan pasien DMT2 tetapi kadar gula darah masih belum terkontrol sehingga akan mempengaruhi kualitas hidupnya. Tujuan penelitian ini yaitu mengetahui hubungan luaran terapi dengan kualitas hidup pada pasien DMT2 yang menggunakan insulin. Penelitian dilaksanakan  dengan desain cross-sectional, menggunakan instrumen kuesioner Diabetes Quality of Life Clinical Trial Questionnaire (DQLCTQ) dan data rekam medis pada pasien DMT2 yang menggunakan insulin di Apotek X Kota Yogyakarta. Hasil penelitian menunjukkan bahwa dari 50 responden yang memenuhi kriteria inklusi, sebanyak 48% berjenis kelamin laki-laki dan 52% berjenis kelamin perempuan dan didominasi umur >60 tahun sebanyak 60%. Gambaran luaran terapi gula darah puasa (GDP) menunjukkan hasil terkontrol sebanyak 22% dan tidak terkontrol 78%. Kualitas hidup baik pada domain fungsi fisik sebanyak 72%, energi 22%, tekanan kesehatan 92%, kesehatan mental 56%, kepuasan pribadi 44%, kepuasan pengobatan 54%, efek pengobatan 20% dan frekuensi gejala penyakit 60%. Hasil uji chi-square menunjukkan tidak ada hubungan yang bermakna antara luaran terapi dengan kualitas hidup (p>0.05). Kata Kunci : luaran terapi gula darah puasa (GDP), kualitas hidup, diabetes mellitus type 2
DIABETES DISTRESS PADA PASIEN DIABETES MELLITUS TIPE 2 YANG MENGGUNAKAN INSULIN DI APOTEK X : DIABETES DISTRESS ON TYPE 2 DIABETES MELLITUS PATIENTS USING INSULIN IN PHARMACY X Denys Chichi Kusumastuti; Menit Ardhiani; Imaniar Noor Faridah; Haafizah Dania; Lalu Muhammad Irham; Dyah Aryani Perwitasari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.745

Abstract

Diabetes Mellitus Tipe 2 (DMT2) yaitu penyakit kronis yang dapat menyebabkan komplikasi serius. Hal inilah yang membuat penderita DMT2 mengalami distress. Diabetes distress merupakan kondisi yang menggambarkan stress psikologi yang dialami penderita sebagai manifestasi dari rasa takut mengenai hal negatif akibat penyakit diabetes mellitus. Penelitian ini bertujuan untuk mengetahui gambaran distress pada pasien DMT2 yang menggunakan insulin di Apotek X. Penelitian dilakukan menggunakan rancangan cross sectional selama bulan Juni-September 2022 di Apotek X, Yogyakarta. Kriteria responden penelitian adalah semua pasien DMT2 yang datang ke Apotek X dan sesuai dengan kriteria inklusi.  Kriteria inklusinya yaitu: pasien >18 tahun yang terdiagnosa DMT2, telah menggunakan insulin (baik tunggal maupun kombinasi dengan insulin atau oral antihiperglikemia) minimal 3 bulan sebelum rekrutmen penelitian dan bersedia mengikuti penelitian ini. Instrumen penelitian menggunakan kuesioner Diabetes Distress Scale (DDS). Dari 75 responden mengalami diabetes distress tingkat rendah (94,67%) dan tingkat sedang (5,33%). Domain distress yang berpengaruh pada pasien DMT2 yaitu beban emosional (1,30), pengobatan (1,29), interpersonal (1,18), dan dokter/tenaga kesehatan (1,14). Disimpulkan bahwa pasien DMT2 yang menggunakan insulin di Apotek X mengalami diabetes distress tingkat ringan dengan domain yang paling berpengaruh adalah distress beban emosional. Kata kunci: Diabetes Mellitus Tipe 2, Diabetes Distress Scale, Diabetes distress
Publication trend of TMPRSS2 as SARS-CoV-2 receptor during the COVID-19 pandemic Lalu Muhammad Irham; Dyah Aryani Perwitasari; Yudha Rizky Nuari; Wirawan Adikusuma; Haafizah Dania; Rita Maliza; Made Ary Sarasmita; Rocky Cheung; Adi Wira Septama
Pharmaciana Vol 13, No 1 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (678.474 KB) | DOI: 10.12928/pharmaciana.v13i1.24052

Abstract

The Coronavirus Disease 2019 (COVID-19) pandemic has not yet been fully under public health control, which is still currently impacting a large number of people worldwide in 2023. Since the pandemic emerged, the growing number of publications related to TMPRSS2 as a SARS-CoV-2 receptor worldwide has increased rapidly with various findings and qualities. It is important to determine the trend of TMPRSS2 publication as no such studies currently exist that represent the publication trend related to this critical field of study. Here, we employed a bibliometric-based approach to evaluate the research trends of TMPRSS2 mechanistically as the SARS-CoV-2 receptor. We identified 1012 research documents published between 2020 and 2022 for this study. The most common document category was "Research Article" (646 articles, 63.84%) followed by "Review Article" (261 articles, 25.79%), and letters to editors (57 articles, 5.63%). Germany was the most cited country with a total of citations (9400 citations), followed by the USA (6409 citations) and China (1788 citations), respectively. In conclusion, given the impact of COVID-19, this study indicated TMPRSS2 as a SARS-CoV-2 receptor as a timely and highly relevant research topic.
Validity and reliability of “Short-questionnaire of tuberculosis patients’ knowledge about anti-tuberculosis and hepatotoxicity” (SQ-KSH-TB) Dyah Aryani Perwitasari; Muh. Deni Kurniawan; Lalu Muhammad Irham; Imaniar Noor Faridah; Triantoro Safaria; Woro Supadmi; Didik Setiawan; Triantoro Safaria
Pharmaciana Vol 13, No 1 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (381.673 KB) | DOI: 10.12928/pharmaciana.v13i1.24773

Abstract

Until presently, tuberculosis has been a burden to Indonesia, placing the country third among countries with the heaviest tuberculosis burden in the world. Tuberculosis treatment takes a long period and may cause side effects. Therefore, it requires sufficient tuberculosis knowledge on the patients' part for the patients to know of the side effects of anti-tuberculosis and how to deal with them. This research aimed to obtain a short questionnaire of tuberculosis patients' knowledge about anti-tuberculosis and hepatotoxicity (SQ-KSH-TB) which determines patients' knowledge of anti-tuberculosis side effects and how to handle them. This research employed a cross-sectional design and involved 17 public health services (puskesmas) and three hospitals in Yogyakarta Province. The inclusion criteria were patients diagnosed with pulmonary tuberculosis and being in a tuberculosis treatment period with a public health service or a pulmonary hospital in Yogyakarta Province. The exclusion criteria were the patients passing away, having completed a six months treatment or having been receiving treatment for over six months, and being unwilling to cooperate in the research. The questionnaire used in this research was a questionnaire that was developed based on prior research work, containing eight questions on a Guttman scale. Validity and reliability analyses were carried out with Pearson's product-moment correlation and the Kuder-Richardson-20 test, respectively. As many as 194 subjects enrolled in this research. The eight questions in the questionnaire had r count values greater than the r table, hence meeting the validity criterion. Meanwhile, the KR-20 value obtained was 0.721, indicating a good level of reliability. The SQ-KSH-TB was able to meet the validity and reliability criteria, showing applicability in the Indonesian context.
KEPATUHAN DAN LUARAN TERAPI PADA PASIEN DIABETES MELITUS TIPE 2 PENGGUNA INSULIN DI APOTEK X YOGYAKARTA: COMPLIANCE AND TREATMENT OUTCOMES IN TYPE 2 DIABETES MELLITUS PATIENTS USING INSULIN AT PHARMACY X YOGYAKARTA Muhammad Fathurrahman; Menit Ardhiani; Imaniar Noor Faridah; Haafizah Dania; Lalu Muhammad Irham; Dyah Aryani Perwitasari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.743

Abstract

Diabetes melitus (DM) adalah suatu gangguan metabolisme yang ditandai dengan gula darah yang naik secara berlebihan akibat gangguan sekresi insulin, kerja insulin, atau keduanya. Gangguan metabolisme karbohidrat, lemak dan protein pada penderita diabetes disebabkan oleh kurangnya aktivitas insulin pada sel target. Tujuan penelitian ini untuk mengetahui hubungan antara kepatuhan penggunaan insulin dengan luaran terapi klinis di Apotek X. Penelitian ini menggunakan desain studi Cross Sectional dan pengambilan data dilakukan secara prospektif menggunaka kuisioner Medication Adherence Report Scale (MARS) dan data hasil laboratorium. Analisa dapat dilaksanakan menggunakan uji Chi-square. Hasil penelitian menunjukkan kepatuhan tinggi  sebesar 6 responden (30%) dan kepatuhan rendah sebesar 14 responden (70%). Uji chi-square menunjukkan hubungan antara penggunaan insulin dengan HbA1c dengan p-value = 0,01, hubungan antara penggunaan insulin dengan Gula Darah Puasa dengan p-value = 0,024, dan tidak ada hubungan antara penggunaan insulin dengan Gula Darah Sewaktu dengan p-value = 0,807. Hal tersebut menunjukkan bahwa kepatuhan penggunaan insulin mempengaruhi terkontrolnya luaran terapi klinis pasien. Kata Kunci : Diabetes Melitus, Insulin, HbA1c, GDP, GDS, Apotek
UTILIZING A GENOMIC DATABASE FOR IDENTIFYING GENOMIC VARIATION FOR SARS-CoV-2 RECEPTORS Melodia Rezadhini; Lalu Muhammad Irham; Anisa Nova Puspitaningrum; Arief Rahman Afief; Wirawan Adikusuma; Dyah Aryani Perwitasari
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 2 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i2.790

Abstract

Coronavirus disease 2019 (COVID-19) is a severe acute respiratory syndrome caused by the coronavirus SARS-CoV-2. This disease progresses through different stages, and its common symptoms include fever, malaise, dry cough, dyspnea, and pneumonia. Since its discovery in Wuhan, Hubei, China, in December 2019, SARS-CoV-2 transmission has rapidly spread. Unfortunately, the number of cases is increasing beyond expectations, making the spread of confirmed COVID-19 cases easier. To detect specific symptoms in a large population, the relationship between gene variants and patients with COVID-19 can be determined. The data of COVID-19 variations can be obtained from the Ensembl Genome Browser. Herein, the gene associated with 19 variants was selected according to the Haploreg 4.1 version. Additionally, protein expression of missense genes variants using the GTEx portal to determine 2 selected variants: rs200553089 encode the TLR7 gene and rs1061622 encode the TNFRSF1B gene, respectively. The highest protein expression of the TLR7 gene is found in lymphocyte cells, while TNFRSF1B shows the highest expression in the whole blood system. According to the data obtained from the Ensembl Genome Browser, the two most prevalent populations for SNP rs19085059, which is associated with the GPHN gene, are in Africa and East Asia, while SNP rs74956615, linked to the RAVER1 gene, is most prevalent in East Asia. The allele frequency for the TLR7 gene cannot be found in five countries, except in America. Keywords: COVID-19, SARS-CoV-2, Single nucleotide polymorphism, Variants.
Adherence to iron supplementation among anemic pregnant women during 1964-2022: A bibliometric analysis Atmadani, Rizka Novia; Irham, Lalu Muhammad; Perwitasari, Dyah Aryani; Akrom, Akrom; Urbayatun, Siti
Public Health of Indonesia Vol. 9 No. 1 (2023): January - March
Publisher : YCAB Publisher & IAKMI SULTRA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v9i1.647

Abstract

Background: High maternal morbidity and mortality are brought on by the worldwide public health issue of iron and folic acid deficient anemia. The risk to pregnant women’s and their unborn children’s health is reduced when they correctly get and take iron and folic acid supplements. However, people’s inability to adhere to the supplement frequently results in an immense burden. Objective: This analysis focused on describing the field of adherence to iron among pregnant mothers with anemia using bibliometric analysis of the literature from 1981 to 2022 and on analyzing the scientific trends. Methods: We used Scopus as the search engine, using the keywords: Adherence OR Compliance AND Pregnancy OR Pregnant women AND Iron OR Ferrous AND anemia. English journal articles from journals were selected. Results: We retrieved 360 documents during 1981-2022. The result showed trends topics mentioned, mostly pregnancy, anemia, and iron supplementation. The most published articles were from Australia and USA, with Quartal 1 source as the most relevant journal. Conclusion: Although the quantity of publications has increased regularly, it remains below 40 each year. The topic intervention or experimental study, or adherence were still low. Some countries with significantly increased anemia in the last ten years, with the number of publications and collaboration studies remaining high. The modest number indicates that researchers still have many chances to develop better, more productive techniques to enhance adherence and decrease anemia.
Korelasi Tingkat Keparahan Efek Samping Obat Regimen Leucovorin Calcium (Folinic Acid), Fluorouracil, dan Oxaliplatin dengan Kualitas Hidup Pasien Kanker Kolorektal Rinto Susilo; Ajeng Diantini; Kiki Lukman; Dyah Aryani Perwitasari; Didi Rohadi; Tomi Tomi
Jurnal Farmasi Klinik Indonesia Vol 11, No 3 (2022)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2022.11.3.225

Abstract

Adanya kejadian efek samping obat (ESO) pada pasien kemoterapi dapat memberikan resiko pada penurunan kualitas hidup. Penelitian ini bertujuan untuk mengetahui korelasi tingkat keparahan efek samping obat regimen  leucovorin calcium (folinic acid), fluorouracil, dan oxaliplatin (FOLFOX) dengan kualitas hidup pasien kanker kolorektal. Jenis penelitian yang digunakan adalah observasional dengan rancangan studi cross sectional dan pengambilan data secara prospektif tahun 2020-2021 di 3 rumah sakit yaitu RSUP X, RSUD X dan RSUD Y Cirebon. Data yang diambil berupa kejadian efek samping obat baik jenis dan jumlahnya, tingkat keparahan efek samping serta tingkat kualitas hidup. Instrumen yang digunakan adalah Hartwigh et. al. dan kuesioner EORTC QLQ c-30 versi 3 dalam Bahasa Indonesia. Analisis korelasi dengan Pearson Correlation. Jumlah sampel yang didapatkan sebanyak 43 pasien. Jenis ESO yang paling banyak adalah mual, sedangkan yang paling parah stomatitis dan muntah. Skor kualitas hidup pasien yang mengalami ESO yaitu kualitas hidup  global 66,26, kualitas hidup fungsional 71,98 dan kualitas hidup gejala 31,29. Korelasi antara tingkat keparahan efek samping obat dengan kualitas hidup domain global sebesar -0,421, kualitas hidup domain fungsional sebesar -0,638, dan kualitas hidup domain gejala sebesar 0,722. Tingkat keparahan efek samping obat berkorelasi dengan kualitas hidup pasien. Identifikasi efek samping obat dan tingkat keparahannya sejak dini tentu dapat mencegah penurunan kualitas hidup pasien.
Validity and reliability of the world health organisation-five well being index (WHO-5) questionnaire in early detection of depression during Covid-19 pandemic in Yogyakarta Mutmainnah Siradjuddin; Dyah Aryani Perwitasari; Lalu Muhammad Irham; Haafizah Dania; Tetie Herlina
Pharmaciana Vol 13, No 2 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v13i2.24319

Abstract

The Covid-19 pandemic in Indonesia, including Yogyakarta, has created a psychological impact on the community. One of the psychological impacts is depression. This issue can be overcome by early detecting depression using an instrument called the World Health Organization-Five Well-Being Index (WHO-5). Unfortunately, this instrument is currently unavailable in the Indonesian version. Therefore, this study aims to obtain a valid and reliable Indonesian version of the WHO-5, which can later be used by pharmacists as an instrument to early detect depression in Indonesia, especially in Yogyakarta. This research employed a cross-sectional design. The research subjects were people who visited Apotek UAD 1 and 2, who met the inclusion and were not included in the exclusion criteria. The WHO-5 questionnaire proceeded through a translation process from the English version to the Indonesian version. The original version of the WHO-5 questionnaire, which was the final translated version, was tested on 40 respondents to gain its validity and reliability. The analysis of the validity test using the Pearson Correlation of five questions on the WHO-5 questionnaire has revealed an average value of r = 1, indicating that the questionnaire is valid. The result of the reliability test with Cronbach Alpha is 0.853. In conclusion, the Indonesian version of the WHO-5 questionnaire meets the validity and reliability criteria so that the questionnaire can apply to the community.
Co-Authors Abdi Wira Septama Adi Wira Septama Adnan Adnan Adnan Adnan Adnan Adnan Adnan, Adnan Adriyanto Rochmad Basuki Agung Permata Ahmad Azrul Zuniarto Aisyi, Mururul Ajeng Diantini Ajeng Diantini Akrom, Akrom Ambarwati, Sindy Cisna Anak Agung Gede Sugianthara Ananda Muhammad Naafi Ananda Muhammad Naafi, Ananda Muhammad Andalusia, Rizka Andriana Sari Andriana Sari Andriana Sari Andriana Sari Angella, Widi Anisa Nova Puspitaningrum Anisa Nova Puspitaningrum Annisa Annisa Awalia Rahma MH Sibadu Ardan Kensanovanto Arief Muttaqien Arief Rahman Afief Arifin, Bustanul Ariska Wigatiningtyas Astagiri Yusuf, Prasandhya Athika Darumas Putri Aulia Rahman B Simanjuntak, Lamhot Baiq Adelina Atbam Munawwarah Baiq Nurbaety Bambang Purwoko Barkah Djaka Purwanto Barkah Djaka Purwanto Baroroh, Faridah Bayu Prio Septiantoro Bayu Prio Septiantoro Bayu Prio Septiantoro Bayu Tri Murti Berry H Putra Boisi, Cici Feronika Bramadi Arya Bustanuddin As Suaidy Bustanul Arifin Bustanul Arifin Candradewi, Susan Fitria Cheung, Rocky Cut Fatia Ulfa Cut Fatia Ulfa Damayanti, Elok Dania Haafizah Darwis Darwis darwis darwis, darwis Denys Chichi Kusumastuti Desi Kusumawati, Desi Desty Kusumaningsih Dewi Wulandari Dewi Wulandari Dewi, Masita Sari Dian Prasasti Dian Prasasti Dias Ananda Sulistya Didi Rohadi Didik Setiawan Didik Setiawan Dwi Utami Eka Wuri Handayani Elli Nur Hayati Endang Darmawan Endang Darmawan Endang Darmawan Endang Yuniarti Endang Yuniarti Endang Yuniarti Esty Elvinda Farah Bidara Farida, Imaniar Noor Faridah Baroroh Faridah, Imaniar Fatimah Sri Kurniawati Fatimah, Salma Auliya Fatkhiya, Musa Fitri Febriana, Sri Awalia Febriana, Sri Awalia Fitri Nur Mahmudah Fredrick Dermawan Purba Gina Noor Djalilah Gugun Suhendra Gugun Suhendra Gurning, Sri Handayani Haafizah Dania Haafizah Dania Haafizah Dania Haafizah Dania Haafizah Dania Haafizah Dania Hadiq, Shabran Handayani, Eka Wuri Haridini Intan Mahdi Haridini Intan Mahdi Haridini Intan Mahdi Hasniah Hasniah Hazena Misgi Damayanti, Hazena Misgi Hendrik Hendrik Hendy Ristiono, Hendy Herjanti Ratnawiningsih Herjanti Ratnawiningsih Herjuna Hardiyanto Herlina, Tetie Hidayah Karuniawati Ikrimah Nisa Utami Imaniar Faridah Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Intan Fatah Kumara Irma Risdiana Irma Risdiana Irma Risdiana, Irma Iskak, Iskak Islami, Safira Nur Jamhari Jamhari Jarir At Thobari Juwita, Dina Ratna Kania Agustina Kaptein, A.A Khuluq, Husnul Kiki Lukman Kintoko, Kintoko Kodriati, Nurul Kuluq, Muhammad Husnul Kurniawan, Nurcholid Umam Kurniawati, Fatimah Sri Kurniyati, . 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