Claim Missing Document
Check
Articles

Formulasi Sediaan Lip Cream Ekstrak Daun Miana (Coleus scuatellariodes [L] Benth.) sebagai Pewarna Alami Vera Estefania Kaban; Nasri Nasri; Kasta Gurning; Hariyadi Dharmawan Syahputra; Zulmai Rani
INSOLOGI: Jurnal Sains dan Teknologi Vol. 1 No. 4 (2022): Agustus 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v1i4.719

Abstract

Miana leaf (Coleus scutellarioides L.) is a plant that contains anthocyanins that can provide certain dyes. The purpose of this study was to formulate miana leaf extract in lip cream preparations as a natural dye. The research method includes the manufacture of ethanol extract of miana leaves (Coleus scutellarioides L.) by maceration method. The extract formulas used were 25%, 50%, and 75%. The tests carried out included organoleptic tests, homogeneity tests, physical tests, pH tests, irritation tests and color preference tests. The results of the lip cream preparation, the results of the organoleptic examination were declared to have a semi-solid dosage form, distinctive odor and varied colors F1 pink F2 purplish red, F3 blackish red, homogeneity test results were declared homogeneous, stability test results showed that the preparation did not change shape, color and the odor of the preparation for 14 days of storage, the results of the pH test showed that the preparation was still within the permissible pH range on the use of the skin, the test results were declared non-irritating. Miana leaf ethanol extract can be made as a colorant in lip cream preparations.
Formulasi Sediaan Pewarna Pipi dalam Bentuk Padat dengan Menggunakan Ekstrak Buah Buni (Antidesma bunius (L.) Spreng) Anggitha Ningtias; Zulmai Rani; Ridwanto
INSOLOGI: Jurnal Sains dan Teknologi Vol. 1 No. 4 (2022): Agustus 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v1i4.811

Abstract

Buni fruit (Antidesma bunius (L.) Spreng) is a plant that contains anthocyanin pigments that can give a red color. The purpose of this study was to make cheek dye preparations in solid form using buni fruit extract (Antidesma bunius (L.) Spreng) as a dye. The extract was obtained by maceration using 96% ethanol containing 2% citric acid. The cheek coloring formula that was made was using buni fruit dye with a concentration of 10; 12.5; 15 and 17.5%. The tests carried out include: physical quality inspection (homogeneity, polish test, crack test), irritation test, and stability test. Formula with a concentration of 10% produces a pale cream color; preparation with a concentration of 12.5% ​​produces a cream color, a concentration of 15% produces a weak pink color and a concentration of 17.5% produces a dark pink color. The results of the physical quality examination of the preparation showed that the preparation had a homogeneous color, good polish at a concentration of 17.5% because it produced a clear pink color during polishing and did not crack when dropped from a height of 25 cm. Preparations are not irritating. From the observation of the shape, it was found that all the cheek coloring preparations made did not change shape from the initial form of printing for 90 days at room temperature storage. From the results of color observations, all preparations made remained stable during storage at room temperature for 50 days, on day 55 the color of the preparation began to fade, this was due to unstable anthocyanins. The odor of the preparation remained stable in storage for 90 days of observation at room temperature. These results indicate that buni fruit extract can be used as a colorant in cheek coloring preparations.
Antioxidant Activity Test Of Methanol Extract Of Gaharu (Aquilaria Malaccensis Lam.) Bark With Dpph (1,1 Diphenyl-2-Picrylhydrazyl) Method Ridwanto Ridwanto; Asep Trizaldi; Zulmai Rani; Anny Sartika Daulay; Haris Munandar Nasution; Dikki Miswanda
International Journal of Health and Pharmaceutical (IJHP) Vol. 3 No. 2 (2023): May 2023
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v3i2.123

Abstract

Gaharu (Aquilaria malaccensis Lam.) is one of the natural ingredients that can be used as an antioxidant. Antioxidants are compounds that can inhibit free radical reactions in the body. Free radicals have an impact on the pathogenesis of several diseases in humans due to oxidative stress in cells. The purpose of this study was to determine the class of secondary metabolites of agarwood bark and antioxidant activity and to compare the value of IC50 (Inhibitory concentrations) of the methanol extract of agarwood bark with the IC50 of vitamin C in the DPPH method using UV-Vis spectrophotometry. The methanol extract of agarwood bark was macerated using methanol, then determined the content of secondary metabolites of Simplicia. The determination of antioxidant activity was carried out on the methanol extract of agarwood bark with the addition of DPPH at various concentrations. The sample concentrations were 20, 40, 60, 80, and 100 µg/mL.. As a comparison, vitamin C was used with concentrations of 4, 8, 12, 16 and 20 µg/mL.. Then they calculated percent attenuation (% inhibition) and the value of IC50. The results of the screening on the methanol extract of agarwood bark contained chemical compounds such as flavonoids, saponins, and tannins. The determination of antioxidant activity was carried out using a UV-Vis spectrophotometer with the DDPH method. The results were obtained from the methanol extract of the bark of agarwood, which has antioxidant activity in the strong category with an IC50 value of 94.59 µg/mL.and vitamin C in the very strong category with an IC50 value of 22,11 µg/mL.
Profil Penggunaan Obat Antidiabetes Tipe II Di RSUD Dr. Husni Thamrin Natal Medan, Sumatera Utara Robiatun - Rambe
JURNAL FARMASI DAN MAKANAN Vol 6 No 1 (2022): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i1.2971

Abstract

The pancreas does not produce enough insulin or the body cannot use the insulin it produces effectively. Insulin is a hormone that regulates the balance of blood sugar levels. (hyperglycemia). This research was conducted with a non-experimental descriptive method with a cross-sectional design that was carried out every month. Sampling was carried out in the internal medicine section of RSUD by Dr. Husni Thamrin Natal. Samples were taken retrospectively every month using secondary data, namely medical records of patients using oral antidiabetics (drugs) in the period from January to June 2019. The data obtained was presented in the form of table proportions and graphs. The results showed that the largest percentage of use of antidiabetic drugs was male, as many as 67 people (57.26%), over 50 years old, as many as 97 people (82.91%), and the type of work was self-employed for as many as 47 people (40, 17%). The most widely used antidiabetic drug groups are the biguanide groups (75.17%), the combination type of drug with a combination of metformin and glimepiride (93.33%), and the frequency of use of the drug metformin (74.15%). Based on the results of the study, it can be concluded that the highest prevalence is in the male sex, and the average age is over 50 years. The pattern of prescribing antidiabetic drugs based on the most widely used drug class is the biguanide group, which is a combination of metformin and glimepiride types of drugs, and the frequency of drug use is metformin.
UJI TOKSISITAS KITOSAN CANGKANG KERANG BULU (Anadara antiquata) DENGAN METODE BRINE SHRIMP LETHALITY TEST (BSLT) Nadila Indra Sepvina; Ridwanto Ridwanto; Zulmai Rani
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 7 No 2 (2022): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v7i2.1023

Abstract

Shellfish is one of Indonesia's fishery commodities which is increasing every year, one of which is blood clams and feather shells, which are easily found in Southeast Asia and East Asia. Shellfish also have great potential so that it has an impact on the increasing waste that is allowed to accumulate without any handling of the pollution that exists in the environment and society. One alternative to the use of waste from feather shells to have a high use value is to isolate it into chitosan. The purpose of this study was to investigate the utilization of shellfish waste into chitosan and to determine the LC50 value of the chitosan produced. The analysis carried out was the toxicity test of chitosan from shellfish shell waste on Artemia salina Leach shrimp larvae using the Brine Shrimp Lethalitiy Test (BSLT) method with various concentrations of 100; 250; 500; 750; and 1000 µg/mL, and determining the value of LC50 by probit analysis. Based on the results of the toxicity test of chitosan from shellfish waste, the LC50 value was µg/mL. These results indicate that chitosan from shellfish waste has no toxic effect on Artemia salina Leach shrimp larvae.
PELATIHAN PEMBUATAN ECO ENZYME SEBAGAI UPAYA PEMANFAATAN SAMPAH RUMAH TANGGA DI DESA SIDOMULYO Fatma Dwi Jati; Dikki Miswanda; Bambang Hermanto; Zulmai Rani; Moondra Zubir; Siti Rahmah
AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Vol. 6 No. 2 (2022): Amaliah: Jurnal Pengabdian Kepada Masyarakat
Publisher : LPPM UMN AL WASHLIYAH

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/ajpkm.v6i2.1829

Abstract

Kegiatan pengabdian ini dilatarbelakangi oleh banyaknya timbunan sampah rumah tangga yang disebabkan rendahnya pengetahuan masyarakat Desa Sidomulyo, Kecamatan Sibiru – Biru, Kabupaten Deli Serdang, tentang pengelolaan sampah rumah tangga. Sampah rumah tangga seperti sayur dan buah dapat dimanfaatkan menjadi produk eco enzyme yang mempunyai banyak manfaat. Tujuan kegiatan pengabdian ini adalah untuk meningkatkan pemahaman dan keterampilan masyarakat dalam mengolah sampah organik rumah tangga menjadi eco enzyme dan lebih lanjut lagi dapat meningkatkan penghasilan masyarakat dengan komersialisasi produk eco enzyme yang dihasilkan. Metode pelaksanaan kegiatan ini adalah ceramah, diskusi, demonstrasi, dan praktek. Sosialisasi tentang pengelolaan dan pemanfaatan sampah organik rumah tangga menjadi produk eco enzyme, serta pemasaran produk eco enzyme dilaksanakan dengan metode ceramah dan diskusi. Cara pembuatan eco enzyme dari sampah organik rumah tangga dilaksanakan dengan metode demonstrasi dan praktek oleh peserta kegiatan. Setelah kegiatan pengabdian ini dilaksanakan, pemahaman peserta tentang materi kegiatan, meningkat sebesar 72.25% dibandingkan sebelum mengikuti kegiatan. Adanya peningkatan pemahaman peserta membuktikan kegiatan pelatihan pembuatan eco enzyme dari sampah organik rumah tangga telah berhasil dilakukan pada masyarakat mitra.
Mekanisme Antibakteri Ekstrak Etanol Daun Kemangi (Ocimum basilicum L.) terhadap Salmonella typhi Nasri Nasri; Vera Estefania Kaban; Denny Satria; Hariyadi Dharmawan Syahputra; Zulmai Rani
Journal of Pharmaceutical and Health Research Vol 4 No 1 (2023): February 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i1.3176

Abstract

Infectious diseases are conditions that can be brought on by a variety of different organisms, including bacteria, viruses, fungi, and parasites. Typhoid fever is an example of an infectious disease that frequently causes the body's defenses to come under attack. The fever associated with typhoid is a leading cause of death around the world. Infection with the bacterium Salmonella typhi is considered to be one of the potential causes of typhoid fever. When antibiotics are used to treat bacterial infections, there is a risk that the bacteria will become resistant to the medication. In day-to-day life, basil leaves are utilized both as a cooked vegetable and as a fresh vegetable. The antibacterial properties of kemangi leaves have yet to be fully uncovered. The purpose of this study was to investigate the various mechanisms that are involved in antibacterial activity. These mechanisms include cell leakage, minimum inhibitory concentration, minimum killing concentration, and antibiofilm activity. The minimum inhibitory concentration (MIC) was determined with the agar diffusion method, the minimum biofilm forming concentration (MBC) was determined with the staining method, and cell leakage was determined with UV-VIS spectrophotometry at wavelengths of 260 nm (DNA) and 280 nm (protein). Additionally, the formation of anti-biofilms was determined with microtiter plates and gentian violet staining. In the moderate category, the MIC value tests showed a concentration of 0.3125% with an inhibition zone value of 6.80 0.05 mm. These results were obtained from the MIC value. Because there was no detectable bacterial growth on the streaked medium, KBM was obtained at a concentration of 10%. At wavelengths of 260 and 280 nanometers, leakage cells show absorbance absorption. The percentage of biofilm activity that is measured when the concentration is increased to 25% is 44.82%. In conclusion, the ethanol extract of basil leaves possesses a possible antibacterial mechanism against Salmonella typhi. This was discovered through testing.
PEMANFAATAN LIMBAH MINYAK GORENG SEBAGAI SABUN NATURAL ECO ENZYM DI DESA KOLAM PASAR 13 KECAMATAN PERCUT SEI TUAN Anggitha Ningtias; Zulmai Rani; Kiki Rawitri
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 2 (2023): Volume 4 Nomor 2 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Kegiatan pengabdian kepada masyarakat yang dilaksanakan berupa edukasi kepada masyarakat. Pelaksanaan pengabdian kepada masyarakat dilakukan dengan penyuluhan terlebih dahulu kemudian baru melakukan pendampingan praktek penyuluhan tersebut. Pemanfaatan minyak jelantah menjadi sabun cuci juga bisa meningkatkan kesejahteraan karena bisa menghemat pengeluaran keluarga dan bisa dikembangkan lebih lanjut bukan tidak mungkin bisa dijadikan salah satu sumber pendapatan keuarga. Selain mengedukasi kepada ibu-ibu di Desa Kolam Pasar 13 Kecamatan Percut Sei Tuan tentang pengelolaan minyak jelantah sebagai sabun padat untuk mencuci piring, Tim Dosen UMN Al-Washliyah juga mengedukasi pembuatan larutan eco enzyme yang juga memiliki banyak manfaat yaitu sebagai larutan pembersih serbaguna, pupuk tanaman dan melestarikan lingkungan. Larutan pembersih komersial yang ada sekarang berpotensi mencemari udara, tanah, air, sungai, dan laut. Penggunaan cairan organik ini sebagai larutan pembersih alami sangat membantu menjaga lingkungan.Pada kegiatan tersebut dihadiri sekitar 25 PKK dari Desa Kolam Pasar 13, dan pada kesempatan tersebut disampaikan kepada seluruh PKK untuk selalu menjaga kelestarian lingkungan dari limbah rumah tangga, salah satunya adalah dengan mengelolah limbah minyak jelantah menjadi sabun cuci piring dan mengelolah limbah kulit buah, dan sisa sayuran menjadi larutan eco enzyme yang kaya akan manfaat. Kegiatan Pengabdian Kepada Masyarakat tersebut mendapat sambutan yang luar biasa dari seluruh pihak terkait. Tim pengabdian mengucapkan terima kasih kepada Ibu Kadus Desa Kolam, Kader PKK Desa Kolam sehingga kegiatan pengabdian tersebut berjalan dengan sukses dan lancar.
Formulasi Sediaan Gel dari Ekstrak Metanol Biji Alpukat (Persea americana Mill.) Sebagai Penyembuh Luka Sayat Pada Tikus Jantan (Rattus norvegicus) Vera Estefania Kaban; Nasri Nasri; Hariyadi Dharmawan Syahputra; Raissa Fitri; Zulmai Rani; Muhammad Fauzan Lubis
Herbal Medicine Journal Vol 5 No 2 (2022): Herbal Medicine Journal
Publisher : Program Studi S1 Farmasi, STIKES Senior, Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (373.901 KB) | DOI: 10.58996/hmj.v5i2.50

Abstract

The avocado (Persea americana Mill.) is a fruit that is often found. This versatile fruit has many benefits for humans. The benefits of avocado are as anti-hyperlipidemic, analgesic, anti-inflammatory, anticonvulsant, hypoglycemic, hypercholesterolemic, wound healing and prevent cancer. The aims of this study was to make avocado seed methanol extract into a gel preparation and to determine the effect of avocado seed methanol extract gel and at what concentration the effective treatment for wounds in mice and its comparison with Star Ag gel as a positive control. The research was conducted using an experimental method. The manufacture of avocado seed methanol exstract was carried out by maceration method using methanol as a solvent. The result of the study were statistically analyzed using One Way Anova. The result of the data analysis at a concentration of 5% obtained a sig value <0,05. Based on One Way Anova analysis of the five treatments, the most effective was avocado seed methanol extract gel with a concentration of 5%.
Evaluation Of Drug Storage System In A Pharmacy Of Medan City Based On Pharmaceutical Services Standards Syilvi Rinda Sari; Muhammad Yunus; Kiki Rawitri; Sri Wahyuni; Zulmai Rani; Hindri Syahputri
International Journal of Science, Technology & Management Vol. 4 No. 4 (2023): July 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i4.872

Abstract

Pharmacy is a place where pharmaceutical services are held by pharmacists who are responsible for patients. Pharmaceutical services in pharmacies are related to drugs with the aim of achieving definite results to improve the quality of life of patients. So the management of drugs in pharmacies needs to be done properly and precisely to ensure the availability of sufficient and quality drugs in order to achieve optimal service goals by implementing a storage system that is in accordance with pharmaceutical service standards no.73 of 2016. Therefore the purpose of this research is to evaluate the drug storage system in one of the Medan city pharmacies based on pharmaceutical service standards. This research is descriptive with retrospective data collection. The data obtained were grouped into quantitative data presented in tabular form to see visual comparisons, and qualitative data obtained through observation and interviews with informants. The results showed that in several indicators of drug storage in one of the Medan city pharmacies based on Permenkes No. 73 of 2016 there are still those that have not complied with, namely in the preparation of LASA drugs and writing document numbers on drug stock cards. Meanwhile, the standard drug storage indicators are the columns on the stock card consisting of receipt or dispensing date, receipt or disbursement document number, source of origin of the drug, no. batch/no. Lot, expiry date, receipt and disbursement amount, remaining stock, and officer's initials, as well as suitability for drug storage based on dosage form, alphabetical order, and FEFO and FIFO storage methods. Based on the results of the study it was concluded that the drug storage system carried out in one of the pharmacies in the city of Medan did not meet pharmaceutical service standards based on Permenkes No. 73 of 2016.
Co-Authors A'dilah, Nur Abadi, Hafizhatul Adjelie, Tiara Adli Nuzula Rahmah Adyani Maulinda Afridah, Nurul Ilmi Ahmad Rasyid Ridho Alviana, Liya Amelia Kudadiri Andjelie, Tiara Ani Sutiani Ani Sutiani Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Aprilia, Hijjatun Arifin, Khairil Fikri Arrosty, Muflizah Asep Trizaldi Athaillah, Athaillah Audry Pratiwi Aulia Fitri Aulia Fitri, Aulia Auza , Maharani Azhar, Gustika Bambang Hermanto Bambang Hermanto Beby Noplya Wulandari BJ Sutrisna Chandra, Putra Christica Ilsanna Surbakti Daulay, Anny S. Dea Anggreini Denny Satria Dewi, Sri Harti Dikki Miswanda Dinda Sari Utami Emma Susanti Erma Susanti Evi Depiana Gultom Evi Depiana Gultom Evi Depiana Gultom Fadhlah Al-Uyun Nasution Fajri, Fajrilda Aqilah Fatma Dwi Jati Fauziah Erna Witular Panggabean Ferendina, Imelda Fithri Pulungan, Ainil Fitri, Nurul Fitri, Raissa Gabena Indrayani Dalimunthe Ginting, Grace Anastasia br Ginting, Ovalina Sylvia Br Ginting, Ovalina Sylvia Br. Hanafis Sastra Winata Harahap, Sumiyarni Haris Munandar Nasution Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hasibuan , Fika Miah Sasmitha Hasibuan , Nabila Hasim Hasibuan, Zulfiana Ramadhani Hindri Syahputri Humaira, Annisa Husna, Miftahul Indrayani, Gabena Inna Myesha Julia Reveny Karo Sekali, Elva Swandi Kasta Gurning Khairunnisa , Ardina Khan, Sahrani Nazwa Kiki Rawitri Kiki Rawitri Lestari, Amanda Putri Lestari, Kurnia Dwi Lilik Septiana Lilik Septiana Linda, Rosa Lubis, Minda Sari Lubis, Nurazizah M. Alfaruqi Maghfirah, Dini Mainal Furqan Maryanti Yuza Matondang , Fikriyah Hafni Maulana Putri, Yasinta Mira Febrina, Mira Monica Suryani Moondra Zubir Muhammad Agus Muljanto Muhammad Amin Nasution Muhammad Fauzan Lubis Muhammad Yunus Muhammad Yunus Mukti, Ridho Munandar, Verissa Nadila Indra Sepvina Nasri Nasri Nasri Nasri Nasri Nasri, Nasri Nazuhra, Oca Nia Novranda Pertiwi Nindya Indah Damayanti Ningtias, Anggita Ningtias, Anggitha Nomi Noviani Nur Ain Thomas Nur, Hijrotun Nurdalilah, Nurdalilah Nurhayati Nurhayati Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Pasar Maulim Silitonga Pertiwi, Rahma Pitaloka, Syifa Amilia Puteri, Cut Intan Annisa Putra, Andhika Dharma Putri Khairani Rafita Yuniarti Rahma Dona Raissa Fitri Rambe, Robiatun Ratih Paramitha Rawitri, Kiki Reza Irma Ricky Andi Syahputra Ricky Andi Syahputra Ridho, Ahmad Rasyid Ridwanto Ridwanto Rinda Sari, Sylvi Ritonga , Nur Sakina Rizki, Dewi Rizki, Vitri Dea Robiatun Rambe Rukmana, Siti Sagala, Hasel Untung Bersinar Samran, Samran Sari Lubis, Winda Sari, Farida Sari, Syilvi Rinda Sari, Sylvi Rinda Sartika Daulay, Anny Savitri, Novia Herma Septiana, Lilik silalahi, zahra salsabila Sindi, Sindi Sipahutar, Rizki Anjani Siregar , Misbah Siti Anisa Siti Rahmah Siti Rahmi Ningrum Sony , Suyefri Sri Wahyuni Sri Wahyuni Sri Wahyuni Suci, Nurul Sulwiyatul K Sani Supiyani, Supiyani Syafa Nadira Ashiilah Syahputra, Ricky Andi Syarifah Nadia Syilfia Hasti Tania, Chyntia Glori Tarigan, Eni Surabini Urip Harahap Uswatun Nisa, Uswatun Vera Estefania Kaban Virda Nurmazela Widya, Rizka Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Haryani Yuliatil Adawiyah Harahap Yuniarti , Rafita Yuniarti, Rafita Zahira Ahmad, Madani Ziza Putri Aisyia Fauzi Zulfikri Zulfikri Zulhij, Fizrya