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All Journal Journal of Agromedicine and Medical Sciences Pharmascience Window of Health : Jurnal Kesehatan JOPS (Journal Of Pharmacy and Science) Journal Syifa Sciences and Clinical Research (JSSCR) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Dunia Farmasi Jurnal Ilmiah Manusia dan Kesehatan ad-Dawaa : Journal of Pharmaceutical Sciences Indonesian Journal of Pharmaceutical and Clinical Research Jurnal Aisyah : Jurnal Ilmu Kesehatan Community Development Journal: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Health Research International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Chemical Science and Technology Jurnal Kesehatan Tambusai JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal EduHealth FORTE JOURNAL Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmanesia Jurnal Sains dan Teknologi International Journal of Health and Pharmaceutical (IJHP) SENTRI: Jurnal Riset Ilmiah Sciences of Pharmacy FARMASAINKES PCJN Pharmaceutical and Clinical Journal of Nusantara Herbal Medicine Journal Journal of Pharmaceutical and Sciences. Media Farmasi Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara Jurnal Akademika Kimia Jurnal Sains dan Kesehatan
Zulmai Rani
Universitas Muslim Nusantara Al-Washliyah, Medan, Indonesia
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Cytotoxicity Test of Bandotan Herbal Ethanol Extract (Ageratum conyzoides L.) Using the Brine Shrimp Lethality Test (BSLT) Method Sari, Farida; Ridwanto, Ridwanto; Daulay, Anny S.; Rani, Zulmai
Jurnal Akademika Kimia Vol. 13 No. 1 (2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24775185.2024.v13.i3.pp14-19

Abstract

Cytotoxic activity is a process that can induce cell death. One of the plants that has cytotoxic properties is bandotan (Ageratum conyzoides L.). The purpose of this study was to identify the class of secondary metabolites present in the ethanol extract of Bandotan herb and to evaluate its cytotoxicity by determining the LC50 value using the Brine Shrimp Lethality Test (BSLT) method. This research includes phytochemical screening and cytotoxicity testing of an ethanol extract of Herba bandotan using the BSLT method. BSLT is the first method for cytotoxicity testing using Artemia salina Leach larvae at the nauplii stage. Used in the BSLT method because it has similar responses with mammals, namely DNA-dependent RNA polymerase in Artemia salina Leach, similar to DNA-dependent RNA polymerase in mammals. By phytochemical screening, the secondary metabolites in Herba Bandotan (Ageratum conyzoides L.) are alkaloids, flavonoids, saponins, steroids, and tannins. Based on the results of the cytotoxicity test using the BSLT method, it shows that the ethanol extract of Herba bandotan (Ageratum conyzoides L.) has the potential to be anti-cancer because it has an LC50 value of 255.1915 g / mL, which is included in the toxic category and has the potential to be anti-cancer. Potential as an anticancer agent in the BSLT test if it has an LC50 value < 1000 µg / mL.
Characterization and Phytochemical Screening of Rambai Leaf Extract (Baccaurea motleyana Mull.Arg) from Peureulak, Aceh. M. Alfaruqi; Rani, Zulmai; Indrayani, Gabena; Nasution, Haris Munandar
PCJN: Pharmaceutical and Clinical Journal of Nusantara Vol. 3 No. 02 (2025): PCJN: Pharmaceutical and Clinical Journal of Nusantara
Publisher : CV. Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58549/pcjn.v3i01.91

Abstract

The rambai plant (Baccaurea motleyana Mull.Arg) contains flavonoid compounds scattered in various parts of the plant such as roots, stems, bark, twigs, leaves, fruit, flowers and seeds. Rambai leaves have various properties that have been empirically proven to cure various diseases, including wound medicine, smallpox medicine, and flu powder. The aim of this research is to find out whether rambai leaf extract contains phytochemicals and to determine the characteristics of rambai leaf extract. Phytochemical screening of rambai leaf extract (Baccaurea motleyana Mull.Arg), including examination of flavonoids, tannins, saponins, steroids/triterpenoids, alkaloids and glycosides. Phytochemical screening was carried out on simplicia powder and simplicia extract and characterization of simplicia was carried out. Testing the water content of rambai leaves was 8%, the water soluble essence content was 33.22%, the ethanol soluble essence content was 13.163% and the total ash content was 5.1% and the acid insoluble ash content was 0.3%. Rambai leaf extract positively contains alkaloids, flavonoids, saponins, tannins, steroids/triterpenoids, and glycosides.
Pembuatan dan Aktivitas Anti-Acne Nano Essence Sheet Mask Ekstrak Bonggol Nanas (Ananas comosus (L.) Merr) Ritonga , Nur Sakina; Lubis, Minda Sari; Yuniarti , Rafita; Rani , Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.852

Abstract

Pineapple tubers, which are often considered waste, contain chemical compounds such as flavonoids, alkaloids, aPineapple tubers, which are often considered waste, contain chemical compounds such as flavonoids, alkaloids, saponins, tannins, and glycosides. This compound has antibacterial effects, especially against Propionibacterium acnes, which are gram-positive bacteria that cause acne. Anti-acne masks effectively prevent acne by disrupting the growth or killing bacteria through inhibiting microbial metabolism. This research is experimental in nature with Independent Variables: Extract, pineapple tuber simplicia, essence preparation, and nano essence sheet mask. Dependent variables include the physical characteristics of the preparation, as well as anti-acne activity. The extract was made using the maceration method, and then the antibacterial test of the extract was conducted. The preparations were subjected to physical quality tests, irritation tests, and antibacterial tests using the disc method. Orientation test results for the antibacterial activity of pineapple tuber extract against Propionibacterium acne s using the agar diffusion method with disc paper, namely, 3.25% (4.1 mm), 6.25% (4.9 mm), 12.5% (6.4 mm), 25% (7.5 mm), 50% (7.8 mm). The concentration of the preparation was obtained at 12.5% and then tested by PSA ( Particle Size Analyzer ). All particles were below 1000 nm, meeting the requirements. The results of the antibacterial activity test of the preparation showed the following inhibition zones: Blank (0 mm), Essence (9.5 mm), Nano Essence (11.13 mm), Comparator (25.3 mm), Clindamycin (32.3 mm). Good physical quality and can be used as an anti-acne.saponins, tannins and glycosides. This compound has antibacterial effects, especially against Propionibacterium acne s, gram-positive bacteria that cause acne. Anti- acne masks are effective in preventing acne by disrupting the growth or killing bacteria through inhibiting microbial metabolism. This research is experimental in nature with Independent Variables: Extract, pineapple tuber simplicia, essence preparation and nano essence sheet mask. Dependent variables include the physical characteristics of the preparation, as well as anti- acne activity . The extract was made using the maceration method, then the antibacterial test of the extract was oriented.The preparations were subjected to physical quality tests and irritation tests, as well as antibacterial tests using the disc method. Orientation test results for the antibacterial activity of pineapple tuber extract against Propionibacterium acne s using the agar diffusion method with disc paper, namely, 3.25% (4.1 mm), 6.25% (4.9 mm), 12.5% (6.4 mm), 25% (7.5 mm), 50% (7.8 mm). The concentration of the preparation was obtained at 12.5% and then tested by PSA ( Particle Size Analyzer ). All particles were below 1000 nm, meeting the requirements. The results of the antibacterial activity test of the preparation showed the following inhibition zones: Blank (0 mm), Essence (9.5 mm), Nano Essence (11.13 mm), Comparator (25.3 mm), Clindamycin (32.3 mm). Good physical quality and can be used as an anti -acne.
Karakterisasi, Skrining dan Uji Aktivitas Antibakteri Ekstrak Etanol Bunga Kecombrang (Etlingera elatior (Jack) R.M.Sm) terhadap Staphylococcus aureus Khairunnisa , Ardina; Yuniarti, Rafita; Dalimunthe, Gabena Indrayani; Rani, Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.870

Abstract

Background: Torch ginger (Etlingera elatior (Jack) R.M.Sm) is a traditional medicinal plant with potential antibacterial properties due to its secondary metabolites, such as flavonoids, tannins, and terpenoids. Staphylococcus aureus is a pathogenic bacterium causing various infections, and increasing antibiotic resistance necessitates alternative treatments. This study aims to explore the antibacterial potential of torch ginger flower ethanol extract against S. aureus. Objective: This research aimed to characterize the phytochemical content of torch ginger flowers, screen for bioactive compounds, and evaluate their antibacterial activity against S. aureus. Methods: The study employed an experimental design, including phytochemical screening, ethanol extraction (maceration), and antibacterial testing using the disk diffusion method at concentrations of 10%, 30%, 50%, 70%, and 90%. Data were analyzed using one-way ANOVA. Results: Phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, saponins, steroids/triterpenoids, and glycosides. The ethanol extract exhibited antibacterial activity against S. aureus, with inhibition zones of 11.9 mm (weak) at 10%, 16.1 mm (moderate) at 30%, and 21.3–22.5 mm (strong) at 50–90%. Statistical analysis confirmed significant differences (p < 0.05) between concentrations. Conclusion: Ethanol extract of torch ginger flowers demonstrated dose-dependent antibacterial activity against S. aureus, supporting its potential as a natural antibacterial agent.
Konsentrasi Hambat Minimum dan Konsentrasi Bunuh Minimum Ekstrak Dan Nanopartikel Ekstrak Daun Pometia pinnata Terhadap Staphyloccocus aureus dan Escherichia coli Sony , Suyefri; Rahayu, Yayuk Putri; Nasution , Haris Munandar; Rani, Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.885

Abstract

Background: Infectious diseases caused by bacteria such as Escherichia coli and Staphylococcus aureus have become a global health issue. Matoa leaves (Pometia pinnata) are known to contain antibacterial compounds that hold potential as alternative treatments. Objective: This study aimed to produce nanoparticles from the ethanol extract of matoa leaves and compare the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values of both the extract and its nanoparticles against Escherichia coli and Staphylococcus aureus. Methods: This experimental research used different concentrations of matoa leaf ethanol extract (6.25%, 12.5%, 25%, 50%) and nanoparticle extract (0.625%, 1.25%, 2.5%, 5%). Nanoparticle characterization was performed using a Particle Size Analyzer (PSA). Results: The nanoparticle characterization showed a size of 528.95 nm. The MIC value of the matoa leaf extract against Escherichia coli and Staphylococcus aureus was 12.5%, while for the nanoparticles, it was 1.25%. The MBC value of the matoa leaf extract was 50%, and for the nanoparticles, it was 5%. The highest antibacterial activity of the ethanol extract was 18.3 mm and 18.4 mm, while for the nanoparticles, it was 18.5 mm and 19.0 mm. Conclusion: The nanoparticle extract of matoa leaves was more effective in inhibiting and killing bacteria compared to the regular extract, with a lower dose (1:10), showing its potential as an efficient antibacterial alternative.
Skrining Fitokimia dan Uji Aktivitas Antibakteri Ekstrak Etanol Dedak Padi (Oryza sativa L.) terhadap Kebocoran Membran Bakteri Staphylococcus aureus Auza , Maharani; Nasution , Haris Munandar; Pulungan , Ainil Fithri; Rani , Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.907

Abstract

Background: Rice bran is commonly utilized only as animal feed and is often regarded as a byproduct of rice milling. However, rice bran contains flavonoid compounds that exhibit antibacterial activity. This study aims to explore the potential of rice bran as an antibacterial agent, specifically against Staphylococcus aureus, through antibacterial activity testing and analysis of cell membrane leakage mechanisms. Objective: This research aims to utilize rice bran by evaluating its antibacterial activity and its mechanism of bacterial membrane leakage against Staphylococcus aureus. Methods: This experimental study involved the collection of rice bran samples, plant determination, simplicia characterization, and extraction using maceration with 96% ethanol. Phytochemical screening was conducted to identify active compounds, while antibacterial activity was tested using the disk diffusion method (Kirby-Bauer) at concentrations of 10%, 12.5%, 25%, 50%, 70%, and 80%. The membrane leakage mechanism was assessed by measuring nucleic acid and protein leakage (UV-Vis spectrophotometry) as well as Ca²⁺ and K⁺ ion release (atomic absorption spectrophotometry, AAS). Data were statistically analyzed using SPSS. Results: The ethanolic extract of rice bran yielded a 26.38% extraction yield and contained secondary metabolites, including alkaloids, flavonoids, tannins, saponins, triterpenoids/steroids, and glycosides. The antibacterial assay revealed inhibition zones classified as strong activity. Furthermore, rice bran extract induced membrane leakage in S. aureus, evidenced by increased mean absorbance values and standard deviations for DNA, protein (UV-Vis spectrophotometry), and Ca²⁺ and K⁺ ions (atomic absorption spectrophotometry) with rising extract concentrations. Conclusion: Rice bran exhibits potential as an antibacterial agent against Staphylococcus aureus through a membrane leakage mechanism. These findings support the utilization of rice bran not only as animal feed but also as a source of bioactive antimicrobial compounds.
Isolasi Gelatin dari Tulang Ikan Gulamah (Johnius trachycephalus) dan Aplikasinya Pada Permen Jelly Sindi, Sindi; Yuniarti , Rafita; Lubis , Minda Sari; Rani , Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 2 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i2.936

Abstract

Background: Gelatin, as a product of partial collagen hydrolysis, is typically derived from pig bones or skin, creating halal compliance issues for Indonesia's Muslim population. Objective: This study aimed to isolate halal gelatin from gulamah fish bones (Johnius trachycephalus) and apply it as a gelling agent in jelly candy production. Methods: The gelatin isolation process involved: (1) degreasing through immersion in boiling water, (2) demineralization using 5% acetic acid for 48 hours, (3) extraction at 60-75°C for 12 hours, and (4) oven drying at 50°C. Gelatin was characterized using FTIR and tested for quality parameters (yield, moisture content, ash content, pH) according to SNI standards. Jelly candies were formulated with two gelatin concentrations (F1=5g; F2=10g) and evaluated for physical properties and hedonic quality. Results: The study achieved a gelatin yield of 7.32% with SNI 06-3735 compliant characteristics: 10.2% moisture content, 1.24% ash content, pH 6.28, and FTIR identification of characteristic functional groups (-OH, C=O, N-H, C-H, and C-N). Formula F2 (10g gelatin) received the highest preference scores for texture (2.93), aroma (2.93), and taste (4.63). Conclusion: Gulamah fish bones show potential as a halal gelatin source meeting quality standards, with optimal application at a 10g concentration in jelly candy formulations
Uji Antibakteri Ekstrak Etanol Daun Mangga Golek (Mangifera indica L.) terhadap Bakteri Staphylococcus aureus: Antibacterial Test of Ethanol Extract of Golek Mango Leaves (Mangifera indica L.) Against Staphylococcus aureus Bacteria Yuniarti, Rafita; Rukmana, Siti; Nasution, Haris Munandar; Rani, Zulmai; Fauzi, Ziza Aisyia Putri
Jurnal Sains dan Kesehatan Vol. 7 No. 2 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i2.2427

Abstract

Mango golek is among the numerous beneficial plants in the Mangifera genus. Mango leaves have antibacterial, antifungal, antiviral, and antiparasitic properties. The purpose of this research was to determine how effective an ethanol extract of mango golek leaves was against Staphylococcus aureus bacteria and what kind of secondary metabolites were present in the extract. This study employed laboratory experimental methods such as the maceration method with 70% ethanol solvent, phytochemical screening test, and Mango golek leaf extract (Mangifera indica L.) Staphylococcus aureus antimicrobial activity test at various concentrations of 100 mg/day. mL, 70, 50, 30, and 10 mg/mL using the agar diffusion method. Mango golek leaves ethanol extract included alkaloids, flavonoids, saponins, tannins, and steroids/triterpenoids, according to the screening results. values of 100 mg/mL and 70 mg/mL were considered high, while values of 50 and 30 mg/mL were considered moderate. Keywords:          cMangifera indica L., Staphylococcus aureus   Abstrak Salah satu tanaman dari genus Mangifera adalah mangga golek yang memiliki banyak manfaat. Salah satu keuntungan adalah sifat antiparasit, antijamur, antivirus, dan antibakterinya. Tujuan penelitian ini adalah untuk mengetahui seberapa efektif ekstrak daun mangga golek terhadap Bakteri Staphylococcus aureus dan mengidentifikasi metabolit sekundernya. Dalam penelitian ini, menggunakan metode eksperimental yang meliputi uji fitokimia, pembuatan pelarut etanol 70% dari ekstrak daun mangga golek (Mangifera indica L.), dan uji antibakteri Staphylococcus aureus dengan konsentrasi 100, 70, 50, 30, dan 10 mg/mL menggunakan metode difusi agar. Hasil skrining, ekstrak etanol daun mangga golek mengandung alkaloid, flavonoid, saponin, tanin, dan steroid/triterpenoid. Uji antibakteri, ekstrak daun mangga golek memiliki sifat antimikroba Staphylococcus aureus dengan kategori kuat 100 dan 70 mg/mL dan kategori sedang 50 dan 30 mg/mL. Kata Kunci:         Antibakteri, Mangifera indica L, Staphylococcus aureus
Simplicia Characteristics and Phytochemical Screening of Buni Fruit (Antidesma bunius L. Spreng) Ningtias, Anggitha; Rani, Zulmai
Indonesian Journal of Science and Pharmacy Vol. 1 No. 1 (2023): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i1.13

Abstract

ABSTRACT Buni fruit is a plant that produces secondary and antibacterial metabolites. The purpose of this study was to identify the characteristics of the berry simplicia and the content of phytochemical compounds in the berry fruit. Starting with the maceration method using 96% ethanol, this study carried out phytochemical screening and characterization tests. The results of the phytochemical screening study showed that compounds such as flavonoids, tannins, saponins, alkaloids, and steroids were found in the ethanol extract of buni fruit. Due to the simplicia characterization, we found a water content of 9.3%, a water-soluble extract of 11.51%, an ethanol-soluble extract of 17.19%, a total ash content of 8.1%, and an acid-insoluble ash content (0.7 %).        
Characterization and Phytochemical Screening Of Tampala Bajakah Wood (Spatholobus littoralis Hassk) Extract With Methanol and Ethyl Acetate Solvents Alviana, Liya; Ridwanto, Ridwanto; Daulay, Anny Sartika; Rani, Zulmai
Indonesian Journal of Science and Pharmacy Vol. 1 No. 3 (2024): Indonesian Journal of Science and Pharmacy
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/ijsp.v1i3.40

Abstract

One of the plants that contains secondary metabolite compounds is Bajakah Tampala wood (Spatholobus littoralis Hassk). The aim of this research is to determine the chemical compounds contained in methanol and ethyl acetate extracts. The stages of this research include processing plant materials, making methanol and ethyl acetate extracts, characterization examinations, and phytochemical screening. Bajakah Tampala wood extract was made using the maceration method using methanol and ethyl acetate. The extract obtained was concentrated using a rotary evaporator. The characterization of Bajakah Tampala sawdust showed that the water content test was 2%, the water soluble juice content test was 7.1%, the ethanol soluble juice content test was 12.05%, the total ash content test was 3.65%. , and testing the ash content that is insoluble in acid was 0.1%. Meanwhile, the results of the phytochemical screening of Bajakah Tampala wood showed that it contained chemical compounds such as alkaloids, flavonoids, saponins, tannins, and steroids and triterpenoids.
Co-Authors A'dilah, Nur Abadi, Hafizhatul Adjelie, Tiara Adli Nuzula Rahmah Adyani Maulinda Afriati, Nelsi Afridah, Nurul Ilmi Ahmad Rasyid Ridho Alviana, Liya Amelia Kudadiri Andi Syahputra, Ricky Andjelie, Tiara Ani Sutiani Ani Sutiani Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Aprilia, Hijjatun Arifin, Khairil Fikri Arrosty, Muflizah Athaillah, Athaillah Audry Pratiwi Aulia Fitri Aulia Fitri, Aulia Auza , Maharani Azhar, Gustika Bambang Hermanto Bambang Hermanto Beby Noplya Wulandari BJ Sutrisna Chandra, Putra Dama Yanti, Fradilla Daulay, Anny S. Dea Anggreini Denny Satria Dewi, Sri Harti Dikki Miswanda Dinda Sari Utami Dwi Jati, Fatma Erma Susanti Evi Depiana Gultom Evi Depiana Gultom Fadhlah Al-Uyun Nasution Fahmi Fahmi Fajri, Fajrilda Aqilah Fauziah Erna Witular Panggabean Ferendina, Imelda Fithri Pulungan, Ainil Fitri, Nurul Fitri, Raissa Gabena Indrayani Dalimunthe Ginting, Grace Anastasia br Ginting, Ovalina Sylvia Br Ginting, Ovalina Sylvia Br. Gultom, Evi Depiana Hanafis Sastra Winata Harahap, Sumiyarni Haris Munandar Nasution Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hariyadi Dharmawan Syahputra Hasibuan , Fika Miah Sasmitha Hasibuan , Nabila Hasim Hasibuan, Zulfiana Ramadhani Hindri Syahputri Humaira, Annisa Husna, Miftahul Hutagalung, Victor H Indrayani, Gabena Inna Myesha Julia Reveny Karo Sekali, Elva Swandi Kasta Gurning Khairunnisa , Ardina Khan, Sahrani Nazwa Kiki Rawitri Kiki Rawitri Lestari, Amanda Putri Lestari, Kurnia Dwi Lilik Septiana Lilik Septiana Linda, Rosa Lubis, Asira Lubis, Minda Sari lubis, muhammad fauzan Lubis, Nurazizah M. Alfaruqi Maghfirah, Dini Mainal Furqan Malahayati Malahayati Maryanti Yuza Matondang , Fikriyah Hafni Maulana Putri, Yasinta Mira Febrina, Mira Monica Suryani Moondra Zubir Muhammad Agus Muljanto Muhammad Amin Nasution Muhammad Fauzan Lubis Muhammad Yunus Muhammad Yunus Mukti, Ridho Munandar, Verissa Nadila Indra Sepvina Nasri Nasri Nasri Nasri Nasri Nasri, Nasri Nasution, Wardah Nazuhra, Oca Nia Novranda Pertiwi Nindya Indah Damayanti Ningtias, Anggita Ningtias, Anggitha Nomi Noviani Nur Ain Thomas Nur, Hijrotun Nurdalilah, Nurdalilah Nurhayati Nurhayati Nurmazela, Virda Nursyafira, Arini Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Ovalina Sylvia Br. Ginting Paramitha, Ratih Parapat , Anjarlit Romiyuliana Br Pasar Maulim Silitonga Pertiwi, Rahma Pitaloka, Syifa Amilia Puspita, Dinda Dila Puteri, Cut Intan Annisa Putra, Andhika Dharma Putri Khairani Rahma Dona, Rahma Raissa Fitri Rambe, Robiatun Rawitri, Kiki Reza Irma Ricky Andi Syahputra Ridho, Ahmad Rasyid Ridwanto Ridwanto Ridwanto Rinda Sari, Syilvi Rinda Sari, Sylvi Ritonga , Nur Sakina Rizki, Dewi Rizki, Vitri Dea Robiatun Rambe Robiatun, Robiatun Rambe Ronapadua Musyirna Rahmah Nasution Sahara dan Emma Susanti Rukmana, Siti Sagala, Hasel Untung Bersinar Samran, Samran Sari Lubis, Winda Sari, Farida Sari, Syilvi Rinda Sari, Sylvi Rinda Sartika Daulay, Anny Savitri, Novia Herma Septiana, Lilik silalahi, zahra salsabila Sindi, Sindi Sipahutar, Rizki Anjani Siregar , Misbah Siti Anisa Siti Rahmah Siti Rahmi Ningrum Sony , Suyefri Sri Wahyuni Sri Wahyuni Suci, Nurul Sulwiyatul K Sani Supiyani, Supiyani SURBAKTI, CHRISTICA ILSANNA Syafa Nadira Ashiilah Syahputra, Ricky Andi Syarifah Nadia Syilfia Hasti Tania, Chyntia Glori Tarigan, Eni Surabini Trizaldi, Asep Urip Harahap Uswatun Nisa, Uswatun Vera Estefania Kaban Widya, Rizka Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Haryani Yuliatil Adawiyah Harahap Yuniarti , Rafita Yuniarti, Rafita Zahira Ahmad, Madani Ziza Putri Aisyia Fauzi Zulfikri Zulfikri Zulhij, Fizrya