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Fatimawali .
Universitas Sam Ratulangi
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ANALISIS GC-MS EKSTRAK METANOL DAN N-HEKSAN DARI BUNGA TELANG (Clitoria ternatea L.) Ma'ruf, Nurul Qalbiyyah; Antasionasti, Irma; Fatimawali, Fatimawali; Tallei, Trina
PHARMACON Vol 10, No 2 (2021): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.10.2021.34035

Abstract

ABSTRACT The butterfly pea flower (Clitoria ternatea L.) is a flower can grow as an ornamental plant or a wild plant with a single purple petal. This study aims to analyze the phytochemical compounds from butterfly pea flower. The method used is the extraction of dried powder of butterfly pea flowers using methanol and n-hexane solvent then analyzed using GC-MS. The analysis showed that there were 48 possible compounds detected in the methanol extract and 18 possible compounds  detected in the n-hexane extract of butterfly pea flower. The compound from the methanol extract which had the highest peak were d-Mannose, d-Glycero-d ido-heptose, and Galacto-heptulose. While the compounds from the n-hexane extract that had the highest peak were Longipinocarvone, Acetic acid, 3-hydroxy-6-isopropenyl-4,8a-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-2 -yl ester, and 10-12-Pentacosadiynoic acid. Keywords         : Clitoria ternatea L, butterfly pea flower, GC-MS   ABSTRAK Bunga Telang (Clitoria ternatea L.) merupakan bunga yang dapat tumbuh sebagai tanaman hias maupun tanaman liar dengan kelopak tunggal berwarna ungu. Penelitian ini bertujuan untuk menganalisis senyawa fitokimia dari bunga Telang. Metode yang digunakan yaitu ekstraksi serbuk kering bunga Telang menggunakan pelarut metanol dan n-heksan kemudian dianalisis menggunakan GC-MS. Hasil analisis menunjukkan bahwa terdapat 48 kemungkinan senyawa yang terdeteksi dalam ekstrak metanol dan 18 kemungkinan senyawa yang terdeteksi dalam ekstrak n-heksan bunga Telang. Senyawa dari ekstrak metanol yang memiliki puncak tertinggi yaitu d-Mannose, d-Glycero-d ido- heptose, dan Galacto-heptulose. Sedangkan senyawa dari ekstrak n-heksan yang memiliki puncak tertinggi yaitu Longipinocarvone, Acetic acid, 3-hydroxy-6-isopropenyl-4,8a-dimethyl-1,2,3,5,6,7,8,8a-octahydronaphthalen-2-yl ester, dan 10-12-Pentacosadiynoic acid.Kata kunci      : Clitoria ternatea L, kembang Telang, GC-MS
EVALUASI KELENGKAPAN ADMINISTRATIF RESEP DARI DOKTER SPESIALIS ANAK PADA TIGA APOTEK DI KOTA MANADO Mamarimbing, Marina; Fatimawali,, Fatimawali; Bodhi, Widdhi
PHARMACON Vol 1, No 2 (2012)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.1.2012.485

Abstract

Prescription can reduce the administrative / prevent dangerous medication errors, withadverse effects on patients by the drugs used during the management of health care. This studyis aimed to evaluate the administrative prescriptions by examining the possibility of medicationerrors by a Pediatricians at three pharmacies in the city of Manado. This is a descriptive studyconducted a retrospective review of patient prescriptions. The method of sampling took randomreceipts using the Slovin formula. 12,225 receipts was vised in the three pharmacy and found338 sheets sample of prescription from period of January to December 2011 then processed andevaluated administrative completeness. Administrative completeness prescription written by apediatrician at the Manado City Permit Practice (11.37%), Address patients (53.7%), Gender(0%), weight loss (27.5%), Age (78 , 3%), date prescription (98.4%) and to mark the R /, DoctorName, Address Doctor, Initials Doctor, Patient Name, Drug Name, Dosage, Number of Drugs,How to use a clear (100%). From these data we can conclude the potential occurrence ofmedication errors and can not find any recipes that meet the screening criteria for theprescription paperwork based on the Decree of the Minister of Healthno.:1027/MENKES/SK/1X/2004.Keywords: Administrative Complete Receipts, Receipts Pediatrician, Medication Error
TINJAUAN PENGGUNAAN ANTIPSIKOTIK PADA PENGOBATAN SKIZOFRENIA DI RUMAH SAKIT PROF. DR. V. L. RATUMBUYSANG MANADO PERIODE JANUARI 2013-MARET 2013 Jarut, Yulia Maria; Fatimawali, Fatimawali; Wiyono, Weny I
PHARMACON Vol 2, No 3 (2013): pharmacon
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.2.2013.2378

Abstract

ABSTRACTSchizophrenia is one of psychiatric disorders that caused by brain damage. The prevalence ofSchizophrenia patients in North Sulawesi were 2,4%. One way of Schizophrenia handling isgiving antipsychotics to prevent the symptoms. The aim of this research is to analyze the useof Antipsychotics on Schizophrenia patient which treated at Ratumbuysang Manado Hospital.This research is survey description research with data sampling by retrospective. Thisresearch were conducted to 142 medical records of patients period January 2013 to March2013 which receive Antipsychotics medication. Data were analyzed by univariate analysis(descriptive). Obtained data shows that the most single therapy of Antipsychotics isrisperidon (21,1%), and combined therapy was haloperidol and chlorpromazine (23,2%). Themost treatment category of Schizophrenia is the typical antipsychotic treatment (41,5%).Keywords : Schizophrenia, Antipsychotics, brain damage
Bacterial Cell Wall Synthesis Inhibition Of Clerodendrum Squamatum Vahl. Phytoconstituents: A Molecular Insight Marko Jeremia Kalalo; Elly Juliana Suoth; Irma Antasionasti; Sri Sudewi; Billy Johnson Kepe; Fatimawali Fatimawali
Jurnal Farmasi (Journal of Pharmacy) Vol 2, No 1 (2021): PROCEEDINGS ICHC
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v2i1.159

Abstract

Bacterial Cell Wall (BCW) is an essential part of bacteria. Defects in BCW may lead to bacterial death due to failure in maintaining pressure and cell integrity or shape. Penicillin-Binding Protein (PBP) 2a, 1, 2, 3, and 4 are proteins responsible for Methicillin-Resistant Staphylococcus aureus (MRSA) cell wall synthesis. MRSA is a hard-to-treat bacteria due to its antibiotic resistance. Clerodendrum squamatum Vahl. leaves (CSVL) are used by North Sulawesi-Indonesian people as a medicinal plant to treat inflammation and to heal wounds. So, the present study aims to explore CSVL potential as inhibitors of MRSA cell wall synthesis using in silico approach. CSVL phytoconstituents were analyzed using Gas Chromatography-Mass Spectroscopy (GC- MS), and the chemical structures were retrieved from PubChem and docked to PBP2a, PBP1, PBP2, PBP3, and PBP4 using Pyrx-Vina. The toxicity profile of the phytoconstituents was also calculated. The results showed that CSVL interacts with PBPs with a variety of types of bonding, dominated by hydrogen bonds. The toxicity prediction showed that CSVL has a safe toxicity profile. CSVL can be a good anti-MRSA candidate due to its molecular interactions with BCW synthesis proteins.Keywords: MRSA, antibiotic resistance, medicinal plant, PBPs 
IDENTIFICATION OF X GENE MUTATIONS, GENOTYPE AND SUBGENOTYPE OF HEPATITIS B VIRUS (HBV) Fatimawali .; Billy Kepel; Sitti Romlah; Catur Riany; Debbie Retnoningrum
Indonesian Journal of Pharmacy Vol 25 No 4, 2014
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (882.56 KB) | DOI: 10.14499/indonesianjpharm25iss4pp270

Abstract

Infection of hepatitis B virus (HBV) is a global health problem, including in Indonesia. There are currently an estimated 2 billion people worldwide are infected with HBV, about 75% of them are in Asia and 350 million of them will develop into chronic hepatitis B. Factors that influence the development of chronic hepatitis B into liver carcinoma include x gene mutation, HBV genotype and subgenotype. This research aims to identify x gene mutation, genotype and subgenotype of HBV infecting hepatitis B patients in Manado associated with the onset of liver carcinoma. HBV DNAs were isolated from blood samples of 30 hepatitis B patients. X gen was amplified using nested PCR with pre-designed primer pairs. Amplified DNA fragments were electrophoresed in 1.5% agarose and visualized under UV. DNA fragments were then separated and purified using Qiagen column, then sequenced to determine their nucleotide sequences of x gene. Amino acid of x protein were deduced from nucleotide sequence of x gene and used as basic to determine HBV genotype and subgenotype. X protein was aligned with those similar protein with the same subgenotype retrieved from GenBank to determine if there was a mutation at amino acid.  The mutated x protein were compared with other mutation found in x protein in other literatures associated with the onset of liver carcinoma. Genotype and subgenotype of HBV isolated from blood samples of 10 patients was detected and showed that five patients were infected with B genotype HBV (2 patients were infected with B2 subgenotype, 2 patients with B3 subgenotype and 1 patient with B9 subgenotype). The rest of 5 patients were infected with C genotype HBV (1 patient with C1 subgenotype, 2 patients with C2 subgenotype,  and 2 patients with C5 subgenotype). The mutation in x protein is related significantly to the clinical severity of the liver and hepatocellular  carcinoma (HCC), ie V5L in subgenotype C2, and I127T and H94Y in subgenotype C5.
Antibacterial activity of betel (Piper betle L.) fruit against Pseudomonas aeruginosa Annisa Hamka; Fatimawali Fatimawali; Olvie Syenni Datu; Trina Ekawati Tallei
Acta Biochimica Indonesiana Vol. 4 No. 1 (2021): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.10

Abstract

Background: Betel (Piper betle L.) is a well-known medicinal plant for its numerous health benefits. Saponins, flavonoids, polyphenols, and essential oils are among the chemical constituents of betel plants. Flavonoids are one of the most common groups of secondary metabolites found in plant tissues, including in betel plants. Objective: The purpose of this research is to isolate flavonoids from betel fruit and to determine the antibacterial activity of betel fruit extract against Pseudomonas aeruginosa. Methods: Thin-layer chromatography (TLC) with the eluent chloroform: methanol: water was used to isolate flavonoids. UV-Vis spectrophotometry was used to determine the presence of flavonoids in betel fruit. The antibacterial activity of extract and TLC-isolates of betel fruit was tested by using the disc method. Results: TLC analysis resulted in the formation of a brown stain. The UV-Vis spectrophotometry results revealed two absorption bands at 366 nm and 268 nm, indicating that flavonoids are present in betel fruit. Antibacterial activity test against Pseudomonas aeruginosa bacteria showed that the concentration of 30% and 60% of betel fruit extract had strong antibacterial activity. Conclusion: The results revealed that the betel fruit contains flavonoid compounds, and the extract has medium to strong antibacterial activity.
Hubungan antara Health Belief Model dengan Kepatuhan Penggunaan APD pada Perawat Morgen Ekaputra Pangaila; Fatimawali Fatimawali; Wulan Kaunang
Jurnal Kesehatan Medika Saintika Vol 12, No 2 (2021): Desember 2021
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jkms.v12i2.1100

Abstract

Penggunaan Alat Pelindung Diri (APD) dalam hirarki pengendalian bahaya merupakan pilihan untuk mencegah terjadinya kecelakaan kerja dan penyakit akibat kerja. Penelitian ini bertujuan untuk menganalisa hubungan antara konstruk Health Belief Model dengan kepatuhan penggunaan APD pada perawat. Desain penelitian yang digunakan adalah observasional analitik dengan pendekatan cross sectional. Populasi berjumlah 140 orang. Jumlah sampel 70 perawat diambil dengan menggunakan purposive sampling. Metode pengumpulan data dilakukan menggunakan kuesioner yang dibagikan melalui google form. Analisis data penelitian ini menggunakan analisis univariat, analisis bivariat dengan menggunakan uji chi square dan analisis multivariat dengan menggunakan regresi logistik. Dari hasil uji chi square didapati hasil persepsi kerentanan p=0,078, persepsi keparahan p=0,014, persepsi manfaat p=0,181, persepsi hambatan p=0,555, efikasi diri p=0,002 dan stimulus untuk bertindak p=0,002. Untuk hasil uji regresi logistik didapati hasil variabel stimulus untuk bertindak memiliki OR paling besar yaitu 2,465. Kesimpulan dalam penelitian ini yaitu, variabel yang memiliki hubungan yang signifikan yaitu persepsi keparahan, efikasi diri dan stimulus untuk bertindak, sedangkan variabel yang tidak memiliki hubungan yang signifikan yaitu persepsi kerentanan, persepsi manfaat dan persepsi hambatan. Variabel independen yang memiliki pengaruh paling besar yaitu stimulus untuk bertindak. Pimpinan rumah sakit diharapkan selalu mengingatkan tentang aturan penggunaan APD di kalangan para perawat.
Hubungan Aktivitas Fisik Dan Kualitas Tidur Dengan Kualitas Hidup Siswa Sekolah (Studi pada Siswa SMP dan SMA Di Kota Tomohon) Frans S. M. Mintardjo; Eva M. Mantjoro; Fatimawali Fatimawali; Aaltje E. Manampiring
Jurnal Pendidikan dan Konseling (JPDK) Vol. 4 No. 3 (2022): Jurnal Pendidikan dan Konseling
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.331 KB) | DOI: 10.31004/jpdk.v4i3.4715

Abstract

Kualitas hidup kesehatan merupakan salah satu kriteria yang digunakan untuk mengevaluasi intervensi pelayanan kesehatan dan dapat dipengaruhi oleh banyak faktor. Penelitian ini bertujuan untuk menilai hubungan antara aktifitas fisik dan kualitas tidur dengan kualitas hidup kesehatan remaja di Kota Tomohon. Penelitian ini merupakan penelitian korelasional dengan pendekatan cross-sectional yang diilakukan di SMP dan SMA Kota Tomohon pada bulan Oktober sampai November 2021 dengan jumlah sampel sebanyak 436 responden. Instrumen dalam penelitian ini ialah kuesioner World Health Organization-Quality of Life questionnaire (WHO-QOL), Global School-based Student Health Survey (GSHS), dan Pittsburg Sleep Quality Index (PSQI). Berdasarkan penelitian, didapatkan bahwa aktifitas fisik berupa hari aktif per minggu memiliki korelasi positif yang amat signifikan (p<0.01) dengan keempat domain kualitas hidup kesehatan remaja, yang berarti semakin tinggi aktifitas fisik, semakin tinggi pula kualitas hidup kesehatan pada remaja di Tomohon. Selanjutnya, gangguan tidur memiliki korelasi negatif yang amat signifikan (p<0.01) dengan keempat domain kualitas hidup kesehatan remaja, yang berarti semakin tinggi kualitas tidur, semakin tinggi pula kualitas hidup kesehatan. Terdapat hubungan antara aktifitas fisik dan kualitas tidur dengan kualitas hidup kesehatan remaja di Kota Tomohon.
Evaluasi Manajemen Pelayanan Kefarmasian, berdasarkan Peraturan Menteri Kesehatan RI No. 72 Tahun 2016 di Hospital Nacional Guido Valadares Dili Timor Leste Apolonia Amelintje Gusmão Awoah; Aaltje Ellen Manampiring; Fatimawali
HEALTH CARE : JURNAL KESEHATAN Vol 11 No 1 (2022): Health Care : Jurnal Kesehatan
Publisher : STIKes Payung Negeri Pekanbaru

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36763/healthcare.v11i1.228

Abstract

Pendahuluan: Hospital Nacional Guido Valadares (HNGV) Dili adalah institusi pelayanan kesehatan milik Pemerintah Timor Leste yang menyelenggarakan pelayanan kesehatan perorangan secara paripurna. Salah satu permasalahan yang memberi pengaruh terhadap kualitas layanan Hospital Nacional Guido Valadres yaitu permasalahan manajemen pelayanan kefarmasian. Tujuan penelitian ini yaitu untuk mengevaluasi manajemen pelayanan kefarmasian di HNGV Dili berdasarkan Permenkes RI No. 72 tahun 2016. Metode: Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus. Penelitian ini dilaksanakan pada Februari-April 2022 di Instalasi Farmasi Hospital Nacional Guido Valadares (HNGV) Dili. Informan penelitian sebanyak 4 orang yang terdiri dari Kepala Instalasi Farmasi Rumah Sakit (IFRS) (informan kunci), 1 orang pimpinan rumah sakit yang membawahi IFRS dan 2 orang petugas di IFRS. Instrumen penelitian ini yaitu pedoman wawancara, alat tulis menulis dan kamera. Data diperoleh dengan wawancara mendalam. Data yang diperoleh kemudian dianalisis dengan metode analisis isi. Hasil: Hasil penelitian ini menjelaskan bahwa Instalasi Farmasi Hospital Nacional Guido Valadares memiliki sumber daya manusia (SDM) sebanyak 27 orang, setiap pekerja memiliki tugas dan tanggung yang pembagiannya dilakukan oleh kepala IFRS, beban kerja masih perlu dikaji secara lanjut serta gaji pegawai sudah sesuai standar yang ada. Pada tahapan ini ditemukan adanya masalah yaitu adanya kekurangan SDM di IFRS sehingga tugas dan tanggung jawab sering terabaikan saat ada pekerja yang tidak masuk kerja. Instalasi Farmasi Hospital Nacional Guido Valadares melakukan perencanaan obat dengan metode konsumsi tapi hanya sebatas pengusulan atau permintaan melalui SAMES.IP. Ditemukan masalah dalam proses perencanaan pelayanan kefarmasian yaitu proses perencanaan khusus penganggaran dan penetapan prioritas belum bisa dilakukan oleh IFRS. Selain itu, waktu tunggu pemesanan obat masih belum dilakukan kajian karena keterbatasan metode, dana dan tenaga. Instalasi Farmasi Hospital Nacional Guido Valadares bertanggung jawab untuk penyimpanan dan pendistribusian obat. Pengadaan obat di rumah sakit menggunakan sistem terpusat. Harga, ketersediaan dan mutu obat merupakan kewenangan dari Kementerian Kesehatan melalui SAMES.IP. Instalasi Farmasi Hospital Nacional Guido Valadares sudah berusaha melakukan pelayanan pendistribusian yang menjamin mutu, stabilitas, jenis, jumlah, dan ketepatan waktu. Selain itu, sistem distribusi di unit pelayanan IFRS menggunakan sistem resep individu dan sistem kombinasi antara individu dan floor stock. Kesimpulan: Kesimpulan penelitian ini yaitu manajemen pelayanan kefarmasian di HNGV Dili berdasarkan Permenkes RI No. 72 tahun 2016 telah berjalan namun masih ditemukan beberapa masalah dalam pelaksanaannya.
ISOLASI DAN IDENTIFIKASI BAKTERI RESISTEN MERKURI DARI MUARA SUNGAI SARIO YANG DAPAT DIGUNAKAN UNTUK DETOKSIFIKASI LIMBAH MERKURI Fatimawali Fatimawali; Fatmawaty Badaruddin; Irawan Yusuf
JURNAL ILMIAH SAINS Volume 11 Nomor 2, Oktober 2011
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (301.332 KB) | DOI: 10.35799/jis.11.2.2011.220

Abstract

ISOLASI DAN IDENTIFIKASI BAKTERI RESISTEN MERKURI DARI MUARA SUNGAI SARIO YANG DAPAT DIGUNAKAN UNTUK DETOKSIFIKASI LIMBAH MERKURI Fatimawali1), Fatmawaty Badaruddin2), Irawan Yusuf 2) 1)Dosen Fakultas  Kedokteran Unsrat Manado dan Mahasiswa Program Doktor Fakultas Kedokteran Universitas Hasanuddin Makassar; 2)Dosen Fakultas Kedokteran Universitas Hasanuddin Makassar ABSTRAK Merkuri adalah logam berat yang bersifat sangat toksik, mempunyai afinitas terhadap gugus thiol protein.  Keberadaan merkuri  dilingkungan, karena secara alamiah maupun karena aktifitas antrofogenik. Di Kabupaten Bolaang Mongondow terdapat beberapa penambang emas rakyat yang menggunakan merkuri untuk mengekstrak emas dari batuan atau ore dan membuang limbah merkuri secara bebas ke lingkungan dan terbawa air hujan sampai kepada perairan.  Sedimen perairan yang terkontaminasi merkuri dapat ditumbuhi bakteri resisten merkuri.  Bakteri resisten merkuri anorhanik dapat digunakan untuk bioremediasi perairan, karena bakteri tersebut mampu mereduksi merkuri anorganik menjadi logam merkuri yang mudah menguap dan kurangtoksik.  Dan merupakan sumber pencemaran merkuri.  Bakteri resisten merkuri mempunyai operon mer yang biasanya terkandung dalam plasmid.  Penelitian ini bertujuan untuk mengisolasi bakteri resisten merkuri anorganik, dan menganalisis kemampuannya dalam mereduksi HgCl2 dalam media nutrient broth.  Bakteri resisten merkuri tinggi, dilakukan analisis Gen 16S rRNAnya untuk mengetahuis pesiesnya.  Hasil penelitian menunjukkan bahwa isolat A1.1.1 merupakan bakteri spesies Klebsiella pneumoniae, mampu mereduksi HgCl2 75% dalam waktu 1 jam, 92% dalam waktu 12 jam dan 99,4%  dalam waktu 24 jam Kata Kunci: bakteri, detoksifikasi,  HgCl2,  Klebsiella pneumoniae   ISOLATION  AND  IDENTIFICATION OF MERCURY-RESISTANT BACTERIUM FROM SARIO RIVER ESTUARY THAT CAN BE USED TO DETOXIFY INORGANIK MERCURY WASTES ABSTRACT Mercury (Hg) is well known for its high toxicity and strong affinity toward the thiol group of proteins. When Hg released into the environment in substantial quantities through natural events and anthropogenic activities . In District of Bolaang Mongondow, many miners who are a source of mercury pollution of aquatic environments to which they use to extract gold from the rock or ore. Waters sediment contaminated with mercury, can be overgrown with microorganism such as bacteria that are resistant to mercury.  Mercury-resistant bacteria can be used for bioremediation of waters due to the ability of these bacteria to reduce toxic inorganic mercury into mercury metal which is volatile and less toxic. Mercury-resistant bacteria has mer Operon which usually contained in the plasmid.  The aim of this study was the selection of bacterial strains resistant to inorganic mercury, as well as to show their capacity to reduce mercury  in pure culture media Nutrient Broth. Twelve isolate bacteria was selected for its capacity to reduce mercury HgCl2 in culture media nutrient broth. The one bacterial strains belong to the spesies Klebsiella pneumoniae. Inoculated in pure culture, these strain showed a mercury reduction of 75% in 1 hour, 92% in 12 hours, and  99,4% in 24 hours. Keywords : bacteria , detoxification, HgCl2 ,  Klebsiella pneumoniae
Co-Authors Aaltje E. Manampiring Aaltje E. Manampiring Aaltje E. Manampiring Aaltje Ellen Manampiring Aaltje Manampiring Aaltje Manampiring Aaltje Manampiring Aaltje Manampiring Abas, Abdul Hawil Abdul Jalil Abubakar, Poetry M.S. Abubakar, Poetry Melinda Achmad, Mardhita Nilamsari Adeanne Wullur Adikila, Gregorius Giani Adithya Yudistira Adrian Umboh Ahmad Haekal Alamri, Firdaus Alexander S. L. Bolang Andini Andrew Pangemanan, Andrew Angelina Stevany Regina Masengi Angelique Baya, Gloria Prisca Susana Angelique C. M. Tanan Anggelia Nelisa Kapantow Anita Linda Yohana Pratasik Anita Mamuaya Anita Rahel Meilina Paendong Anjely Jessica Makatempuge Annisa Hamka Antasionasti, Irma Apolonia Amelintje Gusmão Awoah Asriyana S Kaseng Astrid Noviera Iksan Axl L. Windah Ayu Fauzia Malinda B H. R. Kairupan Baharuddin, Fatmawaty Bahter, Julia V.F. Barasarathi , Jayanthi Basalamah, Rizqah BEIVY JONATHAN KOLONDAM Bernadus, Zefanya Bernadus, Zefanya G Billy J Kepel Billy J Kepel Billy J. Kepel Billy J. Kepel Billy Johnson Kepe Billy Kepel Billy Kepel Billy Kepel Bodhi , Widdhi Budiarso, Fona Hermina Dwiana Budiarso, Fone D.H. Budiarso, Hermina Butue, Leobernard Catur Riany Celik, Ismail Changiz Mohiyeddini Cheisy Anastasya Gratia Lengkong Chintya G. Derek Christi Diana Mambo Damaris Damaris Datu, Olvie S. Datu, Olvie Syenni Debbie Retnoningrum Debora Tandi DEBY AFRIANI MPILA Defny S. Wewengkang, Defny S. Deliyana Lanti Desye Nurmalita Tanan Devianitta Sarapi Dian Pratiwi Dina V. Rombot Dinda V. Lomotu Dolongtelide, Jeclin Inebel Donald Andreas Chandra Dos D. L. E. Br Siagian Edward Nangoy Eka Mulya Muthalib Ekawati Tallei, Trina Ellen Manampiring, Aaltje Elly Suoth Endang Triastuti Engka, Joice Nancy Ermawati Ermawati Eva M. Mantjoro Farhan A. Bidullah Fatima Fatima Fatmawaty Badaruddin Febrisa Salsabila Feti Fatimah Feybe Ireine Kumayas Fona Budiarso Frans S. M. Mintardjo Frederika Filly Toad Frenly Wehantouw Frisky S. Badi, Frisky S. Friyan Criscanus Manopo Gabriela Clementine Ranti Gani Jumaat Gani, Maria A Gani, Maria A. Gayatri Citraningtyas Gazali Gazali Gemi Nastiti Gerungan, Yizreel Y. GONI, BRIGITA CHRISTANIA AURORA Grenshannya Anasthasya Pua Greta J. P. Wahongan Gueen L. G. Naray Gustaaf A. E. Ratag Hamdiyah Hamzah Hamidah Sri Supriati Hanna Elga Sulu Hariyanto, Yuanita Amalia Hasan, Puput Herawati Hasan, Puput Herawati Said Hasanuddin, Israyati R. Hebber, Tri Heedy M Tjitrosantoso Henki Rotinsulu, Henki Hermina Budiarso, Fona Dwiana Herny E.I. Simbala Hosea Jaya Edy I Dewa Ayu Accyuta Kirana I Dewa Ayu Prabawati I Putu Andika Arianta Inda V. M. Rawung, Inda V. M. Intan Baiduri Inti Rizcy Sari Sugeha Irawan Yusuf Irawan Yusuf Irma Antasionasti Irma Antasionasti Irma Antasionasti Irma Febrianti Wahongan Irma Tristanti Iswanto Toling Jainer P Siampa Jainer Pasca Siampa Jayanto, Imam Jeane Mongi Jimmy Posangi Jimmy Posangi Jimmy Posangi Jimmy Posangi Jimmy Posangi John Socrates Kekenusa John Socrates Kekenusa Johnson Kepel, Billy Josepin P Konda Julianri Lebang Julianri Sari Lebang Julianri Sari Lebang Junita M. Pertiwi Junita Maja Pertiwi Jurike Kaunang Kairupan, Tara S. Kalalo, Marko Jeremia Kalalo, Tekla Kamaruddin Kamaruddin Kambey, Debora F. Kapondo, Gwendolyn L. Karamoy, Eunike M. Kawengian, Shirley ES. Keintjem, Brigieta Kepel, Billy Kepel, Billy Johnson Kepel, Regina E.M. Kezia Pangemanan Kissi Parengkuan Konda, Josepin P Kuliahana, Ana Kumowal, Selphina Lady zha-zha Luntungan Lampus, Christania Landy A. Ch Lolaen LAPIAN, ALDA JULISTY GABRIELA Lasut, Misella R. C. Lasut, Misella Regina Laurencia Diva Bernadette Artantyo Lengkong, Cheisy Anastasya Gratia Leonardo Delvin Gosal Ley, Gabriella Therezia Ley Lidya Togelang Lidya Valda Mamoto Lisa Kepel M. Fadhel Nurmidin Ma'ruf, Nurul Qalbiyyah Makatambah, Venila Malino, Angeline Priscillia Mambo, Christi Diana Manampiring, Aaltje Ellen Mansur, Nurfauziah Mantjoro, Eva M. Maria Immaculata Tangkau Marina Mamarimbing Marko Jeremia Kalalo Marko Jeremia Kalalo Maulydia, Nur B. Max R.J. Runtuwene Meilani Jayanti Melkianus, Brando Miranti Aike Wemay Mohtar, Khumairah Monalisa Karinda Morgen Ekaputra Pangaila Muh. Rifaldi Latarang Muharli Qadri Kanon Mutiara Cantika Mutiara Ramadani Mutmainah Mutmainah Nainggolan, Ivana C. Natasya Ester Rebeca Tamahiwu Natsir, Rosdiana Ni Wayan Dianti Niode, Nurdjannah Jane Nova Hellen Kapantow Novelina Irianti Damanik Nurdjannah J. Niode Nurfitriani Nurfitriani, Nurfitriani Nurhamidin, Anastasia P.R. Oksfriani Jufri Sumampouw Olivia C. Mulalinda Olivia G. Mokolensang, Olivia G. Olvie Datu Olvie Syenni Datu Olvie Syenni Datu Olvie Syennie Datu Omega Agral Owu, Nadya M. PANI, PUTRI MARGARETHA GLAUDY Pantow, Natalia M. Patrick Muljono Patrick Muljono, Patrick Paukiran, Degol Paulina Yamlean Paulina yamlean Paulina Yamlean Pehino, Albrita Pendong, Christa Hana Angle Poluakan, Ricko Johanes Prasetio, Nathanael F. Prayoga, Deshanda Kurniawan Puasa, Novanda S. Purwanto, Diana Shintawati Putri, Ida A. R. Putri, Prisna Aswarita Rahmad Dian Rambi, Christani I J Ratte, Titah Amelia Ratu, Belinda D. P. M. Ratulangi, Andrew Johanes Refa Riski Aulia Rengur, Zul Aini Rifky Aditya Rahadian Rifqi Adithya Rika Wulandari Rimporok, Aprilia Rinaldi Idroes RINI Rio Windy Sondakh Ristanti Pratiwi Rizya Marchilia Mamahit Rotinsulu, Sarah Rotty, Linda WA. RUMALUTUR, CHRISTHALIA IEWANDA Rumangu, Chrisa P. Rumondor, Erladys M. Rundengan, Gerald Sahi, Makbul Renaldi Saragih, Nathin Loria , Sarah Mariana Pattuju Saranita V. G. Polii sari sakinah Sherly Dawile Shintia, Arini Siampa, Jainer P Siampa, Jainer Pasca Siboantua Broolin Simanjuntak Siringo-Ringo, Aurian Fricilia Siti Suhartini Sitti Romlah Sri Sudewi Sri Sudewi, Sri Sriwaningsih S Nahe Stevana F.A. Paat Sumakul, Gilbert Samuel Sumual, Acika Surya, Welong S. Syifa Katili Talla, Tamrin Tallei, Trina Ekawati Tania, Adinda Dwi Tendean, Lydia Estelina Naomi Terence Kanzil Titah Amelia Ratte Tjandra A. Rumagit Tjandra, Regina F. Trina E Tallei Trina E Tallei Trina E. Tallei, Trina E. TRINA EKAWATI TALLEI Trina Ekawati Tallei Trina Ekawati Tallei Trina Tallei Trina Tallei Trina Tallei Turalaki, Grace Lendawati Amelia Vanessa J. T. Seran, Vanessa J. T. Vibrila Berliana Djanas Watania, Marcela Wawo, Arsianita Ester Welong S. Surya Welong S. Surya Welong S. Surya Weny I Wiyono Weny Wiyono Wewengkang, Defny Widdhi Bodhi Widdhi Bodhi Widdhi Bodhi Widdhi Bodhi widdhi Bodhi Widdhi Bodhi Widhi Bodhi Widya Hana Putri Gerung Wijaya, Puspita Windy Sumarauw Wulan P. J. Kaunang Wulan Palilingan, Wulan Wulan Tuerah Wungouw, Herlina Ineke Surjane Wungouw, Herlina IS. Yohanes Adithya Koirewoa Yulia Maria Jarut Yulianty Sanggelorang Yuyun Andriani Agus Zahra Zahra Zainal Abidin Zulfikri Zulfikri, Zulfikri