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Skrining fitokimia dan uji aktivitas antibakteri ekstrak etanol daun kayu Jawa ((Lannea coromandelica) (Houtt) Merr terhadap bakteri Propionibacterium acnes dan Staphylococcus epidermidis Munaziatul Jannah; Haris Munandar Nasution; M. Pandapotan Nasution; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.241

Abstract

Jawa wood (Lannea coromandelica) (Houtt.) Merr. is a tropical plant that has potential as a medicinal plant. Almost all parts of this plant can be used in traditional medicine. This wild plant can be found easily in various locations such as home gardens, roadsides and community gardens. This study aims to evaluate the potential antibacterial activity of ethanol extract from the leaves of Kayu Jawa (Lannea coromandelica) (Houtt.) Merr. Against the growth of Propionibacterium acnes and Staphylococcus epidermidis bacteria. This research used experimental methods involving sample collection, macroscopic examination, microscopic examination, simplicia making, characteristic examination, Phytochemical Screening, and Antibacterial Activity Test using ethanol extract from Kayu Jawa ((Lannea coromandelica) (Houtt) Merr) against the bacteria Propionibacterium acnes and Staphylococcus epidermidis, using the agar diffusion method. Macroscopic examination results show that the leaves of Kayu Jawa have a tapered shape with a total of 7-11 strands. The flowers produced are single and yellowish-green in color, while the fruit has seeds of a certain length. Microscopic examination reveals the upper epidermis, palisade fragments, coral flowers, and wooden vessels with thickened spirals and stairs. The characteristics of simplicia show a water content of 4%, soluble essence content in water 21%, soluble essence content in ethanol 23%, total ash content of 4.8%, and insoluble ash content of 0.4% acid. The results of phytochemical screening on simplicia powder and ethanol extract of Kayu Jawa leaves showed contents such as alkaloids, tannins, flavonoids, steroids/triterpenoids, saponins and glycosides. The antibacterial activity test showed that Jawa wood showed potential as an antibacterial agent, with different inhibitory abilities depending on the concentration used. At a concentration of 20%, an inhibition zone of 6.85 mm was observed against Propionibacterium acnes and 5.75 mm against Staphylococcus epidermidis. Meanwhile, at a concentration of 80%, the area of inhibition increased to 14.15 mm against Propionibacterium acnes and 11.75 mm against Staphylococcus epidermidis.
Uji aktivitas antibakteri ekstrak etanol asam sunti terhadap bakteri Streptococcus mutans Novika Utami; Haris Munandar Nasution; Rafita Yuniari; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.286

Abstract

Asam sunti is belimbing wuluh, which is processed into a special food additive from Aceh Province because it becomes dregs and interferes. Belimbing is processed into asam sunti for seasoning or additional dishes. Belimbing contains active compounds such as alkaloids, triterpenoids, saponins, tannins, and flavonoids. Because Belimbing has an antibacterial pharmacological effect, it has been shown to fight bacteria that cause dental caries. The main cause of dental caries is the activity of Streptococcus mutans bacteria. The researcher took the research problem regarding the test of the inhibitory power of asam sunti extract. They know the antibacterial activity of 96% ethanol extract. The method used in this study was an experimental method with independent variables, namely asam sunti simplicia and asam sunti concentration. The main variables were the secondary characteristics and the metabolite content of the asam sunti ethanol extract. The tests included inhibiting asam sunti's ethanol extract against bacteria. The results of plant identification showed that the antibacterial inhibition zone of the ethanol extract of asam sunti belimbing wuluh ethanol extract with a concentration of 20% (18.54) mm, 40% (20.79) mm, and concentration of 60% (21.48) mm including Thus is known that the concentration of ethanol extract of asam sunti Belimbing wuluh on 20%-60% is an effective concentration to inhibit Streptococcus mutans bacteria The concentration of the ethanol extract has very strong antibacterial powder, causing a large inhibition zone.
Skrining fitokimia dan isolasi senyawa flavonoid dari ekstrak etanol kulit buah menteng (Baccaurea racemosa (Reinw.) Müll.Arg) Muhammad Ari Mukhtizar; Haris Munandar Nasution; M. Pandapotan Nasution; Rafita Yuniarti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.299

Abstract

The menteng plant, which belongs to the Euphorbiaceae family, is a subtropical plant worldwide. Flavonoids are one of the groups of phenolic compounds found in plant tissues that can act as antioxidants. This research aimed to determine the class of chemical compounds found in the Menteng fruit peel and determine the characteristics of fruit peel flavonoids by UV Spectrophotometry and IR Spectrophotometry. %. Phytochemical screening showed positive for alkaloids, flavonoids, and steroids/triterpenoids, while tannins, saponins, and glycosides were negative from 400 grams of simplisia produced 39.1 grams of viscous extract. Characterization of crystal isolates of UV spectrophotometry showed a wavelength of 280 nm, inferred to be a flavanoid. The results of IR spectrophotometry show the O-H, C-H aliphatic, C=C aromatic, C=O, C-H, and C-O groups.
Penetapan kadar fenolik total ekstrak kayu bajakah (Spatholobus littolaris Hassk.) berdasarkan perbedaan konsentrasi etanol dengan metode spektrofotometri Uv-Vis Indah Triutami Harahap; Anny Sartika Daulay; Fathur Rahman; Haris Munandar Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.302

Abstract

The root of the Bajakah tampala (Spatholobus littolaris Hassk.) is one of the plants that is empirically used by the people of the interior of Central Kalimantan as a traditional medicine. According to the preliminary tests conducted, Bajakah Tampala contains phenolics. Phenolic compounds are compounds that have antioxidant activity. The objective of this research was to determine the class of compounds contained in the macerated extract and the total phenolic content and yield of the macerated extract in Bajakah roots. The stages of this research included the processing of plant materials, preparation of macerated and pirated root extracts, characterization examination, phytochemical screening, and the effect on the yield of total phenolic content of Bajakah roots using the UV-Vis spectrophotometry method. The results showed that the simplicia powder of the root of the Bajakah wood contained alkaloids, glycosides, steroids and triterpenoids, flavonoids, phenolics, saponins, and tannins, while the ethanol extract of the roots of the Bajakah wood showed the presence of alkaloids, steroids and triterpenoids, tannins, saponins, flavonoids, and phenolic compounds. The determination of total phenolic content was carried out by determining the maximum wavelength of gallic acid and calculating the total phenolic content based on the difference in ethanol concentration using the UV-Vis spectrophotometry method. The results for determining total phenolic content in 96% ethanol extract were 33.872 ± 0.0420 mg GAE/g, 70% ethanol extract was 29.345 ± 0.2149 mg GAE/g, and 50% ethanol extract was 18.512 ± 0.1355 mg GAE/g. So it can be concluded that the total phenolic content of 96% ethanol extract is higher than that of 70% ethanol extract and 50% ethanol extract.
Skrining fitokimia dan isolasi senyawa flavonoid dari ekstrak etanol biji buah menteng (Baccaurea racemosa (Reinw.) Müll.Arg). Sarmadansyah Sarmadansyah; Haris Munandar Nasution; Anny Sartika Daulay; Daeng Elysa Putri Mambang
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.304

Abstract

Menteng or kepundung is a fruit-producing tree. At first glance, Menteng or kepundung fruit resembles duku fruit with a variety of tastes (sour) and sweet. Menteng originates from Malaysia, Sumatra, Java and Bali. The purpose of this study was to determine the class of chemical compounds found in Menteng fruit seeds and to determine the characteristics of the fruit seed extract isolates by UV spectrophotometry and IR spectrophotometry. This research includes several processes, namely manufacturing simplicia from menteng fruit seeds, phytochemical screening, and simplicia characterisation. The process of making extracts from menteng fruit seed Simplicia, after that extract analysis using paper chromatography (KKt) method, then separation (isolation) of the extract with preparative paper chromatography (KKt) method, tested the purity of isolates by two-way paper chromatography (KKt), and characterisation of isolate crystals by UV spectrophotometry and IR spectrophotometry. The results of the simplicial characterisation of Menteng fruit seeds (Baccaurea racemose (Reinw.) Müll. Arg) are 4% water content, 36.81% seawater content, 8.79% ethanol soluble extract, 1.26% ash content, 1.26% ash content. Insoluble 0.5% acid. Phytochemical screening showed positive alkaloids, flavonoids, steroids/triterpenoids and glycosides, while tannins and saponins were negative. From 400 grams of simplicia, 93.3 grams of condensed extract was produced. Characterisation of isolate crystals UV spectrophotometry showed a wavelength of 280 nm, which is suspected to be a flavonoid. The results of the IR spectrophotometry showed aliphatic O-H, C-H, C=O, C-H, C-O and C=C groups.
Skrining fitokimia dan isolasi senyawa steroid/triterpenoid dari ekstrak n-heksana daun Pepaya (Carrica papaya L) Cindy Widya Rosa Br Simarmata; Haris Munandar Nasution; M Pandapotan Nasution; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.324

Abstract

In Indonesia, papaya plants are common in several areas, from Sabang to Merauke. As a tropical country, almost all corners of Indonesia have various shapes and different types of papayas. Papaya leaves (Carica papaya L.) contain tannins, alkaloids, flavonoids, terpenoids, and saponins which act as antiparasitics. This research aims to determine the results of the chemical compound groups found in papaya leaves (Carica papaya L.). To determine the characteristics of isolates from n-hexane extract of papaya leaves (Carica papaya L.) using UV and IR spectrophotometry. This research includes making simplicia from papaya leaves, then phytochemical screening, then simplicia characterization, then making extracts from papaya leaf simplicia, after that analysis of the extract using the thin layer chromatography (TLC) method, then isolation using column chromatography (KK), purity testing using Two-way thin layer chromatography (TLC) and the isolation obtained were identified using ultraviolet (UV) spectrophotometry and infrared (IR) spectrophotometry. The results of the characterization of the Carica papaya L Simplicia showed that the water content was 4%, the water-soluble essence content was 16.64%, the ethanol-soluble essence content was 11.6%, the total ash content was 9.88%, the ash content was 0. 66%, the results of the phytochemical screening of Carica papaya L., simplicial contain steroid/triterpenoid compounds, alkaloids, flavonoids, saponins, tannins. The results of the isolated analysis showed that the isolate obtained was a violet-colored steroid/triterpenoid compound. The isolate obtained was analyzed using UV light spectrophotometry, giving an absorbance at a wavelength of 207 nm, indicating that there was a chromophore group. The IR spectrophotometry results showed OH, aliphatic CH, and CH2 groups, CH3, C=O and CO.
Skrining fitokimia dan isolasi senyawa steroid/triterpenoid dari ekstrak n-heksana biji nangka (Artocarpus heterophyllus Lam). Tawir Rina Rezeki; Haris Munandar Nasution; M Pandapotan Nasution; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.331

Abstract

Nangka (Artocarpus heterophyllus Lam) merupakan tumbuhan yang dapat berkembang dengan baik di wilayah tropis seperti Indonesia. Biji Nangka mengandung senyawa kimia jenis steroid/triterpenoid, termasuk beberapa jenis steroid yang memiliki manfaat sebagai bahan dalam obat-obatan, seperti estrogen, progestin, dan kardenolida. Penelitian bertujuan untuk melakukan pengujian secara fitokimian dan juga mengisolasi senyawa steroid/ triterpenoid biji Nangka. Penelitian ini menggunakan metode eksperimental, termasuk proses ekstraksi senyawa dengan metode maserasi dan isolasi senyawa aktif melalui kromatografi kolom. Identifikasi isolat murni dilakukan dengan menggunakan spektrofotometri UV dan spektrofotometri IR. Hasil skrining fitokimia menunjukkan keberadaan senyawa steroid/triterpenoid, glikosida, dan alkaloida dalam sampel. Isolat tersebut memiliki warna ungu dengan nilai RF 0,25, dan puncak absorbansi maksimum terletak pada panjang gelombang 208,20 nm, menunjukkan adanya gugus kromofor. Hasil spektrofotometri IR menunjukkan adanya gugus seperti OH, -CH alifatis, CH2, CH3, C=O, C-O, dan C=C. Kesimpulan dari penelitian ini adalah bahwa isolat yang diperoleh termasuk dalam golongan senyawa steroid/triterpenoid.  
SOSIALISASI PEMANFAATAN YOGURT UNTUK MENURUNKAN HIPERTENSI KEPADA MITRA PENGELOLA ZAKAT YAYASAN PENDIDIKAN AMALIYAH KECAMATAN MEDAN TEMBUNG Yayuk Putri Rahayu; Haris Munandar Nasution Nasution; Supiyani Supiyani
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 5 (2023): Volume 4 Nomor 5 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i5.21628

Abstract

Yogurt diketahui dapat menurunkan hipertensi dikarenakan dalam yogurt mengandung bakteri probiotik yang dapat mendorong pelepasan protein yang dapat menurunkan tekanan darah. Tujuan kegiatan PKM ini adalah memberikan sosialisasi pengetahuan tentang pemanfaatan yogurt untuk menurunkan hipertensi kepada Mitra Pengelola Zakat (MPZ) Yayasan Pendidikan Amaliyah kelompok forum silaturahmi Badan Kemakmuran Mesjid (BKM) Al-Hikmah kecamatan Medan Tembung. Metode yang digunakan dalam PKM ini adalah: (1) Penyuluhan (sosialisasi) ceramah pentingnya yogurt untuk menurunkan hipertensi, dan (2) Pemberian pengetahuan berbagai jenis contoh produk yogurt. Kegiatan PKM dilakukan dengan beberapa tahap: (1) Tahap survey, melakukan kerjasama dengan mitra, dan menentukan tema kegiatan; (2) Tahap persiapan PKM; (3) Tahap penyuluhan dan sosialisasi, dan penyampaian materi; dan (4) Tahap penyampaian berbagai contoh jenis produk yogurt. Hasil yang didapatkan dari kegiatan PKM ini adalah pengetahuan mitra peserta PKM tentang yogurt dapat menurunkan hipertensi meningkat menjadi 71.21% dari rata-rata nilai pengetahuan 4.40 menjadi 7.53. Kesimpulan dari kegiatan pengabdian PKM ini adalah (1) Peserta mitra menjadi mendapatkan pengetahuan tentang yogurt dapat menurunkan hipertensi, dan (2) Peserta mitra mendapatkan pengetahuan berbagai contoh jenis yogurt. Kegiatan PKM yang telah dilaksanakan dapat meningkatkan pengetahuan masyarakat sehingga dapat meningkatkan kualitas hidup dari segi kesehatan di keluarga dan masyarakat.
OPTIMASI PEMBUATAN TEPUNG TALAS TERMODIFIKASI (Modified Taro Flour) DENGAN FERMENTASI Lactobacillus casei BERDASARKAN KADAR PROTEIN Imelda Natasia Br S Meliala; Anny Sartika Daulay; Ridwanto Ridwanto; Haris Munandar Nasution
Jurnal Farmasi Klinik dan Sains Vol 3, No 1 (2023): Jurnal Farmasi Klinik dan Sains
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Muhammadiyah Gombong

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26753/jfks.v3i1.1110

Abstract

Ketergantungan penggunaan tepung terigu dapat dikurangi dengan menggunakan sumber karbohidrat lainnya seperti talas yang merupakan pangan lokal. Lactobacillus casei adalah salah satu spesies Bakteri Asam Laktat yang dapat menggunakan selobiosa sebagai sumber nutrisinya. Diperkirakan Lactobacillus casei dapat mendegresi sel umbi talas agar meningkatkan kadar protein talas. Diantara faktor yang dapat mempengaruhi kondisi fermentasi untuk menghasilkan tepung termodifikasi yang optimal adalah waktu fermentasi. Penelitian ini bertujuan untuk mengetahui pengaruh optimasi fermentasi umbi talas terhadap organoeleptis dan kadar protein pada tepung talas termodifikasi. Penelitian ini menggunakan metode eksperimental dengan dua optimasi waktu fermentasi yaitu fermentasi 48 jam dan fermentasi 72 jam dan uji karakterisasi yaitu uji organoleptis, uji kadar air, uji kadar abu dan uji kadar protein. Hasil penelitian ini menunjukkan organoleptis tepung mocaf, tepung talas, tepung talas termodifikasi berwarna coklat dan putih kecoklatan, bau sedikit asam dan tekstur yang halus. Kadar protein mocaf yaitu 2,17, tepung talas 2,33%, tepung talas termodifikasi 48 jam 3,16%, tepung talas termodifikasi 72 jam 3,53%. Kadar air tepung mocaf 11,31%, tepung talas 8,67%, tepung talas termodifikasi sebesar 10,81%. Kadar abu tepung mocaf 1,13%, tepung talas 2,73%, tepung talas termodifikasi 1,82%. Hasil yang diperoleh menunjukkan bahwa  fermentasi 72 jam merupakan hasil yang optimal.
Uji Aktivitas Antipiretik Ekstrak Etanol Daun Durian (Durio Zibethinus L.) Pada Tikus Putih Jantan (Rattus Norvegicus) Galur Wistar Riza Syafira; D Elysa Putri Mambang; Gabena Indrayani Dalimunthe; Haris Munandar Nasution
Jurnal Ilmu Kesehatan dan Gizi Vol. 1 No. 3 (2023): Juli: Jurnal Imu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v1i3.1513

Abstract

Durian leaves have secondary metabolites, namely flavonoids. Flavonoids have shown a wide range of bioactivity, one of which is an antipyretic effect which can be used as a febrifuge. This study aims to examine the antipyretic activity of the ethanol extract of durian leaves (Durio zibethinus L.) against male white rats (Rattus norvegicus) induced by DPT-HB-Hib vaccine. This study uses an experimental method. In this study, durian leaf extract was processed by maceration using 96% ethanol, then treated with secondary metabolites of simplicia and its ethanol extract. To pay for the antipyretic activity of durian leaves (Durio zibethinus L.) the test animals used were 25 and divided into 5 groups, namely negative control (CMC 0.5%), positive control (Paracetamol 1%) and the test dose group, namely the administration of leaf extract durian 200 mg/kg, 300 mg/kg and 400 mg/kg. Each rat was induced intramuscularly with the DPT-HB-Hib vaccine. Temperature measurements were carried out rectally with initial temperature measurements at 5 minute intervals 3 times, 1 hour after induction and 30 minutes for 3 hours. The data obtained were analyzed using the One-way ANOVA (Analysis of Variance) test and the Tukey HSD test. Based on the results of the study, it was shown that the results of the phytochemical screening of durian leaves contained flavonoids, saponins, tannins, alkaloids, steroids/triterpenoids. Of the three doses that experienced a decrease in temperature that was not significantly different from paracetamol, namely at a control dose of 300 mg/kg, because this decrease in temperature was almost close to paracetamol which was positive.
Co-Authors Adelia Ramadani Adjelie, Tiara Adyani Maulinda Ahmad Rasyid Ridho Ainil Fithri Pulungan Alaina, Nadila Alfi Wahyudi Nasution Amaliana, Amaliana Ananda , Nadia Andjelie, Tiara Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Anny Sartika Daulay Apmarja, Sarah Utami Aris Munandar Aryunda, Divia Asmarani, Asmarani Aulia Fitri, Aulia Aulia Sari Auza , Maharani Ayu , Tri Indah Pagar Azhar, Gustika Barutu, Liza Anisa Shevia Basaniah Basaniah Bilal, Mohd. BJ Sutrisna Cici Andriani Cindy Priscilia Cindy Widya Rosa Br Simarmata Cut Dian Mala Luthfia Cut Erika Maulydya D Elysa Putri Mambang D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang Daeng Elysa Putri Mambang Daulay , Anny Sartika Delvi Amira Hutagaol Dikki Miswanda Dina Agustia Parlin Dina Suciati Saragih Dinda Sari Utami Dini Rahmadani Dwi Jati, Fatma Ellyza, Chella Emmy Wiriandini Ercha Minanda Fahira, Nelsa Fahmi Fahmi Fathur Rahman Fatimah, Cut fatur Rahman, fatur Febiyani, Rica Fithri Pulungan, Ainil Fitri Mulyani, Fitri Fitri, Nurul Fitri, Raissa Friyani, Lilah Gabena Indrayani Dalimunthe Hafizha, Putri Hasanah, Qori Hasibuan , Nabila Hasim Hasibuan, Supia Indah Hastri Kholifah Humaira, Yara Hutagalung , Septi Ratna Cempaka Hutagalung, Riris Br Hutagaol, Delvi Amira Huzeila Nisa Siregar Ihsan Fadhilah Ika Yeni Siahaan Ilmi Widya Sari Imelda Natasia Br S Meliala Indah Nasution Indah Triutami Harahap Indrayani, Gabena Junia Fitri Hayani Khofifah , Nur Kiki Rawitri Krisna Juniharta Napitupulu Leni Safriani Lestari, Sri Indah Linda, Rosa Liza Zulaini Lubis, Minda Sari lubis, muhammad fauzan Lubis, Nadya Frestika Luthfianida, Arifna M Pandapotan Nasution M Pandapotan Nasution M Pandapotan Nasution M. Alfaruqi M. Pandapotan Nasution M. Pandapotan Nasution M. Pandapotan Nasution Mambang , D.Elysa Putri Mambang, D. Elsya Putri Mambang, Elysa Putri Maya Syafira Mayani, Nurhikma Meutia, Cut Miftahul Jannah Minda Sar Lubis Muhammad Amin Nasution Muhammad Ari Mukhtizar Muhammad Hizbullah Muhammad Pandapotan Nasution Muhammad Wahyu Ikhsan, Muhammad Wahyu Ikhsan Munaziatul Jannah Munthe, Herlina Nasri Nasri Nasri Nasri, Nasri Nasution , Muhammad Amin Nasution, Kartika Zsaskia Nasution, M Pandapotan Nasution, M. Pandapotan Nasution, Nur Sahadah Nasution, Wardah Natasya, Siti Adinda Nazirah, Nazirah Nazuhra, Oca Nelsa Fahira Ningtias, Anggitha Niswa, Khairun Niza Fonna Nofa Lismandaria Novika Utami Nur Hanifah Nuraida Nuraida Nuratika, Eli Nurliansyah, Nurliansyah Nursyafira, Arini Nurul Hasanah Ovalina Sylvia Br. Ginting Pandapotan Nasution, M. Pertiwi, Rahma Prasetyo , Healthy Aldriany Purba , Intan Sabila Putri Puteri, Cut Intan Annisa Putri , Adilla Putri Intan Sari Putri Khairani Putri Mambang, D. Elysa Putri Rahayu, Yayuk Putri, Nadya Iwani Rafika, Intan Maya Rafita Yuniari Rafita Yuniart Rafliza , Rista Rahayu , Yayuk Putri Rahmadani , Adevika Rapita Yuniarti Rati , Yuliandini Rawitri, Kiki Ridho, Ahmad Rasyid Ridwanto Ridwanto Ridwanto Rifqi, M. Ainur Rina Azhari Ritonga , Septi Ani Riza Syafira Rizki, Ayu Fadillah RR. Ella Evrita Hestiandari Rukmana, Siti Sabila , Anisa Safira , Liyuza Safitri , Nurhaliza sahrianti, Hikmah Sari, Syilvi Rinda Sarmadansyah Sarmadansyah Sartika Daulay, Anny Sasnita, Merida Satri Situmorang, Rati Selfia Lestary Sepriani, Ananda Sinaga, Novita Yulianti Siregar , Anisah Siregar, Huzeila Nisa Siti Aisyah Jamil Situmorang, Lusi Grasia Situmorang, Rati Satri Sony , Suyefri Sri Harti Sri Natalia Saragih Sri Ria Ranti Sri Wahyuni Sri Wahyuni Sri Wahyuni Suci, Nurul Sulwiyatul K Sani Supiyani, Supiyani Syafira, Nona Syaiful Bahri Syalsabila Putri Syara, Nurdiani Syarifa Mayly Syarifah Elena Gultom Tawir Rina Rezeki Tri Damaiyanti Trizaldi, Asep Try Santi Kisria Darsih Ummi Khairani Rambe Vera Estefania Kaban Vera Estefania Kaban Wahdaniati , Tri Widya Sari Widya Sari Widya, Rizka Yani, Farida Yanti, Rahma Yayuk Putri Rahayu Yayuk Putri Rahayu Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Apriani Br.Lubis Yuniarti , Rafita Yuniarti, Rafita Zannah , Muhamad Zikra Maqfirah Ziza Putri Aisyia Fauzi Zulmai Rani