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Literature Review: Antioxidant Activity of Water Apple Leaves (Syzygium aqueum) Justisia, Adilla; Susianti; Jausal, Anisa Nuraisa; Busman, Hendri
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1321

Abstract

Antioxidant is a complex inhibit, prevent or dampen the reactions of free radicals and oxidants, as well as to prevent tissue damage. Antioxidant works by donating one of its electron to oxidant compounds thereby inhibiting the activity of these oxidant compounds. An imbalance between antioxidants and free radicals, where free radicals are more prevalent, can damage molecular organisms and cause oxidative stress that triggers damage to body cells. Oxidative damage to DNA triggers mutations that initiates cancer, cardiovascular disease, neurodegenerative disorder, autoimmune diseases, aging processes and several hereditary diseases. Currently, the use of natural antioxidants as traditional treatments is widely consumed by the community. Natural antioxidants are found in several plant sources, it is known to be more affordable and have lower side effects, making it as popular treatment choice in the community. One of the plants with a high antioxidant content is the water apple leaf (Syzygium aqueum) which rich in flavonoids, phenolics, and tannins. DPPH (2,2-diphenyl-1-picrylhydrazyl) is a common method to measure antioxidant activity, it works with the principle of hydrogen capture from antioxidants by free radicals. The parameter IC50 is used to represents the sample concentration required to capture 50% of DPPH radicals. Several studies using the DPPH method have shown that water apple leaves have strong antioxidant activity, indicated by its low IC50 value. The lower the IC50 value, the stronger the antioxidant activity.
Transient Ischemic Attack : Tantangan dalam Mendiagnosis Akuba, Nanda Nurrohim; Susianti; Daulay, Suryani Agustina; Berawi, Khairun Nisa
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1360

Abstract

Stroke is a condition characterized by the rapid development of clinical signs of focal and global neurological deficits, which can worsen and persist for 24 hours or more, potentially leading to death, with no clear cause other than vascular. Transient Ischemic Attack (TIA) is a temporary neurological dysfunction caused by a blockade or reduction in blood perfusion to brain tissue, lasting from a few seconds to minutes, and in some cases, up to 24 hours. Diagnosing TIA is challenging because patients typically present after the TIA has resolved, making it crucial to diagnose TIA clinically before confirming the diagnosis with additional examinations such as CT-Scan or MRI. There are meta-analysis studies that describe the role of certain biomarkers in supporting the diagnosis of TIA. Due to the closely related pathomechanisms between TIA and ischemic stroke, almost all the same biomarkers can be used to diagnose both conditions. There are scoring systems used to identify the risk of stroke in patients with TIA, with the ABCD² score being the most commonly used. Rapid assessment and the implementation of adequate therapy reduce the risk of TIA progressing to ischemic stroke.
Eksplorasi Imunoterapi dan Terapi Gen dalam Pengobatan Tumor Otak: Literature Review Hana Muthi'a Putri; Windarti, Indri; Mayasari, Diana; Susianti, Susianti
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1378

Abstract

Brain tumors are a significant neurological disorder with a high mortality rate, especially in cases of glioblastoma, which is highly aggressive and difficult to treat. Conventional treatment methods, such as surgery, radiation therapy, and chemotherapy, are often not effective enough, particularly in advanced stages. This study aims to explore two innovative approaches, namely immunotherapy and gene therapy, as alternative treatments for brain tumors. Immunotherapy works by enhancing the immune system's ability to fight cancer cells through methods such as checkpoint inhibitors, cancer vaccines, and CAR-T therapy. However, the success of immunotherapy is often hindered by the blood-brain barrier (BBB), which limits the delivery of therapy to the brain. On the other hand, gene therapy offers a solution by modifying genetic material, either to repair damaged genes or to directly destroy cancer cells. Approaches such as the use of oncolytic viruses, CRISPR technology, and nanoparticles have shown promising results in preclinical research and early clinical trials, particularly for glioblastoma. The combination of immunotherapy and gene therapy opens new opportunities to enhance treatment effectiveness by strengthening the immune response and targeting tumors more specifically. However, challenges remain, including treatment resistance, side effects, and limitations in brain delivery methods. Further research is needed to ensure the safety, efficacy, and widespread application of this combination therapy. Immunotherapy and gene therapy have great potential as breakthroughs in the future treatment of brain tumors. Relevant literature, including articles and journals from both national and international sources, were gathered through online searches in various databases, such as Google Scholar, PubMed, and NCBI, and used to compile this article.
Pengaruh Pemberian Ekstrak Etanol Buah Pare (Momordica Charantia L) Terhadap Gambaran Histopatolgi Arteri Koronaria Tikus Putih (Rattus Norvegicus) Jantan Galur Sprague Dawley Yang Diinduksikan Minyak Jelant Joni, Agnesia Priskila; Windarti, Indri; Oktarlina, Rasmi Zakiah; Susianti, Susianti
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1392

Abstract

Coronary heart disease is one of the main causes of death in the world, with more than 17 million deaths every year due to heart and blood vessel diseases, with around 8.7 million of them caused by coronary heart disease and around 15 out of 1000 residents in Indonesia which is equivalent to around 2,78,064 people suffer from coronary heart disease. The high frequency of use of cooking oil means that cooking oil is often used repeatedly. Repeated use of cooking oil can cause damage to various body organs such as the liver, heart, kidneys and arteries. Exposure to free radicals and free fatty acids obtained from used cooking oil if it enters the body will result in oxidative stress. The atherosclerosis process is characterized by the change of k-LDL to Ox-LDL which triggers endothelial dysfunction and the formation of atherosclerotic plaque on the walls of blood vessels. The high fatty acid content in used cooking oil can easily stick to the walls of blood vessels, so that it will accumulate and form atherosclerotic plaque. One of the alternative antioxidants that comes from herbs is bitter melon (Momordica Charantia L). Bitter melon contains flavonoid compounds. Flavonoids are secondary metabolites which are antioxidants that can inhibit free radical activity and can prevent atherosclerosis. Antioxidant compounds can reduce atherosclerosis by inhibiting LDL metabolism in secondary atherosclerotic lesions to prevent LDL oxidation in these lesions.
Peran Flavonoid Sebagai Antiulser dan Antioksidan pada Ulkus Duodenum Zahra, Aulia Jannatuz; Susianti, Susianti; Happy, Terza Aflika; Soleha, Tri Umiana
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1415

Abstract

Duodenal ulcer is a pathological condition characterized by damage to the duodenal mucosa due to an imbalance between protective and aggressive factors, such as gastric acid and pepsin. The primary factors contributing to the development of this ulcer include Helicobacter pylori infection. Additionally, prolonged use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) is also a significant factor in the occurrence of duodenal ulcers, as these drugs inhibit prostaglandin synthesis, which plays a crucial role in mucosal protection. In Indonesia, the prevalence of duodenal ulcers is estimated to be around 11–14%. Flavonoids, as bioactive compounds with antioxidant, anti-inflammatory, and anti-ulcer properties, have been widely studied for their potential in the management of peptic ulcers, including duodenal ulcers. Flavonoids have been shown to inhibit gastric acid secretion, stimulate mucus production, and protect the gastrointestinal mucosa through cytoprotective and antioxidative mechanisms, specifically by inhibiting reactive oxygen species (ROS). Furthermore, flavonoids have the ability to suppress H. pylori growth, thereby contributing to the prevention of ulcer pathogenesis caused by this bacterium. Flavonoids also enhance blood flow to the gastric mucosa and modulate enzymes involved in epithelial defense. Despite these benefits, the main challenges in utilizing flavonoids are their low bioavailability and potential toxicity at high doses. Therefore, further studies are essential to evaluate the efficacy, safety, and formulation optimization of flavonoids to enhance their availability as a natural therapeutic alternative and their application in the clinical treatment of peptic ulcers.
Potensi Daun Jambu Air (Syzygium aquem) sebagai Fitofarmaka : Literature Review Febrianti, Arlin; Susianti, Susianti; Kusumaningtyas, Intan; Mustofa, Syazili
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1456

Abstract

Traditional medicine widely utilizes plant extracts from various parts of plants due to their secondary metabolite content, which possesses therapeutic effects. One plant with high pharmacological potential is the water apple leaf (*Syzygium aqueum*), belonging to the Myrtaceae family and commonly found in tropical regions such as Indonesia, Malaysia, and India. Water apple leaves have been used as phytopharmaceuticals because they contain various bioactive compounds that can be extracted and utilized for treating different diseases. The active compounds commonly found in water apple leaves include alkaloids, flavonoids, steroids, triterpenoids, and coumarins. Studies have shown that water apple leaf extracts exhibit various pharmacological activities, including antibacterial, antioxidant, anti-inflammatory, anticancer, antimicrobial, and antidiabetic properties. Additionally, the bioactive compounds in water apple leaves have the potential to be further developed as natural therapeutic agents for treating degenerative diseases and infections. This pharmacological potential positions water apple leaves as a promising phytopharmaceutical candidate for development in the pharmaceutical and healthcare industries. However, further research is required to explore the mechanisms of action, efficacy, and potential toxicity of the active compounds in water apple leaves. A comprehensive study in this area will enable the optimization of water apple leaves as a safe and effective natural therapy for various diseases.
Pengaruh Pemberian Ekstrak Etanol Daun Pucuk Merah (Syzygium myrtifolium Walp) Terhadap Gambaran Sel Hepatosit Tikus Putih Jantan Galur Sprague-Dawley Ruslani, Nada Oktista; Susianti, Susianti; Graharti, Risti; Rudianto, Waluyo
Medula Vol 15 No 3 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i3.1693

Abstract

Syzygium myrtifolium Walp., commonly known as red shoot leaves, is an ornamental plant rich in bioactive compounds such as flavonoids, tannins, and terpenoids, which exhibit antioxidant, anticancer, and antibacterial properties. However, administration at high doses may lead to hepatotoxic effects. The liver plays a central role in drug metabolism and is the first organ exposed to toxic agents, making it highly susceptible to hepatocyte necrosis. This study aimed to evaluate the effect of ethanol extract of Syzygium myrtifolium leaves on liver histopathology in male white rats (Rattus norvegicus). This experimental study employed a post-test only control group design with three groups: control, 2000 mg/kgBW, and 5000 mg/kgBW. The extract was administered orally, and hepatocyte necrosis was assessed using a histopathological scoring system. Statistical analysis included Shapiro-Wilk, Levene’s Test, One Way ANOVA, and post hoc LSD. Histopathological examination revealed normal hepatocytes in the control group, focal necrosis in the 2000 mg/kgBW group, and extensive necrosis in the 5000 mg/kgBW group. Statistical analysis confirmed normally distributed and homogeneous data, while ANOVA indicated significant differences among groups (p=0.001). Post hoc LSD test further demonstrated significant differences between the control and treatment groups as well as between both treatment doses. In conclusion, oral administration of ethanol extract of Syzygium myrtifolium leaves induces hepatocyte necrosis in male white rats, with the severity of liver damage increasing in a dose-dependent manner.
Hubungan antara Pengolahan Sampah dan Limbah Rumah Tangga dengan Kejadian Stunting Ovalia, Nora Wilya; Suharmanto, Suharmanto; Susianti, Susianti; Saftarina, Fitria; Wahono, Endro Prasetyo
Indonesian Journal of Nursing and Health Sciences Vol 6 No 2 (2025): Indonesian Journal of Nursing and Health Sciences: October 2025
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijnhs.v6i2.7395

Abstract

Stunting adalah kondisi panjang atau tinggi badan yang kurang dibandingkan usia pada balita akibat kekurangan gizi kronis, terutama pada 1000 hari pertama kehidupan. Tujuan penelitian ini adalah untuk mengetahui hubungan antara pengelolaan sampah dan sampah rumah tangga dengan kejadian stunting. Penelitian ini merupakan penelitian analitik dengan pendekatan kasus kontrol pada bulan Agustus-September 2025. Populasi dalam penelitian ini adalah seluruh balita yang terdampak stunting pada usia 0-59 bulan menggunakan total sampling sebanyak 222 sampel. Variabel dalam penelitian ini adalah pengelolaan sampah dan limbah rumah tangga serta kejadian stunting. Alat pengumpulan data dalam penelitian ini meliputi kuesioner dan lembar observasi. Analisis data menggunakan chi square. Sebanyak 1,8% balita mengalami stunting dari ibu yang memiliki praktik pembuangan sampah yang memadai, sementara 98,2% berasal dari ibu yang memiliki praktik pembuangan sampah yang tidak memadai. Sementara itu, pada kelompok balita yang tidak mengalami stunting, 11,7% berasal dari keluarga dengan praktik pembuangan sampah yang memadai, dan 88,3% berasal dari keluarga dengan praktik pembuangan sampah yang tidak memadai. Nilai-p sebesar 0,006 menunjukkan adanya hubungan antara sampah rumah tangga dan pengelolaan sampah dengan kejadian stunting pada balita usia 0-59 bulan.
Screening Pertumbuhan dan Peningkatan Pengetahuan tentang Pola Makan Gizi Seimbang pada Siswa Sekolah Dasar Negeri di Kabupaten Lampung Selatan dalam Upaya Meningkatkan Derajat Kesehatan Anak Indonesia Mutiara, Hanna; Susianti, Susianti; Wulan, Anggraeni Janar; Soleha, Tri Umiana
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 1 No. 1 (2015): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v1i1.1148

Abstract

Pembangunan kesehatan memerlukan pemantapan dan percepatan melalui Sistem Kesehatan Nasional (SKN). Termasuk diantaranya adalah pendekatan peningkatan kesehatan dan pencegahan penyakit, yakni upaya promotif dan preventif. Penilaian status kesehatan anak penting dilakukan untuk mempersiapkan generasi masa depan yang sehat, cerdas, dan berkualitas. Salah satu upaya yang dapat dilakukan adalah memantau pertumbuhan anak dengan antropometri yang dapat menggambarkan status gizinya. Status gizi dapat dipengaruhi oleh pola makan. Pola makan adalah informasi yang memberikan gambaran mengenai jumlah dan jenis bahan makanan yang dimakan setiap hari oleh seseorang. Pola makan yang baik dapat memberikan zat giziyang diperlukan untuk pertumbuhan dan pemeliharaan tubuh serta perkembangan otak dan produktivitas seseorang. Kegiatan pengabdian dilakukan melalui pengukuran berat badan dan tinggi badan yang kemudian dihitung sehingga mendapatkan angka IMT. IMT kemudian dianalisis dengan mengacu pada Standar Antropometri Penilaian Status Gizi Anak, Kementerian Kesehatan RI 2010. Selain itu, dilakukan pula penyuluhan mengenai pola makan gizi seimbang untuk meningkatkan pengetahuan peserta. Peningkatan pengetahuan dinilai berdasarkan perbandingan nilai pre-test dan post-test. Hasil kegiatan ini adalah terdapat 84,8% peserta dengan status gizi normal, 9,1% peserta dengan status gizi kurus, 3% peserta dengan status gizi kegemukan dan 3%peserta mengalami obesitas. Peningkatan pengetahuan terdapat pada 89% peserta, namun terdapat 8% peserta dengan pengetahuan yang tetap dan 3% peserta dengan nilai pre-test yang lebih baik. Kegiatan ini bermanfaat dalam memantau pertumbuhan anak dan meningkatkan pengetahuan peserta, sehingga kegiatan serupa sebaiknya dilakukan secara kontinyu.Kata kunci: pertumbuhan, penyuluhan, pola makan gizi seimbang
Pemeriksaan Kadar Asam Urat dan Penyuluhan tentang Penyakit Gout pada Masyarakat di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan Susianti, Susianti; Kurniawan, Betta; Zuraida, Reni; Mutiara, Hanna
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 1 No. 1 (2015): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v1i1.1149

Abstract

Penyakit gout adalah salah satu tipe dari arthritis (rematik) yang disebabkan terlalu banyaknya atau tidak normalnya kadar asam urat di dalam tubuh. Di masyarakat beredar mitos bahwa ngilu sendi berarti penyakit asam urat. Pengertian ini perlu diluruskan, sehingga dirasa perlu untuk melakukan penyuluhan dan perlu dilakukan pemeriksaan kadar asam urat. Kegiatan dilaksanakan pada tanggal 15 November 2015 pukul 15.30 s.d. 17.30 WIB di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan dan dihadiri 31 orang warga yang didominasi oleh ibu-ibu rumah tangga. Metode yang digunakan dalam kegiatan ini adalah penyuluhan yang dilanjutkan dengan diskusi. Evaluasi yang dilakukan terdiri dari evaluasi awal (pre-test), evaluasi proses (pertanyaan saat diskusi) dan evaluasi akhir (post-test). Berdasarkan data hasil pengamatan diperoleh rata-rata nilai pre-test peserta 45,61 dan post-test 65,37. Setelah mendapatkan penyuluhan mengenai penyakit gout,terdapat peningkatan pengetahuan masyarakat di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan tentang penyakit gout. Setelah dilakukan penyuluhan, masing-masing peserta diperiksa kadar asam urat dalam darah yang diambil dari darah perifer dan diperiksa menggunakan stick. Dari hasil pemeriksaan didapatkanbahwa dari 31 orang peserta dan 10 orang yang memiliki kadar asam urat di atas normal. Itu berarti angka kejadian gout di desa Kalisari cukup tinggi. Terdapat peningkatan pengetahuan masyarakat di Desa KalisariKecamatan Natar Kabupaten Lampung Selatan tentang penyakit gout. Angka kejadian penyakit gout di Desa Kalisari Kecamatan Natar Kabupaten Lampung Selatan sendiri cukup tinggi.
Co-Authors Ade Yonata Adilla Justisia Aditya Kusumaningtyas Hudisaputeri Aditya Permana Agusta Saraswati Agustyas Tjiptaningrum Ahmad Farizan Radhitya Ahmad Syah Putra Ainin Aniah, Pratiwi Ajeng Defriyanti Pusparini Akuba, Nanda Nurrohim Aldo Fatejarum Ambarwati, Yuli Andhini, Friska Andi Setiawan Andrian Rivanda Andriansah, M. Anggi Setiorini Anggraeni Janar Wulan Anggraeni Janar Wulan, Anggraeni Janar Anisa Nuraisa Jausal Anisa Nuraisa Jausal Arif Setiawansyah Arini Meronica Arninda Rahman Atmajaya, Yudhi Audya Pratiwi Putri Riyanda Ayu Ningsih Ayu Tiara FItri Azkiya Bahren Nortajulu Balqis Mezzaluna D'Azzuri Bara Ade Wijaya Suprayitno Bayu Anggileo Pramesona Betta Kurniawan betta kurniawan Betta Kurniawan, Betta Buana, Faris Agung Cana, Arla Erit Siktia Catur Ariwibowo Catur Ariwibowo Damayanti, Putri Daulay, Suryani Agustina Dedi Hermawan Devi Rahmadiani Diah Septia Liantari, Diah Septia Dian Isti Angraini Dian Isti Angraini Dyah Wulan Sumekar Dyah Wulan Sumekar Rengganis Wardani Dyah Wulan Sumekar Rengganis Wardani Endro Prasetyo Wahono Ersa, Rakhmigasti Citra Ety Apriliana Ety Apriliana Ety Apriliana Eva Lusina, Septia Evi Kurniawati, Evi Evi Kurniawaty Exsa Hadibrata Fahrezi Fathilla Farida Hakim Lamuhammad Fatriyadi Suwandi, Jhons Febrianti, Arlin Fendi Setiawan Fitri Sofiatin Fitria Saftarina Gemayangsura Gemayangsura Gemayangsura, Gemayangsura Giok Pemula Giska Tri Putri Hadibrata, Exsa Hana Muthi'a Putri Handayani Dwi Utami Hanna Mutiara, Hanna Happy, Terza Aflika Hardiansyah, Ridwan Hendra Tarigan, Sibero Hendri Busman Hendri Busman Hijami, Nurul 'Afifah Ibnu Fadilah Indri Windarti Intan Kusumaningtyas Intanri Kurniati Irawan Budi Waskito Irma Liani Ismunanto, Aziza Regina Kinasih Isvari, Gusti Ayu Made Prathita Iswandi Darwis Janar Wulan, Anggraini Jausal, Anisa Nuraisa Jhons Fatriyadi Suwandi John Hendri Joni, Agnesia Priskila Justisia, Adilla Kamalia, Avissa Medina Khairun Nisa Khairun Nisa Kinanti Rahmadhita Kurniawaty, Evi Lanang Rachmadi M. Ridho Ulya M. Yusran Mallarangeng, Andi Nafisah Tendri Adjeng Marcellia, Selvi Maya Ganda Ratna Mayasari, Diana Mela Liberti Octoriani Simaremare Merry Indah Sari Muhamad Yogie, Fadli Muhammad Ariq Naufal Muhammad Yogie, Fadli Muhartono Muhartono Muhartono Muhartono Muhartono Sudarmo Kasban Nabila Shafira Naufal, Muhammad Ariq Ni Luh Gede Ratna Juliasih Ni Putu Sari Widiyani Nisa Karima Nisa Karima Novianty, Detty Novita Carolia Novita Carolia Nurhasanah Nurhasanah Oktadoni Saputra, Oktadoni Oktafany Oktafany Ovalia, Nora Wilya Pemula, Giok Peni Ahmadi Pratiwi, Ainin Aniah Putri, Najwa Naraniya Putu Ristyaning Ayu R Supriyanto Rachel Junita Sitepu Ramadhana Komala Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Ratna, Maya Ganda Ratri Mauluti Larasati Reimma Emily Rachman Rengganis Wardani, Dyah Wulan Sumekar Reni Zuraida Rianto, Muhamad Arif Rie Dahniar Marissa Marpaung Rika Lisiswanti Rika Oktaria Rinawati Rinawati Risal Wintoko Riski Pangestu Risti Graharti Rizki Hanriko Rodiani Rodiani Rodiani, Rodiani Roro Rukmi Windi Perdani, Roro Rukmi Rosbhaiti Chodijah Rudianto, Waluyo Rudiyanto, Waluyo Ruslani, Nada Oktista Sangging, Putu Ristyaning Ayu Septia Eva Lusina Septiani, Linda Siti Raqiya Rasyid Smith Imanuel Saputra Sofyan Musyabiq Wijaya Soraya Rahmanisa Soraya, Yeni Sri Agustina Suharmanto Suharmanto Suharmanto Sulthan Alam Yasyfa Surriandari, Latifah Dwi Suryadi Islami Suryani Agustina Daulay Sutarto Sutarto Sutarto Sutopo Hadi Sutyarso Sutyarso Sutyarso Sutyarso Sutyarso Syafira Alifia Audiani Syaiful Bahri SYAIFUL BAHRI Syazili Mustofa Tara Aulianova Tasya Hani Fatwa Tri Umiana Soleha Tutik Ernawati Victoria Hawarima W, Dyah Wulan Sumekar R. W., Dyah Wulan Sumekar R. Waluyo Rudianto Waluyo Rudiyanto Wardani, Dyah Wulan Wawan Abdullah Setiawan Wido Gamani Worocahyo, Avis Meyvika Yadika, Adilla Dwi Nur Yolanda Fratiwi Yudhi Atmajaya Yudho Prabowo, Arif Yunianto, Andi Eka Yuningrum, Hesti Zahra, Aulia Jannatuz Zakiah Zakiah