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All Journal International Journal of Public Health Science (IJPHS) Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal Presipitasi : Media Komunikasi dan Pengembangan Teknik Lingkungan Jurnal Vektor Penyakit Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Pharmaciana: Jurnal Kefarmasian Journal of Degraded and Mining Lands Management Mutiara Medika: Jurnal Kedokteran dan Kesehatan JURNAL PHARMASCIENCE JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) INDONESIAN JOURNAL OF PHARMACY Dentino: Jurnal Kedokteran Gigi Pharmascience Berkala Kedokteran The Indonesian Biomedical Journal Sari Pediatri Padjadjaran Journal of Dentistry Panrita Abdi - Jurnal Pengabdian pada Masyarakat Jurnal Ilmiah Kedokteran Wijaya Kusuma Universa Medicina JURNAL KESEHATAN LINGKUNGAN: Jurnal dan Aplikasi Teknik Kesehatan Lingkungan Medical Laboratory Technology Journal Jurnal Berkala Kesehatan JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) EnviroScienteae Jukung (Jurnal Teknik Lingkungan) BAREKENG: Jurnal Ilmu Matematika dan Terapan SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Media Ilmu Kesehatan JURNAL PENDIDIKAN TAMBUSAI Jurnal Kreativitas PKM Manuju : Malahayati Nursing Journal JKM (Jurnal Kebidanan Malahayati) Acta Biochimica Indonesiana YARSI Medical Journal Jurnal Respirasi (JR) Jurnal Jejaring Matematika dan Sains Jurnal Ners An-Nadaa: Jurnal Kesehatan Masyarakat Science Midwifery Bubungan Tinggi: Jurnal Pengabdian Masyarakat BERNAS: Jurnal Pengabdian Kepada Masyarakat Indian Journal of Forensic Medicine & Toxicology JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Indonesian Journal of Perinatology Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Ilung (Inovasi Lahan Basah Unggul) Jurnal Pengabdian Masyarakat Formosa (JPMF) JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Biological Environment and Pollution Smart Society Empowerment Journal Homeostasis: Jurnal Mahasiswa Pendidikan Dokter DUNIA KEPERAWATAN: JURNAL KEPERAWATAN DAN KESEHATAN Gunung Djati Conference Series Jurnal AGRISEP: Kajian Masalah Sosial Ekonomi Pertanian dan Agribisnis Leuser Journal of Environmental Studies Biosaintifika: Journal of Biology & Biology Education Journal of Advanced Research in Social Sciences and Humanities Journal of Management Practices, Humanities and Social Sciences
Eko Suhartono
Departement Of Medical Chemistry/Biochemistry, Faculty Of Medicine, Universitas Lambung Mangkurat, Jl. Ahmad Yani Km.36, Banjarbaru 70712
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Oxidative Stress on Buccal Mucosa Wound in Rats and Rule of Topical Application of Ethanolic Extracts of Mauli Banana (Musa acuminata) Stem Noor, Wenda Fitriati; Aprianti, Novie; Saputra, Saldy Rizky; Apriasari, Maharani Laillyza; Suhartono, Eko
Journal of Tropical Life Science Vol 5, No 2 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.05.02.05

Abstract

The present study was undertaken to evaluate the effect of a topical application of ethanolic extracts of Mauli banana stem on buccal mucosa wounds in rats (Rattus novergicus). Three sets of experiments with 3 groups male rats each consisted of 9 animals were used for studying wound oxidative stress status. Group 1 (P0) as the negative control was left to heal spontaneously; group 2 (P1) as the postive control were treated with alocair topically; and group 3 (P2) as treatment group were treated with ethanloic extracts of Mauli banana stem topically, respectively, 24h after wound creation for 3 days. The oxidative stress status was evaluated by monitoring the SOD, CAT activity, MDA and CC levels. The effect of ethanolic extracts of Mauli banana stem on oxidative stress status revealed significant increased in SOD activity, decreased in MDA levels, and no significant change both in CAT activity and CC levels compared to negative control. These results showed that The ethanolic extracts of Mauli banana stem might affect the oxidative stress status during wound healing process. Key Word : Antioxidant, Free Radicals, Mauli banana, Oxidative Stress, Wound Healing.
Kinetic Parameters Analysis of Liver and Kidney Catalase Under The Influence of Cadmium and Mercury In Vitro Karantika, Ellsa Anggun; Supianur, Supianur; Edyson, Edyson; Suhartono, Eko
Journal of Tropical Life Science Vol 6, No 2 (2016)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.06.02.01

Abstract

Cadmium (Cd) and mercury (Hg) are toxic metals that affect human organs function, including liver and kidney. This toxic activity is because the heavy metal could induce oxidative stress and interfere antioxidant activities, including catalase (CAT). The present study was aims to evaluate the effect of Cd and Hg to liver and kidney CAT kinetic parameters in vitro. In this experiment, liver and kidney were taken from male rats (Rattus novergicus). Sample the homogenized and divided into three groups with; T0 served as control which contains liver or kidney homogenate + H2O2, T1 which contains liver or kidney homogenate + H2O2 + 0.03 mg/L CdSO4; and T2 which contains liver or kidney homogenate + H2O2 + 1 mg/L Hg. Solutions then incubated at 37ºC for 1 hour and then was prepared for CAT activity measurement. The CAT activity was measured using spectrophotometer at 240 nm. For measuring the kinetic parameters, different concentration of H2O2 were used. The kinetics parameters (Km and Vmax) were calculated using Lineweaver-Burk plot. The results shows that Cd and Hg could decrease the affinity of CAT-H2O2 complex which expressed by the higher Km and Vmax values. Also from the results, Cd has better activity to decreased the affinity of CAT-H2O2 complex than Hg. From this results, it can be concluded that Cd and Hg treatments could inhibit CAT activity in liver and kidney in vitro.
Clinical and Laboratory Features of COVID-19 in Ulin Referral Hospital of South Kalimantan: Predictors of Clinical Outcome Haryati, Haryati; Isa, Mohamad; Assagaf, Ali; Nurrasyidah, Ira; Kusumawardhani, Erna; Suhartono, Eko; Arganita, Fidya Rahmadhany
Journal of Tropical Life Science Vol 11, No 3 (2021)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.11.03.06

Abstract

Corona Virus Disease (COVID-19) is becoming a global pandemic. Indonesia, especially South Kalimantan had recorded increasing cases with a high fatality rate of 3.7%. Information about factors related to outcomes based on clinical and laboratory features in Indonesia is still limited. Identification of the risk is crucial to determine optimal management and reducing mortality. This retrospective study enrolled 455 adults COVID-19 patients, and data were extracted from medical records of Ulin General Hospital Banjarmasin. The latter is COVID-19 referral hospital in South Kalimantan between March-November 2020. Demographic data, comorbidities, and laboratory were all collected. Data were compared between survivors and non-survivors. Fisher’s exact test and chi-square were used to compare categorical variables. The Mann_Whitney U test was used to compare continuous variables. Analysis was continued by multivariate logistic regression then receiver operating characteristic (ROC) curve to determine cut-off value. The multivariate analysis showed that number of comorbidities [odds ratio (OR) 1,339 (95% confidence interval (CI): 1,064-1,685, P = 0,013) was a significant risk factor to the outcome. In laboratory, lactate dehydrogenase (LDH) [OR: 1.001, 95% CI: 1,000-1.002, P = 0.001], Ferritin (OR 1.000, CI: 1,000-1.001, P = 0.013), APTT (OR: 1.045, CI: 1.010-1.082, P = 0.012), and D-dimer (OR: 1.188, CI: 1.064 - 1.327, P = 0.002) were significant predictor factors but only LDH, ferritin, and D- dimer were obtained good AUC 0.731, 0.715, and 0.705, respectively. The cut of the value of LDH was 656.5 U/L, ferritin was 672.18 ng/ml, and D-dimer was 2.28 mg/L. Sensitivity and specificity were 66.7% and 68,0% for LDH, 83,2% and 56,3% for ferritin, and 62,8 and 70,8% for D-dimer. From this research, we revealed that the number of comorbidities was a risk factor for death. Elevated LDH, ferritin, and D-dimer could be good predictive factors for poor outcomes, thereby considering the accelerating management of COVID-19 patients.
Evaluation of Antioxidant Activity of Some Selected Tropical Fruits in South Kalimantan, Indonesia Efrilia Tanjung; Muhammad Hafidz MS; Iskandar Thalib; Eko Suhartono
Journal of Tropical Life Science Vol. 4 No. 3 (2014)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.04.03.09

Abstract

In the present study antioxidant and antioxidant activity of some tropical fruits was evaluated. Antioxidants are compounds or molecules that can scavenging and prevent free radicals and reactive oxygen species that can caused a cell damage. Fruit was known as a source of antioxidant. South Kalimantan Indonesia, has a variety of fruit such as mentega, nangka, timun suri and kuranji. Study for evaluating the antioxidant levels and activity of those fruit were never been investigated. Thus, our study aim to measure the antioxidant levels and antioxidant activtity of those selected fruits. Ascorbic acid, lycopene, b-carotene levels and antioxidant activtity of four selected tropical fruits was evaluated using spectrophotometer. The result of this studied suggest that the four selected tropical fruits is potential antioxidant because it contained ascorbic acid, b-carotene, lycopene and had effect of scavenging radical hydroxyl, hydrogen peroxide and chellating ferrous iron.
Anti-Lipid Peroxidation Activities of Three Selected Fruits Juices Against Cadmium Induced Liver Damage In Vitro Eko Suhartono; June Astri Nijka; Vini Yulia Anhar; Rizki Amalia Sari; Edyson Edyson; Dona Marisa
Journal of Tropical Life Science Vol. 5 No. 2 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.05.02.03

Abstract

Cadmium (Cd) is one of the most toxic heavy metal. Numerous tissues both in vitro and in vivo suggest that Cd induced lipid peroxidation. The presence of antioxidant can inhbit this process. This present study was designed to determine the effects of mango, papaya, and banana juices on on malondi aldehyde levels (MDA, product of cellular lipid peroxidation) during Cd exposure in vitro. Significant differences was observed between three selected fruits juices and MDA levels and also between concentration of fruits juices and MDA levels. The highest correlation was found between banana juices and MDA levels with IC50 1,12, and followed by papaya and mango juices with IC 50 1,37 and 3,87 respectively. The findings of this study suggest that the three selected fruits juices may exert its protective action against Cd-induced lipid peroxidation in liver homogenate in vitro possibly through its antioxidant mechanism.Key WordCadmium, Lipid Peroxidation, Antioxidant Activity and Fruits Juices
Oxidative Stress on Buccal Mucosa Wound in Rats and Rule of Topical Application of Ethanolic Extracts of Mauli Banana (Musa acuminata) Stem Wenda Fitriati Noor; Novie Aprianti; Saldy Rizky Saputra; Maharani Laillyza Apriasari; Eko Suhartono
Journal of Tropical Life Science Vol. 5 No. 2 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.05.02.05

Abstract

The present study was undertaken to evaluate the effect of a topical application of ethanolic extracts of Mauli banana stem on buccal mucosa wounds in rats (Rattus novergicus). Three sets of experiments with 3 groups male rats each consisted of 9 animals were used for studying wound oxidative stress status. Group 1 (P0) as the negative control was left to heal spontaneously; group 2 (P1) as the postive control were treated with alocair topically; and group 3 (P2) as treatment group were treated with ethanloic extracts of Mauli banana stem topically, respectively, 24h after wound creation for 3 days. The oxidative stress status was evaluated by monitoring the SOD, CAT activity, MDA and CC levels. The effect of ethanolic extracts of Mauli banana stem on oxidative stress status revealed significant increased in SOD activity, decreased in MDA levels, and no significant change both in CAT activity and CC levels compared to negative control. These results showed that The ethanolic extracts of Mauli banana stem might affect the oxidative stress status during wound healing process. Key Word : Antioxidant, Free Radicals, Mauli banana, Oxidative Stress, Wound Healing.
Phytochemical Analysis, Anti-Inflammatory, and Antioxidant Activity of Selected Medicinal Plants in Mandiangin Rainforest in South Kalimantan, Indonesia: Medicinal Plants in Mandiangin Rainforest in South Kalimantan Yusanto Nugroho; Windy Budianto; Salmon Siahaan; Purwakaning Agung; Iskandar Thalib; Eko Suhartono
Journal of Tropical Life Science Vol. 13 No. 1 (2023)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.13.01.14

Abstract

Mandiangin is one of the tropical rainforests in South Kalimantan, with highly diverse plants used for health and medicinal purposes. To date, scientific evidence on these plants' content and bioactivities remain lacking for further medical applications. In this perspective, this study aimed to determine the phytochemical contents of six selected plants, which include the Bilaran Kusan (Passiflora foetida), Sembilakan (Caesalpinia sp), Bamban Batu (Donax cenniformis), Kilayu (Aglaia sp), Ulur-Ulur (Tetrastigma sp), and Mali-Mali (Leea indica) from the Mandiangin rainforest, in addition to their antioxidant and anti-inflammatory activity. Results revealed that the Leea indica extracts exhibited the highest flavonoid content (70.892 ± 0.34 mg/ml QE), while the highest tannin (2.101 ± 0.02 mg/ml GAE) and alkaloid contents (25.30 ± 0.71 %) were recorded for the Aglaia sp species. Meanwhile, Passiflora foetida showed the highest saponin content at (31.78 ± 2.97 %). Based on the study findings, the extracts of all six plants from the Mandiangin rainforest possessed medically valuable phytochemical constituents, as seen from their appreciable antioxidant and anti-inflammatory activity. Of all these plants, P. foetida and L. indica demonstrated the highest antioxidant activity, whereas the highest anti-inflammatory activity was noted for the P. foetida, Aglaia- and Caesalpinia species.
Co-Authors - Edyson - Haudhiya - Mashuri - Mashuri, - Abd Rahman, Sunarti Abdullah Fadily Achmad Syamsu Hidayat Adenan Adenan, Adenan Adi Kristanto Adi Nugroho Adi Nugroho Adi Nugroho Afriyanti, Defi Agianto Agung Biworo Agung Biworo Agung Biworo Ahmad Hidayat Ahmad Husairi Akhmad Rizali Ali Assagaf Aminuddin Prahatama Putra Aminuddin Prahatama Putra Aminuddin Prahatama Putra Anang Kadarsah Anang Kadarsah, Anang Anes Fikri Haekal Angga Praditya Anggraini, Farida Anindya Anindya Anindya, Anindya Anni Nurliani Annisa Halida Husna Annisa Halida Husna, Annisa Halida Aranda, Viren Lolita Ardik Lahdimawan, Ardik Arfan Eko Fahrudin Arganita, Fidya Rahmadhany Ari Yunanto Ari Yunanto Ari Yunanto Arifin Syamsul Arjan Arkasi Arrifah Noer Emma As, Zufikar Ali Asdar Gani, Asdar Asnawati Asnawati Aurenada, Syabita Azka Lahdimawan Badaruddin Badaruddin Bahrul Ilmi Bahrul Ilmi Bakhriansyah, Bakhriansyah Bakhriansyah, M. Bambang Setiawan Bambang Setiawan Bambang Setiawan Basir Achmad Cahyadi, Herry Deni Fakhrizal Denny Margono Denny P.N.H. Margono Denny P.N.H. Margono, Denny P.N.H. Dewi Anggraini Dewi Hariyani DEWI SARTIKA Dewi Sri Susanti Dewi, Renie Kumala Diani, Holly Dicky Andiarsa Didik Triwibowo Dita Apriliana Sari Dona Marisa, Dona Donna Marisa Donna Marisa, Donna Edi Hartoyo Edi Hartoyo Edyson Edyson Edyson Edyson, Edyson Edyson, - Efrilia Tanjung Eka Santi Eko Suhartono Eko Suhartono Emmy Sri Mahreda Endah Ayu Rahmadhani Endah Ayu Rahmadhani, Endah Ayu Endah Rusdiana Eria Sartika Eriana, Nisa Nur Agistni Erida Widyamala Erlena, Erlena Erliyanti, Emmi Ermina Istiqomah, Ermina Fahira, Nurul Savira Fakhrur Razie Fakhrurrazy Fakhrurrazy Farizka Erianti Farizka Erianti, Farizka Fatmawati Fatmawati Fauzie Rahman Febriyasy, Fathia Ferdinand Aprianto Tannus Fujiati ., Fujiati Fujiati Fujiati Ganesh, Rajendran Ghazi Mauer Idroes Gunawan Hadianto, Teguh Hafifah, Ifa Hafiz Al Farizi Hamrun, Nurlinda Handayani, Rini Haryati Haryati Haryati Haryati Haryatie, Haryatie Haudhiya, - Heny Arwati Herawati Herawati Heru Cahjono Hidayati, Novita Husaini Husaini Husaini Husaini Husaini Husaini Husaini Husaini Husaini Husnul Khotimah Ibrahim, Sayed Ida Yuliana Idroes, Ghalieb Mutig Ika Kustiyah Oktaviyanti Illiandri, Abdullah Oski Insanul Kamilah Ira Nurrasyidah Isa, Mohamad Iskandar Iskandar Iskandar Iskandar Iskandar Iskandar Isna Syauqiah Isnasyauqiah, Isnasyauqiah Istiana Istiana Iwan Aflanie Joneks Aldianto Kabes June Astri Nijka Juniarti, Maya Kadarsah , Anang Kamilah, Insanul Karantika, Ellsa Anggun Kasmasari, Kasmasari Khairan Khairan Khairina Khairina Khairina Khairina, Khairina Krisdianto Krisdianto Krisdianto Kusumawardhani, Erna Kusumo, Fitranto Lenie Marlinae Lenie Marlinae Lenie Marlinae Liestiana Indriyati Liling Triyasmono Lisda Hayatie, Lisda Lutfhi Fatah M Irwan Setiawan M Surya Hermawan M. Bakhriansyah, M. Madargerong, Vincentius Adrian Maharani Laillyza Apriasari Mahmudah Maria Ulfah Maria Yosephine Himawan Martiani Martiani, Martiani Mashuri Mashuri Mashuri Mashuri Mashuri Mashuri Mashuri, Mashuri Maula, Ni’mal Maulana, Aga Maya Juniarti Medyan Riza Meitria Syahadatina Noor Meitria Syahadatina, Meitria Mijani Rahman, Mijani Mirza Maulana Ahmad Mohamad Isa Mohammad Bakhriansyah Mohammad Bakhriansyah Mohammad Rizki Fadhil Pratama Muchamad Arief Soendjoto Muhammad Abdan Shadiqi Muhammad Hafidz MS Muhammad Hendy Arizal Muhammad Hendy Arizal, Muhammad Hendy Muhammad Pahruddin, Muhammad Muhammad Rasyid Ridha Muhammad Rizky Tri Aditya Muhammad Rizky Tri Aditya, Muhammad Rizky Tri Muhammad Topan Widyanto Muhammad Topan Widyanto, Muhammad Topan Multiansyah, Multiansyah Musafaah Musafaah Muthia Elma Nabila Rahman Nadia Eka Pratiwi Nastiti, Titis Nelly Al Audhah Nia Kania Nila Nirmalasari, Nila Nindya Tresiana Putri Noer Komari Noor Muthmainah Noor, Ihsan Noor, Meitria Syahdatina Nopi Stiyati Prihatini Nova Eka Wondasari Novie Aprianti Novie Aprianti, Novie Nugi Maulana Nur Qamaliah Nur Qamariah Nur Yulia Sari Nur, Radian Nurul Hidayah Nurul Salsabila Yasmina Nuryandi Khairunanda Nuryandi Khairunanda, Nuryandi Olivia Sari, Devi oni Soesanto Patricia Sator Prahatama Putra, Aminuddin Prasetio, Rasi Prastricia, Meily Andini Pratama, Muhammad Noor Aditya Pricilia Gunawan H Pricilia Gunawan Halim Prihartini, Nopi Stiyati Purnama, Sapta Heru Purwakaning Agung Purwanto Budi Santosa Putera, Gusti Muhammad Perdana Rahayu, Istuning Puji Rahmiyati Rahmiyati Rima Permata Sari Rinawati Rino Rino Rismia Agustina Rizka Maulida Rizki Amalia Sari Rizki Perdani Rizqi Puteri Mahyudin ROBIATUL ADAWIYAH Rony Riduan Rosalia Friska Ananda Roselina Panghiyangani Rosihan Adhani, Rosihan Ruslan Muhyi Ruslan Muhyi, Ruslan Ruslan Ruslan Salamiah . Salamiah Salamiah Saldy Rizky Saputra Saldy Rizky Saputra, Saldy Rizky Salmon Charles P.T. Siahaan Salmon Charles Pardomuan Tua Siahaan Salmon Siahaan Salsabila, Salsabila Samsul Hadi Samsul Hadi Sanyoto, Didik Dwi Sapphira, Nadira Sari, Nur Yulia Sartika, Eria Savira Angelia Sekartaji, Hapsari Lintang Setiawan, Bambang Setiawaty, Endang Silvia Kristanti Tri Febriana Silvia Kristanti Tri Febriana Silvia Kristanti Tri Febriana Siti Arika Bulan Siti Juliati Siti Juliati Soesanto, Bayu Sri Cahyo Wahjono Sri Oktawati, Sri Suciati Suciati Suhastinah, Suhastinah Suhendrayatna Suhendrayatna Sumi Kartika Sunardi Sunardi, Ph.D., Sunardi Supianur, Supianur Susantu, Susantu Susilawati Susilawati Susilo, Tanto Budi Syachrumsyah, Muchlisch Syafa’ah, Irmi Syamsiar, Syamsiar Syamsul Arifin Syamsul Arifin Tamtama, Tatang Taupik Rahman Tazkia Safarina Tenri Ashari Wanahari Teuku Rizky Noviandy Trang, Ha Thi Thu Triawanti Triawanti Triawanti Triawanti Triawanti Triawanti Triawanti Triawanti Triawanti Trisnu Satriadi Vini Yulia Anhar Wardani, Hesti Sasmila Warih Anggoro Mustaqim, Warih Anggoro Waty, Marsela Umbar Wenda Fitriati Noor Wenda Fitriati Noor, Wenda Fitriati Wenny Wulandani Wijaya, Herman Wiji Cahyadi Windy Budianto Windy Yuliana Budianto, Windy Yuliana Wiwied Ekasari Wydiamala, Erida Yaliza, Nella Yuni Yulida Yusanto Nugroho Yuyun Hidayat Zahriah, Zahriah Zairin Noor Zoelkarnain Akbar, Izaak Zuchra Helwani, Zuchra