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Bioprospeksi Senyawa Antibakteri dari Bakteri yang Berasosiasi pada Bulu Babi asal Kabupaten Kaur, Bengkulu Wibowo, Risky Hadi; Sipriyadi, Sipriyadi; Adfa, Morina; Prastya, M. Eka; Cahlia, Uci; Fahmi, Riziq Ilham Nur; Rothman, Dita Delia
Jurnal Kelautan Tropis Vol 28, No 3 (2025): JURNAL KELAUTAN TROPIS
Publisher : Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jkt.v28i3.29412

Abstract

The digestive system of sea urchins functions to process organic material from food into bioactive compounds. . However, the direct exploitation of bioactive compounds from sea urchins may trigger ecological imbalances. These bioactive compounds can also be produced through interactions between sea urchins and their diverse associated bacteria within the body. Therefore, alternative methods are needed to obtain bioactive compounds without disrupting the aquatic ecosystem. This study aims to explore bioactive compounds from the associated bacteria of sea urchins (Stomopneustes variolaris Lamarck and Tripneustes ventricosus Lamarck) originating from Kaur Regency, Bengkulu. A total of 30 bacterial isolates were successfully obtained using Zobell Marine Agar (ZMA) medium. Potential isolates were identified through morphological observation, Gram staining, and biochemical tests. Antibacterial activity assays showed that 12 isolates had potential as antibacterial producers based on tests against Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Two isolates, TVL 6 and TVL 11, were able to inhibit all test bacteria. Additionally, assays using pellets and supernatants showed that all 12 isolates exhibited antibacterial activity, with 5 isolates showing activity in the supernatant. Isolates TVL 6 and TVL 11 were proven effective in inhibiting all test bacteria in both pellet and supernatant forms, with the highest inhibition observed against Staphylococcus aureus. These results indicate that the associated bacteria in the digestive tract of sea urchins have potential as candidates for antibacterial compound producers.   Sistem pencernaan bulu babi berfungsi untuk mengolah bahan organik dari makanan menjadi senyawa bioaktif. Namun, eksploitasi senyawa bioaktif dari bulu babi secara langsung dapat memicu ketidakseimbangan ekosistem. Senyawa bioaktif ini juga dapat dihasilkan melalui interaksi antara bulu babi dengan bakteri asosiasi yang beragam di dalam tubuhnya. Oleh karena itu, diperlukan metode alternatif untuk memperoleh senyawa bioaktif tanpa merusak keseimbangan ekosistem perairan. Penelitian ini bertujuan untuk mengeksplorasi senyawa bioaktif dari bakteri asosiasi bulu babi (Stomopneustes variolaris Lamarck dan Tripneustes ventricosus Lamarck) asal Kabupaten Kaur, Bengkulu. Sebanyak 30 isolat bakteri berhasil diisolasi menggunakan media Zobell Marine Agar (ZMA). Identifikasi isolat potensial dilakukan melalui pengamatan morfologi, pewarnaan Gram, dan uji biokimia. Uji aktivitas antibakteri menunjukkan bahwa 12 isolat memiliki potensi sebagai penghasil antibakteri berdasarkan pengujian terhadap kultur uji Bacillus subtilis, Escherichia coli, dan Staphylococcus aureus. Dua isolat, TVL 6 dan TVL 11, mampu menghambat semua bakteri uji tersebut. Selain itu, pengujian menggunakan pelet dan supernatan menunjukkan bahwa 12 isolat mampu menghasilkan aktivitas antibakteri, dengan 5 isolat menunjukkan aktivitas pada supernatan. Isolat TVL 6 dan TVL 11 terbukti efektif menghambat semua bakteri uji baik pada pelet maupun supernatan, dengan penghambatan tertinggi terhadap Stapylococcus aureus. Hasil ini mengindikasikan bahwa bakteri asosiasi dalam saluran cerna bulu babi memiliki potensi sebagai kandidat penghasil antibakteri. 
Efikasi Antibakteri; Staphylococ pengembangan e-modul mikrobiologi berbasis penelitian pemanfaatan kulit buah kabau sebagai antibakteri untuk meningkatkan keterampilan berpikir kritis mahasiswa Sitorus, Lizken; Sipriyadi; Nursa’adah, Euis
PendIPA Journal of Science Education Vol 9 No 3 (2025): October
Publisher : UNIB Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/pendipa.9.3.861-865

Abstract

The bark of the traditional plant, Archidendron bubalinum, known locally as kabau, exhibits promising qualities as a natural antibacterial agent. This research was conducted with two main objectives: (1) to evaluate the antibacterial efficacy of kabau fruit peel extract against two common pathogenic bacteria, Staphylococcus aureus and Escherichia coli, and (2) to design, validate, and assess the effectiveness of a research-based Microbiology E-Module in fostering students' critical analytical skills. The antibacterial capacity was tested using the paper disc diffusion method across a range of extract concentrations (5%, 10%, 20%, 40%, and 80%), using both pure water (aquades) and 2% dimethyl sulfoxide as carriers. Statistical analysis (one-way ANOVA, p = 0.020 < 0.05) indicated a notable difference in the zone of inhibition diameter across the various concentrations. The most potent antibacterial effect was observed at the 80% concentration with the aquades solvent, yielding inhibition zones of 3.97 mm against S. aureus and 8.42 mm against E. coli. These empirical results served as the core content for the innovative E-Module. The developed E-Module attained a high level of validity, achieving a CVR score of 1.00 from 5 expert validators, thus confirming its readiness for use. Subsequent evaluation during instructional application revealed a marked elevation in students' critical thinking abilities. Students in the Biology Department at FMIPA, Universitas Bengkulu, showed an initial mean pre-test score of 41.67, which surged to 88.00 in the post-test. This change resulted in an N-gain score of 0.79, positioning the improvement in the "high" category. Therefore, A. bubalinum extract is confirmed to hold antibacterial potential, and the E-Module is proven to be an effective educational tool for enhancing students' critical thinking competence.
PELATIHAN PEMBUATAN ECOENZYME "CAIRAN SERBA GUNA" SEBAGAI BAHAN ALTERNATIF BIO-HANDSANITIZER DAN BIOFERTILIZER PADA KELOMPOK TANI DESA SUKA SARI, KECAMATAN KABAWETAN, KABUPATEN KEPAHIANG Wibowo, Risky Hadi; Sipriyadi, Sipriyadi; Adfa, Morina; Hidayah, Thoriqul; Indah Medani, Della; Silvia, Elsi; Wahyuni, Reza
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 5, No 1 (2022): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v5i1.376-384

Abstract

Limbah organik berupa sayuran dan buah-buahan di Desa Sukasari, Kabupaten  Kepahiang, Kota Bengkulu yang melimpah dapat dijadikan sebagai produk Eco-enzyme sebagai bahan alternatif pembuatan Bio-handsanitizer dan Biofertilizer. Dari hasil kegiatan pengabdian kepada masyarakat mengenai aplikasi pemanfaatan ecoenzyme dari limbah organik sebagai bahan alternatif pembuatan Bio-handsanitizer dan Bio-fertilizer, para kelompok tani  telah mengetahui dan memahami cara pembuatan dan manfaat ecoenzyme. Hal ini menunjukkan kegiatan pengabdian sukses dan mencapai sasaran. Sosialisasi dan demonstrasi pelatihan yang dilakukan memberikan hasil persentase yang baik ketika pemberian umpan balik kepada peserta. Maka dari itu kegiatan pengabdian ini diharapkan untuk dapat memberi solusi terhadap kasus  pengolahan serta penanganan limbah organik melalui pembuatan produk ecoenzyme sebagai bentuk pengolahan limbah organik, seperti limbah sisa buah dan sayur dan diharapkan dapat memberi manfaat berupa wawasan untuk dimanfaatkan dalam realisasi produk ecoenzyme di Desa Suka Sari, Kecamatan Kabawetan, Kabupaten Kepahiang. Sehingga kedepannya kelompok tani dapat mengelola limbah organik secara tepat sehingga menghasilkan produk bermanfaat seperti biohandsanitizer dan biofertilizer dengan nilai jual yang tinggi dan diharapkan bisa mengurangi penggunaan pupuk kimia.
Application of Reverse Osmosis Membrane Technology in Trans Malakoni Village, Enggano Island Ashar Muda Lubis; Fachruzzaman Fachruzzaman; Rini Indriani; Sipriyadi Sipriyadi; Darmawan Ikhlas Fadli
ABDI: Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 7 No 3 (2025): Abdi: Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Labor Jurusan Sosiologi, Fakultas Ilmu Sosial, Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/abdi.v7i3.1189

Abstract

Trans Malakoni Village, located on Enggano Island, Bengkulu Province, faces significant challenges in providing access to clean, potable water. Limited access to adequate freshwater sources and water quality that frequently fails to meet health standards are major obstacles to the community's sustainable livelihood. This research aims to explore the potential and implementation of household-scale reverse osmosis (RO) technology as an innovative solution for producing clean, potable water in Trans Malakoni Village. The research methodology involves raw water quality analysis, the design of a household-scale RO system suitable for local conditions, and an evaluation of system performance and community acceptance. Initial results indicate that existing water sources in Trans Malakoni Village, although limited, can be effectively treated using RO technology to achieve established drinking water quality standards. The proposed household-scale RO system design emphasizes energy efficiency, operational ease, and affordable maintenance costs, thereby enabling sustainable adoption by households. The implementation of RO technology is expected not only to enhance access to clean water but also to contribute to improved public health, self-reliance in water resource management, and sustainable living in Malakoni Village. This study recommends further research on system optimization and community education programs to maximize the positive impact of RO technology in other remote island regions.
PENYULUHAN DAN PEMBUATAN PAPER SOAP (SABUN KERTAS) BAGI MASYARAKAT DI KELURAHAN PEMATANG GUBERNUR KOTA BENGKULU UNTUK MENINGKATKAN KESADARAN MENCUCI TANGAN SEBAGAI LANGKAH AWAL PENCEGAHAN WABAH COVID-19 Wibowo, Risky Hadi; Sipriyadi, Sipriyadi; Pertiwi, Reza; Hidayah, Thoriqul; Medani, Della Indah; Wulandari, Gustina Dwi; Rosianti, Nadya
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 4, No 1 (2021): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v4i1.317-324

Abstract

Hand is the main transmission pathogen entry into the body which is the part of the body that is most often in direct contact with other limbs and surrounding objects. The importance of maintaining hand hygiene by always washing hands with soap is the first step in preventing transmission of COVID-19. However, during a pandemic like this, it will be difficult to find soap available everywhere, and tends to be hard to carry all the time. Therefore, this service aims to invite the people of Pematang Gubernur, Bengkulu City, to use paper soap because it is easier to use its use and flexible to carry anywhere besides being an effort to prevent the COVID-19 outbreak, it can also add to new information and skills for residents in making attractive soaps. The feedback response given by the community service implementation team to the community service participants resulted in a positive response to this activity, who initially did not know about making and use of paper soap and became aware of this. 
Analysis of Mercury Concentration in Food Crops Around the Lebong Regency Gold Mine Fatimatuzzahra, Fatimatuzzahra; Sri Astuti, RR; Satriawan, Dedi; Sipriyadi, Sipriyadi; Istikhomah, Sekar; Eva Nadya Purba, Juwita; Farid Fadhlullah, Muhammad; Wahyu Nengsih, Anisa; Shofi, Muh.; Saputra, Alanindra
Biosfer: Jurnal Tadris Biologi Vol 16 No 2 (2025): Biosfer: Jurnal Tadris Biologi
Publisher : UNIVERSITAS ISLAM NEGERI RADEN INTAN LAMPUNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24042/biosfer.v16i2.29163

Abstract

This study aims to inventory the types of food crops growing around tailings ponds and to quantify mercury concentrations in food crop tissues growing in the area around the gold mine. The samples taken are plants consumed by residents. Mercury content testing uses a mercury analyzer. The results of the study showed that from 4 observation locations, a total of 11 types of food crops were found, all of which contained mercury (Hg) with a concentration range of 0.01-0.54 mg/kg. Similarly, the soil as a growing medium contains quite high levels of mercury at location 1, namely 54.36 mg/kg, and the lowest at location 3 at 0.12 mg/kg. The concentration of mercury in vegetable leaves is much higher than in other organs such as tubers, flowers, and fruits. Furthermore, to plant plants for consumption, it is best to pay attention to the condition of the growing medium, as a prevention of heavy metal (mercury) contamination, such as the environment (air, soil, water) that is far from waste retention ponds or waste discharge streams containing heavy metals (mercury). Analisis Konsentrasi Merkuri pada Tanaman Pangan di Sekitar Tambang Emas Kabupaten Lebong ABSTRAK: Penelitian ini bertujuan untuk menginventarisasi jenis tanaman pangan yang tumbuh disekitar kolam penampungan limbah (tailing) dan untuk mengkuantifikasi konsentrasi merkuri dalam jaringan tanaman pangan yang tumbuh di area sekitar tambang emas. Sampel yang diambil merupakan tanaman yang memang dikonsumsi oleh warga setempat. Uji kandungan merkuri menggunakan mercury analyzer. Hasil penelitian menunjukkan dari 4 lokasi pengamatan, ditemukkan Sebanyak 11 jenis tanaman pangan yang semuanya mengandung merkuri (Hg) dengan kisaran konsentrasi 0,01-0,11 mg/kg. Demikian pula, tanah sebagai media tanam mengandung kadar merkuri yang cukup tinggi di lokasi 1, yaitu 54,36 mg/kg, dan paling rendah dilokasi 3 sebesar 0,12 mg/kg. konsentrasi merkuri dalam daun sayuran jauh lebih tinggi dibandingkan organ lain seperti tuber, bunga, dan buah. Selanjutnya, untuk menanam tanaman yang akan dikonsumsi sebaiknya memperhatikan kondisi media tumbuh, sebagai pencegahan dari kontaminasi logam berat (merkuri), seperti lingkungan (udara, tanah,air) yang jauh dari kolam penampungan limbah maupun aliran pembuangan limbah yang mengandung merkuri.
Identifikasi dan Patogenisitas Agen Bakteri Penyebab Penyakit Busuk Batang pada Buah Naga (Hylocereus sp.) Fahmi, Riziq Ilham Nur; Cahlia, Uci; Wibowo, Risky Hadi; Sipriyadi, Sipriyadi
Spizaetus: Jurnal Biologi dan Pendidikan Biologi Vol 7 No 1 (2026): Spizaetus: Jurnal Biologi dan Pendidikan Biologi
Publisher : Program Studi Pendidikan Biologi, FKIP, Universitas Nusa Nipa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55241/spibio.v7i1.705

Abstract

The increasing intensification of dragon fruit (Hylocereus sp.) cultivation is followed by an increase in disease attacks that have the potential to reduce plant productivity. This study aims to isolate, identify, and test the pathogenicity of bacteria that cause dragon fruit stem rot in Pematang Donok Village, Kepahiang, Bengkulu. Bacterial isolation was carried out from disease-infected stem tissue, followed by isolation purification. Bacterial identification was carried out based on colony morphology and Gram staining, while pathogenicity and hemolysis tests were carried out on potatoes and blood agar media, respectively. The data were analyzed descriptively qualitatively through observation of colony morphological characteristics and Gram staining, as well as pathogenicity tests on potatoes and hemolysis tests on blood agar. The isolation results obtained two bacterial isolates, namely isolates BBNK1 and BBNK2 with different colony morphology characteristics. Both isolates are Gram-positive bacteria with bacillus and coccus cell shapes. Pathogenicity tests on potatoes showed that both isolates were able to cause soft rot symptoms such as tissue softening, discoloration, and mucus formation compared to the control. Hemolysis tests showed that only isolate BBNK1 showed hemolytic activity with the formation of a clear zone around the isolate. The findings of this study offer foundational data to support future research on molecular identification and the development of more environmentally friendly and sustainable disease management strategies.
Isolation and Screening of Soil Chitinolytic Actinobacteria as the Anti-Fungal Producer of Plant Pathogens Risky Hadi Wibowo; Sipriyadi Sipriyadi; Nisa Rachmania Mubarik; Iman Rusmana; Maggy Thenawidjaya Suhartono
Elkawnie Vol. 6 No. 2 (2020)
Publisher : Faculty of Science and Technology Universitas Islam Negeri Ar-Raniry

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22373/ekw.v6i2.7400

Abstract

Abstract: Chitinolytic actinobacteria are currently more widely used because of their ability as the biological control agents to the pathogenic fungi, especially in horticultural and plantation crops. This research was conducted to obtain isolates of chitinolytic soil actinobacteria from the rhizosphere of the rubber plant (Hevea brasiliensis) area in IPB University. Antifungal activities from these actinobacteria hopely able to inhibit the growth of plant pathogenic fungi in Vitro on chitin agar media. Fusarium oxysporum and Sclerotium rolfsii are used in the inhibition test of chitinolytic actinobacteria. The results successfully obtained 16 isolates of actinobacteria were grew on  Humic Acid Vitamin (HV) agar. It showed that six of 16 actinobacteria isolates were able to produce inhibition zones to the growth of hyphae of pathogenic fungi on potato dextrose agar (PDA). KK-15 and KK-07 isolates were able to produce the largest inhibition percentages in F. oxysporum and S. rolfsii. Based on the chitinolytic index (CI) values, KK-15 and KK-07 isolates produced CI values of 1.25 and 1.5, respectively. The morphological characteristics and Gram staining of both KK-15 and KK-07 isolates are closely relative with Streptomyces sp. Abstrak: Bakteri kitinolitik saat ini banyak diteliti karena kemampuannya sebagai agens pengendali hayati jamur patogen khususnya pada tanaman hortikultura dan perkebunan. Penelitian ini dilakukan untuk mendapatkan isolat-isolat bakteri kitinolitik asal tanah dari bagian perakaran tanaman karet (Hevea brasiliensis) di daerah perkebunan karet Institut Pertanian Bogor (IPB). Aktivitas antifungi dari bakteri ini diharapkan  mampu menghambat pertumbuhan jamur patogen tanaman secara in Vitro pada media agar-agar kitin. Fusarium oxysporum dan Sclerotium rolfsii digunakan dalam uji hambat aktinobakteri kitinolitik. Hasil penelitian memperoleh 16 isolat aktinobakteri berhasil diisolasi dengan menggunakan media agar-agar Humic Acid Vitamin (HV), dan dari 16 isolat tersebut, enam isolat mampu menghasilkan zona hambat terhadap pertumbuhan hifa dari kedua jamur patogen pada media Potato Dextrose Agar (PDA) secara in Vitro. Isolat KK-15 dan KK-07 mampu menghasilkan diameter hambatan terbesar pada jamur F. oxysporum dan S. rolfsii. Berdasarkan nilai index kitinolitik (IK), isolat KK-15 dan KK-07 menghasilkan nilai IK sebesar 1,25 dan 1,5 secara berurutan. Karakteristik morfologi dan pewarnaan Gram dari kedua isolat yaitu KK-15 dan KK-07 memiliki kedekatan dengan kelompok Streptomyces spp.
OPTIMALISASI PENGGUNAAN PANEL SURYA PADA POMPA AIR UNTUK MENDORONG KEMANDIRIAN PANGAN Yuliza, Elfi; Sipriyadi, Sipriyadi; Daratha, Novalio; Intara, Yazid Ismi; Yosmar, Siska; Irkhos, Irkhos; Yusup, Pajri; Sihombing, Yosia Pandu
JMM (Jurnal Masyarakat Mandiri) Vol 10, No 2 (2026): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v10i2.38441

Abstract

Abstrak: Desa Banjarsari memiliki lahan pertanian yang cukup luas dengan sistem pengairan bersifat tadah hujan. Di sisi lain, disekitar persawahan terdapat sungai yang dapat dimanfaatkan sebagai sumber pengairan, namun dengan posisi lebih rendah . Oleh karena itu, pada kegiatan pengabdian ini dilakukan inovasi sistem pengairan pompa air berbasis energi surya dengan tujuan penyediaan sistem pengairan berbasis energi bersih dan sosilisasi penggunaan sistem. Adapun khalayak sasaran pada kegiatan ini adalah kelompok tani dan perangkat desa yang berjumlah 20 orang. Pelaksanaan pengabdian dibagi menjadi 3 tahap yakni persiapan, pelaksanaan dan evaluasi. Tahap persiapan dilakukan penyiapan sistem di laboratorium dan diskusi pelaksanaan kegiatan dengan mitra. Pelaksanaan kegiatan dimulai dengan pemasangan sistem, sosialisasi dan pelatihan. Sedangkan tahap evaluasi dilakukan melalui kuesioner dan wawancara. Berdasarkan tahapan yang dilakukan, dihasilkan sistem pengairan berbasis pompa panel, peningkatan pengetahuan dan keahlian khalayak. Hasil kuesioner menunjukan peningkatan pengetahuan khalayak tentang pemanfaatan panel surya, dari 80% menjadi 100% setelah pelaksanaan kegiatan.Abstract: Banjarsari Village has extensive farmland irrigated by rainwater. In Additon, a river located below the rice fields offers additional irrigation potential. To optimize this resource, a solar-powered water pump irrigation system was introduced as part of a community service initiative. The project aimed to provide a clean and sustainable irrigation solution while enhancing community awareness and capacity in utilizing renewable energy technology. The program engaged 20 participants, including farmers and village officials. Activities were conducted in three stages: preparation, implementation, and evaluation. During the preparation phase, the system was assembled and tested in the laboratory, followed by coordination meetings with local partners. The implementation phase involved on-site installation, community outreach, and hands-on training for users. The evaluation phase employed questionnaires and interviews to assess outcomes. The project successfully established a functional solar-powered irrigation system and strengthened participants’ knowledge and technical skills. Questionnaire results indicated a significant increase in awareness of solar panel utilization, rising from 80% prior to the program to 100% after its completion.
Uji Aktivitas Antibakteri Ekstrak Daun Ciplukan (Physalis angulata L) Terhadap Bakteri Salmonella thypii Try Nafilah Nujjiah; Sipriyadi Sipriyadi; Suci Rahmawati; Rose Intan Perma Sari; Putri Mulia
BEST Journal (Biology Education, Sains and Technology) Vol 9, No 1 (2026): Juni 2026
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v9i1.13352

Abstract

Penyakit menular seperti demam tifoid yang disebabkan oleh bakteri Salmonella typhi masih menjadi masalah kesehatan utama karena meningkatnya kasus resistensi antibiotik. Penelitian ini bertujuan untuk mengetahui dan menganalisis potensi aktivitas antibakteri ekstrak etanol 96% daun ciplukan (Physalis angulata L.) terhadap pertumbuhan bakteri Salmonella typhii. Metode penelitian yang digunakan adalah eksperimental laboratorium dengan pengujian aktivitas antibakteri menggunakan metode difusi cakram. Sampel daun ciplukan diekstraksi dengan metode maserasi menggunakan pelarut etanol 96%. Konsentrasi ekstrak yang diuji bervariasi antara 5%, 25%, 50%, 75%, dan 100%, dengan kloramfenikol sebagai kontrol positif dan DMSO sebagai kontrol negatif. Hasil skrining fitokimia menunjukkan bahwa ekstrak etanol daun ciplukan mengandung senyawa metabolit sekunder berupa flavonoid, alkaloid, fenol, tanin, dan steroid/triterpenoid. Hasil uji aktivitas antibakteri menunjukkan bahwa seluruh konsentrasi ekstrak memiliki daya hambat terhadap Salmonella typhii. Konsentrasi 5% menghasilkan rata-rata zona hambat sebesar 2,02 mm (kategori lemah), sedangkan konsentrasi 25% menghasilkan rata-rata zona hambat sebesar 4,82 mm (kategori lemah), konsentrasi 50%, 75%, dan 100% menghasilkan zona hambat masing-masing sebesar 6,32 mm, 6,20 mm, dan 6,77 mm yang termasuk dalam kategori sedang. Diameter zona hambat cenderung meningkat seiring dengan bertambahnya konsentrasi ekstrak. Penelitian ini dapat disimpulkan bahwa, ekstrak etanol daun ciplukan memiliki aktivitas antibakteri terhadap Salmonella typhii, namun efektivitasnya masih lebih rendah dibandingkan kontrol positif kloramfenikol.
Co-Authors A. Suhandi Abdul Fiddin Abdul Rahman Singkam ACENG RUYANI Adriansyah, Aulia Agustin Zarkani Aini Nurul Alanindra Saputra Alfredi Anis Fadhila Ginting Sinisuka Amelia, Aisyah Andik Purwanto Angga Martias Anggraini, Putri Lisya Anja Meryandini Annisa Prastika Anugrah, Ratu Intan Apriza Hongko Putra Aradea Bujana Kusuma, Aradea Bujana Ardinan Pribadi Aris Tri Wahyudi Aryanti, Fepta Ashar Muda Lubis Atmaja, Vesti Yunisya Atmaja, Vestidhia Yunisya Aurora Fajria Anwari Avidlyandi, Avidlyandi Azhar, Muhamad Ilham Bastian, Muhammad Chandra Bayu Pranata, Bayu Berutu, Ali Sadikin Berutu, Mei Awbina Besly Sinuhaji Bhakti Karyadi Bhakti Karyadi Budiyanto Budiyanto Choirul Muslim CHOIRUL MUSLIM Cikita Putri Tania Tindoy Cut Kandy Safiera Daratha, Novalio Darmawan Ikhlas Fadli Darmi Darmi Debie Rizqoh Dedi Satriawan Delia Komala Sari, Delia Komala Della Indah Medani Della Indah Medani Della Indah Medani Della Indah Medani Deni Parlindungan Devi Nurhasana Dhea Amelia Sari Dian Fita Lestari Dian Fita Lestari Dian Pita Lestari Djamilah Dwi Wahyuni Ganefianti Dwi Wahyuni Ganefianti, Dwi Wahyuni Eko Risdianto Elfi Yuliza Elsi Silvia Elsi Silvia Elvira Yunita Emi Hartati Eva Nadya Purba, Juwita Fachruzzaman - Fahmi, Riziq Ilham Nur Farid Fadhlullah, Muhammad Fatimatuzzahra Fatimatuzzahra Fatimatuzzahra Fatimatuzzahra Fatimatuzzahra Gusti, Widia Gustina Dwi Wulandari Gustina Dwi Wulandari Gustina Dwi Wulandari Helmiyetti Hendri Bustamam Henny Johan Henok Siboka Onim Herawati, A. Heru Dwi Nugroho Hery Haryanto Hidayah, Thoriqul Hizkia Puspa Pertiwi Ilsan, Noor Andryan Iman Rusmana Indah Medani, Della Inggraini, Maulin Irfan Gustian Irkhos Irkhos Ismir Fahri Istikhomah, Sekar Jarulis Jarulis Jarulis Jarulis Jarulise, Jarulise Johan, H. Jumiarni, Dewi Kamilah, Santi Nurul Khairani, Ade Khairunnisa Khairunnisa Khairunnisa Kumala, Wulan Okta Lestari, Dian Fita Lestari, Dian Pita Lia Putri Maharani Lingga, Rahmad M Masrukhin Maggy Thenawidjaja Suhartono Maggy Thenawidjaya Suhartono Maggy Thenawidjaya Suhartono Manurung, Widya C. Margareth Hutasoit Marisadonna Asteria Marliza Marliza Medani, Della Indah Melda Yunita Mimi Sutrawati Mokodongan, Daniel Frikli Monika Thamara Morina Adfa Morina Adfa Muda Lubis, Ashar Muh. Shofi Muhammad Naufal Dzakwan Nabila, Bella Nadya Rosianti Nadya Rosianti Nadya Rosianti Nanang Sugianto Nisa Muhammad Thalib NISA RACHMANIA MUBARIK Novi Susianti Novianti, Reti Novriantika Lestari Noya, Erinn D. Nursaadah, Euis Oktaria Silviani Oktoviani Oktoviani, Oktoviani Oky Hermansyah Parlindungan, Deni Parwito Parwito, Parwito Permata sari, Silvia Prastya, M. Eka Priadi, Untung Priyatiningsih Purbani, Debora Christin Puspytha, Yolanda Putra, Apriza Hongko Putri Mulia Putri Rizky Lailatur Rahmah Putri, Agitha Febysanti Putri, Desy Hanisa R R. Sri Astuti R.H. Wibowo R.R.S. Astuti Rahmah, Anggi Apria Faradisya Rangga Ardiansyah Redo Setiawan Redo Setiawan Resiliani, Tiara Reza Pertiwi Reza Pertiwi Reza Wahyuni Reza Wahyuni Reza Wahyuni Ridwan Sala Rina Suthia Hayu Rindiyani, Rindiyani Rini Indriani Riska Ekawita Risky Hadi Wibowo Risky Hadi Wibowo Risky Hadi Wibowo Risky Hadi Wibowo Risky Hadi Wibowo Rizawati Rizawati Rizka Fitria Ningrum Rizwar Rochmah Supriati Rofiani, Desi Rose Intan Perma Sari Rosianti, Nadya Rothman, Dita Delia Safniyeti Sal Prima Yudha Salsabilla, Sisilia Santi Nurul Kamilah Saputri, Ika Sari, Dhea Amelia Sari, Rose Intan Perma Sariyanti, Mardhatillah Sartika Wati Dwi Sapitri Sasmita, Anggun SEMPURNA GINTING Septi Johan serly rahmadinie Setiawan, Redo SIHOMBING, YOSIA PANDU Silvia, Elsi Simanjuntak, Putri Hezekiel Claracia Sinaga, Fery Fernando Sinisuka, Alfredi Anis Fadhila Ginting Siska Yosmar Siti Nurfajriah Sitorus, Lizken Sri Astuti, RR Sri Wahyu Kurnia Putri Stella Reformanda Sembiring Suci Rahmawati Sukmawati, Sukmawati Suryani, Utari Hartati Susanti, Elia Taifur, Aghus Thamara, Monika Thoriqul Hidayah Thoriqul Hidayah Thoriqul Hidayah Trianda, Aldy Try Nafilah Nujjiah Uci Cahlia Ulandasari Ulandasari Utama, Ahmat Fakhri Vero Neka Emelda Vestidhia Yunisya Atmaja Wahyu Nengsih, Anisa Wahyuni, Reza Welly Darwis Welly Darwis Welly Darwis Welly Darwis Welly Darwis Welly Darwis Wibowo, Risky Hadi Wirahmi, Nori Wulan Okta Kumala Wulan, A. R. Wulandari, Gustina Dwi Yar Johan, Yar Yazid Ismi Intara Yenny Sariasih Yuli Febrianti YULIN LESTARI Yuni Kristina Serlyani Yusup, Pajri