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Implementasi Model Pembelajaran Kasus Unsung Cinderella pada Farmakoterapi untuk Menguatkan Kesadaran Peran Farmasi di Masyarakat Yuliawati, Yuliawati; Sani K, Fathnur; Elisma, Elisma; Pondawinata, Marizki
Panthera : Jurnal Ilmiah Pendidikan Sains dan Terapan Vol. 5 No. 4 (2025): October
Publisher : Lembaga Pendidikan, Penelitian, dan Pengabdian Kamandanu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/panthera.v5i4.747

Abstract

The role of pharmacy in healthcare services requires cognitive and affective skills, as well as strong communication abilities. However, in Indonesia, pharmacists’ involvement in direct patient care remains limited; therefore, innovative learning models are needed to foster awareness of the pharmacist’s role in society. This study aimed to implement a case-based learning model utilizing the Unsung Cinderella drama series in the Pharmacotherapy II course. The research was conducted among students of the Pharmacy Study Program, University of Jambi, during the odd semester of the 2023/2024 academic year. The method used was classroom action research, involving stages of case study implementation, group discussions, presentations, role-playing, and evaluations through questionnaires and activity documentation. The results showed that the implementation of the case-based learning model using the Unsung Cinderella series achieved an average student satisfaction rate of 80.4%, categorized as very good, and enhanced students’ understanding of the pharmacist’s role according to the Ten Star Pharmacist framework.
Construction and Expression of Immunotoxin Anti EGFRvIII scFv-HPR Conjugate in Pichia pastoris as A Targeted Drug Candidate for Cancer Therapy Yuliawati, Yuliawati; Soejoedono, Retno Damayanti; Fuad, Asrul Muhamad
Annales Bogorienses Vol. 18 No. 1 (2014): Annales Bogorienses
Publisher : BRIN

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Abstract

Epidermal growth factor receptor variant III (EGFRvIII) is a mutant of EGFR lacking 267 amino acids (exon-2 through 7) within its extracellular domain, resulting in the formation of a new epitope as a tumor specific target. EGFRvIII is commonly found in GBM, breast, ovarian, prostate, and lung carcinomas. Antibodies or part of antibodies (e.g. single chain variable fragment or scFv) with specific activity against this receptor have been developed. These antibodies are internalized into the cell after receptor binding. Ribonucleases can be cytotoxic due to their inherent ability to degrade RNA, therefore causing cell death via inhibition of protein synthesis. The aim of this research is to construct, clone and express an immunotoxin-based conjugate combining an anti-EGFRvIII scFv with a HPRmut (human pancreatic ribonuclease mutant variant) in Pichia pastoris. The anti-EGFRvIII scFv gene was cloned into yeast expression vector pPICZαA and fused with EGFP gene as a marker. The HPRmut gene was subsequently cloned at the C-terminal of the scFv::EGFP fusion, resulting in the scFv::EGFP::HPR fusion construct. The fusion construct was successfully obtained and nucleotide sequence of plasmid was verified. This construct was used to transform P. pastoris SMD 1168H. The gene fusion was successfully transformed and expressed in P. pastoris with a transformation efficiency of 102 cfu/μg DNA. The transformed yeasts were screened on agar media containing up to 1000 μg/ml zeocin. Yeast transformants showed green fluorescent due to the expression of EGFP gene. The recombinant proteins have been expressed and secreted from P. pastoris as showed by immunoblotting and SDS-PAGE analyses, then purified by affinity chromatography method. The selected yeast transformant produced at least 15.85 mg of purified protein per liter of yeast culture. 
Gastroprotective effect test of ekor naga leaves extract (Rhaphidophora pinnata (L.f) Schott) on male white rats Sani K, Fathnur; Putri, Kresentia; Elisma, Elisma; Lestari, Uce; Maharini, Indri; Yuliawati, Yuliawati
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 2 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i2.1698

Abstract

Rhaphidophora pinnata leaves are one of the herbal plants that have pharmacological effects. Previous research has shown that ekor naga leaves contain secondary metabolites with tonic pharmacological effects, including the ability to heal cut wounds, as well as antihyperglycemic and antidiabetic properties. This research aims to demonstrate the potential of ekor naga leaf extract as a gastroprotective agent. The extract was evaluated using standard methods, including determination of water content, ash content, phytochemical screening, and compound identification by LC-MS. Gastroprotective testing was carried out by dividing the treatment group into six groups, including the Group 1: normal group, Group 2: negative control (Sodium CMC 0.5%), Group 3: positive control (Sucralfate), Group 4: 125mg/KgBW extract, Group 5: 250 mg/KgBW extract, and Group 6: 500mg/KgBW extract. The results of the observations were in the form of gastric ulcer severity scores and histological images of the gastric organs. Gastroprotective testing revealed significant differences between the treatment groups and the negative control group (p<0.05). The 500 mg/kgBW extract exhibited the most effective gastroprotective effect, with a 42.5% inhibition rate and minimal inflammation observed both macroscopically and microscopically. These results suggest that ethanol extract from ekor naga leaves may serve as an alternative or complementary therapy for gastritis.
Edukasi dan Praktik: Menanam Sayur bersama Siswa Kelompok Bermain dan Taman Kanak-kanak Satya Wacana Zebua, Damara Dinda Nirmalasari; Yuliawati, Yuliawati; Sheliena, Esther; Ningrum, Priskilah Febi Widya; Jayaprawira, Jefanya Diva Adriana; Restu, Luna Yureka
Madaniya Vol. 6 No. 3 (2025)
Publisher : Pusat Studi Bahasa dan Publikasi Ilmiah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53696/27214834.1304

Abstract

Kesadaran akan pentingnya lingkungan merupakan sikap yang perlu dimiliki setiap individu termasuk anak-anak. Sikap ini perlu dipupuk sejak dini sehingga dapat menjadi kebiasaan yang baik di kemudian hari. Pengabdian masyarakat ini bertujuan untuk menumbuhkan kesadaran lingkungan, kecintaan terhadap alam, serta memberikan pengetahuan tentang cara menanam dan merawat tanaman kepada anak-anak Kelompok Bermain dan Taman Kanak-kanak. Melalui kegiatan ini, anak-anak belajar mengenai bagian-bagian tanaman dan mempraktikkan langsung penanaman bibit sayuran. Hasilnya, anak-anak menunjukkan antusiasme dan mampu mengikuti tahapan kegiatan “Planting Time” dengan baik, mulai dari mengenal bagian tanaman hingga praktik menanam bibit sayuran.
Pemberdayaan Bank Sampah Dayung Habibah melalui Edukasi dan Pembuatan Eco Enzyme serta Diversifikasi Produknya Yuliawati, Yuliawati; Kasmadi, Fathnur Sani; Maritsa, Hasnaul
Jurnal Abdimas Kesehatan (JAK) Vol. 7 No. 3 (2025): November
Publisher : Universitas Baiturrahim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36565/jak.v7i3.1013

Abstract

The increasing volume of household organic waste remains a challenge in many communities, including Legok Village, Jambi. This community engagement program aimed to enhance local residents’ knowledge and skills in organic waste management through the production of eco-enzyme and its derivative products. The methods applied included education, interactive discussions, and hands-on training in producing eco-enzyme, dishwashing soap, floor cleaner, liquid organic fertilizer, compost, and compress pads. Evaluation was conducted using pre- and post-tests to measure knowledge improvement, as well as a satisfaction survey to assess participants’ acceptance. Results showed a significant increase in knowledge, with average scores rising from 54 (pre-test) to 84 (post-test), representing a 55.5% improvement. Participants successfully followed all stages of eco-enzyme preparation, from material selection and mixing to the initial fermentation process, and demonstrated the ability to independently produce eco-enzyme and its derivatives at home. This program effectively improved environmental literacy, awareness, and motivation among the community in managing household waste. Furthermore, it created opportunities for eco-friendly entrepreneurship based on a circular economy, supporting sustainable development goals (SDGs).
PENINGKATAN KEMANDIRIAN EKONOMI IBU RUMAH TANGGA MELALUI DEMONSTRASI PEMBUATAN SABUN CUCI PIRING Andriani, Lili; Perawati, Santi; Sutrisno, Deny; Yuliawati, Yuliawati
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 3, No 1 (2020): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v3i1.95-101

Abstract

Dishwashing soap is a daily requirement of housewives. Solvents can be manufactured on a home scale using materials and methods that are easy to do.  The activity of making dish soap can increase the economic independence of mothers who are around the hallway of Mangga Besar village Wijaya Pura in Jambi Selatan, Jambi City. The method used for community service activities is through demonstration directly in front of the participants ' mothers. A total of 20 enthusiastic participants participated in the events ranging from the preparation of materials to packaging. It also examined the safety aspects of chemicals used and analysis of the price calculation of production and sales calculations.
DIVERSIFICATION OF HERBAL PRODUCTS BASED ON LOCAL WISDOM AS AN EFFORT TO PREVENT STUNTING FOR THE COMMUNITY OF OLAK KEMANG VILLAGE Kasmadi, Fathnur Sani; Maharini, Indri; Maimum, Maimum; Fitrianingsih, Fitrianingsih; Neldi, Vina; Astuti, Novia Tri; Perawati, Santi; Yuliawati, Yuliawati; Yuliandani, Yuliandani; Nurfadilah, Nurfadilah
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 2 (2025): MEDIC. Medical dedication (In Progress)
Publisher : Universitas Jambi

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Abstract

Stunting, or chronic malnutrition, remains a significant public health challenge in Indonesia, impacting the cognitive and physical development of children. This community service project aimed to address this issue through a culturally sensitive and sustainable approach in the community of Olak Kemang Village, Jambi. The program focused on diversifying local wisdom-based herbal products to improve nutritional intake among pregnant women, lactating mothers, and children under five. The method involved a three-stage process: (1) socialization and nutritional education about stunting, (2) training on the hygienic processing of local plants rich in micronutrients, such as Moringa (Moringa oleifera) and Katuk leaves (Sauropus androgynus), and (3) a hands-on workshop on creating diversified, child-friendly products like herbal powders, fortified cookies, and puddings. Pre- and post-activity questionnaires demonstrated a significant increase in participants' knowledge and awareness of stunting prevention, from 67,4% to 90,58%. Participants also successfully produced several innovative herbal food products. This initiative highlights that empowering communities by integrating local knowledge with scientific principles is a promising and effective strategy for stunting prevention. Keywords: Stunting, community service, herbal product, nutrition, local wisdom.
Co-Authors Agnes Chaprilia Agung Giri Samudra Aisyah Aisyah Alfred Jansen Sutrisno Amrina, Dania Hellin Andree Wijaya Setiawan Angga Adi Prasetya Anggia, Sonia Anggraini, Yetti Anggun Novita Sari Apriansah, Rafel Arif Irfanda Arifah Rahayu Aripin, Agung Asrul Muhamad Fuad, Asrul Muhamad Astuti, Novita Tri Athanasius Aditya Wisnu Graha Aulia Habsari Ave Olivia Rahman Baskara, Jeremia Christ Adi Bayu Nuswantara Bistok Hasiholan Simanjuntak Brata, Andy Chairun Nisa DA, Sakti Nurani Damara Dinda Nirmalasari Zebua Darudriyo, Darudriyo Desriani Desriani Dewanti, Meisya Adelina Dewi Astuti, Sakti Nurani Efendi, M. Rifki Elisa Murti Puspitaningrum Elisma Elisma Endang Pudjihartati Endang Purwati RN Eni Widiastuti, Eni Enjang Pera Irawan, Enjang Pera Fadillah, Harif Fahrudin, Saleh Faizar Farid Fasya, Abdul Hakim Zakkiy fatimah Fatimah Fauzi, Muhamad Ikmal Febyningsi Rambu Ladu Mbana Febyningsi Rambu Ladu Mbana Fernando Augusta Laksono Fina, Fina Fitrianingsih Fitrianingsih Galih Seno Samodro Giri Widakdo Gustiana, Gita Gustina Lubis Hadyantari, Faizatu Almas Hananto, Hans Handoko Handoko Hapsari, Betalini Widhi Hari Sunarto, Hari Hartati Soetjipto Hartati, Eka Yuli Harwila, Elisabeth Beta Hasan Hariri Hasnaul Maritsa Haz, Aufa Rizqia HENDRA GUNAWAN B11211055 Hidayanti, Lia Hohary, Yunelfi Musraino Ihsan, Mahya Illene Naomi Nugroho Intan Istiqomah, Intan Irvan Aji Saputra Iskandar, Mirna Marhami ISLAMIYATI Jaka Wijaya Kusuma Jannah, Zahratul Jayaprawira, Jefanya Diva Adriana Jeremia Christ Adi Baskara KASWATI KASWATI Klarista Ardiani Klarista Ardiani Kristin V Pasaribu Kumala, Ajeng Putri Lasmono Tri Sunaryanto Latipah, Siti Lili Andriani Liska Simamora Loho, Michelle Angellina Lolita Geofanny Pramono M. Arifki Zainaro M. Rifqi Efendi Maharini, Indri Maria Maria Maria Maria Maria Maria Maria Marina Herawati Marsela Anggita Ratri Martini Martini Maulida, Dafa Riska Mayasari Dwi Rahayu Mochammad Imron Awalludin Muhaimin Muhaimin Muhammad Hardika Prasetya Muhammad Mas&#039;udin Muhammad Syukri Nainggolan, Dedy Sunaryo Nani Yulianti Naryati, Naryati Natasia Alinsari Neldi, Vina Ningrum, Priskilah Febi Widya Noorohmah, Siti Novia Tri Astuti Novialno, Trias Novica, Siti Rezeki Nugraheni Widyawati Nur Rochman Nuraenah, Nuraenah Nurfadilah Nurfadilah Nurindah, Siti Oktavianus Lumban Tobing P Purwanto Pangestika, Maria Permatasari, Leni Petrus Kristriantono Pitrianti, Siti Polykarvos Nubun Pondawinata, Marizki Pratiwi, Ossy Aprillia Pratiwi, Pupa Dwi Purwantiningsih, Purwantiningsih Puspa Dwi Pratiwi Puspa Dwi Pratiwi Putra, Rizky Yulion Putri, Allisa Julia Putri, Kresentia Putri, Reza Resinta R Aji Bayu Nugroho R. Aji Bayu Nugroho Rahayu, Resa Sri Rahman, Havizur Raihan, Eldrian Daffa Raka Ega Prasetya Rantau, Deritha Ellfy Restu, Luna Yureka Retno Damayanti Soejoedono Ria Rosdiana Silaban Riska Sarofah, Riska Ristya Desy Wardani Riswanti Rini Rochman , Nur Rodhiah Umaroh Rofana Aghniya Romualdus Reinaldo Rona Romadhianti, Rona Sadiman Sadiman Sadli, Nurul Kamilah Safitri, Wita Sani K, Fathnur Santi Perawati, Santi Saputra, Irvan Aji Saputro, Sahrul Saragih, Elsa Christin Sari, Kimah Amelia Sari, Rifa Nita Saroh, Siti Setyono, Setyono Sihombing, Elsa Anggriani Sinta Nur Riskawati Siska Siska Sitti Fatimah Syahid Sri Lestariningsih Subastian, Reza Suherman, Alvianita Sulistiyorini, Dyah Nuraini Sulistyowati, Nina Suliyah Suliyah Supriadi Supriadi Suprihati Suprihati Suprihati Sutrisno , Deny Syamsurizal - - Tampubolon, Yunita Angela Tari, Yusnia Teguh Wahyono Tiara Juniar Soewardi Tinjung Mary Prihtanti Tisnasari, Sundawati Trie Venny Pratiwi Uce Lestari Utami, Diah Tri Utomo, Bayu Aji Vanika, Niken Wadu, Junaedin Wahyu Tri Utama Widiyanti, Septi Wiwi Sepriani Wulandari, Arbiana Putri Wulandari, Dyah Retno Yassar, Gina Cantica Yeni Haryani, Yeni Yoga Aji Handoko Yuliandani, Yuliandani Yuliawati Yusri Dianne Jurnalis Yustiza, Non Rachmani Yusy Kurnia Chrisdiyanti