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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan SOCA: Jurnal Sosial Ekonomi Pertanian Jurnal Sosial Ekonomi Pertanian AGRIKA JURNAL MANAJEMEN AGRIBISNIS AGRIEKONOMIKA Jurnal Agribisnis Indonesia (Journal of Indonesian Agribusiness) Jurnal Penelitian Ekonomi dan Bisnis AGRIVITA, Journal of Agricultural Science Jurnal Informatika dan Teknik Elektro Terapan Jurnal Penelitian Pertanian Terapan Mimbar Agribisnis: Jurnal Pemikiran Masyarakat Ilmiah Berwawasan Agribisnis AGRIKAN Jurnal Ilmiah Agribisnis dan Perikanan Caraka Tani: Journal of Sustainable Agriculture Jurnal SEPA (Social Economic and Agribusiness Journal) Jurnal Agribisnis Terpadu Jurnal Ekonomi dan Bisnis Jurnal SOLMA JEPA (Jurnal Ekonomi Pertanian dan Agribisnis) Dinamisia: Jurnal Pengabdian Kepada Masyarakat SEEIJ (Social Economics and Ecology International Journal) Agrisocionomics: Jurnal Sosial Ekonomi Pertanian JURNAL ILMIAH MAHASISWA AGROINFO GALUH Jurnal Ilmiah Ilmu Keperawatan Indonesia (Indonesian Nursing Scientific Journal) Martabe : Jurnal Pengabdian Kepada Masyarakat Owner : Riset dan Jurnal Akuntansi Agrilan : Jurnal Agribisnis Kepulauan JURNAL PENDIDIKAN TAMBUSAI PARAMUROBI JURNAL PERTANIAN QARDHUL HASAN: MEDIA PENGABDIAN KEPADA MASYARAKAT JURNAL AGRONIDA Jurnal Kreativitas PKM Manuju : Malahayati Nursing Journal JKM (Jurnal Kebidanan Malahayati) Jurnal Ilmu Kefarmasian Indonesia Jurnal Kesehatan Agritech: Jurnal Fakultas Pertanian Universitas Muhammadiyah Purwokerto JMD: Jurnal Riset Manajemen & Bisnis Dewantara JURNAL FARMASIMED (JFM) Asian Journal of Agriculture Kumawula: Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Kesehatan ZIRAA'AH MAJALAH ILMIAH PERTANIAN Media Agribisnis Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Jurnal Peduli Masyarakat Jurnal Samudra Ekonomika Madaniya JURPIKAT (Jurnal Pengabdian Kepada Masyarakat) MEDIC MEdical Dedication SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Journal of Health Community Service Jurnal Bio-Geo Material Dan Energi Al-Mu'awanah Unram Journal of Community Service (UJCS) Edusoshum: Jurnal Pendidikan Islam dan Sosial Humaniora Jurnal Salam Sehat Masyarakat (JSSM) PREDIKSI (Profesi Pendidikan Indonesia) Al Fiddhoh: Journal of Banking, Insurance, and Finance Journal of International Conference Proceedings Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Jurnal Hibrul Ulama Sciences of Pharmacy Jurnal Penelitian Ilmu Pendidikan Indonesia Journal of Hospital Management Panthera : Jurnal Ilmiah Pendidikan Sains dan Terapan EJOIN : Jurnal Pengabdian Masyarakat Riset Informasi Kesehatan Jurnal Pendidikan Terapan Jurnal Pengabdian Harapan Ibu (JPHI) Jurnal AGRISEP: Kajian Masalah Sosial Ekonomi Pertanian dan Agribisnis Journal of Pharmaceutical and Sciences. Jurnal Manusia dan Lingkungan AGRIC Jurnal Kesehatan Metro Sai Wawai Indonesian Journal of Community Empowerment Borneo Journal of Pharmacy Jurnal Abdimas Kesehatan Growth: Journal Management and Business Annales Bogorienses
Yuliawati
Universitas Kristen Satya Wacana
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Karakteristik dan Pengetahuan Pasien dalam Perawatan Luka Pasca Operasi di Rumah Sakit Islam Jakarta Naryati, Naryati; Aisyah, Aisyah; Widakdo, Giri; Nuraenah, Nuraenah; Fatimah, Fatimah; Zainaro, M. Arifki; Dewanti, Meisya Adelina; Apriansah, Rafel; Hartati, Eka Yuli; Yuliawati, Yuliawati
Malahayati Nursing Journal Vol 7, No 3 (2025): Volume 7 Nomor 3 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i3.19374

Abstract

ABSTRACT The problem of Surgical Site Infection (SSI) is a problem that may occur due to surgical procedures, it can affect various layers of body tissue, superficial or deep. The incidence of SSI at the Jakarta Islamic Hospital in 2023 reached 16 incidents. This study aims to identify the characteristics and knowledge of patients in post-operative wound care at the Jakarta Islamic Hospital. The research method that will be carried out is simple descriptive with a cross-sectional approach. The results of the study explain that; all respondents totaling 31 respondents who have BPJS as their health insurance, the majority are female 96.8%, the distribution of indications for CS surgery in patients with SSI without indication reaches a proportion of 16.1%, KPD 16.1%, patients with comorbidities DM, hypokalemia, pulmonary TB, thrombocytopenia, and PEB each amounting to 1 person, the majority of patients' childbirth history is the first delivery of 54.2%, patient knowledge about wound care is obtained 25.8%, efforts to seek help are obtained results 83.3%, information needed by patients with SSI is obtained results 6.5% need information about wound care, 9.7. These findings indicate the importance of early education and information/continuous discharge planning with health centers or families in order to increase knowledge in an effort to reduce the risk of infection problems that occur Keywords: Characteristics, knowledge, wound care, Post-Operation ABSTRAK Masalah Infeksi Daerah Operasi (IDO) merupakan masalah yang mungkin terjadi akibat tindakan pembedahan, dapat mengenai berbagai lapisan jaringan tubuh, superfisial atau dalam. Kejadian IDO di Rumah Sakit Islam Jakarta tahun 2023 mencapai 16 kali kejadian. Penelitian ini bertujuan mengidentifikasi karakteristik dan pengetahuan pasien dalam perawatan luka pasca operasi di Rumah Sakit Islam Jakarta. Metode penelitian yang akan dilakukan  dengan deskriptif sederhana dengan pendekatan crossectional. Hasil penelitian menjelaskan bahwa; seluruh responden berjumlah 31 responden yang memiliki BPJS sebagai jaminan kesehatannya, mayoritas berjenis kelamin perempuan 96,8 % , sebaran  indikasi operasi SC pada pasien dengan IDO tanpa indikasi mencapai proporsi 16,1 %  , KPD 16,1% , pasien dengan penyakit penyerta DM, hipokalemi, Tb paru, trombositopenia, dan PEB masing-masing berjumlah 1 orang, riwayat persalinan mayoritas pasien persalinan pertama sebanyak 54,2%  , pengetahuan pasien tentang perawatan luka didapatkan 25,8%, upaya mencari pertolongan didapatkan hasil 83,3%, informasi yang dibutuhkan pasien dengan IDO didapatkan hasil 6,5% membutuhkan informasi tentang perawatan luka, 9,7%. Temuan ini menunjukkan pentingnya edukasi  dini dan informasi/ discharge planning berkelanjutan dengan puskesmas atau keluarga guna meningkatkan pengetahuan dalam upaya mengurangi resiko  masalah infeksi yang terjadi Kata Kunci: Karakteristik, Pengetahuan, Perawatan Luka,Pasca Operasi
Formulation and evaluation of soap preparations from Curcuma zedoaria rhizome Yuliawati, Yuliawati; maimum, Maimum; Iskandar, Mirna Marhami; Sani, Fathnur
Riset Informasi Kesehatan Vol 13 No 2 (2024): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v13i2.910

Abstract

Background: Maintaining skin cleanliness is one of the effective ways to maintain the health of the body caused by infections caused by microorganisms. A simple way to maintain skin cleanliness is to clean the skin using soap. Soap functions to clean dirt and can inhibit pathogens found on the surface of the epidermis. The purpose of this study is to determine the effect of different concentrations of white temu rhizome infusion on solid soap preparations Method: this study is experimental. The difference in the concentration of active ingredients in the infusion of white rhizomes was 0%, 5%, 7.5%, and 10%. The process of making infusions starts from making simplicia powder. The preparation tests carried out are organoleptic testing, pH test, foam height test and foam stability. Results: the results of the study showed that the amount of simplicia powder obtained was 535.1 grams with a percentage of simplicia yield of 17.40%. The results of the characteristic evaluation were obtained in the organoleptic test of the color of the difference influenced by the difference in the concentration of the added infusion. The results of the pH test of the solid soap formula of the white temu rhizome infusion meet the set standards, namely with a pH value between 9.27 – 9.87 so that it is safe to use on the skin. Conclusion: Based on the research conducted, it can be concluded that the infusion of rhizome of Curcuma zedoaria can be formulated into preparations in the form of solid soap and the difference in the concentration of infusion of curcuma has an influence on organoleptic testing, pH, and foam height as well as foam stability.
Botol Ajaib: Memproduksi Sayuran Segar dari Sampah Plastik Bayu Nuswantara; Damara Dinda Nirmalasari Zebua; Yuliawati Yuliawati; Esther Sheliena; Tinjung Mary Prihtanti; Maria Maria; Lasmono Tri Sunaryanto; Klarista Ardiani; R. Aji Bayu Nugroho
Madaniya Vol. 6 No. 1 (2025)
Publisher : Pusat Studi Bahasa dan Publikasi Ilmiah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53696/27214834.1077

Abstract

Upaya untuk menjaga lingkungan di sekitar kita adalah tanggung jawab bersama yang harus terus diusahakan. Hal ini memerlukan kesadaran dari setiap individu yang kemudian perlu diwujudkan dalam bentuk tindakan nyata. Tujuan dari kegiatan pengabdian masyarakat ini adalah meningkatkan kesadaran siswa SD Kanisius Gendongan untuk peka terhadap lingkungan sekitar dengan memanfaatkan sampah plastik melalui praktik pertanian secara hidroponik. Pelaksanaan kegiatan diawali dengan penyuluhan untuk memberikan pemahaman pentingnya mengelola sampah plastik, dilanjutkan dengan demonstrasi dan praktik langsung oleh peserta kegiatan didampingi dosen dan mahasiswa. Kegiatan ini diikuti oleh 39 siswa kelas IV dan V yang dibagi ke dalam 8 kelompok. Setiap peserta diberikan kesempatan untuk praktik menanam bibit sayuran secara hidroponik menggunakan botol plastik bekas yang telah disiapkan. Nutrisi yang digunakan untuk memenuhi kebutuhan tanaman adalah pupuk cair (AB Mix). Manfaat yang diperoleh dari kegiatan pengabdian masyarakat ini adalah setiap peserta memiliki pengetahuan dan keterampilan dalam mengelola dan memanfaatkan sampah plastik khususnya botol plastik bekas menjadi sesuatu yang lebih berguna.
PROMOSI KESEHATAN TENTANG ANEMIA PADA IBU HAMIL DI POS KESEHATAN KELURAHAN IRINGMULYO, KOTA METRO, LAMPUNG Sadiman, Sadiman; Yuliawati, Yuliawati
EJOIN : Jurnal Pengabdian Masyarakat Vol. 2 No. 5 (2024): EJOIN : Jurnal Pengabdian Masyarakat, Mei 2024
Publisher : LPPM Institut Pendidikan Nusantara Global

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55681/ejoin.v2i5.2829

Abstract

Anemia merupakan masalah gizi yang perlu mendapat perhatian dan menjadi salah satu masalah kesehatan masyarakat Indonesia yang dapat di alami oleh semua kelompok umur mulai dari balita, remaja, ibu hamil, sampai usia lanjut. Anemia disebabkan oleh berbagai hal antara lain defisiensi zat besi, defisiensi vitamin B12, defisiensi asam folat, penyakit infeksi, faktor bawaan dan pendarahan. World Health Organization memperkirakan bahwa 40% wanita hamil di seluruh dunia menderita anemia pada tahun 2022. Sekitar 32 juta ibu hamil menderita anemia secara global, dengan persentase 27% pada regio Asia Tenggara. Berdasarkan data Riset Kesehatan Dasar (Riskesdas) 2018, prevalensi anemia defisiensi besi (ADB) pada ibu hamil di Indonesia adalah 48,9%, dimana terdapat peningkatan 11,8% jika dibandingkan dengan tahun 2013.9. Keadaan ini menunjukkan bahwa prevalensi anemia di Indonesia cukup tinggi, menunjukkan angka yang mendekati masalah kesehatan masyarakat yang serius, dengan prevalensi anemia melebihi 40%. Provinsi Lampung juga tidak terlepas dari masalah anemia pada ibu hamil. Berdasarkan data dari Dinas Kesehatan Provinsi Lampung, prevalensi anemia pada ibu hamil di provinsi tersebut masih cukup tinggi. Pada tahun 2019, prevalensi anemia mencapai 9,06% dan mengalami peningkatan menjadi 9,10% pada tahun 2020. Studi Pendahuluan pada ibu hamil di Kota Metro tahun 2019, dari 138 Ibu hamil, meliputi 46 orang berada pada kelompok mengalami anemia. Hasil penyuluhan yang telah dilakukan diketahui bahwa nilai pretest terendah dengan rata rata nilai = 51,1. Sedangkan nilai postest terendah  dengan nilai rata-rata 73,3 . Sedang rata-rata kenaikan nilai dari pretest ke postest sebesar 22,2.
Early Nutrition and Stunting: Why are Exclusive Breastfeeding and Complementary Feeding Essential for Optimal Growth? Yuliawati, Yuliawati; Lestariningsih, Sri; Anggraini, Yetti; Aghniya, Rofana; Yustiza, Non Rachmani
Jurnal Kesehatan Vol 16 No 1 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i1.4951

Abstract

This study investigates the relationship between exclusive breastfeeding, appropriate complementary feeding, and the incidence of stunting in toddlers. The objective is to identify how these nutritional practices impact child growth and development. A cross-sectional analysis was conducted involving 135 toddlers at Puskesmas Yosomulyo, utilizing a combination of interviews and questionnaires to gather data on feeding practices and health outcomes. The findings reveal that toddlers who received exclusive breastfeeding and appropriate complementary foods exhibited significantly lower rates of stunting compared to those who did not. Specifically, 33% of toddlers who were not exclusively breastfed experienced stunting, while only 19 toddlers who received appropriate complementary food were stunted. The results underscore the critical role of proper nutrition in early childhood development and highlight the need for enhanced educational programs for parents regarding feeding practices. In conclusion, promoting exclusive breastfeeding and appropriate complementary feeding is essential for reducing stunting rates and improving overall child health
Demonstrasi pengolahan herbal berkhasiat sebagai imunomodulator: Demonstrasi pengolahan herbal berkhasiat sebagai imunomodulator Perawati, Santi; Pratiwi, Puspa Dwi; Pondawinata, Marizki; Sadli, Nurul Kamilah; Neldi, Vina; Astuti, Novia Tri; Yuliawati, Yuliawati
Jurnal Pengabdian Harapan Ibu (JPHI) Vol. 7 No. 2 (2025): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/jphi.v7i2.1040

Abstract

Kegiatan pengabdian masyarakat ini dilaksanakan di Kelurahan Legok, Kota Jambi dengan tujuan meningkatkan pengetahuan dan keterampilan masyarakat dalam pengolahan tanaman herbal berkhasiat sebagai peningkat sistem imun tubuh. Metode yang digunakan berupa sosialisasi dan demonstrasi langsung pembuatan minuman herbal dari bahan lokal seperti jahe, kunyit, serai, nanas, timun, lemon, dan chia seed. Hasil kegiatan menunjukkan partisipasi aktif dari masyarakat dengan peningkatan pemahaman tentang manfaat herbal dan kemampuan praktik pengolahan ramuan herbal yang mudah diterapkan di rumah. Selain itu, kegiatan ini juga menumbuhkan kesadaran pentingnya menjaga daya tahan tubuh secara alami, terutama di masa pandemi. Kegiatan ini memberikan kontribusi dalam memberdayakan masyarakat untuk memanfaatkan sumber daya alam lokal secara optimal dan berkelanjutan sebagai upaya peningkatan kesehatan. Pengembangan lanjutan disarankan berupa pelatihan produksi minuman herbal instan dan pendampingan budidaya tanaman herbal agar manfaatnya dapat dirasakan secara luas.
Analysis of Antioxidant Potential of Infusion from Variations in Particle Size of Cinnamon Leaves Simplicia (Cinnamomum burmannii) using the DPPH Method Kasmadi, Fathnur Sani; Maulida, Dafa Riska; Jannah, Zahratul; Yuliawati, Yuliawati
Jurnal FARMASIMED (JFM) Vol 7 No 2 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i2.2455

Abstract

Background: The Cinnamon plant is used as herbal therapy and spices for cooking food in Indonesia. The content of secondary metabolite compounds has the potential as an antioxidant. Variations in particle size have been proven to have the potential to attract compounds from herbal plants. Purpose: The research aimed to determine the antioxidant potential of cinnamon leaf infusion with different simplicia particle sizes. Method: The research method used in this research was the DPPH method, using Vitamin C as a comparison, and the concentration of simplicia used to make the infusion is 5%. Result: The test results showed that a 5% infusion of simplicia microparticles had higher antioxidants than simplicia infusion with an IC50 value of 74.89 ppm, which was included in the classification of strong antioxidant activity. In contrast, the IC50 value of simplicia infusion was 110.61 ppm, which was classified as moderate. Conclusion: The infusion of simplicia microparticles from cinnamon leaves can be developed as an alternative antioxidant from natural ingredients.
TRAINING ON HERBAL MEDICINE PROCESSING FOR DEGENERATIVE DISEASES AMONG THE ANAK DALAM TRIBE (SAD) COMMUNITY IN PELEMPANG VILLAGE Kasmadi, Fathnur Sani; Efendi, M. Rifki; Maharini, Indri; Yuliawati, Yuliawati; Lestari, Uce; Perawati, Santi; Neldi, Vina; Astuti, Novia Tri
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT The Anak Dalam tribe is an indigenous tribe whose life is still primitive. This minority tribe currently inhabits the provinces of Jambi and South Sumatra. They are known by various names such as jungle people, ulu people, Anak Dalam tribe, and Kubu tribe. Their distance from the outside environment leads them to primarily utilize natural materials for their daily needs, including food and medicinal purposes. This community service activity was conducted in three stages: preparation and permit acquisition, implementation, and evaluation. The activity results demonstrated an improvement in knowledge regarding processing medicinal plants into herbal products. A total of 27 participants attended this activity, showing an improvement in knowledge from 33.33% to 88.89%. Keywords: Herbal Medicine, SAD, Degenerative, Community, Pelempang   ABSTRAK Suku anak dalam merupakan salah satu suku asli yang kehidupannya masih primitif. Suku ini menjadi suku minoritas yang saat ini masih mendiami wilayah provinsi Jambi dan Sumatera Selatan. Mereka dikenal dengan sebutan orang rimba, orang ulu, suku anak dalam, suku kubu. Jarak mereka yang cukup jauh dari lingkungan luar membuat mereka hidup lebih memanfaatkan bahan alam sebagai sarana pemenuhan kebutuhan hidup mulai dari makanan hingga untuk medis. Kegiatan pengabdian masyarakat ini dilakukan dengan 3 tahapan yaitu izin kegiatan persiapan, pelaksanaan dan evaluasi. Hasil kegiatan didapatkan adanya perbaikan pengetahuan cara pengolahan tanaman obat menjadi bentuk produk jamu. Kegiatan ini diikuti sebanyak 27 orang partisipant dengan perbaikan pengetahuan dari 33,33% menjadi 88,89%. Kata kunci: Jamu, SAD, Degeneratif, Masyarakat, Pelempang lebih memanfaatkan bahan alam sebagai sarana pemenuhan kebutuhan hidup mulai dari makanan hingga untuk medis. Kegiatan pengabdian masyarakat ini dilakukan dengan 3 tahapan yaitu izin kegiatan persiapan, pelaksanaan dan evaluasi. Hasil kegiatan didapatkan adanya perbaikan pengetahuan cara pengolahan tanaman obat menjadi bentuk produk jamu. Kegiatan ini diikuti sebanyak 27 orang partisipant dengan perbaikan pengetahuan dari 33,33% menjadi 88,89%.
INNOVATION OF DEODORANT STICKS AND LOTIONS BASED ON BETEL NUT EXTRACT AS AN ANTIBACTERIAL PROBLEM OF BODY ODOR AGAINST STAPHYLOCOCCUS AUREUS BACTERIA Tari, Yusnia; Sihombing, Elsa Anggriani; Maimum, Maimum; Efendi, M Rifqi; Pratiwi, Pupa Dwi; Yuliawati, Yuliawati; Haryani, Yeni
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol. 6 No. 02 (2025): HERCLIPS VOL 06 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v6i02.9625

Abstract

Body odor is a common problem caused by the interaction between sweat and Staphylococcus aureus bacteria. Areca nut has potential as a pharmaceutical preparation because it contains secondary metabolite compounds such as alkaloids, flavonoids, tannins, saponins and polyphenols which have antibacterial properties. This research aims to extract areca nut seeds using the maceration method with 96% ethanol and formulate them into stick deodorant and lotion with a concentration of 5%. Physical properties tests were carried out to evaluate pH, homogeneity, spreadability, melting point and antibacterial activity. The research results showed that stick deodorant had a pH of 4.5, while lotion deodorant had a pH of 5.5. Both preparations showed good homogeneity without the presence of coarse particles. The spreadability of the lotion was recorded at 5.3 cm, increasing to 5.5 cm with the addition of a 50 gram load. The melting point of bar deodoran is around 80°C, and bar deodorant melts completely within 60 minutes at 100°C. Both types of deodorant showed a significant inhibition zone diameter against bacteria, namely 18.16 mm for lotion and 16.77 mm for stiks. Areca nut extract showed very strong antibacterial activity with an inhibition zone diameter of 20.14 mm.
Wound Healing Activity of Gel Nanoparticles of Rhaphidophora pinnnata Leaves Extract in Male Rats Kasmadi, Fathnur Sani; Rahman, Ave Olivia; Rahman, Havizur; Yuliawati, Yuliawati; Samudra, Agung Giri
Borneo Journal of Pharmacy Vol. 8 No. 2 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i2.7525

Abstract

Rhaphidophora pinnata, a plant traditionally recognized for its wound-healing properties, contains active compounds such as megastigmane glycosides and damascenone, known for their anti-inflammatory effects. To enhance efficacy and user comfort, this study focused on developing an R. pinnata leaf extract nanoparticle gel. Previous research from our group highlighted the significant wound-healing potential of a conventional R. pinnata gel. This present study aimed to evaluate the wound-healing efficacy of a novel R. pinnata nanoparticle gel in male Wistar rats, specifically investigating the impact of nanotechnology application. Nanoparticles were successfully formulated via the ionic gelation method, utilizing 0.250 g of R. pinnata extract, 0.1% chitosan, 0.2% sodium tripolyphosphate, and 0.5% Tween 80. Characterization revealed an average nanoparticle size of 165.70±42.76 nm with a zeta potential of 22.0±1.83 mV. The wound-healing efficacy was assessed across five treatment groups: a positive control (Bioplasenton®), a plain gel base (Formula 0), and nanoparticle gels at 0.5% (Formula I), 1% (Formula II), and 1.5% (Formula III) extract concentrations. Statistical analysis using one-way ANOVA (p <0.05) demonstrated a significant difference in incision wound healing across the groups. Formula III, containing 1.5% R. pinnata nanoparticle extract, exhibited the most superior wound-healing effect, achieving 100% inhibition by day 14, elevated hydroxyproline levels (59 µg/mL), and histologically confirmed excellent skin tissue repair. Formulas II and I followed in efficacy. These compelling findings underscore the significant potential of utilizing nanotechnology in the development of topical preparations for accelerated and effective wound healing.
Co-Authors Afryandes, Amelya Agnes Chaprilia Agung Giri Samudra Agus Rofi’i Ahmad Khori Aisyah Aisyah Alfred Jansen Sutrisno Amrina, Dania Hellin Andree Wijaya Setiawan Angga Adi Prasetya Anggia, Sonia Anggraini, Yetti Anggun Novita Sari Apriansah, Rafel Aprilia, Sukma Ayu Arif Irfanda Arifah Rahayu Aripin, Agung Asrul Muhamad Fuad, Asrul Muhamad Astuti, Novita Tri Athanasius Aditya Wisnu Graha Aulia Habsari Ave Olivia Rahman Bachrudin Musthafa Baskara, Jeremia Christ Adi Bayu Nuswantara Bistok Hasiholan Simanjuntak Brata, Andy Butar Butar, Marta Chairun Nisa Chandra, Yuddy DA, Sakti Nurani Dadang Sunendar Damara Dinda Nirmalasari Zebua Darudriyo, Darudriyo Desriani Desriani Dewanti, Meisya Adelina Dewi Astuti, Sakti Nurani Dewi, Dinda Arum Carolina dewi, hasna Dewi, Jevan Aulia Kusuma Efendi, M. Rifki Elisa Murti Puspitaningrum Elisma Elisma Endang Pudjihartati Endang Purwati RN Eni Widiastuti, Eni Enjang Pera Irawan, Enjang Pera Fadhillah, Harif Fadillah, Harif Fahrudin, Saleh Faizar Farid Fasya, Abdul Hakim Zakkiy fatimah Fatimah Fauzi, Muhamad Ikmal Febriyanto, Budi Febriyanto Febyani, Nanda Febyningsi Rambu Ladu Mbana Febyningsi Rambu Ladu Mbana Fernando Augusta Laksono Fina, Fina Fitrianingsih Fitrianingsih Galih Seno Samodro Giri Widakdo Gustiana, Gita Gustina Lubis Hadyantari, Faizatu Almas Halim, Rd Hananto, Hans Handoko Handoko Hapsari, Betalini Widhi Harahap, Hotni Sari Hari Sunarto, Hari Hartati Soetjipto Hartati, Eka Yuli Harwila, Elisabeth Beta Hasan Hariri Hasnaul Maritsa Haz, Aufa Rizqia HENDRA GUNAWAN B11211055 Hidayanti, Lia Hohary, Yunelfi Musraino Ihsan, Mahya Illene Naomi Nugroho Intan Istiqomah, Intan Irvan Aji Saputra Iskandar, Mirna Marhami ISLAMIYATI Jaka Wijaya Kusuma Jannah, Zahratul Jayaprawira, Jefanya Diva Adriana Jeremia Christ Adi Baskara KASWATI KASWATI Klarista Ardiani Klarista Ardiani Kristin V Pasaribu Kumala, Ajeng Putri Lasmono Tri Sunaryanto Latipah, Siti Lili Andriani Liska Simamora Loho, Michelle Angellina Lolita Geofanny Pramono M. Arifki Zainaro M. Rifqi Efendi Maharini, Indri Maria Maria Maria Maria Maria Maria Maria Marina Herawati Marsela Anggita Ratri Martini Martini Maulida, Dafa Riska Mayasari Dwi Rahayu Mochammad Imron Awalludin Muhaimin Muhaimin Muhammad Hadi Muhammad Hardika Prasetya Muhammad Mas&#039;udin Muhammad Syukri Nahraeni, Wini Nainggolan, Dedy Sunaryo Najwa, Syifa Auliya Nani Yulianti Naryati, Naryati Natasia Alinsari Neldi, Vina Ningrum, Priskilah Febi Widya Noorohmah, Siti Novia Tri Astuti Novialno, Trias Novica, Siti Rezeki Novitasari, Prihatini Dini Nugraheni Widyawati Nur Rochman Nuraenah, Nuraenah Nurfadilah Nurfadilah Nurindah, Siti Oktavianus Lumban Tobing P Purwanto Pangestika, Maria Permatasari, Leni Petrus Kristriantono Pitrianti, Siti Polykarvos Nubun Pondawinata, Marizki Pratiwi, Ossy Aprillia Pratiwi, Pupa Dwi Purwantiningsih, Purwantiningsih Puspa Dwi Pratiwi Puspa Dwi Pratiwi Puteri, Vanya Gita Putra, Rizky Yulion Putri, Allisa Julia Putri, Kresentia Putri, Reza Resinta Qulyubi, M.Mujib R Aji Bayu Nugroho R. Aji Bayu Nugroho Rahayu, Resa Sri Rahman, Havizur Raihan, Eldrian Daffa Raka Ega Prasetya Rantau, Deritha Ellfy Restu, Luna Yureka Retno Damayanti Soejoedono Reza Subastian Ria Rosdiana Silaban Riska Sarofah, Riska Ristya Desy Wardani Riswanti Rini Rochman , Nur Rodhiah Umaroh Rofana Aghniya Romualdus Reinaldo Rona Romadhianti, Rona Sadiman Sadiman Sadita, Nabila Rachma Sadli, Nurul Kamilah Safitri, Wita Sani K, Fathnur Santi Perawati, Santi Saputra, Irvan Aji Saputro, Sahrul Saragih, Elsa Christin Sari, Kimah Amelia Sari, Rifa Nita Saroh, Siti Setyono, Setyono Sihombing, Elsa Anggriani Sinaga, Apri Gunawan Sinta Nur Riskawati Siska Siska Sitti Fatimah Syahid Sri Lestariningsih Suherman, Alvianita Sulistiyorini, Dyah Nuraini Sulistyowati, Nina Suliyah Suliyah Supriadi Supriadi Suprihati Suprihati Suprihati Supyan, Agus Gustapul Susi Widiawati, Susi Sutrisno , Deny Syamsurizal - - Tampubolon, Yunita Angela Tari, Yusnia Teguh Wahyono Tiara Juniar Soewardi Tinjung Mary Prihtanti Tisnasari, Sundawati Trie Venny Pratiwi Uce Lestari Utama, Putra Bhakti Satria Utami, Diah Tri Utomo, Bayu Aji Vanika, Niken Wadu, Junaedin Wahyu Tri Utama Widiyanti, Septi Wiwi Sepriani Wulandari, Arbiana Putri Wulandari, Dyah Retno Yassar, Gina Cantica Yeni Haryani, Yeni Yoga Aji Handoko Yuliandani, Yuliandani Yuliawati Yusri Dianne Jurnalis Yustiza, Non Rachmani Yusy Kurnia Chrisdiyanti