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All Journal PHARMACON Biology, Medicine, & Natural Product Chemistry Journal of Islamic Pharmacy Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Jurnal Inovasi Farmasi Indonesia Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat HERBAPHARMA : Journal of Herb Farmacological Borneo Journal Of Pharmascientech Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Abdimas Ilmiah Citra Bakti (JAICB) Jurnal Mandala Pengabdian Masyarakat Well Being Jurnal EduHealth PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID) Jurnal Ilmiah STIKES Yarsi Mataram Jurnal Lentera International Journal of Science and Environment Journal of Engineering Science and Technology Management Business and Economic Publication Jurnal Ilmiah Multidisiplin Indonesia Komunita: Jurnal Pengabdian dan Pemberdayaan Masyarakat Jurnal Media Akademik (JMA) Assoeltan: Indonesian Journal of Community Research and Engagement Contemporary Journal of Applied Sciences (CJAS) International Journal of Global Sustainable Research Indonesian Journal of Community Empowerment Jurnal Intelek Dan Cendikiawan Nusantara Jurnal Penelitian Sains dan Kesehatan Avicenna IJF (Indonesia Jurnal Farmasi) Journal of Social Science and Multidisciplinary Analysis Jurnal Intelek Insan Cendikia SEARCH: Science Education Research Gotong Royong Jurnal Pengabdian Kepada Masyarakat Al-Amin Interaksi : Jurnal Pengabdian Kepada Masyarakat Jurnal Informatika dan Kesehatan International Journal of Contemporary Sciences (IJCS) Jurnal Bioteknologi & Biosains Indonesia (JBBI) Khidmah Nusantara Jurnal Ilmu Kesehatan Jurnal Cendekia Ilmiah Joong-Ki Amaluna: Jurnal Pengabdian Masyarakat Galen: Jurnal Ilmu Farmasi dan Kesehatan Journal Health of Indonesian HelFin Journal Multicore International Journal of Multidisciplinary (MIJM) International Journal of Science and Society (IJSS) Jurnal Kajian dan Inovasi Ilmu (JKII) Mitra Jurnal Pengabdian Masyarakat Multidisiplin (MJPMM) JES-TM Social and Community Service Abdimas Paspama Jurnal Bioteknologi & Biosains Indonesia Indonesian Pharmacopeia Journal (IPJ)
Fendy Prasetyawan
Prodi Pendidikan Profesi Apoteker, Fakultas Ilmu Kesehatan, Universitas Kadiri
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Socialization of the Level of Public Awareness and Knowledge about the Benefits of Kombucha Tea in Overcoming Sleep Paralysis During the COVID-19 Pandemic Yuneka Saristiana; Fendy Prasetyawan; Chadra Arifin; Widhi Astutik; Wahyu Ariawan; Achmad Wahdi
Abdimas Paspama Vol. 2 No. 1 (2023): Abdimas Paspama, December 2023
Publisher : Abdimas Paspama

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The COVID-19 pandemic has profoundly impacted global public health, prompting a heightened focus on both physical and mental well-being worldwide. In this uncertain landscape, sleep paralysis has emerged as a notable health concern, characterized by the inability to move or speak upon waking or falling asleep, often accompanied by distressing hallucinations. With stress levels on the rise during the pandemic, cases of sleep paralysis have shown an upward trend. Conversely, probiotic beverages like kombucha tea have garnered attention for their potential health benefits, including digestive improvement, enhanced energy levels, and better sleep quality. Despite these benefits, public awareness regarding kombucha tea's efficacy in addressing sleep paralysis remains limited.To address this knowledge gap, a community service program has been developed to educate the public about kombucha tea's potential in managing sleep paralysis amidst the COVID-19 pandemic. The program involves collaboration with local communities, health institutions, and experts in mental health and nutrition. Scheduled for January 2021, the program will be executed across various locations, engaging community members and fostering dialogue on sleep health and nutrition. Preliminary results indicate a significant improvement in public understanding of sleep paralysis and kombucha tea benefits post-program. Participants exhibited heightened awareness of symptoms, causes, and treatment options for sleep paralysis, as well as a better grasp of kombucha tea's health advantages. Practical workshops on kombucha tea preparation garnered considerable interest, signaling a potential shift towards healthier lifestyle choices among participants.
PREVENTION OF GASTROPROTECTIVE ACTIVITY OF CHINESE BETEL EXTRACT (PEPEROMIA PELLUCIDA L.) ON THE HISTOPATHOLOGICAL FEATURES OF THE STOMACH IN A MOUSE MODEL OF GASTROENTERITIS Savitri, Lisa; Prasetyawan, Fendy; Saristiana, Yuneka; Juwita, Syntia Tanu; Amanda, Cornelia; Mebung, Konradus Klala
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.8156

Abstract

Gastroenteritis is a common gastrointestinal disorder characterized by inflammation of the stomach and small intestine, often leading to symptoms such as diarrhea, vomit-ing, and abdominal pain. This study investigates the gastroprotective effects of Pepe-romia pellucida (Chinese betel) extract on histopathological features of the stomach in a mouse model of gastroenteritis. Male Swiss strain mice, aged 2-3 months, were treated with different doses of P. pellucida extract (100, 300, and 500 mg/kg BW) for 7 days after inducing gastroenteritis with Escherichia coli infection. Histopathological ex-amination showed that the extract significantly reduced cell degeneration, necrosis, and polymorphonuclear leukocyte infiltration in the stomach compared to the negative control group. The highest dose (500 mg/kg BW) exhibited the most prominent gastro-protective effect. These results suggest that P. pellucida possesses promising thera-peutic potential for gastroenteritis, possibly due to its bioactive compounds such as flavonoids, tannins, and saponins. Further studies are needed to explore the underly-ing mechanisms and optimize its therapeutic application.
THE ANTI-APOPTOTIC POTENTIAL OF Paederia foetida L. LEAF EXTRACT THROUGH THE DOWNREGULATION OF CASPASE-3 EXPRESSION IN AN ESCHERICHIA COLI-INDUCED SEPSIS MICE MODEL Savitri, Lisa; Krissanjaya, Rochmad; Juwita, Syntia Tanu; Sukmawati, Datin An Nisa; Probosiwi, Neni; Laili, Nur Fahma; Ilmi, Tsamrotul; Prasetyawan, Fendy
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.8235

Abstract

Sepsis is a life-threatening condition characterized by an abnormal immune response to infection, leading to high mortality rates in intensive care units (ICUs) worldwide. Caspase-3, a crucial enzyme in the apoptosis pathway, plays a significant role in sep-sis-related cellular damage. This study investigates the anti-apoptotic potential of Paederia foetida L. leaf extract by examining its effect on Caspase-3 expression in an Escherichia coli-induced sepsis mice model. Male Balb/c mice were divided into six groups, including positive control, negative control, and treatment groups receiving varying doses of the extract (100 mg/kgBW, 300 mg/kgBW, and 500 mg/kgBW). Caspase-3 expression in the spleen was measured after 24 hours of treatment. The results demonstrated a significant reduction in Caspase-3 expression, particularly in the group treated with 500 mg/kgBW of the extract, indicating its anti-apoptotic effect. These findings suggest that P. foetida leaf extract may serve as a potential therapeutic agent for reducing cell apoptosis in sepsis, warranting further investigation into its mechanisms and clinical pharmacological field.
ANALISIS KANDUNGAN FORMALIN DAN BORAKS PADA BUMBU GILING YANG DIJUAL DI PASAR AJIBARANG WETAN mildawati, ratna; Khumaini, Eko Hidayaturrohman; Prasetyawan, Fendy; Saristiana, Yuneka
PHARMACON Vol. 14 No. 3 (2025): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.14.2025.61687

Abstract

Ground spices are a key ingredient used as food additives in almost every dish, whether at home or in places that sell various types of food. The use of food additives (BTP) in food production processes needs to be closely monitored. Additives that are prohibited include formalin and borax. Formalin and borax are banned because they can cause damage to the brain, liver, and kidneys, and long-term use can result in death. This study aims to determine whether formalin and borax are present in ground spices sold at Ajibarang Wetan Market. The ground spice samples examined came from two vendors: Vendor A (garlic, galangal, ginger, candlenut, red chili, turmeric, mixed spices, and coriander) and Vendor B (shallots, garlic, turmeric, red chili, candlenut, and mixed spices). The ground spice samples sold by Vendor A and Vendor B tested negative for both formalin and borax. The method used involved color reaction tests. To detect formalin, a potassium permanganate (KMnO₄) color reaction was used, and to detect borax, turmeric paper was employed. The conclusion of this study is that the borax test results for both vendors (Vendor A and Vendor B) were negative, as there was no color change to orange or reddish-brown. The formalin test results for both vendors were also negative, as there was no change in color to clear.
Phytochemical Screening and Antibacterial Activity of Ethyl Acetate, n-Hexane, and Aqueous Fractions of White Teak (Tectona grandis Linn. f.) Leaves against Escherichia coli herman, herman; Setyawan, Ferdinta Daniasta; Dhafin, Anis Akhwan; Prasetyawan, Fendy
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.628

Abstract

This study aims to conduct a phytochemical screening and evaluate the antibacterial activity of ethyl acetate, n-hexane, and aqueous fractions of white teak (Tectona grandis Linn f.) leaves against Escherichia coli bacteria. Phytochemical screening was performed to identify active compounds with potential antibacterial properties, such as flavonoids, tannins, saponins, alkaloids, and terpenoids. The antibacterial activity was tested using the disk diffusion and broth dilution methods to determine the inhibition zone, Minimum Inhibitory Concentration (MIC), and Minimum Bactericidal Concentration (MBC). The diffusion test results showed that ethanol extract (11.3 ± 1.02 mm) and the ethyl acetate fraction (18.1 ± 2.46 mm) exhibited significant antibacterial activity, whereas the n-hexane and aqueous fractions did not show any inhibition zones. Statistical analysis using ANOVA indicated a significant difference in antibacterial activity among the treatment groups (F = 163.29; p < 0.05). The broth dilution test revealed that the ethyl acetate fraction had an MIC at a concentration of 12.5%, with an MBC at 25%.
Analisis Histopatologi Efek Antiinflamasi Ekstrak Etanol Daun Akar Sebiak (Gynura procumbens (Lour.) Merr.): Histopathological Analysis of the Anti-inflammatory Effect of Ethanol Extract of Akar Sebiak Leaves (Gynura procumbens (Lour.) Merr. Saristiana, Yuneka; Prasetyawan, Fendy; Savitri, Lisa
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 7 No. 1 (2025): Volume 7 No 1 2025
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v7i1.6670

Abstract

Penelitian ini bertujuan mengevaluasi efek antiinflamasi ekstrak etanol daun Akar Sebiak (Gynura procumbens (Lour.) Merr.) melalui analisis histopatologi pada tikus putih jantan yang diinduksi Complete Freund’s Adjuvant (CFA). Hewan uji dibagi menjadi lima kelompok: kontrol normal, kontrol positif (Triamsinolon Asetonid), kontrol negatif (CMC-Na 1%), dan ekstrak dosis 100 mg/kg BB serta 200 mg/kg BB. Parameter yang diamati meliputi penurunan volume udem, jumlah leukosit total, dan lebar joint space. Hasil menunjukkan ekstrak dosis 100 mg/kg BB dan 200 mg/kg BB menurunkan volume udem masing-masing sebesar 43,33% dan 49,15%, menurunkan jumlah leukosit, serta memperbaiki joint space dibandingkan kontrol negatif. Efek antiinflamasi ini diduga terkait kandungan flavonoid, alkaloid, dan triterpenoid/steroid yang menghambat jalur inflamasi. Meskipun potensi ekstrak signifikan, efeknya masih di bawah triamsinolon asetoniid.
Identification of Transcribing Errors in Prescriptions for Type 2 Diabetes Mellitus Patients at Clinic X, Jember Haris Agung; Shinta Mayasari; Fendy Prasetyawan
Indonesian Pharmacopeia Journal Vol. 2 No. 1 (2025): January 2025
Publisher : LPPM Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/ipj.v2i1.39

Abstract

Abstract Background: Clinical Pharmacy Services play an important role in health services in hospitals. Pharmaceutical service standards are direct and responsible services to patients related to pharmaceutical preparations with the aim of achieving definite results to improve the quality of life of patients. Medication error (ME) is an incident that causes or has an impact on inappropriate drug services or endangers patients when the drug is under the control of health workers or patients. Transcribing Error (TE) is an error in reading a prescription before entering the dispensing stage. TE includes changes to the drug name, drug formulation, route, dose, dosage regimen to prescription orders. According to the East Java Health Service in 2021, Diabetes Mellitus (DM) sufferers in East Java were 2.6 of the population aged 15 years and over. Health services for diabetes mellitus sufferers at first-level health facilities (FKTP) in 38 districts/cities throughout East Java reached 867,257 cases (93.3% of the estimated DM sufferers. Based on dataBasic Health Research, 2021cases of diabetes mellitus in Jember amounted to 1.4%. This study aims toIdentifying transcription errors in prescriptions for type 2 DM patients at clinic x, Jember district. This research uses research descriptive using observation method The data source taken from this study is data from outpatient prescriptions for type 2 Diabetes Mellitus for the period January - December 2022-2024 at clinic x Jember district. The population of this study was 37 medical prescriptions for outpatients with type 2 DM for the period January - December 2022-2024 at clinic x Jember. The sample in this study was prescription data for patients diagnosed with type 2 DM who met the inclusion and exclusion criteria with a total of 37 samples by total sampling. The results of this study were obtained. Data from the identification of transcription errors still contained errors. From the total sample taken, 37 prescriptions, the results of the identification of transcription errors still contained errors including no medical record number (89.2%) no patient age (45.9%) no dosage form (43.2%). While the parameters of patient name, drug name, dosage, duration of administration, route of administration, date of prescription request have been complete, there are no errors.From the discussion above, it can be concluded that the results of transcription error identification still contain errors. Keywords:Medication error, transcribing error, DM type 2
Pengenalan Metode Imunodiagnostik Dasar untuk Pencegahan Penyakit Menular di Peternakan Savitri, Lisa; Kasimo, Elfred Rinaldo; Krissanjaya, Rochmad; Prasetyawan, Fendy; Saristiana, Yuneka; Amanda, Cornelia; Mebung, Konradus Klala
Abdimas Galuh Vol 8, No 1 (2026): Maret 2026
Publisher : Universitas Galuh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25157/ag.v8i1.23354

Abstract

Penyakit menular pada ternak masih menjadi salah satu kendala utama dalam usaha peternakan rakyat karena dapat menurunkan produktivitas dan menyebabkan kerugian ekonomi. Salah satu upaya pencegahan yang dapat dilakukan adalah deteksi dini penyakit melalui metode imunodiagnostik dasar. Namun, tingkat pemahaman peternak mengenai prinsip kerja dan pemanfaatan metode imunodiagnostik masih relatif rendah. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan pemahaman peternak mengenai pengenalan penyakit menular serta prinsip dasar metode imunodiagnostik sebagai langkah awal pencegahan penyakit di peternakan. Kegiatan dilaksanakan melalui penyuluhan interaktif, diskusi dua arah, serta demonstrasi penggunaan alat imunodiagnostik dasar berupa kit uji cepat. Sasaran kegiatan adalah peternak ternak rakyat di wilayah sasaran pengabdian. Evaluasi dilakukan melalui pengukuran tingkat pengetahuan peserta sebelum dan sesudah kegiatan serta observasi partisipasi aktif selama kegiatan berlangsung. Hasil kegiatan menunjukkan adanya peningkatan pemahaman peternak terkait jenis penyakit menular, prinsip reaksi antigen–antibodi, dan manfaat penggunaan metode imunodiagnostik dalam deteksi dini penyakit. Selain itu, peternak menunjukkan antusiasme dan partisipasi aktif selama proses penyuluhan dan demonstrasi. Kegiatan ini memberikan kontribusi positif dalam meningkatkan kesadaran peternak terhadap pentingnya pencegahan penyakit menular melalui pendekatan diagnostik sederhana yang aplikatif di tingkat peternakan rakyat.
Co-Authors Abd Rofiq Achmad Wahdi Adiyansyah Lukman Hakim Akhmal Muslikh, Faisal Akhmal, Faisal Alshol, Mohammad Firdaus Althaf Rajahala B Sinun Alves, Silvina Sandra X. Amanda, Cornelia Ana Amalia Anak Agung Indah Krisnadewi Anis Akhwan Dhafin Anis Akhwan Dhafin Anis Akwan Dhafin Anita Dwi Setyarini Apriliyani, Fitria Ardianto, Nanda Arifani Siswidiasari arikha ayu susilowati Arista Wahyu Ningsih Arsiaty Sumule Ary Kristijono Asrizal Azis Astutik, Widhi Ayu Angger Putri M. Soleh Azis, Asrizal Baarik Lana Fadli Bandhi Prasetya Nugroho Besan, Ema Jayanti Besan, Emma Jayanti Candra Arifin, Candra Chadra Arifin Chandra Arifin Charliandri Saputra Wahab Dafin, Anis Akhwan Dahbul, Nura Ali Dameria, Gempita Hutami Datin An Nisa Sukmawati Deo Rudita Febrian Waly Dewi Retno Puspitosari Dian Permatasari, Yunita Dyah Aryantini, Dyah Edda, Ilda Rambu Eka Hayati Rhomah Eka Nur Fatmawati Elfred Rinaldo Kasimo, Elfred Rinaldo Elsa Mahardika Dhafin Elsa Mahardika Putri Elsa Mahardika Putri Elsa Mahardika Putri Ema Tri Wulan Emma Jayanti Besan Erawati, Dyah Anisa Indri Evi Kurniawati, Evi Evi Nurul Hidayati Faisal Akhmal Muslihk Faisal Akhmal Muslikh Faisal Akhmal Muslikh Faisal Akhmal Muslikh Febriana, Laela Fita Sari Fita Sari, Fita Fitrani Khansa Fitriani, Evi Tunjung Freitas, Maria Do Carmo Da Costa Gunawan Pamudji Widodo Hakim, Adiyansyah Lukman Hamzah, Hasyrul Haris Agung Hasriyani Hasriyani Hasriyani, Hasriyani Herman Hilmi, Mochammad Hanif Ibrahim Fadlannul Haq Ibrahim Irsyadul Ibad Ibrahim Iskandar Alfaris Ika Purwidyaningrum Ilhawa Zahra Imran, Arlan K Indrayanti, Dian Iramadona, Putri Ayu Isma Oktadiana Ivan Junius Mesak Juan Vega Mahardhika Juwita, Syntia Tanu Kadir, Mujtahid Bin Abd Kadir, Mujtahid Bin And Karingga, Devangga Darma Kholis, Muhammad Akbar Nur Khumaeni, Eko Hidayaturrohman Khumaini, Eko Hidayaturrohman Koernia, Lilik Wahidah Kristjono, Ary Laili, Nur Fahma Leny Witaning Kusumati Lily Aina Lusiana Aprillia M. Wahyu Ariawan M. Yogi Riyantama Isjoni Ma'arif, Burhan Maharani Dwi Pratiwi Marhenta, Yogi Bhakti maswan daulay Ma’arif, Burhan Mebung, Konradus Klala Megasari, Elly Meri, Meri milda, ratna Mildawati, Ratna Mildwati, Ratna Muhammad Alviyan Shutiawan Muhammad Alviyan Shutiawan Muhammad Nurul Fadel Mujtahid Bin Abd Kadir Muslihk, Faisal Akhmal Muslikh, Faisal Nanda Ardianto Nanda Ardianto Neni Probosiwi Nimas Ayu Rahardini Nina Nur Jannah Nisa Azzahra Dentika Novyananda Salmasfattah Novyananda Salmasfattah Nur Fahma Laili Octavian Ashido Nababan Okky Intan Mawarni Okky Intan Mawarni okta, isma Oktadiana, Isma Permata, Agung Prasetyo Nugroho, Bandhi Prayoga Fery Yuniarto Prayogi, Syaiful Purnomo Puspitosari, Dewi Retno Putri, Elsa Mahardika Raharjo, Susilo Margining Ratna Mildawati Ratno Setyobudi Restyana, Anggi Rhomah, Eka Hayati Rika Wahyu Pujiastini Rochmad Krissanjaya Rofiq, Abd Rohmah, Eka Hayati Rosa Juwita Hesturini Sado, Yosep Mansen Salim Efendy Salmasfattah, Novyananda Salmasfattah, Novynanda savitri, Lisa Setyawan, Ferdinta Daniasta Shinta Mayasari Shinta Mayasari Shutiawan, Muhammad Alviyan Siti Nur Maulita Sugeng Rianto Sugeng Santoso Susilo Margining Raharjo Syntia Tanu Juwita Tri Wulan, Ema Tsamrotul Ilmi Wahab, Charliandari Saputra Widhi Astutik Widiyastuti, Asih Winartiana Winartiana, Winartiana Wisnu Haryo Widyoko Wulan, Ema Tri Yanti, Novirma Yogi Bhakti Marhenta Yosep Mosse Yuneka Sarisitiana Yuneka Saristiana Yuniarto, Prayoga Feri Yunita Dian Permatasari Zahra, Ilhawa Zenmas, Syendriva Zeptyan