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All Journal International Journal of Electrical and Computer Engineering Torani Journal of Fisheries and Marine Science Lintas Ruang: Jurnal Pengetahuan dan Perancangan Desain Interior Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Ilmiah Mahasiswa FEB Journal of Biomedicine and Translational Research Jurnal Ilmu Kelautan Spermonde JURNAL IPTEKS PEMANFAATAN SUMBERDAYA PERIKANAN Biomedical Journal of Indonesia Sinkron : Jurnal dan Penelitian Teknik Informatika Medical Laboratory Technology Journal Pendas mahakam : jurnal pendidikan dan pembelajaran Sekolah Dasar JURNAL MUQODDIMAH : Jurnal Ilmu Sosial, Politik dan Hummaniora Jurnal Ilmiah Mahasiswa Kedokteran Medisia Jurnal Pendidikan Matematika (JUDIKA EDUCATION) Fair Value: Jurnal Ilmiah Akuntansi dan Keuangan Jurnal Teknologi Sistem Informasi dan Aplikasi JURNAL PENDIDIKAN TAMBUSAI SRIWIJAYA JOURNAL OF MEDICINE ACTIVE: Journal of Physical Education, Sport, Health and Recreation Jurnal Teknologi Terpadu Jurnal Logistik Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Menssana Jurnal Mantik Riyadhoh : Jurnal Pendidikan Olahraga Imajeri: Jurnal Pendidikan Bahasa dan Sastra Indonesia Scientia Psychiatrica Journal of SPORT (Sport, Physical Education, Organization, Recreation, and Training) REMIK : Riset dan E-Jurnal Manajemen Informatika Komputer Jurnal PORKES RESLAJ: RELIGION EDUCATION SOCIAL LAA ROIBA JOURNAL Sriwijaya Journal of Surgery Open Access Indonesia Journal of Social Sciences Sriwijaya Journal of Ophthalmology JURNAL PENDIDIKAN SAINS SOSIAL DAN AGAMA Eureka Herba Indonesia Jurnal Kesehatan Tambusai Jurnal Pengabdian Masyarakat: Humanity and Medicine PRAJA observer: Jurnal Penelitian Administrasi Publik Natural Sciences Engineering and Technology Journal Oikonomia: Jurnal Manajemen Open Access Indonesian Journal of Medical Reviews Indonesian Community Empowerment Journal Jurnal Abdimas Bina Bangsa Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Open Access Indonesia Journal of Social Sciences Arkus Abditeknika - Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Kepada Masyarakat Patikala International Journal of Research and Applied Technology (INJURATECH) Muhasabatuna: Jurnal Akuntansi Syariah Journal of Informatics and Communication Technology (JICT) Journal of Anesthesiology and Clinical Research Journal Of Human And Education (JAHE) Scriptura : Jurnal Ilmiah Sustainability Science and Resources Journal International of Lingua and Technology Proceeding ISETH (International Summit on Science, Technology, and Humanity) Indonesian Journal Computer Science (ijcs) Journal Health Information Management Indonesian Indonesian Research Journal on Education Dikdimas : Jurnal Pengabdian Kepada Masyarakat Jurnal Muara Olahraga Jurnal Multidisiplin Sahombu Jurnal Pengabdian West Science Sinergi International Journal of Communication Sciences Jurnal Sosial, Sains, Terapan dan Riset (Sosateris) Technology and Society Perspectives (TACIT) Scientific Journal of Pediatrics Jurnal Spektrum Komunikasi Sriwijaya Journal of Radiology and Imaging Research Journal of Social Science Utilizing Technology Sriwijaya Journal of Internal Medicine Sriwijaya Journal of Obstetrics and Gynecology Sriwijaya Journal of Otorhinolaryngology Jurnal Pengabdian Sosial Informatics and Software Engineering (ISE) Jurnal Perikanan Terpadu Journal of Informatics and Communication Technology (JICT) Journal of Social Science Utilizing Technology Journal of Industrial Engineering Innovation Acta Psychologia ACTIVE: Journal of Physical Education, Sport, Health and Recreation Communica : Journal of Communication Bambu Laut: Jurnal Pengabdian Masyarakat
RACHMAT HIDAYAT
Department Of Medical Biology, Faculty Of Medicine, Universitas Sriwijaya, Palembang, Indonesia
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Journal : Biomedical Journal of Indonesia

 1   2 
MRNA NFATC1 EXPRESSION IN GENU OSTEOARTHRITIS WITH EFFUSION Reagan, Muhammad; Hermansyah, Hermansyah; Hidayat, Rachmat; Darma, Surya; Muthia, Putri
Biomedical Journal of Indonesia Vol 6, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v6i2.10418

Abstract

Based on a study conducted by the WHO Global Burden of Disease in 2010 stated, OA ranks 11th, the cause of disability in the world, and ranks 6th in East Asia and the Asia-Pacific countries, ranked 10th in North America, ranked 7th in Eastern Europe , and ranked 13th in Western Europe. Pathogenesis of osteoarthritis (OA) as degenerative joint disease that was once thought caused by a mechanical process. The prevalence, etiology, pathogenesis and progression of OA are still not understood until now, mainly because of the many influencing factors. This type of research is a analytic study. It was conducted in Rheumatology Polyclinic Dr. Mohammad Hoesin Palembang from February to December 2019. Affordable research population is all genu osteoarthritis sufferers with effusion who go to Dr. RSUP Mohammad Hoesin Palembang as 80 samples. Comparison of NFATC1 mRNA levels in genu osteoarthritis patients with effusion shows that there is no difference in gender and history of diabetes, whereas hypertension history and degree of osteoarthritis based on Lawrence Kalgren shows significantly different expression of NFATC1 mRNA. Age with NFATC1 mRNA expression showed no significant correlation, in contrast to BMI, Stroke Test and joint effusion volume showed a weak significant correlation, even though the direction of the correlation was negative on Stroke Test and joint effusion volume.
MRNA NFATC1 EXPRESSION IN GENU OSTEOARTHRITIS WITH EFFUSION Reagan, Muhammad; Hermansyah, Hermansyah; Hidayat, Rachmat; Darma, Surya; Muthia, Putri
Biomedical Journal of Indonesia Vol 6, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v6i2.10418

Abstract

Based on a study conducted by the WHO Global Burden of Disease in 2010 stated, OA ranks 11th, the cause of disability in the world, and ranks 6th in East Asia and the Asia-Pacific countries, ranked 10th in North America, ranked 7th in Eastern Europe , and ranked 13th in Western Europe. Pathogenesis of osteoarthritis (OA) as degenerative joint disease that was once thought caused by a mechanical process. The prevalence, etiology, pathogenesis and progression of OA are still not understood until now, mainly because of the many influencing factors. This type of research is a analytic study. It was conducted in Rheumatology Polyclinic Dr. Mohammad Hoesin Palembang from February to December 2019. Affordable research population is all genu osteoarthritis sufferers with effusion who go to Dr. RSUP Mohammad Hoesin Palembang as 80 samples. Comparison of NFATC1 mRNA levels in genu osteoarthritis patients with effusion shows that there is no difference in gender and history of diabetes, whereas hypertension history and degree of osteoarthritis based on Lawrence Kalgren shows significantly different expression of NFATC1 mRNA. Age with NFATC1 mRNA expression showed no significant correlation, in contrast to BMI, Stroke Test and joint effusion volume showed a weak significant correlation, even though the direction of the correlation was negative on Stroke Test and joint effusion volume.
Regulation of Cell Cycle Rachmat Hidayat; Hayati, Lusia
Biomedical Journal of Indonesia Vol. 6 No. 3 (2020): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v6i3.236

Abstract

The cell cycle is a vital process in the life of every organism. Normally, the cell cycleresults in cell division. Cell division consists of 2 main processes, namely DNAreplication and chromosome division that has been duplicated into 2 daughter cells.Cyclin is expressed periodically so that the cyclin concentration varies at each phase ofthe cell cycle. Cdks are threonine or serine protein kinases which must bind to cyclinfor its activation. The concentration of Cdks is relatively constant during the cell cycle.Cyclin-dependent kinase inhibitor (CKI) is a protein that can inhibit Cdk activity bybinding to Cdk or the cyclin-Cdk complex
Molahidatidosa from Pathophysiology to Clinical: Literature Review Hidayat, Rachmat; Irawan Sastradinata
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.260

Abstract

A B S T R A C THydatidiform is a gestational trophoblast disease which is histopathologicallycharacterized by the proliferation of avascular trophoblast cells and corial villi andundergoing hydrophic degeneration. The proliferation of trophoblast cells inhydatidiform moles can be in the form of cytotrophoblast, syncytiotrophoblast orintermediate trophoblast proliferation.
Sarcopenia from Pathophysiology to Clinical : Literature Review Hidayat, Rachmat; Nur Riviati
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.261

Abstract

A B S T R A C TThe causes of sarcopenia are thought to be multifactorial including: environmentalfactors, illness, activation of inflammatory pathways, mitochondrial dysfunction, lossof neuromuscular junctions, reduced number of satellite cells and changes in thequality of hormonal function. The mechanism of sarcopenia occurs because the agingprocess coupled with reduced physical activity can cause the formation of cytokinesto increase so that inflammation is easy, insulin resistant, anabolic resistance andneuromuscular impairments.
Omega-3 as an Anti-Inflammatory Modality: Literature Review Hidayat, Rachmat; Nur Riviati
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.262

Abstract

A B S T R A C TOmega-3 fatty acids are polyunsaturated fatty acids that have multiple double bonds,the first double bond is located on the third carbon atom of the omega-methyl group,the next double bond is located at the third carbon atom from the previous doublebond. The methyl omega group is the last group in the fatty acid chain. Omega-3 fattyacids are nutrients that play a vital role in the growth and development process ofbrain neuron cells for the intelligence of the born baby.
Bioethical Principles of Use of Experimental Animals in Biomedical Research Hidayat, Rachmat; Patricia Wulandari
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.267

Abstract

A B S T R A C TResearch is an activity carried out based on scientific principles and methodssystematically to obtain information, data, and information from related subjects, withunderstanding the theory and proving assumptions and / or hypotheses. The resultsobtained are conclusions that can be applied or become additional knowledge for theadvancement of science. However, research activities must still respect the rights anddignity of research subjects. Health research includes biomedical, epidemiological,social, and behavioral research. Some health research can be done in vitro, usingmathematical models, or computer simulations.
Anatomy and Physiology of Animal Model Rats in Biomedical Research Hidayat, Rachmat; Patricia Wulandari
Biomedical Journal of Indonesia Vol. 7 No. 2 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i2.287

Abstract

A distinguishing feature of rodents, including rats, is the absence of canines and thepresence of prominent incisors. Rats are monophydontic, meaning they grow one setof teeth in their lifetime. The enamel of the rodent incisor contains iron, which givesit its yellow-orange color. Rats are mammals and as such, possess many similaritieswith other mammals. Only the peculiarities of the rat’s anatomy are addressed. Malerats reach puberty at 40 - 60 days of age. Descent of the testes usually occursbetween days 30 - 60. Sperm counts vary by strain. The male rat has an os penis.Male rats have the following accessory sexual organs: ampulla, seminal vesicles,prostate, bulbourethral glands, coagulating glands, and preputial glands. Thecoagulating gland and prostatic and vesicular secretions are responsible for thecopulation plug, a firm plug deposited in the vagina of the female after copulation.(This plug, when found outside the female rat, is capsuleshaped and approximately5 mm long.) The male rat has no nipples. The adult male rat has a prominentscrotum and a longer anogenital distance than the female rat.
mRNA NFATC1 Expression in Genu Osteoarthritis with Effusion Muhammad Reagan; Hermansyah; Rachmat Hidayat; Surya Darma; Putri Muthia
Biomedical Journal of Indonesia Vol. 6 No. 2 (2020): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Based on a study conducted by the WHO Global Burden of Disease in 2010 stated, OA ranks11th, the cause of disability in the world, and ranks 6th in East Asia and the Asia-Pacificcountries, ranked 10th in North America, ranked 7th in Eastern Europe , and ranked 13th inWestern Europe. Pathogenesis of osteoarthritis (OA) as degenerative joint disease that was oncethought caused by a mechanical process. The prevalence, etiology, pathogenesis and progressionof OA are still not understood until now, mainly because of the many influencing factors. Thistype of research is a analytic study. It was conducted in Rheumatology Polyclinic Dr.Mohammad Hoesin Palembang from February to December 2019. Affordable researchpopulation is all genu osteoarthritis sufferers with effusion who go to Dr. RSUP MohammadHoesin Palembang as 80 samples. Comparison of NFATC1 mRNA levels in genu osteoarthritispatients with effusion shows that there is no difference in gender and history of diabetes, whereashypertension history and degree of osteoarthritis based on Lawrence Kalgren shows significantlydifferent expression of NFATC1 mRNA. Age with NFATC1 mRNA expression showed nosignificant correlation, in contrast to BMI, Stroke Test and joint effusion volume showed a weaksignificant correlation, even though the direction of the correlation was negative on Stroke Testand joint effusion volume.
Regulation of Cell Cycle Rachmat Hidayat; Lusia Hayati
Biomedical Journal of Indonesia Vol. 6 No. 3 (2020): Vol 6, No 3, 2020
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v6i3.236

Abstract

The cell cycle is a vital process in the life of every organism. Normally, the cell cycle results in cell division. Cell division consists of 2 main processes, namely DNA replication and chromosome division that has been duplicated into 2 daughter cells. Cyclin is expressed periodically so that the cyclin concentration varies at each phase of the cell cycle. Cdks are threonine or serine protein kinases which must bind to cyclin for its activation. The concentration of Cdks is relatively constant during the cell cycle. Cyclin-dependent kinase inhibitor (CKI) is a protein that can inhibit Cdk activity by binding to Cdk or the cyclin-Cdk complex
Co-Authors Abdul Mahatir Najar Abdulwahab Hakimi Abu Bakar Abu Bakar Abudarda, Andi Risda Fitrianti Achmar Mallawa Adnindya, Msy Rulan Agus Indra Jaya Agus Junaidi Agus Junaidi Agustian, Kresnawidiansyah Ahadi Aulia Rahman Ahmad Ahmad Ahmad Fatoni Ahmad Salim, Ahmad ahmad yani Ahmad Zain Sarnoto Ahmad, Arfandi Aji, Muhammad Pramono Alhan, Khusni Alif Tunru, Andi Alvian, M. Andri Anang Tribowo Andayani, Nurfitri Andiani, Lia Andres Andres Andriana, Nadila Andronias Siregar Annisa Wimaulia Azlin Anuar, Arman Bin Aprilyanti, Cindy Apriwandi . Arifin, Nurdin Arindi Maretzka Aryanto, Hermawan Noval Ayeshah A Rosdah Azakhia, Yolanda Citra Baharuddin Baharuddin Bainamus, Putri Milanda Bella Stevanny Bemba, Tonia Buchari Buchari Budi Pratiti Carla R Marchira Catherine Christine, Debbie Cinthya Callathea Dahlan, Dadang - Dariyanto, Erwin Debby Handayanti Harahap Dessa, Rima Djoko Widodo Edith Humries edy susanto Ella Amalia, Ella Ellya Verawati Elsa Iskandar Erizka Rivani Erma Agusliani Ester G Pansserga Fahcreza Faisal Syahputra, Faisal Fajarwati, Lia Fathonah, Andina Nur Fatmawati Fatmawati Fatmawati Fildzah Hashifah Taufiq Fiona Widyasari Firjatullah, Andhika Fauziana Griselda Griselda Hadi, Dudi Abdul hadi, marwan Handayani, Lisa Hani Subakti Haryanto Haryanto Herman Paninggiran Hermansyah Hermansyah Hermansyah Herry Hasnawi HUSNUL KHOTIMAH Ichsan, Amirul Ika Kartika Ikrima Ikrima Ilahi, Rahmat Imam Pribadi Inggarsih, Rara Irawan Sastradinata Irawan Sastradinata Irham Irham Irsan Saleh Ismar Hamid Iwan Setiawan Jamalullail Jayawarsa, A.A. Ketut Joko Marwoto Joko Marwoto Junoretta Haviva Ernanto Kashardi, Kashardi Kemas Abdul Mutholib Luthfi Kemas Ya'kub Rahadiyanto Krishna, Hidan Bayu Krisna Murti Kumba Digdowiseiso, Kumba KURNIA KURNIA, KURNIA Lestari Barus, Irene Sukma Linda Purnama Listianingsih, Lona Lusia Hayati Lusia Hayati Lusia Hayati Lusia Hayati Lusia Hayati, Lusia Luthfi, Kemas Abdul Mutholib Mail, Abdul Maisya, Irin Makbruri Amin Malik, Aulia Januar Maria Margareth Wilson Marlinda, Dwi Martino Dwi Nugroho MARYANTI, LILIS Maslukin, Maslukin Mauladan, Ravy Maximillian Wilson Meilinda, Salsa Rizkia Mgs Irsan Saleh Mgs Irsan Saleh Mirna Dianita Muallin, Muallin Mubarok, E. Saefuddin Muhammad Anzarach Pratama Muhammad Bima Muhammad Irsan Saleh Muhammad Reagan Muhammad Reagen Muhammad Ridwan Muhammad Rizky Hidayatullah Muhlis Muhlis Mukti Zainuddin Murlena, Murlena Muslina Muslina Muthia, Putri Muthia, Putri Nadia Khoirina Najla Khairunnisa Nandang Iriadi Nani Solihati Nasriandi Nasriandi Ninuk Riesmiyantiningtias Nita Parisa Noorzaman, Sandi Noviyan, Rizky Dwi Nur Ainun Nur Riviati, Nur Nur, Suaib Nurdina, Mutia Nurhasanah Nurhayati, M Sinta nurliah, nurliah Nurpahni, Siti Salma Nurrahmah, Andi Oktaviyani, Hikmatul Olivia Azalia Putri Pamungkas, K J paosan, ahmad Patricia Wulandari Patry, Him Petty Purwanita Poku, Ham pongtiku, ita Prakarsa, Bambang Pramono, Yacob Agung Prayudhi, Risa Prihatina Anjela Purnamasari, Septi Puspa Sari, Puspa Puspa Zulaika Puspita, Sabrina Diah Puspitasari, Andini Putra, Suadi Sapta Putri Muthia Rachman, Andry Arifian Raden Ayu Adelia Safitri Raden Sunita Radiyati Umi Partan Radjikan Rahayu, Rosi Rahman, Ahadi Aulia Rahman, Ahadi Aulia Rahman, Alfi Rahmat Saleh Raihan Aqiilah N.L. , Andi Ahmad Ramadana, Radiyah Ramadhan, Hamzah Ramadhani, Anjas Ramli, Musdalifah Rara Inggarsih Rara Inggarsih Rashidah Unaib Al Zayid Rasyidah Jalil Reisha Notonegoro Resva Meinisasti Rety, Alghazali Riani Erna Rijaluddin, Khalid Rima Rachmawati Riri Juliantika Risnanosanti Risnanosanti Riswanto, A Heri Riswanto, A. Heri Riswanto, Andi Heri Riswanto, Heri Rosiyadi, Didi Safi'i, Imam Safruddin Sahidan Sahidan Sahidan Sahidan Sahni Putri, Andi Rani Saksitha, Deassy Arestya Salni Salni Saman, Saman Samsuri, Fhadil Hidayat Sapinah, Pipin Sarah Sari , Windy Dian Sari H. S., Maharani Puspita Sari, Anggi Psutpita Sari, Windy Dian Sarmila, Sarmila Sarnato, Ahmad Zain Satriansyah , Arief Sekarini, Ratih Ayu Sepang, Rosa Marten Septi Purnamasari Septi Purnamasari SEPTIAN, DIAN Shalita Dastamuar Shina Abdulkadir Sony Sanjaya Sonya Syarifah Sri Nita Sri Nita Sri Nita Sri Nita, Sri Sri Tuti Rahmawati Sri Vandayuli Riorini St. Aisjah Farhum, St. Aisjah Sudaramanto, Bagus Sujud, Atsari Surya Ade Saputera Surya Darma Surya Darma Syarif Burhan, Ahmad Tanjung, Enha Syahrul Taufiq Indera Jayadi Tiara Fatrin Triwani Triwani Triwani Tungki Pratama Umar Tungki Pratama Umar Tunru, Andi Alif Udi Rusadi Uswatun Hasanah Veithzal Rivai Zainal Wahyudin Wahyudin Wardani, M. Fikri Wardiansyah Wiganepdo, Suryatno Wijaya, Maya Septa Winda Ramadianti, Winda Wirna, Risalah Sabila Yeni Agustin Yuliansyah, Chandra Yundari, Yundari Yuni sahruni, Ade Yusnaini Yusnia Budiarti Zaidan, Naufal Muhamad Zakaria, Khairunnisa Zen, Agustian Ziske Maritska