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Journal : Majority

Hubungan Frekuensi Harian Mencuci Wajah dan Pemakaian Sabun Wajah Anti Akne Dengan Derajat Keparahan Akne Vulgaris pada Remaja Putri di SMAN 10 Bandar Lampung Annisa Adietya Pratama; Dwi Indria Anggraini; Syazili Mustofa
MAJORITY Vol 10 No 1 (2021): MAJORITY
Publisher : Majority

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Abstract

Acne vulgaris is a skin problem that often occurs in teenager. Some factors that can cause acne vulgaris include genetic, hormonal, infection, trauma, and diet. The degree of acne is divided into mild, moderate, and severe degrees. Washing face is a prevention or treatment of acne vulgaris, it should be noted the use of the type of face wash and the frequency of facial washing with the incidence of acne vulgaris. Purpose of this research is to find out the relationship of daily frequency facial washing and use of anti acne face wash to the severity of acne vulgaris in teenage girl at SMAN 10 Bandar Lampung. This research used analytic observational method with cross sectional approach. The sample of the research is 89 respondents and using purposive sampling method. The result of univariate analysis was 56,2% of respondents use anti acne face wash and 57,3% of respondents wash their faces ≥ 3 times a day. The result of bivariate analysis showed some variables had a correlation with with the severity of acne vulgaris is the use of anti acne face wash (p value 0,016). Meanwhile, some variables had no correlation with the severity of acne vulgaris witch is the frequency of daily facial washing (p value 0,582). The conclusion is there was relationship between the use of anti acne face wash and the severity of acne vulgaris and there was no relationship between daily frequency facial washing with the severity of acne vulgaris
Diagnosis dan Penatalaksanaan Penyakit Arteri Perifer Christi Natalia Sirait; Syazili Mustofa
MAJORITY Vol 10 No 1 (2021): MAJORITY
Publisher : Majority

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Abstract

Peripheral artery disease (PAD) is one of the most prevalent conditions, and it frequently coexists with vascular disease in other parts of the body. Early diagnosis is important for improving the patient’s quality of life and for reducing the risk of serious secondary vascular events such as acute myocardial infraction (AMI) or stroke. The best noninvasive measure for identifying the presence of occlusive arterial disease is the ankle-brachial index. Lower extremity PAD most frequently presents with pain during ambulation, which is known as “intermittent claudication”. Some relief of symptoms is possible with exercise, pharmacotherapy, and cessation of smoking. The occurrence of PAD is caused by insufficiency in the arteries due to the occurrence of the atherosclerosis process. Aspirin inhibits platelet synthesis through irreversible acetylation of cyclooxygenase (COX) enzymes on platelets. Because platelets do not have a nucleus, platelets are not able to form (COX) enzymes during their lifetime. As a result, the synthesis of thromboxane A2 (TXA2) which plays a major role in platelet aggregation is inhibited. Thus, long-term aspirin in the long term can prevent myocardial infarction and PAD.
Penggunaan Klinis Aktivitas Enzim Gamma-Glutamyl Transferase (GGT) Plasma dan Potensinya sebagai Biomarker untuk Berbagai Penyakit Benny Syahputra Gumay; Syazili Mustofa
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

Gamma-Glutamil Transferase (GGT) enzyme is a widely distributed transpeptidase in various body tissues. This enzyme is located in cell membranes and cytoplasm of hepatocytes. In addition, the expressions of the GGT enzyme is found in the kidneys, lungs, pancreas, blood vessel endothelium, nerve cells, and blood plasma. It has been used routinely in clinic to diagnose liver damage caused by alcoholism. The normal value of plasma GGT activity is 0–40 U / l. Normally, the GGT activity in blood plasma is low, but liver damage or bile ducts obstruction will increase it. There were significant association between the GGT activities in plasma and various diseases such as cardiovascular disease, metabolic syndrome such as diabetes mellitus and obesity, neurological and neurodegenerative diseases and others various diseases. Related to the measurement of GGT enzyme activity is cheap and easy to do, it's very potential to be developed for marker to diagnosis, prognosis, and further evaluation of various diseases. Further studies are needed to apply it for to be an accurate biomarker for various diseases
Hipertensi: Gambaran Umum Naufal Rivo Aditya; Syazili Mustofa
MAJORITY Vol 11 No 2 (2023): MAJORITY
Publisher : Majority

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Abstract

Chronic disease is a worldwide health issue. The prevalence of chronic disease is 6,7 billion people worldwide, and has increased over the time. Chronic disease is a noncommunicable disease, but chronic disease is a persistant disease and resulting in substansial years of life lost. One of the chronic diseases is hypertension or high blood pressure. The prevalence of hypertension is 1,2 billion people worldwide and increasing due to an aging population and increasing prevalence of obesity. Hypertension is multifactorial disease involving genetic factors and environmental factors. Aparts from these two factors, behaviors factors can be increasing risk factor for hypertension, such as smooking and excess salt consumption. AHA (American Heart Association) hypertension guidelines, hypertension is diagnosed when blood pressure is consistently >130 for systolic pressure, and or >80 mmHg for diastolic pressure. Hypertension have a significant effects due to CVD (Cardiovascular disease) such as hearth failure, myocardial infarction, stroke and death. Hypertension in older adults have a adverse effects and exacerbated by a decrease in body function and quality, such as mechanical hemodynamic changes, arterial stiffness, neurohormonal and declining renal function, so the management strategies for hypertension in older adults must consider from various aspects, such as comorbidities factors, pyscho-social factors. The management strategies for hypertension can be used non-pharmacological therapy to reduce the risk of hypertension severity and provide appropriate pharmacological therapy according to the patient’s condition, so that it can provide appropriate results.
Pengaruh Pemberian Ekstrak Biji Kopi Robusta (Coffea canephora) Lampung terhadap Aktivitas Enzim Katalase Hippocampus Tikus Putih (Rattus norvegicus) Jantan Galur Sprague dawley yang Diinduksi Monosodium Glutamat Syazili Mustofa; Ni Sayu Putu Desya Laksmi Putri; Lucky Togihon; Wayan Ferly Aryana; Rizki Putra Sanjaya; Tito Tri Saputra
MAJORITY Vol 12 No 1 (2023): MAJORITY
Publisher : Majority

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Abstract

Almost 60 million people worldwide have recovered from pulmonary tuberculosis since 2000, but many of them develop post-tuberculous lung disease. The disease results from a complex interaction between the disease-causing organism, the host, and environmental factors, and this affects the long-term airway. People with this disease have a shorter life expectancy and an increased risk of tuberculosis recurrence. Bronchiectasis is a disease of the dilation of the bronchial tubes which is characterized by decreased mucociliary transport function. It can also be caused by a bacterial infection with Post Tuberculosis Obstructive Syndrome (SOPT). SOPT is a lung disorder characterized by chronic airway obstruction due to complications arising from post-treatment pulmonary tuberculosis. This case describes a patient with bronchiectasis and SOPT who came with symptoms of shortness of breath accompanied by a long cough. From the results of the physical examination and supporting examinations, a working diagnosis was obtained in the form of infected brochiectasis accompanied by post-tuberculosis obstructive syndrome. The patient was then given therapy in the form of oxygenation, nebulized bronchodilators, corticosteroid injections, and antibiotics. In addition, patients are also given chest physiotherapy and a high-calorie, high-protein diet.
Co-Authors Achmad Gozali Ade Yonata Adityo Wibowo, Adityo Adli, Farhan Kamali Afriyana, Regi Agung Kurnia, Ahmad Fadila Agus Dwi Susanto Agus Wantoro Agustia Pratiwi agustyas tjiptaningrum Agustyas Tjiptaningrum Ahmad A Anindito Aisyah A Putri Ananta, Yoga andestya nanda pratama Andika Ridwan Nugraha Harahap Anggi Adelia Anggraeni Janar Wulan Anggraeni Janar Wulan, Anggraeni Janar Anggraeni, Liza Annisa Adietya Pratama Antoni Antoni Apga Repindo Ari Wahyuni Asep Sukohar Aviv Fitria Yulia Ayu, Putu Ristyaning Benny Syahputra Gumay Betta Kurniawan Betta Kurniawan, Betta Budhi Antariksa Caesaria Sinta Zuya Caesarridha, Dhaifany Karissa Chicy WIdya Morfi Christi Natalia Sirait Dansen Frans Louise Draven Rudyanto David Tongon Silaen Debby Handayati Harahap Dewi Nur Fiana Dheti Efrilia Dheti Efrilia - Dimas Trend PB Dorisman, Hari Dwi Indria Anggraini Dwi Sarwindah Dyah Wulan Sumekar Rengganis Wardani Ekawati, Diyan Eksa, Dwi Robbiardy Elman Dani Firdaus Endah Setyaningrum Ersa, Rakhmigasti Citra Erumbia, Ilham Akbar Ety Apriliana Evi Kurniawaty Evy Kurniawaty Faisal Rohmadhiyaul Haq Faisal Yunus Faisol Rohmadhiyaul Haq Fauziah Hanif Fayza Syachrani Febrianti, Arlin Febrihartati, Isura Feby Aulia Hasanah Femmy Andrifianie Fikri Muhammad Rifai Patongai Firantika Dias Puteri Fitria Saftarina Fitriyah . Fitriyah Fitriyah Fitriyah Fitriyah Fransisca Sinaga Fredison, Fredison Gerliandi, Egi Oktarian Gigih Setiawan Gilang Kukuh Megantoro Ginting, Bisart Giska Tri Putri Gusti Agung Putu Yogy Veda Ananta Gusti Wahyu, Pratiwi Hakim Alhaady Juhana Hakim Alhaady Juhana, Hakim Alhaady Hanna Mutiara, Hanna Helmi Ismunandar Hendri Busman Hendri Busman Herdato, M. Junus Didiek Hetti Rusmini I Made Afryan SL I Made Galih Fradiva Giantara Idzni Mardhiyah Ifan Aulia Candra Ilma Puteri Hutami Indri Windarti Infianto, Andreas Intan Kusumaningtyas Intanri Kurniati Isnamurti Ciptaningrum Isura Febrihartati Izzati, Marwah Aulia Jamsari Jamsari Jati, Pandu Kumaya Jhons Fatriyadi Suwandi Karima, Nisa Karina, Salwa Al Kevin Jeremia Purba Khairun Nisa Khoiri, Ratu Kirana Siva Kholis Abdurachim Audah Kurniawaty, Evi Kusumajati, Pusparini Linda Septiani Listiandoko, Raden Dicky Wirawan Lucky Togihon M. Rakha Gerizha M., Tria Mallarangeng, Andi Nafisah Tendri Adjeng Mayasari, Diana Meiwa Rizky Ardhi Blla Putri Mentariasih Maulida Mia Esta Poetri Afdal Faisal Mirza Purwitasari Morfi, Chicy Widya Muhammad Fitra Wardhana Sayoeti Muhammad Iqbal Muhammad Maulana Muhammad Ricky Ramadhian Muhartono Muhartono Muhartono NA, Ahmad Mufid Nadhifa, Farin Nadya Febriani Namdes, Fitri Cyntya Naufal Rivo Aditya Ni Sayu Putu Desya Laksmi Putri Nicholas Alfa Nickyta Yolandita Rosti Novita Carolia Novita Carolia Novita Carolia Nuriah Nuriah Nuriah, Nuriah Nursidiq, Iqbal Muhammad Rafi Oktadoni Saputra, Oktadoni Pinaka Baladika, Dimas Trend Poty, Pitha Maykania Pralia Winda Sari Pratama, Arianda Puan Raissa Lenka Puteri, Vadiyani Fricillya Putra, Andika Chandra Putranata, Naufal R. Putri Adilla Putri, Reny Arienta Rahmasari, Fania Asfi rahmawati, selvi Ramadhan, Muhammad Alif Ramadhana Komala Ramdini, Dwi Aulia Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi PS Ratna Dewi Puspita Sari Retno A S Soemarwoto Retno Ariza S Soemarwoto Retno Ariza S. Soemarwoto Retno Ariza Soeprihatini Soemarwoto Rheza Paleva Rika Lisiswanti Risal Wintoko Risti Graharti Rizki Putra Sanjaya Rizki Putra Sanjaya Rizki Putra Sanjaya Rosari HS, Felicya Rr Astri Nur Azizah Utama S Rahmanisa Sani, Nanda Apri Saputra, Tetra Arya Saputra, Tito Tri Sarasmita Nirmala Dewi Septiani, Linda Setiorini, Anggi Shina Megaputri Shinta Nareswari, Shinta Silaen, David Silvia Andriani Sinaga, Fransisca T.Y. Sinaga, Fransisca TY Siti Hazrina Soemarwoto, Retno Ariza Soemarwoto, Retno Ariza S Soemarwoto, Retno Ariza Soeprihatini Soeprihatini Soemarwoto, Retno Ariza Soeprihatini, Retno Ariza Soraya Rahmanisa Soraya Rahmanisa Soraya Rahmanisa Sri Janahtul Hayati Sri Janahtul Hayati Sri Puji Hartini Suharyani Suharyani Suharyani Suharyani Sukarti Sukarti Suryani Agustina Daulay Susianti Susianti Susianti Susianti Susianti, Susianti Sutarto Sutarto Sutyarso Sutyarso Sutyarso Suwarno, Sukarti San Syaka, Muthiiah Khodista Syakir, Muhammad Addin Syiefa Renanda Surya takhfa nur asyifa Tarigan, Clara Yulianti Terza Aflika Happy Tito Tri Saputra Tito Tri Saputra Tito Tri Saputra Tiwuk Susantiningsih Tri Umiana Soleha Tri Umiana Soleha Triyandi, Ramadhan Veny Anisya Victoria Hawarima Virginia, Nur Ayu W Bahagia Wawan Abdullah Setiawan Wayan Ferly Aryana Winda Trijayanthi Utama, Winda Trijayanthi Wisnugroho, Cahyo Wulan, Anggraini Janar Yana Ayu, Dwi Yandri Yanwirasti Yuningrum, Hesti Zen Hafy Zulia Yasminanindita Fahmi Zulkifli