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All Journal Nurse Media Journal of Nursing Medical Journal of Indonesia Indonesian Journal of Urology Gadjah Mada Journal of Psychology The Indonesian Journal of Public Health Majalah Obstetri dan Ginekologi Majalah Kedokteran Sriwijaya The Indonesian Biomedical Journal Sari Pediatri Universa Medicina Paediatrica Indonesiana Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Indonesian Journal of Cardiology Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Respirologi Indonesia Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Oto Rhino Laryngologica Indonesiana Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Journal Orthopaedi and Traumatology Surabaya (JOINTS) The New Ropanasuri Journal of Surgery ASEAN Journal of Community Engagement Indonesian Journal of Global Health research Jurnal Ilmu Bedah Indonesia Jurnal Sosial dan Teknologi Narra J Binawan Student Journal Indonesia Journal of Physical Medicine and Rehabilitation Cermin Dunia Kedokteran Indonesian Journal of Public Health Nutrition (IJPHN) The Indonesian Journal of Community and Occupational Medicine Indonesian Journal of Multidisciplinary Science Jurnal Locus Penelitian dan Pengabdian Indonesian Journal of Cancer Journal of Health and Nutrition Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal of General Procedural Dermatology and Venereology Indonesia IJRETINA - International Journal of Retina Jurnal Muara Medika dan Psikologi Klinis Occupational and Environmental Medicine Journal of Indonesia Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Journal of Indonesian Specialized Nutrition Ophthalmologica Indonesiana
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Length Of Time Return To Work In Workers With Low Back Pain And Associated Factors: Lamanya Waktu Kembali Bekerja Pada Pekerja Dengan Nyeri Punggung Bawah Dan Faktor Yang Berhubungan Tri Mawanti, Wening; Soemarko, Dewi S.; Kekalih, Aria
Binawan Student Journal Vol. 5 No. 3 (2023)
Publisher : Direktorat Penelitian, Pengabdian Masyarakat, Dan Kerjasama Universitas Binawan (DPPMK Universitas Binawan)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54771/bsj.v5i3.875

Abstract

Low back pain is one of the musculoskeletal disorders often associated to work. Based on previous research, 70.3% low back pain was found in manual handling workers and 22.98% in female nurses in hospital wards. The effects of low back pain are disability, decreased productivity and attendance rate, and loss of working hours. Returning to work as soon as possible after illness in a certain capacity is a highly recommended action. Until now in Indonesia there is no data on the length of time return to work on workers with low back pain and related factors. This study used cross-sectional design to determine the length of time return to work   and its relation to individual factors, work, and work environment. It used the Oswestry questionnaire and the population is workers who have low back pain and treated in a hospital, given sick leave, by the doctor as outpatient or inpatient. Workers with low back pain treated at the hospital (November 2016-April 2017), obtained a doctor's rest and or hospitalization letter amounting to 40 people (total sampling). The average value of the duration of return to work is 3 days (1-15 days) although clinical complaints have not fully disappeared. Factors relating to the length of the return to work were age (OR 9,71, 95% CI 1.08-87.31) and disability level before treatment (OR 2.50, 95% CI1.25-4.99). Length of time return to work due to low back pain is 3 days and has association  to age and disability level.
A Implementation of COVID-19 Preventive Healthy Lifestyle (PHL) among Administration Staff and its association with Health Consciousness and Occupational Factors: A Cross Sectional Study in Faculty Medicine Universitas Indonesia Tukimun, Suci Tria Meirisa; Kekalih, Aria; Purwito Adi, Nuri; Sumaryani Soemarko, Dewi; Ilyas, Muhammad
The Indonesian Journal of Community and Occupational Medicine Vol. 3 No. 2 (2023): ijcom
Publisher : ILUNI MKK FKUI and PRODI MKK FKUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53773/ijcom.v3i2.93.73-81

Abstract

Background: The COVID-19 pandemic has altered the pattern of human life toward a new life order,particularly in the office setting. Appeals, prohibitions, even large-scale social restrictions were implemented in order to decrease the cases. To cope with the rapid spread of the outbreak, citizens have to increase health consciousness and reduce their social interactions. The health consciousness require health protocols implementation. Ensuring high levels of compliance and several modifiable occupational risk factors in the office setting has been a challenge to manage the pandemic effectively. Methods: The research method used in this study is empirical research, by taking a problem-based approach to a behavioral approach namely health consciousness supported by primary data sourced from data sources. The data were obtained in October to November 2021. Results: When taken as a whole, the implementation of health protocols as part of the effort to prevent the spread of COVID-19 was relatively good; it's just that certain obstacles must be evaluated. The highest health consciousness scores were personal responsibility and health motivation. While the lowest of it were the psychological/inner state aspect and the health information and seeking usage. There was a positive correlation between the dimensions of health consciousness and several items of COVID-19 PHL (r > 0.3). The ease of applying COVID-19 PHL was significantly better for shift workers compared to non-shift workers, namely to severalitems of PHL. Based on the work pattern groups (WFH < 20 hours, WFH 20-40 hours and WFH > 40 hours, alternate to Work From Office (WFO)), there were no significance difference in the ease of implementation COVID-19 Preventive Healthy Lifestyle. Conclusion: Our results suggest that to effectively manage the pandemic, we should ensure that health consciousness is well-maintained, especially aspects of health information and seeking usage and psychological/inner state. Keywords: health consciousness, COVID-19 Preventive Healthy Lifestyle (PHL) at the workplace, shift work, work patterns during pandemic
Pharyngeal transit time in different consistency of food using Fiberoptic Evaluation of Swallowing Tamin, Susyana; Iqbal, Mochamad; Rachmawati, Elvie Zulka Kautzia; Yunizaf, Rahmanofa; Restuti, Ratna Dwi; Kekalih, Aria
Oto Rhino Laryngologica Indonesiana Vol. 52 No. 2 (2022): VOLUME 52, NO. 2 JULY - DECEMBER 2022
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v52i2.537

Abstract

ABSTRACTBackground: In Indonesia, no research has been carried out or reported on pharyngeal transit time and a view of the swallowing process in a sample without complaints of dysphagia using the Flexible Endoscopic Evaluation of Swallowing (FEES) method and using five food consistencies. Purpose: To obtain the value of pharyngeal transit time and a view of the swallowing process in subjects without dysphagia problems. Method: Twenty-eight subjects without dysphagia (based on Ohkuma’s Dysphagia Screening) underwent FEES to determine pharyngeal transit time and dysphagia profile based on leakage, standing secretion, residue, penetration, and aspiration. Result: The median value of pharyngeal transit time on puree consistency was 0.799(0.499-5.666), gastric rice 0.966(0.433-5.733), oatmeal 0.849(0.533- 4.399), thick liquid 0.982(0.399-4.633), thin liquid 0.566(0.366-1.366). The pharyngeal delay time on the puree consistency was 0.566(0.199-5.333), gastric rice 0.799(0.233-2.799), oatmeal 0.899(0.099-3.633), thick liquid 0.833(0.033-3.733), and thin liquid mean was 0.294 (± 0.232). The pharyngeal response time on the puree consistency was 0.566(0.167-1.300), gastric rice 0.583(0.300-2.934), oatmeal 0.583(0.367- 1.233), thick liquid 0.549(0.333-1.533), thin liquid 0.549(0.366-1.399). There was no standing secretion, pre-swallowing leakage, penetration, and aspiration found in FEES. A grade 1 residue was found in 3(10.7%) subjects of puree, in 2(7.2%) subjects of gastric rice, in 3(10.7%) subjects of oatmeal, and in 9(32.2%) subjects of thick liquid. Conclusion: There was no prolonged pharyngeal transit time, pre-swallowing leakage, standing secretion, penetration, and aspiration in all subjects without dysphagia complaints at all food consistencies. There was minimal residue within normal limits in some subjects. ABSTRAKLatar belakang: Di Indonesia, belum pernah dilaporkan penelitian mengenai waktu transit faring dan gambaran proses menelan pada sampel tanpa keluhan disfagia dengan menggunakan metode Flexible Endoscopic Evaluation of Swallowing (FEES) dan menggunakan lima konsistensi makanan. Tujuan: Penelitian ini bertujuan untuk memperoleh nilai waktu transit faring dan gambaran proses menelan pada subjek tanpa masalah disfagia. Metode: Dua puluh delapan subjek tanpa disfagia (berdasarkan Skrining Disfagia Ohkuma) menjalani FEES untuk menentukan waktu transit faring dan profil disfagia berdasarkan leakage, standing secretion, residue, penetration, dan aspiration. Hasil: Nilai median waktu transit faring pada konsistensi puree adalah 0,799(0,499-5,633), gastric rice 0,966(0,433-5,733), oatmeal 0,849(0,533-4,399), thick liquid 0.982(0.399-4.633), thin liquid 0.566(0.366- 1.366). Waktu tunda faring pada konsistensi puree adalah 0,566 (0,199-5.333), gastric rice 0,799 (0,233-2,799), oatmeal 0,899 (0,099-3,633), thick liquid 0,833 (0,033-3,733), dan rerata thin liquid 0,294 (± 0,232). Waktu respon faring terhadap konsistensi puree adalah 0,566 (0,167-1,300), gastric rice 0,583 (0,300-2,934), oatmeal 0,583 (0,367-1,233), thick liquid 0,549 (0,333-1,533), thin liquid 0,549 (0,366-1,399). Tidak didapati adanya leakage, standing secretion, penetration, dan aspiration pada pemeriksaan FEES. Residu grade 1 ditemukan pada 3 (10,7%) subjek puree, pada 2 (7,2%) subjek gastric rice, pada 3 (10,7%) subjek oatmeal, dan pada 9 (32,2%) subjek thick liquid. Kesimpulan: Tidak terdapat perpanjangan waktu transit faring, leakage, standing secretion, penetration, dan aspiration pada semua subjek tanpa keluhan disfagia dengan semua konsistensi makanan. Terdapat residu minimal dalam batas normal pada beberapa subjek.
E-Learning Readiness and Job Stressor of Elementary School Teachers in the Covid-19 Pandemic Dwianasari, Riani; Kekalih, Aria; Fitriani, Dewi Yunia; Soemarko, Dewi Sumaryani; Fuadi, Ahmad
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 6 No. - (2022): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v6i-.126

Abstract

Background: E-learning readiness became a new workload for teachers during the Covid-19 pandemic because of the obligatory online teaching. E-learning readiness comprises four factors: the readiness of technology, innovation, people, and self-development; and it might cause job stressors and affect teachers' performance. The research objective was to explore job stressors that influence teachers the most and how they might be associated with E-learning readiness. Method: The cross-sectional method assessed 186 teachers from public and private elementary schools in the urban city area in Jakarta. The data obtained from questionnaires: Teacher Stress Inventory (TSI) Boyle and E-learning Readiness (ELR) Aydin and Tasci. TSI assessed teachers' job stressors in five main components: workload, student behavior, professional recognition, time and resources, and interpersonal relationships. Results: Most teachers perceived readiness at e-learning (84.9%). E-learning readiness was a profound problem for female and non-classroom teachers. The dominant job stressors for teachers were workload (27%), professional recognition (22%), time and resources (21%), and student behavior (21%). The number of students influenced workload and professional recognition. Self-development was the prominent e-learning readiness factor associated with teacher job stressors, especially professional recognition. Conclusions: In urban areas like Jakarta, fifteen percent of teachers remain unprepared for e-learning teaching. The unpreparedness was related to the female gender and non-classroom teachers, who need e-learning skills training to improve their readiness and control job stressors for better teaching performance in a prolonged pandemic situation.
The SDGs Perspective of TeleDoVIA Reliability for Cervical Cancer Elimination in 2030: A Cross Sectional Study in Indonesia Widya Utami, Tofan; Nuranna, Laila; Purwoto, Gatot; Winarto, Hariyono; Fitriyadi Kusuma; Rizky Humairah , Inas; Faisha Rahma, Melly; Kekalih, Aria; Peters, Alexander AW
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 4 October 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i4.1956

Abstract

Objective: To describe the prevalence of HPV infection in women with negative Visual Inspection with Acetic Acid (VIA) and introduce Teleconsultation of Documented VIA (TeleDoVIA) as an objective test and provide a rationalization for recommending TeleDoVIA as a “high-performance” test for cervical cancer screening in lower resource settings, from SDGs perspective, to accelerate the achievement of second pillar elimination and the third SDGs target in 2030. Methods: This is a 7-year cross-sectional study. Subjects were recruited consecutively from several public and private health providers in Jakarta. VIA test was documented and consulted to the experts panel (TeleDoVIA). Negative VIA women underwent HPV-DNA testing using SPF10-DEIA-LiPA25 for PCR and electrophoresis. Results: A total of 1,397 negative VIA subjects were collected, consist of 52 HPV-DNA positive. False-negative of VIA was 3.7% (95% CI 0.027–0.047). Conclusion: VIA is a reliable screening method with a low false-negative rate. TeleDoVIA could be recommended as a reliable cervical cancer screening method in low resource settings such as Indonesia, which is in line with the third SDG: good health and well-being. Keywords: Southeast Asia < Asia; public health.
Non-dominant handgrip strength is associated with higher cardiorespiratory endurance and elevated NT-proBNP concentrations in ambulatory male adult outpatients with stable HFrEF Triangto, Kevin; Radi, Basuni; Siswanto, Bambang B.; Tambunan, Tresia FU.; Heriansyah, Teuku; Harahap, Alida R.; Kekalih, Aria; Katsukawa, Hajime; Santoso, Anwar
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1278

Abstract

Understanding the significance of handgrip strength is essential for identifying frailty in heart failure patients. The aim of this study was to identify the association between handgrip strength and cardiorespiratory endurance while highlighting the importance of the musculoskeletal system in cardiac rehabilitation for patients with heart failure. An observational cross-sectional study was conducted at Harapan Kita Hospital, Jakarta, Indonesia, from April 2022 to April 2023, among patients with heart failure with reduced ejection fraction (HFrEF) attributed to cardiomyopathy or coronary artery disease. Patients were classified by a 6-minute walk test (6MWT) distance into <400 meters (low endurance) or ≥400 meters (high endurance). The short physical performance battery (SPPB), handgrip strength, ultrasonographic forearm muscle thickness, left ventricle ejection fraction, tricuspid annular plane systolic excursion, and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels were measured. Results indicated significant differences in non-dominant handgrip strength, gait speed, and sit-to-stand SPPB scores between patients achieving a 6MWT distance of ≥400 meters and those below this threshold, with values of 31.11±6.88 kg vs 27.66±6.66 kg (p=0.049), 0.52±0.08 m/s vs 0.61±0.13 m/s (p=0.001), and 10.71±2.47 seconds vs 12.85±4.11 seconds (p=0.014), respectively. Stronger non-dominant handgrip strength (>30 kg) was associated with higher endurance (odds ratio (OR): 3.80; 95%CI: 1.35–10.67; p=0.010) and thicker forearm muscles (>1.9 cm) as measured by ultrasonography (AUC: 0.713; 95%CI: 0.585–0.840, p=0.001). In conclusion, a cut-off of ≤30 kg for non-dominant handgrip strength could effectively stratify the male patients into a lower endurance group (6MWT ≤400 meters), which is associated with elevated NT-proBNP levels and reduced forearm muscle thickness.
Protokol Latihan BEST yang Disesuaikan dalam Rehabilitasi Gagal Jantung Triangto, Kevin; Radi, Basuni; Siswanto, Bambang Budi; Tambunan, Tresia Fransiska Ulianna; Heriansyah, Teuku; Harahap, Alida Rosita; Kekalih, Aria; Ambari, Ade Meidian; Dwiputra, Bambang; Desandri, Dwita Rian; Katsukawa, Hajime; Santoso, Anwar
Jurnal Kardiologi Indonesia Vol 45 No 3 (2024): July - September, 2024
Publisher : The Indonesian Heart Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30701/ijc.1738

Abstract

Introduction Heart failure with a reduced ejection fraction (HFrEF) significantly contributes to global morbidity and mortality, necessitating effective rehabilitation programs. Exercise-based rehabilitation improves functional capacity and quality of life in HFrEF patients, though responses vary. The tailored BEST (Breathing, Endurance, and Strengthening) exercise protocol addresses both cardiac and extracardiac rehabilitation, benefiting all patients regardless of response status. This study evaluated the protocol's effects on HFrEF patients and classified responses based on VO2max changes. Methods In this etiologic study with prospective cohort design, all participants underwent a three-month cardiac rehabilitation program using the BEST Exercise Protocol. Assessments included the 6-minute walk test (6MWT), short physical performance battery (SPPB), handgrip strength, chest expansion, ultrasonographic measurements, and NT-proBNP levels before and after the intervention, with statistical comparisons made within and between groups. Groupings of responder level will be reliant on 6MWT distance achievement at the end of the program, with ≥6% improvement classified as good responders. Results Out of 107 HFrEF patients (median age 55 years, ejection fraction 29.50±7.34%), 63.56% were good responders and 36.44% were poor responders (<6% improvement). Good responders showed significant improvements in most extracardiac parameters, including a 20% increase in 6MWT distance (470.96±69.21 meters post-rehabilitation), chest expansion, handgrip strength, and SPPB scores (p<0.001 for all). Poor responders also improved in chest expansion, sit-to-stand time, and postural balance, with minor 6MWT gains (407.33±72.50 meters). NT-proBNP levels decreased in both groups but were not statistically significant (p=0.288 and 0.368 for good and poor responders, respectively). Conclusion The tailored BEST Exercise Protocol offers substantial cardiac and extracardiac benefits for HFrEF patients by enhancing functional capacity and muscle strength. Both good and poor responders exhibited significant improvements, indicating the protocol's broad applicability. However, the lack of statistically significant NT-proBNP reduction suggests further studies on cardiac biomarkers are needed. The 6MWT provides accessible rehabilitation insights, though more precise evaluations like Cardiopulmonary Exercise Testing (CPET) can offer clearer insights into cardiopulmonary adaptations.
Comprehensive Histopathological Properties of Dartos Tissue Associated with Hypospadias Severity and Chordee: A Prospective Study Raharja, Putu Angga Risky; Birowo, Ponco; Rachmadi, Lisnawati; Wibowo, Heri; Kekalih, Aria; Duarsa, Gede Wirya Kusuma; Wahyudi, Irfan
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 8 No. - (2024): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v8i-.243

Abstract

Background: The cause of chordee in hypospadias is not fully understood. Dartos fascia resection has been shown to correct penile curvature, suggesting its potential involvement. This study aimed to evaluate the histopathological properties of dartos tissue and their association with hypospadias severity and chordee.Methods and Materials: Dartos tissue samples were collected from 37 children with hypospadias and ten controls undergoing circumcision between March and October 2024. Histopathological analysis using hematoxylin-eosin and Masson’s trichrome staining assessed for collagen, smooth muscle, and vascular density. Assessment and quantification of all histopathological components were blinded. Results: The hypospadias group showed lower collagen density (60.85±6.75% vs. 67.31±4.61%; p=0.003) and higher smooth muscle density (7.34±4.92% vs. 2.51±2.24%; p<0.001) compared to controls, with no significant difference in vessel density. Sub-analysis showed severe chordee was linked to lower collagen density compared to mild (Mean Difference [MD] -6.24±2.41%; p=0.014) and moderate chordee (MD -5.73±2.54%; p=0.031). Conclusions: The dartos tissue in hypospadias patients exhibited lower collagen density and higher smooth muscle density, with chordee severity specifically linked to decreased collagen density.
Exploring the Relationship Between Comprehensive Respiratory Assessment and Intra-Extracardiac Biomarkers in Heart Failure Rehabilitation Triangto, Kevin; Radi, Basuni; Siswanto, Bambang B.; Tambunan, Tresia FU.; Heriansyah, Teuku; Harahap, Alida R.; Kekalih, Aria; Katsukawa, Hajime; Santoso, Anwar
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 8 No. - (2024): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v8i-.248

Abstract

Introduction: Heart failure with reduced ejection fraction (HFrEF) is well-known as a systemic disease that involves cardiac and extracardiac issues, with respiratory function playing on of the key role in rehabilitation prognosis. Biomarkers such as soluble suppression of tumorigenicity 2 (sST2), myostatin, miRNA-133, and NT-proBNP indicate disease progression. Notably, sST2, which is also produced by the lungs, predicts heart failure outcomes. This study examines the relationship between comprehensive respiratory assessments (e.g., diaphragmatic ultrasonography, spirometry) and intra-extracardiac biomarkers to improve rehabilitation strategies. Methods: Sixty-nine HFrEF patients underwent respiratory evaluations, including diaphragmatic ultrasonography, spirometry, chest expansion measurements, and a six-minute walking test (6MWT). Biomarkers assessed were sST2, myostatin, miRNA-133, and NT-proBNP. Associations between respiratory parameters and biomarkers were analyzed using t-tests and correlation analyses. Results: The median age was 56 years, and 33 (47.82%) of the subjects had diaphragmatic dysfunction, resulting in poorer 6MWT performance (378.03±58.15 m vs 409.75±63.65 m, p=0.017) and other parameters. Superior chest expansion negatively correlated with sST2 (r=−0.387, p=0.001) and positively with miRNA-133 (r=0.442, p<0.001). Similar results were found for inferior chest expansion. No significant correlations were observed for other biomarkers. Conclusion: This study highlights strong associations between chest expansion and sST2/miRNA-133, suggesting that incorporating respiratory assessments and training into HFrEF rehabilitation could enhance outcomes by addressing cardiorespiratory insufficiencies. Given sST2's predictive value for heart failure prognosis, these findings support a multi-component rehabilitation strategy incorporating respiratory training, such as aerobic and inspiratory muscle exercises, to enhance cardiopulmonary outcomes. This integrated approach offers promise for future HFrEF rehabilitation protocols.
Radiological and histological assessment of a novel interlocking three-dimensional miniplate for mandibular angle fractures: an animal study Kreshanti, Prasetyanugraheni; Noviana, Deni; Priosoeryanto, Bambang Pontjo; Kekalih, Aria; Rahyussalim; Supriadi, Sugeng; Hatibie, Mendy Juniaty; Sukasah, Chaula Luthfia
Medical Journal of Indonesia Vol. 33 No. 4 (2024): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247567

Abstract

BACKGROUND Open reduction and internal fixation are considered the gold standard for managing mandibular fractures, as they effectively restore anatomical structure and functionality. Three-dimensional (3D) miniplates were developed to obtain a geometrically stable structure. However, the rigid structure of 3D miniplate may cause screw holes to be located within the fracture lines or directly above important anatomical structures. Hence, we have developed customizable interlocking 3D miniplates that allow for modifications in the configuration of the horizontal miniplates and vertical cross-struts to meet specific requirements. METHODS This study included 24 goats divided into 2 groups: interlocking 3D miniplate and standard plate. Each group was further divided into subgroups sacrificed on Days 5, 28, and 56. Radiological assessments were performed to evaluate bone, muscle, peri-implant bone, and peri-implant muscle density. Histological assessments were performed using Masson's trichome (MT) for bone healing evaluation and hematoxylin and eosin (H&E) staining for biocompatibility. RESULTS Radiological assessment indicated an increase in density across all measured parameters from Day 5 to 56. Histological evaluation from MT staining showed a significantly higher fibrocartilage in the interlocking 3D miniplate group (6.109%, IQR 1.453–10.828) compared to standard plate (1.311%, IQR 0.636–2.553; p = 0.001). Furthermore, H&E staining showed significantly higher inflammatory cell counts in the standard group on Days 28 and 56 compared to the interlocking 3D miniplate group (p = 0.027). CONCLUSIONS This study concluded that the interlocking 3D miniplate showed better bone healing properties and biocompatibility than the standard plate.
Co-Authors Achmad Fauzi Kamal Addin Trirahmanto Adiningsih Sri Lestari Afrionaldi Suparman Agi Satria Putranto Agiananda, Feranindhya Agus D. Susanto Agus Rizal Ardy Hariandy Hamid, Agus Rizal Ardy Hariandy Ahmad Aulia Ahmad Fuadi Ahmad Syafiq Aldri Frinaldi Aleddin, Rommel Alexander AW Peters Alida Roswita Harahap Alma Thahir Pulungan Ambari, Ade Meidian Amendi Nasution Amilya Agustina Amir Shidik Amir Shidik Amitya Kumara Amitya Kumara Andi Arus Victor Andrijono Angela BM Tulaar Angkoso, Heru Aninditha, Tiara Anis Karuniawati Anita Ratnawati Anitasari Kusumawati Antonius H. Pudjiadi Anwar Jusuf Anwar Santoso Aprilya, Dina Arthur Garson Aryono Hendarto Asmarinah Astrid Sulistomo Astrid Sulistomo Aziza G. Icksan Badriul Hegar Badriul Hegar Bambang Budi Siswanto Bambang Pontjo Priosoeryanto Bambang Supriyatno Basrowi, Ray Wagiu Basuni Radi Batubara, Jose Benjamin Ngatio, Benjamin Betharia Sonata Butarbutar Bethy Suryawathy Hernowo Bondan Harmani Bondan Harmani Boy Hidayat Budhi Antariksa Budi Sampurna Budi Wiweko Budiman Bintang Prakoso Bustamam, Alhadi Canintika, Anissa Feby Cepi Teguh Pramayadi Chaidir Arif Mochtar Cut Putri Samira Damayanti Rusli Sjarif Danny Rasjiid Garna Darmawan, Irene Darwis, Patrianef Deni Noviana Denta Aditya Episana Desandri, Dwita Rian Dewi Friska Dewi Friska Dewi Sumaryani Soemarko Dewi Sumaryani Soemarko Dewi Wulandari Dewi Yunia Fitriani Dewi, Fitriya Nur Annisa Dialika Dialika Diani Kartini Dilawar, Ismail Dwikora Novembri Utomo Dwiputra, Bambang Effendi, Haikal Elisna Syahruddin Elisna Syahruddin Elvioza Elvioza Elvioza Elvioza Endang Parahyanti Erlina Burhan Etty Rekawati Fachruddin, Ismi Irfiyanti Faisal Yunus Faisha Rahma, Melly Faraby Martha Feni Fitriani Ferius Soewito Ferry Sandra Firdaus, Najmarani Devi Fitri Fujiana Fitri Octaviana Fitriyadi Kusuma Gatot Purwoto Gede Wirya Kusuma Duarsa Ginting, Tribowo T. Halim, Kelvin Hanny Nilasari Hansen Angkasa Harahap, Alida R. Harahap, Alida Rosita Hariyono Winarto Harsono, Hasto Hartanto, David Dwiadiputra Hartono Gunardi Hartono Gunardi Haswinzky, Rose Amalia Hatibie, Mendy Juniaty Helda Khusun Helda Khusun Helena Turnip Hendriko Heri Suroto Heri Wibowo Herqutanto Herqutanto - Herwanto Herwanto Hesti Lestari Hidayat, Boy I Gusti Lanang Sidiartha I Nyoman Murdana Ibrahim Basir Ida Parwati Idhil, Andi Nurul Isri Indriany Idqan Fahmi Idqan Fahmi Ika Citra Susanti Ika Karlina Idris Imam Subekti Imami Nur Rachmawati Ina Susianti Timan Indiarto Wityawan Indra Hardjono Indrasari, Nuri Dyah Indri Aulia Inne Yuliawati, Inne Iqbal, Mochamad Irfan Wahyudi Iris Rengganis IRWANTO Isep Supriyana Ismail Hadisoebroto Dilogo Ismet, Mohamad F. Iwan Dwiprahasto Iwan Dwiprahasto Jeanne Adiwinata Pawitan Jeo, Wifanto S. Jeo, Wifanto Saditya Johan, Anita Judith N. Anastasia Junaiti Sahar Junita Indarti Kamil, Radhita F. Kanadi Sumapradja Karnasih, Artasya Kartika, Emiliana Katsukawa, Hajime Kayika, I Putu Gede Kemal N. Siregar Kreshanti, Prasetyanugraheni Kurniawan, Kristian Kusmarinah Bramono Kusnadi, Dana S. Laila Nuranna Latifah , Suci Lesmana, Elvira Levina Chandra Khoe Liem Jen Fuk Lisa Hasibuan Lisnawati Lisnawati Rachmadi Luh Ade Wiradnyani Luh K Wahyuni Luh Karunia Wahyuni, Luh Karunia Lukman Edwar M Ilyas M. Dio Syaputra M. Sidik Marcellus Simadibrata Mardianto, Umar Marsen Isbayu Putra Maulanisa, Sinta C. Maulia Fitra Purnama Maulia Fitra Purnama Meilania Saraswati Meilinda, Astrid Melva Louisa Mila Maidarti Mochamad Iqbal Moretta Damayanti Muchtaruddin Mansyur Muhamad Sidik Muhammad Ilyas Muhammad Ilyas Muhammad Sidik Muhammad Soffiudin Mulyadi M. Djer Mulyantara, Irwan Murni, Indah K. Najib Advani Nasrun, Martina WS. Natadisastra, Raden Muharram Novia Rahayu Nur Ahlina Damayanti Nuraini I Susanti Nuri Purwito Adi Nuri Purwito Adi Nurjati Chairani Siregar Nurmiati Amir Nury Nusdwinuringtyas Nury Nusdwinuringtyas Nury Nusdwinuringtyas Nyoman Murdhana Oktalia, Arisda Oktavia, Nikken Rima Ova Emilia Pandelaki, Jacub Paulus Daniel Sahanggamu Peggy Sunarjo Piprim B. Yanuarso, Piprim B. Ponco Birowo Pramaningasih, Maelissa Prasandhya Astagiri Yusuf Pratama, Dennis W. Prayangga, Regina Primariadewi Rustamadji Purba, Herdiman Bernard Puspaseruni, Putri Air Puspita Eka Wuyung Putra, M. Arza Putranto, Agi S. R. Muharam Rachmanto, Ary Rachmawati, Elvie Zulka Kautzia Raden Muharam Natadisastra Radiana Dhewayani Antarianto Raditya Pratama Rahadiani, Nur Raharja, Putu Angga Risky Rahayu, Tri Rahmanofa Yunizaf Rahyussalim Ratna Dwi Restuti Restuti, Ratna Dwi Retno Asti Werdhani Reynaldo Reynaldo Reynaldo Reynaldo, Reynaldo Riani Dwianasari, Riani Rilanda, Risa Rini Andriani Rini Andriani Rini Sekartini Risky Dwi Rahayu Rita Hadi Widyastuti Riza Sahyuni Rizky Humairah , Inas Rosa Tatun Roy Dwi Indra Rubiana Sukardi, Rubiana Rusli, Noer Triyanto S. Soemarko, Dewi Saleha Sungkar Sali Rahadi Asih Salmarezka Dewiputri Samjunanto, Achmad Sandra Widaty Sari, Siti Maulidya Saunar, Rofi Y. Sawitri Darmiati Seala Septiani Selly C Anggoro Setia Wati Astri Shidik, Muhammad Sihombing, Masri Sinaga, Kezia M. Siregar, Sun Parkuseg Siskawati, Yulia Siste, Kristiana Sri L. Menaldi Sri Linuwih Susetyo Wardhani, Sri Linuwih Susetyo Sri Wahdini Sugeng Supriadi, Sugeng Sugiharto, Bobby Suhartono, Raden Suhendro Suhendro Sujudi, Yufanti Sukasah, Chaula Luthfia Sulastri, Nuni Sulistomo, Astrid Supriatna, Novianti Suratih, Ni Made Desy Susanti, Dhama S. Susanti, Nuraini I Susanti, Nuraini I Syahrial MH Syntia Nusanti Syntia Nusanti Syntia Nusanti Syntia Nusanti Syska Widyawati Syska Widyawati Tambunan, Tresia Fransiska Ulianna Tambunan, Tresia FU. Tamin, Susyana Tarigan, Immanuel N. Teuku Heriansyah, Teuku Theddeus O. H. Prasetyono Tirza Z Tamin Tjhin Wiguna Toar J.M. Lalisang Tran Thi Hai Tresia Fransiska Uliana Tambunan Tresia Fransiska Ulianna Tambunan Tri Mawanti, Wening Tri Rahayu Tri Rahayu Tri Rahayu Triangto, Kevin Trinovita Andraini Trishna, Alya R. Tukimun, Suci Tria Meirisa Utami, Diah S. Utami, Sri Anidyo Utami, Tofan Widya Vanto, Yoni Velyani, Dyani Pitra Vetnizah Juniantito Viscanita Viscanita W. Roestam, Ambar Wahmurti, Tuti Wahyu Widodo Wardhani, Rizky Kusuma  Wibisono, Sasanto Wibowo, Suryo Widjajalaksmi Kusumaningsih, Widjajalaksmi Widura Imam Mustopo, Widura Imam Widya Utami, Tofan Winata, Vera Wresti Indriatmi B. Makes Yati Afiyanti Yayi Suryo Prabandari Yefta Moenadjat Yoga Devaera Yudan Whulanza Yulian, Erwin D. Yulian, Erwin Danil Yundari, Yundari Yunizaf, Rahmanofa Yusra Yusra Yusra