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Journal : PROSIDING SEMINAR KIMIA

SKRINING FITOKIMIA DAN POTENSI AKTIVITAS ANTIOKSIDAN EKSTRAK METANOL DAUN SINGKIL (Premna corymbose Roxb & Willd.) DENGAN METODE DPPH (1,1-diphenyl-2-picrylhydrazil ): A MINI REVIEW Dewi, Camelia Eugenia; Saleh, Chairul; Daniel, Daniel; Magdaleni, Agustina R.
PROSIDING SEMINAR KIMIA Vol 2 No 2 (2024): Prosiding SNKT III 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Singkil leaves (Premna corymbose Roxb & Willd.) are a plant that is widely found in Kalimantan, and usually grows in the yard of houses or plantations. A research on phytochemicals screening and antioxidant activity test of singkil leaves (Premna corymbose Roxb & Willd.) using DPPH (1,1- diphenyl-2-picrylhydrazyl) method had been conducted. Test for alkaloids, triterpenoids/steroids, phenolic, flavonoids, saponins, and quinone were included in phytochemical screening. The results of the literature show that the methanol extract exhibits antioxidant activity in the strong category, which has an IC50 value of 20.66 μg/ml. Methanol extract of singkil leaves (Premna corymbose Roxb & Willd.) has potential as an antioxidant. Keywords: Singkil leaves (Premna cordifolia Roxb.), phytochemical screening, antioxidant, DPPH
POTENTIAL ANTIOXIDANT ACTIVITY OF METHANOL EXTRACT OF SINGKIL LEAF (Premna cordifolia Roxb.) USE DPPH METHOD: A MINI RIVIEW Firmansyah, Muchammad Ravi; Daniel, Daniel; Marliana, Eva
PROSIDING SEMINAR KIMIA Vol 2 No 1 (2023): Prosiding SNK 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Singkil leaves (Premna cordifolia Roxb.) are a plant that is widely found in Kalimantan, and usually grows in the yard of houses or plantations. The antioxidant activity test of methanol extract from Singkil leaves (Premna cordifolia Roxb.) has been done. This research aims to determine the antioxidant properties of methanol extract from leaves. Based on the results of the phytochemical test, it is known that the methanol extract contains alkaloids, flavonoids, phenolics, steroids and triterpenoids. The results of the literature show that the methanol extract exhibits antioxidant activity in the "Strong" category, which has an IC50 value of 77.46 mg/L. Methanol extract of singkil leaves (Premna cordifolia Roxb.) has potential as an antioxidant. Keywords : Singkil leaves (Premna cordifolia Roxb.), antioxidant, DPPH
REVIEW ARTIKEL: PENAPISAN FITOKIMIA DAN POTENSI AKTIVITAS BIOLOGIS TANAMAN BAJAKAH (Uncaria cordata (Lour.) Merr.) Farhany, Farhany; Saleh, Chairul; Daniel, Daniel
PROSIDING SEMINAR KIMIA Vol 2 No 2 (2024): Prosiding SNKT III 2023
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Bajakah (Uncaria cordata (Lour.) Merr.) is an endemic plant to Kalimantan which is widely used as medicine. Various studies have been conducted regarding the phytochemical content and biological activity of Bajakah. Phytochemical screening was carried out for the content of alkaloids, flavonoids, polyphenols, triterpenoids, steroids, saponins, and tannins. Literature studies show that Bajakah has antioxidant activity within ethanol fraction with a very strong capacity as indicated by an IC50 value of 49.22 ppm, within the nhexane fraction with a medium capacity as indicated by an IC50 value of 108.22 ppm, and within ethyl acetate fraction with a medium capacity as indicated by an IC50 value of 130.30 ppm. Bajakah is also known to have antihyperuricemia activity by reducing uric acid levels at extract doses of 5.3 mg/30gBW, 10.6 mg/30gBW, and 21.2 mg/30gBW. Anticholesterol activity was indicated by reducing cholesterol levels at extract doses of 5.3 mg/30grW (11.45%), 10.2 mg/30grW (12.89%), and 21.2 mg/30grW (21.05%). Antiinflammatory activity was showed by testing the ethyl acetate extract of Bajakah stem at doses of 200 and 400 mg/kgBW. The acute toxicity test showed an LD50 value of >5000 mg/kgBW; indicating that the butanol fraction of Bajakah is relatively harmless and has potential as a standardized herbal medicine (OHT). Keywords : Uncaria cordata (Lour.) Merr.), phytochemical screening, bioassay
MINI RIVIEW: POTENSI ASAM MALAT (2-hydrobutanedioic-acid) DAN TURUNANNYA SEBAGAI SURFAKTAN Rachmat, A. Khafifah Dwi; Daniel, Daniel; Pasaribu, Subur P.
PROSIDING SEMINAR KIMIA Vol 3 No 1 (2024): Prosiding SNK 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Malic acid (2-hydrobutanedioic-acid) is a dicarboxylic acid (carboxylic acid) which is generally found in many apples. Several malic acid derivatives have been synthesized through esterification and amidation reactions, including methyl malate, maleyl oleate and maleyl glutamide. Based on the results of FT-IR analysis of malic acid, it is known that there is an absorption peak at wave number 3448.72 cm¬-1 indicating the presence of an alcohol group and an absorption peak at wave number 1720.50 cm-1 indicating the presence of a carboxylic group. In methyl malate, it is known that in the wave number area of ​​1735.93 cm-1, stretching vibrations of the C=O ester carbonyl group occur. In maleyl oleate, the absorption in the wave area of ​​1743.65 cm-1 is a typical absorption from the stretching vibration of C=O ester. In maleyl glutamide, it is known that there is absorption at the peak wave number of 3425.58 cm-1 which is the stretching vibration of the NH (amide) group. The results of several literatures explain that the malic acid derivative, namely methyl malate, has an HLB value of 11.2 and can be used as an O/W (Oil in Water) emulsifier. The HLB value of maleyl oleate has a value of 4.61 which can be used as a W/O (Water in Oil) emulsifier and for maleyl glutamide the HLB is 14.84 which can be used as an O/W (Oil in Water) emulsifier. Therefore, malic acid derivatives have potential as materials for surfactant synthesis. Keywords: Malic Acid, Esterification and HLB (Hydrophilic Lipophilic Balance).
Co-Authors Abdul Hamid A. Yusra Abdul Latief Abdurizal Arsyad, Syech Geopandu Adi Suyatno Agatha, Septian Ahmad Ridha Akbar, Fath Ali Amin, Abdul Rachmad Zahrial Amiruddin Amiruddin Amrazi Zakso ANDI ACO AGUS Andi Muhammad Fadhal Hiqh.T Pangera Andreas Saputra, Andreas Angelita, Maya Anis Chariri Annisa Purbasari, Annisa Athaillah, Farida Batan, Alfrida Bihairi Hadi, Ricky Lutfi Br Ginting, Survina Osalia C. Pickerling Cahya, Lisye Mareta Cendana, Colleen Chairul Saleh Chandra Wijaya Christiyanto, Laurensius Erdin Christopher, Arvin Damanik, Justin Gamaliel Dedhi Yustendi Dewi, Camelia Eugenia Dewi, Ezra Shandra Dhita Wahyu Anggraeni, Dhita Wahyu Dwi Agustina Ermawati Ermawati Erwin Erwin Eva Marliana, Eva Farhany, Farhany Fathurrohman, Reza Fazhar Sumantri Fellyanto, Fellyanto Ferdian, Riyan Ferdian, Ryan Fila Sasmita Firmansyah, Muchammad Ravi Fredy Purnomo Frengki Frengki, Frengki Gaanty Pragas Maniam, Gaanty Pragas Hartono, Eric Hasibuan, Serepina Yoshika Hasriati Hasriati, Hasriati Hendrawan Armanto Hermanto Hermanto Hidayat, Farah Amalia Hiyahara, Irfan Ashari Idham Khalid Imran Imran Indra, Natal Iwan Ramadhan Jap Tji Beng Jonatan, Jonatan Juliana, Eva Junianto Wika Adi Pratama Justin, Justin Kirana, Stephani Nindya Kumahara, Wien Kurniati, Triani Larosa, Setiaman Latumahina, Bill Samuel Lelunu, Sapta Leslivania, Monika Liangga, David Lukman Hakim M Ezar Al Rivan M. Hasan Magdaleni, Agustina R. Magdaleni, Agustina Rahayu Makmur, Ali Malina, Khaira Manisha, Manisha Margareta, Serlen Marpaung, Franky Hadinata Maylina, Ajeng Chandra Meiliana, Evita Meriyani, Susi Michael Michael Mochammad Imron Awalludin Moron, Maria Selvi Muhammad Jalaluddin, Muhammad Muhammad Nadir Mulyono, Romi Kurniawan Agni Muttaqien Bakri, Muttaqien Nataniel Tandirogang Noni Zakiah Noor Hindryawati, Noor Nora Usrina Nugrahanto, Cornelius Septian Nurhidayah, Annisa Nurleni, Nurleni NURLIANA NURLIANA Nurmadewi, Dita Nurmawan, Mardatungga Octa Maria Sihombing Octavianus Octavianus, Octavianus Olivia, Nia Panannangan, Josua K. Partomuan Simanjuntak Pentagon, Pentagon Pontan, Darmawan Pratama, Ellen Putri, Erika Ardya Mesia Rachmat, A. Khafifah Dwi Rachmat, Zul Rahmawati, Rahmawati Rakhmad, Rakhmad Ravensca, Irene Riandi, Lian Varis Rindawati, Novi Riska Riska Rismawati Rismawati Riyanto, Rahmat Fajar Rosalina Putri, Kesia Roslizawaty Roslizawaty, Roslizawaty Rosmaidar Rosmaidar, Rosmaidar Rustiyarso, Rustiyarso Ryn Pratiwi, Djihan Saibun Sitorus Sandra, Putri Ayu Sanjaya, Regi Sara Ruhghea Sari, Dea Kurnia Sari, Wahyu Eka SATRIYAS ILYAS Sembiring, Rinawati Sigit, Miarsono Sikwan, Agus Silvia Monica Sisilia, Desy Sitompul, Citra Uli Soma, Yolanda V. A Sormin, Hendro Jatmiko Subagyono, R.R. Dirgarini Julia Nurlianti Subur P Pasaribu Sucipto, Rakhmat Hadi Sudrajat Sudrajat Sumeru, Indrawati Suteja, Mekar Sari Suzzana Winda Artha Mustika Swastika, Rahayu Syafrida, Yuni Tandjung, Muhammad Akbar Toibah Umi Kalsum TONE, KAMARUDDIN Tony Tony Torro, Supriadi Variani, Joanna Rika Vedro, Vedro Vera Methalina, Vera Vincent Tristan, Radick Viny Christanti M Wardhani, Lailia Dwi Kusuma Wardoyo, Arif Wasino Wasino Widiastiani, Nindry Sulistya Wirya, Wirya Yenni Yusriani Yohanes Bahari Yonas, Yonas Yunita, Risna Zulkifli Zulkifli Zulkifli, Baidillah Zuri Astari