Article Per Year (5 Year)
p-Index From 2021 - 2026
10.308
P-Index
This Author published in this journals
All Journal Jurnal Pendidikan dan Pembelajaran Khatulistiwa (JPPK) Seminar Nasional Teknik Kimia Kejuangan Fakultas Ekonomi PUJANGGA: Jurnal Bahasa dan Sastra PROSIDING SENATEK FAKULTAS TEKNIK UMP Jurnal Ampere The Indonesian Biomedical Journal Jurnal Manajemen Pelayanan Publik Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Penelitian Pendidikan IPA (JPPIPA) JURNAL PENDIDIKAN TAMBUSAI AL-HAYAT: Journal of Biology and Applied Biology Jurnal Literasiologi Eksakta : Berkala Ilmiah Bidang MIPA PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JURNAL SURYA ENERGY Jurnal Pendidikan Teknologi Pertanian Transformasi : Jurnal Pendidikan Matematika dan Matematika Babali Nursing Research INCARE Akrab Juara : Jurnal Ilmu-ilmu Sosial STUDI PELAKSANAAN SELFMEDICATION PADA PENDERITA DIARE BERDASARKAN TINGKAT PENGETAHUAN MASYARAKAT PESISIR KECAMATAN SOROPIA KABUPATEN KONAWE Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) Community Empowerment Jurnal Nuansa Akademik: Jurnal Pembangunan Masyarakat Devotion: Journal of Research and Community Service Narra J Jurnal Media Informatika Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal Abdimas Ekonomi dan Bisnis Jurnal Abdimas Komunikasi dan Bahasa BIOCHEPHY: Journal of Science Education Al-Idzaah : Jurnal Dakwah dan Komunikasi AKM: Aksi Kepada Masyarakat J-KIP (Jurnal Keguruan dan Ilmu Pendidikan) Jurnal Ilmiah Arsitektur Jurnal Teknik Elektro Eduthink: Jurnal Pemikiran Pendidikan Islam COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Jurnal PRIMED:Primary Education Journal atau Jurnal Ke-SD An Jurnal Sains dan Teknologi Journal Evidence Of Law Seulanga : Jurnal Pendidikan Anak Makara Journal of Science Tsaqofah: Jurnal Penelitian Guru Indonesia YASIN: Jurnal Pendidikan dan Sosial Budaya Indonesian Journal of Medical Chemistry and Bioinformatics Jurnal Penelitian Ilmu Pendidikan Indonesia Jurnal Ruaya : Jurnal Penelitian dan Kajian Ilmu Perikanan dan Kelautan Mestaka: Jurnal Pengabdian Kepada Masyarakat Eduvest - Journal of Universal Studies Innovative: Journal Of Social Science Research Jurnal Pengabdian Masyarakat Bangsa Jurnal Pengabdian Inovasi Masyarakat Indonesia International Journal of Trends in Accounting Research Media Akuntansi Perpajakan Waluya The International Science of Health Journal Cendikia Pendidikan GEMBIRA (Pengabdian Kepada Masyarakat) TACET Jurnal Pendidikan dan Kajian Seni Indonesian Journal of Community Empowerment Ta'dibiya: Jurnal Agama dan Pendidikan Islam Jurnal Imiah Pengabdian Pada Masyarakat (JIPM) Indonesian Journal of Biomedicine and Clinical Sciences Journal of Social Work and Science Education Tadibiya; Jurnal Agama dan Pendidikan Islam Journal of Islamic Elementary Education Indonesian Journal of Jamu Aspirasi: Jurnal Ilmiah Administrasi Negara Zad Al-Ummah: Jurnal Pengabdian Masyarakat
Fadilah Fadilah, Fadilah
Jurusan Teknik Kimia, Fakultas Teknik, Universitas Sebelas Maret Jl. Ir. H. Sutami Surakarta, 57126
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

Published : 94 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Narra J

 1 
Impact of semen insemination on the vaginal microbiome profile of candidiasis rat model: A preliminary forensic study on sexual violence evidence Iswara, Raja AFW.; Hestiantoro, Andon; Budiningsih, Yuli; Werdhani, Retno A.; Birowo, Ponco; Wuyung, Puspita E.; Fadilah, Fadilah; Afandi, Dedi
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1256

Abstract

Sexual violence, including sexual intercourse, can occur in women experiencing vaginal discharge, particularly in cases of vaginal candidiasis. In candidiasis, the vaginal microbiome undergoes changes that could serve as a diagnostic indicator or as evidence of sexual activity.  The aim of this study was to assess the effects of semen insemination on the vaginal microbiome profile of candidiasis rats and to determine its forensic investigations in cases of sexual violence.  An experimental study was carried out using Wistar strain rats (Rattus norvegicus), consisting of four male rats (for spermatozoa donors) and twenty-four female rats. The female rats were divided into four groups: normal condition (control), normal condition post-semen insemination, candidiasis rats, and candidiasis rat post-semen insemination. Vaginal microbiome profiles were examined for each group, using alpha diversity (Chao 1, Shannon, Simpson, and Faith PD indices) and beta diversity (Bray Curtis, Jaccard, Unweighted Unifrac and Weighted Unifrac indices). Data were analyzed using the Kruskal-Wallis test for alpha diversity and the PERMANOVA test for beta diversity. The vaginal microbiome profiles of normal and candidiasis rats showed no significant differences (p>0.05). In candidiasis rats, the microbiome predominantly consisted of the Eukaryota kingdom, particularly Candida albicans. Semen insemination did not significantly affect the vaginal microbiome profile of candidiasis rats in the short term (p>0.05). However, the study highlights that the presence of Eschericia-Shigella, Roseomonas, and Archaea in the vaginal microbiome post-semen insemination potentially serves as an indicator of infection or sexual activity in forensic contexts.
DNA methylation profiles for breast cancer subtype classifications: A translational study from microarray to methylation-specific PCR (MSP) Panigoro, Sonar S.; Paramita, Rafika I.; Wanandi, Septelia I.; Fadilah, Fadilah; Wibisana, I GNG.; Sutandyo, Noorwati
Narra J Vol. 5 No. 1 (2025): April 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i1.1364

Abstract

Breast cancer subtypes can be categorized based on their gene expression profiles using immunohistochemistry into Luminal A, Luminal B, human epidermal growth factor receptor 2-positive (HER2+), and triple-negative breast cancer (TNBC) subtypes. However, immunohistochemistry has certain limitations that can lead to misclassification. DNA methylation is an epigenetic modification, and changes in the promoter region can alter gene expression and the quantity of functional protein synthesized, disrupting gene function. The aim of this study was to identify DNA methylation biomarkers for subtype classification in breast cancer using microarray and methylation-specific polymerase chain reaction (MSP) methods. DNA samples were extracted, subjected to bisulfite conversion and then used for both the microarray and MSP methods. This study successfully identified differentially methylated CpGs (DMCs) as biomarker for each subtype classification of breast cancer: Luminal A (hypermethylation of ADAMTSL2 gene; cg14397888), Luminal B (hypomethylation of ADAMTSL2 gene; cg14397888), HER2+ (hypermethylation of PTPRN2 gene; cg25910261), and TNBC (hypomethylation of LCLAT1 gene; cg15652532). The DMC biomarker found for the HER2+ subtype, hypermethylation in the PTPRN2 gene (cg25910261), has the potential to be used by healthcare providers to identify HER2+ patients and provide the HER2-targeted therapy to improve the patient’s survival. In addition, our developed MSP method could produce an effective diagnostic tool for classifying the Luminal A and Luminal B subtypes, with accuracies of 75% and 76%, respectively.
Beetroot (Beta vulgaris) potential in preventing colorectal cancer using in-silico analysis Dwijayanti, Adisti; Azizah, Norma N.; Erlina, Linda; Kusmardi, Kusmardi; Ningsih, Sri S.; Fadilah, Fadilah; Hashim, Najihah M.
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1578

Abstract

Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide, necessitating the need for an effective therapeutic strategy. Beta vulgaris (beetroot) possesses active compounds that exert anti-cancer properties. The aim of this study was to evaluate the potential of beetroot as a preventative agent against the progression of CRC using differentially expressed gene (DEG) analysis and network pharmacology approaches. The protein-protein interaction network and molecular docking analyses were employed to assess the key interactions of beetroot active compounds with CRC-related target protein. Cytotoxicity of beetroot extract was experimentally evaluated using 3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl tetrazolium bromide (MTT) assay on the HT29 cell line. The result of this study showed that protein in the cell cycle was significantly enriched in CRC, with cyclin-dependent kinase 4 (CDK4) gene as one of the specific genes. Quercetin, galangin, hesperidin, farrerol, and betanin were the most typical compounds of beetroot based on the Comparative Toxicogenomics Database (CTD). Molecular docking studies revealed the strong binding affinity between quercetin (-7.04 kcal/mol) and bentanin (-8.11 kcal/mol) with CDK4. Beetroot demonstrated anticancer properties against the HT29 cell line with IC50 value of 39.03±1.4 µg/mL. In conclusion, the beetroot extract has inhibitory activity against HT29 cell line proliferation, highlighting its potential in preventing the development of CRC through the substantial suppression of gene expression within the cell cycle pathway.
Co-Authors A. Oktaviani, Wiwin Abd. Malik, Marwati Abd. Rasyid Syamsuri Abdelrazig, Omnia Amir Osman Abdurahman . Adeko, Uun Adisti Dwijayanti Adrianus Dedy, Adrianus afif, muhammad faris Afrilia, Dea Agus Budiman Ahyani, Dellisa Aji, Ilham Purnama Akkapin, Supaphorn Alaqsa, Tengku Reza Suka Aldjokdja, Retno Kartika Alindra, Afridha Laily Almardhiyah, Alaina aloysius mering Altof, Muhammad Sayid Amalia, Mutiah Amanda, Thasya Andara, Aulia Andi Nuddin Andiani Andiani, Andiani Andon Hestiantoro Andreani, Mesi Anggraini Silalahi, Tia Ani Retno Prijanti Anugrah, Bintang Melgian Apriani, Yosi Apriansah, Yoga Arbi, Arbi Ardila, Melati Arum, Shalma Lestari Aryo Tedjo Asri Indah Lestari Asri Melani, Firna Asri, Andi Astari, Syirli Aulia, Rifanda Ay Ly Margaret, Ay Ly Azhara Fetri Stevana Azizah, Norma N. Azizah, Wafiq Azizzah, Lailatul Azwar, Beni B, Mas’ud Bada, Wahdi Badriul Hegar Baehaqi Baidawi, Achmad Barli, Muhammad Badrun Bayu, Silvana Bomantara, M Alif Brata, Yat Rospia Budi Bayu, Budi Bayu Budi, Asep Burhanuddin Burhanuddin Cendani, Gabriella Regita Chaisa, Elvara Salsabilla Clara Riski Amanda Cristina, Artha Uli D, Muh. Taufieq Damayanti, Lidya Damayanti, Nurul Resty Damayanti, Si Luh Putu Daud, Ruslia Dedi Afandi Dewi, Audrey Vista Candra Diana Sunardi Diman, Tiara Dimas Seto Prasetyo Dina Purnama Sari Diniwati Mukhtar DK, Sonia Dwi Puji Hastuti Dwira, Surya Erlangga, Maulana Deni Erlina, Linda Fadhelina, Nishbah Fadilah Fajarido, Ariski Fajrin, Ajeng M. Farhan, Aulia Muhammad Farid, Muchammad Fathur Rohman, Fathur Febriana Catur Iswanti Febriana Khairunnisa, Nadia Fena Ulfa Aulia Feronika, Elma Mei Firdaus, Adika Agil Fitri Febianti, Fitri Fitri, Khadijah Kalva Habibah, Fiza Asri Fauziah Hamidah . Hanifah Oswari Harahap, Rizki Melinda Harimurti, Putri Saskia Hasan, Risma Hi Hashim, Najihah M. Hasibuan, Rabitah Hanum Hazizah, Hazizah Heni Tri Agline, Heni Tri Hestyn Amalia Hikmatullah, Hikmatullah Holilur Rahman Hulaela, Hulaela Husein, Mohammad Bustanol Ibrahim, Agung Biladin Ilham, Muthi Adnin Inayatulloh, Siti Indah Fajarwati, Indah Indi Dharmayanti Indri Rahmawati Insani, Fauzi Azhar Iswara, Raja AFW. Izmala, Athariah Jaelan Usman, Jaelan Jaka Wijaya Kusuma Juliana Juliana Juwita, Indah Ratna Kamilah, Balqis Ketut, I Bagiastra Kezia, Immanuelle Khatimah, Andi Ummul Kiagus Ahmad Roni KOMARIYAH KOMARIYAH Krisnawati, Anita Budi Kristatila, Kristatila Kukuh Eka Prasetya, Kukuh Eka Kusmardi Kusmardi Laego, Riyanti Lailatul Husna Laily Fitriani Mulyani, Laily Fitriani Langasa, Siti Aigina Lestari, Andes Linda Herlina Lindasari, Ewil Lumbessy, Salnida Yuniarti Lusiantari, Dinda M, Fitra Tunisyah M. Rafi Maharsi, Eri Dian Maknun, Hurin In Manteto, Tiara Mappasere, Fatmawati A. Mariam Mariam, Mariam Marlizen, Abdi Marulak Simarmata Maryam, Riskianti Astuti Maulana, Hamsah Maulida, Rosda Melani, Firna Asri Miftahul Jannah Minggu, Musdalifa Moh. Mudassir Ali Monica, Maria Diyan Muhamad Rizqy Fadhillah Muhammad Istan, Muhammad Muhammad Nasrudin Muhammad Zaki Munir, Sanihu MUSTOPA RAMDHON N. Nurjanah Naimah, Rifngatun Nasution, Abdul Gani Jamora Nata, Edwin Triadi NI LUH PUTU INDI DHARMAYANTI Ningsih, Arie Dwi Ningsih, Eka Ristia Ningtyas, Divanda Sekar Rahayu Noorwati Sutandyo Novesa Nurgirisia, Novesa Novi Yantih Novita Sari Nugraha, Muhammad Nuryansyah Nur Azizah Nurhakim, M. Syara Nurhanifah Nurhanifah Nurhayati S Nurjanah, Diana Nurul Gusti Khatimah Paerah, Andi Panjaitan, Ingrid Paramita, Rafika I. Paramita, Rafika Indah Ponco Birowo Priyanda R Purba, Hastuti Handayani S Purwamita Budiutami, Khoirunnisa Puspita E. Wuyung Puteri, Delita Mustika Putra, Reyza Fachrezy Putri Utami, Anggi Putri, Galuh Meita Rabbani, Muhammad Aqil Rabi’ah, Rabi’ah Raden Mohamad Herdian Bhakti Rahmania, Cici Aulia Rahmi Aulia, Rahmi Ramadhani, Tivany Ramanata Disurya, Ramanata Rambe, Riris Nurkholida Ratnayani Reflis, Reflis Reni Paramita Retno A. Werdhani Rikardo, Angga Risma Handayani, Risma Rizki Amalia Rizky Clarinta Putri rizky mirani desi pratama Rizky, Farrel Rochma Wati, Rygga Farira Rosa, Feby Lilia Rosdiana Rosdiana Rosida Rosida Rosyid, Arif Abdul Rudi Heryanto S., Nurhayati Sabrina, Annisa Safitri, Laili Safitri, Yunni Safka, Lutvi Nabilla Sahila, Kurnia Sahsun, Darmila Saleh, Zulkiffli saleh, zulkifli Salim, Nurmai Salma, Siti Nurul Sapi’i, Muhammad Saputra, Yogy Ardian Saputra, Yusuf Septelia I. Wanandi SEPTELIA INAWATI WANANDI Silalahi, Tia Anggraini SJATHA, FITHRIYAH Sofia Sofia, Sofia Sofiah Sofiah Sonar S. Panigoro Songidan, Junaidi Sri S. Ningsih, Sri S. Sudarmono, Pratiwi Pudjilestari Sufia Shalehah Sugito, Syailendra Karuna Suhariyati, Eli Sukisno Sukisno, Sukisno Sumarto, Sabaria Susanti, Helmi Susanti, Lis Susanto, Deny Suyono Suyono Syahira, Khadijah Khansa Syaputra, Ramadhan Syaufuri, Intan Lhotifah Syavicky, Ahmad Reihan Syech Idrus Taufik Nugroho Toaha, Sahabuddin Tuti Alawiyah Tutik Lestari Virizky, Fayzha Walid, Ahmad Wawaimuli Arozal Wibisana, I GNG. Wirayuda, Adnan Wusthoa, Jumratul Yaqin, Moh. Ainul Yonada, Fitria Yuli Budiningsih Yulia Rosa Saharman Yuni Indriyanti Yurniati, Yurniati YUSNITA YUSNITA Zahra, Annisa Zulfia Memi Mayasari