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Gunaidi, Farell Christian
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Journal : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

 1 
Hubungan HDL, LDL, Apo A, dan Apo B dengan Kejadian Penyakit Jantung Koroner Ruslim, Welly Hartono; Firmansyah, Yohanes; Santoso, Alexander Halim; Edwin Destra; Gunaidi, Farell Christian; Fajarivaldi, Kresna Bambang
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 5 No. 1 (2025): Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v5i1.5932

Abstract

Coronary heart disease (CHD) in the elderly represents the primary clinical manifestation of atherosclerosis and remains a leading cause of death and morbidity. This cross-sectional study aimed to evaluate the role of High-Density Lipoprotein (HDL), Low-Density Lipoprotein (LDL), Apolipoprotein-A (APO-A), and Apolipoprotein-B (APO-B) in the diagnosis and prevention of CHD among the elderly population. The results demonstrated that both APO-A and HDL were significantly negatively correlated with CHD (r = -0.336, p = 0.008; r = -0.274, p = 0.032), suggesting that higher levels of APO-A and HDL are associated with a lower risk of CHD. Conversely, APO-B and LDL showed a significant positive correlation with CHD (r = 0.411, p = 0.001; r = 0.358, p = 0.005), indicating that elevated levels of APO-B and LDL are linked to an increased risk of CHD. These findings highlight that measuring Apolipoprotein A and B levels may offer more valuable insights into atherosclerotic and cardiovascular risk assessment and may enhance the effectiveness of CHD prevention compared to traditional lipid profiles.
Co-Authors Abizar Rafi, Muhammad Adam Aditya Pratama Aditya, Vincent Alexandro, Cristian Alexin, Corry Calista Alifia, Khalisya Alifia, Tosya Putri Alvianto, Fidelia Alwini, Muhammad Rifat Umar Amanda, Shelma Tria Amertha, Anak Agung Ngurah Putrayoga Andersan, Jonathan Andria Priyana Anggraeni, Natasha Anthony, Louis Averina, Friliesa Averina, Frilliesa Aziel, Disya Gwyneth Bachri, Fiqi Afrizal Biromo, Anastasia Ratnawati Bustam, Steve Geraldo Cahyadi, Stanley Surya Charissa, Olivia Chian, Sung Christiana, Catherine Dava Pratama, Muhammad Kevin Destra, Edwin Dewanto, Naomi Esthernita F. Dewanto, Naomi Esthernita Fauzia Dewanto, Paulus Gegana Thery Dinali, Diana Drew, Clement Dwiana, Alya Dzakwan, Muhammad Fikri Edbert, Bruce Edbert, Juan Edwin Destra Enike, Syilvia Cendy Enike, Sylvia Cendy Ernawati Ernawati Ernawati Ernawati Evelyn Evelyn Evelyn Fadhila, Arni Ismi Fajarivaldi, Kresna Bambang Febriana, Nafrisca Febriastuti, Abebi Felicia, Ivana Fernando Nathaniel Frisca Frisca Frisca Geoffrey Christian Lo Ghina, Andini Goh, Daniel Gracieene Gracienne Gracienne Gracienne Hardjanto, Kevin Angga Hariesti, Ribka Anggeline Harsono, Axsel Hartono, Eric Hartono, Vincent Aditya Budi Haryanto, Ines Hawari, Irawati Hekmatyar, Haritsyah Hendrianto, Rafindra Raja Hendrianto, Rifandra Rifqi Adi Herdiman, Alicia Herdiman, Julia Irawaty Hawari Istikanto, Ferdian Harum Jap, Ayleen Nathalie Jeffrey Jeffrey Johan Johan Johan, Richver Framanto Joshua Kurniawan Kadang, Fidelis Samudra Kartolo, Marenra Shinery Kasvana Kasvana, Kasvana Khoto, Anthon Eka Prayoga Kosasih, Robert Kristianto, Angeline Florencia Grace Kurniawan, Junius Kusuma, Kanaya Fide Lo, Geoffrey Christian Lontoh, Susy Olivia Lucius, Steven Hizkia Lumintang, Valentino Gilbert Mahendri, Ryan Dafano Putra Mano S, Donatila Marcella, Agnes Martin, Alfianto Mashadi, Fladys Jashinta Mayvians, Tizander Moniaga, Catharina Sagita Monika, Sesilia Nathaniel, Fernando Nikita Noer Saelan Tadjudin Peter Ian Limas Pranata, Catherine Christiana Pratama, Muhammad Kevin Dava Prayogo Khoto, Anthon Eka Purnomo, Yonathan Adi Putra, Feri Yanto Putra, Heri Yanto Putra, Muhammad Dzakwan Dwi Putri, Tiara Aulia Raden Seliwat Agung Aditya Rafi, Muhammad Adam Abizar Rafif, Akhtar Nawfal Raharjo, Budiarjo Notonagoro Ramadhani, Kenzie Rafif Ranindita Maulya Ismah Amimah Rayhan, Naufal Riadi, Seravin Janet Rosadi Putra, Rosadi Ruslim, Daniel Ruslim, Welly Hartono S, Donatila Mano Santoso, Alexander Halim Sari, Triyana Satyanegara, William Gilbert Setia, Nicholas Setiawan, Fiona Valencia Shirly Gunawan Sidarta, Erick Sim, Alfred Sutrisno Singh, Arwinder Sitorus, Ribka Angeline Hariesti Siufui Hendrawan Soebrata, Linginda Soeltanong, Dianova Sugiarto, Hans Sugiharto, Hans Sukianto, Louise Audrey Sunjaya, Angela Felicia Sunjaya, Anthony Paulo Suros, Angel Sharon Susilo, Muhammad Farhan Pratama Susy Olivia Lontoh Sutedja, Gina Triana Syarifah, Andini Ghina Tambunan, Nicholas Albert Tan, Nikita Tan, Sukmawati Tansil Tantoso, Lidya Teguh, Stanislas Kotska Marvel Mayello Warsito, Jonathan Hadi Widjaja, Yoanita Wijaya, Bryan Anna Wijaya, Christian Wijaya, Dean Ascha Wijayadi, Linda Julianti Yohanes Firmansyah Yudhitiara, Novia Yulishaputra, Muhammad Daffa Alghifari Yunita, Fenny Zhalila, Zhillan