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All Journal International Journal of Electrical and Computer Engineering Torani Journal of Fisheries and Marine Science Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Journal of Biomedicine and Translational Research JURNAL IPTEKS PEMANFAATAN SUMBERDAYA PERIKANAN Biomedical Journal of Indonesia Sinkron : Jurnal dan Penelitian Teknik Informatika Medical Laboratory Technology Journal Pendas mahakam : jurnal pendidikan dan pembelajaran Sekolah Dasar JURNAL MUQODDIMAH : Jurnal Ilmu Sosial, Politik dan Hummaniora Jurnal Ilmiah Mahasiswa Kedokteran Medisia Jurnal Pendidikan Matematika (JUDIKA EDUCATION) Fair Value: Jurnal Ilmiah Akuntansi dan Keuangan JURNAL PENDIDIKAN TAMBUSAI SRIWIJAYA JOURNAL OF MEDICINE ACTIVE: Journal of Physical Education, Sport, Health and Recreation Jurnal Teknologi Terpadu Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Menssana Jurnal Mantik Riyadhoh : Jurnal Pendidikan Olahraga Scientia Psychiatrica Journal of SPORT (Sport, Physical Education, Organization, Recreation, and Training) REMIK : Riset dan E-Jurnal Manajemen Informatika Komputer Jurnal PORKES RESLAJ: RELIGION EDUCATION SOCIAL LAA ROIBA JOURNAL Sriwijaya Journal of Surgery Open Access Indonesia Journal of Social Sciences Sriwijaya Journal of Ophthalmology JURNAL PENDIDIKAN SAINS SOSIAL DAN AGAMA Eureka Herba Indonesia Jurnal Pengabdian Masyarakat: Humanity and Medicine PRAJA observer: Jurnal Penelitian Administrasi Publik Natural Sciences Engineering and Technology Journal Oikonomia: Jurnal Manajemen Open Access Indonesian Journal of Medical Reviews Indonesian Community Empowerment Journal Jurnal Abdimas Bina Bangsa Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Open Access Indonesia Journal of Social Sciences Arkus Jurnal Pengabdian Kepada Masyarakat Patikala International Journal of Research and Applied Technology (INJURATECH) Journal of Informatics and Communication Technology (JICT) Journal of Anesthesiology and Clinical Research Scriptura : Jurnal Ilmiah Sustainability Science and Resources Journal International of Lingua and Technology Indonesian Journal Computer Science (ijcs) Jurnal Muara Olahraga Jurnal Multidisiplin Sahombu Sinergi International Journal of Communication Sciences Technology and Society Perspectives (TACIT) Scientific Journal of Pediatrics Jurnal Spektrum Komunikasi Sriwijaya Journal of Radiology and Imaging Research Journal of Social Science Utilizing Technology Sriwijaya Journal of Internal Medicine Sriwijaya Journal of Obstetrics and Gynecology Sriwijaya Journal of Otorhinolaryngology Jurnal Pengabdian Sosial Informatics and Software Engineering (ISE) Jurnal Perikanan Terpadu Journal of Informatics and Communication Technology (JICT) Journal of Social Science Utilizing Technology Journal of Industrial Engineering Innovation Communica : Journal of Communication Bambu Laut: Jurnal Pengabdian Masyarakat
RACHMAT HIDAYAT
Department Of Medical Biology, Faculty Of Medicine, Universitas Sriwijaya, Palembang, Indonesia
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Regulation of Cell Cycle Rachmat Hidayat; Hayati, Lusia
Biomedical Journal of Indonesia Vol. 6 No. 3 (2020): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v6i3.236

Abstract

The cell cycle is a vital process in the life of every organism. Normally, the cell cycleresults in cell division. Cell division consists of 2 main processes, namely DNAreplication and chromosome division that has been duplicated into 2 daughter cells.Cyclin is expressed periodically so that the cyclin concentration varies at each phase ofthe cell cycle. Cdks are threonine or serine protein kinases which must bind to cyclinfor its activation. The concentration of Cdks is relatively constant during the cell cycle.Cyclin-dependent kinase inhibitor (CKI) is a protein that can inhibit Cdk activity bybinding to Cdk or the cyclin-Cdk complex
Molahidatidosa from Pathophysiology to Clinical: Literature Review Hidayat, Rachmat; Irawan Sastradinata
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.260

Abstract

A B S T R A C THydatidiform is a gestational trophoblast disease which is histopathologicallycharacterized by the proliferation of avascular trophoblast cells and corial villi andundergoing hydrophic degeneration. The proliferation of trophoblast cells inhydatidiform moles can be in the form of cytotrophoblast, syncytiotrophoblast orintermediate trophoblast proliferation.
Sarcopenia from Pathophysiology to Clinical : Literature Review Hidayat, Rachmat; Nur Riviati
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.261

Abstract

A B S T R A C TThe causes of sarcopenia are thought to be multifactorial including: environmentalfactors, illness, activation of inflammatory pathways, mitochondrial dysfunction, lossof neuromuscular junctions, reduced number of satellite cells and changes in thequality of hormonal function. The mechanism of sarcopenia occurs because the agingprocess coupled with reduced physical activity can cause the formation of cytokinesto increase so that inflammation is easy, insulin resistant, anabolic resistance andneuromuscular impairments.
Omega-3 as an Anti-Inflammatory Modality: Literature Review Hidayat, Rachmat; Nur Riviati
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.262

Abstract

A B S T R A C TOmega-3 fatty acids are polyunsaturated fatty acids that have multiple double bonds,the first double bond is located on the third carbon atom of the omega-methyl group,the next double bond is located at the third carbon atom from the previous doublebond. The methyl omega group is the last group in the fatty acid chain. Omega-3 fattyacids are nutrients that play a vital role in the growth and development process ofbrain neuron cells for the intelligence of the born baby.
Bioethical Principles of Use of Experimental Animals in Biomedical Research Hidayat, Rachmat; Patricia Wulandari
Biomedical Journal of Indonesia Vol. 7 No. 1 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i1.267

Abstract

A B S T R A C TResearch is an activity carried out based on scientific principles and methodssystematically to obtain information, data, and information from related subjects, withunderstanding the theory and proving assumptions and / or hypotheses. The resultsobtained are conclusions that can be applied or become additional knowledge for theadvancement of science. However, research activities must still respect the rights anddignity of research subjects. Health research includes biomedical, epidemiological,social, and behavioral research. Some health research can be done in vitro, usingmathematical models, or computer simulations.
Anatomy and Physiology of Animal Model Rats in Biomedical Research Hidayat, Rachmat; Patricia Wulandari
Biomedical Journal of Indonesia Vol. 7 No. 2 (2021): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/bji.v7i2.287

Abstract

A distinguishing feature of rodents, including rats, is the absence of canines and thepresence of prominent incisors. Rats are monophydontic, meaning they grow one setof teeth in their lifetime. The enamel of the rodent incisor contains iron, which givesit its yellow-orange color. Rats are mammals and as such, possess many similaritieswith other mammals. Only the peculiarities of the rat’s anatomy are addressed. Malerats reach puberty at 40 - 60 days of age. Descent of the testes usually occursbetween days 30 - 60. Sperm counts vary by strain. The male rat has an os penis.Male rats have the following accessory sexual organs: ampulla, seminal vesicles,prostate, bulbourethral glands, coagulating glands, and preputial glands. Thecoagulating gland and prostatic and vesicular secretions are responsible for thecopulation plug, a firm plug deposited in the vagina of the female after copulation.(This plug, when found outside the female rat, is capsuleshaped and approximately5 mm long.) The male rat has no nipples. The adult male rat has a prominentscrotum and a longer anogenital distance than the female rat.
mRNA NFATC1 Expression in Genu Osteoarthritis with Effusion Muhammad Reagan; Hermansyah; Rachmat Hidayat; Surya Darma; Putri Muthia
Biomedical Journal of Indonesia Vol. 6 No. 2 (2020): Biomedical Journal of Indonesia
Publisher : Fakultas Kedokteran Universitas Sriwijaya (Faculty of Medicine, Universitas Sriwijaya) Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Based on a study conducted by the WHO Global Burden of Disease in 2010 stated, OA ranks11th, the cause of disability in the world, and ranks 6th in East Asia and the Asia-Pacificcountries, ranked 10th in North America, ranked 7th in Eastern Europe , and ranked 13th inWestern Europe. Pathogenesis of osteoarthritis (OA) as degenerative joint disease that was oncethought caused by a mechanical process. The prevalence, etiology, pathogenesis and progressionof OA are still not understood until now, mainly because of the many influencing factors. Thistype of research is a analytic study. It was conducted in Rheumatology Polyclinic Dr.Mohammad Hoesin Palembang from February to December 2019. Affordable researchpopulation is all genu osteoarthritis sufferers with effusion who go to Dr. RSUP MohammadHoesin Palembang as 80 samples. Comparison of NFATC1 mRNA levels in genu osteoarthritispatients with effusion shows that there is no difference in gender and history of diabetes, whereashypertension history and degree of osteoarthritis based on Lawrence Kalgren shows significantlydifferent expression of NFATC1 mRNA. Age with NFATC1 mRNA expression showed nosignificant correlation, in contrast to BMI, Stroke Test and joint effusion volume showed a weaksignificant correlation, even though the direction of the correlation was negative on Stroke Testand joint effusion volume.
The Importance of Inventory Management in Pharmaceutical Practice Rachmat Hidayat; Irsan Saleh
Open Access Indonesia Journal of Social Sciences Vol. 3 No. 1 (2020): Open Access Indonesia Journal of Social Sciences
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.154 KB) | DOI: 10.37275/oaijss.v3i1.22

Abstract

Efficient inventory management enhances gross profits and net profits by reducing the cost of procured pharmaceutical products and associated operational expenses. In addition, cash flow will improve upon saving on purchasing and storing less costly products. Such cash flow can be used to pay operational expenses and invest in other services. In addition to the negative impacts on financial outcomes from the pharmacy’s business perspective, inventory mismanagement could have deleterious corollaries on patient safety. Such outcomes can be attributed by the availability of expired, counterfeit, substandard, or spoiled products; unavailability of essential products; unclaimed prescriptions; and not updating formularies. From both financial and operational perspectives, efficient inventory management plays a great role in pharmacy practice. Thus, both methods of inventory management & methods of evaluating inventory management should be integrated into the curriculum of pharmacy programs, in addition to including them in the continuing education courses for registered pharmacists.
What is Urgency of Health-Seeking Behaviour Concept in Health Policy? Rachmat Hidayat; Patricia Wulandari
Open Access Indonesia Journal of Social Sciences Vol. 3 No. 1 (2020): Open Access Indonesia Journal of Social Sciences
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (257.204 KB) | DOI: 10.37275/oaijss.v3i1.23

Abstract

Health-seeking behavior (HSB) is a concept that requires contributions from multidisciplinary sciences, namely health, psychology, and social sciences. Understanding the HSB concept helps academics and practitioners to understand the individual's reasons for seeking medical help. Health service facility factors are generally often blamed for the low quality of health in a place for example, the low quality of health in the village is often associated with the limitations of health facilities in the village compared to in the city. It turns out that not all of them and not the majority of the low quality of health in an area is only due to the limitations of health facilities, sometimes it can be caused by the values held by the local community.
Peroxisome Proliferator Activator Receptor (PPAR) γ Agonis Menurunkan Kadar Sitokin Anti Inflamasi TGF-β dan IL-10 pada Tikus Putih Wistar Model Inflamasi Vaskular Rachmat Hidayat
JURNAL KEDOKTERAN DAN KESEHATAN Vol 2, No 3 (2015)
Publisher : Fakultas Kedokteran Universitas Sriwijaya

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Abstract

Inflamasi vaskular merupakan kondisi patologis yang mendasari terjadinya gangguan pada pembuluh darah. NADPH oksidase merupakan enzim sentral yang mengaktivasi kaskade inflamasi sehingga dihasilkan  superoxide (Reactive Oxygen Species), aktivasi sel fagosit, pengeluaran sitokin proinflamasi dan kerusakan jaringan vaskular. Aktivasi PPAR γ akan menginhibisi faktor transkripsi NF-κB dan  menurunkan ekspresi gen sitokin proinflamasi. Pioglitazon dan telmisartan berkerja  sebagai full dan partial agonis PPAR-γ. Diharapkan kedua agen ini dapat berperan dalam mencegah inflamasi vaskular dengan aktivasi PPAR γ. Tikus Wistar jantan usia 10 minggu (n= 30) dilakukan randomisasi ke dalam enam  kelompok, 5 ekor tikus tiap kelompok, perlakuan selama 8 minggu. Kelompok 1 :kontrol negatif. Kelompok 2 : diberi NaCl 8%  dan aquades 5 ml. Kelompok 3 dan 4 :  diberi NaCl 8% serta pioglitazon secara berurutan dengan dosis 3 mg/kgBB dan 6 mg/kgBB. Kelompok 5 dan 6 : diberi NaCl 8% serta telmisartan secara berurutan dengan dosis 6 mg/kgBB dan 12 mg/kgBB. Kadar TGF-β dan IL-10 dianalisis dengan ELISA. Uji ANOVA dilanjutkan dengan pos hoc test (Boferroni test) digunakan untuk menganalisis variabel. Kadar TGF β1 dan IL-10  kelompok 3-6 menunjukkan penurunan signifikan dibandingkan  kelompok  2. Telmisartan dan pioglitazon  menurunkan kadar TGF-β1 dan IL-10 pada jaringan aorta tikus putih seiring peningkatan dosis.
Co-Authors Abdul Mahatir Najar Abdulwahab Hakimi Abu Bakar Abu Bakar Abudarda, Andi Risda Fitrianti Adnindya, Msy Rulan Agus Indra Jaya Agustian, Kresnawidiansyah Ahadi Aulia Rahman Ahmad Ahmad Ahmad Fatoni Ahmad Salim, Ahmad Ahmad, Arfandi Aji, Muhammad Pramono Alif Tunru, Andi Alvian, M. Andri Anang Tribowo Andres Andres Andriana, Nadila Andronias Siregar Annisa Wimaulia Azlin Anuar, Arman Bin Apriwandi . Arifin, Nurdin Arindi Maretzka Ayeshah A Rosdah Azakhia, Yolanda Citra Baharuddin Baharuddin Bella Stevanny Bemba, Tonia Buchari Buchari Budi Pratiti Carla R Marchira Catherine Christine, Debbie Cinthya Callathea Dariyanto, Erwin Debby Handayanti Harahap Dessa, Rima Djoko Widodo Edith Humries Ella Amalia, Ella Ellya Verawati Elsa Iskandar Erizka Rivani Erma Agusliani Ester G Pansserga Fahcreza Faisal Syahputra, Faisal Fathonah, Andina Nur Fatmawati Fatmawati Fatmawati Fildzah Hashifah Taufiq Fiona Widyasari Griselda Griselda Hadi, Dudi Abdul hadi, marwan Handayani, Lisa Hani Subakti Haryanto Haryanto Herman Paninggiran Hermansyah Hermansyah Hermansyah Herry Hasnawi HUSNUL KHOTIMAH Ichsan, Amirul Ika Kartika Ikrima Ikrima Ilahi, Rahmat Imam Pribadi Inggarsih, Rara Irawan Sastradinata Irawan Sastradinata Irham Irham Irsan Saleh Ismar Hamid Iwan Setiawan Jamalullail Jayawarsa, A.A. Ketut Joko Marwoto Joko Marwoto Joko Marwoto Junoretta Haviva Ernanto Kashardi, Kashardi Kemas Abdul Mutholib Luthfi Kemas Ya'kub Rahadiyanto Krishna, Hidan Bayu Krisna Murti Kumba Digdowiseiso, Kumba KURNIA KURNIA, KURNIA Lestari Barus, Irene Sukma Linda Purnama Listianingsih, Lona Lusia Hayati Lusia Hayati Lusia Hayati Lusia Hayati, Lusia Luthfi, Kemas Abdul Mutholib Mail, Abdul Maisya, Irin Makbruri Amin Malik, Aulia Januar Maria Margareth Wilson Marlinda, Dwi MARYANTI, LILIS Maximillian Wilson Meilinda, Salsa Rizkia Mgs Irsan Saleh Mgs Irsan Saleh Mirna Dianita Muallin, Muallin Mubarok, E. Saefuddin Muhammad Anzarach Pratama Muhammad Bima Muhammad Irsan Saleh Muhammad Reagan Muhammad Reagen Muhammad Rizky Hidayatullah Muhlis Muhlis Mukti Zainuddin Muslina Muslina Muthia, Putri Muthia, Putri Nadia Khoirina Najla Khairunnisa Nasriandi Nasriandi Ninuk Riesmiyantiningtias Nita Parisa Noviyan, Rizky Dwi Nur Ainun Nur Riviati, Nur Nur, Suaib Nurhasanah Nurhayati, M Sinta nurliah, nurliah Nurrahmah, Andi Oktaviyani, Hikmatul Olivia Azalia Putri Pamungkas, K J paosan, ahmad Patricia Wulandari Patry, Him Petty Purwanita pongtiku, ita Pramono, Yacob Agung Prayudhi, Risa Prihatina Anjela Purnamasari, Septi Puspa Sari, Puspa Puspa Zulaika Puspitasari, Andini Putra, Suadi Sapta Putri Muthia Rachman, Andry Arifian Raden Ayu Adelia Safitri Raden Sunita Radiyati Umi Partan Radjikan Rahayu, Rosi Rahman, Ahadi Aulia Rahman, Ahadi Aulia Rahmat Saleh Raihan Aqiilah N.L. , Andi Ahmad Ramadhan, Hamzah Ramli, Musdalifah Rara Inggarsih Rashidah Unaib Al Zayid Rasyidah Jalil Reisha Notonegoro Resva Meinisasti Rety, Alghazali Riani Erna Rijaluddin, Khalid Rima Rachmawati Riri Juliantika Riswanto, A Heri Riswanto, A. Heri Riswanto, Andi Heri Riswanto, Heri Rosiyadi, Didi Safruddin Sahidan Sahidan Sahidan Sahidan Salni Salni Saman, Saman Samsuri, Fhadil Hidayat Sapinah, Pipin Sarah Sari, Anggi Psutpita Sari, Windy Dian Sarnato, Ahmad Zain Satriansyah , Arief Sekarini, Ratih Ayu Sepang, Rosa Marten Septi Purnamasari Septi Purnamasari Shalita Dastamuar Shina Abdulkadir Sony Sanjaya Sonya Syarifah Sri Nita Sri Nita Sri Nita Sri Nita, Sri Sri Tuti Rahmawati Sri Vandayuli Riorini St. Aisjah Farhum, St. Aisjah Sudaramanto, Bagus Sujud, Atsari Surya Darma Surya Darma Syarif Burhan, Ahmad Tanjung, Enha Syahrul Taufiq Indera Jayadi Tiara Fatrin Triwani Triwani Tungki Pratama Umar Tungki Pratama Umar Tunru, Andi Alif Udi Rusadi Uswatun Hasanah Veithzal Rivai Zainal Wardani, M. Fikri Wardiansyah Wiganepdo, Suryatno Wijaya, Maya Septa Winda Ramadianti, Winda Wirna, Risalah Sabila Yeni Agustin Yundari, Yundari Yuni sahruni, Ade Yusnaini Zen, Agustian Ziske Maritska