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All Journal Jurnal Pendidikan dan Pembelajaran Khatulistiwa (JPPK) Seminar Nasional Teknik Kimia Kejuangan Fakultas Ekonomi PUJANGGA: Jurnal Bahasa dan Sastra PROSIDING SENATEK FAKULTAS TEKNIK UMP Jurnal Ampere Jurnal Manajemen Pelayanan Publik Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) JPM (Jurnal Pemberdayaan Masyarakat) JURNAL PENDIDIKAN TAMBUSAI AL-HAYAT: Journal of Biology and Applied Biology Jurnal Literasiologi Eksakta : Berkala Ilmiah Bidang MIPA PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JURNAL SURYA ENERGY Jurnal Pendidikan Teknologi Pertanian Transformasi : Jurnal Pendidikan Matematika dan Matematika Babali Nursing Research INCARE Akrab Juara : Jurnal Ilmu-ilmu Sosial STUDI PELAKSANAAN SELFMEDICATION PADA PENDERITA DIARE BERDASARKAN TINGKAT PENGETAHUAN MASYARAKAT PESISIR KECAMATAN SOROPIA KABUPATEN KONAWE Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) Community Empowerment Jurnal Nuansa Akademik: Jurnal Pembangunan Masyarakat Devotion: Journal of Research and Community Service Narra J Jurnal Media Informatika Jurnal Pengabdian Masyarakat (ABDIRA) Jurnal Abdimas Ekonomi dan Bisnis Jurnal Abdimas Komunikasi dan Bahasa BIOCHEPHY: Journal of Science Education Al-Idzaah : Jurnal Dakwah dan Komunikasi AKM: Aksi Kepada Masyarakat J-KIP (Jurnal Keguruan dan Ilmu Pendidikan) Jurnal Ilmiah Arsitektur Jurnal Teknik Elektro Eduthink: Jurnal Pemikiran Pendidikan Islam COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Jurnal PRIMED:Primary Education Journal atau Jurnal Ke-SD An Jurnal Sains dan Teknologi Journal Evidence Of Law Seulanga : Jurnal Pendidikan Anak Makara Journal of Science Tsaqofah: Jurnal Penelitian Guru Indonesia YASIN: Jurnal Pendidikan dan Sosial Budaya Indonesian Journal of Medical Chemistry and Bioinformatics Jurnal Penelitian Ilmu Pendidikan Indonesia Jurnal Ruaya : Jurnal Penelitian dan Kajian Ilmu Perikanan dan Kelautan Mestaka: Jurnal Pengabdian Kepada Masyarakat Eduvest - Journal of Universal Studies Innovative: Journal Of Social Science Research Jurnal Pengabdian Masyarakat Bangsa Jurnal Pengabdian Inovasi Masyarakat Indonesia International Journal of Trends in Accounting Research Media Akuntansi Perpajakan Waluya The International Science of Health Journal Cendikia Pendidikan GEMBIRA (Pengabdian Kepada Masyarakat) TACET Jurnal Pendidikan dan Kajian Seni Indonesian Journal of Community Empowerment Ta'dibiya: Jurnal Agama dan Pendidikan Islam Jurnal Imiah Pengabdian Pada Masyarakat (JIPM) Indonesian Journal of Biomedicine and Clinical Sciences Journal of Social Work and Science Education Tadibiya; Jurnal Agama dan Pendidikan Islam Journal of Islamic Elementary Education Indonesian Journal of Jamu Aspirasi: Jurnal Ilmiah Administrasi Negara Jurnal Surya Energy Zad Al-Ummah: Jurnal Pengabdian Masyarakat
Fadilah Fadilah, Fadilah
Jurusan Teknik Kimia, Fakultas Teknik, Universitas Sebelas Maret Jl. Ir. H. Sutami Surakarta, 57126
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Word Formation in Tempo English Articles Following the Indonesian Military Law Amendments Passing fadilah, fadilah; Yuni Indriyanti
Pujangga Vol. 11 No. 2 (2025): Volume 11 Nomor 2 Tahun 2025
Publisher : Universitas Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47313/pujangga.v11i2.4330

Abstract

This study aims to analyze the types and frequency of word formation processes found in Tempo’s national English articles following the passing of the Indonesian Military Law amendments. This research employs a descriptive qualitative method using George Yule’s (2023) theory of word formation as the main framework. The data consist of five online national news articles published by Tempo between March 20th and March 27th, 2025. The analysis reveals that six types of word formation processes appear in the articles, namely borrowing, derivation, multiple processes, compounding, conversion, and initialism. Borrowing is found to be the most dominant type with 11 data, followed by 7 data as derivation, 3 data as multiple processes, 2 data as compounding, 2 data as conversion, and 1 data as initialism. The findings show that borrowing plays a significant role as the most productive word formation process in the articles, indicating that many English words used in news media come from other languages. Moreover, the study highlights that not all word formation types consistently appear, and a few words could not be categorized into any existing morphological process. These findings underline the importance of borrowing in shaping the English vocabulary in Indonesian journalistic contexts.
Prediction of Active Compounds From Annona Muricata Leaves As Inhibitors of the Wdr5–Myc Interaction in Breast Cancer Through A Molecular Docking Approach Tedjo, Aryo; Yantih, Novi; Fadilah, Fadilah; Rafi, Mohamad
Devotion : Journal of Research and Community Service Vol. 7 No. 1 (2026): Devotion: Journal of Community Research
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/devotion.v7i1.25607

Abstract

Breast cancer is one of the malignancies with a high morbidity rate, in which the excessive activation of the Myc proto-oncogene protein (MYC) plays a critical role in tumor proliferation and progression. MYC requires the presence of WD repeat-containing protein 5 (WDR5) to bind to its target genes; thus, the WDR5–MYC interaction represents a strategic target for the development of breast cancer therapy. This study aimed to identify leaf metabolites of Annona muricata with the potential to inhibit the WDR5–MYC interaction using an in silico approach. A total of 193 metabolites from the KNApSAcK database were modeled in 3D and analyzed by molecular docking using Molegro Virtual Docker (MVD) against the structure of WDR5 in complex with a MYC inhibitor fragment (PDB ID: 6UHY). Docking validation was performed by redocking the native ligand, 1-cyclohexyl-1H-benzimidazole-5-carboxylic acid, which yielded an RMSD value < 2 Å. The docking results indicated that epicatechin gallate, muricatetrocin B, and isoorientin exhibited the highest binding affinities, with Moldock Scores of –123.522, –115.862, and –97.3305 kJ/mol, respectively, supported by strong hydrogen-bond interactions. Interaction visualization revealed that epicatechin gallate formed more key interactions with critical residues in the WDR5 active site compared with the native ligand. These findings suggest that epicatechin gallate is a promising candidate for inhibiting the WDR5–MYC interaction and may be further developed as a natural-product-based anticancer agent.
Doxycycline Suppresses Hypertension through Renin– Angiotensin System (RAS) Regulation: Insights from Molecular Docking and Renal Gene Expression Fajarido, Ariski; Fadilah, Fadilah; Arozal, Wawaimuli; Fatriansyah, Jaka Fajar; Pradana, Agrin Febrian; Monayo, Edwina Rugayah
Molecular and Cellular Biomedical Sciences Vol 10, No 1 (2026)
Publisher : Molecular and Cellular Biomedical Sciences

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v10i1.744

Abstract

Background: Doxycycline, a tetracycline antibiotic known for inhibiting matrix metalloproteinases, has shown potential antihypertensive effects. However, its role in modulating the renin–angiotensin system remains poorly understood. This study aims to specifically evaluate Doxycycline’s effects on key RAS components and blood pressure responses to clarify its underlying mechanism and support its development as a targeted antihypertensive therapeutic candidate.Materials and Methods: This study integrated an in-silico and experimental approach to assess the antihypertensive effects of doxycycline. Bioinformatics analyses were first conducted, including target prediction, gene ontology enrichment, hub-gene identification, PPI network construction, and KEGG pathway analysis, followed by molecular docking and molecular dynamics simulations to predict doxycycline’s interactions with key RAS targets. To validate these computational findings, qRT-PCR was performed to measure the expression of selected genes in kidney tissues from hypertensive rats.Results: Bioinformatics analysis identified six key target genes, including AGT, AGTR1, AGTR2, REN, ACE, and ACE2. Molecular docking showed that doxycycline exhibited stronger binding affinity to AGTR1 (-8.346 kcal/mol) than its native ligand. Molecular dynamics confirmed the stability of the doxycycline–AGTR1 complex at 20 ns. Gene expression analysis of kidney tissues from hypertensive rats revealed a significant reduction in AGTR1 expression in the group treated with doxycycline 15 mg/kg (p<0.05), while no significant change was observed at 30 mg/kg.Conclusion: Low-dose doxycycline may modulate the renin–angiotensin pathway through AGTR1 inhibition, indicating its potential as a candidate for further antihypertensive research and warranting more comprehensive in vivo evaluation.Keywords: Hypertension, doxycycline, molecular docking, gene expression, Renin-Angiotensin System
Penerapan Teknologi Silase dan Fermentasi untuk Ketahanan Pakan Ternak di Daerah Sub-optimal Rejosari - Bantul Susanti, Ari Diana; Cahyadi, Muhammad; Paryanto, Paryanto; Fadilah, Fadilah
Jurnal Pemberdayaan Masyarakat Vol 6 No 1 (2021): Mei
Publisher : Direktorat Penelitian dan Pengabdian kepada Masyarakat (DPPM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21067/jpm.v6i1.4983

Abstract

The availability of ruminant feed in terms of amount and nutritional adequacy is a common problem during the dry season. This condition is worst at the peak of the dry season (July - October) such as that faced by the Kelompok Tani Rukun Binantu of Rejosari in Bantul Regency - Yogyakarta. Pre-survey shows that the cost of feed in the dry season is uncompetitive to the price of cattle. This problem was solved by Program Kemitraan Masyarakat (PKM – UNS) 2020 with workshop in cattle feed preservation using silage and fermentation techniques. The silage technique is used in conventional-local forage, while the fermentation technique is aimed at preserving low-nutrient animal feed as well as improving digestibility and nutritional adequacy of the feed. Product’s monitoring and evaluation are carried out after 7 days for fermentation technique and 21 days for silage technique. The program is success in solving of Mitra’s problems and it is also one of Tri Dharma Perguruan Tinggi in technology transfer for rural communities.
Implementasi Model Predictive Control (MPC) pada sistem HVAC Skala Kecil untuk Optimasi Kinerja Termal dan Efisiensi Energi Fadilah, Fadilah; Zulkiffli Saleh; Hafiidh Muzaki; Asri Indah Lestari; Yosi Apriani
Jurnal Surya Energy Vol. 10 No. 2 (2026)
Publisher : Teknik Elektro, Universitas Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/jse.v10i2.1691

Abstract

Sistem Heating, Ventilation, dan Air Conditioning (HVAC) merupakan salah satu penyumbang konsumsi energi terbesar pada bangunan, sehingga diperlukan strategi kendali yang tidak hanya mampu menjaga kenyamanan termal tetapi juga meningkatkan efisiensi energi. Metode kendali konvensional PID memiliki keterbatasan dalam menangani kendala system dan perubahan kondisi lingkungan. Oleh karena itu, penelitian ini mengkaji implementasi Model Predictive Control (MPC) pada subsistem Air Conditioner (AC) pada HVAC skala kecil untuk mengoptimalkan kinerja termal dan konsumsi energi. Sistem HVAC dimodelkan sebagai sistem termal satu zona menggunakan pendekatan lumped parameter dan direpresentasikan dalam bentuk model state-space diskrit. MPC dirancang dengan fungsi objektif yang meminimalkan kesalahan pelacakan suhu terhadap setpoint dan perubahan daya pendinginan dengan memeprtimbangkan kendala operasional system. Pengujian dilakukan melalui simulasi menggunakan MATLAB dengan skenario pelacakan setpoint suhu dan gangguan lingkungan. Kinerja MPC dibandingkan dengan kendali PID konvensional berdasarkan respon suhu dan konsumsi energi. Hasil simulasi menunjukkan bahwa MPC mampu menghasilkan respons suhu yang stabil dengan konsumsi energi yang lebih rendah dibandingkan kendali PID. Secara kuantitatif, MPC membutuhkan energi sekitas 56,6 Wh, lebih rendah dibanding PID sebesar 58,5 Wh. Meskipun demikian, MPC memiliki waktu tunak yang sedikit lebih lama, yaitu sekitar 8 menit, dibandingkan dengan 6 menit pada kendali PID. Selain itu, MPC menghasilkan aksi kendali yang lebih halus, yang terlihat dari perubahan daya pendinginan yang lebih terkendali. Hasil ini menunjukkan bahwa MPC efektif sebagai alternatif kendali untuk meningkatkan kenyamanan termal dan efisiensi energi pada system HVAC skala kecil.
Co-Authors A. Oktaviani, Wiwin Abd. Malik, Marwati Abd. Rasyid Syamsuri Abdelrazig, Omnia Amir Osman Abdurahman . Adeko, Uun Adisti Dwijayanti Adrianus Dedy, Adrianus afif, muhammad faris Afrilia, Dea Agus Budiman Ahyani, Dellisa Aji, Ilham Purnama Akkapin, Supaphorn Alaqsa, Tengku Reza Suka Aldjokdja, Retno Kartika Alindra, Afridha Laily Almardhiyah, Alaina aloysius mering Altof, Muhammad Sayid Amalia, Mutiah Amanda, Thasya Andara, Aulia Andi Nuddin Andiani Andiani, Andiani Andon Hestiantoro Andreani, Mesi Anggraini Silalahi, Tia Ani Retno Prijanti Anugrah, Bintang Melgian Apriani, Yosi Apriansah, Yoga Arbi, Arbi Ardila, Melati Ari Diana Susanti, Ari Diana Arum, Shalma Lestari Aryo Tedjo Asri Indah Lestari Asri Indah Lestari Asri Melani, Firna Asri, Andi Astari, Syirli Aulia, Rifanda Azhara Fetri Stevana Azizah, Norma N. Azizah, Wafiq Azizzah, Lailatul Azwar, Beni B, Mas’ud Bada, Wahdi Badriul Hegar Baehaqi Baidawi, Achmad Barli, Muhammad Badrun Bayu, Silvana Bomantara, M Alif Brata, Yat Rospia Budi Bayu, Budi Bayu Budi, Asep Burhanuddin Burhanuddin Cahyadi, Muhammad Cendani, Gabriella Regita Chaisa, Elvara Salsabilla Clara Riski Amanda Cristina, Artha Uli D, Muh. Taufieq Damayanti, Lidya Damayanti, Nurul Resty Damayanti, Si Luh Putu Daud, Ruslia Dedi Afandi Dewi, Audrey Vista Candra Diana Sunardi Diman, Tiara Dimas Seto Prasetyo Dina Purnama Sari Diniwati Mukhtar DK, Sonia Dwi Puji Hastuti Erlangga, Maulana Deni Erlina, Linda Fadhelina, Nishbah Fadilah Fajarido, Ariski Fajrin, Ajeng M. Farhan, Aulia Muhammad Fathur Rohman, Fathur Fatriansyah, Jaka Fajar Febriana Catur Iswanti Febriana Khairunnisa, Nadia Fena Ulfa Aulia Feronika, Elma Mei Firdaus, Adika Agil Fitri Febianti, Fitri Fitri, Khadijah Kalva Habibah, Fiza Asri Fauziah Hafiidh Muzaki Hamidah . Hanifah Oswari Harahap, Rizki Melinda Harimurti, Putri Saskia Hasan, Risma Hi Hashim, Najihah M. Hasibuan, Rabitah Hanum Hazizah, Hazizah Heni Tri Agline, Heni Tri Hestyn Amalia Hikmatullah, Hikmatullah Holilur Rahman Hulaela, Hulaela Husein, Mohammad Bustanol Ibrahim, Agung Biladin Ilham, Muthi Adnin Inayatulloh, Siti Indah Fajarwati, Indah Indi Dharmayanti Indri Rahmawati Insani, Fauzi Azhar Iswara, Raja AFW. Izmala, Athariah Jaelan Usman, Jaelan Jaka Wijaya Kusuma Juliana Juliana Juwita, Indah Ratna Kamilah, Balqis Ketut, I Bagiastra Kezia, Immanuelle Khatimah, Andi Ummul Kiagus Ahmad Roni KOMARIYAH KOMARIYAH Krisnawati, Anita Budi Kristatila, Kristatila Kukuh Eka Prasetya, Kukuh Eka Kusmardi Kusmardi Laego, Riyanti Lailatul Husna Laily Fitriani Mulyani, Laily Fitriani Langasa, Siti Aigina Lestari, Andes Linda Herlina Lindasari, Ewil Lumbessy, Salnida Yuniarti Lusiantari, Dinda M, Fitra Tunisyah M. Rafi Maharsi, Eri Dian Maknun, Hurin In Manteto, Tiara Mappasere, Fatmawati A. Mariam Mariam, Mariam Marlizen, Abdi Maryam, Riskianti Astuti Maulana, Hamsah Maulida, Rosda Melani, Firna Asri Miftahul Jannah Minggu, Musdalifa Moh. Mudassir Ali Monayo, Edwina Rugayah Monica, Maria Diyan Muhamad Rizqy Fadhillah Muhammad Istan, Muhammad Muhammad Nasrudin Muhammad Zaki Munir, Sanihu MUSTOPA RAMDHON N. Nurjanah Naimah, Rifngatun Nasution, Abdul Gani Jamora Nata, Edwin Triadi NI LUH PUTU INDI DHARMAYANTI Ningsih, Arie Dwi Ningsih, Eka Ristia Ningtyas, Divanda Sekar Rahayu Noorwati Sutandyo Novesa Nurgirisia, Novesa Novi Yantih Novita Sari Nugraha, Muhammad Nuryansyah Nur Azizah Nurhakim, M. Syara Nurhanifah Nurhanifah Nurhayati S Nurjanah, Diana Nurul Gusti Khatimah Paerah, Andi Panjaitan, Ingrid Paramita, Rafika I. Paramita, Rafika Indah Paryanto Ponco Birowo Pradana, Agrin Febrian Priyanda R Purba, Hastuti Handayani S Purwamita Budiutami, Khoirunnisa Puspita E. Wuyung Puteri, Delita Mustika Putra, Reyza Fachrezy Putri Utami, Anggi Putri, Galuh Meita Rabbani, Muhammad Aqil Rabi’ah, Rabi’ah Raden Mohamad Herdian Bhakti Rahmania, Cici Aulia Rahmi Aulia, Rahmi Ramadhani, Tivany Ramanata Disurya, Ramanata Rambe, Riris Nurkholida Ratnayani Reflis, Reflis Reni Paramita Retno A. Werdhani Rikardo, Angga Risma Handayani, Risma Rizki Amalia Rizky Clarinta Putri rizky mirani desi pratama Rizky, Farrel Rochma Wati, Rygga Farira Rosa, Feby Lilia Rosdiana Rosdiana Rosida Rosida Rosyid, Arif Abdul Rudi Heryanto S., Nurhayati Sabrina, Annisa Safitri, Laili Safitri, Yunni Safka, Lutvi Nabilla Sahila, Kurnia Sahsun, Darmila Saleh, Zulkiffli saleh, zulkifli Salim, Nurmai Salma, Siti Nurul Sapi’i, Muhammad Saputra, Yogy Ardian Saputra, Yusuf Septelia I. Wanandi Silalahi, Tia Anggraini SJATHA, FITHRIYAH Sofia Sofia, Sofia Sofiah Sofiah Sonar S. Panigoro Songidan, Junaidi Sri S. Ningsih, Sri S. Sudarmono, Pratiwi Pudjilestari Sufia Shalehah Sugito, Syailendra Karuna Suhariyati, Eli Sumarto, Sabaria Surya Dwira Susanti, Helmi Susanti, Lis Susanto, Deny Suyono Suyono Syahira, Khadijah Khansa Syaputra, Ramadhan Syaufuri, Intan Lhotifah Syavicky, Ahmad Reihan Syech Idrus Taufik Nugroho Toaha, Sahabuddin Tuti Alawiyah Tutik Lestari Virizky, Fayzha Walid, Ahmad Wawaimuli Arozal Wibisana, I GNG. Wirayuda, Adnan Wusthoa, Jumratul Yaqin, Moh. Ainul Yonada, Fitria Yuli Budiningsih Yulia Rosa Saharman Yuni Indriyanti Yurniati, Yurniati YUSNITA YUSNITA Zahra, Annisa Zulfia Memi Mayasari Zulkiffli Saleh