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All Journal Sodality: Jurnal Sosiologi Pedesaan Jurnal Pengolahan Hasil Perikanan Indonesia Jurnal Reviu Akuntansi dan Keuangan Bioma : Berkala Ilmiah Biologi Jurnal Telaah dan Riset Akuntansi Jurnal Kedokteran Brawijaya TRANSIENT: Jurnal Ilmiah Teknik Elektro Majalah Kedokteran Bandung DE JURE Jurnal Pendidikan IPA Indonesia JEJAK Lingua Jurnal Bahasa dan Sastra Jurnal Theologia Jurnal Penelitian Hutan dan Konservasi Alam Jurnal Kesehatan Jurnal Online Mahasiswa (JOM) Bidang Matematika dan Ilmu Pengetahuan Alam Jurnal Online Mahasiswa (JOM) Bidang Keguruan dan Ilmu Pendidikan EDUKASIA QUALITY QIJIS (Qudus International Journal Of Islamic Studies) Riset Manajemen dan Akuntansi Journal of Biomedicine and Translational Research Jurnal Komunikasi Hukum Brawijaya Law Journal : Journal of Legal Studies MEDISAINS Jurnal Rekayasa Sipil dan Desain STOMATOGNATIC- Jurnal Kedokteran Gigi Fakultas Pertanian Jurnal Sistem dan Informatika INTEKNA Jurnal Penelitian Humaniora Kajian Linguistik dan Sastra Majalah Obat Tradisional JOURNAL OF INFORMATICS AND COMPUTER SCIENCE JURNAL POENALE Pharmauho: Jurnal Farmasi, Sains, dan Kesehatan JSW (Jurnal Sosiologi Walisongo) Ziswaf : Jurnal Zakat dan Wakaf JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) The Indonesian Journal of Public Health Binus Business Review Konversi Jurnal Ilmiah Mahasiswa Ekonomi Akuntansi PROFESIENSI MNJ (Malang Neurology Journal) SASINDO BIOMA Jurnal ELTIKOM : Jurnal Teknik Elektro, Teknologi Informasi dan Komputer Jurnal Pendidikan Olah Raga Palapa: Jurnal Study Keislaman dan Ilmu Pendidikan Jurnal Riset Manajemen dan Bisnis (JRMB) Fakultas Ekonomi UNIAT Hikmah : Journal of Islamic Studies Religiï¿½: Jurnal Studi Agama-agama Jurnal Ilmu dan Riset Akuntansi Journal Of Vocational Health Studies Animal Production : Indonesian Journal of Animal Production Jurnal Penelitian Pendidikan IPA (JPPIPA) Kinetik: Game Technology, Information System, Computer Network, Computing, Electronics, and Control Jurnal ASET (Akuntansi Riset) AL-ATHFAL : JURNAL PENDIDIKAN ANAK Agregat: Jurnal Ekonomi dan Bisnis Sawala : Jurnal Administrasi Negara JURNAL SINEKTIK Buletin Farmatera Varia Justicia Jurnal Analisis Bisnis Ekonomi REKAMAN (Jurnal Riset Ekonomi Bidang Akuntansi dan Manajemen) Jurnal Keperawatan Silampari Marine Research in Indonesia Jurnal Keperawatan Muhammadiyah Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Al-sihah: The Public Health Science Journal Journal of Maternal and Child Health Prosiding Seminar Nasional Sains dan Teknologi Terapan Jurnal Kolaboratif Sains Media Keperawatan Indonesia Proceedings of the International Conference on Applied Science and Health At-Tafkir International Journal of Natural Science and Engineering JIMFE (Jurnal Ilmiah Manajemen Fakultas Ekonomi) CANTILEVER Jurnal Ilmu Kedokteran dan Kesehatan SCIENTIA JOURNAL Al-Amwal Jurnal Keperawatan Komprehensif (Comprehensive Nursing Journal) EduReligia : Jurnal Pendidikan Agama Islam Infokes : Info Kesehatan Jambura Journal of Health Sciences and Research Jurnal Pemberdayaan: Publikasi Hasil Pengabdian Kepada Masyarakat Prosiding SAKTI (Seminar Ilmu Komputer dan Teknologi Informasi) Journal of Humanities and Social Studies Proceeding - Sari Mutiara Indonesia International Conference on Health Jurnal Ilmu Keperawatan Jiwa Jurnal Perempuan ComTech: Computer, Mathematics and Engineering Applications CSRID (Computer Science Research and Its Development Journal) Unnes Journal of Public Health MANAGERIA: Jurnal Manajemen Pendidikan Islam JURNAL MEDIA HUKUM DAN PERADILAN Menara Ilmu Jurnal Suara Keadilan Jurnal Madani SPORTIVE: Journal Of Physical Education, Sport and Recreation Jurnal Penelitian IPTEKS E-Prodenta Journal of Dentistry JURNAL MUTIARA KESEHATAN MASYARAKAT Jurnal Pendidikan Teknologi Pertanian Jurnal Sains dan Teknologi Reaksi JCER (Journal of Chemistry Education Research) Kappa Journal Jurnal Keperawatan Priority Jurnal Ekonomi Manajemen Kumawula: Jurnal Pengabdian Kepada Masyarakat Jurnal Kesehatan Masyarakat dan Lingkungan Hidup Jurnal Pendidikan dan Konseling Contagion: Scientific Periodical Journal of Public Health and Coastal Health Jurnal Pengembangan Penyuluhan Pertanian Health Information : Jurnal Penelitian Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Bearing : Jurnal Penelitian dan Kajian Teknik Sipil Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Agrium Akbis: Media Riset Akuntansi dan Bisnis PREPOTIF : Jurnal Kesehatan Masyarakat JSR : Jaringan Sistem Informasi Robotik Journal of Artificial Intelligence and Innovative Applications (JOAIIA) Jurnal Doppler Jurnal Ners JOURNAL OF INFORMATICS AND COMPUTER SCIENCE Indonesian Journal of Pharmaceutical and Clinical Research Journal of Telenursing (JOTING) Jurnal Aisyah : Jurnal Ilmu Kesehatan Indonesian Journal of Global Health research Jurnal Penelitian Pendidikan, Psikologi Dan Kesehatan (J-P3K) Jurnal Scientia Budapest International Research and Critics Institute-Journal (BIRCI-Journal): Humanities and Social Sciences Edunomics Journal Caring : Indonesian Journal of Nursing Science JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Sylva: Jurnal Ilmu-ilmu Kehutanan KLIK: Kajian Ilmiah Informatika dan Komputer PRIMER (Prima Medical Journal) JAGO TOLIS : Jurnal Agrokompleks Tolis Jurnal EduHealth Jurnal Ekonomi Jurnal Info Sains : Informatika dan Sains Ahmar Metastasis Health Journal (AMHJ) Empiricism Journal Humantech : Jurnal Ilmiah Multidisiplin Indonesia BERKAT: Jurnal Pemberdayaan Masyarakat Nurse and Holistic Care Suloh : Jurnal Fakultas Hukum Universitas Malikussaleh Jurnal Ekonomi dan Bisnis Digital (MINISTAL) Jurnal Multidisiplin Madani (MUDIMA) International Journal of Islamic Education, Research and Multiculturalism (IJIERM) JAMAIKA: Jurnal Abdi Masyarakat KOMMAS: Jurnal Pengabdian Kepada Masyarakat Buletin Kedokteran dan Kesehatan Prima International Journal of Health and Pharmaceutical (IJHP) Abdi Jurnal Publikasi Yuris: Journal of Court and Justice Jurnal Mosfet Jurnal Sosial dan Sains Journal of Islamic Economics Lariba J-ABDIPAMAS (Jurnal Pengabdian Kepada Masyarakat) Journal of Community Health Provision Jurnal Natural Jurnal Keperawatan Soedirman (The Soedirman Journal of Nursing) Innovative: Journal Of Social Science Research Jurnal Pengabdian Masyarakat Bangsa Estudiante Law Journal Journal of Economics and Management Scienties Jurnal Mahasiswa Ilmu Kesehatan IJRETINA - International Journal of Retina LOGIC : Jurnal Ilmu Komputer dan Pendidikan Biner : Jurnal Ilmu Komputer, Teknik dan Multimedia OKTAL : Jurnal Ilmu Komputer dan Sains APPA : Jurnal Pengabdian Kepada Masyarakat Indatu Journal of Management and Accounting Haga Journal of Public Health (HJPH) Malahayati International Journal of Nursing and Health Science Journal on Pustaka Cendekia Informatika Lentera: Multidisciplinary Studies Tarbawi : Jurnal Studi Pendidikan Islami Ashlach : Journal of Islamic Education MCSIJ (Marine, Coastal and Small Islands Journal) : Jurnal Tugas Akhir Mahasiswa Ilmu Kelautan Folia Medica Indonesiana

Nasution, Ali Napiah

Universitas Prima Indonesia

Author-ID : 1233068

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Application of Clitoria ternatea L. Flower Extract Lotion in Preventing the Decrease in Collagen and Epidermis Thickness in Wistar Rats Skin Given Ultraviolet-B Rays Gracela, Ira; Girsang, Ermi; Nasution, Ali Napiah; Yuliansyah, Jeri; Putri, Riri Virzan
Jurnal Penelitian Pendidikan IPA Vol 11 No 3 (2025): March
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i3.10947

Exposure to ultraviolet-B (UV-B) light contributes to a decrease in skin collagen levels, which can cause premature aging. This study aims to evaluate the effectiveness of telang flower (Clitoria ternatea L.) extract lotion in maintaining collagen levels and epidermal thickness of UV-B-exposed rat skin. A total of 30 Wistar male white rats (200-250 g) were divided into six treatment groups: negative control (distilled water), positive control (Vaseline), and four treatment groups of telang flower extract lotion with concentrations of 0.2, 0.5, 0.75, and 1%. Mice were exposed to UV-B light (311 nm, 70 mJ/cm² per session) for 14 days with a total dose of 420 mJ/cm². The lotion was applied twice daily, before and after UV-B exposure. Evaluation was performed by measuring collagen content and epidermal thickness using histology staining. Statistical analysis used One-Way ANOVA or Kruskal-Wallis if assumptions were not met. The results showed that the treatment group with telang flower extract significantly increased collagen content and epidermal thickness compared to the negative control (p < 0.05), with a dose of 0.5% showing the highest effectiveness. In conclusion, telang flower extract lotion has potential as a photoprotective agent against UV-B-induced skin damage.

Pengaruh Dukungan Keluarga Terhadap Kepatuhan Pasien Gagal Ginjal Dalam Terapi Hemodialisis Nasution, Ali Napiah; Suandy, Suandy; Manurung, Rachel Gita Berlian
Empiricism Journal Vol. 6 No. 4: December 2025
Publisher : Lembaga Penelitian dan Pemberdayaan Masyarakat (LITPAM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/s1v4n576

Penelitian ini bertujuan untuk mengetahui hubungan antara dukungan keluarga dan kepatuhan pasien gagal ginjal kronik dalam menjalani terapi hemodialisis di RSU Royal Prima Medan. Penelitian ini dapat berkontribusi pada praktik klinis atau kebijakan rumah sakit dalam meningkatkan kepatuhan terapi hemodialisis. Penelitian menggunakan desain analitik dengan pendekatan cross-sectional, melibatkan 57 responden yang ditentukan menggunakan rumus Slovin. Data dikumpulkan melalui kuesioner mengenai dukungan keluarga dan kepatuhan pasien, kemudian dianalisis menggunakan uji korelasi Spearman. Hasil penelitian menunjukkan bahwa mayoritas responden berusia di atas 40 tahun, berjenis kelamin laki-laki, berpendidikan SMA, serta telah menjalani hemodialisis selama satu tahun. Nilai rata-rata dukungan keluarga sebesar 42 menunjukkan kategori baik, sedangkan kepatuhan terapi memiliki nilai rata-rata 3,5 yang juga termasuk kategori baik. Hasil uji statistik menunjukkan nilai koefisien korelasi r = 0,309 dengan p < 0,001, menandakan adanya hubungan positif yang signifikan antara dukungan keluarga dan kepatuhan pasien hemodialisis, meskipun kekuatan hubungan tergolong lemah. Hal ini menunjukkan bahwa semakin baik dukungan keluarga, semakin tinggi pula tingkat kepatuhan pasien dalam menjalani terapi. Temuan ini menegaskan pentingnya peran keluarga dalam dukungan emosional dan motivasi agar pasien tetap konsisten menjalani pengobatan. Sehingga disarankan untuk meningkatkan dukungan keluarga di lingkungan rumah sakit atau klinis. The Influence of Family Support on Adherence to Hemodialysis Therapy in Kidney Failure Patients Abstract This study aims to determine the relationship between family support and adherence in patients with chronic kidney disease undergoing hemodialysis therapy at Royal Prima Medan General Hospital. This study can contribute to clinical practice or hospital policy in improving adherence to hemodialysis therapy. The study used an analytical design with a cross-sectional approach, involving 57 respondents determined using the Slovin formula. Data were collected through a questionnaire regarding family support and patient adherence, then analyzed using the Spearman correlation test. The results showed that the majority of respondents were over 40 years old, male, had a high school education, and had undergone hemodialysis for one year. The average value of family support was 42, indicating a good category, while adherence to therapy had an average value of 3.5, also in the good category. The results of the statistical test showed a correlation coefficient value of r = 0.309 with p < 0.001, indicating a significant positive relationship between family support and adherence in hemodialysis patients, although the strength of the relationship was relatively weak. This indicates that the better the family support, the higher the level of patient adherence in undergoing therapy. These findings emphasize the importance of the family's role in emotional support and motivation so that patients remain consistent in undergoing treatment. So it is recommended to increase family support in the hospital or clinical environment.

Hubungan Dukungan Keluarga, Kepatuhan Berobat, dan Tingkat Stres Terhadap Keberhasilan Adaptasi pada Pasien Diabetes Mellitus dengan Neuropati Diabetik di RS Royal Prima Medan Nasution, Ali Napiah; Suandy, Suandy; Zuhdi, Muhammad Fikri
Empiricism Journal Vol. 6 No. 4: December 2025
Publisher : Lembaga Penelitian dan Pemberdayaan Masyarakat (LITPAM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/qanhp398

Diabetes Mellitus (DM) adalah penyakit kronis dengan prevalensi tinggi secara global, di mana neuropati diabetik merupakan salah satu komplikasi yang sering dialami. Penelitian ini bertujuan untuk menganalisis hubungan antara dukungan keluarga, kepatuhan berobat, dan tingkat stres terhadap keberhasilan adaptasi pada pasien diabetes melitus dengan neuropati diabetik di RS Royal Prima Medan. Penelitian ini menggunakan desain kuantitatif dengan pendekatan cross-sectional. Data dikumpulkan melalui kuesioner dukungan keluarga berdasarkan model Nursalam yang terdiri dari 12 pertanyaan, kuesioner MMAS-8 untuk mengukur kepatuhan berobat, dan instrumen untuk mengukur tingkat stres. Data yang diperoleh dianalisis menggunakan uji Chi-Square dan Uji Fisher Exact Test apabila data tidak berdistribusi normal. Hasil penelitian menunjukkan bahwa sebagian besar pasien mendapatkan dukungan keluarga yang tinggi (73,3%) dan menunjukkan adaptasi yang baik (83,3%). Meskipun uji statistik menunjukkan tidak ada hubungan yang signifikan antara dukungan keluarga dan adaptasi pasien (p = 0,460), secara klinis, dukungan keluarga tetap memegang peranan penting dalam mendukung adaptasi pasien. Faktor-faktor lain seperti usia, tingkat pendidikan, dan durasi penyakit juga berperan dalam proses adaptasi. Temuan ini mengindikasikan pentingnya dukungan keluarga dalam pengelolaan diabetes melitus dan menyarankan perlunya program dukungan keluarga di rumah sakit. Penelitian lanjutan disarankan untuk mengeksplorasi faktor-faktor lain yang mempengaruhi adaptasi pasien, seperti tingkat stres, pendidikan, dan tingkat keparahan penyakit. The Relationship between Family Support, Treatment Compliance, and Stress Levels on Adaptation Success in Diabetes Mellitus Patients with Diabetic Neuropathy at Royal Prima Hospital Medan Abstract Diabetes Mellitus (DM) is a chronic disease with high global prevalence, and diabetic neuropathy is a common complication. This study aims to analyze the relationship between family support, medication adherence, and stress levels on the adaptation success of diabetes mellitus patients with diabetic neuropathy at Royal Prima Hospital Medan. This study uses a quantitative design with a cross-sectional approach. Data were collected using a family support questionnaire based on the Nursalam model consisting of 12 questions, the MMAS-8 questionnaire to measure medication adherence, and an instrument to measure stress levels. Data obtained were analyzed using Chi-Square test and Fisher Exact Test when data were not normally distributed. The results show that most patients received high family support (73.3%) and demonstrated good adaptation (83.3%). Although statistical tests showed no significant relationship between family support and patient adaptation (p = 0.460), clinically, family support plays an important role in supporting adaptation. Other factors such as age, education level, and disease duration also influence adaptation. These findings indicate the importance of family support in diabetes management and suggest the need for family support programs in hospitals. Further research is recommended to explore other factors affecting patient adaptation, such as stress levels, education, and disease severity.

Antioxidant Activities and Potential Wound Healing Effects of Meniran (Phyllanthus niruri) Extract Gel Arif, Julio; Nasution, Ali Napiah; Nasution, Sri Wahyuni; Widowati, Wahyu; Dewi, Nindia Salsabila Mia; Kusuma, Hanna Sari Widya
Folia Medica Indonesiana Vol. 60, No. 1
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Highlights: 1. This study analyzed the potential of Meniran extract gel for wound healing therapy, a plant-based medicine that has not been thoroughly researched in the context of promoting a healthy lifestyle. 2. The analysis found that Meniran extract gel has antioxidant properties that can be used for wound treatment to improve human health. Abstract Research on the use of medicinal plants to treat numerous diseases has been widely conducted. However, for chronic wound healing, the availability of medicinal plants for treatment remains rare. Gels containing active plant-based compounds may provide a solution. Phyllanthus niruri, known as "meniran" in Indonesian, is a medicinal plant used traditionally to cure various diseases. This study aimed to examine the antioxidant activities of Meniran extract gel, potentially for wound healing. Meniran was extracted using 70% methanol and formulated into a gel. The Meniran gel was composed of three formulations: 3%, 4%, and 5% sodium carboxymethylcellulose (CMC-Na) supplemented with 5% Meniran extract. The quality of the gel was assessed based on homogeneity, spreadability, pH, and viscosity. This study utilized 2,2"²-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays to evaluate the antioxidant activity of Meniran gel at seven different concentrations through its scavenging capacities. The results were calculated to determine the median inhibitory concentration (IC50). Analysis of variance (ANOVA) and post-hoc Tukey's honestly significant difference (HSD) were used for statistical analysis (p < 0.05). The three Meniran gel formulations showed good quality with spreadability ranging from 5.37 to 5.59 cm, pH levels from 5.90 to 6.03, and viscosity from 9.080 to 9.230 cps. Higher gel concentrations led to an increase in the free radical DPPH- and ABTS-scavenging activities. The highest DPPH and ABTS assays were found at 1,000 Î¼g/mL with IC50 values of 69.72 Î¼g/mL and 20.15 Î¼g/mL, respectively. In conclusion, Meniran gel formulas exhibit good standards and have antioxidant properties suitable for wound healing therapy.

THE EFFECT OF DISCHARGE PLANNING ON PATIENT SATISFACTION: A SYSTEMATIC REVIEW Ginting, Liani Br; I Nyoman Ehrich Lister; Nasution, Ali Napiah; Anggeria, Elis; Hutomo, Rizky Aditya
Nurse and Holistic Care Vol. 5 No. 3 (2025): Nurse and Holistic Care
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/nhc.v5i3.7337

Background: Discharge planning is a continuous process carried out by nurses to help patients prepare for self-care after leaving the hospital. It involves collaboration among healthcare providers, patients, and families. Through health education, discharge planning provides essential information about the disease and its management to reduce the risk of relapse and rehospitalization. Objective: This systematic review aims to identify the effect of discharge planning implementation on patient satisfaction in the inpatient room. Design: This study employed a systematic review design to synthesize empirical evidence on the effect of discharge planning implementation on patient satisfaction in hospital inpatient settings. Data Sources: A systematic literature search was conducted using two electronic databases: Google Scholar and ScienceDirect. Articles published between January 2020 and April 2025 were identified using the keywords (“discharge planning” OR “discharge process” OR “transitional care”) AND (“patient satisfaction” OR “patient experience” OR “patient-reported experience”) AND (“hospital” OR “inpatient”). Review Methods: A total of 717 articles were initially identified. After removing duplicates and applying inclusion and exclusion criteria—full-text availability, English or Indonesian language, and quantitative study design—15 studies were included in the narrative synthesis. Article selection followed the PRISMA guidelines to ensure transparency and methodological clarity. The included studies were analyzed narratively to identify patterns, key themes, and overall effects of discharge planning on patient satisfaction. Results: Based on the results of several articles that fit the inclusion criteria, the implementation of discharge planning has a significant influence on the level of patient satisfaction. Conclusion: The implementation of discharge planning plays a crucial role in the hospital service system. Discharge planning can increase patient satisfaction with hospital services. Hospitals should develop standardized discharge planning protocols, strengthen nurse training programs, and ensure patient-centered implementation.

Patient Perceptions on The Role of Nurses in Discharge Planning for Post-Neurosurgery Patients: A Qualitative Study Br Ginting, Liani; Nasution, Ali Napiah; Anggeria, Elis
Caring: Indonesian Journal of Nursing Science Vol. 7 No. 2 (2025): Vol 7 No 2 2025 Caring: Indonesia Journal of Nursing
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijns.v7i2.22998

Nurses play a vital role and bear primary responsibility in discharge planning due to their constant interaction with patients and families. Research on discharge planning in Indonesia, particularly for post-neurosurgery patients, is still limited and rarely explored in depth, especially using a qualitative approach. Through a qualitative approach, this study was able to reveal the perceptions, challenges, and strategies of nurses that are often not seen in quantitative data. This study aims to analyse the role of nurses in discharge planning for families of patients who have undergone neurosurgery. This study employed a descriptive qualitative approach using phenomenological methods. The number of participants or informants based on saturation data or redundancy concepts can generally be achieved using purposive techniques. In-depth interviews were used in data collection. The data analysis process in this study used Colaizzi's approach. This study produced nine themes based on the Modified Concept of Meleis' Transitional Nursing Theory and Roy's Adaptive Nursing Model Theory. including medical education, clarity of information, involving the family, addressing concerns, support for access to follow-up services, follow-up support, patient/family readiness, post-discharge challenges, recommendations for services. The impact of discharge planning carried out by nurses prior to discharge home results in patients and their families being prepared to carry out nursing actions at home. Nurses should always be mindful of their role in the discharge planning process because quality discharge planning is not merely an “administrative procedure before discharge,” but rather a strategic investment. Keyword: Patient Discharge Planning, Neurosurgery Procedure, Nursing Role

Hepatoprotective Effectiveness Test of Salam Leaf Extract in Anthracyclin-Induced Rats Hariyento Halim; Ermi Girsang; Ali Napiah Nasution
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Cancer is the most often diagnosed disease in the world and the top cause of death. Doxorubicin is a widely used systemic therapy, although its efficacy is limited by dose-related toxicity, including haematological suppression, organotoxicity, and hepatotoxicity. Bay leaf is a commonly utilised plant in the community for treating and preventing many diseases because it includes secondary metabolites that are antioxidants such as phenolics, alkaloids, saponins, steroids, triterpenoids, and tannins. The purpose of this work is to characterise EEDS, identify its secondary metabolite content, and test its nephroprotective effect in doxorubicin-induced rats using SGPT and SGOT levels and liver histology. This is a laboratory experimental investigation using rats and comprises of treatment groups receiving 0.5% of CMC-Na, Nature E, or EEDS at doses of 100 mg/kgBW, 300 mg/kgBW, or 500 mg/kgBW, respectively, followed by doxorubicin. The results indicated that EEDS had 21.64 % water soluble material, 1.79 % total ash, 9.98 % water, 45.38 % ethanol soluble extract, and 0.39 % acid insoluble ash. EEDS included alkaloids, flavonoids, tannins, glycosides, saponins, and steroids/triterpenoids, as determined by phytochemical screening. EEDS doses of 100 mg/kgBW, 300 mg/kgBW, and 500 mg/kgBW can significantly lower SGPT by 34%; 52,46%; 59,31% and SGOT levels by 27,05%; 43,96%; 50,07% and can improve the liver histopathology of doxorubicin-induced rats by reducing pyknotic degeneration, inflammatory cell infiltration, bleeding, steatosis and sinusoidal dilatation with an effective dose of 500 mg/kgBW with a significant difference with the doxorubicin group followed by 0.5% CMC Na. The key to bay leaf ethanol extract has hepatoprotective activity.

Analysis of the Effect of Perceptions on The Distribution of Medical Services for BPJS Patients and Organizational Climate on Job Satisfaction of Doctors at Royal Prima Medan Hospital Rini Elvira Hutabarat; Adek Amansyah; Ali Napiah Nasution; Tan Suyono
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Job satisfaction among doctors is the main key to getting better health services. Changes in payment methods in the JKN era led to the dissatisfaction of specialists and general practitioners with the medical services received in BPJS patient care. This study analyzes the effect of perceptions about the distribution of medical services for BPJS patients on the job satisfaction of doctors. The research design used in this study was a descriptive analytic non-experimental study with a cross-sectional approach. The study was conducted at the Royal Prima General Hospital located in Medan City from May 2021 to August 2021. The sample in this study was selected using the purposive sampling method so that a sample of 77 people was obtained with the inclusion criteria of having worked for at least 2 years. Data were analyzed using the Chi-Square test and multiple logistic regression. The results showed that the total medical services received by general practitioners per month was 10 million rupiah. Meanwhile, the total number of medical visits and services received by specialist doctors per month is 25 million rupiah. Based on the results of the Chi-Square test, it can be seen that doctors' perceptions of medical services (number of medical services (p = 0.000), timeliness of delivery (p = 0.000), suitability of medical services with performance (p = 0.003), distribution system (p = 0.004), and transparency (p=0.011)) had a significant effect on doctor's job satisfaction. The results of multiple logistic regression test show that the variable with the greatest influence is the number of medical services. The variable number of medical services has a value of Exp(B) = 29,830 (95% CI 3,037-293,034) that means that respondents who state the number of good medical services are 29 times more likely to be satisfied than those who state that the number of medical services is less. Doctor's job satisfaction can be increased by the management's efforts to be more open to doctors regarding doctor's medical services, giving doctors the opportunity to improve their career paths, and conducting periodic evaluations of doctor's satisfaction through questionnaires.

The Effect of Motivation and Organizational Climate on Specialist Doctors’s Loyalty in Prima Medan Royal Hospital Mulya; Tan Suyono; Ali Napiah Nasution; Adek Amansyah
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

The role of specialist doctors in hospital services is large, making the bargaining position of specialist doctors high against hospitals. Various literature states that loyalty plays an important role in the formation of a person's decision in choosing a place of work and giving commitment. This study analyzes the effect of motivation and organizational climate on the loyalty of specialist doctors. This explanatory survey research uses a cross-sectional design. The study was conducted at the Royal Prima General Hospital Medan for 1 (one) month starting from July 2021 to August 2021. The sample was 50 people who were determined by the inclusion criteria were specialist doctors who had worked for at least 2 years. Data were analyzed using the Chi-Square test and multiple logistic regression. The results of statistical tests using Chi-Square show that motivation has a significant effect on the loyalty of specialist doctors, whereas the results of statistical tests show that physical and esteem needs have a p-value of less than 0.05. The organizational climate also affects the loyalty of specialist doctors, where the results of statistical tests show that flexibility, responsibility, standards, and commitment have p values less than 0.05. The results of the multiple logistic regression test show that the variable that has the greatest influence on the loyalty of specialist doctors is flexibility. With an Exp (B) value of 18,444 (95%CI 2,052- 165,779), Respondents who stated good flexibility had 18 times more loyal than those who stated poor flexibility. In conclusion, good flexibility will increase the loyalty of specialist doctors. This study concludes that motivation and organizational climate have a significant effect on the loyalty of specialist doctors. The aspect of flexibility in the organizational climate has the most influence on the loyalty of specialist doctors.

An Effect Virgin Coconut Oil Oral And Topical On Volume Decrease Of Foot Edema Of Male Wistar Flows Induced By –Caragenan Dzil Fikri; Ermi Girsang; Ali Napiah Nasution; Linda Chiuman
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Virgin Coconut Oil(VCO) is virgin coconut oil that is made enzymatically. The content of saturated fatty acids and flavonoid compounds in VCO can be used as an anti-inflammatory drug. This study aims to determine the activity of VCO as an anti-inflammatory. Anti-inflammatory activity was tested using the method of calculating the percentage of inflammation inhibition in white rat paws induced by intraplantar 1% carrageenan solution. The decrease in edema in the rat's feet was measured using a plethysmometer for 360 minutes. The results showed that VCO at a dose of 0.4 ml/200 g BW and 0.8 ml/200 g BW gave anti-inflammatory activity with the percentage of inflammation inhibition of 64.34 ± 9.90 and 52.66 ± 8, respectively. 94. The anti-inflammatory activity of VCO at a dose of 0.4 ml/ 200 g BW and a dose of 0.

Co-Authors ', Bustami ', Zulkarnain - Suratno A, Fitriana Ratih A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Abd. Rasyid Syamsuri Abdi Putra, Simeon Abdillah S., Abdillah S. Achmad Hidayatno Adam, Hikmah Adwin Ade Irma Lumbantobing Adek Amansyah Adelia Adelia, Adelia Aditya Azri Rizki Aditya Rochman, Aditya Adrian Adrian Adwindea, Ardana Afriani, Miskah Agatha Cecilia Maturbongs Aghus Sofwan Agus Budi Wahyudi Agus Hariyanto Ahmad Baihaqi Ahmad Ismail Alapi, Rahmat Aldi Tambunan Aldo Hermawan Suryana Aldy Valentino Alexander Angkasa Alfian Putra Alhumaira Oryza Sativa Alvin Abrar Harahap Amalia, Viki Aminuyati Amrullah Amrullah Ananda Safitri Andin Eka Safitri Anggraini, Tri Lidya Anita Merry Cisca Anita Zahra Anton Timur Jailani Harahap Anugrah Santoso, Hardi Anzib, Nuraini Arbi, Faisal Arfianti, Tri Arie - Vonikartika Arif, Julio Arigusman, Revalgi Ilham Aris Triwiyatno Aris, Anita Ariyansyah, Refy Arna Fransisca Mp Arravi, Rajulian Nurkholis Arviandi, Rizki Aryanie, Irne ashegaf, farhan taufiqurrahman Asnani Asnani Asri Widiya Sitompul Asyrun Alkhairi Lubis Atiqa Sabardila Atyanta Nika Rumaksari Awang Harsa Kridalaksana Awang Roni Effendi, Awang Roni Azhar Azhar Bagus Setiadi Baharuddin Baharuddin Bashar Awaluddin Nafsah Batara Sanjaya Harahap Baum, Gunilla Benny Rusli, Benny Binarwan Halim Br Ginting, Anissa Destryana Br Ginting, Liani Br Pelawi, Riri Sri Hagana Budy, Agung Cahya Buulolo, Netralman T.N Carles, Carles Carolina Carolina Ce, Win Cendy Juliana Cenggono, Melise Chandra Wilim Chiuman, Linda Chrismis Novalinda Ginting Christiana, Lia Cindy Stefanie Sinaga Clarissa Lister Corvis L. Rantererung Cut Elvira D. T. Chandra, D. T. Dadan Moh. Hamdani Dadang Redantan, Dadang Daniel Prem Raj Pandid Darjat Darjat Dede Falahudin Dedy Cahyadi, Dedy Delken Kuswanto Devi Damayanti Devi Yunita Devi Yunita Dewi Taurusyanti Dewi, Nindia Salsabila Mia Dhiwa Gemilang Pramadhani Diana Indrasanti Dio Damara Handoyo Dirgantara, Oscar Djohan Djohan Duha, Kristin Berlianta Duha, Sonya Marsela Pieta Dung, Le Quang Dung, Le Quang Dwi Andika Putra Dwi Hindarti, Dwi Dwi Rohma Nuraini Dyna Marisa Khairina Dzil Fikri Edy Setioko, Edy Efratiwi Marpaung Ekiyantini W, Ekiyantini Elang Pramana Putra Elianta, Peter Elis Anggeria Elizabeth, Riana Elvira, Cut Erida Nurahmi Ermi Girsang ERMI GIRSANG Ermi Girsang Ermi Girsang Ermi Girsang Ermi Girsang Ermi Girsang Ermi Girsang Ermi Girsang Ermi Girsang ETRINA MELINDA Eva Kristina Pelawi Evelyn Angie Fabian, Audric Faderina Komisia Fadillah, Adil Ridlo Fahlevy, Ridho Fahrul Agus Faizun, Nurul Fariz Septiawan Fauziyyah, Afifah Febri, Ririn Febyami Neimsegel Simatupang Feraera, Andrialius Fieterson, Kriahan Joel Fioni, Fioni Firman Pratama Firmansyah Nur Budiman, Firmansyah Nur Fiska Maya Wardhani Fitrayani, Fitrayani Fitri Yanti Fitriansyah, Rizko Prasada Fitrisia, Rina Florenly Florenly Frederick Frederick Galuh Ambar Sasi Gidion Franklin Simorangkir Ginting, Chrismis Novalinda Ginting, Crismis Novalinda Ginting, Liani Br Ginting, Sahna Ferdinand Giovani, Cut Maneka Girsang, Ermi Glorio ias Natanael Gracela, Ira Gunawan, Bambang Panji Gusnawati, Gusnawati H. Firman Halik, Moh. Nur Halima, Piyanto Handayani, Rr. Novita Wahyu Handoko, Erwin Hanjaya Hanna Sari Widya Kusuma, Hanna Sari Widya Hantarum, Hantarum Hapsari, Yolanda Aulia Harahap, Milna Chairunnisa Hariadi, Dadang Budi Harino, Hiroya Harino, Hiroya Hariyanto Halim Hariyento Halim Hartina Harun Joko Prayitno Hasan, Riyani Susan BT Hayatun Nufus Iriyanti Heliza Rahmania Hatta, Heliza Rahmania Herjayanto, Muh. Heru Joko Budirianto Hidayat, Alfa Manarul Hidayatullah Hidayatullah Hikmatul Mustaghfiroh, Hikmatul Hikmawati, Nita Hilal, Zaimah Hilyana, Siti Himawan, Noni Holan Dianju Melva Meinaria Sitanggang Hutabarat, Intan Audrey Alicia Hutagalung, Mangatas HP Hutomo, Rizky Aditya I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister I Nyoman Ehrich Lister Icuk Prayogi Ihsan Hanif Febriliayan Iin Purnamasari IKHTIARI, REFI Ikhwan, Afifah Ilham Surya Fallo Inneke F. M Rumengan Inoue, Koji Inoue, Koji Iqbal Maulana Akbar Ira Puspita Dewi, Ira Puspita Irawan, Desika Indra Irpan Kusyadi Irwan, Mulia Islahuddin, Islahuddin Islamiah, Nurul Istiqomah, Widya Jaka Sutresna Jaka Sutresna Jannah, Rusidatul Jauhari, Isynu Lutfhi Jeri Yuliansyah Jerry Fidelio Susanto Joko Daryatmo Jonizar, Jonizar jonizar, Jonizar Juan Alphanto Bemindra Julio Arif Kartika, Sri Kasmiati Kateni, Darul Kesuma, Farah Shyfa Kharisma Radhityas, Nuryasinta Kholil, A. Yusuf Kinoshita, Masato Kinoshita, Masato Koesmawati, Tiny Agustini Kopong, Agustina Kunzmann, Andreas Kunzmann, Andreas Kurniawan, Dedy Hendra Kusmadi Kusumadewi, Arum Grahini L. Ledoh, Dominggus Laksmi Irianti Larasati ., Larasati Lensari, Delfy Lestari Sukarniati Lestari, - Lestari, Rachmatika Liawati - Liawati Liawati Lie, Maylia Lie, Sukirman Lingga, Imelda Lister, Clarissa Lister, I Nyoman Ehrich Lister, I Nyoman Ehrich livana ph Lizuardi, Amiril Lubis, Windy Claudia Lumbantobing, Christina J. R. Esmaralda Lumbantobing, Christina JRE Lydia Yusuf M. Shabri M. Syafi’i, M. Syafi’i Makhfud Syawaludin Malaka, Muhammad Hajrul Malau, Reghita Claudia Maman Somantri Mangatas Silaen Mangesti, Yovita Arie Mansyur, Fakhruddin Manullang, Corry Yanti Manurung, Rachel Gita Berlian Mardiana Putri br. Tambunan Marhadi Saputro Maribeth, Annisa Lidra Maricella, Adrianie Martina Martina Masdar Helmi Masdul, Muh Rizal Matondang, Windri Mutiara Maya Sari Mutia Miarsa, Fajar Rachmad Dwi Mira Setiawati Miranda Sortalina Baringbing Mohandas Indradji Mohd. Nur Syechalad, Mohd. Nur Mokhamad Yusron Rafi Moriza Lesmana Muhamad Abduh, Muhamad Muhamad Agung Prasetyo Muhamad Ardy Kurniawan Muhamad Irvan Vadilah Muhamad Ridwan Wijaya Muhammad Agus Muljanto Muhammad Dimas Nugroho Muhammad Djafar Muhammad Ilyas Yusuf Muhammad Imaduddin Muhammad Irfannurroja Muhammad Nawal Hasya Muhammad Ridwan Muhammad Rivai Muhammad Syahdan Muhammad Yunus MUHAMMAD ZAINAL Muhammad Zainudin Muharam Natadisastra Mulia Saputra Mulya Munawar Agus Riyadi Munawaroh, Sitie Mustamin, Siti Walida Mutia, Maya Sari Muzzaki, Arisla Choirudin Nabilah Khairunnisa Nadia Artha Dewi Nadia Zenni Andari Nadiyah Santika Nafilah, Azimah Nurin Naimul Faizah, Naimul Naipospos, Bonaventura Nanda Parariski Purba Nandar Cundara, Nandar Nanik Setyawati Napitupulu, Agnes Nasution, Sri Lestari Ramadhani Natali, Oliviti Nindia Salsabila Mia Dewi Nita Anggraini, Nita Normawati Normawati, Normawati Novi Indrayati Nur Fitriyani Nurahmi, Nurahmi Nurfitri Ekantari Nurhaliza Arfadilla Nuriana, Wahidin Nursalam Nursalam Nurwijayanti Nury, Ahmad Sulthan Nyoman Wendri Oke Hariansyah Oktaviani, Emma Paftalika, Reiza Bani Perani Rosyani Pertiwi, Dora Hatika Poko, Feny Rizkia Prasetyo Adi Pratiastuti, Wike Prima Daniyati Kusuma Priyono Priyono Purbo Putra Sastaman B Putranto Manalu Putri Khaerunnisa Putri, Mutiara Kristiani Putri, Riri Virzan Rachma Puspitasari Rahimi, Armon Rahmadini, Rizki Rahmah Yulianti Rahman, Ibadur Rahmasari, Herisa Rahmat Padyawan, Andhy Raihan Ramadhani Rakhmanda, Andhika Ramada, Raynaldi Surya Ramadhan Efendi Ramadhani, Natalia Putri Ramjaun, Shaheen Bibi Rasidin Rasidin Rasul Raswandaru, Marsela Riska Ratna Dewi Ratna Widyawati Razki, Cut Danisha Reffanda Kurniawan, Reffanda Reh Malem br Karo Renaldi Revisdah Revisdah, Revisdah Ria Hartaty Rido Gunawan Ridwan, Ridwan Riko Mardani Saputra Riky Suherman Simanjuntak Rina Rizkia Rini Elvira Hutabarat Rio Antono Robbani, Hamdan Rochyatun, Endang Roizza Dema Nurikhwan Romadhon, Ahmad Heru Roni Sefia Rosianty, Yuli Rovi Pahliwandari, Rovi Rubiyatno Rubiyatno Rulli Rosandi Rustam HN, Muhammad S. Redjeki Sababuli, Jeklin M. Safwan Safwan, Safwan Sahidin . Sahna Ferdinand Ginting Said Musnadi Saipul Sihotang Salfa Nindya, Faradhina Salman, Abrar Mujahidin Salovetian, Marcelino Salwa Juani Adrasah Samliok Ndobe Samosir, Frans Judea Sari, Dina Meilita Sari, Laura Kartika Saripah, Dedek Satria, Brama Yoga Satrio Haryo Benowo Wibowo Savitri Sembiring, Mahral Effendi Sembiring, Rinawati Septya Maharani, Septya Setiawati, Suzzanna Shahdevi Nandar Kurniawan, Shahdevi Nandar Shelvi Eka Tassia Sihaloho, Hendra F. Silaen, Mangatas Simatupang, Veronica Triwindari Sinaga, Reza Audina Siregar, Oscar Solideo Siregar, Reza Arfan Siti Rahma Sitin Nurul Khasanah, Sitin Nurul Son Suwasono, Son Sri Lestari Ramadhani Sri Lestari Ramadhani Nasution Sri Lestari Ramadhani Nasution Sri Mulyati Sri Rezeki Sriatun Sriatun Sriminarti, Nurul Stephanie Raibalaki Suadi Suadi Suandy, Suandy Suci Erawati SUCI FERDIANA Sucy Hasfya Sugeng Riyanto Suherlina - Suherlina Suherlina, Suherlina - Sulistijanto, Eddy Sulistyoningrum, Harum Sumardi . Sumiati Sumiati Supardi Djasmani, Supardjo SUPRAPTO Supriati, Yulia Supriyanto Supriyanto Suriani Suriani Suryadinata Suryatama, Yahya Rizkiandra Susanna Halim Susi Susanti Suwandy Suwandy Suyono, Tan Suyono, Tan Syura, Asy T. Arie Setiawan Prasida Tambunan, Gempita Cahaya Aulia Tampubolon, Elisabet Tan Suyono Tandanu, Erny Tanjaya, Angela Tarigan, Muliate Taufan Hidayat Tcanty Indrianti Thomas Stefanus Kaihatu Tiara Nabila Nabati Tio, Susanthy Tjiawi, Midoro Tobing, Madeline Angeline Tri Atmoko Tri Putra, Kurniawan Triwarti, Hairul Triyoni Purbonegoro, Triyoni Ulina Karokaro Umar Ibrahim Valencia Yuwono Veranyca Chiuman Vijay Dhillon Vonikartika, Arie - Wahyu Widowati WAHYU WIDOWATI Wahyu Widowati Wahyuni Nasution wandi Wardana, Rico Ariesta Wardhani, Fiska Maya Wattayakorn, Gullaya Wattayakorn, Gullaya Welly Ria Utami Lubis Werfete, Rivaldy Alfrets Whalsen Duli Agus Lauh Wibawa, Iskandar Wibowo, Satrio Haryo Benowo Widya Pasca Amir Widya Pratiwi Widya Puspita Cahyani Widya Yanti Sihotang Widyaningsih Oentari Widyaningsih Oentari Widyastari, Elisa Wiedya Kristianti Angeline Wijaya, Joshua Andre Wildianti, Delia Winarni, Erni Winda Winarti Windraskinasih, Mutiara Wiranto Wiranto Wulan Dhari Yaasmiin nuhaa asa Putri Yakub Nasucha Yamamoto, Yu Yamamoto, Yu Yatsuzuka, Emi Yatsuzuka, Emi Yogi Rizky Pangestu Yogie Chandra Yolen Perdana Sari Yoridha Aulia Sinuraya Yosmina Tapilatu Yossi Diantimala Yuli Christyono Yuliana Yuliana Yuliansyah, Jeri Yulidar Yulidar Yulindasari Sutejo, Yulindasari Yundari, Yundari Yunike Yessica Ulina Yusof, Shahrizad Yusof, Shahrizad Yusuf, Lydia Zendrato, Arisman Zerry All Vindo Tarigan Zidan, Muh. 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