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All Journal International Journal of Applied Power Engineering (IJAPE) DIKSI Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences JURNAL SISTEM INFORMASI BISNIS Torani Journal of Fisheries and Marine Science BIMASTER Jurnal Pelita Pendidikan Majalah Kedokteran Bandung Mediator Jurnal Penelitian Komunikasi Journal of Biomedicine and Translational Research Nurani: Jurnal Kajian Syariah dan Masyarakat Jurnal Ilmu Kelautan Spermonde Jurnal Intelektualita: Keislaman, Sosial, dan Sains Mutiara Medika: Jurnal Kedokteran dan Kesehatan The Indonesian Journal of Occupational Safety and Health Berkala Kedokteran Muamalah JURNAL SIPIL SAINS Promotif: Jurnal Kesehatan Masyarakat Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Animal Production : Indonesian Journal of Animal Production JURNAL MEDIA INFORMATIKA BUDIDARMA UICELL Conference Proceeding BASIS (BAHASA DAN SASTRA INGGRIS) Pendas : Jurnah Ilmiah Pendidikan Dasar Penelitian Pendidikan Geografi Humanika PROSIDING SEMINAR NASIONAL PROGRAM PASCASARJANA Martabe : Jurnal Pengabdian Kepada Masyarakat JURNAL ILMIAH CAHAYA PAUD Jurnal Ilmiah Media Sisfo GEMA EKONOMI Jurnal Kesehatan Ibu dan Anak Journal of Pragmatics Research Jurnal Respirologi Indonesia Aquacultura Indonesiana Jurnal Respirasi (JR) Jurnal Review Pendidikan dan Pengajaran (JRPP) Dedikasi: Jurnal Pengabdian Masyarakat Al-Wardah: Jurnal Kajian Perempuan, Gender dan Agama NURSING UPDATE JURNAL ILMIAH ILMU KEPERAWATAN Asian Journal of Aquatic Sciences Jurnal Ilmiah Ilmu dan Teknologi Rekayasa Jurnal Ners Edukasi: Jurnal Ilmiah Pendidikan Anak Usia Dini Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Khatulistiwa Indonesian Journal of Global Health research Jurnal Inovasi Pendidikan dan Sains Ethical Lingua: Journal of Language Teaching and Literature Indonesia Berdaya Jurnal Pendidikan, Sains, Geologi, dan Geofisika (GeoScienceEd Journal) Tomini Journal of Aquatic Science Jurnal Pengabdian Masyarakat STKIP AL MAKSUM LANGKAT JURPIKAT (Jurnal Pengabdian Kepada Masyarakat) Journal La Bisecoman Jurnal Kependidikan: Jurnal Hasil Penelitian dan Kajian Kepustakaan di Bidang Pendidikan, Pengajaran dan Pembelajaran Jurnal Pengabdian Masyarakat Indonesia Jurnal Ilmiah Wahana Pendidikan JOURNAL LA MEDIHEALTICO Respiratory Science Bima Abdi: Jurnal Pengabdian Masyarakat Integral : Jurnal Penelitian Pendidikan Matematika Jurnal Ilmiah Pendidikan Visioner (JIPV) Journal of Natural Sciences Journal Of Khairun Community Services Anoa : Jurnal Pengabdian Masyarakat Sosial, Politik, Budaya, Hukum. Ekonomi Journal of Education Research Abimanyu: Journal of Community Engagement Diniyah: Jurnal Pendidikan Dasar Premium: Insurance Business Journal Az Zarqa': Jurnal Hukum Bisnis Islam Jurnal PRIMED:Primary Education Journal atau Jurnal Ke-SD An Indonesian Journal of Cancer Relevance: Journal of Management and Business Tsaqofah: Jurnal Penelitian Guru Indonesia Hulondalo Jurnal Ilmu Pemerintahan dan Ilmu komunikasi (JIPIK) CONSEN: Indonesian Journal of Community Services and Engagement Homeostasis: Jurnal Mahasiswa Pendidikan Dokter Indonesian Health Journal Jurnal Indonesia Sosial Teknologi Transformasi : Jurnal Penelitian dan Pengembangan Pendidikan Non Formal Informal Jurnal Pengabdian Kolaborasi dan Inovasi IPTEKS Coreid Journal Al-Mulk: Jurnal Pengabdian Masyarakat Kapuas Prosiding Seminar Nasional Biologi Cendikia Pendidikan Jurnal Ilmu Komunikasi dan Sosial Politik Jurnal Ilmiah IPS dan Humaniora (JIIH) Jurnal Ilmiah IPA dan Matematika (JIIM) Jurnal Pengabdian Kepada Masyarakat Meambo Kreasi: Jurnal Pengabdian Masyarakat Lire Journal (Journal of Linguistics and Literature) Jurnal PETISI (Pendidikan Teknologi Informasi) Jurnal Pendidikan Progresif Bambu Laut: Jurnal Pengabdian Masyarakat
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Journal : Jurnal Respirasi (JR)

Differentiation of Malignant Pleural Effusions from Lung Squamous Cell Carcinoma and Adenocarcinoma through FTIR Spectroscopy: A Prognostic Approach Madargerong, Vincentius Adrian; Suhartono, Eko; Oktaviyanti, Ika Kustiyah; Haryati, Haryati; Isa, Mohamad; Assagaf, Ali; Kusumawardhani, Erna; Nurrasyidah, Ira; Syafa’ah, Irmi
Jurnal Respirasi Vol. 11 No. 2 (2025): May 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.2.2025.114-122

Abstract

Introduction: Malignant pleural effusion (MPE) is common in cancer patients and is often caused by neoplastic involvement of the pleural surface. This study aimed to determine the utility of Fourier transform infrared spectroscopy (FTIR) spectral analysis and anatomical pathological differentiation in MPE, squamous cell carcinoma (SCC), and lung adenocarcinoma as prognostic predictors. Methods: This study used a cross-sectional design at Ulin General Hospital, Banjarmasin, involving advanced lung cancer patients with MPE. A non-probability sampling technique was used to recruit 30 patients. Fourier transform infrared spectroscopy was analyzed to evaluate anatomical pathology differentiation. Results: Differences were observed in the FTIR spectral ratios A1080/A1243 and A1080/A1170 between SCC and adenocarcinoma, with p-values of 0.026 and 0.022, respectively. Significant differences were also found in the A2959/A1545 ratio between well-differentiated and poorly differentiated adenocarcinomas, with a p-value of 0.023. The receiver-operating characteristic curve (ROC) indicated good predictive value for poorly differentiated adenocarcinoma at a cut-off value of 0.944, with a sensitivity of 50% and specificity of 100%. However, no significant correlation was found between FTIR absorbance and anatomical pathology differentiation in MPE due to SCC and lung adenocarcinoma. Conclusion: The FTIR spectral ratios A1080/A1243 and A1080/A1170 differentiate SCC from adenocarcinoma. Fourier transform infrared spectroscopy may be an adjunct to cytology, offering a more rapid and cost-effective method for differentiating MPE.
Vitamin D, Body Mass Index, and Total Lymphocyte Count in Drug-Sensitive and Drug-Resistant Tuberculosis Patients in Banjarmasin Riefani, Soraya; Juhairina, Juhairina; Isa, Mohamad; Kusumawardhani, Erna; Haryati, Haryati; Syam, Shaogi; Nurrasyidah, Ira
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.1.2024.14-22

Abstract

Introduction: Tuberculosis (TB) remains a global health problem that causes high morbidity and mortality. Based on its classification, TB is divided into drug-sensitive (DS) and drug-resistant (DR). Several risk factors susceptible to TB are malnutrition with low body mass index (BMI), vitamin D deficiency (VDD), and low total lymphocyte count (TLC) related to low immune status. This study aimed to examine the relationship between vitamin D (VD), BMI, and TLC in the TB population in Banjarmasin. Methods: This was an analytic observational study with a cross-sectional design. The total study sample was 42 patients, confirmed by rapid molecular testing, who had not been treated for TB in Banjarmasin from January to May 2023 and met the inclusion and exclusion criteria. Chi-Square and Fisher's exact statistical tests were used to see the relationship between VD, BMI, and TLC in DS TB and DR TB. Results: The median age of DS TB was 38 (24-52) years old, and DR TB was 51 (37-58) years old. Most of the gender was male (24 patients/57.1%). There was a statistically significant difference between VD and BMI in DS TB and DR TB (p = 0.048; p = 0.019). There was a significant relationship between VD and TLC in DS TB and DR TB (p = 0.048). Conclusion: VD and BMI significantly differed in DS TB and DR TB. There was a significant correlation between VD and TLC in TB patients.
How to Manage Lung Injury Related to Cancer Therapy? Haryati, Haryati; Saputra, Muhammad Hendi; Wati, Farah Fatma
Jurnal Respirasi Vol. 11 No. 1 (2025): January 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.1.2025.83-92

Abstract

Modern technology has improved our understanding of cancer biology, especially anti-cancer medicines from cytotoxic chemotherapy, radiotherapy, targeted therapy, and immunotherapy. Nevertheless, these treatments can result in significant pulmonary toxicities, including interstitial lung disease (ILD) and radiation-induced lung injury (RILI), which can result in a high rate of morbidity and mortality despite being less severe than injuries to other organ systems. Lung injury mechanisms occur through various pathways, such as immune-mediated damage and oxidative stress. Through clinical history and examination, imaging techniques such as high-resolution computed tomography (HRCT), and the necessity of eliminating other possibilities of respiratory symptoms, lung injuries due to cancer therapies can be identified. The management strategies are based on the severity of the condition and may include discontinuing the responsible agent, corticosteroid treatment, and supportive care. The challenge is early identification and management of these lung injuries due to the variability in patient responses and the lack of comprehensive guidelines. Therefore, awareness is needed to monitor lung health in cancer patients undergoing therapy.
The Time to Progression in Lung Adenocarcinoma Patients Receiving First- and Second-Generation EGFR-TKI in Indonesia Syahruddin, Elisna; Soeroso, Noni Novisari; Ananda, Fannie Rizki; Wulandari, Laksmi; Setijadi, Ana Rima; Ermayanti, Sabrina; Pratiwi, Suryanti Dwi; Infianto, Andreas; Andayani, Novita; Munir, Sri Melati; Pratama, Avissena Dutha; Kusumawardani, Ida Ayu Jasminarti Dwi; Haryati, Haryati; Duyen, Natalie; Hanif, Muhammad Alfin; Lim, Darren Wan-Teck
Jurnal Respirasi Vol. 11 No. 1 (2025): January 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.1.2025.22-30

Abstract

Introduction: Targeted therapy, particularly epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), is the first-line treatment for non-small cell lung cancer (NSCLC). However, drug resistance has grown in the last few decades. This study compared the progression time of lung cancer patients treated with first- and second-generation EGFR-TKI. Methods: Based on cytology and histological results, this cross-sectional study included 1,008 participants diagnosed with lung adenocarcinoma (LUAD) from 11 Indonesian Respiratory Centers. Every three months, the response to treatment was assessed using the Response Evaluation Criteria in Solid Tumours (RECIST) criteria in 1.1. Significant differences in the clinical features of the three TKI treatment groups were identified using logistic regression analysis, the median time to disease progression was estimated using the Kaplan-Meier technique, and independent prognostic factors related to the time to progression (TTP) were assessed using Cox proportional hazards regression. Results: This study examined 505 patients, the majority of whom were females (50.9%), never smoked (59.8%), diagnosed at an advanced stage (99.2%), and had an Eastern Cooperative Oncology Group (ECOG) scale of 0-1 (83.2%). Approximately 98.1% of patients were treated with afatinib (14.8%), erlotinib (18.6%), and gefitinib (66.1%) due to common mutations. The groups did not differ significantly (p>0.05). The median overall survival (OS) rate was 9 months. The time to LUAD progression in lung cancer was significantly impacted by poor performance (p=0.001). Conclusion: Epidermal growth factor receptor-tyrosine kinase inhibitor treatment can only prolong the TTP of LUAD by up to 9 months, and the performance scale when receiving the EGFR-TKI significantly affects the prognosis.
Co-Authors A, Nurnaningsih A. Fader, Wardah Abdul Mughits, Abdul Adithya, Rizky Adithya, Rizky Adithya Afifah Rahmania Afriansyah, Syafran Ahla, Nazelia Ahmad Muktamar B Ahmad, Fakhirah Ainun, Ainun Ajurid, Muhammad Akbar Fala Iqra Ali Assagaf Ali, Asmita Alsha Nazwa Alviani, Desi Rusiana Amal Khairan Amalia, Yuhana Amir, Istiqomah Ana Rima Setijadi Ananda, Fannie Rizki Andarini, Sita Andi Bungawati, Andi Andi Dahliaty Andini, Risky Suci Andriani, Diyah Iis Andriani,, Diyah Iis Anggun Anggun, Anggun Annisa Rosa Mora Harahap Arfiansyah, Mochammad Aris Arganita, Fidya Rahmadhany Arif Santoso Arlini, Fitriwi Asmar Yetty Zein, Asmar Yetty Asnawati Asnawati Assagaf , Ali Azis, Hasni Yulianti Azzahra, Wikha Baidhillah Riyadhi Buana, Lilik Swasta Angga Cangara, Arie Syahruni Cantika Sari Siregar CH Soenarjo, CH Chepy Perdana Dadang M Saleh, Dadang M Daniel Happy Putra Danuartha, Danuartha Dewi Astuti Diah kesumawati Diah Kusumawati, Diah Dian Anita Nuswantara Diany, Holly Dini Puji Anggraini Djawa, Yani Dody Dharmawan Trijuno, Dody Dharmawan Dona Marisa, Dona Dudung Juhana Duyen, Natalie DWI DAMAYANTI, ARUM Dwi Kirana, Dinda Dwi Rahayu, Puji Dwi Vernanda Edison Saade Effendi Nawawi, Effendi Effiyana, Arika Egilistiani, Rahmita eka rahmawati Eko Prasetyo, Nugroho Eko Suhartono Eku, Amran Elisna Syahruddin Ermayanti, Sabrina Erwin, Yolin Faanzir, Faanzir Fachruddin, Liestiaty Fajrianti, Dwi Farida Heriyani Farida Samad Febrian, Wenny Desty Ferryansyah, Ferryansyah Firdaus Hi Jahja Kunoli Firdaus, Muhammad Reyhan Firdawaty Marasabessy, Firdawaty Fujiati ., Fujiati Hadi, Amanda La Hadzal, Muhammad Ghozi Hajri, Waode Syahrani Halistin, Halistin Hanafiah Hanafiah, Hanafiah Hani, Umi Hanif, Muhammad Alfin Haryanto, Sri Hasan Sazali Hasnidar Hasnidar Hatidja, St. Heri Junaidi Herman Hesti Astuti Hi Sabatun, Adirahmadi Hi Umar, Suryani Hidayat, Moulid Hilal Anshary Humaira, Adhwa Husen, Risalmi Ida Ayu Jasminarti Dwi Kusumawardani Ika Kustiyah Oktaviyanti Indrawan Indrawan Infianto, Andreas Ira Nurrasyidah Irawati, Rika Isa Ansori Isa, Moh. Isa, Mohamad Ismail, Sri Marwa Iswan Iswan Jailani Syahputra Jamilah, Alya Maratun Jasminarti, Ida Ayu Joni Devitra, Joni Jubaedah, Eulis Juhairina, Juhairina Kababa, Nurul Izza Kardin, La Ode Kartawati Mardiah Kesuma, Desvan Hardian Komang Ayu Krisna Dewi Kurniasih, Ninik Kurniawan, Ferry Dwi Kusmana, Endang kusnan, adius Kusumawardhani, Erna Kusworo Adi La Ode Amaluddin, La Ode La Ode Nursalam, La Ode Laksmi Wulandari Lando, Asiyanthi Tabran Lim, Darren Wan-Teck Linda Suherma Linda Suherma M Nur Badawani Siregar M Pangestu, M M. J. Wahid, Santi Madargerong, Vincentius Adrian Maisari, Linda Masriah, Wulan Siti Nurul Maulina, Iin Mayasari, Ayudiah Puspita Meitria Syahadatina Noor Merakati, Indah Merlyana Dwinda Yanthi Mohammad Bakhriansyah Mohammad Rudiansyah Mohammed Rateb, Sheikh MS Conoras, M. Amrin MS Sumaryadi, MS Mubarak Mubarak Muhamad Taufiqurrahman, Muhamad Muhammad Ansar, Muhammad Muhammad Aprian Jailani Muhammad Rahmatul Burhan Muhammad Rusdi Muhammad Syahrizal Muhammad, Asri A Muhammad, Ibrahim Mustajidah, Mustajidah Mutmainnah, Putri Muttaqijn, M. Imam Nasution, Nurul Iflah Nelly Al Audhah Nihi, Sriyanti Nike Rahayu Nikman Azmin Noni Novisari Soeroso Nor, Muhamad Novianty, Riryn Novita Andayani, Novita Novita, Frinda Nugroho, Yohanes Sinung Nunu Nugraha Purnawan Nur Siswanti, Qanitah Nurdia, Fatmawati Nurfitria Khoirunnisa Nurhaeria, Nurhaeria NURHAMSA MAHMUD Nurhanna Harahap Nurjihan, Nabila Nurlan, Lani Nursapia Harahap Nurul Iman, Nurul Parhusip, Mual Bobby Enrico Permaini, Titi Prasetyo, Nugroho Eko Pratama, Avissena Dutha Pratama, I Wayan Adi Pratiwi, Suryanti Dwi Prayuana, Ratu Prichatin, Prichatin Pujiono Pujiono Purba, Azrina Purba, Natalia PURWANDARI, KIKI Puspitasari Puspitasari Putra, Andika Chandra Putranto, Algooth Putri, Afrida Novariani Putriutami, Citra Yuke Putro, Dwi Laksono Adi R. Simarmata, Eviriana Rachmawati W Siswadi, Rachmawati W Rahayu, Puji Dwi Rahman, Muhammad Natsir Rahmawati, Rahmawati Rahmawaty, Desi Ramadhaniati, Widya rangki, la Rasyid, Ramly Rian Piarna Riansyah, Firman Riefani, Soraya Riyadhi, Baidillah Rizki Nur Amelia Rochmawati, Nur Intan Rochmiatun, Siti Rodiyanah, Rodiyanah ROSITA WONDAL Rostiawati, Tia Rosyanti, Rosyanti Rudianda Sulaeman Rusmayani, Ni Gusti Ayu Lia Rynandi, Oscar Sahidun, Nurfitri Said, Rosmala D. Saida, Saida Samuel Lante, Samuel Sanjaya, Feri Santosa, Sonny Santoso, Andintia Aisyah SAPIL, NURSIN Saputra, Anugerah Saputra, Muhammad Hendi Sari Azhariyah Sari Dewi, Ratna Setiawan Assegaf Setyawan, Ungky Agus Shinta Kartika Nur Aisah, Shinta Kartika Siauta, M. Syamsu Sitepu, Setiana Sri Wahyuni Siti Hawa Siti Kaidah SJA Setyawati, SJA Skripsiana, Nika Sterina Slamet Rahayu Sri Melati Munir Sry Agustina Suardi, Nabila Subhan, Zarvin Ridho Sugiyatno Sugiyatno Suhartini Suhartini Suhayati, Lisa Sukma Zuliani Nasution, Unita Sukmadi, Arfiyan Suningsih, Suningsih Suryono Suryono Susan Andriana Susanty, Sri Sutarmo Sutarmo, Sutarmo Sutrisno, Sutrisno Syafa’ah, Irmi Syafitri, Anis Syafiuddin Syafiuddin Syam, Shaogi Syifa, Syifa Rizkita Ananda T, Said Nuwrun Tanjung, Efrilia Taswin R Tagama, Taswin R Taufiqurrahman Taufiqurrahman Taufiqurrahman Tedy Putra TEGUH ARIFIANTO, TEGUH Thasimmim, Said Nuwrun Tri Herdiawan Apandi Tri, Tri Herdiawan Apandi Tuharea, Karmila Umar Umar Unita Sukma Zuliani Nasution Usep Abdul Rosid Vandan Wiliyanti Wanda, Amalia Wati, Farah Fatma Wijaya, Masesa Angga Wijaya Yani Riyani Yani Riyani Yati, Mitra Yossi Oktorini Yuni Kusmiyati Yushinta Fujaya Yusmalina, Yusmalina Zahra, Rani Zainal Usman Zaini, Jamal Zuliana, Shella