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All Journal International Journal of Electrical and Computer Engineering Torani Journal of Fisheries and Marine Science Lintas Ruang: Jurnal Pengetahuan dan Perancangan Desain Interior Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Ilmiah Mahasiswa FEB Journal of Biomedicine and Translational Research Jurnal Ilmu Kelautan Spermonde JURNAL IPTEKS PEMANFAATAN SUMBERDAYA PERIKANAN Biomedical Journal of Indonesia Sinkron : Jurnal dan Penelitian Teknik Informatika Medical Laboratory Technology Journal Pendas mahakam : jurnal pendidikan dan pembelajaran Sekolah Dasar Jurnal Sains dan Informatika JURNAL MUQODDIMAH : Jurnal Ilmu Sosial, Politik dan Hummaniora Pendas : Jurnah Ilmiah Pendidikan Dasar Jurnal Ilmiah Mahasiswa Kedokteran Medisia Jurnal Pendidikan Matematika (JUDIKA EDUCATION) Fair Value: Jurnal Ilmiah Akuntansi dan Keuangan Jurnal Teknologi Sistem Informasi dan Aplikasi JURNAL PENDIDIKAN TAMBUSAI SRIWIJAYA JOURNAL OF MEDICINE ACTIVE: Journal of Physical Education, Sport, Health and Recreation Jurnal Teknologi Terpadu Jurnal Logistik Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Menssana Jurnal Mantik JABI (Jurnal Akuntansi Berkelanjutan Indonesia) Riyadhoh : Jurnal Pendidikan Olahraga Imajeri: Jurnal Pendidikan Bahasa dan Sastra Indonesia Scientia Psychiatrica Community Engagement and Emergence Journal (CEEJ) Journal of SPORT (Sport, Physical Education, Organization, Recreation, and Training) REMIK : Riset dan E-Jurnal Manajemen Informatika Komputer Jurnal PORKES RESLAJ: RELIGION EDUCATION SOCIAL LAA ROIBA JOURNAL Sriwijaya Journal of Surgery Open Access Indonesia Journal of Social Sciences Sriwijaya Journal of Ophthalmology Journal Informatic, Education and Management (JIEM) JURNAL PENDIDIKAN SAINS SOSIAL DAN AGAMA Eureka Herba Indonesia Jurnal Kesehatan Tambusai Jurnal Pengabdian Masyarakat: Humanity and Medicine PRAJA observer: Jurnal Penelitian Administrasi Publik Natural Sciences Engineering and Technology Journal Oikonomia: Jurnal Manajemen Open Access Indonesian Journal of Medical Reviews Indonesian Community Empowerment Journal Jurnal Abdimas Bina Bangsa Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Open Access Indonesia Journal of Social Sciences Bulletin of Economic Studies (BEST) Arkus Abditeknika - Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Kepada Masyarakat Patikala International Journal of Research and Applied Technology (INJURATECH) Muhasabatuna: Jurnal Akuntansi Syariah Journal of Informatics and Communication Technology (JICT) Journal of Anesthesiology and Clinical Research Journal Of Human And Education (JAHE) Journal of Medical Science; Jurnal Ilmu Medis Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh Scriptura: Jurnal Ilmiah Komunikasi Sustainability Science and Resources Journal International of Lingua and Technology Proceeding ISETH (International Summit on Science, Technology, and Humanity) Indonesian Journal Computer Science (ijcs) Journal Health Information Management Indonesian Indonesian Research Journal on Education Dikdimas : Jurnal Pengabdian Kepada Masyarakat Jurnal Muara Olahraga Jurnal Multidisiplin Sahombu Jurnal Pengabdian West Science Sinergi International Journal of Communication Sciences Jurnal Sosial, Sains, Terapan dan Riset (Sosateris) Technology and Society Perspectives (TACIT) Scientific Journal of Pediatrics Jurnal Spektrum Komunikasi Sriwijaya Journal of Radiology and Imaging Research Jurnal Rosenberg Teknologi Penangkapan Ikan Journal of Social Science Utilizing Technology Sriwijaya Journal of Internal Medicine Sriwijaya Journal of Obstetrics and Gynecology Sriwijaya Journal of Otorhinolaryngology Jurnal Pengabdian Sosial Informatics and Software Engineering (ISE) Jurnal Perikanan Terpadu Journal of Informatics and Communication Technology (JICT) Journal of Social Science Utilizing Technology Journal of Industrial Engineering Innovation Acta Psychologia ACTIVE: Journal of Physical Education, Sport, Health and Recreation Communica : Journal of Communication Bambu Laut: Jurnal Pengabdian Masyarakat Journal of Legal Contemplation Lentera: Journal of Islamic Studies Scientific Contributions Oil and Gas
RACHMAT HIDAYAT
Department Of Medical Biology, Faculty Of Medicine, Universitas Sriwijaya, Palembang, Indonesia
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Hubungan Kadar Alpha-Fetoprotein dengan Derajat Keparahan Hepatocellular Carsinoma Ulfa, Kamalya; Maghfirah, Desi; Dewi Mulia, Vera; Hidayat, Rachmat; Rezeki, Soraya
Journal of Medical Science Vol 7 No 1 (2026): Journal of Medical Science
Publisher : LITBANG RSUDZA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55572/jms.v7i1.291

Abstract

Hepatocellular Carsinoma (HCC) merupakan kanker hati primer yang paling sering ditemukan dan menjadi penyebab utama kematian akibat kanker di dunia. Alpha-fetoprotein (AFP) digunakan secara luas sebagai penanda tumor dalam diagnosis dan pemantauan HCC, di mana peningkatan kadar AFP diduga berkorelasi dengan derajat keparahan penyakit berdasarkan sistem klasifikasi Barcelona Clinic Liver Cancer (BCLC). Penelitian ini bertujuan untuk mengetahui hubungan antara kadar AFP dengan derajat keparahan HCC berdasarkan klasifikasi BCLC di RSUD dr. Zainoel Abidin Banda Aceh tahun 2024. Penelitian ini menggunakan desain observasional analitik dengan pendekatan cross-sectional, dengan data diperoleh dari rekam medis pasien HCC yang memenuhi kriteria inklusi. Sebanyak 40 pasien dijadikan sampel dan dibagi berdasarkan stadium BCLC (A–D), kemudian dianalisis menggunakan uji Kruskall Wallis karena data tidak berdistribusi normal. Hasil penelitian menunjukkan bahwa distribusi pasien terbanyak terdapat pada stadium BCLC B (37,5%) dengan mayoritas berjenis kelamin laki-laki dan rentang usia 14–74 tahun. Kadar AFP menunjukkan rentang luas (1,41–1000 ng/mL) dengan nilai yang meningkat seiring bertambahnya derajat BCLC dimana kadar AFP pada stadium A dan B yaitu 1,41-1000 ng/mL dan stadium C dan D yaitu 68,86-1000 ng/mL, serta terdapat perbedaan signifikan antara kadar AFP pada stadium A, B,C,dan D dengan p = 0,01. Penelitian ini menunjuukan terdapat hubungan bermakna antara kadar AFP dengan derajat keparahan HCC, di mana peningkatan kadar AFP pada stadium lanjut mencerminkan aktivitas tumor yang lebih agresif serta gangguan fungsi hati yang lebih berat. Pemeriksaan AFP dapat dijadikan indikator tambahan dalam menilai progresivitas HCC meskipun perlu dikombinasikan dengan penilaian klinis dan radiologis lainnya.
Digitalisasi Inventori Perancangan Aplikasi Manajemen Persediaan Berbasis Rapid Application Development Hidayat, Rachmat; Siregar, Andronias; Iriadi, Nandang; Hartana, Hartana; Santoso, Tri
Indonesian Journal Computer Science Vol. 5 No. 1 (2026): April 2026
Publisher : LPPM Universitas Bina Sarana Informatika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31294/ijcs.v5i1.11580

Abstract

Kemajuan teknologi informasi saat ini sangat pesat, komputer alat yang dirancang untuk membantu dan mempermudah tugas manusia, juga terus mengalami perkembangan besar, baik dari sisi perangkat keras maupun perangkat lunak. Pemanfaatan teknologi informasi ini mendorong berbagai perusahaan untuk meningkatkan efisiensi kerja melalui sistem yang terkomputerisasi. PT. Semestaindo merupakan entitas yang bergerak di sektor barang konsumen, khususnya dalam penjualan produk makanan ringan seperti snack dan biskuit. Dalam kegiatan operasionalnya, proses pengelolaan inventaris gudang masih dilakukan secara manual, yang sering menyebabkan berbagai masalah, seperti ketidakcocokan data persediaan, keterlambatan dalam penyusunan laporan, dan rendahnya efisiensi kerja. Keadaan ini dapat berdampak langsung pada kelancaran operasional perusahaan serta proses pengambilan keputusan oleh manajemen. Penelitian ini bertujuan untuk merancang dan menerapkan sistem informasi pengelolaan inventaris gudang yang mampu meningkatkan efektivitas dan efisiensi dalam pengelolaan stok barang. Metode pengembangan sistem yang digunakan adalah Rapid Application Development (RAD), karena metode ini menekankan pada kecepatan dalam proses pengembangan, keterlibatan aktif pengguna, serta fleksibilitas dalam menyesuaikan kebutuhan sistem. Tahapan penelitian meliputi perencanaan kebutuhan, desain sistem, pembangunan aplikasi, dan tahap implementasi. Sistem yang dikembangkan bersifat web-based dengan fitur utama seperti pengelolaan data produk, transaksi barang masuk dan keluar, pemantauan stok secara real-time, serta pelaporan persediaan secara otomatis. Hasil pengujian fungsional menunjukkan bahwa semua fitur pada sistem berjalan sesuai dengan kebutuhan pengguna yang telah ditentukan pada tahap Perencanaan Kebutuhan. Berdasarkan hasil pengujian dan validasi pengguna selama tahap implementasi, sistem informasi pengelolaan persediaan yang dibangun dengan metode RAD membantu menjadikan pengelolaan stok gudang lebih terstruktur, mempermudah proses rekonsiliasi data, serta menyediakan informasi yang diperlukan dalam proses pengambilan keputusan manajerial.
MANAGEMENT OF THE POLITICAL PARTY INFORMATION SYSTEM (SIPOL) APPLICATION AT THE INDEPENDENT ELECTION COMMISSION, BANDA ACEH Hidayat, Rachmat; Yusri Razali; Nanda Ermanda; Kurnia
Journal Informatic, Education and Management (JIEM) Vol 8 No 2 (2026): AUGUST
Publisher : STMIK Indonesia Banda Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61992/jiem.v8i2.349

Abstract

The Political Party Information System (SIPOL) application functions as a supporting tool to facilitate decision-making, ensure data organization, enable data collection, storage, distribution, and provide access to information. The involvement of Information Technology (IT) through the SIPOL Management Information System (MIS) in the verification process of political parties reflects the digitalization of electoral stages, producing adaptive and modern verification of party documents toward efficiency and effectiveness. The writing method employed combines a qualitative descriptive approach, based on experiences and observations during the 2024 General Election, with a quantitative descriptive statistical approach to determine the extent of SIPOL’s role in effectively and efficiently verifying political parties. The findings indicate that the SIPOL application plays a strong and dominant role in realizing organizational integration and coordination, knowledge and learning management, risk management and compliance, as well as supporting decision-making. Furthermore, SIPOL demonstrates a very strong and highly dominant role in enhancing efficiency and productivity, as well as improving collaboration and communicatio
The Potential, Structure, and Effectiveness of the Local Tax System in Strengthening Local Own-Source Revenue (PAD) in Kotabaru Regency Hamid, Ismar; Rahman, Mizan Ikhlasul; Srihardjanti, Rurien; Hidayat, Rachmat; Hidayah, Sri; Arqam, Muh.; Baihakki, Fajar; Sabar, Wardihan
Bulletin of Economic Studies (BEST) Vol 5 No 3 (2025)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/best.v5i3.64015

Abstract

Local own-source revenue (PAD) represents a core component of regional fiscal capacity and an essential indicator of subnational fiscal sustainability. This study examines the potential, revenue structure, and performance of local taxes in strengthening the local fiscal capacity of Kotabaru Regency. The analysis is based on secondary data on local tax revenues for the 2020–2024 period obtained from the Regional Revenue Agency of Kotabaru Regency. The empirical approach combines an assessment of tax composition and sectoral contributions, an evaluation of revenue target achievement, and trend and medium-term projection analysis using a logarithmic specification. The findings reveal that the local tax revenue structure in Kotabaru Regency is highly concentrated in Street Lighting Tax, Non-Metal and Rock Mineral Tax, and the Land and Building Rights Acquisition Duty (BPHTB), indicating a strong sectoral dependence on energy and extractive activities. While aggregate tax performance appears relatively strong, with average realizations exceeding annual targets, considerable heterogeneity is observed across tax instruments. Service-based and locally embedded taxes exhibit comparatively weak performance, pointing to untapped local tax capacity. The logarithmic trend estimates suggest a deceleration in revenue growth, consistent with diminishing returns in mature tax bases. These results imply that future fiscal strengthening should prioritize potential-based revenue planning, administrative efficiency and compliance enhancement, and diversification of the local tax base to improve regional fiscal resilience.
Network-Pharmacology-Guided Validation of Phyllanthus niruri Nephroprotection Against Doxorubicin: An In Vitro–In Vivo Translational Study Rachmat Hidayat; Vania Delma; Indri Yani Septiana
Eureka Herba Indonesia Vol. 6 No. 2 (2025): Eureka Herba Indonesia
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/ehi.v6i2.140

Abstract

Doxorubicin is a corner-stone anthracycline chemotherapeutic whose clinical utility is constrained by dose-limiting nephrotoxicity, and no approved pharmacological prevention currently exists. Phyllanthus niruri L. (Family Phyllanthaceae) — locally known in Indonesia as meniran — is a phytotherapeutic herb whose constituents (phyllanthin, hypophyllanthin, quercetin, rutin, gallic acid, and corilagin) target oxidative-stress and inflammatory pathways implicated in doxorubicin renal injury. We applied a tiered translational design: (i) network-pharmacology discovery using SwissTargetPrediction, TCMSP, GeneCards, and OMIM intersected six P. niruri active compounds with 842 nephrotoxicity-associated genes, identifying six hub targets (TNF, IL6, NFKB1, CASP3, BAX, BCL2) and four enriched KEGG pathways (TNF signaling, MAPK, PI3K-Akt, Apoptosis); (ii) in vitro validation in HK-2 human proximal tubular cells exposed to doxorubicin (2 µM, 24 h) with or without standardised P. niruri 70% ethanolic extract (25, 50, 100 µg/mL); and (iii) in vivo validation in 48 male Sprague-Dawley rats (eight per arm) given a single intraperitoneal dose of doxorubicin (15 mg/kg) and oral P. niruri at 100, 200, or 400 mg/kg/day for 14 days. P. niruri produced a dose-dependent rescue of HK-2 viability (84.6% at 100 µg/mL versus 41.8% in doxorubicin-only controls; p < 0.001) and reduced serum creatinine, blood urea nitrogen, urinary KIM-1, and NGAL by 55–70% at the 400 mg/kg dose with concordant restoration of glutathione and superoxide dismutase. Network-pharmacology hub targets showed transcriptionally coherent modulation. The findings support standardised P. niruri ethanolic extract as a mechanism-anchored herbal candidate for adjunctive prevention of doxorubicin-induced kidney injury, warranting clinical translation.
Co-Authors A. Heri Riswanto Aan Hardiyansah Abdul Mahatir Najar Abdulwahab Hakimi Abu Bakar Abu Bakar Abudarda, Andi Risda Fitrianti Achmar Mallawa Adnindya, Rulan Agus Indra Jaya Agus Junaidi Agus Junaidi Agustian, Kresnawidiansyah Ahadi Aulia Rahman Ahmad Ahmad Ahmad Ahmad Fatoni Ahmad Salim, Ahmad ahmad yani Ahmad Zain Sarnoto Ahmad, Arfandi Aji, Muhammad Pramono Alhan, Khusni Alvian, M. Andri Anang Tribowo Andayani, Nurfitri Andi Alfa Reza Andi Farmadi Andiani, Lia Andres Andres Andriana, Nadila Andronias Siregar Annisa Wimaulia Azlin Anuar, Arman Bin Aprilyanti, Cindy Apriwandi . Arifin, Nurdin Arindi Maretzka Arqam, Muh. Aryanto, Hermawan Noval Asep Nugraha, Asep Aswandi Aswandi, Aswandi Ayeshah A Rosdah Azakhia, Yolanda Citra Baharuddin Baharuddin Baihakki, Fajar Bainamus, Putri Milanda Bella Stevanny Bemba, Tonia Buchari Buchari Budi Pratiti Burhan, Ahmad Syarif Carla R Marchira Catherine Christine, Debbie Cinthya Callathea Dahlan, Dadang - Dariyanto, Erwin David Usman Debby Handayanti Harahap Dessa, Rima Dewi Mulia, Vera Didi Rosiyadi Djoko Widodo Edith Humries edy susanto Ella Amalia, Ella Ellya Verawati Elsa Iskandar Erizka Rivani Erlina Erlina Erma Agusliani Ester G Pansserga F, Zaeturohmah Fahcreza Faisal Syahputra, Faisal Fajarwati, Lia Fathonah, Andina Nur Fatmawati Fatmawati Fatmawati Febrian, Rivan Fildzah Hashifah Taufiq Fiona Widyasari Firdaus Muhammad Firjatullah, Andhika Fauziana Griselda Griselda Hadi, Dudi Abdul hadi, marwan Hammy, Hammy Hamzah, Fajri Handayani, Lisa Hani Subakti Hartana, Hartana Haryanto Haryanto Herman Paninggiran Hermansyah Hermansyah Hermansyah Herry Hasnawi Herwansyah Hidayah, Sri HUSNUL KHOTIMAH Ichsan Ridwan Ichsan, Amirul Ika Kartika Ikrima Ikrima Ilahi, Rahmat Imam Pribadi Indri Yani Septiana Inggarsih, Rara Irawan Sastradinata Irawan Sastradinata Irham Irham Irsan Saleh Ismar Hamid Iwan Setiawan Jakariya Jamalullail Jayawarsa, A.A. Ketut Jerni Joko Marwoto Joko Marwoto Julian Sigap Rosadi Suwarso Juniarta, Teguh Junoretta Haviva Ernanto Kahar, Irsan Kahar, Irsan Kahar Kashardi, Kashardi Kemas Abdul Mutholib Luthfi Kemas Ya'kub Rahadiyanto Krishna, Hidan Bayu Krisna Murti Kumba Digdowiseiso, Kumba Kurnia KURNIA KURNIA, KURNIA Lestari Barus, Irene Sukma Linda Purnama Listianingsih, Lona Lusia Hayati Lusia Hayati Lusia Hayati Lusia Hayati Lusia Hayati, Lusia Luthfi, Kemas Abdul Mutholib M. Baqir M. Yogi Riyantama Isjoni Maghfirah, Desi Mahmuddin Mahmuddin Mail, Abdul Maisya, Irin Makbruri Amin Malik, Aulia Januar Maria Margareth Wilson Marlinda, Dwi Martino Dwi Nugroho MARYANTI, LILIS Maslukin, Maslukin Mauladan, Ravy Maulana Saputra Maulana, Fahrul Maximillian Wilson Meilinda, Salsa Rizkia Mgs Irsan Saleh Mgs Irsan Saleh Mirna Dianita Mizan Ikhlasul Rahman Muallin, Muallin Mubarok, E. Saefuddin Muhammad Anzarach Pratama Muhammad Bima Muhammad Damar Udin Muhammad Irsan Saleh Muhammad Reagan Muhammad Reagen Muhammad Ridwan Muhammad Rifani, Muhammad Muhammad Rizky Hidayatullah Muhammad Yusril Syam Muhlis Muhlis Mukti Zainuddin Murlena, Murlena Muthia, Putri Muthia, Putri Nadia Khoirina Najla Khairunnisa Nanda Ermanda Nandang Iriadi Nani Solihati Nasriandi Nasriandi Ninuk Riesmiyantiningtias Nita Parisa Noorzaman, Sandi Noviyan, Rizky Dwi Nur Ainun Nur Riviati, Nur Nur Saqinah Galugu Nur, Suaib Nurdin, Muh Nur Ihlas Nurdina, Mutia Nurhasanah Nurhayati, M Sinta nurliah, nurliah Nurpahni, Siti Salma Nurrahmah, Andi Nurwijayanti Oktaviyani, Hikmatul Olivia Azalia Putri Pajarianto, Hadi Pamungkas, K J paosan, ahmad Patricia Wulandari Patry, Him Petty Purwanita Poku, Ham pongtiku, ita Prakarsa, Bambang Pramono, Yacob Agung Prayudhi, Risa Prihatina Anjela Purnamasari, Septi Puspa Sari, Puspa Puspa Zulaika Puspita, Sabrina Diah Puspitasari, Andini Putra, Suadi Sapta Putri Muthia Rachman, Andry Arifian Rachmat Hidayat Raden Ayu Adelia Safitri Raden Sunita Radiyati Umi Partan Radjikan Rahayu, Rosi Rahma, Wahidatul Qhoiruh Rahman, Ahadi Aulia Rahman, Ahadi Aulia Rahman, Alfi Rahmat Nur Rahmat Rais Rahmat Saleh Raihan Aqiilah N.L. , Andi Ahmad Ramadana, Radiyah Ramadhan, Hamzah Ramadhani, Anjas Ramli, Musdalifah Rara Inggarsih Rara Inggarsih Rashidah Unaib Al Zayid Rasyidah Jalil Reisha Notonegoro Resva Meinisasti Rety, Alghazali Riani Erna Rijaluddin, Khalid Rima Rachmawati Riri Juliantika Risnanosanti Risnanosanti Riswanto, A Heri Riswanto, A. Heri Riswanto, Andi Heri Riswanto, Heri Sabur, Baharuddin Safi'i, Imam Sahidan Sahidan Sahidan Sahidan Sahni Putri, Andi Rani Saksitha, Deassy Arestya Salni Salni Saman, Saman Samsuri, Fhadil Hidayat Sapinah, Pipin Sarah Sari , Windy Dian Sari H. S., Maharani Puspita Sari, Anggi Psutpita Sari, Windy Dian Sarmila, Sarmila Sarnato, Ahmad Zain Satriansyah , Arief Sekarini, Ratih Ayu Sepang, Rosa Marten Septi Purnamasari Septi Purnamasari SEPTIAN, DIAN Seruni, Seruni Shalita Dastamuar Shina Abdulkadir Sony Sanjaya Sonya Syarifah Soraya Rezeki Sri Nita Sri Nita Sri Nita Sri Nita, Sri Sri Tuti Rahmawati Sri Vandayuli Riorini Srihardjanti, Rurien Sry Agustina St. Aisjah Farhum, St. Aisjah Sudaramanto, Bagus Sujud, Atsari Surya Ade Saputera Surya Darma Surya Darma Syahira, Yowanda Aviva Syarif Burhan, Ahmad Tanjung, Enha Syahrul Taufiq Indera Jayadi Tiara Fatrin Tri Santoso Triwani Triwani Triwani Tungki Pratama Umar Tungki Pratama Umar Tunru, Andi Alif Udi Rusadi Ulfa, Kamalya Uswatun Hasanah Vania Delma Veithzal Rivai Zainal Wahyudin Wahyudin Wardani, M. Fikri Wardiansyah Wardihan Sabar Wiganepdo, Suryatno Wijaya, Maya Septa Winda Ramadianti, Winda Wirna, Risalah Sabila Yeni Agustin Yuliansyah, Chandra Yundari, Yundari Yuni sahruni, Ade Yusnaini Yusnaini Yusnia Budiarti Yusri Razali Yusril Yusril Zaidan, Naufal Muhamad Zakaria, Khairunnisa Zen, Agustian Ziske Maritska