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All Journal JPMS (Jurnal Pendidikan Matematika dan Sains) INOTEKS : Jurnal Inovasi Ilmu Pengetahuan, Teknologi, dan Seni RADIASI: Jurnal Berkala Pendidikan Fisika Jurnal Keperawatan Indonesia Masalah-Masalah Hukum LAW REFORM Journal of Language and Literature Prosiding KOMMIT Prosiding PESAT Jurnal Pendidikan dan Pembelajaran Khatulistiwa (JPPK) Jurnal Pendidikan Sosiologi dan Humaniora Jurnal Visi Ilmu Pendidikan Jurnal Hukum PRO JUSTITIA Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Jurnal Pendidikan Fisika Indonesia Althea Medical Journal Jurnal Biologi dan Pembelajarannya (JBP) Indonesian Journal of Cancer Chemoprevention JURNAL ILMIAH PENDIDIKAN FISIKA AL BIRUNI Jurnal Media Hukum Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) BERITA BIOLOGI JURNAL BIOLOGI INDONESIA ZOO INDONESIA Jurnal Inovasi dan Pembelajaran Fisika Jurnal Penelitian Pembelajaran Fisika Briliant: Jurnal Riset dan Konseptual Universa Medicina Al Qodiri : Jurnal Pendidikan, Sosial dan Keagamaan Jurnal Maneksi (Management Ekonomi Dan Akuntansi) Smart Medical Journal Ajudikasi : Jurnal Ilmu Hukum Jurnal Ilmiah Pendidikan Fisika Jurnal Kedokteran dan Kesehatan Paedagoria : Jurnal Kajian, Penelitian dan Pengembangan Kependidikan JCES (Journal of Character Education Society) Biosaintifika: Journal of Biology & Biology Education Jurnal Skala Kesehatan LINGUISTIK : Jurnal Bahasa dan Sastra ABDIMAS SILIWANGI JPF : JURNAL PENDIDIKAN FISIKA Jurnal Pendidikan Ekonomi (JURKAMI) Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Sciences) Jurnal Ilmiah Keperawatan Sai Betik Indonesian Journal for Health Sciences (IJHS) Jurnal Pendidikan Fisika dan Teknologi Jurnal Ilmiah Galuh Justisi JCPS (Journal of Current Pharmaceutical Sciences) YARSI Medical Journal Jurnal IDAMAN (Induk Pemberdayaan Masyarakat Pedesaan) Kasuari: Physics Education Journal (KPEJ) Majalah Kesehatan Pharmamedika Majalah Sainstekes Warta Ikatan Sarjana Komunikasi Indonesia Medika Alkhairaat : Jurnal Penelitian Kedokteran dan Kesehatan Science Education and Application Journal Jurnal Ilmiah Edunomika (JIE) ADIL : Jurnal Hukum Gravitasi: Jurnal Pendidikan Fisika dan Sains Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Metafora: Education, Social Sciences and Humanities Journal Jurnal Abdi Insani AS-SABIQUN: Jurnal Pendidikan Islam Anak Usia Dini Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Khatulistiwa Jurnal Surya Kencana Dua: Dinamika Masalah Hukum & Keadilan Jurnal Darma Agung Jurnal Riset Pendidikan Fisika Medicra (Journal of Medical Laboratory Science/Technology) Jurnal Pendidikan Dasar Perkhasa Pena Medika : Jurnal Kesehatan Jurnal Pengabdian kepada Masyarakat Nusantara Nusantara Science and Technology Proceedings Zoo Indonesia Jendela Pendidikan ABDIMASY: Jurnal Pengabdian dan Pemberdayaan Masyarakat DEDIKASI PKM Jurnal Kewarganegaraan Jurnal Ilmiah Wahana Pendidikan Respiratory Science Jurnal Res Justitia : Jurnal Ilmu Hukum COMMUNITY : Jurnal Pengabdian Kepada Masyarakat Jurnal Kesehatan Gigi dan Mulut (JKGM) Jurnal Citra Pendidikan Biospektrum Jurnal Biologi Journal of Oral Health Care Jurnal Ilmu Medis Indonesia AKADEMIK: Jurnal Mahasiswa Humanis Journal Of Human And Education (JAHE) PROSIDING SEMINAR NASIONAL FISIKA (E-JOURNAL) DHeJA Makara Journal of Health Research Info Abdi Cendekia Jurnal Citra Pendidikan Anak Junior Medical Journal Jurnal Pengabdian Kepada Masyarakat Innovative: Journal Of Social Science Research Jurnal Ilmiah Keperawatan Gigi Jurnal Hukum & Pembangunan Journal of Community Empowerment for Multidisciplinary (JCEMTY) Maneggio Jurnal Ruhul Islam Jurnal Pembelajaran dan Ilmu Pendidikan Jurnal Edukasi Ekonomi Seroja Husada: Jurnal Kesehatan Masyarakat ASSYIFA: Jurnal Ilmu Kesehatan Health Access Journal Jurnal Cahaya Edukasi Jurnal Pendidikan dan Pengembangan Sumber Daya Pertahanan Jurnal Citra Pendidikan Lex Librum : Jurnal Ilmu Hukum Jurnal Keperawatan Terapan
Endang Purwaningsih
Fakultas Kedokteran, Universitas YARSI
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Ethanolic periwinkle leaf extract reduces telomerase expression in T47D cancer cells Endang Purwaningsih; Etty Widayanti; Yulia Suciati
Universa Medicina Vol. 34 No. 2 (2015)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2015.v34.79-86

Abstract

BACKGROUNDCancer cells have a relatively high telomerase activity and a lower p53 protein expression than normal cells, so that cancer cells have the ability to continue to proliferate and do not undergo apoptosis. One of the cancer treatments is chemotherapy using bioactive ingredients from synthesis or isolation of natural materials. One of the plants that have potential as anticancer agent is periwinkle (Catharanthus roseus L). The research objective was to evaluate the effect of ethanolic periwinkle leaf extract against p53 protein and telomerase expression in T47D cancer cells.  METHODSAn experimental study with controls was conducted involving T47D breast cancer cells. They were divided into 3 groups (control, ½ dose of IC50/26.849 µg/mL, and one dose of IC50/53.699 µg/mL) at a cell density of 1 x 104 cells/well. Expression of p53 and telomerase was measured by the immunohistochemistry method. Data were analyzed using one-way ANOVA followed by a multiple comparison test.RESULTSPeriwinkle leaf extract significantly increased p53 protein expression (p<0.05) at both treatment doses, ½ IC50 and IC50, compared to the control group and it highly significantly reduced telomerase expression (p<0.01), in comparison with the control group at both treatment doses. CONCLUSIONPeriwinkle leaf extract has potential as an anti-breast cancer agent by increasing p53 protein expression and inhibiting telomerase expression.
Curcumin inhibits luteal cell steroidogenesis by suppression of extracellular signal regulated kinase Endang Purwaningsih; Sri Kadarsih Soejono; Djaswadi Dasuki; Edy Meiyanto
Universa Medicina Vol. 31 No. 2 (2012)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2012.v31.73-80

Abstract

BackgroundCurcumin inhibits steroidogenesis in luteal cell cultures by inhibiting progesterone secretion. The site of action of curcumin on steroidogenesis in luteal cell cultures is as yet unkown. The purpose of this study was to determine the influence of curcumin on phosphorylation of extracellular signal regulated kinase (ERK) in steroidogenesis of luteal cell cultures.     Methods An experimental study with control was conducted to investigate the site of action of curcumin by measurement of ERK phosphorylation in luteal cell cultures (LCC) after administration of luteinizing hormone (LH) and/or prostaglandin F2 alpha (PGF2á). The subjects of this study were luteal cell cultures derived from the corpus luteum of Sprague Dawley rat with superovulation induced by pregnant mare serum gonadotropin. The luteal cell cultures were devided into 16 groups, both with and without the addition of forskolin and each group contained 4 replicates samples. Curcumin was administered immediately following LH and/or PGF2á stimulation with or without addition of forskolin. The cell culture was then incubated for 24 h. ERK phosphorylation was measured by immunohistochemistry. Data on ERK phosphorylation was analyzed using one-way Anova, followed by multiple comparison tests.     ResultsLH significantly increased ERK phosphorylation, whereas PGF2á significantly reduced ERK phosphorylation. Forskolin significantly increased ERK phosphorylation to a similar degree as LH. Curcumin inhibited ERK phosphorylation in both LH and forskolin-stimulated luteal cell cultures. ConclusionCurcumin inhibits ERK phosphorylation in luteal cell cultures by suppressing signal transduction upstream of ERK.
GAMBARAN PENGETAHUAN MENGGOSOK GIGI PADA SISWA KELAS VIII SMP ISLAM AN-NAWAH DESA BATUKERBUY KECAMATAN PASEAN KABUPATEN PAMEKASAN Kinzoku Nur Alif; Endang Purwaningsih; Soesilaningtyas Soesilaningtyas
Jurnal Kesehatan Gigi dan Mulut (JKGM) Vol 3 No 2 (2021): Jurnal Kesehatan Gigi dan Mulut (JKGM)
Publisher : Jurusan Keperawatan Gigi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkgm.v3i2.821

Abstract

ABSTRAK GAMBARAN PENGETAHUAN MENGGOSOK GIGI PADA SISWA KELAS VIII SMP ISLAM AN-NAWAH DESA BATUKERBUY KECAMATAN PASEAN KABUPATEN PAMEKASAN Proporsi perilaku menggosok gigi setiap hari yaitu 94,7% dan 2,8% sudah menggosok gigi dua kali sehari, yakni pagi dan malam secara benar, upaya pemeliharaan kebersihan dan pencegahan penyakit gigi dan mulut yaitu dengan cara menghindari atau sekurang kurangnya memperkecil terjadinya pembentukan debris, plak dan kalkulus. Masalah penelitian ini adalah tingginya angka OHI-S pada siswa kelas VIII SMP Islam An-Nawah Desa Batukerbuy Kecamatan Pasean Kabupaten Pamekasan. Tujuan penelitian untuk mengetahui pengetahuan tentang menggosok gigi pada siswa kelas VIII SMP Islam An-Nawah Desa Batukerbuy Kecamatan Pasean Kabupaten Pamekasan. Jenis penelitian deskriptif dengan jumlah responden 30 siswa. Metode penelitian dengan pengisian lembar kuesioner. Teknik analisis data yang digunakan adalah dengan cara merekap hasil data yang telah dikumpulkan dan di sajikan dalam bentuk tabel. Hasil penelitian menunjukkan bahwa pengetahuan siswa tentang menggosok gigi dalam kategori buruk. Kata kunci : Gambaran Pengetahuan, OHI-S, Menggosok Gigi, Siswa. ABSTRACT DESCRIPTION OF THE KNOWLEDGE OF BRUSHING TOOTH IN CLASS VIII STUDENTS OF AN-NAWAH ISLAMIC SMP, BATUKERBUY VILLAGE, PASEAN DISTRICT PAMEKASAN The proportion of daily brushing behavior is 94.7% and 2.8% have brushed their teeth twice a day, namely in the morning and evening correctly, efforts to maintain cleanliness and prevent dental and oral diseases are by avoiding or at least minimizing the occurrence of debris formation. , plaque and calculus. The problem of this research is the high number of OHI-S in class VIII students of SMP Islam An-Nawah, Batukerbuy Village, Pasean District, Pamekasan Regency. The purpose of the study was to determine the knowledge about brushing teeth in eighth grade students of SMP Islam An-Nawah, Batukerbuy Village, Pasean District, Pamekasan Regency. Types of research is descriptive with the number of respondents 30 students. The method is by filling out a questionnaire sheet. The analysis technique used is to recap the results of the data that has been collected and presented in tabular form The results showed that students' knowledge about brushing their teeth was in the bad category. Keywords: Knowledge Description, OHI-S, Brushing Teeth, Students.
SYSTEMATIC LITERATURE REVIEW: PEMELIHARAAN KESEHATAN GIGI DAN MULUT PENYANDANG DOWN SYNDROME DITINJAU DARI PERAN ORANG TUA Tasya Olivia Natania; Ratih Larasati; Endang Purwaningsih
Jurnal Kesehatan Gigi dan Mulut (JKGM) Vol 3 No 2 (2021): Jurnal Kesehatan Gigi dan Mulut (JKGM)
Publisher : Jurusan Keperawatan Gigi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkgm.v3i2.909

Abstract

ABSTRAK Latar Belakang: Secara global penyandang disabilitas menujukkan lebih dari 1 miliar atau 15% jiwa sedangkan data Susenas 2018 penduduk Indonesia mengalami disabilitas 14,2% atau 30,38 juta jiwa. Penyandang disabilitas menunjukkan kesehatan yang buruk, prestasi pendidikan yang rendah, pendapatan ekonomi lebih sedikit dan tingkat kemiskinan lebih tinggi. Masalah kesehatan gigi dan mulut yang dialami para penyandang disabilitas seperti karies, maloklusi, gigi tanggal, penyakit periodontal. Tujuan: menjelaskan peran orang tua mengenai pelayanan pemeliharaan kesehatan gigi dan mulut, pelatihan dan pendampingan hidup mandiri, bersosialisasi dan berinteraksi tanpa rasa takut pada orang-orang Down Syndrome melalui ulasan artikel. Metode: penelitian ini merupakan tinjauan literatur sistematis dengan literatur pencarian selama 1 bulan. Literatur diperoleh dari 4 database ( Google Schoolar, PubMed, ProQuest, dan Science Direct ). Jumlah artikel 10 tahun terbit minimal 2016. Hasil: masalah periodontal dan maloklusi orang Down Syndrome serta OHIS yang buruk disebabkan masalah fungsional. Angka DMFT lebih rendah dari disabilitas lainnya. Orang tua berperan membantu dan menjaga kesehatan gigi dan mulut orang Down Syndrome , namun mereka tidak mengetahui perubahan kondisi rongga mulut anak mereka alami karena kurangnya pengetahuan dan pemahaman tentang kesehatan gigi dan mulut. Kesimpulan: perubahan fungsional orang Down Syndrome menyebabkan masalah gigi dan mulut karena kurangnya program promotif preventif serta ketersediaan akses pelayanan kesehatan, sehingga orang tua tidak mengetahui cara pemeliharaannya dan menganggap kesehatan dan mulut bukan prioritas dan jauh dari mengancam jiwa. Kata kunci : Peran orang tua, kesehatan gigi dan mulut, down syndrome
PENGETAHUAN HAK KEKAYAAN INTELEKTUAL (HKI) DOSEN DALAM UPAYA MENINGKATKAN KESADARAN BER-HKI CIVITAS ACADEMICA Derta .; Endang Purwaningsih
Jurnal Surya Kencana Dua : Dinamika Masalah Hukum dan Keadilan Vol 3, No 2 (2016): Jurnal Surya Kencana Dua: Dinamika Masalah Hukum & Keadilan
Publisher : Universitas Pamulang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (964.109 KB) | DOI: 10.32493/SKD.v3i2.y2017.516

Abstract

All members of academia—lecturers and students—who are the front liners in developing science and technology should be sufficiently equipped with the know-how on intellectual property rights (IPR), not only the ones related to patent rights but also those related to industrial design rights. This knowledge is crucial in helping all academia members to grow respect for copyrights. Since it is the academia members who produce intellectual work, the lecturers at YARSI University should be educated on the matter. And, as preliminary measures, research to map this issue at YARSI University is necessary. This research is applied normative/empirical normative/empirical juridical, that is, it stresses on the secondary data in analyzing the principles in positive laws and in analyzing factors which are related to the research object,  and analyzing its implementation in promoting intellectual property rights among lecturers. The mapping findings of this research conducted at YARSI University with 50 full-time respondents suggest that: the majority (64%) comprehends the issue while 36% others don’t; most lecturers (66%) cannot differentiate copyright from patent right while the other 34% can; some (30%) of the respondents can categorize intellectual rights (trademark, design, PVT, trade secrets) while 70% others cannot; most lecturers (62%) are informed of plagiarism and its related laws while 38% others are not; 52% of the lecturers cannot differentiate such terms as creator, copyright, inventor, and invention while 48% others can; 96% of the respondents are not aware of automatic protection while 8% others are; 96% of the respondents are not informed of the object of copyright and its scope as described in the latest law (UU No.28 2014) while the other 4% are; 58% of the respondents are clueless on outright sale, royalty, and license while 42% others are not; 80% of the respondents know whether or not it is allowed to have a book copied for personal purposes while the other 20% don’t; it is a relief to learn that 86% of the respondents are aware of the importance of having an invention listed although 14% others are not; most lecturers (60%) cannot differentiate such terms as ‘listed’, ‘registered’, and ‘published’, while 40% others can; all respondents (100%) do not know anything about copyright-related offenses which can be filed to court. Some measures taken to promote awareness of intellectual property rights among lecturers at YARSI University are education on the issue and reward for it in the form of incentives for performing lecturers with scientific publications and registered patents. At YARSI University, it is Deputy Rector II ex-officio Research Head who has the authority and plays the role in motivating the lecturers to conduct research and to earn intellectual property rights.Keywords: lecturers’ knowledge on IPR, awareness of IPR, academia
Pengembangan M-UKBM Gerak Melingkar Beraturan (GMB) Berbasis PBL untuk Meningkatkan Kemampuan Pemecahan Masalah Siswa SMA Vina Kuswatun Azizah; Endang Purwaningsih; Edi Supriana
Jurnal Riset Pendidikan Fisika Vol 4, No 1 (2019): Mei
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (704.355 KB) | DOI: 10.17977/um058v4i1p48-58

Abstract

Tujuan penelitian dan pengembangan ini adalah mengembangkan, mengetahui kelayakan, mengetahui kepraktisan, dan mengetahui keefektifan Mobile Unit Kegiatan Belajar Mandiri (M-UKBM) Gerak Melingkar Beraturan (GMB) berbasis Problem Based Learning (PBL) untuk meningkatkan kemampuan pemecahan masalah. Rancangan penelitian ini menggunakan model ADDIE yang terdiri dari lima langkah: analysis (analisis), design (mendesain), development (mengembangkan), implementation (melaksanakan), evaluation (menilai). Hasil penelitian menunjukkan bahwa M-UKBM yang dikembangkan termasuk layak dengan nilai rata-rata dari validator sebesar 3,76 dan termasuk praktis dengan nilai rata-rata keterlaksanaan pembelajaran dari observer sebesar 96,88%, selain itu M-UKBM efektif dengan dapat meningkatkan kemampuan pemecahan masalah siswa dengan nilai rata-rata peningkatan gain-score siswa sebesar 0,46 yang termasuk dalam kategori peningkatan sedang. Keefektifan M-UKBM diperkuat dengan nilai effect size sebesar 3,14 yang berarti keterpengaruhan M-UKBM terhadap kemampuan pemecahan masalah sangat kuat.
Peningkatan Penguasaan Konsep Siswa pada Materi Hukum Newton melalui Model Learning Cycle 7E dalam Kerangka PCK Dinda Taruna Nagara; Endang Purwaningsih; Markus Diantoro
Jurnal Riset Pendidikan Fisika Vol 6, No 1 (2021): Mei
Publisher : Universitas Negeri Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17977/um058v6i1p27-36

Abstract

Tujuan dari penelitian ini adalah mengembangkan bahan ajar fisika dengan model learning cycle 7E terintegerasi PCK pada materi hukum Newton yang layak, praktis, dan efektif untuk meningkatkan keterampilan proses sains dan pemahaman konseptual siswa. Penelitian ini menerapkan rancangan model 4D (define, design, develop, dan disseminate). Hasil uji coba kelompok kecil diperoleh persentase kelayakan sebesar 86,26% (sangat baik). Dengan demikian bahan ajar PCK learning cycle 7E layak untuk digunakan dalam pembelajaran. Hasil nilai observasi keterlaksanaan pembelajaran diperoleh persentase sebesar 93,27% (sangat praktis). Hasil uji Mann-Whitney pada nilai posttest kelas kontrol diperoleh nilai Asymp. Sig sebesar 0,250 dan kelas eksperimen nilai Asymp. Sig sebesar 0,024. Hasil analisis uji Mann-Whitney memberikan informasi bahwa terdapat perbedaan nilai Asymp.Sig kelas eksperimen lebih besar daripada kelas kontrol. Beradasarkan hasil analisis uji Mann-Whitney dapat disimpulkan bahwa bahan ajar fisika efektif untuk meningkatkan kemampuan penguasaan konsep siswa. 
Hubungan Obesitas pada Pra Lansia dengan Kejadian Hipertensi di Kecamatan Senen Jakarta Pusat Tahun 2017-2018 Juwita Kartika; Endang Purwaningsih
Jurnal Kedokteran dan Kesehatan Vol 16, No 1 (2020): JURNAL KEDOKTERAN DAN KESEHATAN
Publisher : Faculty of Public Health, Faculty of Medicine and Health, Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (387.326 KB) | DOI: 10.24853/jkk.16.1.35-40

Abstract

Hipertensi merupakan masalah kesehatan global termasuk Indonesia. Prevalensi hipertensi akan meningkat dengan bertambahnya usia. Hipertensi mempunyai berbagai macam faktor risiko dimana salah satunya adalah obesitas. Pemeriksaan yang digunakan dalam menentukan obesitas adalah indeks massa tubuh. Tujuan penelitian adalah mengetahui hubungan obesitas pada pra lansia dengan kejadian hipertensi di Kecamatan Senen Jakarta Pusat Tahun 2017-2018 dan tinjauannya dari sisi Islam. Penelitian ini dilakukan dengan pendekatan survey analitik secara cross sectional. Jumlah sampel penelitian 100 subjek dan pengambilan sampel dengan teknik cluster sampling. Pengukuran yaitu tekanan darah sistolik dan diastolik, tinggi badan, dan berat badan. Analisis data dilakukan dengan uji Chi-square. Hasil penelitian menunjukkan angka kejadian hipertensi pada pra lansia adalah 65 orang (65%) dan terdapat hubungan yang bermakna antara obesitas pada pralansia dengan kejadian hipertensi (p=0,029, OR=2,53). Disimpulkan bahwa obesitas berhubungan dengan kejadian hipertensi pada pra lansia dengan risiko 2,53 kali lebih besar dibandingkan dengan tidak obesitas.
Cytotoxicity Effects of Vitamin C on Cancer Cells MCF-7 Endang Purwaningsih; Samsul Mustofa; Pendrianto
Nusantara Science and Technology Proceedings Join Proceeding "Basic and Applied Science Conference (BASC) 2021 & 1st Education Research and Appli
Publisher : Future Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/nstp.2021.1103

Abstract

Vitamin C (ascorbic acid) is a powerful antioxidant that can reduce the effects of oxidative stress. One of the diseases caused by oxidative stress is cancer. The study aimed to assess the cytotoxic effect of vitamin C on MCF7 cancer cell cultures. This study used an in vitro laboratory experiment using MCF-7 breast cancer cell culture. MTS assay method was used to test the dose variance of vitamin C (l-ascorbic acid) against MCF-7 cultures. The MTS test used the CellTiter 96 Aqueous One Solution Cell Proliferation Assay kit. After that, 24 and 48 hours of culture were observed using test doses, 0 (negative control, K(–)), 10, 20, 40, 80, 160, 320 g/mL. The results showed the higher the dose given, the lower the viability of MCF7 cells, both at 24 and 48 hours of incubation. The lowest viability was obtained at 86.75% at a dose of 320 g/mL during incubation for 24 hours and 7.95% at a dose of 320 g/mL during incubation for 48 hours. In conclusion, vitamin C has a cytotoxic effect on MCF-7 cell culture with an IC50 value of 140 g/mL. Further research is needed to determine the effectiveness of vitamin C on the expression of the telomerase enzyme in breast cancer cells, especially MCF-7.
PARASIT PADA TIKUS RUMAH DI PEMUKlMAN KODYA BOGOR Endang Purwaningsih; H B Munaf; Sri Hartini
ZOO INDONESIA No 16 (1992): Zoo Indonesia No 16
Publisher : Masyarakat Zoologi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52508/zi.v0i16.2403

Abstract

Abstrak
Co-Authors . Deni . Mustaqim . Nopianti, . A.A. Ketut Agung Cahyawan W AA Sudharmawan, AA Abdul Kholiq Achmad Saim Achmadi Achmadi Achmadi Achmadi Adlika, Nur Meily Afrizal Afrizal Agil, Achmad Said Agus Hernudin Agus Suyudi Agus Wiwit Suwanto Ahmad Rusdan H Utomo Ahmad Taufiq Aini, Aisya Syarifa Aisyah Joyita Patria Ajeng Destian Suparwi Alghofiqi, Rizqi Ali Ma’sum, Ali Ma’sum Aminuyati andi hermawan Andina Nurul Wahidah Andriani, Wiwiek Retti Angga Rahabistara Sumadji Aniek Prihatin Annisa Ulfa Yana Antonius Antonius Antonius Totok Priyadi Apriliya, Thiara Sati Arif Hidayat Ariska, Vera Asrori , Asrori Astrini Dewi Kusumawati Astuti Giantini Azriel Al Mushorih B. Anggit Wicaksono, B. Anggit Babay, Babay Baderan, Yesika Adhisdea Bambang Genjik Bambang Genjik Sumartono Basrowi Basrowi Basrowi, Basrowi Ba’abduh, Assyfa Husni Benny Batubara Berliana Effrianti BUDIARTI, IYOK Budilaksono, Sularso Budiyanto Budiyanto Catur Wulandari Cecep Sukrisna Chandra Yusuf Chatarina Umbul Wahyuni Christianto Adhy Nugroho Cindy Tri Putri Damayanti, Sherly Eka Putri Darmawan, Alif Dedik Iwan Setiawan Dedy Haryanto Deny Sujana Miharja Derallah A Lindra Deriliana, Yosephine Derta . Derta Rahmanto Dewantara, Jagad Aditya Dewi Ikhfina Karima Dewi Kusumaningsih Dian Ayubi Dian Mardhiyah Dian Purnamasari Dianningrum, Magfira Cindy Dinda Taruna Nagara Diniwati Mukhtar Diniwati Mukhtar Diniwati Mukhtar Djaswadi Dasuki Djaswadi Dasuki Dwikoranto Edy Meiyanto Edy Meiyanto Eka Putri, Nur Yasfin Eka Sopianida, Eka Eko Poerwanto Eko setiawan Elis Ratna Dewi Endah purnamasari Endy Muhammad Astiwara Eny Latifah, Eny Esi, . Ester Ester Etty Widayanti Etty Widayanti Etty Widayanti Etty Widayanti Etty Widayanti Etty Widayanti, Etty Evie Rachmawati Nur Ariyanti Faisal Yunus Faisal Yunus Fanni Yuniar Fatah Kurniawan, Fatah Fathur Rizqy Fathurahman, Muhamad Febi Putri Fiky Niswati Yuslihah Firman Arifandi Gadis Dari Adn Ghasani, Almas Sabrina H B Munaf H B Munaf, H B Hadi Wiyono Hafid Ernanda Hafidz Putra Herlyansyah Hafifah Hafifah Handoyo Saputro Harahap, Makrup E Haritzah, Tan Zhauna Hafis Hartanto, Agung Eko Hawasi Hawasi, Hawasi Heaven Erisa, Heaven Helwiyah Umniyati Hendrawati, Gandes Widya Hendro Firmawan Heni Kuswanti Herika Hayurani Herkulana . Herkulana Herkulana Heru Wiratmoko Hijriana, Ihda Holy Ametati Husni Syahrudin I Gusti Ayu Ketut Rahmi, I Gusti Ayu I Putu Yogi Setia Permana Ika Rahmatika Chalimi Indra Kusuma Irfan Islami, Irfan Irfan, Muhammad Rifai Irwan Santosa Isnanto Isnanto Isnanto Isnanto Iwan Ramadhan Iwan Setiawan, Dedik Jarot Tri Bowo Santoso Jasir Hakim Joko Utomo Jumardi Budiman Junaidi H. Matsum Junaidi H.Matsum Juwita Kartika Kadarsih Soejono, Sri Kadarsih Soejono, Sri Karlina, Selfi Kartika Dewi Kholis Ernawati Kinzoku Nur Alif Krisna Yetti Kurnia, Kessy Kurniawan, Bakhrul Rizky Kuslestari Laras, Laras Larasati, Isti Andini Larasati, Ratih Leo Eladisa Ganjari Lia Yuliati, Lia Lily Endang Setyorini, Lily Endang Lindra, Derallah A Lismayanti, Erna M. Fadli Ramdani, M. Fadli M. Rafly Afrizal Pratama Maghfiroh, Alifiyah Nindi Maharianti, Ratri Maimunah Maimunah Maisyarah, Rahmah Mandai, Doris Maradoni, Sandro Marcella Linda Indriani Maria Desinta Maria Ulfah Marisa Riliani Mariska Mariska, Mariska Marjianto, Agus Markus Diantoro Martha Irene Kartasurya Martha Riskiaty Mashudi , Mashudi Mashudi Miftahuljannah Muslimin Mirfat Mirfat Moh. Rezqi Maulidhani Mohammad Ryan Bakry Mohammad Z. Rahfiludin Mubyaring Putri Sayekti, Azzahra Muhammad Basri Muhammad Samsul Mustofa Munasir Murjani Murjani Muslikh Muslikh Myron Shekelle, Myron Nabilla Rizqina Rachmaputri Nasir, Nur Indah Ririn Fitriani Nelly Ulfah A.R., Nelly Nelly Ulfah Anisariza Nenden Lilis Ngusmanto, - Nugraha, Farel Fathin Nunung Ainur Rahmah Nuraini Asriati Nuril Munfaridah, Nuril Nurizza, Efa Nurjanah, Ifah Nurul Aprilia, Nurul Nurul Huda Octavia, Nataya Rizka Okianna . Okianna Okianna Ozara, Hana P Purwanto P. Laksono, Sony Padillah, Evi Nur Pantiana, Resa Parijo Parijo Parno Parno Parno Pendrianto Pendrianto Pendrianto Praptama, Sandhi Setya Prasetyowati, Silvia Pratami, Ayu Venty Priyonggo, Rizky Yuwono Joko Purbo Suwasono Purnama, Shilmy Purnomo Purnomo Purwaningsih, Yustina Putra Perdana Putri, Desi Eka Putri, Febi Putri, Febi Dwi Qomariyah Qomariyah Qomariyah Qomariyah Qomariyah Qomariyah Qurratul Ain Ragan Varian Antariksa Rahayu, Rusiana Rahma Safitri Rahmawan, Grandis Ramadani, Cahyani Intan Ramadhan, Muhammad Satrio Ratna Dewi Ratna Dewi, Elis Ratna Ekawati Ratna Sukowati Reqgi First Trasia Reqgi First Trasia Retno Ningsih, Tri Wahyu Revnika Faizah Reyza Arief Taqwa, Muhammad Riliani, Marisa Rio Griya Putra Riri Mela Lomika Siregar Riselligia Caninsti Rita Sutjiati Riyanto, Awal Riyanto, Awal robbi, dzikri robbi Rogo Subandono Rum Rosyid Rustiyarso . Safitri, Anindyta Nur Rizkyana Salim, Nabila Salsa, Dini Samsul Mustofa Samsul Mustofa Samsul Mustofa Samsul Mustofa Samsul Mustofa, Muhammad Sandhi Setya Praptama Santosa, Irwan Septarini, Ridhotin Alwiyana Septia, Septia Setialin, Ananda Nida Setiyoaji, Wahyudha Tri Shintya Nabilla Trianti Silvi Ayu Dewi Mashito Simaremare, Rointan Siti Helmyati Siti Jamilah Soesilaningtyas, Soesilaningtyas Sofwan, Achmad Sri A. Nugraheni Sri Buwono . Sri Hartika Sri Hartini Sri Hartini Sri Hidayati Sri Kadarsih Soejono Sri Mulyati Sri Muryati Sri Wahyu Herlinawati Sri Wahyu Herlinawati Sri Wahyu Herlinawati Sri Wahyuni Sri Wahyuni Sri Wahyuni Wulandari, Sri Wahyuni Sugeng Praptomo,, Sugeng SUGIYANTO Suhaeri Suhaeri, Suhaeri Sulistyarini, Sulistyarini Sunarti Sunarti Sunaryono Sunaryono, Sunaryono Sunomo Hadi Supriana, Edi Susanti, Shinta Dewi Suwanto, Agus Wiwit Suwasono, Heru Suwitho, Suwitho Tasya Olivia Natania Taufiq, Briliantama Akbar Thomy Sastra Atmaja Titiek Djannatun TITIEK DJANNATUN Tjandra Yoga Aditama Tomo Djudin Tri Wahyu Retno Ningsih Tussa Balsia, Monik Nomi Ulfah, Siti Fitria Umamei, Haritsa Utomo, Ahmad Rusdan H Ventayen, Randy Joy Magno Vina Kuswatun Azizah Wardani, Dwisri Warneri . Wigati Pujiastuti Wiratmoko, Heru Witari, Endang Sri Witarsa Witarsa, Witarsa Wulandari, Ika Pratiwi Yambi, Tomás de Aquino Caluyua Yanto, Heri Apri yarso, Meilany Yenni Zulhamidah, Yenni Yolanda Dwi Vivian Karawahenni YULIA AMANATI, ANIS Yulia Suciati Yulia Suciati Yusuf, Chandra