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Journal : Jurnal Ilmu dan Teknologi Kayu Tropis

Sifat Antirayap Resin Damar Mata Kucing dari Shorea javanica K. et V. Antitermic Properties of Resin from Shorea javanica K. et V Rita Kartika Sari; Wasrin Syafii; Kurnia Sofyan; Muhammad Hanafi
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 2, No 1 (2004): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (245.077 KB) | DOI: 10.51850/jitkt.v2i1.314

Abstract

This study was undertaken primarily to isolate and identify substances from resin of Shorea javanica K. et. V. that might be responsible to inhibit the termite activity of Coptotermes curvignathus Holmgren. Approximately 500 gram of dried-resin was extracted with acetone solvent. The acetone extract was then fractionated into n-hexane, diethyl ether, ethyl acetate, and insoluble fraction (residue). The no-choice bioassay test was carried-out by treating paper discs with extracts at  the concentration of  2.0%, 4.0%, 6.0%, 8.0%, 10.0%, 12.0% (W/W), and 0.0 % as control. The bioassay test showed that n-hexane and diethyl ether soluble fraction exhibited highest antitermic properties at Lethal Concentration (LC)50 value of 1.62% and continuation fraction showed N3 of n-hexane fraction an EE1 of diethyl ether fraction exhibited highest toxicity at LC50 value of 1.23 % and 1.65%. Further investigation of the n-hexane soluble fraction by using CC, GC-MS, FTIR, UV-Vis, and NMR led to the isolation and identification of the main compound, namely friedelin, while the diethyl ether soluble fraction contains vulgarol B; 3,4-Secodamar-4(28)-en-3-oic acid; (7R,10S)-2,6,10-Trimethyl-7, 10–epoxy-2,11-dodecadien; and junipene (decahydro-4,8,8-trimethyl-1,4-methanoazulene)
Chemical Composition and Anticancer Activity Of the Essential Oil Of Surian Heartwood Rita K Sari; Wasrin Syafii; Suminar S Achmadi; Muhammad Hanafi
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 9, No 2 (2011): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (476.853 KB) | DOI: 10.51850/jitkt.v9i2.140

Abstract

Chemical constituents of the essential oil of water and steam distillates of surian heartwood (Toona sinensis) were analyzed by a gas chromatograph-mass spectrometer. Then, the oil was investigated in vitro anticancer bioassay for its possible antioxidant activity by DPPH free radical scavenging and antiproliferative effects by MTT method using Raji lymphoma cancer cell lines (ATCC CCL 86), HeLa cervical cancer cell lines (ATCC CCL2), and Vero normal cell lines (ATCC CCL 81). The essential oil yield from water and steam distillates of surian heartwood was 0.4% (w/w). Thirty-two compounds were identified, that consisted mainly of oxygenated sesquiterpenes (77%). The most representative compounds were spathulenol (21%), isospathulenol (7%), α-cadinol (7%), β-cedrenoxide (6%), and torreyol (5%). The oil showed less effective antioxidant, but the oil had high antiproliferative effects on Raji and HeLa cancer cells with IC50 28 and 134 μg ml-1, respectively when compared to Vero normal cells (IC50 1412 μg ml-1). Our findings suggest that the essential oil of surian heartwood might be considered as a potentially anticancer agent on human cancer cells, especially lymphoma cancer cells.Key words: antioxidant activity, antiproliferative effects, cancer cell lines, essential oil, Toona sinensis
Sifat Anti Jamur Kayu Kupa (Syzygium polycephalum (Mig)) (Antifungal Properties of Kupa Wood (Syzygium polycephalum Mig.)) Renhart Jemi; Wasrin Syafii; Fauzi Febrianto; Muhammad Hanafi
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 8, No 2 (2010): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (579.91 KB) | DOI: 10.51850/jitkt.v8i2.214

Abstract

The objectives of this research were to evaluate the extractive substances of heartwood of Kupa wood (Syzygium polycephalum (Mig)) and its potention as bio-active substance to wood destroying fungi i.e., Schizophyllum commune Fr and Pleurotus sp. Successive extraction method was used in this experiment. The heartwood part was then converted into 40 mesh wood flour and followed by extraction using methanol, chloroform, ethyl acetate, n-hexane and buthanol solvents. The extractives obtained were subjected to wood destroying fungi S. commune and Pleurotus sp. The results indicated that the extractive content of S. polychephalum mostly dominated by substance diluted in chloroform (2.87%), followed by ethyl acetate (0.38%), n-hexane (0.33%) and buthanol (0.05%). All the wood extracts of S. polychephalum potentially contain anti-fungal compound to inhibit the growth of S. commune Fr and Pleurotus sp fungi. N-hexane and ethyl acetate extracts of S. polychephalum are the most active extracts. Isolation of ethyl acetate fraction resulted in nine (9) active compounds (G.1-G.9) that could inhibit the growth both S. commune and Pleurotus sp with IC(50) values 49.33-61.71 ppm and 48.84-64.61 ppm, respectively. It was found that G.2 compound of ethyl acetate has anti fungal substance namely 3-O-glucosyl-3’,4’ 5-trihydroxyflavonol.
Sifat Anti Jamur Kayu Kupa (Syzygium polycephalum (Mig)) (Antifungal Properties of Kupa Wood (Syzygium polycephalum Mig.)) Renhart Jemi; Wasrin Syafii; Fauzi Febrianto; Muhammad Hanafi
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 8, No 2 (2010): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (579.91 KB) | DOI: 10.51850/jitkt.v8i2.224

Abstract

The objectives of this research were to evaluate the extractive substances of heartwood of Kupa wood (Syzygium polycephalum (Mig)) and its potention as bio-active substance to wood destroying fungi i.e., Schizophyllum commune Fr and Pleurotus sp. Successive extraction method was used in this experiment. The heartwood part was then converted into 40 mesh wood flour and followed by extraction using methanol, chloroform, ethyl acetate, n-hexane and buthanol solvents. The extractives obtained were subjected to wood destroying fungi S. commune and Pleurotus sp. The results indicated that the extractive content of S. polychephalum mostly dominated by substance diluted in chloroform (2.87%), followed by ethyl acetate (0.38%), n-hexane (0.33%) and buthanol (0.05%). All the wood extracts of S. polychephalum potentially contain anti-fungal compound to inhibit the growth of S. commune Fr and Pleurotus sp fungi. N-hexane and ethyl acetate extracts of S. polychephalum are the most active extracts. Isolation of ethyl acetate fraction resulted in nine (9) active compounds (G.1-G.9) that could inhibit the growth both S. commune and Pleurotus sp with IC(50) values 49.33-61.71 ppm and 48.84-64.61 ppm, respectively. It was found that G.2 compound of ethyl acetate has anti fungal substance namely 3-O-glucosyl-3’,4’ 5-trihydroxyflavonol.
Antifungal Properties of Palepek Baringin Wood (Shorea leavis Ridl) Renhart Jemi; Wasrin Syafii; Fauzi Febrianto; Muhammad Hanafi
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 10, No 1 (2012): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.068 KB) | DOI: 10.51850/jitkt.v10i1.124

Abstract

The objectives of this research were to evaluate the extractive substances of heartwood of palepek baringin wood (Shorea leavis Ridl) as a bio-active substance to wood destroying fungi i.e. Schizophyllum commune Fr and Pleurotus ostreatus. The 40 mesh of heartwood meals was extracted by methanol, chloroform, ethyl acetate, n-hexane and buthanol. The extractives obtained were subjected to wood destroying fungi S. commune and P. ostreatus, and preservative containing copper, chrome and boron (CCB) was used for comparison. The extractive of palepek baringin wood was dominated by ethylacetate fraction (3.54%), followed by chloroform and butanol fraction 1.73% and n-hexane (0.09%). All fractions have an antifungal activity to inhibit the growth of S. commune and P. ostreatus. Concentration of 50 ppm butanol fraction inhibited the growth of S. commune, and concentration of 250 ppm chloroform fraction inhited the growth of Pleurotus sp. Preservative of CCB 100 ppm inhibited the growth of S. commune and P. ostreatus by 43%. Butanol fraction contained 16 active compounds (PB.1-PB.16) that could inhibit the growth both of S. commune and P. ostreatus with IC50 54.29-64.32 and 48.40-65.86 ppm, respectively. Based on mass spectrometry (LC-MS) and 1HNMR analysis, the compound of PB.1.1 which has anti-fungal activity was 2,3-dihydroxyoctadecanoic acid.Key words: 2,3-dihydroxyoctadecanoic acid, antifungal, Pleurotus ostreatus, Schyzophlum commune, Shorea leavis
Anticancer Activity and Chemical Compounds of Suren Heartwood Extract (Toona sureni) Rita K Sari; Wasrin Syafii; Suminar A Achmadi; Muhammad Hanafi; Yanotama T Laksana
Jurnal Ilmu dan Teknologi Kayu Tropis Vol 10, No 1 (2012): Jurnal Ilmu dan Teknologi Kayu Tropis
Publisher : Masyarakat Peneliti Kayu Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (400.145 KB) | DOI: 10.51850/jitkt.v10i1.120

Abstract

The aims of this research were to determine the yield extracts from continuous extraction of suren heatwood (Toona sureni) in n-hexane, ethyl acetate and methanol solvents, to evaluate this extracts using in vitro anticancer tests (antioxidant, brine shrimp lethality test /BSLT, antiproliferative effects to HeLa servical cancer cell lines, Raji limphoma cancer cell lines, and Vero normal cell lines), and to analyze the best extract based on the anticancer activities. This experiment showed that the yield of methanolic, ethyl acetate, and n-hexane extracts were 0.43%, 0.25%, and 0.18% respectively. The methanolic and ethyl acetate extracts had the high antioxidant activities with EC50 51 and 68 μg ml-1 respectively. Based on BSLT, the ethyl acetate extract was the most active extract (LC50 40 μg ml-1), it followed by the methanolic extract (LC50 116 68 μg ml-1 ), and the n-hexane extract (LC50 161 68 μg ml-1). Further testing showed that the ethyl acetate extract had high antiproliferative effects to Raji (IC50 31 μg ml-1) and HeLa (IC50 65 μg ml-1), but it was more secure against Vero cell lines (IC50 105 μg ml-1). Whereas compounds such as catechol, linalool, and sitosterol contributed to the high anticancer activities of this ethyl acetate extract.Key words: anticancer activity, HeLa cell lines, Raji cell lines, Toona sureni, Vero cell lines
Co-Authors . Hariyanti Abd Kahar Abdul Gani Abdul Mughni Ade Chandra Iwansyah Adipratiwi, Nadia Adnan, Andi Astina Afriza Media Ahmad Ramadani, Ahmad Ahmad Shohibul Wafa Akhmad Darmawan Alaiddin Koto, Alaiddin Ali Karmani Almasri Alva Hendi Muhammad Amalia Amalia Ameliah, Nurul Andi Karman, Andi Andi Sadapotto Andini Sundowo Andri Eko Putra Anggraini, Febi Ansumarwaty, Febiyanti Apriandini, Lisya Apriani, Ari Aprilia, Jesika Wanda Ardiansyah, Febry Aries Sukariawan Aris Doyan Arisanto, Ahmad Budi Ariyani, Titin Armanda Putra, Mochammad Ravi asma, Rasma Asmawati, Talitha Raissa Asrifan, Andi Aswadi Aswadi Aswadi Asy'ari, Ahmad Hasyim Atiek Soemiati Atiek Sumiati Atmawinata, Maya R Aulia, Meilita Auliya, Isnie Azahra, Silena Azim, Nur Santriani Utari B. Suwandl Bagaskara, Bagaskara Berna Elya Buhari Buhari D Efrina Dadan Ridwanuloh Darwati Darwati Demastita, Ni Putu Fanty Desi Harneti Putri Huspa Desi Ramayanti Djamil, Ratna Dwi Astuti Ecca, Suleha Elidayani, Evi Ellyzena Wulandari Ema Utami Endang Saepudin, Endang Erma Ermawan Ermawan ERWAHYUNI ENDANG PRABANDARI Erwin, Muh Evawani Elysa Lubis Fadlina Chany Saputri Farabi, Kindi Farasalsabila, Fidya Fatimah Azzahrah Fatimatushshalichah, Syayidati Fatmawati Fatmawati Fatmawaty Fatmawaty Fatonah, Astri Amaliah Fauzi Febrianto Fauzi, Kevin Azhar Fauziah Nur Ariza Fenny Bintarawati Firma Hafmi Fitri Rahayu Fitrianingtyas, Rizki Galuh Widiyarti Gatot Yudoko Ghapur, Muhammad Abdul Ghazali, Fikri Ghofardhan, Muhammad Ghozali, Arinaa Sabilah Gunawan Gunawan Hajijah, Humairah Hakiki, Dina Hany, Iga Permata Hasan Hasan Hasan Hasan Hasanuddin Hasanuddin Hasibuan, Wildan Ansori Hasnaliah, Hasnaliah Hayu Dwimawanti, Ida Hendig Winarno Hendra Saputra Herry Cahyana Hidayat, Tegar Samudra Hizyam, Muhammad Huzaena, Mifta Idayanti Idayanti Idharul Haq Iis Irawatty Dewi Ika Mustika Ilhamuddin Ilhamuddin, Ilhamuddin Imam Fauji, Imam Intan Nurjaya Irwan Yon Hadi Jala, Jusrianto Jamaluddin Ahmad Jemi, Renhart Jumiati Jumiati Jumiati Junedi, M Irfan Jusrianto K, Nuraini K, Rahmana Emran Kahar, Kurnia Putri Kamal, Kamal Kardono, Broto Sugeng Kasau, M Nurzin Kasman, Nuraini Kasmiati Khairunnisa, Shofiyah Khalik, Suhartini Khalik, Suhartini Kindy S, Mhd Al Kurnia Sofyan Kurniati Kurniati Kusmardi Kusmardi L, Syahrir Lababa Lababa Ladeska, Vera LALU RUDYAT TELLY SAVALAS Landong, Ahmad Lanta, Jumiati Lilik Kustiyah Linayanti Linda Maryani Lotulung, Puspa Dewi N. M Nurzin K M, Usman M. Idris M. Nurzin R. Kasau Mahise Okten Ramadhani Mahmud, Nurlaelah Mailawati Mamoru Kanzaki Manda, Ibrahim maria ulpah Marshalina, Afifah Marzuki Marzuki Masnawati Mau’ud, Mohamad Megawati, Meliantari, Dian Mhd.Furqan Mierza, Vriezka Moch. Chasani Mohammad, Amrija Mudzakir Nur Hidayatussani Muh. Zahirul Haq Usman Muhamad Rizal Martua Damanik Muhammad Ihsan Muhammad Iksan, Muhammad Muhammad Nawir Muhammad Ridwan Muhammad Rizki Muhammad Zul Fahmi Muhammad, Firdaus Yusri Muhlis Mujib Ridwan Muliani Mulyana Mulyana Mulyani, Ridha Muntari Muntari Murdani, Elisa Musdalifa Basri Nada Saniyah Nadirah, Nadirah Nahdah, Khalilah Nurun Narrij Lotulung, Puspa Dewi Nasrullah Ngadiman Ngadiman Ngadiman Ngadiman Ni Luh Putu Pebri Artayani . Nia Aprilia Nina Artanti Nina Artanti Nindiyana, Baiq Nurmaulida NL, Puspa Dewi Nofrianto, Noke Norcahyono Norcahyono Nova Yohana Nur Asmah NUR FADILAH Nur Luthfi Hanif Al-Baihaqi Nur, Andi Herlina Nuraini K Nuraini Kasma Nurlaelah Mahmud Nurlelasari Nurlelasari Nurlia Arsyad Nurmala Nurmala Nurmala Nurmala Nurul Fadhilah Suardi Nurwahida Nurwahida, Nurwahida Nurwulan, Zulhilda Pandapotan Simbolon Pandiangan, Martina Pohan, Selamat Pramono, Sekardini Cahyaning Pramudito, Adrian Prastiwi, Mentari Dwi Puspa D.N Lotulung Rahayu, Karmila Dwi Rahmat Mulyana Dali Rahmayani, Mentari Tri Indah Rahutomo, Suroso Raja Joko Musridho Ramadhan, Dany Ramdhani, Eka Putri Cahya Rani Maharani Rasyid, Rustam Efendy Razali, Mariany Renhart Jemi Rifa’i Rika Oktavia Damayanti Rina Hidayati Pratiwi Riska Handayani Rita K Sari Rita Kartika Sari Rohmat, Siti Saudah Rony, Zahara Tussoleha Rosa Dewi Pratiwi Rosmalena Rosmalena Rosmini Kasman Rusmaliati, Rusmaliati Rusny Edy Rustam Efendi Ruswati, Ruswati Ryandi Safitri, Noraya Safni Marwa Saifullah Saifullah Saifullah Sailal Arimi Sainab Sakiah Sakiah Salahuddin Salahuddin Saleh, Firman Sam Hermansyah Sanati, Sanati Santy Rahmawati Saprizal Hadisaputra Sari, Riski Monno Sarifuddin Sarifuddin Sedijani , Prapti Senny Widyaningsih Septiasa, Alfia Muawanah Serli Sanggang Sarasta Shibata Kozo Silvia Fadila Siti Annisa Wahdiniawati, Siti Annisa Siti Isnijah Siti Sunariyati Siti Zulfa Sofa Fajriah Soleh Kosela Sri Karyati Sri Mursiti Suardi Zain, Suardi Subaidi, Mohammad Subhan Nooriansyah Sukranudin Suleha Suleha Ecca Suleha, Suleha Sulistiyowati, Arrin Suminar A Achmadi Suminar S Achmadi Suminar S Achmadi Syahrir L Syahrul Aiman Syamsu T Syamsul Bahri Syamsur Rizal Syufina, Arina Shofia T, Syamsu Tati Herlina Teni Ernawati Tri Mayanti Tri Yuniningsih Ulpah, Kamaria Unang Supratman Undri Rastuti Uniawati Usman M Usniati, Ita Vinella Winata Vivitri Dewi Prasasty wahyuni wahyuni Waluyo, Danang Wasrin Syafii Yanotama T Laksana Yanti Fitria Yasir ", Yasir Yayuk Andayani Yesi Desmiaty, Yesi Yunni, Yunni Yusmah Yusmah Yusmah Yusmah, Yusmah Zozy Aneloi Noli Zubaedi, Umam Faqih Zulfahmi Zulfahmi