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NANOTOXICOLOGY AND BIOINTERACTION ASSESSMENT OF BIOMEDICAL NANOMATERIALS Ivan Dimitrov; Maria Ivanova; Muntasir Muntasir
Journal of Biomedical and Techno Nanomaterials Vol. 3 No. 3 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v3i3.3962

Abstract

Biomedical nanomaterials have garnered significant attention for their potential applications in medical diagnostics, drug delivery, and therapeutic interventions. However, concerns regarding their toxicity and biointeraction with biological systems remain largely unaddressed. Understanding the safety and biological interactions of these materials is crucial for ensuring their efficacy and safety in clinical settings. The aim of this study was to assess the nanotoxicological properties of biomedical nanomaterials and their interactions with biological systems. The research focused on evaluating the cytotoxicity, genotoxicity, and immunotoxicity of various nanomaterials commonly used in biomedical applications. A combination of in vitro and in vivo assays was employed to assess the toxicological profile of biomedical nanomaterials. These included cell viability tests, oxidative stress analysis, DNA damage assays, and immune response evaluations. The interactions between nanomaterials and cellular components were also examined using advanced imaging and spectroscopy techniques. The findings indicated that the toxicity of nanomaterials varied depending on their size, surface charge, and composition. Certain nanomaterials demonstrated significant cytotoxic and genotoxic effects, while others showed minimal toxicity. The biointeractions were also influenced by the concentration and exposure duration. The study underscores the need for comprehensive toxicity assessments of biomedical nanomaterials to ensure their safe application in medical technologies. Further research is required to optimize their safety profiles for clinical use.
Risk Factors of Pneumonia in Children under Five in Lewoleba Hospital, East Nusa Tenggara, Indonesia Nikosius Dae Sory Wutun; M Dinah Charlota Lerik; Muntasir Muntasir
Journal of Epidemiology and Public Health Vol. 5 No. 2 (2020)
Publisher : Masters Program in Public Health

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (30.892 KB)

Abstract

Background: Pneumonia is an infection of the res
Effectiveness of Lavender (Lavandula angustifolia) and Jasmine (Jasminum officinale) Aromatherapy on the Intensity of Dysmenorrhea in Student of Faculty of Public Health, Universitas Nusa Cendana, Kupang Maria Antonia Nurak; M. Dinah Charlota Lerik; Paula Tibuludji; Muntasir Muntasir; Refli Refli
Journal of Maternal and Child Health Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.236 KB)

Abstract

Background: Dysmenorrhea is a menstrual cramp that in general occurs in adolescents. In In
Profil Mutu Karagenan Kappaphycus alvarezii asal Pulau Semau pada Pengeringan Oven dan Sinar Matahari Berdasarkan Analisis Kadar Air dan Kandungan Karagenan Chatrin Lenggu; Muntasir Muntasir; Mathias N. Kolobani
JURNAL FARMASI DAN MAKANAN Vol 9 No 2 (2026): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v9i2.8348

Abstract

Kappaphycus alvarezii is the primary source of carrageenan widely utilized in pharmaceutical, food, and cosmetic industries. Carrageenan quality is significantly influenced by post-harvest drying methods. This study aimed to analyze effect of drying methods on moisture content and carrageenan content of red variety K. alvarezii from Letbaun Village, Semau Island, East Nusa Tenggara. A quantitative descriptive design was applied using two treatments: natural sun drying for ±3 days and oven drying at 60°C for 48 hours. Moisture content was determined by gravimetric method, while carrageenan content was quantified using High Performance Liquid Chromatography (HPLC) after alkaline extraction with 8% KOH. Statistical analyses were performed using Shapiro–Wilk test, Levene's test, and independent sample t-test (α = 0.05). Oven drying yielded a moisture content of 27.32% and a mean carrageenan content of 25.98%, whereas sun drying yielded 28.85% moisture and 24.13% mean carrageenan. Both methods complied with SNI 2690:2015 standards (≤ 30%). The independent t-test indicated no statistically significant difference between two methods (p = 0.471; p > 0.05), although oven drying numerically produced higher carrageenan content. Oven drying is recommended as a more controlled and consistent post-harvest alternative for producing high-quality carrageenan raw materials for pharmaceutical applications.
One Health Approach to Environmental and Public Health Challenges: Bridging the Gap between Human, Animal, and Environmental Health Benny Novico Zani; Jackson Lee; Muntasir Muntasir
Journal of Multidisciplinary Sustainability Asean Vol. 3 No. 3 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/ijmsa.v3i3.3450

Abstract

Background. This study is grounded in the growing recognition that complex environmental and public health challenges cannot be effectively addressed through sectoral approaches that separate human, animal, and environmental health. Accelerating climate change, biodiversity loss, emerging zoonotic diseases, and environmental degradation have intensified interactions across these domains, revealing critical weaknesses in fragmented health governance. Purpose. The objective of this research is to examine how the One Health approach can serve as an integrated framework to bridge disciplinary and institutional gaps in addressing contemporary environmental and public health challenges. Method. The study employs a qualitative integrative review design, synthesizing evidence from peer-reviewed international journals, policy reports, and global health frameworks to identify patterns, mechanisms, and implementation strategies associated with One Health practices. Results. The findings indicate that One Health-oriented interventions enhance early disease detection, improve risk communication, strengthen environmental monitoring, and support more resilient public health responses through cross-sector collaboration. The results also demonstrate that institutional coordination, data integration, and shared governance structures are decisive factors in translating One Health principles into measurable health outcomes. Conclusion. The study concludes that the One Health approach represents a transformative paradigm for public and environmental health governance, offering a robust pathway to manage systemic risks at the human–animal–environment interface. Strengthening policy alignment, interdisciplinary capacity, and institutional commitment is essential to realize its full potential.
Determinant Factors of COVID-19 Vaccination Participation at Ndetundora Health Center, Ende, East Nusa Tenggara Hafaf Lutfiani Sani; Muntasir; Tadeus A. L. Regaletha
Journal of Health Promotion and Behavior Vol. 8 No. 3 (2023)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejhpb.2023.08.03.05

Abstract

Background: The COVID-19 pandemic is one of the major public health problems today and the whole country is experiencing a pandemic. Vaccination is the government's effort to tackle the COVID-19 pandemic. The coverage of COVID-19 vaccination at the Ndetundora Health Center in 2021 is still low, namely as much as 14.80% for dose 1 and 7.04% for dose 2, then in 2022 the vaccination coverage will increase quite high, namely 75.16% for dose 1 and 53.23% for dose 2. The purpose of this study was to find out the public's interest in taking the COVID-19 vaccination in the working area of the Ndetundora Health Center, Ende Regency in 2022. Subjects and Method: A cross-sectional study was conducted at the Ndetun­dora Health Center, Ende, East Nusa Tenggara, from September to October 2022. A total of 243 people were selected for this study. The dependent variable was the public's interest in taking the COVID-19 vaccination. The independent variables are age, gender, education, occupation, knowledge, attitude, community motivation and public communication. Data were collected using a questionnaire and analyzed using Chi-square. Results: The results showed that someone with higher education increased their interest in taking the COVID-19 vaccination by 0.38 times compared to people with low education, and the results were statistically significant (OR= 0.38; 95% CI= 0.21 to 0.69; p= 0.001). Someone with motivation High motivation increase interest in taking the COVID-19 vaccination by 49.5 times compared to those with low motivation (OR = 49.5; 9% CI = 21.49 to 114.16; p < 0.001), good public communication will increase public interest in taking the COVID-19 vaccination 2.74 times compared to poor public communication (OR= 2.74; 95% CI= 1.20 to 6.25; p= 0.014). Conclusion: Education, knowledge, attitudes, community motivation, and public communication have a significant effect on participation in the COVID-19 vaccination. Keywords: public interest, vaccination, COVID-19. Correspondence: Hafaf Luthfianti Sani. Study Program of Public Health, Faculty of Public Health, Universitas Nusa Cendana. Jl. Adisucipto, Penfui, Kupang, 85001, East Nusa Tenggara. Email:  hafafsani16­@­gmail.­com. Mobile: +62 821-4436-7462.
Inovasi Camilan Sehat Ikan Bandeng Tingkatkan Gizi Remaja Putri Pangkajene Sri Prilmayanti Awaluddin; Rustam Rustam; Andi ummul Khair; Indrawan Azis; Nurani Nurani; Muntasir Muntasir
Jurnal Abdimas Multidisiplin Vol 4 No 1 (2025): Oktober
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/jamu.v4i1.5269

Abstract

Purpose: This service aims to increase the knowledge and skills of young women in processing milkfish into healthy snacks that are appealing, thus promoting better nutritional intake and economic opportunities in Bonto Langkasa, Minasa Te’ne District, Pangkajene and Islands Regency. Methodology/approach: This activity was carried out in Bonto Langkasa with participating adolescent girls as the main target. The project adopted a participatory approach, including nutritional counseling, hands-on training using simple, locally sourced tools, and digital marketing workshops. Materials used were fresh milkfish, healthy additives, and packaging sourced from local markets. Pre- and post-tests, as well as follow-up surveys, were conducted to measure changes in knowledge, skills, and snack production rates. Results/findings: The program successfully increased participants’ knowledge about nutrition and practical skills in producing healthy milkfish-based snacks. Several participants started small-scale production, selling snacks in their communities. The project also improved participants' digital marketing competencies. Conclusion: Community service that focuses on innovative, healthy snacks using local resources, such as milkfish, can bridge nutritional knowledge-practice gaps, contribute to adolescent health, and foster economic opportunities for young women. This model is sustainable and replicable in other fishing communities. Limitations: Milkfish snack innovation is limited by simple technology, cultural preferences, basic nutritional focus, limited digital marketing, and narrow youth coverage, requiring further studies in other regions. Contribution: The contribution of this community service is to enhance nutritional knowledge, and develop healthy snack production skills, empower young women economically, optimize local milkfish production, and expand marketing through digital means.
Kemitraan Masyarakat Dalam Peningkatan Mutu dan Produksi VCO Mina Malole Rote Ndao Muntasir Muntasir; Muhajirin Dean; Matias Nataniel Kolobani; Cahyani Purnasari; Fatmawati Pua Upa
Jurnal Abdimas Multidisiplin Vol 4 No 1 (2025): Oktober
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/jamu.v4i1.5290

Abstract

Purpose: This community service program is designed to increase the quantity and quality of pure coconut oil production. through a partnership with Mitra Mina Malole. Methodology/approach: A participatory approach is implemented through training on VCO fermentation technology, mentoring on the use of appropriate tools, and regular implementation evaluations. The implementation team, comprising lecturers and students, collaborates directly with the partner community to transfer technology and monitor production outcomes. Results/findings: The community service program demonstrated an increase in production capacity, from 10–13 bottles per day to 20–25 bottles in 100 mL packaging, as well as improved product quality, resulting in a more hygienic and high-quality product. The product has obtained a P-IRT label and permit, and marketing has begun to expand, contributing to increased income and welfare for the local community. Conclutions: Community partnerships through appropriate technology and training have successfully improved the quality and production capacity of Virgin Coconut Oil in Ingguinak Village, increased family income, strengthened local business institutions, and expanded market access with more competitive and hygienic products. Limitations: The limited time for implementation means that ongoing support is still very much needed. Limited access to logistics and infrastructure in remote areas means that product distribution is not yet optimal. Contribution: This Program provides tangible socio-economic impacts for coconut farming communities. This program's recommendations can serve as a reference for developing broader community service policies and practices, supporting sustainable development, and strengthening local natural resource-based community economies.
The Role of artificial intelligence in the Development of Innovative Drugs and Therapies for the Future of Health Loso Judijanto; Rachmi Nurkhalika; Dito Anurogo; Soetji Andari; Muntasir Muntasir
Journal of World Future Medicine, Health and Nursing Vol. 2 No. 1 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/health.v2i1.666

Abstract

The development of artificial intelligence (AI) technology has made significant contributions to the healthcare field, especially in the development of innovative drugs and therapies. The combination of computational sophistication and AI data analysis has enabled researchers to identify complex patterns in biomedical data, accelerate drug discovery time, and facilitate therapy personalization. This research aims to explore the important role of AI in drug development and innovative therapies to create a better future of healthcare. This involves an analysis of various AI methods and techniques used in drug development as well as the application of AI in personalized therapy for society. This study was conducted by conducting a literature review and analyzing the latest research and developments in the application of AI in drug and therapy development. The results showed that AI has opened new opportunities in drug development by accelerating the process of drug target identification, molecular simulation, and optimization of clinical trials. Meanwhile, in therapeutics, AI enables better personalization through analysis of patient clinical data and prediction of response to specific treatments. This opens up the potential for the development of more effective and targeted therapies. With the development of AI technology, the development of innovative drugs and therapies has become more efficient and effective. The application of AI in healthcare offers the potential to create a more personalized, precise, and comprehensive healthcare future. The collaboration between medical science and AI technology will lead to more innovative and affordable health solutions for the people. Thus, the role of AI in the development of innovative drugs and therapies is recognized as one of the key pillars in creating a better future of healthcare.
Latest Innovations in the Treatment of Degenerative Diseases Lisma Natalia Br Sembiring; Aldiana Astuti; Muhammad Nazaruddin; Muntasir Muntasir; Dadang Muhammad Hasyim
Journal of World Future Medicine, Health and Nursing Vol. 2 No. 1 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/health.v2i1.718

Abstract

Recent innovations in the treatment of degenerative diseases have become a major focus of efforts to improve the quality of life of patients. With the development of technology and scientific research, there are opportunities to develop more effective and innovative treatment methods. In this study, we aim to explore recent innovations in the treatment of degenerative diseases, the purpose of which is to showcase the latest developments in the field of medicine that can provide new solutions in the management of degenerative diseases. The research method involved a literature review of recent studies in the treatment of degenerative diseases, as well as an analysis of relevant research data. The results showed some promising recent innovations, such as gene therapy, the use of stem cell technology, nanotechnology in drug delivery, and electromagnetic field approaches in medicine. These innovations offer the potential to improve treatment effectiveness and reduce the negative impact of these degenerative diseases. From the results of this study, it can be concluded that recent innovations in the treatment of degenerative diseases offer new hope in the management of these diseases. Technological developments and scientific research provide opportunities for the development of more effective and innovative treatment methods. However, despite significant progress in this field, further research is needed to evaluate the effectiveness, safety and sustainability of these innovations. This conclusion underscores the importance of collaboration between scientists, clinicians and the pharmaceutical industry to continue to drive innovation in an effort to holistically address degenerative diseases.
Co-Authors - Sri Prilmayanti Awaluddin, - Aan Suriadi Abdullah Abdullah Abdus Salam, Abdus Abu Bakar, Muhammad Bin Adu, Apris A. Afri, Lasarus Agus Setyobudi Agustin Mardiana, Nur Ai Nurhayati Akbar Awaluddin Aldi Benggu Aldiana Astuti Ali Omar Ali Warsito Alves, Livia Ambarwati, Rini Amelya Betsalonia Sir Anastasia Sofia L. Keraf Andari, Soetji Andarmoyo, Sulistyo Anderias Umbu Roga Andi Ummul Khair Andi ummul Khair Andreastra, Agustinus Putu Anggia Faradina Anggriani Angela Alim Antonius Rolling Basa Ola Aom Thai Ardila Nurjayastito Sulanjana Putri Asirah, Asirah Assel Zhanibek Astuti, Aldiana Aung Myint Baharuddin Baharuddin Baharuddin Baharuddin Bahruni . Benny Novico Zani Benny Novico Zani Berek, Norce Ch. Bimby Hidayat Buka, Sisilia Prima Yanuaria Cahyani Purnasari Cahyani Purnasari Chatrin Lenggu Choi Seojin Christin Rony Nayoan Christina Rony Nayoan Conrad L. H. Folamauk Dadang Muhammad Hasyim David B.W. Pandie Dawson Zulveritha Deddy Satria M Deni Anggreani Sutomo Dewi Sri Handayani Diana Catharina Yohanes Diki Prayugo Wibowo Dimas Rohman Ardiansyah Dionesia Octaviani Laput Dita Nurul Savitri Dito Anurogo Dito Anurogo Dito Anurogo, Dito Djati, Hyronymus Djawa, Agostin Nofembriyani Edon, Caro David Hadel Edwinandro V Salju Elisa Issusilaningtyas Elisabeth Novita Angriani L. Toruan Emily Nur Saidy Erny Erawati Pua Upa Ervina Indriyani Ethan Tan Eufrasia Prinata Padeng Fadhlur Rahman Faisal Razak Faradina, Anggia Farida Arinie Soelistianto Fatima Ahmed Fatmawati Pua Upa Fauzi Fauzi Fawzy, Nabiyl Ahmad Felipe Souza Fhahri Mubarak Fitriah Handayani Fitrya Rahmawaty Saleh Folamauk, Conrad Liab Hendricson Fransiska Nova Nanur Gracewati Rambu Ladu Day Gusnawati Gusnawati Hafaf Lutfiani Sani Haijal, Ahmad Halena Meldy Asa Halimatussakdiah Halimatussakdiah Halimatussakdiah Halimatussakdiah Hari Rarindo Hasnawati Husen Hendra Nusa Putra Hendra Nusa Putra Hetgen Palabuan Htwe, Thandar Idawati Trisno Iffah Atiqah Sari Ika Febianti Buntoro Imran, Un Dini Indah Raya Indra Mawardi Indrawan Azis Indriati A. Tedju Hinga Intan Kamala Aisyiah Iskandar Zulkarnaen Iskandar Zulkarnaen Ismail, Eddy H. Ismed Ismed Ismed Ismed Isymiarni Syarif Ivan Dimitrov Jackson Lee Jacob Matheos Ratu Januar Kulsaputro Jeane L.I. Sumarauw Jeanet Anggiany Sabaat Joko Sangaji Judijanto, Loso Junia Jessy Sarupy Junias, Marylin S. Kamaluddin, La Ode Amijaya Kamaruddin, Ilham Karolus Tokan, Yohanes Kenjam, Yoseph Khrisna Agung Cendekiawan Khusnul Dwi C Kikhau, Adriana M. O. Koamesah, Sangguana Marthen Jacobus Kolobani, Matias Nataniel Kuswara, Ketut Mahendra La Ode Amijaya Kamaluddin Lady Napedi Aome Laela Lenggu, Chatrin Jansye Lerik, M. Dinah Charlota Lewi Jutomo Listyawati Nurina Litik, Serlie Livia Alves Loda, Yohana Jawe Loso Judijanto Lucas Wong Luh Putu Rulianti M Dinah Charlota Lerik M Kurniawan Thalib M. Dinah Charlota Lerik M. Sjahrul M. Sjahrul Maidelwita, Yani Manafe, Ovlian Afri Manalu, Teacher Mandala, Damelia Manongga, SP. Manongga, Stefanus P Manurung, Imelda Februati Ester Margareta Elisabeth Kartona Aru Maria Antonia Nurak Maria Ermelinda Menge Bay Maria Faustina Arvidiani Maria Ivanova Mariana D.C. Lerik Mariana Paulina Putri Billa Marianus Ketmoen Marisa Sinlae Masrida Sinaga Masrida Sinaga Masrida Sinaga Mathias N. Kolobani Mathias N. Kolobani Mathias Nathaniel Kolobani Matias Nataniel Kolobani Matias Nataniel Kolobani MAURITZ PANDAPOTAN MARPAUNG Mayners, Marline Miksusanti Miksusanti Miksusanti Miksusanti Miksusanti Miksusanti Mozart Harpian Fereal Mori Uma Muhajirin Dean Muhammad Aminullah, Muhammad Muhammad Nazaruddin Muhammad Zakir Muhammad Zakir MULYADI Mustakin Sahdan Myint, Aung Nabuasa, Bernadeta Stien Julian Nadra Aga Iryani Nadra Aga Iryani Nadra Aga Iryani Nahak, Dominggus Florianus Naibaho, Netty Maria Nandar Hlaing Napitupulu, Melissa Putri M. Natalia Lisma Br Sembiring Neti Sulami Netty Maria Naibaho Nicholas Edwin Handoyo Nikosius Dae Sory Wutun Nizar Saputra Nofriana Inna Manulangga Noor Diah Erlinawati Nur Hasanah Nur Hasanah Nur, Marselinus Laga Nurani Ai Erlinawati Nurani Nurani Nurani Nurani Nurani Nurani Nurani Nurani Nurhikma Awaluddin Nurina, Rr. Listyawati Nurkhalika, Rachmi Nurlaela Nurlela Mariana Nababn Nurnainah Nurul Fatmawati Pua Upa Nurul Huda Nurviani, Rahima Oematan, Videl Apsi Panie, Chatrina H. Paula Tibuludji Perceka, Andhika Lungguh Pricilia Rilyn Restifanny Marolly Priyo Sasmito Purnawan, Sigit Putri, Hera Nur Rachmi Nurkhalika Radja Riwu, Yuliana Rasdi , Rasdi Refli Refli Regaletha, Tadeus A. L. Rina Waty Sirait Rini Ambarwati Riski Arisando Bahan Riski Dwi Prameswari Riski Dwi Prameswari Riwu, Magdarita Rizwan, Muhammad Rulianti, Luh Putu Rustam Rustam Rustam Rustam Rustan DM Rustan, Rustan Ryan Teo Sabina Gero Sabrina Doudou Safitri , Rizka Sahdan, Mustakim Saidy, Emily Nur Saldy Hapiwaty Salesman, Frans Salju, Edwinandro V Samat Yessentayev Sani, Hafaf Lutfiani Saputra, Ronni Sarah Williams Sarci M,Toy Sariyusda, Sariyusda SATRIYAS ILYAS Selvana Stien Tulandi Senci Marselin Beti Septania Rahmawati Ruth Taneo Serlie K.A. Littik Setianto, Rony Seubelan, Linda Sigit Purnawan Siri Lek Sisilia Prima Yanuaria Buka Siti Horidah Soelistianto, Farida Arinie Soetji Andari Soleman Landi Soleman Landi Souza, Felipe SP Manongga Sri Hartanti Masneno Sulistyo Andarmoyo Sumarauw, Jeane L.I. Sumayyah Jamal H. M. Arifin Suriati Lubis Syahdan, Mustakim Syauqi, Anis Tadeus A. L. Regaletha Tadeus A. L. Regaletha Tadeus AL. Regaletha Tadeus Andrea Lada Regaletha Tadeus Andreas Lada Regaletha Tadeus Andreas Lada Regaletha Tanty Rahayu Taty Noorhayati Thadeus A.L Regaletha Thalib, M Kurniawan Thandar Htwe Theodora Liefanda Bunga Titik Purwaningtyas Titu Eki , Ayub Ton Kiat Toy, Sarci M. Tulandi, Selvana Stien Tutik Wuryandari Un Dini Imran Un Dini Imran Upa, Fatmawati Pua Weraman, Pius Wijaya, R. Pasifikus Christa Wilanda, Alifah Wuryandari, Tutik Wutun, Nikosius Dae Sory Yani Maidelwita Yermia Djefri Manafe Yoseph Kenjam Yoseph Putra Albertino Mawo Zani, Benny Novico Zulham Zulkifli Halid